1OS2A

Ternary enzyme-product-inhibitor complexes of human mmp12
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
165
structure length
165
Chain Sequence
MMGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYGDPKEN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray Structures of Binary and Ternary Enzyme-Product-Inhibitor Complexes of Matrix Metalloproteinases
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Macrophage metalloelastase
total genus 42
structure length 165
sequence length 165
chains with identical sequence B, C, D, E, F
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2003-03-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 1os2A00
3AYUA 1B3DA 2Z2DA 1JANA 3U1RA 1KUHA 5D1SA 4PKWA 2OW1A 1O0TA 3HYGA 1IAAA 4IN9A 5BPAA 1JAOA 1AKLA 2JSDA 5JMYA 4G9LA 1OO9A 4FXYP 4XM6A 2X3BA 3HY7A 1GE5A 3DPEA 2OY4A 1IABA 3B92A 4A7BA 4JQGA 1QJIA 1CGEA 2K9CA 1IACA 5D1UA 2OI0A 1RM8A 1Q3AA 3LQBA 3KRYA 2JT6A 4JIJA 4PKTA 1SU3A 2DDFA 1UTZA 1K7QA 2EROA 1D7XA 2W14A 1C3IA 2DW1A 2MLSA 2DW2A 3LILA 4H84A 1D8MA 1G9KA 3RTSA 4GR8A 1GXDA 3KWVC 1ZTQA 1PWVA 3G42A 3K7LA 4XM8A 4DF9A 3N2UA 4GR3A 4R3VA 2KRJA 3ELMA 3N2VA 1A86A 3BA0A 2D1NA 2J83A 4WKEA 1BUDA 1OM7A 1BZSA 3HB2P 1BKCA 1AF0A 1G12A 5CXAA 2XS4A 456CA 1G4KA 1ROSA 4AUOA 1A85A 2AYKA 3F15A 4JP4A 2OXWA 1JK3A 1BQOA 3L0VA 3HBUP 2J0TA 3ZVSA 2MZEA 4HX3A 2X7MA 3CKIA 1KBCA 1MMRA 1SMPA 3P24A 1SLMA 1KUFA 4J4MA 1DTHA 1Y93A 1HFSA 3DPFA 1OMJA 4H82A 3F1AA 1QIBA 5L79A 1SLNA 1MNCA 4H30A 1C8TA 1KAPP 3HDBA 3K7NA 1PWPA 4XM7A 3OHLA 3DWBA 4QKZA 1OM8A 5LABA 1RMZA 3I7IA 1G49A 4WZVA 1I1IP 4AYKA 4XBHA 2XS3A 2DW0A 1XFWA 1CIZA 1HOVA 3TT4A 3DL1A 1C7KA 2E3XA 2OZRA 2O3EA 2X3CA 1HY7A 5I43A 4L19A 2RJPA 4FXQA 2I47A 5CZMA 4I03A 3V96B 2W12A 1Z3JA 3LKAA 3LEAA 3KMCA 2D1OA 2MLRA 3O2XA 1BKCI 1YCMA 4PKRA 1R54A 1IAEA 1R55A 2OW2A 3F17A 1AYKA 1YQYA 5B5OA 2WO9A 1OM6A 5I2ZA 2OVZA 4GR0A 4GWMA 1KUIA 3LE9A 2A8HA 1BSWA 4DD8A 1QUAA 3LJZA 1BKCE 4DV8A 1JKYA 1BQQM 1FM1A 1KUGA 3KHIA 2TCLA 1SATA 1CXVA 1YP1A 1EB6A 1IAGA 3HBVP 1YOUA 3WV3A 1XFXA 4JA1A 3AYKA 4JPAA 4ZR5A 3LJGA 3EWJA 4WK7A 3WV2A 1ND1A 4L63A 1I76A 1XUCA 3P1VA 1R1HA 3LIKA 3ZUKA 1ASTA 4GUYA 5D1TA 2AIGP 3LMCA 5H8XA 1K7GA 1XFUA 2OW0A 4EFSA 1ZS0A 3LQ0A 2K2GA 1OS2A 1B8YA 3AIGA 4CTHA 5BOTA 1PWQA 3LGPA 1H71P 4I35A 1Y8JA 2YIGA 4WF6A 1K7IA 5D3CA 1FLSA 1WNIA 1ATLA 3HY9A 3SHIA 4H49A 1XFZA 1IADA 3KECA 2HU6A 4WKIA 3ZXHA 2RJQA 2V4BA 1USNA 3VTGA 5BOYA 5I12A 1JIWP 1I73A 3F16A 4Q1LA 1OS9A 2SRTA 2W0DA 1S4BP 3WV1A 3KEJA 1D5JA 2DDYA 2JNPA 3G5CA 3EDZA 1ZVXA 4FU4A 4IUWA 966CA 4FVLA 1J7NA 3L0TA 1L6JA 4PKQA 1XFYA 2WO8A 5L7FA 2MZIA 3LK8A 1Y0VA 2OVXA 4XCTA 1ZP5A 2FV9A 2CLTA 5D7WA 3VI1A 2N8RA 5I3MA 2POJA 1JH1A 3DNGA 2USNA 4AXQA 1ZXVA 1O0QA 1QJJA 1R1IA 4GQLA 1QICA 2E2DA 2QPJA 4L6TA 3EHYA 3NX7A 3DSLA 3E8RA 1XUDA 2WOAA 3F18A 1MMPA 1SRPA 4PKVA 5D2BA 1FBLA 3KEKA 4A3WA 3UVCA 4ILWD 2Y6DA 2CKIA 1GO7P 3O64A 1UMSA 3LJTA 3EDGA 4HMAA 3B8ZA 1JIZA 1DMTA 1GKDA 3I7GA 2OXUA 3OHOA 2ERQA 1PWUA 1ZXCA 3USNA 1GE6A 1GO8P 3KMEA 3RTTA 3Q2GA 1CQRA 1BM6A 2ERPA 3F19A 5B5PA 1XURA 1MMQA 4IJOA 2JT5A 2MZHA 2OY2A 1CGFA 2Y6CA 2X3AA 1G05A 1CGLA 5CUHA 4H1QA 4PKSA 3B2ZA 1R1JA 1CK7A 1XFVA 3HDAP 3LUMA 1UEAA 4PKUA 3TSKA 2L0RA 2O36A 4H3XA 1HTDA 1MMBA 3GBOA 5I4OA 1HFCA 1JAQA 1HV5A 3TS4A 1PWWA 830CA 1UTTA 2W15A 1QIAA 1EUBA 2JIHA 4DPEA 1KUKA 1D8FA 1GE7A 3EDHA 3LUNA 4H2EA 5I0LA 1EAKA 4AIGA 3Q2HA 4H76A 1UMTA 2OW9A 4GWNA 3MA2A 1BUVM 3EHXA 4GF1A 1JJ9A 1JAPA 2YB9A 1BIWA 3LIRA 2OXZA 2W13A 1GKCA 2FV5A 4ON1A 3TVCA 3EDIA 2PJTA 4G0DA 1CAQA
chains in the Genus database with same CATH superfamily
3AYUA 1B3DA 2Z2DA 1JANA 3U1RA 1KUHA 4L7AA 5D1SA 4PKWA 2OW1A 1O0TA 3HYGA 1IAAA 4IN9A 5BPAA 1JAOA 1AKLA 2JSDA 5JMYA 4G9LA 1OO9A 4FXYP 4XM6A 2X3BA 3HY7A 1GE5A 3DPEA 2OY4A 1IABA 3B92A 4A7BA 4JQGA 1QJIA 1CGEA 2K9CA 1IACA 5D1UA 2OI0A 1RM8A 1Q3AA 3LQBA 3KRYA 2JT6A 4JIJA 4PKTA 1SU3A 2DDFA 3DTKA 1UTZA 1K7QA 2EROA 1D7XA 2W14A 1C3IA 2DW1A 2MLSA 2DW2A 3LILA 4H84A 1D8MA 1G9KA 3RTSA 4GR8A 1GXDA 3KWVC 1ZTQA 1PWVA 3G42A 3K7LA 4XM8A 4DF9A 3N2UA 4GR3A 4R3VA 2KRJA 3ELMA 3N2VA 1A86A 3BA0A 2D1NA 2J83A 4WKEA 1BUDA 1OM7A 1BZSA 3HB2P 1BKCA 1AF0A 1G12A 5CXAA 2XS4A 456CA 1G4KA 1ROSA 4AUOA 1A85A 2AYKA 3F15A 4JP4A 2OXWA 1JK3A 1BQOA 3L0VA 3HBUP 2J0TA 3ZVSA 2MZEA 4HX3A 2X7MA 3CKIA 1KBCA 1MMRA 1SMPA 3P24A 1SLMA 1KUFA 4J4MA 1DTHA 1Y93A 1HFSA 3DPFA 1OMJA 4H82A 3F1AA 1QIBA 5L79A 1SLNA 1MNCA 4H30A 1C8TA 1KAPP 3HDBA 3K7NA 1PWPA 4XM7A 3OHLA 3DWBA 4QKZA 1OM8A 5LABA 1RMZA 3I7IA 1G49A 4WZVA 1I1IP 3DTEA 4AYKA 4XBHA 2XS3A 2DW0A 1XFWA 1CIZA 1HOVA 3TT4A 3DL1A 1C7KA 2E3XA 2OZRA 2O3EA 2X3CA 1HY7A 5I43A 4L19A 2RJPA 4FXQA 2I47A 5CZMA 4I03A 3V96B 2W12A 1Z3JA 3LKAA 3LEAA 3KMCA 2D1OA 2MLRA 3O2XA 1BKCI 1YCMA 4PKRA 1R54A 1IAEA 1R55A 2OW2A 3F17A 1AYKA 1YQYA 5B5OA 2WO9A 1OM6A 5I2ZA 2OVZA 4GR0A 4GWMA 1KUIA 3LE9A 2A8HA 1BSWA 4DD8A 1QUAA 3LJZA 1BKCE 4DV8A 1JKYA 1BQQM 1FM1A 1KUGA 3KHIA 2TCLA 1SATA 1CXVA 1YP1A 1EB6A 1IAGA 3HBVP 1YOUA 3WV3A 3DTIA 1XFXA 4JA1A 3AYKA 4JPAA 4ZR5A 3LJGA 3EWJA 4WK7A 3WV2A 1ND1A 4L63A 1I76A 1XUCA 3P1VA 1R1HA 3LIKA 3ZUKA 1ASTA 4GUYA 5D1TA 2AIGP 3LMCA 5H8XA 1K7GA 1XFUA 2OW0A 4EFSA 1ZS0A 3LQ0A 2K2GA 1OS2A 1B8YA 3AIGA 4CTHA 5BOTA 1PWQA 3LGPA 1H71P 4I35A 1Y8JA 2YIGA 4WF6A 1K7IA 5D3CA 1FLSA 1WNIA 1ATLA 3HY9A 3SHIA 4H49A 1XFZA 1IADA 3KECA 2HU6A 4WKIA 3ZXHA 2RJQA 2V4BA 1USNA 3VTGA 5BOYA 5I12A 1JIWP 1I73A 3F16A 4Q1LA 1OS9A 2SRTA 2W0DA 1S4BP 3WV1A 3KEJA 1D5JA 2DDYA 2JNPA 3G5CA 3EDZA 1ZVXA 4FU4A 4IUWA 966CA 4FVLA 1J7NA 2YUFA 3L0TA 1L6JA 4PKQA 1XFYA 2WO8A 5L7FA 2MZIA 3LK8A 1Y0VA 2OVXA 4XCTA 1ZP5A 2FV9A 2CLTA 5D7WA 3VI1A 2N8RA 5I3MA 2POJA 1JH1A 3DNGA 2USNA 4AXQA 1ZXVA 1O0QA 1QJJA 1R1IA 4GQLA 1QICA 1XAXA 2E2DA 2QPJA 4L6TA 3EHYA 3NX7A 3DSLA 3E8RA 1XUDA 2WOAA 3F18A 1MMPA 1SRPA 4PKVA 5D2BA 1FBLA 3KEKA 4A3WA 3UVCA 4ILWD 2Y6DA 2CKIA 1GO7P 3O64A 1OZ9A 1UMSA 1XM5A 3LJTA 3EDGA 4HMAA 3B8ZA 1JIZA 1DMTA 1GKDA 3I7GA 2OXUA 3OHOA 2ERQA 1PWUA 1ZXCA 3USNA 1GE6A 1GO8P 3KMEA 3RTTA 3Q2GA 1CQRA 1BM6A 2ERPA 3F19A 5B5PA 1XURA 1MMQA 4IJOA 2JT5A 2MZHA 2OY2A 1CGFA 2Y6CA 2X3AA 1G05A 1CGLA 5CUHA 4H1QA 4PKSA 3B2ZA 1R1JA 1CK7A 1XFVA 3HDAP 3LUMA 1UEAA 4PKUA 3TSKA 2L0RA 2O36A 4H3XA 1HTDA 1MMBA 3GBOA 5I4OA 1HFCA 1JAQA 1HV5A 1TVIA 3TS4A 1PWWA 830CA 1UTTA 2W15A 1QIAA 1EUBA 2JIHA 4DPEA 1KUKA 1D8FA 1GE7A 3EDHA 3LUNA 4H2EA 5I0LA 1EAKA 4AIGA 3Q2HA 4H76A 1UMTA 2OW9A 4GWNA 3MA2A 1BUVM 3EHXA 4GF1A 1JJ9A 1JAPA 2YB9A 1BIWA 3LIRA 2OXZA 2W13A 1GKCA 2FV5A 4ON1A 3TVCA 3EDIA 2PJTA 4G0DA 1CAQA
chains in the Genus database with same CATH topology
3AYUA 1B3DA 2Z2DA 1JANA 3U1RA 1KUHA 4L7AA 5D1SA 4PKWA 2OW1A 1O0TA 3HYGA 1IAAA 4IN9A 5BPAA 1JAOA 1AKLA 2JSDA 5JMYA 4G9LA 1OO9A 4FXYP 4XM6A 2X3BA 3HY7A 1GE5A 3DPEA 2OY4A 1IABA 3B92A 4A7BA 4JQGA 1QJIA 1CGEA 2K9CA 1IACA 5D1UA 2OI0A 1RM8A 1Q3AA 3LQBA 3KRYA 2JT6A 4JIJA 4PKTA 1SU3A 2DDFA 3DTKA 1UTZA 1K7QA 2EROA 1D7XA 2W14A 1C3IA 2DW1A 2MLSA 2DW2A 3LILA 4H84A 1D8MA 1G9KA 3RTSA 4GR8A 1GXDA 3KWVC 1ZTQA 1PWVA 3G42A 3K7LA 4XM8A 4DF9A 3N2UA 4GR3A 4R3VA 2KRJA 3ELMA 3N2VA 1A86A 3BA0A 2D1NA 2J83A 4WKEA 1BUDA 1OM7A 1BZSA 3HB2P 1BKCA 1AF0A 1G12A 5CXAA 2XS4A 456CA 1G4KA 1ROSA 4AUOA 1A85A 2AYKA 3F15A 4JP4A 2OXWA 1JK3A 1BQOA 3L0VA 3HBUP 2J0TA 3ZVSA 2MZEA 4HX3A 2X7MA 3CKIA 1KBCA 1MMRA 1SMPA 3P24A 1SLMA 1KUFA 4J4MA 1DTHA 1Y93A 1HFSA 3DPFA 1OMJA 4H82A 3F1AA 1QIBA 5L79A 1SLNA 1MNCA 4H30A 1C8TA 1KAPP 3HDBA 3K7NA 1PWPA 4XM7A 3OHLA 3DWBA 4QKZA 1OM8A 5LABA 1RMZA 3I7IA 1G49A 4WZVA 1I1IP 3DTEA 4AYKA 4XBHA 2XS3A 2DW0A 1XFWA 1CIZA 1HOVA 3TT4A 3DL1A 1C7KA 2E3XA 2OZRA 2O3EA 2X3CA 1HY7A 5I43A 4L19A 2RJPA 4FXQA 2I47A 5CZMA 4I03A 3V96B 2W12A 1Z3JA 3LKAA 3LEAA 3KMCA 2D1OA 2MLRA 3O2XA 1BKCI 1YCMA 4PKRA 1R54A 1IAEA 1R55A 2OW2A 3F17A 1AYKA 1YQYA 5B5OA 2WO9A 1OM6A 5I2ZA 2OVZA 4GR0A 4GWMA 1KUIA 3LE9A 2A8HA 1BSWA 4DD8A 1QUAA 3LJZA 1BKCE 4DV8A 1JKYA 1BQQM 1FM1A 1KUGA 3KHIA 2TCLA 1SATA 1CXVA 1YP1A 1EB6A 1IAGA 3HBVP 1YOUA 3WV3A 3DTIA 1XFXA 4JA1A 3AYKA 4JPAA 4ZR5A 3LJGA 3EWJA 4WK7A 3WV2A 1ND1A 4L63A 1I76A 1XUCA 3P1VA 1R1HA 3LIKA 3ZUKA 1ASTA 4GUYA 5D1TA 2AIGP 3LMCA 5H8XA 1K7GA 1XFUA 2OW0A 4EFSA 1ZS0A 3LQ0A 2K2GA 1OS2A 1B8YA 3AIGA 4CTHA 5BOTA 1PWQA 3LGPA 1H71P 4I35A 1Y8JA 2YIGA 4WF6A 1K7IA 5D3CA 1FLSA 1WNIA 1ATLA 3HY9A 3SHIA 4H49A 1XFZA 1IADA 3KECA 2HU6A 4WKIA 3ZXHA 2RJQA 2V4BA 1USNA 3VTGA 5BOYA 5I12A 1JIWP 1I73A 3F16A 4Q1LA 1OS9A 2SRTA 2W0DA 1S4BP 3WV1A 3KEJA 1D5JA 2DDYA 2JNPA 3G5CA 3EDZA 1ZVXA 4FU4A 4IUWA 966CA 4FVLA 1J7NA 2YUFA 3L0TA 1L6JA 4PKQA 1XFYA 2WO8A 5L7FA 2MZIA 3LK8A 1Y0VA 2OVXA 4XCTA 1ZP5A 2FV9A 2CLTA 5D7WA 3VI1A 2N8RA 5I3MA 2POJA 1JH1A 3DNGA 2USNA 4AXQA 1ZXVA 1O0QA 1QJJA 1R1IA 4GQLA 1QICA 2E2DA 2QPJA 4L6TA 3EHYA 3NX7A 3DSLA 3E8RA 1XUDA 2WOAA 3F18A 1MMPA 1SRPA 4PKVA 5D2BA 1FBLA 3KEKA 4A3WA 3UVCA 4ILWD 2Y6DA 2CKIA 1GO7P 3O64A 1UMSA 3LJTA 3EDGA 4HMAA 3B8ZA 1JIZA 1DMTA 1GKDA 3I7GA 2OXUA 3OHOA 2ERQA 1PWUA 1ZXCA 3USNA 1GE6A 1GO8P 3KMEA 3RTTA 3Q2GA 1CQRA 1BM6A 2ERPA 3F19A 5B5PA 1XURA 1MMQA 4IJOA 2JT5A 2MZHA 2OY2A 1CGFA 2Y6CA 2X3AA 1G05A 1CGLA 5CUHA 4H1QA 4PKSA 3B2ZA 1R1JA 1CK7A 1XFVA 3HDAP 3LUMA 1UEAA 4PKUA 3TSKA 2L0RA 2O36A 4H3XA 1HTDA 1MMBA 3GBOA 5I4OA 1HFCA 1JAQA 1HV5A 3TS4A 1PWWA 830CA 1UTTA 2W15A 1QIAA 1EUBA 2JIHA 4DPEA 1KUKA 1D8FA 1GE7A 3EDHA 3LUNA 4H2EA 5I0LA 1EAKA 4AIGA 3Q2HA 4H76A 1UMTA 2OW9A 4GWNA 3MA2A 1BUVM 3EHXA 4GF1A 1JJ9A 1JAPA 2YB9A 1BIWA 3LIRA 2OXZA 2W13A 1GKCA 2FV5A 4ON1A 3TVCA 3EDIA 2PJTA 4G0DA 1CAQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AYU A;  1B3D A;  2Z2D A;  1JAN A;  3U1R A;  1KUH A;  5D1S A;  4PKW A;  2OW1 A;  1O0T A;  3HYG A;  1IAA A;  4IN9 A;  5BPA A;  1JAO A;  1AKL A;  2JSD A;  5JMY A;  4G9L A;  1OO9 A;  4FXY P;  4XM6 A;  2X3B A;  3HY7 A;  1GE5 A;  3DPE A;  2OY4 A;  1IAB A;  3B92 A;  4A7B A;  4JQG A;  1QJI A;  1CGE A;  2K9C A;  1IAC A;  5D1U A;  2OI0 A;  1RM8 A;  1Q3A A;  3LQB A;  3KRY A;  2JT6 A;  4JIJ A;  4PKT A;  1SU3 A;  2DDF A;  1UTZ A;  1K7Q A;  2ERO A;  1D7X A;  2W14 A;  1C3I A;  2DW1 A;  2MLS A;  2DW2 A;  3LIL A;  4H84 A;  1D8M A;  1G9K A;  3RTS A;  4GR8 A;  1GXD A;  3KWV C;  1ZTQ A;  1PWV A;  3G42 A;  3K7L A;  4XM8 A;  4DF9 A;  3N2U A;  4GR3 A;  4R3V A;  2KRJ A;  3ELM A;  3N2V A;  1A86 A;  3BA0 A;  2D1N A;  2J83 A;  4WKE A;  1BUD A;  1OM7 A;  1BZS A;  3HB2 P;  1BKC A;  1AF0 A;  1G12 A;  5CXA A;  2XS4 A;  456C A;  1G4K A;  1ROS A;  4AUO A;  1A85 A;  2AYK A;  3F15 A;  4JP4 A;  2OXW A;  1JK3 A;  1BQO A;  3L0V A;  3HBU P;  2J0T A;  3ZVS A;  2MZE A;  4HX3 A;  2X7M A;  3CKI A;  1KBC A;  1MMR A;  1SMP A;  3P24 A;  1SLM A;  1KUF A;  4J4M A;  1DTH A;  1Y93 A;  1HFS A;  3DPF A;  1OMJ A;  4H82 A;  3F1A A;  1QIB A;  5L79 A;  1SLN A;  1MNC A;  4H30 A;  1C8T A;  1KAP P;  3HDB A;  3K7N A;  1PWP A;  4XM7 A;  3OHL A;  3DWB A;  4QKZ A;  1OM8 A;  5LAB A;  1RMZ A;  3I7I A;  1G49 A;  4WZV A;  1I1I P;  4AYK A;  4XBH A;  2XS3 A;  2DW0 A;  1XFW A;  1CIZ A;  1HOV A;  3TT4 A;  3DL1 A;  1C7K A;  2E3X A;  2OZR A;  2O3E A;  2X3C A;  1HY7 A;  5I43 A;  4L19 A;  2RJP A;  4FXQ A;  2I47 A;  5CZM A;  4I03 A;  3V96 B;  2W12 A;  1Z3J A;  3LKA A;  3LEA A;  3KMC A;  2D1O A;  2MLR A;  3O2X A;  1BKC I;  1YCM A;  4PKR A;  1R54 A;  1IAE A;  1R55 A;  2OW2 A;  3F17 A;  1AYK A;  1YQY A;  5B5O A;  2WO9 A;  1OM6 A;  5I2Z A;  2OVZ A;  4GR0 A;  4GWM A;  1KUI A;  3LE9 A;  2A8H A;  1BSW A;  4DD8 A;  1QUA A;  3LJZ A;  1BKC E;  4DV8 A;  1JKY A;  1BQQ M;  1FM1 A;  1KUG A;  3KHI A;  2TCL A;  1SAT A;  1CXV A;  1YP1 A;  1EB6 A;  1IAG A;  3HBV P;  1YOU A;  3WV3 A;  1XFX A;  4JA1 A;  3AYK A;  4JPA A;  4ZR5 A;  3LJG A;  3EWJ A;  4WK7 A;  3WV2 A;  1ND1 A;  4L63 A;  1I76 A;  1XUC A;  3P1V A;  1R1H A;  3LIK A;  3ZUK A;  1AST A;  4GUY A;  5D1T A;  2AIG P;  3LMC A;  5H8X A;  1K7G A;  1XFU A;  2OW0 A;  4EFS A;  1ZS0 A;  3LQ0 A;  2K2G A;  1OS2 A;  1B8Y A;  3AIG A;  4CTH A;  5BOT A;  1PWQ A;  3LGP A;  1H71 P;  4I35 A;  1Y8J A;  2YIG A;  4WF6 A;  1K7I A;  5D3C A;  1FLS A;  1WNI A;  1ATL A;  3HY9 A;  3SHI A;  4H49 A;  1XFZ A;  1IAD A;  3KEC A;  2HU6 A;  4WKI A;  3ZXH A;  2RJQ A;  2V4B A;  1USN A;  3VTG A;  5BOY A;  5I12 A;  1JIW P;  1I73 A;  3F16 A;  4Q1L A;  1OS9 A;  2SRT A;  2W0D A;  1S4B P;  3WV1 A;  3KEJ A;  1D5J A;  2DDY A;  2JNP A;  3G5C A;  3EDZ A;  1ZVX A;  4FU4 A;  4IUW A;  966C A;  4FVL A;  1J7N A;  3L0T A;  1L6J A;  4PKQ A;  1XFY A;  2WO8 A;  5L7F A;  2MZI A;  3LK8 A;  1Y0V A;  2OVX A;  4XCT A;  1ZP5 A;  2FV9 A;  2CLT A;  5D7W A;  3VI1 A;  2N8R A;  5I3M A;  2POJ A;  1JH1 A;  3DNG A;  2USN A;  4AXQ A;  1ZXV A;  1O0Q A;  1QJJ A;  1R1I A;  4GQL A;  1QIC A;  2E2D A;  2QPJ A;  4L6T A;  3EHY A;  3NX7 A;  3DSL A;  3E8R A;  1XUD A;  2WOA A;  3F18 A;  1MMP A;  1SRP A;  4PKV A;  5D2B A;  1FBL A;  3KEK A;  4A3W A;  3UVC A;  4ILW D;  2Y6D A;  2CKI A;  1GO7 P;  3O64 A;  1UMS A;  3LJT A;  3EDG A;  4HMA A;  3B8Z A;  1JIZ A;  1DMT A;  1GKD A;  3I7G A;  2OXU A;  3OHO A;  2ERQ A;  1PWU A;  1ZXC A;  3USN A;  1GE6 A;  1GO8 P;  3KME A;  3RTT A;  3Q2G A;  1CQR A;  1BM6 A;  2ERP A;  3F19 A;  5B5P A;  1XUR A;  1MMQ A;  4IJO A;  2JT5 A;  2MZH A;  2OY2 A;  1CGF A;  2Y6C A;  2X3A A;  1G05 A;  1CGL A;  5CUH A;  4H1Q A;  4PKS A;  3B2Z A;  1R1J A;  1CK7 A;  1XFV A;  3HDA P;  3LUM A;  1UEA A;  4PKU A;  3TSK A;  2L0R A;  2O36 A;  4H3X A;  1HTD A;  1MMB A;  3GBO A;  5I4O A;  1HFC A;  1JAQ A;  1HV5 A;  3TS4 A;  1PWW A;  830C A;  1UTT A;  2W15 A;  1QIA A;  1EUB A;  2JIH A;  4DPE A;  1KUK A;  1D8F A;  1GE7 A;  3EDH A;  3LUN A;  4H2E A;  5I0L A;  1EAK A;  4AIG A;  3Q2H A;  4H76 A;  1UMT A;  2OW9 A;  4GWN A;  3MA2 A;  1BUV M;  3EHX A;  4GF1 A;  1JJ9 A;  1JAP A;  2YB9 A;  1BIW A;  3LIR A;  2OXZ A;  2W13 A;  1GKC A;  2FV5 A;  4ON1 A;  3TVC A;  3EDI A;  2PJT A;  4G0D A;  1CAQ A; 
#chains in the Genus database with same CATH topology
 3AYU A;  1B3D A;  2Z2D A;  1JAN A;  3U1R A;  1KUH A;  4L7A A;  5D1S A;  4PKW A;  2OW1 A;  1O0T A;  3HYG A;  1IAA A;  4IN9 A;  5BPA A;  1JAO A;  1AKL A;  2JSD A;  5JMY A;  4G9L A;  1OO9 A;  4FXY P;  4XM6 A;  2X3B A;  3HY7 A;  1GE5 A;  3DPE A;  2OY4 A;  1IAB A;  3B92 A;  4A7B A;  4JQG A;  1QJI A;  1CGE A;  2K9C A;  1IAC A;  5D1U A;  2OI0 A;  1RM8 A;  1Q3A A;  3LQB A;  3KRY A;  2JT6 A;  4JIJ A;  4PKT A;  1SU3 A;  2DDF A;  3DTK A;  1UTZ A;  1K7Q A;  2ERO A;  1D7X A;  2W14 A;  1C3I A;  2DW1 A;  2MLS A;  2DW2 A;  3LIL A;  4H84 A;  1D8M A;  1G9K A;  3RTS A;  4GR8 A;  1GXD A;  3KWV C;  1ZTQ A;  1PWV A;  3G42 A;  3K7L A;  4XM8 A;  4DF9 A;  3N2U A;  4GR3 A;  4R3V A;  2KRJ A;  3ELM A;  3N2V A;  1A86 A;  3BA0 A;  2D1N A;  2J83 A;  4WKE A;  1BUD A;  1OM7 A;  1BZS A;  3HB2 P;  1BKC A;  1AF0 A;  1G12 A;  5CXA A;  2XS4 A;  456C A;  1G4K A;  1ROS A;  4AUO A;  1A85 A;  2AYK A;  3F15 A;  4JP4 A;  2OXW A;  1JK3 A;  1BQO A;  3L0V A;  3HBU P;  2J0T A;  3ZVS A;  2MZE A;  4HX3 A;  2X7M A;  3CKI A;  1KBC A;  1MMR A;  1SMP A;  3P24 A;  1SLM A;  1KUF A;  4J4M A;  1DTH A;  1Y93 A;  1HFS A;  3DPF A;  1OMJ A;  4H82 A;  3F1A A;  1QIB A;  5L79 A;  1SLN A;  1MNC A;  4H30 A;  1C8T A;  1KAP P;  3HDB A;  3K7N A;  1PWP A;  4XM7 A;  3OHL A;  3DWB A;  4QKZ A;  1OM8 A;  5LAB A;  1RMZ A;  3I7I A;  1G49 A;  4WZV A;  1I1I P;  3DTE A;  4AYK A;  4XBH A;  2XS3 A;  2DW0 A;  1XFW A;  1CIZ A;  1HOV A;  3TT4 A;  3DL1 A;  1C7K A;  2E3X A;  2OZR A;  2O3E A;  2X3C A;  1HY7 A;  5I43 A;  4L19 A;  2RJP A;  4FXQ A;  2I47 A;  5CZM A;  4I03 A;  3V96 B;  2W12 A;  1Z3J A;  3LKA A;  3LEA A;  3KMC A;  2D1O A;  2MLR A;  3O2X A;  1BKC I;  1YCM A;  4PKR A;  1R54 A;  1IAE A;  1R55 A;  2OW2 A;  3F17 A;  1AYK A;  1YQY A;  5B5O A;  2WO9 A;  1OM6 A;  5I2Z A;  2OVZ A;  4GR0 A;  4GWM A;  1KUI A;  3LE9 A;  2A8H A;  1BSW A;  4DD8 A;  1QUA A;  3LJZ A;  1BKC E;  4DV8 A;  1JKY A;  1BQQ M;  1FM1 A;  1KUG A;  3KHI A;  2TCL A;  1SAT A;  1CXV A;  1YP1 A;  1EB6 A;  1IAG A;  3HBV P;  1YOU A;  3WV3 A;  3DTI A;  1XFX A;  4JA1 A;  3AYK A;  4JPA A;  4ZR5 A;  3LJG A;  3EWJ A;  4WK7 A;  3WV2 A;  1ND1 A;  4L63 A;  1I76 A;  1XUC A;  3P1V A;  1R1H A;  3LIK A;  3ZUK A;  1AST A;  4GUY A;  5D1T A;  2AIG P;  3LMC A;  5H8X A;  1K7G A;  1XFU A;  2OW0 A;  4EFS A;  1ZS0 A;  3LQ0 A;  2K2G A;  1OS2 A;  1B8Y A;  3AIG A;  4CTH A;  5BOT A;  1PWQ A;  3LGP A;  1H71 P;  4I35 A;  1Y8J A;  2YIG A;  4WF6 A;  1K7I A;  5D3C A;  1FLS A;  1WNI A;  1ATL A;  3HY9 A;  3SHI A;  4H49 A;  1XFZ A;  1IAD A;  3KEC A;  2HU6 A;  4WKI A;  3ZXH A;  2RJQ A;  2V4B A;  1USN A;  3VTG A;  5BOY A;  5I12 A;  1JIW P;  1I73 A;  3F16 A;  4Q1L A;  1OS9 A;  2SRT A;  2W0D A;  1S4B P;  3WV1 A;  3KEJ A;  1D5J A;  2DDY A;  2JNP A;  3G5C A;  3EDZ A;  1ZVX A;  4FU4 A;  4IUW A;  966C A;  4FVL A;  1J7N A;  2YUF A;  3L0T A;  1L6J A;  4PKQ A;  1XFY A;  2WO8 A;  5L7F A;  2MZI A;  3LK8 A;  1Y0V A;  2OVX A;  4XCT A;  1ZP5 A;  2FV9 A;  2CLT A;  5D7W A;  3VI1 A;  2N8R A;  5I3M A;  2POJ A;  1JH1 A;  3DNG A;  2USN A;  4AXQ A;  1ZXV A;  1O0Q A;  1QJJ A;  1R1I A;  4GQL A;  1QIC A;  1XAX A;  2E2D A;  2QPJ A;  4L6T A;  3EHY A;  3NX7 A;  3DSL A;  3E8R A;  1XUD A;  2WOA A;  3F18 A;  1MMP A;  1SRP A;  4PKV A;  5D2B A;  1FBL A;  3KEK A;  4A3W A;  3UVC A;  4ILW D;  2Y6D A;  2CKI A;  1GO7 P;  3O64 A;  1OZ9 A;  1UMS A;  1XM5 A;  3LJT A;  3EDG A;  4HMA A;  3B8Z A;  1JIZ A;  1DMT A;  1GKD A;  3I7G A;  2OXU A;  3OHO A;  2ERQ A;  1PWU A;  1ZXC A;  3USN A;  1GE6 A;  1GO8 P;  3KME A;  3RTT A;  3Q2G A;  1CQR A;  1BM6 A;  2ERP A;  3F19 A;  5B5P A;  1XUR A;  1MMQ A;  4IJO A;  2JT5 A;  2MZH A;  2OY2 A;  1CGF A;  2Y6C A;  2X3A A;  1G05 A;  1CGL A;  5CUH A;  4H1Q A;  4PKS A;  3B2Z A;  1R1J A;  1CK7 A;  1XFV A;  3HDA P;  3LUM A;  1UEA A;  4PKU A;  3TSK A;  2L0R A;  2O36 A;  4H3X A;  1HTD A;  1MMB A;  3GBO A;  5I4O A;  1HFC A;  1JAQ A;  1HV5 A;  1TVI A;  3TS4 A;  1PWW A;  830C A;  1UTT A;  2W15 A;  1QIA A;  1EUB A;  2JIH A;  4DPE A;  1KUK A;  1D8F A;  1GE7 A;  3EDH A;  3LUN A;  4H2E A;  5I0L A;  1EAK A;  4AIG A;  3Q2H A;  4H76 A;  1UMT A;  2OW9 A;  4GWN A;  3MA2 A;  1BUV M;  3EHX A;  4GF1 A;  1JJ9 A;  1JAP A;  2YB9 A;  1BIW A;  3LIR A;  2OXZ A;  2W13 A;  1GKC A;  2FV5 A;  4ON1 A;  3TVC A;  3EDI A;  2PJT A;  4G0D A;  1CAQ A; 
#chains in the Genus database with same CATH homology
 3AYU A;  1B3D A;  2Z2D A;  1JAN A;  3U1R A;  1KUH A;  4L7A A;  5D1S A;  4PKW A;  2OW1 A;  1O0T A;  3HYG A;  1IAA A;  4IN9 A;  5BPA A;  1JAO A;  1AKL A;  2JSD A;  5JMY A;  4G9L A;  1OO9 A;  4FXY P;  4XM6 A;  2X3B A;  3HY7 A;  1GE5 A;  3DPE A;  2OY4 A;  1IAB A;  3B92 A;  4A7B A;  4JQG A;  1QJI A;  1CGE A;  2K9C A;  1IAC A;  5D1U A;  2OI0 A;  1RM8 A;  1Q3A A;  3LQB A;  3KRY A;  2JT6 A;  4JIJ A;  4PKT A;  1SU3 A;  2DDF A;  3DTK A;  1UTZ A;  1K7Q A;  2ERO A;  1D7X A;  2W14 A;  1C3I A;  2DW1 A;  2MLS A;  2DW2 A;  3LIL A;  4H84 A;  1D8M A;  1G9K A;  3RTS A;  4GR8 A;  1GXD A;  3KWV C;  1ZTQ A;  1PWV A;  3G42 A;  3K7L A;  4XM8 A;  4DF9 A;  3N2U A;  4GR3 A;  4R3V A;  2KRJ A;  3ELM A;  3N2V A;  1A86 A;  3BA0 A;  2D1N A;  2J83 A;  4WKE A;  1BUD A;  1OM7 A;  1BZS A;  3HB2 P;  1BKC A;  1AF0 A;  1G12 A;  5CXA A;  2XS4 A;  456C A;  1G4K A;  1ROS A;  4AUO A;  1A85 A;  2AYK A;  3F15 A;  4JP4 A;  2OXW A;  1JK3 A;  1BQO A;  3L0V A;  3HBU P;  2J0T A;  3ZVS A;  2MZE A;  4HX3 A;  2X7M A;  3CKI A;  1KBC A;  1MMR A;  1SMP A;  3P24 A;  1SLM A;  1KUF A;  4J4M A;  1DTH A;  1Y93 A;  1HFS A;  3DPF A;  1OMJ A;  4H82 A;  3F1A A;  1QIB A;  5L79 A;  1SLN A;  1MNC A;  4H30 A;  1C8T A;  1KAP P;  3HDB A;  3K7N A;  1PWP A;  4XM7 A;  3OHL A;  3DWB A;  4QKZ A;  1OM8 A;  5LAB A;  1RMZ A;  3I7I A;  1G49 A;  4WZV A;  1I1I P;  3DTE A;  4AYK A;  4XBH A;  2XS3 A;  2DW0 A;  1XFW A;  1CIZ A;  1HOV A;  3TT4 A;  3DL1 A;  1C7K A;  2E3X A;  2OZR A;  2O3E A;  2X3C A;  1HY7 A;  5I43 A;  4L19 A;  2RJP A;  4FXQ A;  2I47 A;  5CZM A;  4I03 A;  3V96 B;  2W12 A;  1Z3J A;  3LKA A;  3LEA A;  3KMC A;  2D1O A;  2MLR A;  3O2X A;  1BKC I;  1YCM A;  4PKR A;  1R54 A;  1IAE A;  1R55 A;  2OW2 A;  3F17 A;  1AYK A;  1YQY A;  5B5O A;  2WO9 A;  1OM6 A;  5I2Z A;  2OVZ A;  4GR0 A;  4GWM A;  1KUI A;  3LE9 A;  2A8H A;  1BSW A;  4DD8 A;  1QUA A;  3LJZ A;  1BKC E;  4DV8 A;  1JKY A;  1BQQ M;  1FM1 A;  1KUG A;  3KHI A;  2TCL A;  1SAT A;  1CXV A;  1YP1 A;  1EB6 A;  1IAG A;  3HBV P;  1YOU A;  3WV3 A;  3DTI A;  1XFX A;  4JA1 A;  3AYK A;  4JPA A;  4ZR5 A;  3LJG A;  3EWJ A;  4WK7 A;  3WV2 A;  1ND1 A;  4L63 A;  1I76 A;  1XUC A;  3P1V A;  1R1H A;  3LIK A;  3ZUK A;  1AST A;  4GUY A;  5D1T A;  2AIG P;  3LMC A;  5H8X A;  1K7G A;  1XFU A;  2OW0 A;  4EFS A;  1ZS0 A;  3LQ0 A;  2K2G A;  1OS2 A;  1B8Y A;  3AIG A;  4CTH A;  5BOT A;  1PWQ A;  3LGP A;  1H71 P;  4I35 A;  1Y8J A;  2YIG A;  4WF6 A;  1K7I A;  5D3C A;  1FLS A;  1WNI A;  1ATL A;  3HY9 A;  3SHI A;  4H49 A;  1XFZ A;  1IAD A;  3KEC A;  2HU6 A;  4WKI A;  3ZXH A;  2RJQ A;  2V4B A;  1USN A;  3VTG A;  5BOY A;  5I12 A;  1JIW P;  1I73 A;  3F16 A;  4Q1L A;  1OS9 A;  2SRT A;  2W0D A;  1S4B P;  3WV1 A;  3KEJ A;  1D5J A;  2DDY A;  2JNP A;  3G5C A;  3EDZ A;  1ZVX A;  4FU4 A;  4IUW A;  966C A;  4FVL A;  1J7N A;  2YUF A;  3L0T A;  1L6J A;  4PKQ A;  1XFY A;  2WO8 A;  5L7F A;  2MZI A;  3LK8 A;  1Y0V A;  2OVX A;  4XCT A;  1ZP5 A;  2FV9 A;  2CLT A;  5D7W A;  3VI1 A;  2N8R A;  5I3M A;  2POJ A;  1JH1 A;  3DNG A;  2USN A;  4AXQ A;  1ZXV A;  1O0Q A;  1QJJ A;  1R1I A;  4GQL A;  1QIC A;  2E2D A;  2QPJ A;  4L6T A;  3EHY A;  3NX7 A;  3DSL A;  3E8R A;  1XUD A;  2WOA A;  3F18 A;  1MMP A;  1SRP A;  4PKV A;  5D2B A;  1FBL A;  3KEK A;  4A3W A;  3UVC A;  4ILW D;  2Y6D A;  2CKI A;  1GO7 P;  3O64 A;  1UMS A;  3LJT A;  3EDG A;  4HMA A;  3B8Z A;  1JIZ A;  1DMT A;  1GKD A;  3I7G A;  2OXU A;  3OHO A;  2ERQ A;  1PWU A;  1ZXC A;  3USN A;  1GE6 A;  1GO8 P;  3KME A;  3RTT A;  3Q2G A;  1CQR A;  1BM6 A;  2ERP A;  3F19 A;  5B5P A;  1XUR A;  1MMQ A;  4IJO A;  2JT5 A;  2MZH A;  2OY2 A;  1CGF A;  2Y6C A;  2X3A A;  1G05 A;  1CGL A;  5CUH A;  4H1Q A;  4PKS A;  3B2Z A;  1R1J A;  1CK7 A;  1XFV A;  3HDA P;  3LUM A;  1UEA A;  4PKU A;  3TSK A;  2L0R A;  2O36 A;  4H3X A;  1HTD A;  1MMB A;  3GBO A;  5I4O A;  1HFC A;  1JAQ A;  1HV5 A;  3TS4 A;  1PWW A;  830C A;  1UTT A;  2W15 A;  1QIA A;  1EUB A;  2JIH A;  4DPE A;  1KUK A;  1D8F A;  1GE7 A;  3EDH A;  3LUN A;  4H2E A;  5I0L A;  1EAK A;  4AIG A;  3Q2H A;  4H76 A;  1UMT A;  2OW9 A;  4GWN A;  3MA2 A;  1BUV M;  3EHX A;  4GF1 A;  1JJ9 A;  1JAP A;  2YB9 A;  1BIW A;  3LIR A;  2OXZ A;  2W13 A;  1GKC A;  2FV5 A;  4ON1 A;  3TVC A;  3EDI A;  2PJT A;  4G0D A;  1CAQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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