1JH1A

Crystal structure of mmp-8 complexed with a 6h-1,3,4-thiadiazine derived inhibitor
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
158
structure length
158
Chain Sequence
NPKWERTNLTYRIRNYTPQLSEAEVERAIKDAFELWSVASPLIFTRISQGEADINIAFYQRDHGDNSPFDGPNGILAHAFQPGQGIGGDAHFDAEETWTNTSANYNLFLVAAHEFGHSLGLAHSSDPGALMYPNYAFRETSNYSLPQDDIDGIQAIYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-based design and synthesis of potent matrix metalloproteinase inhibitors derived from a 6H-1,3,4-thiadiazine scaffold.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Matrix Metalloproteinase 8
total genus 45
structure length 158
sequence length 158
ec nomenclature ec 3.4.24.34: Neutrophil collagenase.
pdb deposition date 2001-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 1jh1A00
2OW0A 3KECA 1UMTA 2JNPA 2W0DA 2A8HA 2FV9A 4I35A 1QIAA 1Q3AA 3TSKA 4H76A 3G42A 1Y8JA 4L19A 1D7XA 3VTGA 3V96B 2E2DA 4ILWD 2W13A 1FM1A 3N2VA 3LE9A 1OS9A 2AYKA 2QPJA 1UMSA 1JJ9A 1KBCA 3F1AA 3B92A 3F17A 2SRTA 1OMJA 4FXYP 3USNA 2TCLA 1BIWA 3RTSA 1JK3A 1IAEA 1HY7A 2OY2A 1R1IA 3WV1A 1CGFA 5D7WA 4L6TA 3I7GA 1K7IA 4H82A 966CA 4A7BA 3DPEA 3LJGA 4H84A 3KRYA 3SHIA 1IADA 4GF1A 3E8RA 1SU3A 5BPAA 1SLNA 1G05A 2X3AA 4FXQA 1XURA 2OXZA 3KEJA 1IAAA 5LABA 1XFUA 3DNGA 4JQGA 2JT5A 2WO8A 2WO9A 3HBUP 2I47A 4WZVA 1OM8A 2HU6A 2CKIA 4WKIA 4PKQA 4PKRA 1BUVM 2AIGP 1KUIA 1XUDA 3N2UA 1MMQA 5D3CA 2OW9A 4XM6A 4IJOA 5L79A 1GE6A 4H49A 1GO7P 1YQYA 2CLTA 2X3BA 1XFZA 1MMBA 1HV5A 2MZEA 4JA1A 1O0TA 1L6JA 4GWMA 5D1UA 1A86A 1JAPA 5B5OA 1KUGA 2OVXA 1G12A 3DL1A 1J7NA 3ZXHA 2N8RA 3LQBA 3LJZA 2K2GA 3DWBA 3LIKA 2E3XA 2ERQA 1SATA 3HDBA 4AUOA 5CXAA 4G0DA 1JIZA 2PJTA 1G9KA 3LUMA 1BSWA 3KMEA 4EFSA 2W14A 5H8XA 3HYGA 3EHXA 1JAQA 1BZSA 1ROSA 2EROA 5D1SA 3U1RA 5I43A 1H71P 1PWUA 3OHLA 4GR3A 2RJPA 2OZRA 4WKEA 1G4KA 1D8FA 4ON1A 1G49A 4GWNA 1SLMA 4FU4A 5I4OA 1PWVA 3G5CA 2YB9A 1FBLA 1I73A 3LIRA 1S4BP 4PKUA 4PKWA 1ZS0A 1UTZA 1GKDA 4AYKA 3AYKA 1XFXA 4XBHA 1EAKA 2JSDA 3LUNA 2OXWA 2OW1A 1EB6A 2POJA 4CTHA 2OY4A 4DF9A 3L0TA 2L0RA 3AYUA 5CUHA 3ZUKA 1JAOA 1CK7A 1QUAA 2MZHA 2Z2DA 1HFCA 4DV8A 3O2XA 1ND1A 3EDHA 4IN9A 1BKCE 1JH1A 2MZIA 3K7LA 3NX7A 1XFYA 1YOUA 1HOVA 2XS3A 1ASTA 1CIZA 1BQOA 1HTDA 1I76A 3O64A 1OS2A 3HY7A 1OM6A 1ZTQA 3TVCA 1BKCA 4PKVA 3LMCA 1XFWA 3P24A 2X7MA 1YCMA 1BQQM 1D8MA 3DPFA 1I1IP 2O3EA 2OW2A 3LJTA 1JIWP 1UTTA 830CA 1QICA 3HDAP 4H3XA 3EDGA 456CA 2OVZA 1PWWA 4JP4A 1K7GA 1YP1A 1ZVXA 2K9CA 3HB2P 2D1OA 1FLSA 1R54A 2O36A 2V4BA 1R55A 1D5JA 3L0VA 2DW1A 3K7NA 5I12A 1UEAA 3ZVSA 3F19A 3EDIA 1RM8A 1Y0VA 3Q2HA 4WK7A 4I03A 3RTTA 2YIGA 3DSLA 1GE5A 3LEAA 1AF0A 1XUCA 1USNA 4IUWA 1SRPA 1PWQA 4Q1LA 2WOAA 1ZXCA 3TT4A 1C3IA 1PWPA 4XM8A 5CZMA 1CQRA 1HFSA 1RMZA 4R3VA 3BA0A 4GR0A 4HMAA 5BOYA 2W15A 1KUKA 4L63A 4GR8A 3F15A 3MA2A 5I2ZA 1ZP5A 5I0LA 1C7KA 1CXVA 2DW2A 3LQ0A 3HBVP 4PKSA 2X3CA 3KEKA 4A3WA 1Z3JA 1GE7A 4FVLA 2XS4A 5D1TA 3VI1A 3LGPA 5B5PA 1MNCA 1R1HA 2OI0A 1R1JA 2FV5A 1AKLA 4HX3A 4PKTA 1JANA 4G9LA 1BUDA 1OM7A 3UVCA 3F18A 4XCTA 2ERPA 4DPEA 1DMTA 1QJJA 1KAPP 3AIGA 3LK8A 1XFVA 1WNIA 3TS4A 1AYKA 1GKCA 4H2EA 5JMYA 4DD8A 1ATLA 3KWVC 1GO8P 1B3DA 3LILA 4H1QA 4ZR5A 1CAQA 1CGEA 2MLSA 1IABA 1OO9A 2DW0A 4JIJA 1B8YA 4WF6A 1A85A 3KMCA 2KRJA 1MMPA 2JT6A 3P1VA 3Q2GA 1QIBA 3EHYA 1K7QA 2J83A 1CGLA 2MLRA 3WV3A 2JIHA 3F16A 3ELMA 4AXQA 1DTHA 3HY9A 4J4MA 2USNA 3OHOA 1EUBA 1BKCI 4QKZA 1KUFA 2J0TA 3EDZA 3KHIA 3LKAA 1SMPA 3EWJA 1KUHA 1IAGA 4XM7A 2DDYA 2W12A 4H30A 2D1NA 2DDFA 5I3MA 3I7IA 3WV2A 3B8ZA 3B2ZA 1BM6A 1IACA 1QJIA 5BOTA 1MMRA 1GXDA 1Y93A 3CKIA 1O0QA 2Y6DA 5L7FA 1ZXVA 1JKYA 4AIGA 1C8TA 4JPAA 2Y6CA 2OXUA 5D2BA 3GBOA 2RJQA 4GQLA 4GUYA
chains in the Genus database with same CATH superfamily
2OW0A 3KECA 1UMTA 2JNPA 2W0DA 2A8HA 2FV9A 4I35A 1QIAA 1Q3AA 3TSKA 4H76A 3G42A 1Y8JA 4L19A 1D7XA 3VTGA 3V96B 2E2DA 4ILWD 4L7AA 2W13A 1FM1A 3N2VA 3LE9A 1OS9A 2AYKA 2QPJA 1OZ9A 1UMSA 1JJ9A 1KBCA 3F1AA 3B92A 3F17A 2SRTA 1OMJA 4FXYP 3USNA 2TCLA 1BIWA 3RTSA 1JK3A 1IAEA 1HY7A 2OY2A 1R1IA 3WV1A 1CGFA 5D7WA 4L6TA 3I7GA 1K7IA 4H82A 966CA 4A7BA 3DPEA 3LJGA 4H84A 3KRYA 3SHIA 1IADA 4GF1A 3E8RA 1SU3A 5BPAA 1SLNA 1G05A 2X3AA 4FXQA 1XURA 2OXZA 3KEJA 1IAAA 5LABA 1XFUA 3DNGA 4JQGA 2JT5A 2WO8A 2WO9A 3HBUP 2I47A 4WZVA 1OM8A 1TVIA 2HU6A 2CKIA 4WKIA 4PKQA 4PKRA 1BUVM 2AIGP 1KUIA 1XUDA 3N2UA 1MMQA 5D3CA 2OW9A 4XM6A 4IJOA 5L79A 1GE6A 4H49A 1GO7P 1YQYA 2CLTA 2X3BA 1XFZA 1MMBA 1HV5A 2MZEA 4JA1A 1O0TA 1L6JA 4GWMA 5D1UA 1A86A 1JAPA 5B5OA 1KUGA 2OVXA 1G12A 3DL1A 1J7NA 3ZXHA 2N8RA 3LQBA 3LJZA 2K2GA 3DWBA 3LIKA 2E3XA 2ERQA 1SATA 3HDBA 4AUOA 5CXAA 4G0DA 1JIZA 1XM5A 2PJTA 1G9KA 3LUMA 1BSWA 3KMEA 4EFSA 2W14A 5H8XA 3HYGA 3EHXA 1JAQA 1BZSA 1ROSA 2EROA 5D1SA 3U1RA 5I43A 1H71P 1PWUA 3OHLA 4GR3A 2RJPA 2OZRA 4WKEA 1G4KA 1D8FA 4ON1A 1G49A 4GWNA 1SLMA 4FU4A 5I4OA 1PWVA 3G5CA 2YB9A 1FBLA 1I73A 3LIRA 1S4BP 4PKUA 4PKWA 1ZS0A 1UTZA 1GKDA 4AYKA 3AYKA 1XFXA 4XBHA 1EAKA 2JSDA 3LUNA 2OXWA 2OW1A 1EB6A 2POJA 4CTHA 2OY4A 4DF9A 3L0TA 2L0RA 3AYUA 5CUHA 3ZUKA 1JAOA 1CK7A 1QUAA 2MZHA 2Z2DA 1HFCA 4DV8A 3O2XA 1ND1A 3EDHA 4IN9A 1BKCE 1JH1A 2MZIA 3K7LA 3NX7A 1XFYA 1YOUA 1HOVA 2XS3A 1ASTA 1CIZA 1BQOA 1HTDA 1I76A 3O64A 1OS2A 3DTKA 3HY7A 1OM6A 1ZTQA 3TVCA 1BKCA 3DTIA 4PKVA 3LMCA 1XFWA 3P24A 2X7MA 1YCMA 1BQQM 1D8MA 3DPFA 1I1IP 2O3EA 2OW2A 3LJTA 1JIWP 1UTTA 830CA 1QICA 3HDAP 4H3XA 3EDGA 456CA 2OVZA 1PWWA 4JP4A 1K7GA 1YP1A 1ZVXA 2K9CA 3HB2P 2D1OA 1FLSA 1R54A 2O36A 2V4BA 1R55A 1D5JA 3L0VA 2DW1A 3K7NA 5I12A 1UEAA 3ZVSA 3F19A 3EDIA 1RM8A 1Y0VA 3Q2HA 4WK7A 4I03A 3RTTA 2YIGA 3DSLA 1GE5A 3LEAA 1AF0A 1XUCA 1USNA 4IUWA 1SRPA 1PWQA 4Q1LA 2WOAA 1ZXCA 3TT4A 1C3IA 1PWPA 4XM8A 5CZMA 1CQRA 1HFSA 1RMZA 4R3VA 3BA0A 4GR0A 4HMAA 5BOYA 2W15A 1KUKA 4L63A 4GR8A 3F15A 3MA2A 2YUFA 5I2ZA 1ZP5A 5I0LA 1C7KA 1CXVA 2DW2A 3LQ0A 3HBVP 4PKSA 2X3CA 3KEKA 4A3WA 1Z3JA 1GE7A 4FVLA 2XS4A 5D1TA 3VI1A 3LGPA 5B5PA 1MNCA 1R1HA 2OI0A 1XAXA 1R1JA 2FV5A 1AKLA 4HX3A 4PKTA 1JANA 4G9LA 1BUDA 1OM7A 3UVCA 3F18A 4XCTA 2ERPA 4DPEA 1DMTA 1QJJA 1KAPP 3AIGA 3LK8A 1XFVA 1WNIA 3TS4A 1AYKA 1GKCA 4H2EA 5JMYA 4DD8A 1ATLA 3KWVC 1GO8P 1B3DA 3LILA 4H1QA 4ZR5A 1CAQA 1CGEA 3DTEA 2MLSA 1IABA 1OO9A 2DW0A 4JIJA 1B8YA 4WF6A 1A85A 3KMCA 2KRJA 1MMPA 2JT6A 3P1VA 3Q2GA 1QIBA 3EHYA 1K7QA 2J83A 1CGLA 2MLRA 3WV3A 2JIHA 3F16A 3ELMA 4AXQA 1DTHA 3HY9A 4J4MA 2USNA 3OHOA 1EUBA 1BKCI 4QKZA 1KUFA 2J0TA 3EDZA 3KHIA 3LKAA 1SMPA 3EWJA 1KUHA 1IAGA 4XM7A 2DDYA 2W12A 4H30A 2D1NA 2DDFA 5I3MA 3I7IA 3WV2A 3B8ZA 3B2ZA 1BM6A 1IACA 1QJIA 5BOTA 1MMRA 1GXDA 1Y93A 3CKIA 1O0QA 2Y6DA 5L7FA 1ZXVA 1JKYA 4AIGA 1C8TA 4JPAA 2Y6CA 2OXUA 5D2BA 3GBOA 2RJQA 4GQLA 4GUYA
chains in the Genus database with same CATH topology
2OW0A 3KECA 1UMTA 2JNPA 2W0DA 2A8HA 2FV9A 4I35A 1QIAA 1Q3AA 3TSKA 4H76A 3G42A 1Y8JA 4L19A 1D7XA 3VTGA 3V96B 2E2DA 4ILWD 4L7AA 2W13A 1FM1A 3N2VA 3LE9A 1OS9A 2AYKA 2QPJA 1UMSA 1JJ9A 1KBCA 3F1AA 3B92A 3F17A 2SRTA 1OMJA 4FXYP 3USNA 2TCLA 1BIWA 3RTSA 1JK3A 1IAEA 1HY7A 2OY2A 1R1IA 3WV1A 1CGFA 5D7WA 4L6TA 3I7GA 1K7IA 4H82A 966CA 4A7BA 3DPEA 3LJGA 4H84A 3KRYA 3SHIA 1IADA 4GF1A 3E8RA 1SU3A 5BPAA 1SLNA 1G05A 2X3AA 4FXQA 1XURA 2OXZA 3KEJA 1IAAA 5LABA 1XFUA 3DNGA 4JQGA 2JT5A 2WO8A 2WO9A 3HBUP 2I47A 4WZVA 1OM8A 2HU6A 2CKIA 4WKIA 4PKQA 4PKRA 1BUVM 2AIGP 1KUIA 1XUDA 3N2UA 1MMQA 5D3CA 2OW9A 4XM6A 4IJOA 5L79A 1GE6A 4H49A 1GO7P 1YQYA 2CLTA 2X3BA 1XFZA 1MMBA 1HV5A 2MZEA 4JA1A 1O0TA 1L6JA 4GWMA 5D1UA 1A86A 1JAPA 5B5OA 1KUGA 2OVXA 1G12A 3DL1A 1J7NA 3ZXHA 2N8RA 3LQBA 3LJZA 2K2GA 3DWBA 3LIKA 2E3XA 2ERQA 1SATA 3HDBA 4AUOA 5CXAA 4G0DA 1JIZA 2PJTA 1G9KA 3LUMA 1BSWA 3KMEA 4EFSA 2W14A 5H8XA 3HYGA 3EHXA 1JAQA 1BZSA 1ROSA 2EROA 5D1SA 3U1RA 5I43A 1H71P 1PWUA 3OHLA 4GR3A 2RJPA 2OZRA 4WKEA 1G4KA 1D8FA 4ON1A 1G49A 4GWNA 1SLMA 4FU4A 5I4OA 1PWVA 3G5CA 2YB9A 1FBLA 1I73A 3LIRA 1S4BP 4PKUA 4PKWA 1ZS0A 1UTZA 1GKDA 4AYKA 3AYKA 1XFXA 4XBHA 1EAKA 2JSDA 3LUNA 2OXWA 2OW1A 1EB6A 2POJA 4CTHA 2OY4A 4DF9A 3L0TA 2L0RA 3AYUA 5CUHA 3ZUKA 1JAOA 1CK7A 1QUAA 2MZHA 2Z2DA 1HFCA 4DV8A 3O2XA 1ND1A 3EDHA 4IN9A 1BKCE 1JH1A 2MZIA 3K7LA 3NX7A 1XFYA 1YOUA 1HOVA 2XS3A 1ASTA 1CIZA 1BQOA 1HTDA 1I76A 3O64A 1OS2A 3DTKA 3HY7A 1OM6A 1ZTQA 3TVCA 1BKCA 3DTIA 4PKVA 3LMCA 1XFWA 3P24A 2X7MA 1YCMA 1BQQM 1D8MA 3DPFA 1I1IP 2O3EA 2OW2A 3LJTA 1JIWP 1UTTA 830CA 1QICA 3HDAP 4H3XA 3EDGA 456CA 2OVZA 1PWWA 4JP4A 1K7GA 1YP1A 1ZVXA 2K9CA 3HB2P 2D1OA 1FLSA 1R54A 2O36A 2V4BA 1R55A 1D5JA 3L0VA 2DW1A 3K7NA 5I12A 1UEAA 3ZVSA 3F19A 3EDIA 1RM8A 1Y0VA 3Q2HA 4WK7A 4I03A 3RTTA 2YIGA 3DSLA 1GE5A 3LEAA 1AF0A 1XUCA 1USNA 4IUWA 1SRPA 1PWQA 4Q1LA 2WOAA 1ZXCA 3TT4A 1C3IA 1PWPA 4XM8A 5CZMA 1CQRA 1HFSA 1RMZA 4R3VA 3BA0A 4GR0A 4HMAA 5BOYA 2W15A 1KUKA 4L63A 4GR8A 3F15A 3MA2A 2YUFA 5I2ZA 1ZP5A 5I0LA 1C7KA 1CXVA 2DW2A 3LQ0A 3HBVP 4PKSA 2X3CA 3KEKA 4A3WA 1Z3JA 1GE7A 4FVLA 2XS4A 5D1TA 3VI1A 3LGPA 5B5PA 1MNCA 1R1HA 2OI0A 1R1JA 2FV5A 1AKLA 4HX3A 4PKTA 1JANA 4G9LA 1BUDA 1OM7A 3UVCA 3F18A 4XCTA 2ERPA 4DPEA 1DMTA 1QJJA 1KAPP 3AIGA 3LK8A 1XFVA 1WNIA 3TS4A 1AYKA 1GKCA 4H2EA 5JMYA 4DD8A 1ATLA 3KWVC 1GO8P 1B3DA 3LILA 4H1QA 4ZR5A 1CAQA 1CGEA 3DTEA 2MLSA 1IABA 1OO9A 2DW0A 4JIJA 1B8YA 4WF6A 1A85A 3KMCA 2KRJA 1MMPA 2JT6A 3P1VA 3Q2GA 1QIBA 3EHYA 1K7QA 2J83A 1CGLA 2MLRA 3WV3A 2JIHA 3F16A 3ELMA 4AXQA 1DTHA 3HY9A 4J4MA 2USNA 3OHOA 1EUBA 1BKCI 4QKZA 1KUFA 2J0TA 3EDZA 3KHIA 3LKAA 1SMPA 3EWJA 1KUHA 1IAGA 4XM7A 2DDYA 2W12A 4H30A 2D1NA 2DDFA 5I3MA 3I7IA 3WV2A 3B8ZA 3B2ZA 1BM6A 1IACA 1QJIA 5BOTA 1MMRA 1GXDA 1Y93A 3CKIA 1O0QA 2Y6DA 5L7FA 1ZXVA 1JKYA 4AIGA 1C8TA 4JPAA 2Y6CA 2OXUA 5D2BA 3GBOA 2RJQA 4GQLA 4GUYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OW0 A;  3KEC A;  1UMT A;  2JNP A;  2W0D A;  2A8H A;  2FV9 A;  4I35 A;  1QIA A;  1Q3A A;  3TSK A;  4H76 A;  3G42 A;  1Y8J A;  4L19 A;  1D7X A;  3VTG A;  3V96 B;  2E2D A;  4ILW D;  2W13 A;  1FM1 A;  3N2V A;  3LE9 A;  1OS9 A;  2AYK A;  2QPJ A;  1UMS A;  1JJ9 A;  1KBC A;  3F1A A;  3B92 A;  3F17 A;  2SRT A;  1OMJ A;  4FXY P;  3USN A;  2TCL A;  1BIW A;  3RTS A;  1JK3 A;  1IAE A;  1HY7 A;  2OY2 A;  1R1I A;  3WV1 A;  1CGF A;  5D7W A;  4L6T A;  3I7G A;  1K7I A;  4H82 A;  966C A;  4A7B A;  3DPE A;  3LJG A;  4H84 A;  3KRY A;  3SHI A;  1IAD A;  4GF1 A;  3E8R A;  1SU3 A;  5BPA A;  1SLN A;  1G05 A;  2X3A A;  4FXQ A;  1XUR A;  2OXZ A;  3KEJ A;  1IAA A;  5LAB A;  1XFU A;  3DNG A;  4JQG A;  2JT5 A;  2WO8 A;  2WO9 A;  3HBU P;  2I47 A;  4WZV A;  1OM8 A;  2HU6 A;  2CKI A;  4WKI A;  4PKQ A;  4PKR A;  1BUV M;  2AIG P;  1KUI A;  1XUD A;  3N2U A;  1MMQ A;  5D3C A;  2OW9 A;  4XM6 A;  4IJO A;  5L79 A;  1GE6 A;  4H49 A;  1GO7 P;  1YQY A;  2CLT A;  2X3B A;  1XFZ A;  1MMB A;  1HV5 A;  2MZE A;  4JA1 A;  1O0T A;  1L6J A;  4GWM A;  5D1U A;  1A86 A;  1JAP A;  5B5O A;  1KUG A;  2OVX A;  1G12 A;  3DL1 A;  1J7N A;  3ZXH A;  2N8R A;  3LQB A;  3LJZ A;  2K2G A;  3DWB A;  3LIK A;  2E3X A;  2ERQ A;  1SAT A;  3HDB A;  4AUO A;  5CXA A;  4G0D A;  1JIZ A;  2PJT A;  1G9K A;  3LUM A;  1BSW A;  3KME A;  4EFS A;  2W14 A;  5H8X A;  3HYG A;  3EHX A;  1JAQ A;  1BZS A;  1ROS A;  2ERO A;  5D1S A;  3U1R A;  5I43 A;  1H71 P;  1PWU A;  3OHL A;  4GR3 A;  2RJP A;  2OZR A;  4WKE A;  1G4K A;  1D8F A;  4ON1 A;  1G49 A;  4GWN A;  1SLM A;  4FU4 A;  5I4O A;  1PWV A;  3G5C A;  2YB9 A;  1FBL A;  1I73 A;  3LIR A;  1S4B P;  4PKU A;  4PKW A;  1ZS0 A;  1UTZ A;  1GKD A;  4AYK A;  3AYK A;  1XFX A;  4XBH A;  1EAK A;  2JSD A;  3LUN A;  2OXW A;  2OW1 A;  1EB6 A;  2POJ A;  4CTH A;  2OY4 A;  4DF9 A;  3L0T A;  2L0R A;  3AYU A;  5CUH A;  3ZUK A;  1JAO A;  1CK7 A;  1QUA A;  2MZH A;  2Z2D A;  1HFC A;  4DV8 A;  3O2X A;  1ND1 A;  3EDH A;  4IN9 A;  1BKC E;  1JH1 A;  2MZI A;  3K7L A;  3NX7 A;  1XFY A;  1YOU A;  1HOV A;  2XS3 A;  1AST A;  1CIZ A;  1BQO A;  1HTD A;  1I76 A;  3O64 A;  1OS2 A;  3HY7 A;  1OM6 A;  1ZTQ A;  3TVC A;  1BKC A;  4PKV A;  3LMC A;  1XFW A;  3P24 A;  2X7M A;  1YCM A;  1BQQ M;  1D8M A;  3DPF A;  1I1I P;  2O3E A;  2OW2 A;  3LJT A;  1JIW P;  1UTT A;  830C A;  1QIC A;  3HDA P;  4H3X A;  3EDG A;  456C A;  2OVZ A;  1PWW A;  4JP4 A;  1K7G A;  1YP1 A;  1ZVX A;  2K9C A;  3HB2 P;  2D1O A;  1FLS A;  1R54 A;  2O36 A;  2V4B A;  1R55 A;  1D5J A;  3L0V A;  2DW1 A;  3K7N A;  5I12 A;  1UEA A;  3ZVS A;  3F19 A;  3EDI A;  1RM8 A;  1Y0V A;  3Q2H A;  4WK7 A;  4I03 A;  3RTT A;  2YIG A;  3DSL A;  1GE5 A;  3LEA A;  1AF0 A;  1XUC A;  1USN A;  4IUW A;  1SRP A;  1PWQ A;  4Q1L A;  2WOA A;  1ZXC A;  3TT4 A;  1C3I A;  1PWP A;  4XM8 A;  5CZM A;  1CQR A;  1HFS A;  1RMZ A;  4R3V A;  3BA0 A;  4GR0 A;  4HMA A;  5BOY A;  2W15 A;  1KUK A;  4L63 A;  4GR8 A;  3F15 A;  3MA2 A;  5I2Z A;  1ZP5 A;  5I0L A;  1C7K A;  1CXV A;  2DW2 A;  3LQ0 A;  3HBV P;  4PKS A;  2X3C A;  3KEK A;  4A3W A;  1Z3J A;  1GE7 A;  4FVL A;  2XS4 A;  5D1T A;  3VI1 A;  3LGP A;  5B5P A;  1MNC A;  1R1H A;  2OI0 A;  1R1J A;  2FV5 A;  1AKL A;  4HX3 A;  4PKT A;  1JAN A;  4G9L A;  1BUD A;  1OM7 A;  3UVC A;  3F18 A;  4XCT A;  2ERP A;  4DPE A;  1DMT A;  1QJJ A;  1KAP P;  3AIG A;  3LK8 A;  1XFV A;  1WNI A;  3TS4 A;  1AYK A;  1GKC A;  4H2E A;  5JMY A;  4DD8 A;  1ATL A;  3KWV C;  1GO8 P;  1B3D A;  3LIL A;  4H1Q A;  4ZR5 A;  1CAQ A;  1CGE A;  2MLS A;  1IAB A;  1OO9 A;  2DW0 A;  4JIJ A;  1B8Y A;  4WF6 A;  1A85 A;  3KMC A;  2KRJ A;  1MMP A;  2JT6 A;  3P1V A;  3Q2G A;  1QIB A;  3EHY A;  1K7Q A;  2J83 A;  1CGL A;  2MLR A;  3WV3 A;  2JIH A;  3F16 A;  3ELM A;  4AXQ A;  1DTH A;  3HY9 A;  4J4M A;  2USN A;  3OHO A;  1EUB A;  1BKC I;  4QKZ A;  1KUF A;  2J0T A;  3EDZ A;  3KHI A;  3LKA A;  1SMP A;  3EWJ A;  1KUH A;  1IAG A;  4XM7 A;  2DDY A;  2W12 A;  4H30 A;  2D1N A;  2DDF A;  5I3M A;  3I7I A;  3WV2 A;  3B8Z A;  3B2Z A;  1BM6 A;  1IAC A;  1QJI A;  5BOT A;  1MMR A;  1GXD A;  1Y93 A;  3CKI A;  1O0Q A;  2Y6D A;  5L7F A;  1ZXV A;  1JKY A;  4AIG A;  1C8T A;  4JPA A;  2Y6C A;  2OXU A;  5D2B A;  3GBO A;  2RJQ A;  4GQL A;  4GUY A; 
#chains in the Genus database with same CATH topology
 2OW0 A;  3KEC A;  1UMT A;  2JNP A;  2W0D A;  2A8H A;  2FV9 A;  4I35 A;  1QIA A;  1Q3A A;  3TSK A;  4H76 A;  3G42 A;  1Y8J A;  4L19 A;  1D7X A;  3VTG A;  3V96 B;  2E2D A;  4ILW D;  4L7A A;  2W13 A;  1FM1 A;  3N2V A;  3LE9 A;  1OS9 A;  2AYK A;  2QPJ A;  1OZ9 A;  1UMS A;  1JJ9 A;  1KBC A;  3F1A A;  3B92 A;  3F17 A;  2SRT A;  1OMJ A;  4FXY P;  3USN A;  2TCL A;  1BIW A;  3RTS A;  1JK3 A;  1IAE A;  1HY7 A;  2OY2 A;  1R1I A;  3WV1 A;  1CGF A;  5D7W A;  4L6T A;  3I7G A;  1K7I A;  4H82 A;  966C A;  4A7B A;  3DPE A;  3LJG A;  4H84 A;  3KRY A;  3SHI A;  1IAD A;  4GF1 A;  3E8R A;  1SU3 A;  5BPA A;  1SLN A;  1G05 A;  2X3A A;  4FXQ A;  1XUR A;  2OXZ A;  3KEJ A;  1IAA A;  5LAB A;  1XFU A;  3DNG A;  4JQG A;  2JT5 A;  2WO8 A;  2WO9 A;  3HBU P;  2I47 A;  4WZV A;  1OM8 A;  1TVI A;  2HU6 A;  2CKI A;  4WKI A;  4PKQ A;  4PKR A;  1BUV M;  2AIG P;  1KUI A;  1XUD A;  3N2U A;  1MMQ A;  5D3C A;  2OW9 A;  4XM6 A;  4IJO A;  5L79 A;  1GE6 A;  4H49 A;  1GO7 P;  1YQY A;  2CLT A;  2X3B A;  1XFZ A;  1MMB A;  1HV5 A;  2MZE A;  4JA1 A;  1O0T A;  1L6J A;  4GWM A;  5D1U A;  1A86 A;  1JAP A;  5B5O A;  1KUG A;  2OVX A;  1G12 A;  3DL1 A;  1J7N A;  3ZXH A;  2N8R A;  3LQB A;  3LJZ A;  2K2G A;  3DWB A;  3LIK A;  2E3X A;  2ERQ A;  1SAT A;  3HDB A;  4AUO A;  5CXA A;  4G0D A;  1JIZ A;  1XM5 A;  2PJT A;  1G9K A;  3LUM A;  1BSW A;  3KME A;  4EFS A;  2W14 A;  5H8X A;  3HYG A;  3EHX A;  1JAQ A;  1BZS A;  1ROS A;  2ERO A;  5D1S A;  3U1R A;  5I43 A;  1H71 P;  1PWU A;  3OHL A;  4GR3 A;  2RJP A;  2OZR A;  4WKE A;  1G4K A;  1D8F A;  4ON1 A;  1G49 A;  4GWN A;  1SLM A;  4FU4 A;  5I4O A;  1PWV A;  3G5C A;  2YB9 A;  1FBL A;  1I73 A;  3LIR A;  1S4B P;  4PKU A;  4PKW A;  1ZS0 A;  1UTZ A;  1GKD A;  4AYK A;  3AYK A;  1XFX A;  4XBH A;  1EAK A;  2JSD A;  3LUN A;  2OXW A;  2OW1 A;  1EB6 A;  2POJ A;  4CTH A;  2OY4 A;  4DF9 A;  3L0T A;  2L0R A;  3AYU A;  5CUH A;  3ZUK A;  1JAO A;  1CK7 A;  1QUA A;  2MZH A;  2Z2D A;  1HFC A;  4DV8 A;  3O2X A;  1ND1 A;  3EDH A;  4IN9 A;  1BKC E;  1JH1 A;  2MZI A;  3K7L A;  3NX7 A;  1XFY A;  1YOU A;  1HOV A;  2XS3 A;  1AST A;  1CIZ A;  1BQO A;  1HTD A;  1I76 A;  3O64 A;  1OS2 A;  3DTK A;  3HY7 A;  1OM6 A;  1ZTQ A;  3TVC A;  1BKC A;  3DTI A;  4PKV A;  3LMC A;  1XFW A;  3P24 A;  2X7M A;  1YCM A;  1BQQ M;  1D8M A;  3DPF A;  1I1I P;  2O3E A;  2OW2 A;  3LJT A;  1JIW P;  1UTT A;  830C A;  1QIC A;  3HDA P;  4H3X A;  3EDG A;  456C A;  2OVZ A;  1PWW A;  4JP4 A;  1K7G A;  1YP1 A;  1ZVX A;  2K9C A;  3HB2 P;  2D1O A;  1FLS A;  1R54 A;  2O36 A;  2V4B A;  1R55 A;  1D5J A;  3L0V A;  2DW1 A;  3K7N A;  5I12 A;  1UEA A;  3ZVS A;  3F19 A;  3EDI A;  1RM8 A;  1Y0V A;  3Q2H A;  4WK7 A;  4I03 A;  3RTT A;  2YIG A;  3DSL A;  1GE5 A;  3LEA A;  1AF0 A;  1XUC A;  1USN A;  4IUW A;  1SRP A;  1PWQ A;  4Q1L A;  2WOA A;  1ZXC A;  3TT4 A;  1C3I A;  1PWP A;  4XM8 A;  5CZM A;  1CQR A;  1HFS A;  1RMZ A;  4R3V A;  3BA0 A;  4GR0 A;  4HMA A;  5BOY A;  2W15 A;  1KUK A;  4L63 A;  4GR8 A;  3F15 A;  3MA2 A;  2YUF A;  5I2Z A;  1ZP5 A;  5I0L A;  1C7K A;  1CXV A;  2DW2 A;  3LQ0 A;  3HBV P;  4PKS A;  2X3C A;  3KEK A;  4A3W A;  1Z3J A;  1GE7 A;  4FVL A;  2XS4 A;  5D1T A;  3VI1 A;  3LGP A;  5B5P A;  1MNC A;  1R1H A;  2OI0 A;  1XAX A;  1R1J A;  2FV5 A;  1AKL A;  4HX3 A;  4PKT A;  1JAN A;  4G9L A;  1BUD A;  1OM7 A;  3UVC A;  3F18 A;  4XCT A;  2ERP A;  4DPE A;  1DMT A;  1QJJ A;  1KAP P;  3AIG A;  3LK8 A;  1XFV A;  1WNI A;  3TS4 A;  1AYK A;  1GKC A;  4H2E A;  5JMY A;  4DD8 A;  1ATL A;  3KWV C;  1GO8 P;  1B3D A;  3LIL A;  4H1Q A;  4ZR5 A;  1CAQ A;  1CGE A;  3DTE A;  2MLS A;  1IAB A;  1OO9 A;  2DW0 A;  4JIJ A;  1B8Y A;  4WF6 A;  1A85 A;  3KMC A;  2KRJ A;  1MMP A;  2JT6 A;  3P1V A;  3Q2G A;  1QIB A;  3EHY A;  1K7Q A;  2J83 A;  1CGL A;  2MLR A;  3WV3 A;  2JIH A;  3F16 A;  3ELM A;  4AXQ A;  1DTH A;  3HY9 A;  4J4M A;  2USN A;  3OHO A;  1EUB A;  1BKC I;  4QKZ A;  1KUF A;  2J0T A;  3EDZ A;  3KHI A;  3LKA A;  1SMP A;  3EWJ A;  1KUH A;  1IAG A;  4XM7 A;  2DDY A;  2W12 A;  4H30 A;  2D1N A;  2DDF A;  5I3M A;  3I7I A;  3WV2 A;  3B8Z A;  3B2Z A;  1BM6 A;  1IAC A;  1QJI A;  5BOT A;  1MMR A;  1GXD A;  1Y93 A;  3CKI A;  1O0Q A;  2Y6D A;  5L7F A;  1ZXV A;  1JKY A;  4AIG A;  1C8T A;  4JPA A;  2Y6C A;  2OXU A;  5D2B A;  3GBO A;  2RJQ A;  4GQL A;  4GUY A; 
#chains in the Genus database with same CATH homology
 2OW0 A;  3KEC A;  1UMT A;  2JNP A;  2W0D A;  2A8H A;  2FV9 A;  4I35 A;  1QIA A;  1Q3A A;  3TSK A;  4H76 A;  3G42 A;  1Y8J A;  4L19 A;  1D7X A;  3VTG A;  3V96 B;  2E2D A;  4ILW D;  4L7A A;  2W13 A;  1FM1 A;  3N2V A;  3LE9 A;  1OS9 A;  2AYK A;  2QPJ A;  1UMS A;  1JJ9 A;  1KBC A;  3F1A A;  3B92 A;  3F17 A;  2SRT A;  1OMJ A;  4FXY P;  3USN A;  2TCL A;  1BIW A;  3RTS A;  1JK3 A;  1IAE A;  1HY7 A;  2OY2 A;  1R1I A;  3WV1 A;  1CGF A;  5D7W A;  4L6T A;  3I7G A;  1K7I A;  4H82 A;  966C A;  4A7B A;  3DPE A;  3LJG A;  4H84 A;  3KRY A;  3SHI A;  1IAD A;  4GF1 A;  3E8R A;  1SU3 A;  5BPA A;  1SLN A;  1G05 A;  2X3A A;  4FXQ A;  1XUR A;  2OXZ A;  3KEJ A;  1IAA A;  5LAB A;  1XFU A;  3DNG A;  4JQG A;  2JT5 A;  2WO8 A;  2WO9 A;  3HBU P;  2I47 A;  4WZV A;  1OM8 A;  2HU6 A;  2CKI A;  4WKI A;  4PKQ A;  4PKR A;  1BUV M;  2AIG P;  1KUI A;  1XUD A;  3N2U A;  1MMQ A;  5D3C A;  2OW9 A;  4XM6 A;  4IJO A;  5L79 A;  1GE6 A;  4H49 A;  1GO7 P;  1YQY A;  2CLT A;  2X3B A;  1XFZ A;  1MMB A;  1HV5 A;  2MZE A;  4JA1 A;  1O0T A;  1L6J A;  4GWM A;  5D1U A;  1A86 A;  1JAP A;  5B5O A;  1KUG A;  2OVX A;  1G12 A;  3DL1 A;  1J7N A;  3ZXH A;  2N8R A;  3LQB A;  3LJZ A;  2K2G A;  3DWB A;  3LIK A;  2E3X A;  2ERQ A;  1SAT A;  3HDB A;  4AUO A;  5CXA A;  4G0D A;  1JIZ A;  2PJT A;  1G9K A;  3LUM A;  1BSW A;  3KME A;  4EFS A;  2W14 A;  5H8X A;  3HYG A;  3EHX A;  1JAQ A;  1BZS A;  1ROS A;  2ERO A;  5D1S A;  3U1R A;  5I43 A;  1H71 P;  1PWU A;  3OHL A;  4GR3 A;  2RJP A;  2OZR A;  4WKE A;  1G4K A;  1D8F A;  4ON1 A;  1G49 A;  4GWN A;  1SLM A;  4FU4 A;  5I4O A;  1PWV A;  3G5C A;  2YB9 A;  1FBL A;  1I73 A;  3LIR A;  1S4B P;  4PKU A;  4PKW A;  1ZS0 A;  1UTZ A;  1GKD A;  4AYK A;  3AYK A;  1XFX A;  4XBH A;  1EAK A;  2JSD A;  3LUN A;  2OXW A;  2OW1 A;  1EB6 A;  2POJ A;  4CTH A;  2OY4 A;  4DF9 A;  3L0T A;  2L0R A;  3AYU A;  5CUH A;  3ZUK A;  1JAO A;  1CK7 A;  1QUA A;  2MZH A;  2Z2D A;  1HFC A;  4DV8 A;  3O2X A;  1ND1 A;  3EDH A;  4IN9 A;  1BKC E;  1JH1 A;  2MZI A;  3K7L A;  3NX7 A;  1XFY A;  1YOU A;  1HOV A;  2XS3 A;  1AST A;  1CIZ A;  1BQO A;  1HTD A;  1I76 A;  3O64 A;  1OS2 A;  3DTK A;  3HY7 A;  1OM6 A;  1ZTQ A;  3TVC A;  1BKC A;  3DTI A;  4PKV A;  3LMC A;  1XFW A;  3P24 A;  2X7M A;  1YCM A;  1BQQ M;  1D8M A;  3DPF A;  1I1I P;  2O3E A;  2OW2 A;  3LJT A;  1JIW P;  1UTT A;  830C A;  1QIC A;  3HDA P;  4H3X A;  3EDG A;  456C A;  2OVZ A;  1PWW A;  4JP4 A;  1K7G A;  1YP1 A;  1ZVX A;  2K9C A;  3HB2 P;  2D1O A;  1FLS A;  1R54 A;  2O36 A;  2V4B A;  1R55 A;  1D5J A;  3L0V A;  2DW1 A;  3K7N A;  5I12 A;  1UEA A;  3ZVS A;  3F19 A;  3EDI A;  1RM8 A;  1Y0V A;  3Q2H A;  4WK7 A;  4I03 A;  3RTT A;  2YIG A;  3DSL A;  1GE5 A;  3LEA A;  1AF0 A;  1XUC A;  1USN A;  4IUW A;  1SRP A;  1PWQ A;  4Q1L A;  2WOA A;  1ZXC A;  3TT4 A;  1C3I A;  1PWP A;  4XM8 A;  5CZM A;  1CQR A;  1HFS A;  1RMZ A;  4R3V A;  3BA0 A;  4GR0 A;  4HMA A;  5BOY A;  2W15 A;  1KUK A;  4L63 A;  4GR8 A;  3F15 A;  3MA2 A;  2YUF A;  5I2Z A;  1ZP5 A;  5I0L A;  1C7K A;  1CXV A;  2DW2 A;  3LQ0 A;  3HBV P;  4PKS A;  2X3C A;  3KEK A;  4A3W A;  1Z3J A;  1GE7 A;  4FVL A;  2XS4 A;  5D1T A;  3VI1 A;  3LGP A;  5B5P A;  1MNC A;  1R1H A;  2OI0 A;  1R1J A;  2FV5 A;  1AKL A;  4HX3 A;  4PKT A;  1JAN A;  4G9L A;  1BUD A;  1OM7 A;  3UVC A;  3F18 A;  4XCT A;  2ERP A;  4DPE A;  1DMT A;  1QJJ A;  1KAP P;  3AIG A;  3LK8 A;  1XFV A;  1WNI A;  3TS4 A;  1AYK A;  1GKC A;  4H2E A;  5JMY A;  4DD8 A;  1ATL A;  3KWV C;  1GO8 P;  1B3D A;  3LIL A;  4H1Q A;  4ZR5 A;  1CAQ A;  1CGE A;  3DTE A;  2MLS A;  1IAB A;  1OO9 A;  2DW0 A;  4JIJ A;  1B8Y A;  4WF6 A;  1A85 A;  3KMC A;  2KRJ A;  1MMP A;  2JT6 A;  3P1V A;  3Q2G A;  1QIB A;  3EHY A;  1K7Q A;  2J83 A;  1CGL A;  2MLR A;  3WV3 A;  2JIH A;  3F16 A;  3ELM A;  4AXQ A;  1DTH A;  3HY9 A;  4J4M A;  2USN A;  3OHO A;  1EUB A;  1BKC I;  4QKZ A;  1KUF A;  2J0T A;  3EDZ A;  3KHI A;  3LKA A;  1SMP A;  3EWJ A;  1KUH A;  1IAG A;  4XM7 A;  2DDY A;  2W12 A;  4H30 A;  2D1N A;  2DDF A;  5I3M A;  3I7I A;  3WV2 A;  3B8Z A;  3B2Z A;  1BM6 A;  1IAC A;  1QJI A;  5BOT A;  1MMR A;  1GXD A;  1Y93 A;  3CKI A;  1O0Q A;  2Y6D A;  5L7F A;  1ZXV A;  1JKY A;  4AIG A;  1C8T A;  4JPA A;  2Y6C A;  2OXU A;  5D2B A;  3GBO A;  2RJQ A;  4GQL A;  4GUY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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