1YOUA

Crystal structure of the catalytic domain of mmp-13 complexed with a potent pyrimidinetrione inhibitor
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
168
structure length
168
Chain Sequence
YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPGDE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Potent pyrimidinetrione-based inhibitors of MMP-13 with enhanced selectivity over MMP-14.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Collagenase 3
total genus 49
structure length 168
sequence length 168
chains with identical sequence B
ec nomenclature ec 3.4.24.-:
pdb deposition date 2005-01-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 1youA00
1KUKA 2DDYA 1XFUA 3Q2HA 1QUAA 3RTSA 4JQGA 3P24A 5I43A 5I12A 4EFSA 4J4MA 3B92A 1GE7A 2ERQA 1JKYA 4XM6A 1R54A 2X7MA 3LKAA 2OY4A 3USNA 2D1NA 2USNA 3HBVP 1SLNA 4ZR5A 4GUYA 830CA 1OO9A 4XM8A 1ZP5A 1JH1A 2DW0A 1SRPA 966CA 1BKCA 1KBCA 1HFCA 2KRJA 3HY9A 4AYKA 5CUHA 1UMTA 3KMEA 1HOVA 1PWQA 1CAQA 1JANA 3I7IA 4H2EA 1AYKA 1ZXCA 1OS9A 4GWNA 3TSKA 1CXVA 1FBLA 1ASTA 4WK7A 4GWMA 1IAAA 2J0TA 1GKCA 4R3VA 1QIAA 4H1QA 1R1JA 3HDBA 1CIZA 2MZHA 4G9LA 1GO8P 5CZMA 2POJA 4DV8A 5I0LA 3HBUP 1G4KA 2MZIA 3LUMA 4PKVA 1FLSA 2FV5A 1MMRA 2CKIA 4PKQA 1RMZA 1AF0A 3HYGA 3ZXHA 3VTGA 4IUWA 2JSDA 2OW2A 4CTHA 2Y6DA 3DNGA 3F16A 1C8TA 1ZXVA 2OXZA 1Y0VA 3DPEA 3LMCA 4PKSA 1JAOA 1ND1A 5LABA 4JA1A 3U1RA 3KEKA 2EROA 4FU4A 1JIWP 2L0RA 3EWJA 5I4OA 1BQOA 1A85A 2PJTA 4PKUA 5D3CA 3AYUA 3EDHA 3LUNA 2V4BA 2W13A 2AYKA 3KMCA 5L7FA 2Y6CA 4A3WA 1WNIA 1EUBA 1QICA 3LE9A 1XUDA 3LK8A 3LQ0A 2WOAA 1PWPA 5B5OA 1RM8A 1GXDA 1DMTA 5CXAA 1BIWA 1XFYA 4XCTA 4GQLA 1DTHA 1SU3A 3AYKA 4IN9A 2W14A 1BUDA 2DW1A 2TCLA 3F19A 1OS2A 2JT6A 3GBOA 1IACA 1CGLA 3F18A 1KUFA 2DDFA 3G42A 2OXUA 1UTZA 5D2BA 4L19A 1OM7A 1MMQA 2MLRA 1C3IA 3HY7A 3O2XA 5JMYA 5I3MA 3LJZA 3F17A 2QPJA 1O0TA 1GO7P 3KHIA 1SATA 2X3CA 2OW0A 2WO9A 1GE6A 3LEAA 2N8RA 1I76A 1FM1A 3LJTA 2WO8A 1G49A 4ILWD 1Y93A 4Q1LA 4HMAA 4JP4A 3O64A 1D8FA 1R55A 1XFZA 1HFSA 3AIGA 1PWUA 3ZVSA 4XM7A 3DL1A 3EDZA 1K7IA 1YP1A 1BQQM 1D7XA 1JJ9A 1SMPA 5B5PA 4L63A 1K7QA 3MA2A 5L79A 3P1VA 2E3XA 1D8MA 3K7NA 2MLSA 4DPEA 1CGEA 2OXWA 3B2ZA 1L6JA 2FV9A 1B3DA 3OHLA 2YB9A 1CGFA 3WV3A 1KUIA 2W15A 4G0DA 2OI0A 1HTDA 2DW2A 3HB2P 4HX3A 4I03A 3UVCA 4ON1A 3DSLA 4WKEA 5D7WA 5BPAA 5H8XA 2YIGA 1IAGA 3N2UA 3KEJA 1G12A 3Q2GA 1BZSA 1QIBA 1HV5A 3ELMA 5BOYA 3F15A 1MNCA 2XS4A 1JAQA 1XFVA 4L6TA 4PKWA 4AIGA 2AIGP 1Y8JA 1BM6A 3LILA 1JK3A 1I73A 4H82A 3L0TA 3V96B 1BKCE 4GR8A 3LIRA 3N2VA 2OY2A 1UMSA 1XURA 1HY7A 1Q3AA 3CKIA 4GR3A 2W12A 5D1TA 5I2ZA 1ATLA 2RJPA 1PWWA 2A8HA 4H49A 1QJIA 1EB6A 4DF9A 1IABA 2D1OA 1KUGA 2MZEA 3LQBA 456CA 1R1HA 3E8RA 2X3AA 2J83A 4H76A 2OZRA 3OHOA 1J7NA 2Z2DA 2SRTA 4JPAA 1MMPA 3F1AA 1S4BP 2RJQA 2XS3A 1I1IP 3I7GA 2OW1A 3WV1A 3DPFA 3EHXA 1ZTQA 3L0VA 3K7LA 1KAPP 4A7BA 4PKRA 3G5CA 3LGPA 4GR0A 1XFXA 1KUHA 1BSWA 1ZS0A 1USNA 3KECA 4PKTA 3VI1A 4I35A 1EAKA 3LJGA 1A86A 3TT4A 4AXQA 4DD8A 2HU6A 1JAPA 1R1IA 3DWBA 1GKDA 1UEAA 4WKIA 1YOUA 2OVZA 2ERPA 1QJJA 1IAEA 1G9KA 4H84A 1ZVXA 3BA0A 2CLTA 1H71P 2X3BA 4FXQA 1C7KA 4IJOA 3KWVC 4GF1A 2I47A 3EDIA 4WF6A 1B8YA 1GE5A 1K7GA 3HDAP 1YCMA 1BUVM 3KRYA 4FVLA 4H3XA 1IADA 2K9CA 2O3EA 1UTTA 3B8ZA 4WZVA 3WV2A 4AUOA 1JIZA 2K2GA 1G05A 4H30A 1BKCI 1MMBA 2OW9A 2JT5A 3SHIA 2OVXA 1SLMA 3TVCA 2JIHA 3EDGA 1AKLA 5D1UA 3EHYA 3LIKA 1OM6A 1OM8A 1CK7A 1ROSA 1Z3JA 2W0DA 3NX7A 2O36A 1O0QA 4XBHA 5BOTA 1OMJA 4JIJA 3ZUKA 1D5JA 1XFWA 1YQYA 4FXYP 3TS4A 2E2DA 4QKZA 1PWVA 2JNPA 5D1SA 3RTTA 1XUCA 1CQRA
chains in the Genus database with same CATH superfamily
1KUKA 2DDYA 1XFUA 3Q2HA 1QUAA 3RTSA 4JQGA 3P24A 5I43A 5I12A 4EFSA 4J4MA 3B92A 1GE7A 2ERQA 1JKYA 4XM6A 1R54A 2X7MA 3LKAA 2OY4A 3USNA 2D1NA 2USNA 3HBVP 1SLNA 4ZR5A 4GUYA 830CA 1OO9A 4XM8A 1ZP5A 1JH1A 2DW0A 1SRPA 966CA 1BKCA 1KBCA 1HFCA 2KRJA 3HY9A 4AYKA 5CUHA 1UMTA 3KMEA 1HOVA 1PWQA 1CAQA 1JANA 3I7IA 4H2EA 1AYKA 1ZXCA 1OS9A 4GWNA 3TSKA 1CXVA 1FBLA 1ASTA 4WK7A 4GWMA 1IAAA 4L7AA 2J0TA 1GKCA 4R3VA 1QIAA 4H1QA 1R1JA 3HDBA 1CIZA 2MZHA 4G9LA 1GO8P 5CZMA 2POJA 4DV8A 5I0LA 3HBUP 1G4KA 2MZIA 3LUMA 4PKVA 1FLSA 2FV5A 1MMRA 2CKIA 4PKQA 1RMZA 1AF0A 3HYGA 3ZXHA 3VTGA 4IUWA 2JSDA 2OW2A 4CTHA 2Y6DA 3DNGA 3F16A 1C8TA 1ZXVA 2OXZA 3DTIA 1Y0VA 3DPEA 3DTKA 3LMCA 4PKSA 1JAOA 1ND1A 5LABA 4JA1A 3U1RA 3KEKA 2EROA 4FU4A 1JIWP 2L0RA 3EWJA 5I4OA 1BQOA 1A85A 2PJTA 4PKUA 5D3CA 3AYUA 3EDHA 3LUNA 2V4BA 2W13A 2AYKA 3KMCA 5L7FA 2Y6CA 4A3WA 1WNIA 1EUBA 1QICA 3LE9A 1XUDA 3LK8A 3LQ0A 2WOAA 1PWPA 5B5OA 1RM8A 1GXDA 1DMTA 5CXAA 1BIWA 1XFYA 4XCTA 4GQLA 1DTHA 1SU3A 3AYKA 4IN9A 2W14A 1BUDA 2DW1A 2TCLA 3F19A 1OS2A 2JT6A 3GBOA 1IACA 1CGLA 3F18A 1KUFA 2DDFA 3G42A 2OXUA 1UTZA 5D2BA 3DTEA 4L19A 1OM7A 1MMQA 2MLRA 1C3IA 3HY7A 3O2XA 5JMYA 5I3MA 3LJZA 3F17A 2QPJA 1O0TA 1GO7P 3KHIA 1SATA 2X3CA 2OW0A 2WO9A 1GE6A 3LEAA 2N8RA 1I76A 1FM1A 3LJTA 2WO8A 1G49A 4ILWD 1Y93A 4Q1LA 4HMAA 4JP4A 3O64A 1D8FA 1R55A 1XFZA 1HFSA 3AIGA 1PWUA 3ZVSA 4XM7A 3DL1A 3EDZA 1K7IA 1YP1A 1BQQM 1D7XA 1JJ9A 1SMPA 5B5PA 4L63A 1K7QA 3MA2A 5L79A 3P1VA 2E3XA 1D8MA 3K7NA 2MLSA 4DPEA 1CGEA 2OXWA 3B2ZA 1L6JA 2FV9A 1B3DA 3OHLA 2YB9A 1CGFA 3WV3A 1KUIA 2W15A 4G0DA 2OI0A 1HTDA 2DW2A 3HB2P 4HX3A 4I03A 3UVCA 4ON1A 3DSLA 4WKEA 5D7WA 5BPAA 5H8XA 2YIGA 1IAGA 3N2UA 3KEJA 1G12A 3Q2GA 1BZSA 1QIBA 1HV5A 3ELMA 5BOYA 3F15A 1MNCA 2XS4A 1JAQA 1XFVA 4L6TA 4PKWA 4AIGA 2AIGP 1Y8JA 1BM6A 3LILA 1JK3A 1I73A 4H82A 3L0TA 3V96B 1BKCE 4GR8A 3LIRA 3N2VA 2OY2A 1UMSA 1XURA 1HY7A 1Q3AA 3CKIA 4GR3A 2W12A 5D1TA 5I2ZA 1ATLA 2RJPA 1XM5A 1PWWA 2A8HA 4H49A 1QJIA 1EB6A 4DF9A 1IABA 2D1OA 1KUGA 2MZEA 3LQBA 456CA 1R1HA 3E8RA 2X3AA 2J83A 4H76A 2OZRA 3OHOA 1J7NA 2Z2DA 2SRTA 4JPAA 1MMPA 3F1AA 1S4BP 2RJQA 1TVIA 2XS3A 1I1IP 3I7GA 2OW1A 3WV1A 3DPFA 3EHXA 1ZTQA 3L0VA 3K7LA 1KAPP 4A7BA 4PKRA 3G5CA 3LGPA 4GR0A 1XFXA 1KUHA 1BSWA 1ZS0A 1USNA 3KECA 4PKTA 3VI1A 4I35A 1EAKA 3LJGA 1A86A 3TT4A 4AXQA 4DD8A 2HU6A 1JAPA 1R1IA 3DWBA 1GKDA 1UEAA 1XAXA 4WKIA 1YOUA 2OVZA 2ERPA 1QJJA 1IAEA 1G9KA 4H84A 1ZVXA 3BA0A 2CLTA 1H71P 2X3BA 4FXQA 1C7KA 4IJOA 3KWVC 4GF1A 2I47A 3EDIA 4WF6A 1B8YA 1GE5A 1K7GA 3HDAP 1YCMA 1BUVM 3KRYA 4FVLA 4H3XA 1IADA 2YUFA 2K9CA 2O3EA 1UTTA 3B8ZA 4WZVA 3WV2A 4AUOA 1JIZA 2K2GA 1G05A 4H30A 1BKCI 1MMBA 2OW9A 2JT5A 3SHIA 2OVXA 1OZ9A 1SLMA 3TVCA 2JIHA 3EDGA 1AKLA 5D1UA 3EHYA 3LIKA 1OM6A 1OM8A 1CK7A 1ROSA 1Z3JA 2W0DA 3NX7A 2O36A 1O0QA 4XBHA 5BOTA 1OMJA 4JIJA 3ZUKA 1D5JA 1XFWA 1YQYA 4FXYP 3TS4A 2E2DA 4QKZA 1PWVA 2JNPA 5D1SA 3RTTA 1XUCA 1CQRA
chains in the Genus database with same CATH topology
1KUKA 2DDYA 1XFUA 3Q2HA 1QUAA 3RTSA 4JQGA 3P24A 5I43A 5I12A 4EFSA 4J4MA 3B92A 1GE7A 2ERQA 1JKYA 4XM6A 1R54A 2X7MA 3LKAA 2OY4A 3USNA 2D1NA 2USNA 3HBVP 1SLNA 4ZR5A 4GUYA 830CA 1OO9A 4XM8A 1ZP5A 1JH1A 2DW0A 1SRPA 966CA 1BKCA 1KBCA 1HFCA 2KRJA 3HY9A 4AYKA 5CUHA 1UMTA 3KMEA 1HOVA 1PWQA 1CAQA 1JANA 3I7IA 4H2EA 1AYKA 1ZXCA 1OS9A 4GWNA 3TSKA 1CXVA 1FBLA 1ASTA 4WK7A 4GWMA 1IAAA 4L7AA 2J0TA 1GKCA 4R3VA 1QIAA 4H1QA 1R1JA 3HDBA 1CIZA 2MZHA 4G9LA 1GO8P 5CZMA 2POJA 4DV8A 5I0LA 3HBUP 1G4KA 2MZIA 3LUMA 4PKVA 1FLSA 2FV5A 1MMRA 2CKIA 4PKQA 1RMZA 1AF0A 3HYGA 3ZXHA 3VTGA 4IUWA 2JSDA 2OW2A 4CTHA 2Y6DA 3DNGA 3F16A 1C8TA 1ZXVA 2OXZA 3DTIA 1Y0VA 3DPEA 3DTKA 3LMCA 4PKSA 1JAOA 1ND1A 5LABA 4JA1A 3U1RA 3KEKA 2EROA 4FU4A 1JIWP 2L0RA 3EWJA 5I4OA 1BQOA 1A85A 2PJTA 4PKUA 5D3CA 3AYUA 3EDHA 3LUNA 2V4BA 2W13A 2AYKA 3KMCA 5L7FA 2Y6CA 4A3WA 1WNIA 1EUBA 1QICA 3LE9A 1XUDA 3LK8A 3LQ0A 2WOAA 1PWPA 5B5OA 1RM8A 1GXDA 1DMTA 5CXAA 1BIWA 1XFYA 4XCTA 4GQLA 1DTHA 1SU3A 3AYKA 4IN9A 2W14A 1BUDA 2DW1A 2TCLA 3F19A 1OS2A 2JT6A 3GBOA 1IACA 1CGLA 3F18A 1KUFA 2DDFA 3G42A 2OXUA 1UTZA 5D2BA 3DTEA 4L19A 1OM7A 1MMQA 2MLRA 1C3IA 3HY7A 3O2XA 5JMYA 5I3MA 3LJZA 3F17A 2QPJA 1O0TA 1GO7P 3KHIA 1SATA 2X3CA 2OW0A 2WO9A 1GE6A 3LEAA 2N8RA 1I76A 1FM1A 3LJTA 2WO8A 1G49A 4ILWD 1Y93A 4Q1LA 4HMAA 4JP4A 3O64A 1D8FA 1R55A 1XFZA 1HFSA 3AIGA 1PWUA 3ZVSA 4XM7A 3DL1A 3EDZA 1K7IA 1YP1A 1BQQM 1D7XA 1JJ9A 1SMPA 5B5PA 4L63A 1K7QA 3MA2A 5L79A 3P1VA 2E3XA 1D8MA 3K7NA 2MLSA 4DPEA 1CGEA 2OXWA 3B2ZA 1L6JA 2FV9A 1B3DA 3OHLA 2YB9A 1CGFA 3WV3A 1KUIA 2W15A 4G0DA 2OI0A 1HTDA 2DW2A 3HB2P 4HX3A 4I03A 3UVCA 4ON1A 3DSLA 4WKEA 5D7WA 5BPAA 5H8XA 2YIGA 1IAGA 3N2UA 3KEJA 1G12A 3Q2GA 1BZSA 1QIBA 1HV5A 3ELMA 5BOYA 3F15A 1MNCA 2XS4A 1JAQA 1XFVA 4L6TA 4PKWA 4AIGA 2AIGP 1Y8JA 1BM6A 3LILA 1JK3A 1I73A 4H82A 3L0TA 3V96B 1BKCE 4GR8A 3LIRA 3N2VA 2OY2A 1UMSA 1XURA 1HY7A 1Q3AA 3CKIA 4GR3A 2W12A 5D1TA 5I2ZA 1ATLA 2RJPA 1PWWA 2A8HA 4H49A 1QJIA 1EB6A 4DF9A 1IABA 2D1OA 1KUGA 2MZEA 3LQBA 456CA 1R1HA 3E8RA 2X3AA 2J83A 4H76A 2OZRA 3OHOA 1J7NA 2Z2DA 2SRTA 4JPAA 1MMPA 3F1AA 1S4BP 2RJQA 2XS3A 1I1IP 3I7GA 2OW1A 3WV1A 3DPFA 3EHXA 1ZTQA 3L0VA 3K7LA 1KAPP 4A7BA 4PKRA 3G5CA 3LGPA 4GR0A 1XFXA 1KUHA 1BSWA 1ZS0A 1USNA 3KECA 4PKTA 3VI1A 4I35A 1EAKA 3LJGA 1A86A 3TT4A 4AXQA 4DD8A 2HU6A 1JAPA 1R1IA 3DWBA 1GKDA 1UEAA 4WKIA 1YOUA 2OVZA 2ERPA 1QJJA 1IAEA 1G9KA 4H84A 1ZVXA 3BA0A 2CLTA 1H71P 2X3BA 4FXQA 1C7KA 4IJOA 3KWVC 4GF1A 2I47A 3EDIA 4WF6A 1B8YA 1GE5A 1K7GA 3HDAP 1YCMA 1BUVM 3KRYA 4FVLA 4H3XA 1IADA 2YUFA 2K9CA 2O3EA 1UTTA 3B8ZA 4WZVA 3WV2A 4AUOA 1JIZA 2K2GA 1G05A 4H30A 1BKCI 1MMBA 2OW9A 2JT5A 3SHIA 2OVXA 1SLMA 3TVCA 2JIHA 3EDGA 1AKLA 5D1UA 3EHYA 3LIKA 1OM6A 1OM8A 1CK7A 1ROSA 1Z3JA 2W0DA 3NX7A 2O36A 1O0QA 4XBHA 5BOTA 1OMJA 4JIJA 3ZUKA 1D5JA 1XFWA 1YQYA 4FXYP 3TS4A 2E2DA 4QKZA 1PWVA 2JNPA 5D1SA 3RTTA 1XUCA 1CQRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KUK A;  2DDY A;  1XFU A;  3Q2H A;  1QUA A;  3RTS A;  4JQG A;  3P24 A;  5I43 A;  5I12 A;  4EFS A;  4J4M A;  3B92 A;  1GE7 A;  2ERQ A;  1JKY A;  4XM6 A;  1R54 A;  2X7M A;  3LKA A;  2OY4 A;  3USN A;  2D1N A;  2USN A;  3HBV P;  1SLN A;  4ZR5 A;  4GUY A;  830C A;  1OO9 A;  4XM8 A;  1ZP5 A;  1JH1 A;  2DW0 A;  1SRP A;  966C A;  1BKC A;  1KBC A;  1HFC A;  2KRJ A;  3HY9 A;  4AYK A;  5CUH A;  1UMT A;  3KME A;  1HOV A;  1PWQ A;  1CAQ A;  1JAN A;  3I7I A;  4H2E A;  1AYK A;  1ZXC A;  1OS9 A;  4GWN A;  3TSK A;  1CXV A;  1FBL A;  1AST A;  4WK7 A;  4GWM A;  1IAA A;  2J0T A;  1GKC A;  4R3V A;  1QIA A;  4H1Q A;  1R1J A;  3HDB A;  1CIZ A;  2MZH A;  4G9L A;  1GO8 P;  5CZM A;  2POJ A;  4DV8 A;  5I0L A;  3HBU P;  1G4K A;  2MZI A;  3LUM A;  4PKV A;  1FLS A;  2FV5 A;  1MMR A;  2CKI A;  4PKQ A;  1RMZ A;  1AF0 A;  3HYG A;  3ZXH A;  3VTG A;  4IUW A;  2JSD A;  2OW2 A;  4CTH A;  2Y6D A;  3DNG A;  3F16 A;  1C8T A;  1ZXV A;  2OXZ A;  1Y0V A;  3DPE A;  3LMC A;  4PKS A;  1JAO A;  1ND1 A;  5LAB A;  4JA1 A;  3U1R A;  3KEK A;  2ERO A;  4FU4 A;  1JIW P;  2L0R A;  3EWJ A;  5I4O A;  1BQO A;  1A85 A;  2PJT A;  4PKU A;  5D3C A;  3AYU A;  3EDH A;  3LUN A;  2V4B A;  2W13 A;  2AYK A;  3KMC A;  5L7F A;  2Y6C A;  4A3W A;  1WNI A;  1EUB A;  1QIC A;  3LE9 A;  1XUD A;  3LK8 A;  3LQ0 A;  2WOA A;  1PWP A;  5B5O A;  1RM8 A;  1GXD A;  1DMT A;  5CXA A;  1BIW A;  1XFY A;  4XCT A;  4GQL A;  1DTH A;  1SU3 A;  3AYK A;  4IN9 A;  2W14 A;  1BUD A;  2DW1 A;  2TCL A;  3F19 A;  1OS2 A;  2JT6 A;  3GBO A;  1IAC A;  1CGL A;  3F18 A;  1KUF A;  2DDF A;  3G42 A;  2OXU A;  1UTZ A;  5D2B A;  4L19 A;  1OM7 A;  1MMQ A;  2MLR A;  1C3I A;  3HY7 A;  3O2X A;  5JMY A;  5I3M A;  3LJZ A;  3F17 A;  2QPJ A;  1O0T A;  1GO7 P;  3KHI A;  1SAT A;  2X3C A;  2OW0 A;  2WO9 A;  1GE6 A;  3LEA A;  2N8R A;  1I76 A;  1FM1 A;  3LJT A;  2WO8 A;  1G49 A;  4ILW D;  1Y93 A;  4Q1L A;  4HMA A;  4JP4 A;  3O64 A;  1D8F A;  1R55 A;  1XFZ A;  1HFS A;  3AIG A;  1PWU A;  3ZVS A;  4XM7 A;  3DL1 A;  3EDZ A;  1K7I A;  1YP1 A;  1BQQ M;  1D7X A;  1JJ9 A;  1SMP A;  5B5P A;  4L63 A;  1K7Q A;  3MA2 A;  5L79 A;  3P1V A;  2E3X A;  1D8M A;  3K7N A;  2MLS A;  4DPE A;  1CGE A;  2OXW A;  3B2Z A;  1L6J A;  2FV9 A;  1B3D A;  3OHL A;  2YB9 A;  1CGF A;  3WV3 A;  1KUI A;  2W15 A;  4G0D A;  2OI0 A;  1HTD A;  2DW2 A;  3HB2 P;  4HX3 A;  4I03 A;  3UVC A;  4ON1 A;  3DSL A;  4WKE A;  5D7W A;  5BPA A;  5H8X A;  2YIG A;  1IAG A;  3N2U A;  3KEJ A;  1G12 A;  3Q2G A;  1BZS A;  1QIB A;  1HV5 A;  3ELM A;  5BOY A;  3F15 A;  1MNC A;  2XS4 A;  1JAQ A;  1XFV A;  4L6T A;  4PKW A;  4AIG A;  2AIG P;  1Y8J A;  1BM6 A;  3LIL A;  1JK3 A;  1I73 A;  4H82 A;  3L0T A;  3V96 B;  1BKC E;  4GR8 A;  3LIR A;  3N2V A;  2OY2 A;  1UMS A;  1XUR A;  1HY7 A;  1Q3A A;  3CKI A;  4GR3 A;  2W12 A;  5D1T A;  5I2Z A;  1ATL A;  2RJP A;  1PWW A;  2A8H A;  4H49 A;  1QJI A;  1EB6 A;  4DF9 A;  1IAB A;  2D1O A;  1KUG A;  2MZE A;  3LQB A;  456C A;  1R1H A;  3E8R A;  2X3A A;  2J83 A;  4H76 A;  2OZR A;  3OHO A;  1J7N A;  2Z2D A;  2SRT A;  4JPA A;  1MMP A;  3F1A A;  1S4B P;  2RJQ A;  2XS3 A;  1I1I P;  3I7G A;  2OW1 A;  3WV1 A;  3DPF A;  3EHX A;  1ZTQ A;  3L0V A;  3K7L A;  1KAP P;  4A7B A;  4PKR A;  3G5C A;  3LGP A;  4GR0 A;  1XFX A;  1KUH A;  1BSW A;  1ZS0 A;  1USN A;  3KEC A;  4PKT A;  3VI1 A;  4I35 A;  1EAK A;  3LJG A;  1A86 A;  3TT4 A;  4AXQ A;  4DD8 A;  2HU6 A;  1JAP A;  1R1I A;  3DWB A;  1GKD A;  1UEA A;  4WKI A;  1YOU A;  2OVZ A;  2ERP A;  1QJJ A;  1IAE A;  1G9K A;  4H84 A;  1ZVX A;  3BA0 A;  2CLT A;  1H71 P;  2X3B A;  4FXQ A;  1C7K A;  4IJO A;  3KWV C;  4GF1 A;  2I47 A;  3EDI A;  4WF6 A;  1B8Y A;  1GE5 A;  1K7G A;  3HDA P;  1YCM A;  1BUV M;  3KRY A;  4FVL A;  4H3X A;  1IAD A;  2K9C A;  2O3E A;  1UTT A;  3B8Z A;  4WZV A;  3WV2 A;  4AUO A;  1JIZ A;  2K2G A;  1G05 A;  4H30 A;  1BKC I;  1MMB A;  2OW9 A;  2JT5 A;  3SHI A;  2OVX A;  1SLM A;  3TVC A;  2JIH A;  3EDG A;  1AKL A;  5D1U A;  3EHY A;  3LIK A;  1OM6 A;  1OM8 A;  1CK7 A;  1ROS A;  1Z3J A;  2W0D A;  3NX7 A;  2O36 A;  1O0Q A;  4XBH A;  5BOT A;  1OMJ A;  4JIJ A;  3ZUK A;  1D5J A;  1XFW A;  1YQY A;  4FXY P;  3TS4 A;  2E2D A;  4QKZ A;  1PWV A;  2JNP A;  5D1S A;  3RTT A;  1XUC A;  1CQR A; 
#chains in the Genus database with same CATH topology
 1KUK A;  2DDY A;  1XFU A;  3Q2H A;  1QUA A;  3RTS A;  4JQG A;  3P24 A;  5I43 A;  5I12 A;  4EFS A;  4J4M A;  3B92 A;  1GE7 A;  2ERQ A;  1JKY A;  4XM6 A;  1R54 A;  2X7M A;  3LKA A;  2OY4 A;  3USN A;  2D1N A;  2USN A;  3HBV P;  1SLN A;  4ZR5 A;  4GUY A;  830C A;  1OO9 A;  4XM8 A;  1ZP5 A;  1JH1 A;  2DW0 A;  1SRP A;  966C A;  1BKC A;  1KBC A;  1HFC A;  2KRJ A;  3HY9 A;  4AYK A;  5CUH A;  1UMT A;  3KME A;  1HOV A;  1PWQ A;  1CAQ A;  1JAN A;  3I7I A;  4H2E A;  1AYK A;  1ZXC A;  1OS9 A;  4GWN A;  3TSK A;  1CXV A;  1FBL A;  1AST A;  4WK7 A;  4GWM A;  1IAA A;  4L7A A;  2J0T A;  1GKC A;  4R3V A;  1QIA A;  4H1Q A;  1R1J A;  3HDB A;  1CIZ A;  2MZH A;  4G9L A;  1GO8 P;  5CZM A;  2POJ A;  4DV8 A;  5I0L A;  3HBU P;  1G4K A;  2MZI A;  3LUM A;  4PKV A;  1FLS A;  2FV5 A;  1MMR A;  2CKI A;  4PKQ A;  1RMZ A;  1AF0 A;  3HYG A;  3ZXH A;  3VTG A;  4IUW A;  2JSD A;  2OW2 A;  4CTH A;  2Y6D A;  3DNG A;  3F16 A;  1C8T A;  1ZXV A;  2OXZ A;  3DTI A;  1Y0V A;  3DPE A;  3DTK A;  3LMC A;  4PKS A;  1JAO A;  1ND1 A;  5LAB A;  4JA1 A;  3U1R A;  3KEK A;  2ERO A;  4FU4 A;  1JIW P;  2L0R A;  3EWJ A;  5I4O A;  1BQO A;  1A85 A;  2PJT A;  4PKU A;  5D3C A;  3AYU A;  3EDH A;  3LUN A;  2V4B A;  2W13 A;  2AYK A;  3KMC A;  5L7F A;  2Y6C A;  4A3W A;  1WNI A;  1EUB A;  1QIC A;  3LE9 A;  1XUD A;  3LK8 A;  3LQ0 A;  2WOA A;  1PWP A;  5B5O A;  1RM8 A;  1GXD A;  1DMT A;  5CXA A;  1BIW A;  1XFY A;  4XCT A;  4GQL A;  1DTH A;  1SU3 A;  3AYK A;  4IN9 A;  2W14 A;  1BUD A;  2DW1 A;  2TCL A;  3F19 A;  1OS2 A;  2JT6 A;  3GBO A;  1IAC A;  1CGL A;  3F18 A;  1KUF A;  2DDF A;  3G42 A;  2OXU A;  1UTZ A;  5D2B A;  3DTE A;  4L19 A;  1OM7 A;  1MMQ A;  2MLR A;  1C3I A;  3HY7 A;  3O2X A;  5JMY A;  5I3M A;  3LJZ A;  3F17 A;  2QPJ A;  1O0T A;  1GO7 P;  3KHI A;  1SAT A;  2X3C A;  2OW0 A;  2WO9 A;  1GE6 A;  3LEA A;  2N8R A;  1I76 A;  1FM1 A;  3LJT A;  2WO8 A;  1G49 A;  4ILW D;  1Y93 A;  4Q1L A;  4HMA A;  4JP4 A;  3O64 A;  1D8F A;  1R55 A;  1XFZ A;  1HFS A;  3AIG A;  1PWU A;  3ZVS A;  4XM7 A;  3DL1 A;  3EDZ A;  1K7I A;  1YP1 A;  1BQQ M;  1D7X A;  1JJ9 A;  1SMP A;  5B5P A;  4L63 A;  1K7Q A;  3MA2 A;  5L79 A;  3P1V A;  2E3X A;  1D8M A;  3K7N A;  2MLS A;  4DPE A;  1CGE A;  2OXW A;  3B2Z A;  1L6J A;  2FV9 A;  1B3D A;  3OHL A;  2YB9 A;  1CGF A;  3WV3 A;  1KUI A;  2W15 A;  4G0D A;  2OI0 A;  1HTD A;  2DW2 A;  3HB2 P;  4HX3 A;  4I03 A;  3UVC A;  4ON1 A;  3DSL A;  4WKE A;  5D7W A;  5BPA A;  5H8X A;  2YIG A;  1IAG A;  3N2U A;  3KEJ A;  1G12 A;  3Q2G A;  1BZS A;  1QIB A;  1HV5 A;  3ELM A;  5BOY A;  3F15 A;  1MNC A;  2XS4 A;  1JAQ A;  1XFV A;  4L6T A;  4PKW A;  4AIG A;  2AIG P;  1Y8J A;  1BM6 A;  3LIL A;  1JK3 A;  1I73 A;  4H82 A;  3L0T A;  3V96 B;  1BKC E;  4GR8 A;  3LIR A;  3N2V A;  2OY2 A;  1UMS A;  1XUR A;  1HY7 A;  1Q3A A;  3CKI A;  4GR3 A;  2W12 A;  5D1T A;  5I2Z A;  1ATL A;  2RJP A;  1XM5 A;  1PWW A;  2A8H A;  4H49 A;  1QJI A;  1EB6 A;  4DF9 A;  1IAB A;  2D1O A;  1KUG A;  2MZE A;  3LQB A;  456C A;  1R1H A;  3E8R A;  2X3A A;  2J83 A;  4H76 A;  2OZR A;  3OHO A;  1J7N A;  2Z2D A;  2SRT A;  4JPA A;  1MMP A;  3F1A A;  1S4B P;  2RJQ A;  1TVI A;  2XS3 A;  1I1I P;  3I7G A;  2OW1 A;  3WV1 A;  3DPF A;  3EHX A;  1ZTQ A;  3L0V A;  3K7L A;  1KAP P;  4A7B A;  4PKR A;  3G5C A;  3LGP A;  4GR0 A;  1XFX A;  1KUH A;  1BSW A;  1ZS0 A;  1USN A;  3KEC A;  4PKT A;  3VI1 A;  4I35 A;  1EAK A;  3LJG A;  1A86 A;  3TT4 A;  4AXQ A;  4DD8 A;  2HU6 A;  1JAP A;  1R1I A;  3DWB A;  1GKD A;  1UEA A;  1XAX A;  4WKI A;  1YOU A;  2OVZ A;  2ERP A;  1QJJ A;  1IAE A;  1G9K A;  4H84 A;  1ZVX A;  3BA0 A;  2CLT A;  1H71 P;  2X3B A;  4FXQ A;  1C7K A;  4IJO A;  3KWV C;  4GF1 A;  2I47 A;  3EDI A;  4WF6 A;  1B8Y A;  1GE5 A;  1K7G A;  3HDA P;  1YCM A;  1BUV M;  3KRY A;  4FVL A;  4H3X A;  1IAD A;  2YUF A;  2K9C A;  2O3E A;  1UTT A;  3B8Z A;  4WZV A;  3WV2 A;  4AUO A;  1JIZ A;  2K2G A;  1G05 A;  4H30 A;  1BKC I;  1MMB A;  2OW9 A;  2JT5 A;  3SHI A;  2OVX A;  1OZ9 A;  1SLM A;  3TVC A;  2JIH A;  3EDG A;  1AKL A;  5D1U A;  3EHY A;  3LIK A;  1OM6 A;  1OM8 A;  1CK7 A;  1ROS A;  1Z3J A;  2W0D A;  3NX7 A;  2O36 A;  1O0Q A;  4XBH A;  5BOT A;  1OMJ A;  4JIJ A;  3ZUK A;  1D5J A;  1XFW A;  1YQY A;  4FXY P;  3TS4 A;  2E2D A;  4QKZ A;  1PWV A;  2JNP A;  5D1S A;  3RTT A;  1XUC A;  1CQR A; 
#chains in the Genus database with same CATH homology
 1KUK A;  2DDY A;  1XFU A;  3Q2H A;  1QUA A;  3RTS A;  4JQG A;  3P24 A;  5I43 A;  5I12 A;  4EFS A;  4J4M A;  3B92 A;  1GE7 A;  2ERQ A;  1JKY A;  4XM6 A;  1R54 A;  2X7M A;  3LKA A;  2OY4 A;  3USN A;  2D1N A;  2USN A;  3HBV P;  1SLN A;  4ZR5 A;  4GUY A;  830C A;  1OO9 A;  4XM8 A;  1ZP5 A;  1JH1 A;  2DW0 A;  1SRP A;  966C A;  1BKC A;  1KBC A;  1HFC A;  2KRJ A;  3HY9 A;  4AYK A;  5CUH A;  1UMT A;  3KME A;  1HOV A;  1PWQ A;  1CAQ A;  1JAN A;  3I7I A;  4H2E A;  1AYK A;  1ZXC A;  1OS9 A;  4GWN A;  3TSK A;  1CXV A;  1FBL A;  1AST A;  4WK7 A;  4GWM A;  1IAA A;  4L7A A;  2J0T A;  1GKC A;  4R3V A;  1QIA A;  4H1Q A;  1R1J A;  3HDB A;  1CIZ A;  2MZH A;  4G9L A;  1GO8 P;  5CZM A;  2POJ A;  4DV8 A;  5I0L A;  3HBU P;  1G4K A;  2MZI A;  3LUM A;  4PKV A;  1FLS A;  2FV5 A;  1MMR A;  2CKI A;  4PKQ A;  1RMZ A;  1AF0 A;  3HYG A;  3ZXH A;  3VTG A;  4IUW A;  2JSD A;  2OW2 A;  4CTH A;  2Y6D A;  3DNG A;  3F16 A;  1C8T A;  1ZXV A;  2OXZ A;  3DTI A;  1Y0V A;  3DPE A;  3DTK A;  3LMC A;  4PKS A;  1JAO A;  1ND1 A;  5LAB A;  4JA1 A;  3U1R A;  3KEK A;  2ERO A;  4FU4 A;  1JIW P;  2L0R A;  3EWJ A;  5I4O A;  1BQO A;  1A85 A;  2PJT A;  4PKU A;  5D3C A;  3AYU A;  3EDH A;  3LUN A;  2V4B A;  2W13 A;  2AYK A;  3KMC A;  5L7F A;  2Y6C A;  4A3W A;  1WNI A;  1EUB A;  1QIC A;  3LE9 A;  1XUD A;  3LK8 A;  3LQ0 A;  2WOA A;  1PWP A;  5B5O A;  1RM8 A;  1GXD A;  1DMT A;  5CXA A;  1BIW A;  1XFY A;  4XCT A;  4GQL A;  1DTH A;  1SU3 A;  3AYK A;  4IN9 A;  2W14 A;  1BUD A;  2DW1 A;  2TCL A;  3F19 A;  1OS2 A;  2JT6 A;  3GBO A;  1IAC A;  1CGL A;  3F18 A;  1KUF A;  2DDF A;  3G42 A;  2OXU A;  1UTZ A;  5D2B A;  3DTE A;  4L19 A;  1OM7 A;  1MMQ A;  2MLR A;  1C3I A;  3HY7 A;  3O2X A;  5JMY A;  5I3M A;  3LJZ A;  3F17 A;  2QPJ A;  1O0T A;  1GO7 P;  3KHI A;  1SAT A;  2X3C A;  2OW0 A;  2WO9 A;  1GE6 A;  3LEA A;  2N8R A;  1I76 A;  1FM1 A;  3LJT A;  2WO8 A;  1G49 A;  4ILW D;  1Y93 A;  4Q1L A;  4HMA A;  4JP4 A;  3O64 A;  1D8F A;  1R55 A;  1XFZ A;  1HFS A;  3AIG A;  1PWU A;  3ZVS A;  4XM7 A;  3DL1 A;  3EDZ A;  1K7I A;  1YP1 A;  1BQQ M;  1D7X A;  1JJ9 A;  1SMP A;  5B5P A;  4L63 A;  1K7Q A;  3MA2 A;  5L79 A;  3P1V A;  2E3X A;  1D8M A;  3K7N A;  2MLS A;  4DPE A;  1CGE A;  2OXW A;  3B2Z A;  1L6J A;  2FV9 A;  1B3D A;  3OHL A;  2YB9 A;  1CGF A;  3WV3 A;  1KUI A;  2W15 A;  4G0D A;  2OI0 A;  1HTD A;  2DW2 A;  3HB2 P;  4HX3 A;  4I03 A;  3UVC A;  4ON1 A;  3DSL A;  4WKE A;  5D7W A;  5BPA A;  5H8X A;  2YIG A;  1IAG A;  3N2U A;  3KEJ A;  1G12 A;  3Q2G A;  1BZS A;  1QIB A;  1HV5 A;  3ELM A;  5BOY A;  3F15 A;  1MNC A;  2XS4 A;  1JAQ A;  1XFV A;  4L6T A;  4PKW A;  4AIG A;  2AIG P;  1Y8J A;  1BM6 A;  3LIL A;  1JK3 A;  1I73 A;  4H82 A;  3L0T A;  3V96 B;  1BKC E;  4GR8 A;  3LIR A;  3N2V A;  2OY2 A;  1UMS A;  1XUR A;  1HY7 A;  1Q3A A;  3CKI A;  4GR3 A;  2W12 A;  5D1T A;  5I2Z A;  1ATL A;  2RJP A;  1PWW A;  2A8H A;  4H49 A;  1QJI A;  1EB6 A;  4DF9 A;  1IAB A;  2D1O A;  1KUG A;  2MZE A;  3LQB A;  456C A;  1R1H A;  3E8R A;  2X3A A;  2J83 A;  4H76 A;  2OZR A;  3OHO A;  1J7N A;  2Z2D A;  2SRT A;  4JPA A;  1MMP A;  3F1A A;  1S4B P;  2RJQ A;  2XS3 A;  1I1I P;  3I7G A;  2OW1 A;  3WV1 A;  3DPF A;  3EHX A;  1ZTQ A;  3L0V A;  3K7L A;  1KAP P;  4A7B A;  4PKR A;  3G5C A;  3LGP A;  4GR0 A;  1XFX A;  1KUH A;  1BSW A;  1ZS0 A;  1USN A;  3KEC A;  4PKT A;  3VI1 A;  4I35 A;  1EAK A;  3LJG A;  1A86 A;  3TT4 A;  4AXQ A;  4DD8 A;  2HU6 A;  1JAP A;  1R1I A;  3DWB A;  1GKD A;  1UEA A;  4WKI A;  1YOU A;  2OVZ A;  2ERP A;  1QJJ A;  1IAE A;  1G9K A;  4H84 A;  1ZVX A;  3BA0 A;  2CLT A;  1H71 P;  2X3B A;  4FXQ A;  1C7K A;  4IJO A;  3KWV C;  4GF1 A;  2I47 A;  3EDI A;  4WF6 A;  1B8Y A;  1GE5 A;  1K7G A;  3HDA P;  1YCM A;  1BUV M;  3KRY A;  4FVL A;  4H3X A;  1IAD A;  2YUF A;  2K9C A;  2O3E A;  1UTT A;  3B8Z A;  4WZV A;  3WV2 A;  4AUO A;  1JIZ A;  2K2G A;  1G05 A;  4H30 A;  1BKC I;  1MMB A;  2OW9 A;  2JT5 A;  3SHI A;  2OVX A;  1SLM A;  3TVC A;  2JIH A;  3EDG A;  1AKL A;  5D1U A;  3EHY A;  3LIK A;  1OM6 A;  1OM8 A;  1CK7 A;  1ROS A;  1Z3J A;  2W0D A;  3NX7 A;  2O36 A;  1O0Q A;  4XBH A;  5BOT A;  1OMJ A;  4JIJ A;  3ZUK A;  1D5J A;  1XFW A;  1YQY A;  4FXY P;  3TS4 A;  2E2D A;  4QKZ A;  1PWV A;  2JNP A;  5D1S A;  3RTT A;  1XUC A;  1CQR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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