1ROSA

Crystal structure of mmp-12 complexed to 2-(1,3-dioxo-1,3-dihydro-2h-isoindol-2-yl)ethyl-4-(4-ethoxy[1,1-biphenyl]-4-yl)-4-oxobutanoic acid
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
159
structure length
159
Chain Sequence
GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDFHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYGD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of novel non-peptidic, non-zinc chelating inhibitors bound to MMP-12.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Macrophage metalloelastase
total genus 43
structure length 159
sequence length 159
chains with identical sequence B
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2003-12-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 1rosA00
1R1HA 1JK3A 3OHLA 2JNPA 4FXYP 3LILA 3HBVP 1CIZA 2XS3A 3LEAA 1BQQM 3LGPA 3KWVC 1JANA 2CKIA 3EHXA 2O36A 4DF9A 3KEJA 5D3CA 4DPEA 1G05A 2SRTA 1K7QA 2V4BA 3SHIA 1MMBA 1QUAA 3EDGA 1O0QA 2OVZA 1A86A 5L7FA 1SLNA 2X3CA 1SLMA 1GE6A 5I2ZA 1YOUA 1CGEA 4GUYA 1SMPA 1OM7A 3KHIA 4R3VA 3EDZA 1R55A 1BSWA 3N2UA 1A85A 3K7NA 3ZUKA 1IABA 1IACA 1BKCA 1IAGA 1ZXVA 3DNGA 4WF6A 2MLRA 2FV5A 3DSLA 4WK7A 1UTTA 2OY2A 2DW0A 4J4MA 1OM8A 1SU3A 2JT6A 3AIGA 1HTDA 2HU6A 1D8MA 4DD8A 1C8TA 1UEAA 2OW1A 4G9LA 1CXVA 1EAKA 2PJTA 4ZR5A 4G0DA 3B92A 1GE5A 4PKTA 1PWVA 4H3XA 2W0DA 3ZXHA 2J83A 3G42A 5L79A 3F1AA 2X7MA 3TSKA 2L0RA 4HMAA 4L63A 1D8FA 1IADA 1GKCA 1QJIA 4XM8A 3LK8A 1OS9A 1C3IA 5BPAA 4H84A 2J0TA 5B5OA 2WO8A 2USNA 3HDAP 1FM1A 1G12A 2FV9A 3KEKA 3KECA 1OMJA 1JAPA 3AYUA 3E8RA 1CAQA 2YB9A 3HBUP 4PKQA 1FLSA 3EDHA 3NX7A 4A3WA 4ON1A 2A8HA 4QKZA 1Y8JA 2DW2A 1CK7A 2OY4A 3UVCA 2WO9A 4EFSA 2AYKA 2DDYA 1AYKA 1BZSA 2MZHA 3LIRA 5D2BA 1Q3AA 1ASTA 1Z3JA 4WKIA 3TT4A 1GXDA 4WKEA 1XFWA 3LJTA 1H71P 1OM6A 3F16A 2POJA 5D7WA 1IAAA 1BKCI 3AYKA 1B8YA 2ERPA 4JP4A 3LUMA 1SATA 3LQ0A 4JIJA 1EUBA 5LABA 3N2VA 2W14A 1MMQA 4IN9A 4JQGA 3VTGA 3L0VA 3KMCA 1C7KA 1R1JA 1JJ9A 2OXZA 1K7GA 3BA0A 3HDBA 2WOAA 1ATLA 1MMPA 1WNIA 3K7LA 4JPAA 1JIWP 3O64A 2E2DA 4L19A 1JAOA 2OW9A 4PKSA 2W15A 1G4KA 1HV5A 2DDFA 1AF0A 1KUFA 2JT5A 5D1UA 1JH1A 2OI0A 2K2GA 1JKYA 1GO7P 966CA 1QICA 5CXAA 4A7BA 1HOVA 3F17A 1KUGA 3ELMA 4PKVA 1B3DA 1JAQA 1OS2A 2DW1A 1GE7A 4GR8A 4WZVA 5CZMA 3LKAA 1HY7A 3DPFA 4FU4A 3MA2A 1BKCE 3TS4A 1KUIA 1K7IA 5I4OA 2KRJA 4XCTA 1S4BP 1QIBA 3O2XA 2Y6DA 1XURA 4H49A 2YIGA 1MNCA 2CLTA 1J7NA 2N8RA 1KBCA 3L0TA 1L6JA 3B8ZA 1QJJA 1Y0VA 1GKDA 4FXQA 5JMYA 3LMCA 830CA 5D1SA 3RTTA 1ZXCA 2OW2A 1BM6A 4PKUA 2RJPA 2MZIA 4H1QA 4JA1A 1PWQA 2D1OA 2OW0A 2AIGP 1O0TA 4PKRA 1D7XA 3CKIA 2W12A 3F19A 3HY9A 4GR0A 1UMSA 1ZS0A 1I73A 1OO9A 2OXUA 3F18A 1PWWA 2JSDA 1GO8P 1PWPA 2MZEA 2QPJA 1XUDA 4AXQA 5D1TA 1UTZA 4PKWA 1IAEA 2E3XA 1FBLA 1UMTA 3TVCA 1ZVXA 4Q1LA 1HFSA 1R1IA 2X3AA 1BIWA 2O3EA 3LIKA 1XUCA 2I47A 2ERQA 1USNA 3I7IA 2D1NA 4XM6A 5CUHA 3HB2P 3WV3A 3VI1A 1ND1A 2RJQA 1YCMA 4GF1A 3P1VA 3RTSA 1I1IP 3ZVSA 2XS4A 1XFXA 4I35A 2W13A 3OHOA 4I03A 2X3BA 1XFVA 5I43A 5H8XA 3U1RA 3KMEA 3P24A 1CQRA 3LQBA 1HFCA 3DWBA 4ILWD 2K9CA 1KUHA 3LJZA 4FVLA 4H2EA 1EB6A 1YP1A 5B5PA 4IJOA 4GWMA 456CA 2TCLA 1BQOA 4HX3A 2OXWA 5I0LA 3HY7A 1DTHA 3DPEA 4L6TA 1ZTQA 2Z2DA 4AYKA 2MLSA 2Y6CA 3V96B 4IUWA 1XFYA 1XFUA 4AIGA 1Y93A 1DMTA 3LJGA 1RM8A 3WV2A 1BUVM 1BUDA 3I7GA 1I76A 2OVXA 4GWNA 4H30A 2JIHA 4DV8A 2OZRA 3WV1A 1CGFA 3F15A 3LE9A 3B2ZA 3EWJA 2EROA 3EDIA 3GBOA 3KRYA 5BOYA 4XBHA 5I3MA 3LUNA 3G5CA 1MMRA 4GQLA 1CGLA 1JIZA 1ROSA 3EHYA 4AUOA 3USNA 1SRPA 1QIAA 3Q2GA 4CTHA 3DL1A 4H82A 5BOTA 1KAPP 1ZP5A 1KUKA 3HYGA 1RMZA 4H76A 5I12A 1XFZA 4XM7A 1PWUA 4GR3A 1G9KA 1D5JA 1YQYA 1AKLA 1G49A 1R54A 3Q2HA
chains in the Genus database with same CATH superfamily
1R1HA 1JK3A 3OHLA 2JNPA 4FXYP 3LILA 3HBVP 1CIZA 2XS3A 3LEAA 1BQQM 3LGPA 3KWVC 1JANA 2CKIA 3EHXA 2O36A 4DF9A 3KEJA 5D3CA 4DPEA 1G05A 2SRTA 1K7QA 2V4BA 3SHIA 1MMBA 1QUAA 3EDGA 1O0QA 2OVZA 1A86A 3DTKA 5L7FA 1SLNA 2X3CA 1SLMA 1GE6A 5I2ZA 1YOUA 1CGEA 4GUYA 1SMPA 1OM7A 3KHIA 4R3VA 3EDZA 1R55A 1BSWA 3N2UA 1A85A 3K7NA 3ZUKA 1IABA 1IACA 1BKCA 1IAGA 1ZXVA 3DNGA 4WF6A 2MLRA 2FV5A 3DSLA 4WK7A 1UTTA 2OY2A 2DW0A 4J4MA 1OM8A 1SU3A 2JT6A 3AIGA 1HTDA 2HU6A 1D8MA 4DD8A 1C8TA 1UEAA 2OW1A 4G9LA 1CXVA 1EAKA 2PJTA 4ZR5A 4G0DA 3B92A 1GE5A 4PKTA 1PWVA 4H3XA 2W0DA 3ZXHA 2J83A 3G42A 5L79A 3F1AA 1TVIA 2X7MA 3TSKA 2L0RA 4HMAA 4L63A 1D8FA 1IADA 1GKCA 1QJIA 4L7AA 4XM8A 3LK8A 1OS9A 1C3IA 5BPAA 4H84A 2J0TA 5B5OA 2WO8A 2USNA 3HDAP 1FM1A 1G12A 2FV9A 3KEKA 3KECA 1OMJA 1JAPA 3AYUA 3E8RA 1XAXA 1CAQA 2YB9A 3HBUP 4PKQA 1FLSA 3EDHA 3NX7A 4A3WA 4ON1A 2A8HA 4QKZA 1Y8JA 2DW2A 1CK7A 2OY4A 3UVCA 2WO9A 4EFSA 2AYKA 2DDYA 1AYKA 1BZSA 2MZHA 3LIRA 5D2BA 1Q3AA 1ASTA 1Z3JA 4WKIA 3TT4A 1GXDA 4WKEA 1XFWA 3LJTA 1H71P 1OM6A 3F16A 2POJA 5D7WA 1IAAA 1BKCI 3AYKA 1B8YA 2ERPA 4JP4A 3LUMA 1SATA 3LQ0A 4JIJA 1EUBA 5LABA 3N2VA 2W14A 1MMQA 4IN9A 4JQGA 3VTGA 3L0VA 3KMCA 1C7KA 3DTEA 1R1JA 1JJ9A 2OXZA 1K7GA 3BA0A 3HDBA 2WOAA 1ATLA 1MMPA 1WNIA 3K7LA 4JPAA 1JIWP 3O64A 2E2DA 4L19A 1JAOA 2OW9A 4PKSA 2W15A 1G4KA 1HV5A 2DDFA 1AF0A 1KUFA 2JT5A 5D1UA 1JH1A 2OI0A 2K2GA 1JKYA 1GO7P 966CA 1QICA 5CXAA 4A7BA 1HOVA 3F17A 1KUGA 3ELMA 4PKVA 1B3DA 1JAQA 1OS2A 2DW1A 1GE7A 4GR8A 4WZVA 5CZMA 3LKAA 1HY7A 3DPFA 4FU4A 3MA2A 1BKCE 3TS4A 1KUIA 1K7IA 5I4OA 2KRJA 4XCTA 1S4BP 1QIBA 3O2XA 2Y6DA 1XURA 4H49A 2YIGA 1MNCA 2CLTA 1J7NA 2N8RA 1KBCA 3L0TA 1L6JA 3B8ZA 1QJJA 1Y0VA 1GKDA 4FXQA 5JMYA 3LMCA 830CA 5D1SA 3RTTA 1ZXCA 2OW2A 1BM6A 4PKUA 2RJPA 2MZIA 4H1QA 4JA1A 1PWQA 2D1OA 2OW0A 2AIGP 1O0TA 4PKRA 1D7XA 3CKIA 2W12A 3F19A 3HY9A 4GR0A 1UMSA 1ZS0A 1I73A 1OO9A 2OXUA 3F18A 1PWWA 2JSDA 1GO8P 1PWPA 2MZEA 2QPJA 1XUDA 4AXQA 5D1TA 2YUFA 1UTZA 4PKWA 1IAEA 2E3XA 1FBLA 1UMTA 3TVCA 1ZVXA 4Q1LA 1HFSA 1R1IA 2X3AA 1BIWA 2O3EA 3LIKA 1XUCA 2I47A 2ERQA 1USNA 3I7IA 2D1NA 4XM6A 5CUHA 3HB2P 3WV3A 3VI1A 1ND1A 2RJQA 1YCMA 4GF1A 3P1VA 3RTSA 1I1IP 3ZVSA 2XS4A 1XFXA 4I35A 2W13A 3OHOA 4I03A 2X3BA 1XFVA 5I43A 5H8XA 3U1RA 3KMEA 3P24A 1CQRA 3LQBA 1HFCA 3DWBA 4ILWD 2K9CA 1KUHA 3LJZA 4FVLA 4H2EA 1EB6A 1YP1A 5B5PA 4IJOA 4GWMA 456CA 2TCLA 1BQOA 4HX3A 2OXWA 5I0LA 3HY7A 1DTHA 3DPEA 4L6TA 1ZTQA 2Z2DA 4AYKA 2MLSA 2Y6CA 3V96B 4IUWA 1XFYA 1XFUA 4AIGA 1Y93A 1DMTA 3LJGA 1RM8A 3WV2A 1BUVM 1BUDA 3I7GA 1I76A 2OVXA 4GWNA 1OZ9A 4H30A 2JIHA 4DV8A 2OZRA 3WV1A 1CGFA 3F15A 3LE9A 3B2ZA 3DTIA 3EWJA 2EROA 3EDIA 3GBOA 3KRYA 5BOYA 4XBHA 5I3MA 3LUNA 3G5CA 1MMRA 4GQLA 1CGLA 1XM5A 1JIZA 1ROSA 3EHYA 4AUOA 3USNA 1SRPA 1QIAA 3Q2GA 4CTHA 3DL1A 4H82A 5BOTA 1KAPP 1ZP5A 1KUKA 3HYGA 1RMZA 4H76A 5I12A 1XFZA 4XM7A 1PWUA 4GR3A 1G9KA 1D5JA 1YQYA 1AKLA 1G49A 1R54A 3Q2HA
chains in the Genus database with same CATH topology
1R1HA 1JK3A 3OHLA 2JNPA 4FXYP 3LILA 3HBVP 1CIZA 2XS3A 3LEAA 1BQQM 3LGPA 3KWVC 1JANA 2CKIA 3EHXA 2O36A 4DF9A 3KEJA 5D3CA 4DPEA 1G05A 2SRTA 1K7QA 2V4BA 3SHIA 1MMBA 1QUAA 3EDGA 1O0QA 2OVZA 1A86A 3DTKA 5L7FA 1SLNA 2X3CA 1SLMA 1GE6A 5I2ZA 1YOUA 1CGEA 4GUYA 1SMPA 1OM7A 3KHIA 4R3VA 3EDZA 1R55A 1BSWA 3N2UA 1A85A 3K7NA 3ZUKA 1IABA 1IACA 1BKCA 1IAGA 1ZXVA 3DNGA 4WF6A 2MLRA 2FV5A 3DSLA 4WK7A 1UTTA 2OY2A 2DW0A 4J4MA 1OM8A 1SU3A 2JT6A 3AIGA 1HTDA 2HU6A 1D8MA 4DD8A 1C8TA 1UEAA 2OW1A 4G9LA 1CXVA 1EAKA 2PJTA 4ZR5A 4G0DA 3B92A 1GE5A 4PKTA 1PWVA 4H3XA 2W0DA 3ZXHA 2J83A 3G42A 5L79A 3F1AA 2X7MA 3TSKA 2L0RA 4HMAA 4L63A 1D8FA 1IADA 1GKCA 1QJIA 4L7AA 4XM8A 3LK8A 1OS9A 1C3IA 5BPAA 4H84A 2J0TA 5B5OA 2WO8A 2USNA 3HDAP 1FM1A 1G12A 2FV9A 3KEKA 3KECA 1OMJA 1JAPA 3AYUA 3E8RA 1CAQA 2YB9A 3HBUP 4PKQA 1FLSA 3EDHA 3NX7A 4A3WA 4ON1A 2A8HA 4QKZA 1Y8JA 2DW2A 1CK7A 2OY4A 3UVCA 2WO9A 4EFSA 2AYKA 2DDYA 1AYKA 1BZSA 2MZHA 3LIRA 5D2BA 1Q3AA 1ASTA 1Z3JA 4WKIA 3TT4A 1GXDA 4WKEA 1XFWA 3LJTA 1H71P 1OM6A 3F16A 2POJA 5D7WA 1IAAA 1BKCI 3AYKA 1B8YA 2ERPA 4JP4A 3LUMA 1SATA 3LQ0A 4JIJA 1EUBA 5LABA 3N2VA 2W14A 1MMQA 4IN9A 4JQGA 3VTGA 3L0VA 3KMCA 1C7KA 3DTEA 1R1JA 1JJ9A 2OXZA 1K7GA 3BA0A 3HDBA 2WOAA 1ATLA 1MMPA 1WNIA 3K7LA 4JPAA 1JIWP 3O64A 2E2DA 4L19A 1JAOA 2OW9A 4PKSA 2W15A 1G4KA 1HV5A 2DDFA 1AF0A 1KUFA 2JT5A 5D1UA 1JH1A 2OI0A 2K2GA 1JKYA 1GO7P 966CA 1QICA 5CXAA 4A7BA 1HOVA 3F17A 1KUGA 3ELMA 4PKVA 1B3DA 1JAQA 1OS2A 2DW1A 1GE7A 4GR8A 4WZVA 5CZMA 3LKAA 1HY7A 3DPFA 4FU4A 3MA2A 1BKCE 3TS4A 1KUIA 1K7IA 5I4OA 2KRJA 4XCTA 1S4BP 1QIBA 3O2XA 2Y6DA 1XURA 4H49A 2YIGA 1MNCA 2CLTA 1J7NA 2N8RA 1KBCA 3L0TA 1L6JA 3B8ZA 1QJJA 1Y0VA 1GKDA 4FXQA 5JMYA 3LMCA 830CA 5D1SA 3RTTA 1ZXCA 2OW2A 1BM6A 4PKUA 2RJPA 2MZIA 4H1QA 4JA1A 1PWQA 2D1OA 2OW0A 2AIGP 1O0TA 4PKRA 1D7XA 3CKIA 2W12A 3F19A 3HY9A 4GR0A 1UMSA 1ZS0A 1I73A 1OO9A 2OXUA 3F18A 1PWWA 2JSDA 1GO8P 1PWPA 2MZEA 2QPJA 1XUDA 4AXQA 5D1TA 2YUFA 1UTZA 4PKWA 1IAEA 2E3XA 1FBLA 1UMTA 3TVCA 1ZVXA 4Q1LA 1HFSA 1R1IA 2X3AA 1BIWA 2O3EA 3LIKA 1XUCA 2I47A 2ERQA 1USNA 3I7IA 2D1NA 4XM6A 5CUHA 3HB2P 3WV3A 3VI1A 1ND1A 2RJQA 1YCMA 4GF1A 3P1VA 3RTSA 1I1IP 3ZVSA 2XS4A 1XFXA 4I35A 2W13A 3OHOA 4I03A 2X3BA 1XFVA 5I43A 5H8XA 3U1RA 3KMEA 3P24A 1CQRA 3LQBA 1HFCA 3DWBA 4ILWD 2K9CA 1KUHA 3LJZA 4FVLA 4H2EA 1EB6A 1YP1A 5B5PA 4IJOA 4GWMA 456CA 2TCLA 1BQOA 4HX3A 2OXWA 5I0LA 3HY7A 1DTHA 3DPEA 4L6TA 1ZTQA 2Z2DA 4AYKA 2MLSA 2Y6CA 3V96B 4IUWA 1XFYA 1XFUA 4AIGA 1Y93A 1DMTA 3LJGA 1RM8A 3WV2A 1BUVM 1BUDA 3I7GA 1I76A 2OVXA 4GWNA 4H30A 2JIHA 4DV8A 2OZRA 3WV1A 1CGFA 3F15A 3LE9A 3B2ZA 3DTIA 3EWJA 2EROA 3EDIA 3GBOA 3KRYA 5BOYA 4XBHA 5I3MA 3LUNA 3G5CA 1MMRA 4GQLA 1CGLA 1JIZA 1ROSA 3EHYA 4AUOA 3USNA 1SRPA 1QIAA 3Q2GA 4CTHA 3DL1A 4H82A 5BOTA 1KAPP 1ZP5A 1KUKA 3HYGA 1RMZA 4H76A 5I12A 1XFZA 4XM7A 1PWUA 4GR3A 1G9KA 1D5JA 1YQYA 1AKLA 1G49A 1R54A 3Q2HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1R1H A;  1JK3 A;  3OHL A;  2JNP A;  4FXY P;  3LIL A;  3HBV P;  1CIZ A;  2XS3 A;  3LEA A;  1BQQ M;  3LGP A;  3KWV C;  1JAN A;  2CKI A;  3EHX A;  2O36 A;  4DF9 A;  3KEJ A;  5D3C A;  4DPE A;  1G05 A;  2SRT A;  1K7Q A;  2V4B A;  3SHI A;  1MMB A;  1QUA A;  3EDG A;  1O0Q A;  2OVZ A;  1A86 A;  5L7F A;  1SLN A;  2X3C A;  1SLM A;  1GE6 A;  5I2Z A;  1YOU A;  1CGE A;  4GUY A;  1SMP A;  1OM7 A;  3KHI A;  4R3V A;  3EDZ A;  1R55 A;  1BSW A;  3N2U A;  1A85 A;  3K7N A;  3ZUK A;  1IAB A;  1IAC A;  1BKC A;  1IAG A;  1ZXV A;  3DNG A;  4WF6 A;  2MLR A;  2FV5 A;  3DSL A;  4WK7 A;  1UTT A;  2OY2 A;  2DW0 A;  4J4M A;  1OM8 A;  1SU3 A;  2JT6 A;  3AIG A;  1HTD A;  2HU6 A;  1D8M A;  4DD8 A;  1C8T A;  1UEA A;  2OW1 A;  4G9L A;  1CXV A;  1EAK A;  2PJT A;  4ZR5 A;  4G0D A;  3B92 A;  1GE5 A;  4PKT A;  1PWV A;  4H3X A;  2W0D A;  3ZXH A;  2J83 A;  3G42 A;  5L79 A;  3F1A A;  2X7M A;  3TSK A;  2L0R A;  4HMA A;  4L63 A;  1D8F A;  1IAD A;  1GKC A;  1QJI A;  4XM8 A;  3LK8 A;  1OS9 A;  1C3I A;  5BPA A;  4H84 A;  2J0T A;  5B5O A;  2WO8 A;  2USN A;  3HDA P;  1FM1 A;  1G12 A;  2FV9 A;  3KEK A;  3KEC A;  1OMJ A;  1JAP A;  3AYU A;  3E8R A;  1CAQ A;  2YB9 A;  3HBU P;  4PKQ A;  1FLS A;  3EDH A;  3NX7 A;  4A3W A;  4ON1 A;  2A8H A;  4QKZ A;  1Y8J A;  2DW2 A;  1CK7 A;  2OY4 A;  3UVC A;  2WO9 A;  4EFS A;  2AYK A;  2DDY A;  1AYK A;  1BZS A;  2MZH A;  3LIR A;  5D2B A;  1Q3A A;  1AST A;  1Z3J A;  4WKI A;  3TT4 A;  1GXD A;  4WKE A;  1XFW A;  3LJT A;  1H71 P;  1OM6 A;  3F16 A;  2POJ A;  5D7W A;  1IAA A;  1BKC I;  3AYK A;  1B8Y A;  2ERP A;  4JP4 A;  3LUM A;  1SAT A;  3LQ0 A;  4JIJ A;  1EUB A;  5LAB A;  3N2V A;  2W14 A;  1MMQ A;  4IN9 A;  4JQG A;  3VTG A;  3L0V A;  3KMC A;  1C7K A;  1R1J A;  1JJ9 A;  2OXZ A;  1K7G A;  3BA0 A;  3HDB A;  2WOA A;  1ATL A;  1MMP A;  1WNI A;  3K7L A;  4JPA A;  1JIW P;  3O64 A;  2E2D A;  4L19 A;  1JAO A;  2OW9 A;  4PKS A;  2W15 A;  1G4K A;  1HV5 A;  2DDF A;  1AF0 A;  1KUF A;  2JT5 A;  5D1U A;  1JH1 A;  2OI0 A;  2K2G A;  1JKY A;  1GO7 P;  966C A;  1QIC A;  5CXA A;  4A7B A;  1HOV A;  3F17 A;  1KUG A;  3ELM A;  4PKV A;  1B3D A;  1JAQ A;  1OS2 A;  2DW1 A;  1GE7 A;  4GR8 A;  4WZV A;  5CZM A;  3LKA A;  1HY7 A;  3DPF A;  4FU4 A;  3MA2 A;  1BKC E;  3TS4 A;  1KUI A;  1K7I A;  5I4O A;  2KRJ A;  4XCT A;  1S4B P;  1QIB A;  3O2X A;  2Y6D A;  1XUR A;  4H49 A;  2YIG A;  1MNC A;  2CLT A;  1J7N A;  2N8R A;  1KBC A;  3L0T A;  1L6J A;  3B8Z A;  1QJJ A;  1Y0V A;  1GKD A;  4FXQ A;  5JMY A;  3LMC A;  830C A;  5D1S A;  3RTT A;  1ZXC A;  2OW2 A;  1BM6 A;  4PKU A;  2RJP A;  2MZI A;  4H1Q A;  4JA1 A;  1PWQ A;  2D1O A;  2OW0 A;  2AIG P;  1O0T A;  4PKR A;  1D7X A;  3CKI A;  2W12 A;  3F19 A;  3HY9 A;  4GR0 A;  1UMS A;  1ZS0 A;  1I73 A;  1OO9 A;  2OXU A;  3F18 A;  1PWW A;  2JSD A;  1GO8 P;  1PWP A;  2MZE A;  2QPJ A;  1XUD A;  4AXQ A;  5D1T A;  1UTZ A;  4PKW A;  1IAE A;  2E3X A;  1FBL A;  1UMT A;  3TVC A;  1ZVX A;  4Q1L A;  1HFS A;  1R1I A;  2X3A A;  1BIW A;  2O3E A;  3LIK A;  1XUC A;  2I47 A;  2ERQ A;  1USN A;  3I7I A;  2D1N A;  4XM6 A;  5CUH A;  3HB2 P;  3WV3 A;  3VI1 A;  1ND1 A;  2RJQ A;  1YCM A;  4GF1 A;  3P1V A;  3RTS A;  1I1I P;  3ZVS A;  2XS4 A;  1XFX A;  4I35 A;  2W13 A;  3OHO A;  4I03 A;  2X3B A;  1XFV A;  5I43 A;  5H8X A;  3U1R A;  3KME A;  3P24 A;  1CQR A;  3LQB A;  1HFC A;  3DWB A;  4ILW D;  2K9C A;  1KUH A;  3LJZ A;  4FVL A;  4H2E A;  1EB6 A;  1YP1 A;  5B5P A;  4IJO A;  4GWM A;  456C A;  2TCL A;  1BQO A;  4HX3 A;  2OXW A;  5I0L A;  3HY7 A;  1DTH A;  3DPE A;  4L6T A;  1ZTQ A;  2Z2D A;  4AYK A;  2MLS A;  2Y6C A;  3V96 B;  4IUW A;  1XFY A;  1XFU A;  4AIG A;  1Y93 A;  1DMT A;  3LJG A;  1RM8 A;  3WV2 A;  1BUV M;  1BUD A;  3I7G A;  1I76 A;  2OVX A;  4GWN A;  4H30 A;  2JIH A;  4DV8 A;  2OZR A;  3WV1 A;  1CGF A;  3F15 A;  3LE9 A;  3B2Z A;  3EWJ A;  2ERO A;  3EDI A;  3GBO A;  3KRY A;  5BOY A;  4XBH A;  5I3M A;  3LUN A;  3G5C A;  1MMR A;  4GQL A;  1CGL A;  1JIZ A;  1ROS A;  3EHY A;  4AUO A;  3USN A;  1SRP A;  1QIA A;  3Q2G A;  4CTH A;  3DL1 A;  4H82 A;  5BOT A;  1KAP P;  1ZP5 A;  1KUK A;  3HYG A;  1RMZ A;  4H76 A;  5I12 A;  1XFZ A;  4XM7 A;  1PWU A;  4GR3 A;  1G9K A;  1D5J A;  1YQY A;  1AKL A;  1G49 A;  1R54 A;  3Q2H A; 
#chains in the Genus database with same CATH topology
 1R1H A;  1JK3 A;  3OHL A;  2JNP A;  4FXY P;  3LIL A;  3HBV P;  1CIZ A;  2XS3 A;  3LEA A;  1BQQ M;  3LGP A;  3KWV C;  1JAN A;  2CKI A;  3EHX A;  2O36 A;  4DF9 A;  3KEJ A;  5D3C A;  4DPE A;  1G05 A;  2SRT A;  1K7Q A;  2V4B A;  3SHI A;  1MMB A;  1QUA A;  3EDG A;  1O0Q A;  2OVZ A;  1A86 A;  3DTK A;  5L7F A;  1SLN A;  2X3C A;  1SLM A;  1GE6 A;  5I2Z A;  1YOU A;  1CGE A;  4GUY A;  1SMP A;  1OM7 A;  3KHI A;  4R3V A;  3EDZ A;  1R55 A;  1BSW A;  3N2U A;  1A85 A;  3K7N A;  3ZUK A;  1IAB A;  1IAC A;  1BKC A;  1IAG A;  1ZXV A;  3DNG A;  4WF6 A;  2MLR A;  2FV5 A;  3DSL A;  4WK7 A;  1UTT A;  2OY2 A;  2DW0 A;  4J4M A;  1OM8 A;  1SU3 A;  2JT6 A;  3AIG A;  1HTD A;  2HU6 A;  1D8M A;  4DD8 A;  1C8T A;  1UEA A;  2OW1 A;  4G9L A;  1CXV A;  1EAK A;  2PJT A;  4ZR5 A;  4G0D A;  3B92 A;  1GE5 A;  4PKT A;  1PWV A;  4H3X A;  2W0D A;  3ZXH A;  2J83 A;  3G42 A;  5L79 A;  3F1A A;  1TVI A;  2X7M A;  3TSK A;  2L0R A;  4HMA A;  4L63 A;  1D8F A;  1IAD A;  1GKC A;  1QJI A;  4L7A A;  4XM8 A;  3LK8 A;  1OS9 A;  1C3I A;  5BPA A;  4H84 A;  2J0T A;  5B5O A;  2WO8 A;  2USN A;  3HDA P;  1FM1 A;  1G12 A;  2FV9 A;  3KEK A;  3KEC A;  1OMJ A;  1JAP A;  3AYU A;  3E8R A;  1XAX A;  1CAQ A;  2YB9 A;  3HBU P;  4PKQ A;  1FLS A;  3EDH A;  3NX7 A;  4A3W A;  4ON1 A;  2A8H A;  4QKZ A;  1Y8J A;  2DW2 A;  1CK7 A;  2OY4 A;  3UVC A;  2WO9 A;  4EFS A;  2AYK A;  2DDY A;  1AYK A;  1BZS A;  2MZH A;  3LIR A;  5D2B A;  1Q3A A;  1AST A;  1Z3J A;  4WKI A;  3TT4 A;  1GXD A;  4WKE A;  1XFW A;  3LJT A;  1H71 P;  1OM6 A;  3F16 A;  2POJ A;  5D7W A;  1IAA A;  1BKC I;  3AYK A;  1B8Y A;  2ERP A;  4JP4 A;  3LUM A;  1SAT A;  3LQ0 A;  4JIJ A;  1EUB A;  5LAB A;  3N2V A;  2W14 A;  1MMQ A;  4IN9 A;  4JQG A;  3VTG A;  3L0V A;  3KMC A;  1C7K A;  3DTE A;  1R1J A;  1JJ9 A;  2OXZ A;  1K7G A;  3BA0 A;  3HDB A;  2WOA A;  1ATL A;  1MMP A;  1WNI A;  3K7L A;  4JPA A;  1JIW P;  3O64 A;  2E2D A;  4L19 A;  1JAO A;  2OW9 A;  4PKS A;  2W15 A;  1G4K A;  1HV5 A;  2DDF A;  1AF0 A;  1KUF A;  2JT5 A;  5D1U A;  1JH1 A;  2OI0 A;  2K2G A;  1JKY A;  1GO7 P;  966C A;  1QIC A;  5CXA A;  4A7B A;  1HOV A;  3F17 A;  1KUG A;  3ELM A;  4PKV A;  1B3D A;  1JAQ A;  1OS2 A;  2DW1 A;  1GE7 A;  4GR8 A;  4WZV A;  5CZM A;  3LKA A;  1HY7 A;  3DPF A;  4FU4 A;  3MA2 A;  1BKC E;  3TS4 A;  1KUI A;  1K7I A;  5I4O A;  2KRJ A;  4XCT A;  1S4B P;  1QIB A;  3O2X A;  2Y6D A;  1XUR A;  4H49 A;  2YIG A;  1MNC A;  2CLT A;  1J7N A;  2N8R A;  1KBC A;  3L0T A;  1L6J A;  3B8Z A;  1QJJ A;  1Y0V A;  1GKD A;  4FXQ A;  5JMY A;  3LMC A;  830C A;  5D1S A;  3RTT A;  1ZXC A;  2OW2 A;  1BM6 A;  4PKU A;  2RJP A;  2MZI A;  4H1Q A;  4JA1 A;  1PWQ A;  2D1O A;  2OW0 A;  2AIG P;  1O0T A;  4PKR A;  1D7X A;  3CKI A;  2W12 A;  3F19 A;  3HY9 A;  4GR0 A;  1UMS A;  1ZS0 A;  1I73 A;  1OO9 A;  2OXU A;  3F18 A;  1PWW A;  2JSD A;  1GO8 P;  1PWP A;  2MZE A;  2QPJ A;  1XUD A;  4AXQ A;  5D1T A;  2YUF A;  1UTZ A;  4PKW A;  1IAE A;  2E3X A;  1FBL A;  1UMT A;  3TVC A;  1ZVX A;  4Q1L A;  1HFS A;  1R1I A;  2X3A A;  1BIW A;  2O3E A;  3LIK A;  1XUC A;  2I47 A;  2ERQ A;  1USN A;  3I7I A;  2D1N A;  4XM6 A;  5CUH A;  3HB2 P;  3WV3 A;  3VI1 A;  1ND1 A;  2RJQ A;  1YCM A;  4GF1 A;  3P1V A;  3RTS A;  1I1I P;  3ZVS A;  2XS4 A;  1XFX A;  4I35 A;  2W13 A;  3OHO A;  4I03 A;  2X3B A;  1XFV A;  5I43 A;  5H8X A;  3U1R A;  3KME A;  3P24 A;  1CQR A;  3LQB A;  1HFC A;  3DWB A;  4ILW D;  2K9C A;  1KUH A;  3LJZ A;  4FVL A;  4H2E A;  1EB6 A;  1YP1 A;  5B5P A;  4IJO A;  4GWM A;  456C A;  2TCL A;  1BQO A;  4HX3 A;  2OXW A;  5I0L A;  3HY7 A;  1DTH A;  3DPE A;  4L6T A;  1ZTQ A;  2Z2D A;  4AYK A;  2MLS A;  2Y6C A;  3V96 B;  4IUW A;  1XFY A;  1XFU A;  4AIG A;  1Y93 A;  1DMT A;  3LJG A;  1RM8 A;  3WV2 A;  1BUV M;  1BUD A;  3I7G A;  1I76 A;  2OVX A;  4GWN A;  1OZ9 A;  4H30 A;  2JIH A;  4DV8 A;  2OZR A;  3WV1 A;  1CGF A;  3F15 A;  3LE9 A;  3B2Z A;  3DTI A;  3EWJ A;  2ERO A;  3EDI A;  3GBO A;  3KRY A;  5BOY A;  4XBH A;  5I3M A;  3LUN A;  3G5C A;  1MMR A;  4GQL A;  1CGL A;  1XM5 A;  1JIZ A;  1ROS A;  3EHY A;  4AUO A;  3USN A;  1SRP A;  1QIA A;  3Q2G A;  4CTH A;  3DL1 A;  4H82 A;  5BOT A;  1KAP P;  1ZP5 A;  1KUK A;  3HYG A;  1RMZ A;  4H76 A;  5I12 A;  1XFZ A;  4XM7 A;  1PWU A;  4GR3 A;  1G9K A;  1D5J A;  1YQY A;  1AKL A;  1G49 A;  1R54 A;  3Q2H A; 
#chains in the Genus database with same CATH homology
 1R1H A;  1JK3 A;  3OHL A;  2JNP A;  4FXY P;  3LIL A;  3HBV P;  1CIZ A;  2XS3 A;  3LEA A;  1BQQ M;  3LGP A;  3KWV C;  1JAN A;  2CKI A;  3EHX A;  2O36 A;  4DF9 A;  3KEJ A;  5D3C A;  4DPE A;  1G05 A;  2SRT A;  1K7Q A;  2V4B A;  3SHI A;  1MMB A;  1QUA A;  3EDG A;  1O0Q A;  2OVZ A;  1A86 A;  3DTK A;  5L7F A;  1SLN A;  2X3C A;  1SLM A;  1GE6 A;  5I2Z A;  1YOU A;  1CGE A;  4GUY A;  1SMP A;  1OM7 A;  3KHI A;  4R3V A;  3EDZ A;  1R55 A;  1BSW A;  3N2U A;  1A85 A;  3K7N A;  3ZUK A;  1IAB A;  1IAC A;  1BKC A;  1IAG A;  1ZXV A;  3DNG A;  4WF6 A;  2MLR A;  2FV5 A;  3DSL A;  4WK7 A;  1UTT A;  2OY2 A;  2DW0 A;  4J4M A;  1OM8 A;  1SU3 A;  2JT6 A;  3AIG A;  1HTD A;  2HU6 A;  1D8M A;  4DD8 A;  1C8T A;  1UEA A;  2OW1 A;  4G9L A;  1CXV A;  1EAK A;  2PJT A;  4ZR5 A;  4G0D A;  3B92 A;  1GE5 A;  4PKT A;  1PWV A;  4H3X A;  2W0D A;  3ZXH A;  2J83 A;  3G42 A;  5L79 A;  3F1A A;  2X7M A;  3TSK A;  2L0R A;  4HMA A;  4L63 A;  1D8F A;  1IAD A;  1GKC A;  1QJI A;  4L7A A;  4XM8 A;  3LK8 A;  1OS9 A;  1C3I A;  5BPA A;  4H84 A;  2J0T A;  5B5O A;  2WO8 A;  2USN A;  3HDA P;  1FM1 A;  1G12 A;  2FV9 A;  3KEK A;  3KEC A;  1OMJ A;  1JAP A;  3AYU A;  3E8R A;  1CAQ A;  2YB9 A;  3HBU P;  4PKQ A;  1FLS A;  3EDH A;  3NX7 A;  4A3W A;  4ON1 A;  2A8H A;  4QKZ A;  1Y8J A;  2DW2 A;  1CK7 A;  2OY4 A;  3UVC A;  2WO9 A;  4EFS A;  2AYK A;  2DDY A;  1AYK A;  1BZS A;  2MZH A;  3LIR A;  5D2B A;  1Q3A A;  1AST A;  1Z3J A;  4WKI A;  3TT4 A;  1GXD A;  4WKE A;  1XFW A;  3LJT A;  1H71 P;  1OM6 A;  3F16 A;  2POJ A;  5D7W A;  1IAA A;  1BKC I;  3AYK A;  1B8Y A;  2ERP A;  4JP4 A;  3LUM A;  1SAT A;  3LQ0 A;  4JIJ A;  1EUB A;  5LAB A;  3N2V A;  2W14 A;  1MMQ A;  4IN9 A;  4JQG A;  3VTG A;  3L0V A;  3KMC A;  1C7K A;  3DTE A;  1R1J A;  1JJ9 A;  2OXZ A;  1K7G A;  3BA0 A;  3HDB A;  2WOA A;  1ATL A;  1MMP A;  1WNI A;  3K7L A;  4JPA A;  1JIW P;  3O64 A;  2E2D A;  4L19 A;  1JAO A;  2OW9 A;  4PKS A;  2W15 A;  1G4K A;  1HV5 A;  2DDF A;  1AF0 A;  1KUF A;  2JT5 A;  5D1U A;  1JH1 A;  2OI0 A;  2K2G A;  1JKY A;  1GO7 P;  966C A;  1QIC A;  5CXA A;  4A7B A;  1HOV A;  3F17 A;  1KUG A;  3ELM A;  4PKV A;  1B3D A;  1JAQ A;  1OS2 A;  2DW1 A;  1GE7 A;  4GR8 A;  4WZV A;  5CZM A;  3LKA A;  1HY7 A;  3DPF A;  4FU4 A;  3MA2 A;  1BKC E;  3TS4 A;  1KUI A;  1K7I A;  5I4O A;  2KRJ A;  4XCT A;  1S4B P;  1QIB A;  3O2X A;  2Y6D A;  1XUR A;  4H49 A;  2YIG A;  1MNC A;  2CLT A;  1J7N A;  2N8R A;  1KBC A;  3L0T A;  1L6J A;  3B8Z A;  1QJJ A;  1Y0V A;  1GKD A;  4FXQ A;  5JMY A;  3LMC A;  830C A;  5D1S A;  3RTT A;  1ZXC A;  2OW2 A;  1BM6 A;  4PKU A;  2RJP A;  2MZI A;  4H1Q A;  4JA1 A;  1PWQ A;  2D1O A;  2OW0 A;  2AIG P;  1O0T A;  4PKR A;  1D7X A;  3CKI A;  2W12 A;  3F19 A;  3HY9 A;  4GR0 A;  1UMS A;  1ZS0 A;  1I73 A;  1OO9 A;  2OXU A;  3F18 A;  1PWW A;  2JSD A;  1GO8 P;  1PWP A;  2MZE A;  2QPJ A;  1XUD A;  4AXQ A;  5D1T A;  2YUF A;  1UTZ A;  4PKW A;  1IAE A;  2E3X A;  1FBL A;  1UMT A;  3TVC A;  1ZVX A;  4Q1L A;  1HFS A;  1R1I A;  2X3A A;  1BIW A;  2O3E A;  3LIK A;  1XUC A;  2I47 A;  2ERQ A;  1USN A;  3I7I A;  2D1N A;  4XM6 A;  5CUH A;  3HB2 P;  3WV3 A;  3VI1 A;  1ND1 A;  2RJQ A;  1YCM A;  4GF1 A;  3P1V A;  3RTS A;  1I1I P;  3ZVS A;  2XS4 A;  1XFX A;  4I35 A;  2W13 A;  3OHO A;  4I03 A;  2X3B A;  1XFV A;  5I43 A;  5H8X A;  3U1R A;  3KME A;  3P24 A;  1CQR A;  3LQB A;  1HFC A;  3DWB A;  4ILW D;  2K9C A;  1KUH A;  3LJZ A;  4FVL A;  4H2E A;  1EB6 A;  1YP1 A;  5B5P A;  4IJO A;  4GWM A;  456C A;  2TCL A;  1BQO A;  4HX3 A;  2OXW A;  5I0L A;  3HY7 A;  1DTH A;  3DPE A;  4L6T A;  1ZTQ A;  2Z2D A;  4AYK A;  2MLS A;  2Y6C A;  3V96 B;  4IUW A;  1XFY A;  1XFU A;  4AIG A;  1Y93 A;  1DMT A;  3LJG A;  1RM8 A;  3WV2 A;  1BUV M;  1BUD A;  3I7G A;  1I76 A;  2OVX A;  4GWN A;  4H30 A;  2JIH A;  4DV8 A;  2OZR A;  3WV1 A;  1CGF A;  3F15 A;  3LE9 A;  3B2Z A;  3DTI A;  3EWJ A;  2ERO A;  3EDI A;  3GBO A;  3KRY A;  5BOY A;  4XBH A;  5I3M A;  3LUN A;  3G5C A;  1MMR A;  4GQL A;  1CGL A;  1JIZ A;  1ROS A;  3EHY A;  4AUO A;  3USN A;  1SRP A;  1QIA A;  3Q2G A;  4CTH A;  3DL1 A;  4H82 A;  5BOT A;  1KAP P;  1ZP5 A;  1KUK A;  3HYG A;  1RMZ A;  4H76 A;  5I12 A;  1XFZ A;  4XM7 A;  1PWU A;  4GR3 A;  1G9K A;  1D5J A;  1YQY A;  1AKL A;  1G49 A;  1R54 A;  3Q2H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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