1UTZA

Crystal structure of mmp-12 complexed to (2r)-3-({[4-[(pyridin-4-yl)phenyl]-thien-2-yl}carboxamido)(phenyl)propanoic acid
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
159
structure length
159
Chain Sequence
GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDFHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYGD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures of Novel Non-Peptidic, Non-Zinc Chelating Inhibitors Bound to Mmp-12
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords MACROPHAGE METALLOELASTASE
total genus 46
structure length 159
sequence length 159
chains with identical sequence B
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2003-12-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 1utzA00
2TCLA 4H82A 3KMEA 3RTSA 2DDYA 4XM8A 3USNA 3LUMA 1RM8A 1KAPP 4JQGA 1KUGA 1SLNA 4GUYA 1HOVA 2W13A 1XFWA 4QKZA 5D1TA 1AKLA 1QUAA 4CTHA 1CGEA 3LQ0A 4PKUA 1IABA 2J83A 1KUKA 2L0RA 3N2VA 1JIWP 1R1HA 1CAQA 5H8XA 5CXAA 2AIGP 3GBOA 5I4OA 2OY4A 3G5CA 3HY7A 2OI0A 1I76A 3HDBA 4L63A 1JKYA 4AUOA 2DW1A 1ASTA 1JK3A 3LK8A 4PKSA 1BQOA 3F16A 3LILA 1R1IA 2OY2A 2RJQA 3NX7A 1BKCE 4L6TA 1FM1A 4PKWA 1Z3JA 3F1AA 2MZHA 1JAPA 1PWUA 3CKIA 830CA 1SLMA 2W12A 2DW0A 4WKIA 3P24A 4JP4A 3P1VA 456CA 3WV2A 1OS9A 2K2GA 3DSLA 3LJTA 1D5JA 3O2XA 1JAQA 5B5PA 1HY7A 4AIGA 1KUHA 1ATLA 5BOTA 4XBHA 4H3XA 1MMBA 3VI1A 1Y0VA 1R55A 2OW0A 2X3AA 1PWWA 1CK7A 4H84A 4HMAA 1USNA 1XFYA 1UMTA 3DPEA 1QIAA 4Q1LA 1G9KA 1C7KA 3F15A 5I0LA 1G12A 4XCTA 4JA1A 3B92A 1Q3AA 2X3CA 1ZXCA 3TS4A 2X3BA 4WF6A 4WZVA 4HX3A 3KWVC 3EDZA 1UTTA 3HDAP 1HFCA 2W14A 2WO9A 3LEAA 5JMYA 4DPEA 1PWQA 1ZTQA 4H76A 4IUWA 1CQRA 3HBUP 2HU6A 1WNIA 1BZSA 3LQBA 2MZEA 3VTGA 2ERQA 4G0DA 1FBLA 1DMTA 1XFZA 2V4BA 2K9CA 1ZVXA 1BKCA 4H2EA 3EDHA 1CXVA 1G4KA 2O3EA 1DTHA 1IADA 1L6JA 1QIBA 1XFUA 1RMZA 1IAEA 1JANA 1K7GA 1ND1A 2JNPA 1XURA 4WK7A 1GE7A 4L19A 1H71P 2POJA 5D1SA 4GF1A 1GKCA 2WOAA 3TSKA 3K7NA 3WV3A 2JT5A 5BOYA 4AXQA 1HFSA 1GE5A 1OM7A 3TVCA 5I12A 1MNCA 966CA 3EWJA 3HYGA 2JT6A 3LIKA 4PKRA 2USNA 4G9LA 3TT4A 4EFSA 1O0TA 3DNGA 3DWBA 1S4BP 4DD8A 1EAKA 3OHOA 1YCMA 2A8HA 1BQQM 4A3WA 1BIWA 2QPJA 4GWNA 4AYKA 1ZXVA 2E3XA 4PKVA 4DF9A 3V96B 1AYKA 5D1UA 3ZUKA 1XFVA 3AYUA 3EDIA 4ILWD 3BA0A 1XUDA 4ON1A 5I3MA 1R1JA 2Z2DA 4I03A 1D7XA 2FV9A 1GXDA 3K7LA 1PWPA 3I7GA 4PKTA 3L0VA 4FXQA 1PWVA 4IJOA 2E2DA 4JIJA 1AF0A 1JIZA 1Y8JA 2Y6CA 4DV8A 3KRYA 3O64A 2CLTA 2DW2A 1GE6A 2YB9A 3LMCA 2XS3A 4GR3A 1MMQA 5I2ZA 1QJIA 2WO8A 3DL1A 1B3DA 1YP1A 1UTZA 3G42A 5D3CA 1A86A 4WKEA 1OMJA 3DPFA 1ROSA 3LUNA 1KUFA 1IAAA 5B5OA 4H1QA 2J0TA 2MZIA 3ZVSA 3KEJA 2W0DA 1I73A 1GKDA 2OXZA 2DDFA 3I7IA 2YIGA 2D1OA 4ZR5A 2O36A 1YQYA 3LE9A 4GR0A 5L79A 5CUHA 3ELMA 1KUIA 2KRJA 4GR8A 4FXYP 3KECA 1GO8P 1SRPA 1HV5A 3AYKA 2MLRA 1EB6A 2EROA 1CGFA 2JIHA 2FV5A 1R54A 3SHIA 4FVLA 4R3VA 2OW9A 2RJPA 4I35A 2OZRA 2XS4A 1J7NA 1CGLA 2I47A 1SU3A 1MMRA 2W15A 3LJGA 1O0QA 1BKCI 2OW1A 2SRTA 1HTDA 1OM6A 3LIRA 3L0TA 1IACA 1D8FA 2OVXA 1JAOA 1MMPA 1SMPA 1XFXA 1JJ9A 5BPAA 3EHXA 1BM6A 2ERPA 3UVCA 1G49A 2JSDA 4JPAA 4XM6A 1G05A 4GQLA 3F17A 3B8ZA 1I1IP 3HB2P 3KMCA 3E8RA 1IAGA 2OXUA 3HBVP 1CIZA 1Y93A 1B8YA 4XM7A 5D7WA 1C8TA 1C3IA 5L7FA 1UMSA 1K7QA 2OW2A 1BSWA 3KEKA 3N2UA 5D2BA 4H49A 4IN9A 1ZP5A 2Y6DA 1K7IA 3F18A 1A85A 1QICA 2MLSA 2AYKA 1OS2A 2OXWA 3Q2HA 2CKIA 1JH1A 3F19A 2D1NA 2OVZA 3OHLA 3Q2GA 4A7BA 1BUDA 3EDGA 3WV1A 4PKQA 1EUBA 3B2ZA 1OO9A 4J4MA 2X7MA 3KHIA 3MA2A 2N8RA 1GO7P 1KBCA 1SATA 3LKAA 1D8MA 3EHYA 5I43A 1YOUA 5LABA 3RTTA 3ZXHA 3LGPA 4H30A 3U1RA 2PJTA 1OM8A 4FU4A 3LJZA 1UEAA 4GWMA 5CZMA 1QJJA 1FLSA 3HY9A 1XUCA 3AIGA 1BUVM 1ZS0A
chains in the Genus database with same CATH superfamily
2TCLA 4H82A 3KMEA 3RTSA 2DDYA 4XM8A 3USNA 3LUMA 1RM8A 1KAPP 4JQGA 1KUGA 1SLNA 4GUYA 1HOVA 2W13A 1XFWA 4QKZA 5D1TA 1AKLA 1QUAA 4CTHA 1CGEA 3LQ0A 4PKUA 1IABA 2J83A 1KUKA 2L0RA 3N2VA 1JIWP 1R1HA 1CAQA 5H8XA 5CXAA 2AIGP 1XM5A 3GBOA 5I4OA 2OY4A 3G5CA 3HY7A 2OI0A 1OZ9A 1I76A 3HDBA 4L63A 1JKYA 4AUOA 2DW1A 1ASTA 1JK3A 3LK8A 4PKSA 1BQOA 3F16A 1R1IA 2OY2A 3LILA 2RJQA 3NX7A 1BKCE 4L6TA 1FM1A 4PKWA 1Z3JA 3F1AA 2MZHA 1JAPA 1PWUA 3CKIA 830CA 1SLMA 2W12A 2DW0A 4WKIA 3P24A 4JP4A 3P1VA 456CA 3WV2A 1OS9A 2K2GA 3DTEA 3DSLA 3LJTA 1D5JA 3O2XA 1JAQA 5B5PA 1HY7A 4AIGA 1KUHA 1ATLA 5BOTA 4XBHA 4H3XA 1MMBA 3VI1A 1Y0VA 1R55A 2OW0A 2X3AA 1PWWA 1CK7A 4H84A 4HMAA 1USNA 1XFYA 1UMTA 3DPEA 1QIAA 4Q1LA 1G9KA 1C7KA 3F15A 5I0LA 1G12A 4XCTA 4JA1A 3B92A 4L7AA 1Q3AA 2X3CA 1ZXCA 3TS4A 2X3BA 2YUFA 4WF6A 4WZVA 4HX3A 3KWVC 3EDZA 1UTTA 3HDAP 1HFCA 2W14A 2WO9A 3LEAA 5JMYA 4DPEA 1PWQA 1ZTQA 4H76A 4IUWA 1CQRA 3HBUP 2HU6A 1WNIA 1BZSA 3LQBA 2MZEA 3VTGA 2ERQA 4G0DA 1FBLA 1DMTA 1XFZA 2V4BA 2K9CA 1ZVXA 1BKCA 4H2EA 3EDHA 1CXVA 1G4KA 2O3EA 1DTHA 1IADA 1L6JA 1QIBA 1XFUA 1RMZA 1IAEA 1JANA 1K7GA 1ND1A 2JNPA 1XURA 4WK7A 1GE7A 4L19A 1H71P 2POJA 5D1SA 4GF1A 1GKCA 2WOAA 3TSKA 3K7NA 3WV3A 2JT5A 5BOYA 4AXQA 1HFSA 1GE5A 1OM7A 3TVCA 5I12A 1MNCA 966CA 3EWJA 3HYGA 2JT6A 3LIKA 4PKRA 2USNA 4G9LA 3TT4A 4EFSA 1O0TA 3DNGA 3DWBA 1S4BP 4DD8A 1EAKA 3OHOA 1YCMA 2A8HA 1BQQM 4A3WA 1BIWA 2QPJA 4GWNA 4AYKA 1ZXVA 2E3XA 4PKVA 4DF9A 3V96B 1AYKA 5D1UA 3ZUKA 1XFVA 3AYUA 3EDIA 4ILWD 3BA0A 1XUDA 1XAXA 4ON1A 5I3MA 1R1JA 2Z2DA 4I03A 1D7XA 2FV9A 1GXDA 3K7LA 1PWPA 3I7GA 4PKTA 3L0VA 4FXQA 1PWVA 4IJOA 2E2DA 4JIJA 1AF0A 1JIZA 1Y8JA 2Y6CA 4DV8A 3KRYA 3O64A 2CLTA 2DW2A 1GE6A 2YB9A 3LMCA 2XS3A 4GR3A 1MMQA 5I2ZA 1QJIA 2WO8A 3DL1A 1B3DA 1YP1A 1UTZA 3G42A 5D3CA 1A86A 4WKEA 3DTKA 1OMJA 3DPFA 1ROSA 3LUNA 1KUFA 1IAAA 5B5OA 4H1QA 1TVIA 2J0TA 2MZIA 3ZVSA 3KEJA 2W0DA 1I73A 1GKDA 2OXZA 2DDFA 3I7IA 2YIGA 2D1OA 4ZR5A 2O36A 1YQYA 3LE9A 4GR0A 5L79A 5CUHA 3ELMA 1KUIA 2KRJA 4GR8A 4FXYP 3KECA 1GO8P 1SRPA 1HV5A 3AYKA 2MLRA 1EB6A 2EROA 1CGFA 2JIHA 2FV5A 1R54A 3SHIA 4FVLA 4R3VA 2OW9A 2RJPA 4I35A 2OZRA 2XS4A 1J7NA 1CGLA 2I47A 1SU3A 1MMRA 2W15A 3LJGA 1O0QA 1BKCI 2OW1A 2SRTA 1HTDA 1OM6A 3LIRA 3L0TA 1IACA 1D8FA 2OVXA 1JAOA 1MMPA 1SMPA 1XFXA 1JJ9A 5BPAA 3EHXA 1BM6A 2ERPA 3DTIA 3UVCA 1G49A 2JSDA 4JPAA 4XM6A 1G05A 4GQLA 3F17A 3B8ZA 1I1IP 3HB2P 3KMCA 3E8RA 1IAGA 2OXUA 3HBVP 1CIZA 1Y93A 1B8YA 4XM7A 5D7WA 1C8TA 1C3IA 5L7FA 1UMSA 1K7QA 2OW2A 1BSWA 3KEKA 3N2UA 5D2BA 4H49A 4IN9A 1ZP5A 2Y6DA 1K7IA 3F18A 1A85A 1QICA 2MLSA 2AYKA 1OS2A 2OXWA 3Q2HA 2CKIA 1JH1A 3F19A 2D1NA 2OVZA 3OHLA 3Q2GA 4A7BA 1BUDA 3EDGA 3WV1A 4PKQA 1EUBA 3B2ZA 1OO9A 4J4MA 2X7MA 3KHIA 3MA2A 2N8RA 1GO7P 1KBCA 1SATA 3LKAA 1D8MA 3EHYA 5I43A 1YOUA 5LABA 3RTTA 3ZXHA 3LGPA 4H30A 3U1RA 2PJTA 1OM8A 4FU4A 3LJZA 1UEAA 4GWMA 5CZMA 1QJJA 1FLSA 3HY9A 1XUCA 3AIGA 1BUVM 1ZS0A
chains in the Genus database with same CATH topology
2TCLA 4H82A 3KMEA 3RTSA 2DDYA 4XM8A 3USNA 3LUMA 1RM8A 1KAPP 4JQGA 1KUGA 1SLNA 4GUYA 1HOVA 2W13A 1XFWA 4QKZA 5D1TA 1AKLA 1QUAA 4CTHA 1CGEA 3LQ0A 4PKUA 1IABA 2J83A 1KUKA 2L0RA 3N2VA 1JIWP 1R1HA 1CAQA 5H8XA 5CXAA 2AIGP 3GBOA 5I4OA 2OY4A 3G5CA 3HY7A 2OI0A 1I76A 3HDBA 4L63A 1JKYA 4AUOA 2DW1A 1ASTA 1JK3A 3LK8A 4PKSA 1BQOA 3F16A 3LILA 1R1IA 2OY2A 2RJQA 3NX7A 1BKCE 4L6TA 1FM1A 4PKWA 1Z3JA 3F1AA 2MZHA 1JAPA 1PWUA 3CKIA 830CA 1SLMA 2W12A 2DW0A 4WKIA 3P24A 4JP4A 3P1VA 456CA 3WV2A 1OS9A 2K2GA 3DTEA 3DSLA 3LJTA 1D5JA 3O2XA 1JAQA 5B5PA 1HY7A 4AIGA 1KUHA 1ATLA 5BOTA 4XBHA 4H3XA 1MMBA 3VI1A 1Y0VA 1R55A 2OW0A 2X3AA 1PWWA 1CK7A 4H84A 4HMAA 1USNA 1XFYA 1UMTA 3DPEA 1QIAA 4Q1LA 1G9KA 1C7KA 3F15A 5I0LA 1G12A 4XCTA 4JA1A 3B92A 4L7AA 1Q3AA 2X3CA 1ZXCA 3TS4A 2X3BA 2YUFA 4WF6A 4WZVA 4HX3A 3KWVC 3EDZA 1UTTA 3HDAP 1HFCA 2W14A 2WO9A 3LEAA 5JMYA 4DPEA 1PWQA 1ZTQA 4H76A 4IUWA 1CQRA 3HBUP 2HU6A 1WNIA 1BZSA 3LQBA 2MZEA 3VTGA 2ERQA 4G0DA 1FBLA 1DMTA 1XFZA 2V4BA 2K9CA 1ZVXA 1BKCA 4H2EA 3EDHA 1CXVA 1G4KA 2O3EA 1DTHA 1IADA 1L6JA 1QIBA 1XFUA 1RMZA 1IAEA 1JANA 1K7GA 1ND1A 2JNPA 1XURA 4WK7A 1GE7A 4L19A 1H71P 2POJA 5D1SA 4GF1A 1GKCA 2WOAA 3TSKA 3K7NA 3WV3A 2JT5A 5BOYA 4AXQA 1HFSA 1GE5A 1OM7A 3TVCA 5I12A 1MNCA 966CA 3EWJA 3HYGA 2JT6A 3LIKA 4PKRA 2USNA 4G9LA 3TT4A 4EFSA 1O0TA 3DNGA 3DWBA 1S4BP 4DD8A 1EAKA 3OHOA 1YCMA 2A8HA 1BQQM 4A3WA 1BIWA 2QPJA 4GWNA 4AYKA 1ZXVA 2E3XA 4PKVA 4DF9A 3V96B 1AYKA 5D1UA 3ZUKA 1XFVA 3AYUA 3EDIA 4ILWD 3BA0A 1XUDA 4ON1A 5I3MA 1R1JA 2Z2DA 4I03A 1D7XA 2FV9A 1GXDA 3K7LA 1PWPA 3I7GA 4PKTA 3L0VA 4FXQA 1PWVA 4IJOA 2E2DA 4JIJA 1AF0A 1JIZA 1Y8JA 2Y6CA 4DV8A 3KRYA 3O64A 2CLTA 2DW2A 1GE6A 2YB9A 3LMCA 2XS3A 4GR3A 1MMQA 5I2ZA 1QJIA 2WO8A 3DL1A 1B3DA 1YP1A 1UTZA 3G42A 5D3CA 1A86A 4WKEA 3DTKA 1OMJA 3DPFA 1ROSA 3LUNA 1KUFA 1IAAA 5B5OA 4H1QA 2J0TA 2MZIA 3ZVSA 3KEJA 2W0DA 1I73A 1GKDA 2OXZA 2DDFA 3I7IA 2YIGA 2D1OA 4ZR5A 2O36A 1YQYA 3LE9A 4GR0A 5L79A 5CUHA 3ELMA 1KUIA 2KRJA 4GR8A 4FXYP 3KECA 1GO8P 1SRPA 1HV5A 3AYKA 2MLRA 1EB6A 2EROA 1CGFA 2JIHA 2FV5A 1R54A 3SHIA 4FVLA 4R3VA 2OW9A 2RJPA 4I35A 2OZRA 2XS4A 1J7NA 1CGLA 2I47A 1SU3A 1MMRA 2W15A 3LJGA 1O0QA 1BKCI 2OW1A 2SRTA 1HTDA 1OM6A 3LIRA 3L0TA 1IACA 1D8FA 2OVXA 1JAOA 1MMPA 1SMPA 1XFXA 1JJ9A 5BPAA 3EHXA 1BM6A 2ERPA 3DTIA 3UVCA 1G49A 2JSDA 4JPAA 4XM6A 1G05A 4GQLA 3F17A 3B8ZA 1I1IP 3HB2P 3KMCA 3E8RA 1IAGA 2OXUA 3HBVP 1CIZA 1Y93A 1B8YA 4XM7A 5D7WA 1C8TA 1C3IA 5L7FA 1UMSA 1K7QA 2OW2A 1BSWA 3KEKA 3N2UA 5D2BA 4H49A 4IN9A 1ZP5A 2Y6DA 1K7IA 3F18A 1A85A 1QICA 2MLSA 2AYKA 1OS2A 2OXWA 3Q2HA 2CKIA 1JH1A 3F19A 2D1NA 2OVZA 3OHLA 3Q2GA 4A7BA 1BUDA 3EDGA 3WV1A 4PKQA 1EUBA 3B2ZA 1OO9A 4J4MA 2X7MA 3KHIA 3MA2A 2N8RA 1GO7P 1KBCA 1SATA 3LKAA 1D8MA 3EHYA 5I43A 1YOUA 5LABA 3RTTA 3ZXHA 3LGPA 4H30A 3U1RA 2PJTA 1OM8A 4FU4A 3LJZA 1UEAA 4GWMA 5CZMA 1QJJA 1FLSA 3HY9A 1XUCA 3AIGA 1BUVM 1ZS0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2TCL A;  4H82 A;  3KME A;  3RTS A;  2DDY A;  4XM8 A;  3USN A;  3LUM A;  1RM8 A;  1KAP P;  4JQG A;  1KUG A;  1SLN A;  4GUY A;  1HOV A;  2W13 A;  1XFW A;  4QKZ A;  5D1T A;  1AKL A;  1QUA A;  4CTH A;  1CGE A;  3LQ0 A;  4PKU A;  1IAB A;  2J83 A;  1KUK A;  2L0R A;  3N2V A;  1JIW P;  1R1H A;  1CAQ A;  5H8X A;  5CXA A;  2AIG P;  3GBO A;  5I4O A;  2OY4 A;  3G5C A;  3HY7 A;  2OI0 A;  1I76 A;  3HDB A;  4L63 A;  1JKY A;  4AUO A;  2DW1 A;  1AST A;  1JK3 A;  3LK8 A;  4PKS A;  1BQO A;  3F16 A;  3LIL A;  1R1I A;  2OY2 A;  2RJQ A;  3NX7 A;  1BKC E;  4L6T A;  1FM1 A;  4PKW A;  1Z3J A;  3F1A A;  2MZH A;  1JAP A;  1PWU A;  3CKI A;  830C A;  1SLM A;  2W12 A;  2DW0 A;  4WKI A;  3P24 A;  4JP4 A;  3P1V A;  456C A;  3WV2 A;  1OS9 A;  2K2G A;  3DSL A;  3LJT A;  1D5J A;  3O2X A;  1JAQ A;  5B5P A;  1HY7 A;  4AIG A;  1KUH A;  1ATL A;  5BOT A;  4XBH A;  4H3X A;  1MMB A;  3VI1 A;  1Y0V A;  1R55 A;  2OW0 A;  2X3A A;  1PWW A;  1CK7 A;  4H84 A;  4HMA A;  1USN A;  1XFY A;  1UMT A;  3DPE A;  1QIA A;  4Q1L A;  1G9K A;  1C7K A;  3F15 A;  5I0L A;  1G12 A;  4XCT A;  4JA1 A;  3B92 A;  1Q3A A;  2X3C A;  1ZXC A;  3TS4 A;  2X3B A;  4WF6 A;  4WZV A;  4HX3 A;  3KWV C;  3EDZ A;  1UTT A;  3HDA P;  1HFC A;  2W14 A;  2WO9 A;  3LEA A;  5JMY A;  4DPE A;  1PWQ A;  1ZTQ A;  4H76 A;  4IUW A;  1CQR A;  3HBU P;  2HU6 A;  1WNI A;  1BZS A;  3LQB A;  2MZE A;  3VTG A;  2ERQ A;  4G0D A;  1FBL A;  1DMT A;  1XFZ A;  2V4B A;  2K9C A;  1ZVX A;  1BKC A;  4H2E A;  3EDH A;  1CXV A;  1G4K A;  2O3E A;  1DTH A;  1IAD A;  1L6J A;  1QIB A;  1XFU A;  1RMZ A;  1IAE A;  1JAN A;  1K7G A;  1ND1 A;  2JNP A;  1XUR A;  4WK7 A;  1GE7 A;  4L19 A;  1H71 P;  2POJ A;  5D1S A;  4GF1 A;  1GKC A;  2WOA A;  3TSK A;  3K7N A;  3WV3 A;  2JT5 A;  5BOY A;  4AXQ A;  1HFS A;  1GE5 A;  1OM7 A;  3TVC A;  5I12 A;  1MNC A;  966C A;  3EWJ A;  3HYG A;  2JT6 A;  3LIK A;  4PKR A;  2USN A;  4G9L A;  3TT4 A;  4EFS A;  1O0T A;  3DNG A;  3DWB A;  1S4B P;  4DD8 A;  1EAK A;  3OHO A;  1YCM A;  2A8H A;  1BQQ M;  4A3W A;  1BIW A;  2QPJ A;  4GWN A;  4AYK A;  1ZXV A;  2E3X A;  4PKV A;  4DF9 A;  3V96 B;  1AYK A;  5D1U A;  3ZUK A;  1XFV A;  3AYU A;  3EDI A;  4ILW D;  3BA0 A;  1XUD A;  4ON1 A;  5I3M A;  1R1J A;  2Z2D A;  4I03 A;  1D7X A;  2FV9 A;  1GXD A;  3K7L A;  1PWP A;  3I7G A;  4PKT A;  3L0V A;  4FXQ A;  1PWV A;  4IJO A;  2E2D A;  4JIJ A;  1AF0 A;  1JIZ A;  1Y8J A;  2Y6C A;  4DV8 A;  3KRY A;  3O64 A;  2CLT A;  2DW2 A;  1GE6 A;  2YB9 A;  3LMC A;  2XS3 A;  4GR3 A;  1MMQ A;  5I2Z A;  1QJI A;  2WO8 A;  3DL1 A;  1B3D A;  1YP1 A;  1UTZ A;  3G42 A;  5D3C A;  1A86 A;  4WKE A;  1OMJ A;  3DPF A;  1ROS A;  3LUN A;  1KUF A;  1IAA A;  5B5O A;  4H1Q A;  2J0T A;  2MZI A;  3ZVS A;  3KEJ A;  2W0D A;  1I73 A;  1GKD A;  2OXZ A;  2DDF A;  3I7I A;  2YIG A;  2D1O A;  4ZR5 A;  2O36 A;  1YQY A;  3LE9 A;  4GR0 A;  5L79 A;  5CUH A;  3ELM A;  1KUI A;  2KRJ A;  4GR8 A;  4FXY P;  3KEC A;  1GO8 P;  1SRP A;  1HV5 A;  3AYK A;  2MLR A;  1EB6 A;  2ERO A;  1CGF A;  2JIH A;  2FV5 A;  1R54 A;  3SHI A;  4FVL A;  4R3V A;  2OW9 A;  2RJP A;  4I35 A;  2OZR A;  2XS4 A;  1J7N A;  1CGL A;  2I47 A;  1SU3 A;  1MMR A;  2W15 A;  3LJG A;  1O0Q A;  1BKC I;  2OW1 A;  2SRT A;  1HTD A;  1OM6 A;  3LIR A;  3L0T A;  1IAC A;  1D8F A;  2OVX A;  1JAO A;  1MMP A;  1SMP A;  1XFX A;  1JJ9 A;  5BPA A;  3EHX A;  1BM6 A;  2ERP A;  3UVC A;  1G49 A;  2JSD A;  4JPA A;  4XM6 A;  1G05 A;  4GQL A;  3F17 A;  3B8Z A;  1I1I P;  3HB2 P;  3KMC A;  3E8R A;  1IAG A;  2OXU A;  3HBV P;  1CIZ A;  1Y93 A;  1B8Y A;  4XM7 A;  5D7W A;  1C8T A;  1C3I A;  5L7F A;  1UMS A;  1K7Q A;  2OW2 A;  1BSW A;  3KEK A;  3N2U A;  5D2B A;  4H49 A;  4IN9 A;  1ZP5 A;  2Y6D A;  1K7I A;  3F18 A;  1A85 A;  1QIC A;  2MLS A;  2AYK A;  1OS2 A;  2OXW A;  3Q2H A;  2CKI A;  1JH1 A;  3F19 A;  2D1N A;  2OVZ A;  3OHL A;  3Q2G A;  4A7B A;  1BUD A;  3EDG A;  3WV1 A;  4PKQ A;  1EUB A;  3B2Z A;  1OO9 A;  4J4M A;  2X7M A;  3KHI A;  3MA2 A;  2N8R A;  1GO7 P;  1KBC A;  1SAT A;  3LKA A;  1D8M A;  3EHY A;  5I43 A;  1YOU A;  5LAB A;  3RTT A;  3ZXH A;  3LGP A;  4H30 A;  3U1R A;  2PJT A;  1OM8 A;  4FU4 A;  3LJZ A;  1UEA A;  4GWM A;  5CZM A;  1QJJ A;  1FLS A;  3HY9 A;  1XUC A;  3AIG A;  1BUV M;  1ZS0 A; 
#chains in the Genus database with same CATH topology
 2TCL A;  4H82 A;  3KME A;  3RTS A;  2DDY A;  4XM8 A;  3USN A;  3LUM A;  1RM8 A;  1KAP P;  4JQG A;  1KUG A;  1SLN A;  4GUY A;  1HOV A;  2W13 A;  1XFW A;  4QKZ A;  5D1T A;  1AKL A;  1QUA A;  4CTH A;  1CGE A;  3LQ0 A;  4PKU A;  1IAB A;  2J83 A;  1KUK A;  2L0R A;  3N2V A;  1JIW P;  1R1H A;  1CAQ A;  5H8X A;  5CXA A;  2AIG P;  1XM5 A;  3GBO A;  5I4O A;  2OY4 A;  3G5C A;  3HY7 A;  2OI0 A;  1OZ9 A;  1I76 A;  3HDB A;  4L63 A;  1JKY A;  4AUO A;  2DW1 A;  1AST A;  1JK3 A;  3LK8 A;  4PKS A;  1BQO A;  3F16 A;  1R1I A;  2OY2 A;  3LIL A;  2RJQ A;  3NX7 A;  1BKC E;  4L6T A;  1FM1 A;  4PKW A;  1Z3J A;  3F1A A;  2MZH A;  1JAP A;  1PWU A;  3CKI A;  830C A;  1SLM A;  2W12 A;  2DW0 A;  4WKI A;  3P24 A;  4JP4 A;  3P1V A;  456C A;  3WV2 A;  1OS9 A;  2K2G A;  3DTE A;  3DSL A;  3LJT A;  1D5J A;  3O2X A;  1JAQ A;  5B5P A;  1HY7 A;  4AIG A;  1KUH A;  1ATL A;  5BOT A;  4XBH A;  4H3X A;  1MMB A;  3VI1 A;  1Y0V A;  1R55 A;  2OW0 A;  2X3A A;  1PWW A;  1CK7 A;  4H84 A;  4HMA A;  1USN A;  1XFY A;  1UMT A;  3DPE A;  1QIA A;  4Q1L A;  1G9K A;  1C7K A;  3F15 A;  5I0L A;  1G12 A;  4XCT A;  4JA1 A;  3B92 A;  4L7A A;  1Q3A A;  2X3C A;  1ZXC A;  3TS4 A;  2X3B A;  2YUF A;  4WF6 A;  4WZV A;  4HX3 A;  3KWV C;  3EDZ A;  1UTT A;  3HDA P;  1HFC A;  2W14 A;  2WO9 A;  3LEA A;  5JMY A;  4DPE A;  1PWQ A;  1ZTQ A;  4H76 A;  4IUW A;  1CQR A;  3HBU P;  2HU6 A;  1WNI A;  1BZS A;  3LQB A;  2MZE A;  3VTG A;  2ERQ A;  4G0D A;  1FBL A;  1DMT A;  1XFZ A;  2V4B A;  2K9C A;  1ZVX A;  1BKC A;  4H2E A;  3EDH A;  1CXV A;  1G4K A;  2O3E A;  1DTH A;  1IAD A;  1L6J A;  1QIB A;  1XFU A;  1RMZ A;  1IAE A;  1JAN A;  1K7G A;  1ND1 A;  2JNP A;  1XUR A;  4WK7 A;  1GE7 A;  4L19 A;  1H71 P;  2POJ A;  5D1S A;  4GF1 A;  1GKC A;  2WOA A;  3TSK A;  3K7N A;  3WV3 A;  2JT5 A;  5BOY A;  4AXQ A;  1HFS A;  1GE5 A;  1OM7 A;  3TVC A;  5I12 A;  1MNC A;  966C A;  3EWJ A;  3HYG A;  2JT6 A;  3LIK A;  4PKR A;  2USN A;  4G9L A;  3TT4 A;  4EFS A;  1O0T A;  3DNG A;  3DWB A;  1S4B P;  4DD8 A;  1EAK A;  3OHO A;  1YCM A;  2A8H A;  1BQQ M;  4A3W A;  1BIW A;  2QPJ A;  4GWN A;  4AYK A;  1ZXV A;  2E3X A;  4PKV A;  4DF9 A;  3V96 B;  1AYK A;  5D1U A;  3ZUK A;  1XFV A;  3AYU A;  3EDI A;  4ILW D;  3BA0 A;  1XUD A;  1XAX A;  4ON1 A;  5I3M A;  1R1J A;  2Z2D A;  4I03 A;  1D7X A;  2FV9 A;  1GXD A;  3K7L A;  1PWP A;  3I7G A;  4PKT A;  3L0V A;  4FXQ A;  1PWV A;  4IJO A;  2E2D A;  4JIJ A;  1AF0 A;  1JIZ A;  1Y8J A;  2Y6C A;  4DV8 A;  3KRY A;  3O64 A;  2CLT A;  2DW2 A;  1GE6 A;  2YB9 A;  3LMC A;  2XS3 A;  4GR3 A;  1MMQ A;  5I2Z A;  1QJI A;  2WO8 A;  3DL1 A;  1B3D A;  1YP1 A;  1UTZ A;  3G42 A;  5D3C A;  1A86 A;  4WKE A;  3DTK A;  1OMJ A;  3DPF A;  1ROS A;  3LUN A;  1KUF A;  1IAA A;  5B5O A;  4H1Q A;  1TVI A;  2J0T A;  2MZI A;  3ZVS A;  3KEJ A;  2W0D A;  1I73 A;  1GKD A;  2OXZ A;  2DDF A;  3I7I A;  2YIG A;  2D1O A;  4ZR5 A;  2O36 A;  1YQY A;  3LE9 A;  4GR0 A;  5L79 A;  5CUH A;  3ELM A;  1KUI A;  2KRJ A;  4GR8 A;  4FXY P;  3KEC A;  1GO8 P;  1SRP A;  1HV5 A;  3AYK A;  2MLR A;  1EB6 A;  2ERO A;  1CGF A;  2JIH A;  2FV5 A;  1R54 A;  3SHI A;  4FVL A;  4R3V A;  2OW9 A;  2RJP A;  4I35 A;  2OZR A;  2XS4 A;  1J7N A;  1CGL A;  2I47 A;  1SU3 A;  1MMR A;  2W15 A;  3LJG A;  1O0Q A;  1BKC I;  2OW1 A;  2SRT A;  1HTD A;  1OM6 A;  3LIR A;  3L0T A;  1IAC A;  1D8F A;  2OVX A;  1JAO A;  1MMP A;  1SMP A;  1XFX A;  1JJ9 A;  5BPA A;  3EHX A;  1BM6 A;  2ERP A;  3DTI A;  3UVC A;  1G49 A;  2JSD A;  4JPA A;  4XM6 A;  1G05 A;  4GQL A;  3F17 A;  3B8Z A;  1I1I P;  3HB2 P;  3KMC A;  3E8R A;  1IAG A;  2OXU A;  3HBV P;  1CIZ A;  1Y93 A;  1B8Y A;  4XM7 A;  5D7W A;  1C8T A;  1C3I A;  5L7F A;  1UMS A;  1K7Q A;  2OW2 A;  1BSW A;  3KEK A;  3N2U A;  5D2B A;  4H49 A;  4IN9 A;  1ZP5 A;  2Y6D A;  1K7I A;  3F18 A;  1A85 A;  1QIC A;  2MLS A;  2AYK A;  1OS2 A;  2OXW A;  3Q2H A;  2CKI A;  1JH1 A;  3F19 A;  2D1N A;  2OVZ A;  3OHL A;  3Q2G A;  4A7B A;  1BUD A;  3EDG A;  3WV1 A;  4PKQ A;  1EUB A;  3B2Z A;  1OO9 A;  4J4M A;  2X7M A;  3KHI A;  3MA2 A;  2N8R A;  1GO7 P;  1KBC A;  1SAT A;  3LKA A;  1D8M A;  3EHY A;  5I43 A;  1YOU A;  5LAB A;  3RTT A;  3ZXH A;  3LGP A;  4H30 A;  3U1R A;  2PJT A;  1OM8 A;  4FU4 A;  3LJZ A;  1UEA A;  4GWM A;  5CZM A;  1QJJ A;  1FLS A;  3HY9 A;  1XUC A;  3AIG A;  1BUV M;  1ZS0 A; 
#chains in the Genus database with same CATH homology
 2TCL A;  4H82 A;  3KME A;  3RTS A;  2DDY A;  4XM8 A;  3USN A;  3LUM A;  1RM8 A;  1KAP P;  4JQG A;  1KUG A;  1SLN A;  4GUY A;  1HOV A;  2W13 A;  1XFW A;  4QKZ A;  5D1T A;  1AKL A;  1QUA A;  4CTH A;  1CGE A;  3LQ0 A;  4PKU A;  1IAB A;  2J83 A;  1KUK A;  2L0R A;  3N2V A;  1JIW P;  1R1H A;  1CAQ A;  5H8X A;  5CXA A;  2AIG P;  3GBO A;  5I4O A;  2OY4 A;  3G5C A;  3HY7 A;  2OI0 A;  1I76 A;  3HDB A;  4L63 A;  1JKY A;  4AUO A;  2DW1 A;  1AST A;  1JK3 A;  3LK8 A;  4PKS A;  1BQO A;  3F16 A;  3LIL A;  1R1I A;  2OY2 A;  2RJQ A;  3NX7 A;  1BKC E;  4L6T A;  1FM1 A;  4PKW A;  1Z3J A;  3F1A A;  2MZH A;  1JAP A;  1PWU A;  3CKI A;  830C A;  1SLM A;  2W12 A;  2DW0 A;  4WKI A;  3P24 A;  4JP4 A;  3P1V A;  456C A;  3WV2 A;  1OS9 A;  2K2G A;  3DTE A;  3DSL A;  3LJT A;  1D5J A;  3O2X A;  1JAQ A;  5B5P A;  1HY7 A;  4AIG A;  1KUH A;  1ATL A;  5BOT A;  4XBH A;  4H3X A;  1MMB A;  3VI1 A;  1Y0V A;  1R55 A;  2OW0 A;  2X3A A;  1PWW A;  1CK7 A;  4H84 A;  4HMA A;  1USN A;  1XFY A;  1UMT A;  3DPE A;  1QIA A;  4Q1L A;  1G9K A;  1C7K A;  3F15 A;  5I0L A;  1G12 A;  4XCT A;  4JA1 A;  3B92 A;  4L7A A;  1Q3A A;  2X3C A;  1ZXC A;  3TS4 A;  2X3B A;  2YUF A;  4WF6 A;  4WZV A;  4HX3 A;  3KWV C;  3EDZ A;  1UTT A;  3HDA P;  1HFC A;  2W14 A;  2WO9 A;  3LEA A;  5JMY A;  4DPE A;  1PWQ A;  1ZTQ A;  4H76 A;  4IUW A;  1CQR A;  3HBU P;  2HU6 A;  1WNI A;  1BZS A;  3LQB A;  2MZE A;  3VTG A;  2ERQ A;  4G0D A;  1FBL A;  1DMT A;  1XFZ A;  2V4B A;  2K9C A;  1ZVX A;  1BKC A;  4H2E A;  3EDH A;  1CXV A;  1G4K A;  2O3E A;  1DTH A;  1IAD A;  1L6J A;  1QIB A;  1XFU A;  1RMZ A;  1IAE A;  1JAN A;  1K7G A;  1ND1 A;  2JNP A;  1XUR A;  4WK7 A;  1GE7 A;  4L19 A;  1H71 P;  2POJ A;  5D1S A;  4GF1 A;  1GKC A;  2WOA A;  3TSK A;  3K7N A;  3WV3 A;  2JT5 A;  5BOY A;  4AXQ A;  1HFS A;  1GE5 A;  1OM7 A;  3TVC A;  5I12 A;  1MNC A;  966C A;  3EWJ A;  3HYG A;  2JT6 A;  3LIK A;  4PKR A;  2USN A;  4G9L A;  3TT4 A;  4EFS A;  1O0T A;  3DNG A;  3DWB A;  1S4B P;  4DD8 A;  1EAK A;  3OHO A;  1YCM A;  2A8H A;  1BQQ M;  4A3W A;  1BIW A;  2QPJ A;  4GWN A;  4AYK A;  1ZXV A;  2E3X A;  4PKV A;  4DF9 A;  3V96 B;  1AYK A;  5D1U A;  3ZUK A;  1XFV A;  3AYU A;  3EDI A;  4ILW D;  3BA0 A;  1XUD A;  4ON1 A;  5I3M A;  1R1J A;  2Z2D A;  4I03 A;  1D7X A;  2FV9 A;  1GXD A;  3K7L A;  1PWP A;  3I7G A;  4PKT A;  3L0V A;  4FXQ A;  1PWV A;  4IJO A;  2E2D A;  4JIJ A;  1AF0 A;  1JIZ A;  1Y8J A;  2Y6C A;  4DV8 A;  3KRY A;  3O64 A;  2CLT A;  2DW2 A;  1GE6 A;  2YB9 A;  3LMC A;  2XS3 A;  4GR3 A;  1MMQ A;  5I2Z A;  1QJI A;  2WO8 A;  3DL1 A;  1B3D A;  1YP1 A;  1UTZ A;  3G42 A;  5D3C A;  1A86 A;  4WKE A;  3DTK A;  1OMJ A;  3DPF A;  1ROS A;  3LUN A;  1KUF A;  1IAA A;  5B5O A;  4H1Q A;  2J0T A;  2MZI A;  3ZVS A;  3KEJ A;  2W0D A;  1I73 A;  1GKD A;  2OXZ A;  2DDF A;  3I7I A;  2YIG A;  2D1O A;  4ZR5 A;  2O36 A;  1YQY A;  3LE9 A;  4GR0 A;  5L79 A;  5CUH A;  3ELM A;  1KUI A;  2KRJ A;  4GR8 A;  4FXY P;  3KEC A;  1GO8 P;  1SRP A;  1HV5 A;  3AYK A;  2MLR A;  1EB6 A;  2ERO A;  1CGF A;  2JIH A;  2FV5 A;  1R54 A;  3SHI A;  4FVL A;  4R3V A;  2OW9 A;  2RJP A;  4I35 A;  2OZR A;  2XS4 A;  1J7N A;  1CGL A;  2I47 A;  1SU3 A;  1MMR A;  2W15 A;  3LJG A;  1O0Q A;  1BKC I;  2OW1 A;  2SRT A;  1HTD A;  1OM6 A;  3LIR A;  3L0T A;  1IAC A;  1D8F A;  2OVX A;  1JAO A;  1MMP A;  1SMP A;  1XFX A;  1JJ9 A;  5BPA A;  3EHX A;  1BM6 A;  2ERP A;  3DTI A;  3UVC A;  1G49 A;  2JSD A;  4JPA A;  4XM6 A;  1G05 A;  4GQL A;  3F17 A;  3B8Z A;  1I1I P;  3HB2 P;  3KMC A;  3E8R A;  1IAG A;  2OXU A;  3HBV P;  1CIZ A;  1Y93 A;  1B8Y A;  4XM7 A;  5D7W A;  1C8T A;  1C3I A;  5L7F A;  1UMS A;  1K7Q A;  2OW2 A;  1BSW A;  3KEK A;  3N2U A;  5D2B A;  4H49 A;  4IN9 A;  1ZP5 A;  2Y6D A;  1K7I A;  3F18 A;  1A85 A;  1QIC A;  2MLS A;  2AYK A;  1OS2 A;  2OXW A;  3Q2H A;  2CKI A;  1JH1 A;  3F19 A;  2D1N A;  2OVZ A;  3OHL A;  3Q2G A;  4A7B A;  1BUD A;  3EDG A;  3WV1 A;  4PKQ A;  1EUB A;  3B2Z A;  1OO9 A;  4J4M A;  2X7M A;  3KHI A;  3MA2 A;  2N8R A;  1GO7 P;  1KBC A;  1SAT A;  3LKA A;  1D8M A;  3EHY A;  5I43 A;  1YOU A;  5LAB A;  3RTT A;  3ZXH A;  3LGP A;  4H30 A;  3U1R A;  2PJT A;  1OM8 A;  4FU4 A;  3LJZ A;  1UEA A;  4GWM A;  5CZM A;  1QJJ A;  1FLS A;  3HY9 A;  1XUC A;  3AIG A;  1BUV M;  1ZS0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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