1ZXCA

Crystal structure of catalytic domain of tnf-alpha converting enzyme (tace) with inhibitor
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
259
structure length
259
Chain Sequence
DPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Acetylenic TACE inhibitors. Part 2: SAR of six-membered cyclic sulfonamide hydroxamates.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords ADAM 17
total genus 87
structure length 259
sequence length 259
chains with identical sequence B
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2005-06-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 1zxcA00
1GKCA 1I73A 3O2XA 5L7FA 1BZSA 3LQBA 3TVCA 2DW0A 5CXAA 1IAAA 1ND1A 2E3XA 1UMSA 1UMTA 4JP4A 1J7NA 4Q1LA 1FBLA 3EDIA 3DL1A 4DV8A 3BA0A 2OW0A 3EDGA 4I03A 2OVZA 2X3CA 3EHXA 1Z3JA 1GO8P 4WKIA 5B5PA 1R55A 4R3VA 1IAGA 1BKCE 2Y6CA 1DTHA 3F18A 4IUWA 2OW2A 2ERQA 5D2BA 4EFSA 5I12A 1BUDA 4FVLA 5BPAA 2JT6A 2J83A 3GBOA 4GUYA 3LEAA 2JNPA 3DPEA 3DSLA 1ZTQA 1OO9A 1XFZA 3K7NA 4WF6A 4FXYP 3LILA 3LMCA 456CA 1MMBA 1K7GA 2Y6DA 3U1RA 3LGPA 2D1NA 4JIJA 1XFWA 1PWWA 3KRYA 4XBHA 1UTZA 3WV2A 1ZVXA 3P24A 3LQ0A 3SHIA 5I3MA 1R54A 3HYGA 3EDZA 1CK7A 4FU4A 1RMZA 2Z2DA 1YOUA 1JANA 1WNIA 1Y93A 1Y8JA 2DW1A 3ELMA 1IAEA 3P1VA 1YCMA 3HY7A 3HBVP 4QKZA 1JIWP 2W15A 1I1IP 4HMAA 1BSWA 1K7IA 1KUKA 1GKDA 4PKTA 3E8RA 3KMEA 2K2GA 1YQYA 3EDHA 2FV5A 3N2VA 1XFYA 3KEKA 1UTTA 1EAKA 3UVCA 1XUDA 4WZVA 1L6JA 1XFXA 2AYKA 2X7MA 3B2ZA 3DWBA 1EUBA 1GE7A 1H71P 4CTHA 1KUHA 2AIGP 2WO8A 2MZIA 4JPAA 5D3CA 5I4OA 2JIHA 2D1OA 1XFUA 1YP1A 2OI0A 3HDBA 2OXWA 2POJA 4PKQA 3CKIA 3NX7A 1HY7A 5I2ZA 1CAQA 4HX3A 1PWVA 4G0DA 4WK7A 2E2DA 4I35A 1BM6A 3MA2A 3VI1A 4H76A 1R1JA 1ZXCA 2HU6A 3HY9A 2X3BA 4H49A 3V96B 4PKRA 2MZHA 1EB6A 1A85A 2OW1A 1B8YA 3F17A 4DD8A 1S4BP 830CA 1SRPA 1OM8A 4GQLA 1IABA 2ERPA 4GR3A 1OS9A 4H82A 3LJTA 3OHLA 3LJZA 2JT5A 3USNA 3L0VA 1OS2A 4XCTA 5D1UA 4PKUA 2W13A 4GR8A 3RTSA 4AXQA 3EHYA 1OM6A 4A7BA 4AUOA 1C7KA 3I7IA 1G4KA 1SLMA 1DMTA 3Q2HA 1MNCA 3AIGA 1D5JA 3KECA 1MMRA 2W0DA 4JQGA 1C3IA 2YB9A 1BUVM 1JH1A 3LIKA 4GWNA 4XM7A 1SATA 1QUAA 1ATLA 1QICA 4H30A 3G5CA 1CGEA 1G49A 3B92A 1OMJA 1HFSA 1O0QA 4L6TA 4GWMA 1GO7P 1JKYA 2X3AA 4IN9A 3LIRA 2RJQA 1B3DA 1CGLA 2MZEA 1AF0A 1SMPA 1HTDA 4L63A 2OXZA 1GE5A 3AYKA 5D1SA 4ZR5A 3F15A 1SU3A 1PWQA 3HB2P 966CA 1HV5A 2WOAA 1FM1A 5D1TA 2USNA 1ASTA 1C8TA 2OZRA 5B5OA 1BQOA 3EWJA 3O64A 3KWVC 2EROA 1Q3AA 2TCLA 1JAPA 4L19A 2XS4A 2I47A 2MLSA 4PKSA 1D7XA 1GXDA 3LKAA 3Q2GA 2PJTA 1CIZA 2N8RA 2CKIA 2WO9A 4G9LA 1IACA 1SLNA 1R1IA 3AYUA 2W12A 2OVXA 3ZVSA 1ZS0A 4JA1A 1JK3A 2CLTA 1ZXVA 2OW9A 3B8ZA 3TS4A 1XFVA 2OY2A 3F16A 1JAOA 3N2UA 1K7QA 2YIGA 1OM7A 1MMQA 3G42A 2DDFA 1FLSA 1RM8A 3KHIA 3LUNA 1UEAA 1PWPA 4FXQA 1G05A 1USNA 1KUIA 2DW2A 5LABA 3LUMA 2FV9A 1G12A 4PKVA 2RJPA 1Y0VA 3RTTA 5BOYA 1KAPP 1A86A 1G9KA 2DDYA 2KRJA 1CXVA 4PKWA 4H84A 2W14A 3WV3A 1D8MA 4GF1A 4J4MA 1IADA 2J0TA 4XM6A 4H3XA 2MLRA 3DPFA 2OY4A 3KEJA 1AKLA 1ZP5A 5CZMA 3LJGA 2QPJA 3F19A 5H8XA 1KUGA 4H2EA 5BOTA 3DNGA 3ZUKA 1AYKA 2L0RA 1I76A 1GE6A 1KUFA 1QJJA 1BKCA 1BIWA 1D8FA 1QJIA 3KMCA 2K9CA 4IJOA 1HFCA 1KBCA 3WV1A 4H1QA 4XM8A 1BQQM 3K7LA 5CUHA 1O0TA 1QIBA 4AYKA 5I0LA 5JMYA 1PWUA 1BKCI 2OXUA 2SRTA 4A3WA 1CGFA 4ILWD 2JSDA 2O3EA 3I7GA 1XUCA 5D7WA 3LK8A 3ZXHA 4GR0A 1MMPA 4AIGA 4WKEA 5I43A 3TT4A 2XS3A 3LE9A 2V4BA 1JJ9A 1HOVA 3F1AA 3VTGA 1CQRA 4DPEA 1QIAA 1ROSA 2O36A 5L79A 3OHOA 1XURA 2A8HA 4DF9A 3TSKA 1R1HA 1JAQA 3L0TA 3HBUP 1JIZA 4ON1A 3HDAP
chains in the Genus database with same CATH superfamily
1GKCA 1I73A 3O2XA 5L7FA 1BZSA 3LQBA 3TVCA 2DW0A 5CXAA 1IAAA 1ND1A 2E3XA 1UMSA 1UMTA 4JP4A 1J7NA 4Q1LA 1FBLA 3EDIA 3DL1A 4DV8A 3BA0A 2OW0A 3EDGA 4I03A 2OVZA 2X3CA 3EHXA 1Z3JA 1GO8P 4WKIA 5B5PA 1R55A 4R3VA 1IAGA 1BKCE 2Y6CA 1DTHA 3F18A 4IUWA 2OW2A 2ERQA 5D2BA 4EFSA 5I12A 1BUDA 4FVLA 5BPAA 2JT6A 2J83A 3GBOA 4GUYA 3LEAA 2JNPA 3DPEA 3DSLA 1ZTQA 1OO9A 1XFZA 3K7NA 4WF6A 4FXYP 3LILA 3LMCA 456CA 1MMBA 1K7GA 2Y6DA 3U1RA 3LGPA 2D1NA 4JIJA 1XFWA 1PWWA 3KRYA 4XBHA 1UTZA 3WV2A 1ZVXA 3P24A 3LQ0A 3SHIA 5I3MA 1R54A 3HYGA 3EDZA 1CK7A 4FU4A 1RMZA 2Z2DA 1YOUA 1JANA 1WNIA 1Y93A 1Y8JA 2DW1A 3ELMA 1IAEA 3P1VA 1YCMA 3HY7A 3HBVP 4QKZA 1JIWP 2W15A 1I1IP 4HMAA 1BSWA 1K7IA 1KUKA 1GKDA 4PKTA 3E8RA 3KMEA 2K2GA 1YQYA 3EDHA 2FV5A 3N2VA 1XFYA 3KEKA 1UTTA 1EAKA 3UVCA 1XUDA 4WZVA 1L6JA 1XFXA 2AYKA 2X7MA 3B2ZA 3DWBA 1EUBA 1GE7A 1H71P 4CTHA 1KUHA 2AIGP 2WO8A 2MZIA 4JPAA 5D3CA 5I4OA 2JIHA 2D1OA 1XFUA 1YP1A 2OI0A 3HDBA 2OXWA 2POJA 4PKQA 3CKIA 3NX7A 1HY7A 5I2ZA 1CAQA 4HX3A 1PWVA 4G0DA 4WK7A 2E2DA 3DTIA 4I35A 1BM6A 3MA2A 3VI1A 4H76A 1R1JA 1ZXCA 2HU6A 3HY9A 2X3BA 4H49A 3V96B 4PKRA 2MZHA 1EB6A 1A85A 2OW1A 1B8YA 3F17A 4DD8A 1S4BP 830CA 1SRPA 1OM8A 4GQLA 1IABA 2ERPA 4GR3A 1OS9A 4H82A 3LJTA 3OHLA 3LJZA 2JT5A 3USNA 3L0VA 1OS2A 4XCTA 5D1UA 4PKUA 2W13A 4GR8A 3RTSA 1XM5A 4AXQA 3EHYA 1OM6A 4A7BA 4AUOA 1C7KA 1XAXA 3I7IA 4L7AA 1G4KA 1SLMA 1DMTA 3Q2HA 1MNCA 3AIGA 1D5JA 3KECA 1MMRA 2W0DA 4JQGA 1C3IA 2YB9A 1BUVM 1JH1A 3LIKA 4GWNA 4XM7A 1SATA 1QUAA 1ATLA 1QICA 4H30A 3G5CA 1CGEA 1G49A 3B92A 1OMJA 1HFSA 1O0QA 4L6TA 4GWMA 1GO7P 1JKYA 2X3AA 4IN9A 3LIRA 2RJQA 1B3DA 1CGLA 2MZEA 1AF0A 1SMPA 1HTDA 4L63A 1OZ9A 2OXZA 1GE5A 3AYKA 5D1SA 4ZR5A 3F15A 1SU3A 1PWQA 3HB2P 966CA 1HV5A 2WOAA 1FM1A 5D1TA 2USNA 1ASTA 1C8TA 2OZRA 5B5OA 1BQOA 3EWJA 3O64A 3KWVC 2EROA 1Q3AA 2TCLA 1JAPA 4L19A 2XS4A 2I47A 2MLSA 4PKSA 1D7XA 1GXDA 3LKAA 3Q2GA 2PJTA 1CIZA 2N8RA 2CKIA 2WO9A 4G9LA 1IACA 1SLNA 1R1IA 3AYUA 2W12A 2OVXA 3ZVSA 1ZS0A 4JA1A 1JK3A 2CLTA 1ZXVA 2OW9A 3B8ZA 3TS4A 1XFVA 2OY2A 3F16A 1JAOA 3N2UA 1K7QA 2YIGA 1OM7A 1MMQA 3G42A 2DDFA 1FLSA 1RM8A 3KHIA 3LUNA 1UEAA 1PWPA 4FXQA 1G05A 1USNA 1KUIA 2DW2A 5LABA 3LUMA 2FV9A 1G12A 4PKVA 2RJPA 1Y0VA 3RTTA 5BOYA 1KAPP 1A86A 1G9KA 2DDYA 2KRJA 1CXVA 4PKWA 4H84A 2W14A 3WV3A 1D8MA 4GF1A 4J4MA 1IADA 2J0TA 4XM6A 4H3XA 2MLRA 3DPFA 2OY4A 3KEJA 1AKLA 1ZP5A 5CZMA 3LJGA 2QPJA 3F19A 5H8XA 1KUGA 4H2EA 5BOTA 3DNGA 3ZUKA 1AYKA 2L0RA 1I76A 1GE6A 1KUFA 1QJJA 1BKCA 1BIWA 1D8FA 1QJIA 3KMCA 2K9CA 4IJOA 1HFCA 1KBCA 3WV1A 4H1QA 4XM8A 1BQQM 3K7LA 5CUHA 3DTEA 1O0TA 1QIBA 4AYKA 5I0LA 5JMYA 2YUFA 1TVIA 1PWUA 1BKCI 2OXUA 2SRTA 4A3WA 1CGFA 4ILWD 2JSDA 2O3EA 3I7GA 1XUCA 5D7WA 3LK8A 3ZXHA 4GR0A 1MMPA 4AIGA 4WKEA 5I43A 3DTKA 3TT4A 2XS3A 3LE9A 2V4BA 1JJ9A 1HOVA 3F1AA 3VTGA 1CQRA 4DPEA 1QIAA 1ROSA 2O36A 5L79A 3OHOA 1XURA 2A8HA 4DF9A 3TSKA 1R1HA 1JAQA 3L0TA 3HBUP 1JIZA 4ON1A 3HDAP
chains in the Genus database with same CATH topology
1GKCA 1I73A 3O2XA 5L7FA 1BZSA 3LQBA 3TVCA 2DW0A 5CXAA 1IAAA 1ND1A 2E3XA 1UMSA 1UMTA 4JP4A 1J7NA 4Q1LA 1FBLA 3EDIA 3DL1A 4DV8A 3BA0A 2OW0A 3EDGA 4I03A 2OVZA 2X3CA 3EHXA 1Z3JA 1GO8P 4WKIA 5B5PA 1R55A 4R3VA 1IAGA 1BKCE 2Y6CA 1DTHA 3F18A 4IUWA 2OW2A 2ERQA 5D2BA 4EFSA 5I12A 1BUDA 4FVLA 5BPAA 2JT6A 2J83A 3GBOA 4GUYA 3LEAA 2JNPA 3DPEA 3DSLA 1ZTQA 1OO9A 1XFZA 3K7NA 4WF6A 4FXYP 3LILA 3LMCA 456CA 1MMBA 1K7GA 2Y6DA 3U1RA 3LGPA 2D1NA 4JIJA 1XFWA 1PWWA 3KRYA 4XBHA 1UTZA 3WV2A 1ZVXA 3P24A 3LQ0A 3SHIA 5I3MA 1R54A 3HYGA 3EDZA 1CK7A 4FU4A 1RMZA 2Z2DA 1YOUA 1JANA 1WNIA 1Y93A 1Y8JA 2DW1A 3ELMA 1IAEA 3P1VA 1YCMA 3HY7A 3HBVP 4QKZA 1JIWP 2W15A 1I1IP 4HMAA 1BSWA 1K7IA 1KUKA 1GKDA 4PKTA 3E8RA 3KMEA 2K2GA 1YQYA 3EDHA 2FV5A 3N2VA 1XFYA 3KEKA 1UTTA 1EAKA 3UVCA 1XUDA 4WZVA 1L6JA 1XFXA 2AYKA 2X7MA 3B2ZA 3DWBA 1EUBA 1GE7A 1H71P 4CTHA 1KUHA 2AIGP 2WO8A 2MZIA 4JPAA 5D3CA 5I4OA 2JIHA 2D1OA 1XFUA 1YP1A 2OI0A 3HDBA 2OXWA 2POJA 4PKQA 3CKIA 3NX7A 1HY7A 5I2ZA 1CAQA 4HX3A 1PWVA 4G0DA 4WK7A 2E2DA 3DTIA 4I35A 1BM6A 3MA2A 3VI1A 4H76A 1R1JA 1ZXCA 2HU6A 3HY9A 2X3BA 4H49A 3V96B 4PKRA 2MZHA 1EB6A 1A85A 2OW1A 1B8YA 3F17A 4DD8A 1S4BP 830CA 1SRPA 1OM8A 4GQLA 1IABA 2ERPA 4GR3A 1OS9A 4H82A 3LJTA 3OHLA 3LJZA 2JT5A 3USNA 3L0VA 1OS2A 4XCTA 5D1UA 4PKUA 2W13A 4GR8A 3RTSA 4AXQA 3EHYA 1OM6A 4A7BA 4AUOA 1C7KA 3I7IA 4L7AA 1G4KA 1SLMA 1DMTA 3Q2HA 1MNCA 3AIGA 1D5JA 3KECA 1MMRA 2W0DA 4JQGA 1C3IA 2YB9A 1BUVM 1JH1A 3LIKA 4GWNA 4XM7A 1SATA 1QUAA 1ATLA 1QICA 4H30A 3G5CA 1CGEA 1G49A 3B92A 1OMJA 1HFSA 1O0QA 4L6TA 4GWMA 1GO7P 1JKYA 2X3AA 4IN9A 3LIRA 2RJQA 1B3DA 1CGLA 2MZEA 1AF0A 1SMPA 1HTDA 4L63A 2OXZA 1GE5A 3AYKA 5D1SA 4ZR5A 3F15A 1SU3A 1PWQA 3HB2P 966CA 1HV5A 2WOAA 1FM1A 5D1TA 2USNA 1ASTA 1C8TA 2OZRA 5B5OA 1BQOA 3EWJA 3O64A 3KWVC 2EROA 1Q3AA 2TCLA 1JAPA 4L19A 2XS4A 2I47A 2MLSA 4PKSA 1D7XA 1GXDA 3LKAA 3Q2GA 2PJTA 1CIZA 2N8RA 2CKIA 2WO9A 4G9LA 1IACA 1SLNA 1R1IA 3AYUA 2W12A 2OVXA 3ZVSA 1ZS0A 4JA1A 1JK3A 2CLTA 1ZXVA 2OW9A 3B8ZA 3TS4A 1XFVA 2OY2A 3F16A 1JAOA 3N2UA 1K7QA 2YIGA 1OM7A 1MMQA 3G42A 2DDFA 1FLSA 1RM8A 3KHIA 3LUNA 1UEAA 1PWPA 4FXQA 1G05A 1USNA 1KUIA 2DW2A 5LABA 3LUMA 2FV9A 1G12A 4PKVA 2RJPA 1Y0VA 3RTTA 5BOYA 1KAPP 1A86A 1G9KA 2DDYA 2KRJA 1CXVA 4PKWA 4H84A 2W14A 3WV3A 1D8MA 4GF1A 4J4MA 1IADA 2J0TA 4XM6A 4H3XA 2MLRA 3DPFA 2OY4A 3KEJA 1AKLA 1ZP5A 5CZMA 3LJGA 2QPJA 3F19A 5H8XA 1KUGA 4H2EA 5BOTA 3DNGA 3ZUKA 1AYKA 2L0RA 1I76A 1GE6A 1KUFA 1QJJA 1BKCA 1BIWA 1D8FA 1QJIA 3KMCA 2K9CA 4IJOA 1HFCA 1KBCA 3WV1A 4H1QA 4XM8A 1BQQM 3K7LA 5CUHA 3DTEA 1O0TA 1QIBA 4AYKA 5I0LA 5JMYA 2YUFA 1PWUA 1BKCI 2OXUA 2SRTA 4A3WA 1CGFA 4ILWD 2JSDA 2O3EA 3I7GA 1XUCA 5D7WA 3LK8A 3ZXHA 4GR0A 1MMPA 4AIGA 4WKEA 5I43A 3DTKA 3TT4A 2XS3A 3LE9A 2V4BA 1JJ9A 1HOVA 3F1AA 3VTGA 1CQRA 4DPEA 1QIAA 1ROSA 2O36A 5L79A 3OHOA 1XURA 2A8HA 4DF9A 3TSKA 1R1HA 1JAQA 3L0TA 3HBUP 1JIZA 4ON1A 3HDAP
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GKC A;  1I73 A;  3O2X A;  5L7F A;  1BZS A;  3LQB A;  3TVC A;  2DW0 A;  5CXA A;  1IAA A;  1ND1 A;  2E3X A;  1UMS A;  1UMT A;  4JP4 A;  1J7N A;  4Q1L A;  1FBL A;  3EDI A;  3DL1 A;  4DV8 A;  3BA0 A;  2OW0 A;  3EDG A;  4I03 A;  2OVZ A;  2X3C A;  3EHX A;  1Z3J A;  1GO8 P;  4WKI A;  5B5P A;  1R55 A;  4R3V A;  1IAG A;  1BKC E;  2Y6C A;  1DTH A;  3F18 A;  4IUW A;  2OW2 A;  2ERQ A;  5D2B A;  4EFS A;  5I12 A;  1BUD A;  4FVL A;  5BPA A;  2JT6 A;  2J83 A;  3GBO A;  4GUY A;  3LEA A;  2JNP A;  3DPE A;  3DSL A;  1ZTQ A;  1OO9 A;  1XFZ A;  3K7N A;  4WF6 A;  4FXY P;  3LIL A;  3LMC A;  456C A;  1MMB A;  1K7G A;  2Y6D A;  3U1R A;  3LGP A;  2D1N A;  4JIJ A;  1XFW A;  1PWW A;  3KRY A;  4XBH A;  1UTZ A;  3WV2 A;  1ZVX A;  3P24 A;  3LQ0 A;  3SHI A;  5I3M A;  1R54 A;  3HYG A;  3EDZ A;  1CK7 A;  4FU4 A;  1RMZ A;  2Z2D A;  1YOU A;  1JAN A;  1WNI A;  1Y93 A;  1Y8J A;  2DW1 A;  3ELM A;  1IAE A;  3P1V A;  1YCM A;  3HY7 A;  3HBV P;  4QKZ A;  1JIW P;  2W15 A;  1I1I P;  4HMA A;  1BSW A;  1K7I A;  1KUK A;  1GKD A;  4PKT A;  3E8R A;  3KME A;  2K2G A;  1YQY A;  3EDH A;  2FV5 A;  3N2V A;  1XFY A;  3KEK A;  1UTT A;  1EAK A;  3UVC A;  1XUD A;  4WZV A;  1L6J A;  1XFX A;  2AYK A;  2X7M A;  3B2Z A;  3DWB A;  1EUB A;  1GE7 A;  1H71 P;  4CTH A;  1KUH A;  2AIG P;  2WO8 A;  2MZI A;  4JPA A;  5D3C A;  5I4O A;  2JIH A;  2D1O A;  1XFU A;  1YP1 A;  2OI0 A;  3HDB A;  2OXW A;  2POJ A;  4PKQ A;  3CKI A;  3NX7 A;  1HY7 A;  5I2Z A;  1CAQ A;  4HX3 A;  1PWV A;  4G0D A;  4WK7 A;  2E2D A;  4I35 A;  1BM6 A;  3MA2 A;  3VI1 A;  4H76 A;  1R1J A;  1ZXC A;  2HU6 A;  3HY9 A;  2X3B A;  4H49 A;  3V96 B;  4PKR A;  2MZH A;  1EB6 A;  1A85 A;  2OW1 A;  1B8Y A;  3F17 A;  4DD8 A;  1S4B P;  830C A;  1SRP A;  1OM8 A;  4GQL A;  1IAB A;  2ERP A;  4GR3 A;  1OS9 A;  4H82 A;  3LJT A;  3OHL A;  3LJZ A;  2JT5 A;  3USN A;  3L0V A;  1OS2 A;  4XCT A;  5D1U A;  4PKU A;  2W13 A;  4GR8 A;  3RTS A;  4AXQ A;  3EHY A;  1OM6 A;  4A7B A;  4AUO A;  1C7K A;  3I7I A;  1G4K A;  1SLM A;  1DMT A;  3Q2H A;  1MNC A;  3AIG A;  1D5J A;  3KEC A;  1MMR A;  2W0D A;  4JQG A;  1C3I A;  2YB9 A;  1BUV M;  1JH1 A;  3LIK A;  4GWN A;  4XM7 A;  1SAT A;  1QUA A;  1ATL A;  1QIC A;  4H30 A;  3G5C A;  1CGE A;  1G49 A;  3B92 A;  1OMJ A;  1HFS A;  1O0Q A;  4L6T A;  4GWM A;  1GO7 P;  1JKY A;  2X3A A;  4IN9 A;  3LIR A;  2RJQ A;  1B3D A;  1CGL A;  2MZE A;  1AF0 A;  1SMP A;  1HTD A;  4L63 A;  2OXZ A;  1GE5 A;  3AYK A;  5D1S A;  4ZR5 A;  3F15 A;  1SU3 A;  1PWQ A;  3HB2 P;  966C A;  1HV5 A;  2WOA A;  1FM1 A;  5D1T A;  2USN A;  1AST A;  1C8T A;  2OZR A;  5B5O A;  1BQO A;  3EWJ A;  3O64 A;  3KWV C;  2ERO A;  1Q3A A;  2TCL A;  1JAP A;  4L19 A;  2XS4 A;  2I47 A;  2MLS A;  4PKS A;  1D7X A;  1GXD A;  3LKA A;  3Q2G A;  2PJT A;  1CIZ A;  2N8R A;  2CKI A;  2WO9 A;  4G9L A;  1IAC A;  1SLN A;  1R1I A;  3AYU A;  2W12 A;  2OVX A;  3ZVS A;  1ZS0 A;  4JA1 A;  1JK3 A;  2CLT A;  1ZXV A;  2OW9 A;  3B8Z A;  3TS4 A;  1XFV A;  2OY2 A;  3F16 A;  1JAO A;  3N2U A;  1K7Q A;  2YIG A;  1OM7 A;  1MMQ A;  3G42 A;  2DDF A;  1FLS A;  1RM8 A;  3KHI A;  3LUN A;  1UEA A;  1PWP A;  4FXQ A;  1G05 A;  1USN A;  1KUI A;  2DW2 A;  5LAB A;  3LUM A;  2FV9 A;  1G12 A;  4PKV A;  2RJP A;  1Y0V A;  3RTT A;  5BOY A;  1KAP P;  1A86 A;  1G9K A;  2DDY A;  2KRJ A;  1CXV A;  4PKW A;  4H84 A;  2W14 A;  3WV3 A;  1D8M A;  4GF1 A;  4J4M A;  1IAD A;  2J0T A;  4XM6 A;  4H3X A;  2MLR A;  3DPF A;  2OY4 A;  3KEJ A;  1AKL A;  1ZP5 A;  5CZM A;  3LJG A;  2QPJ A;  3F19 A;  5H8X A;  1KUG A;  4H2E A;  5BOT A;  3DNG A;  3ZUK A;  1AYK A;  2L0R A;  1I76 A;  1GE6 A;  1KUF A;  1QJJ A;  1BKC A;  1BIW A;  1D8F A;  1QJI A;  3KMC A;  2K9C A;  4IJO A;  1HFC A;  1KBC A;  3WV1 A;  4H1Q A;  4XM8 A;  1BQQ M;  3K7L A;  5CUH A;  1O0T A;  1QIB A;  4AYK A;  5I0L A;  5JMY A;  1PWU A;  1BKC I;  2OXU A;  2SRT A;  4A3W A;  1CGF A;  4ILW D;  2JSD A;  2O3E A;  3I7G A;  1XUC A;  5D7W A;  3LK8 A;  3ZXH A;  4GR0 A;  1MMP A;  4AIG A;  4WKE A;  5I43 A;  3TT4 A;  2XS3 A;  3LE9 A;  2V4B A;  1JJ9 A;  1HOV A;  3F1A A;  3VTG A;  1CQR A;  4DPE A;  1QIA A;  1ROS A;  2O36 A;  5L79 A;  3OHO A;  1XUR A;  2A8H A;  4DF9 A;  3TSK A;  1R1H A;  1JAQ A;  3L0T A;  3HBU P;  1JIZ A;  4ON1 A;  3HDA P; 
#chains in the Genus database with same CATH topology
 1GKC A;  1I73 A;  3O2X A;  5L7F A;  1BZS A;  3LQB A;  3TVC A;  2DW0 A;  5CXA A;  1IAA A;  1ND1 A;  2E3X A;  1UMS A;  1UMT A;  4JP4 A;  1J7N A;  4Q1L A;  1FBL A;  3EDI A;  3DL1 A;  4DV8 A;  3BA0 A;  2OW0 A;  3EDG A;  4I03 A;  2OVZ A;  2X3C A;  3EHX A;  1Z3J A;  1GO8 P;  4WKI A;  5B5P A;  1R55 A;  4R3V A;  1IAG A;  1BKC E;  2Y6C A;  1DTH A;  3F18 A;  4IUW A;  2OW2 A;  2ERQ A;  5D2B A;  4EFS A;  5I12 A;  1BUD A;  4FVL A;  5BPA A;  2JT6 A;  2J83 A;  3GBO A;  4GUY A;  3LEA A;  2JNP A;  3DPE A;  3DSL A;  1ZTQ A;  1OO9 A;  1XFZ A;  3K7N A;  4WF6 A;  4FXY P;  3LIL A;  3LMC A;  456C A;  1MMB A;  1K7G A;  2Y6D A;  3U1R A;  3LGP A;  2D1N A;  4JIJ A;  1XFW A;  1PWW A;  3KRY A;  4XBH A;  1UTZ A;  3WV2 A;  1ZVX A;  3P24 A;  3LQ0 A;  3SHI A;  5I3M A;  1R54 A;  3HYG A;  3EDZ A;  1CK7 A;  4FU4 A;  1RMZ A;  2Z2D A;  1YOU A;  1JAN A;  1WNI A;  1Y93 A;  1Y8J A;  2DW1 A;  3ELM A;  1IAE A;  3P1V A;  1YCM A;  3HY7 A;  3HBV P;  4QKZ A;  1JIW P;  2W15 A;  1I1I P;  4HMA A;  1BSW A;  1K7I A;  1KUK A;  1GKD A;  4PKT A;  3E8R A;  3KME A;  2K2G A;  1YQY A;  3EDH A;  2FV5 A;  3N2V A;  1XFY A;  3KEK A;  1UTT A;  1EAK A;  3UVC A;  1XUD A;  4WZV A;  1L6J A;  1XFX A;  2AYK A;  2X7M A;  3B2Z A;  3DWB A;  1EUB A;  1GE7 A;  1H71 P;  4CTH A;  1KUH A;  2AIG P;  2WO8 A;  2MZI A;  4JPA A;  5D3C A;  5I4O A;  2JIH A;  2D1O A;  1XFU A;  1YP1 A;  2OI0 A;  3HDB A;  2OXW A;  2POJ A;  4PKQ A;  3CKI A;  3NX7 A;  1HY7 A;  5I2Z A;  1CAQ A;  4HX3 A;  1PWV A;  4G0D A;  4WK7 A;  2E2D A;  3DTI A;  4I35 A;  1BM6 A;  3MA2 A;  3VI1 A;  4H76 A;  1R1J A;  1ZXC A;  2HU6 A;  3HY9 A;  2X3B A;  4H49 A;  3V96 B;  4PKR A;  2MZH A;  1EB6 A;  1A85 A;  2OW1 A;  1B8Y A;  3F17 A;  4DD8 A;  1S4B P;  830C A;  1SRP A;  1OM8 A;  4GQL A;  1IAB A;  2ERP A;  4GR3 A;  1OS9 A;  4H82 A;  3LJT A;  3OHL A;  3LJZ A;  2JT5 A;  3USN A;  3L0V A;  1OS2 A;  4XCT A;  5D1U A;  4PKU A;  2W13 A;  4GR8 A;  3RTS A;  1XM5 A;  4AXQ A;  3EHY A;  1OM6 A;  4A7B A;  4AUO A;  1C7K A;  1XAX A;  3I7I A;  4L7A A;  1G4K A;  1SLM A;  1DMT A;  3Q2H A;  1MNC A;  3AIG A;  1D5J A;  3KEC A;  1MMR A;  2W0D A;  4JQG A;  1C3I A;  2YB9 A;  1BUV M;  1JH1 A;  3LIK A;  4GWN A;  4XM7 A;  1SAT A;  1QUA A;  1ATL A;  1QIC A;  4H30 A;  3G5C A;  1CGE A;  1G49 A;  3B92 A;  1OMJ A;  1HFS A;  1O0Q A;  4L6T A;  4GWM A;  1GO7 P;  1JKY A;  2X3A A;  4IN9 A;  3LIR A;  2RJQ A;  1B3D A;  1CGL A;  2MZE A;  1AF0 A;  1SMP A;  1HTD A;  4L63 A;  1OZ9 A;  2OXZ A;  1GE5 A;  3AYK A;  5D1S A;  4ZR5 A;  3F15 A;  1SU3 A;  1PWQ A;  3HB2 P;  966C A;  1HV5 A;  2WOA A;  1FM1 A;  5D1T A;  2USN A;  1AST A;  1C8T A;  2OZR A;  5B5O A;  1BQO A;  3EWJ A;  3O64 A;  3KWV C;  2ERO A;  1Q3A A;  2TCL A;  1JAP A;  4L19 A;  2XS4 A;  2I47 A;  2MLS A;  4PKS A;  1D7X A;  1GXD A;  3LKA A;  3Q2G A;  2PJT A;  1CIZ A;  2N8R A;  2CKI A;  2WO9 A;  4G9L A;  1IAC A;  1SLN A;  1R1I A;  3AYU A;  2W12 A;  2OVX A;  3ZVS A;  1ZS0 A;  4JA1 A;  1JK3 A;  2CLT A;  1ZXV A;  2OW9 A;  3B8Z A;  3TS4 A;  1XFV A;  2OY2 A;  3F16 A;  1JAO A;  3N2U A;  1K7Q A;  2YIG A;  1OM7 A;  1MMQ A;  3G42 A;  2DDF A;  1FLS A;  1RM8 A;  3KHI A;  3LUN A;  1UEA A;  1PWP A;  4FXQ A;  1G05 A;  1USN A;  1KUI A;  2DW2 A;  5LAB A;  3LUM A;  2FV9 A;  1G12 A;  4PKV A;  2RJP A;  1Y0V A;  3RTT A;  5BOY A;  1KAP P;  1A86 A;  1G9K A;  2DDY A;  2KRJ A;  1CXV A;  4PKW A;  4H84 A;  2W14 A;  3WV3 A;  1D8M A;  4GF1 A;  4J4M A;  1IAD A;  2J0T A;  4XM6 A;  4H3X A;  2MLR A;  3DPF A;  2OY4 A;  3KEJ A;  1AKL A;  1ZP5 A;  5CZM A;  3LJG A;  2QPJ A;  3F19 A;  5H8X A;  1KUG A;  4H2E A;  5BOT A;  3DNG A;  3ZUK A;  1AYK A;  2L0R A;  1I76 A;  1GE6 A;  1KUF A;  1QJJ A;  1BKC A;  1BIW A;  1D8F A;  1QJI A;  3KMC A;  2K9C A;  4IJO A;  1HFC A;  1KBC A;  3WV1 A;  4H1Q A;  4XM8 A;  1BQQ M;  3K7L A;  5CUH A;  3DTE A;  1O0T A;  1QIB A;  4AYK A;  5I0L A;  5JMY A;  2YUF A;  1TVI A;  1PWU A;  1BKC I;  2OXU A;  2SRT A;  4A3W A;  1CGF A;  4ILW D;  2JSD A;  2O3E A;  3I7G A;  1XUC A;  5D7W A;  3LK8 A;  3ZXH A;  4GR0 A;  1MMP A;  4AIG A;  4WKE A;  5I43 A;  3DTK A;  3TT4 A;  2XS3 A;  3LE9 A;  2V4B A;  1JJ9 A;  1HOV A;  3F1A A;  3VTG A;  1CQR A;  4DPE A;  1QIA A;  1ROS A;  2O36 A;  5L79 A;  3OHO A;  1XUR A;  2A8H A;  4DF9 A;  3TSK A;  1R1H A;  1JAQ A;  3L0T A;  3HBU P;  1JIZ A;  4ON1 A;  3HDA P; 
#chains in the Genus database with same CATH homology
 1GKC A;  1I73 A;  3O2X A;  5L7F A;  1BZS A;  3LQB A;  3TVC A;  2DW0 A;  5CXA A;  1IAA A;  1ND1 A;  2E3X A;  1UMS A;  1UMT A;  4JP4 A;  1J7N A;  4Q1L A;  1FBL A;  3EDI A;  3DL1 A;  4DV8 A;  3BA0 A;  2OW0 A;  3EDG A;  4I03 A;  2OVZ A;  2X3C A;  3EHX A;  1Z3J A;  1GO8 P;  4WKI A;  5B5P A;  1R55 A;  4R3V A;  1IAG A;  1BKC E;  2Y6C A;  1DTH A;  3F18 A;  4IUW A;  2OW2 A;  2ERQ A;  5D2B A;  4EFS A;  5I12 A;  1BUD A;  4FVL A;  5BPA A;  2JT6 A;  2J83 A;  3GBO A;  4GUY A;  3LEA A;  2JNP A;  3DPE A;  3DSL A;  1ZTQ A;  1OO9 A;  1XFZ A;  3K7N A;  4WF6 A;  4FXY P;  3LIL A;  3LMC A;  456C A;  1MMB A;  1K7G A;  2Y6D A;  3U1R A;  3LGP A;  2D1N A;  4JIJ A;  1XFW A;  1PWW A;  3KRY A;  4XBH A;  1UTZ A;  3WV2 A;  1ZVX A;  3P24 A;  3LQ0 A;  3SHI A;  5I3M A;  1R54 A;  3HYG A;  3EDZ A;  1CK7 A;  4FU4 A;  1RMZ A;  2Z2D A;  1YOU A;  1JAN A;  1WNI A;  1Y93 A;  1Y8J A;  2DW1 A;  3ELM A;  1IAE A;  3P1V A;  1YCM A;  3HY7 A;  3HBV P;  4QKZ A;  1JIW P;  2W15 A;  1I1I P;  4HMA A;  1BSW A;  1K7I A;  1KUK A;  1GKD A;  4PKT A;  3E8R A;  3KME A;  2K2G A;  1YQY A;  3EDH A;  2FV5 A;  3N2V A;  1XFY A;  3KEK A;  1UTT A;  1EAK A;  3UVC A;  1XUD A;  4WZV A;  1L6J A;  1XFX A;  2AYK A;  2X7M A;  3B2Z A;  3DWB A;  1EUB A;  1GE7 A;  1H71 P;  4CTH A;  1KUH A;  2AIG P;  2WO8 A;  2MZI A;  4JPA A;  5D3C A;  5I4O A;  2JIH A;  2D1O A;  1XFU A;  1YP1 A;  2OI0 A;  3HDB A;  2OXW A;  2POJ A;  4PKQ A;  3CKI A;  3NX7 A;  1HY7 A;  5I2Z A;  1CAQ A;  4HX3 A;  1PWV A;  4G0D A;  4WK7 A;  2E2D A;  3DTI A;  4I35 A;  1BM6 A;  3MA2 A;  3VI1 A;  4H76 A;  1R1J A;  1ZXC A;  2HU6 A;  3HY9 A;  2X3B A;  4H49 A;  3V96 B;  4PKR A;  2MZH A;  1EB6 A;  1A85 A;  2OW1 A;  1B8Y A;  3F17 A;  4DD8 A;  1S4B P;  830C A;  1SRP A;  1OM8 A;  4GQL A;  1IAB A;  2ERP A;  4GR3 A;  1OS9 A;  4H82 A;  3LJT A;  3OHL A;  3LJZ A;  2JT5 A;  3USN A;  3L0V A;  1OS2 A;  4XCT A;  5D1U A;  4PKU A;  2W13 A;  4GR8 A;  3RTS A;  4AXQ A;  3EHY A;  1OM6 A;  4A7B A;  4AUO A;  1C7K A;  3I7I A;  4L7A A;  1G4K A;  1SLM A;  1DMT A;  3Q2H A;  1MNC A;  3AIG A;  1D5J A;  3KEC A;  1MMR A;  2W0D A;  4JQG A;  1C3I A;  2YB9 A;  1BUV M;  1JH1 A;  3LIK A;  4GWN A;  4XM7 A;  1SAT A;  1QUA A;  1ATL A;  1QIC A;  4H30 A;  3G5C A;  1CGE A;  1G49 A;  3B92 A;  1OMJ A;  1HFS A;  1O0Q A;  4L6T A;  4GWM A;  1GO7 P;  1JKY A;  2X3A A;  4IN9 A;  3LIR A;  2RJQ A;  1B3D A;  1CGL A;  2MZE A;  1AF0 A;  1SMP A;  1HTD A;  4L63 A;  2OXZ A;  1GE5 A;  3AYK A;  5D1S A;  4ZR5 A;  3F15 A;  1SU3 A;  1PWQ A;  3HB2 P;  966C A;  1HV5 A;  2WOA A;  1FM1 A;  5D1T A;  2USN A;  1AST A;  1C8T A;  2OZR A;  5B5O A;  1BQO A;  3EWJ A;  3O64 A;  3KWV C;  2ERO A;  1Q3A A;  2TCL A;  1JAP A;  4L19 A;  2XS4 A;  2I47 A;  2MLS A;  4PKS A;  1D7X A;  1GXD A;  3LKA A;  3Q2G A;  2PJT A;  1CIZ A;  2N8R A;  2CKI A;  2WO9 A;  4G9L A;  1IAC A;  1SLN A;  1R1I A;  3AYU A;  2W12 A;  2OVX A;  3ZVS A;  1ZS0 A;  4JA1 A;  1JK3 A;  2CLT A;  1ZXV A;  2OW9 A;  3B8Z A;  3TS4 A;  1XFV A;  2OY2 A;  3F16 A;  1JAO A;  3N2U A;  1K7Q A;  2YIG A;  1OM7 A;  1MMQ A;  3G42 A;  2DDF A;  1FLS A;  1RM8 A;  3KHI A;  3LUN A;  1UEA A;  1PWP A;  4FXQ A;  1G05 A;  1USN A;  1KUI A;  2DW2 A;  5LAB A;  3LUM A;  2FV9 A;  1G12 A;  4PKV A;  2RJP A;  1Y0V A;  3RTT A;  5BOY A;  1KAP P;  1A86 A;  1G9K A;  2DDY A;  2KRJ A;  1CXV A;  4PKW A;  4H84 A;  2W14 A;  3WV3 A;  1D8M A;  4GF1 A;  4J4M A;  1IAD A;  2J0T A;  4XM6 A;  4H3X A;  2MLR A;  3DPF A;  2OY4 A;  3KEJ A;  1AKL A;  1ZP5 A;  5CZM A;  3LJG A;  2QPJ A;  3F19 A;  5H8X A;  1KUG A;  4H2E A;  5BOT A;  3DNG A;  3ZUK A;  1AYK A;  2L0R A;  1I76 A;  1GE6 A;  1KUF A;  1QJJ A;  1BKC A;  1BIW A;  1D8F A;  1QJI A;  3KMC A;  2K9C A;  4IJO A;  1HFC A;  1KBC A;  3WV1 A;  4H1Q A;  4XM8 A;  1BQQ M;  3K7L A;  5CUH A;  3DTE A;  1O0T A;  1QIB A;  4AYK A;  5I0L A;  5JMY A;  2YUF A;  1PWU A;  1BKC I;  2OXU A;  2SRT A;  4A3W A;  1CGF A;  4ILW D;  2JSD A;  2O3E A;  3I7G A;  1XUC A;  5D7W A;  3LK8 A;  3ZXH A;  4GR0 A;  1MMP A;  4AIG A;  4WKE A;  5I43 A;  3DTK A;  3TT4 A;  2XS3 A;  3LE9 A;  2V4B A;  1JJ9 A;  1HOV A;  3F1A A;  3VTG A;  1CQR A;  4DPE A;  1QIA A;  1ROS A;  2O36 A;  5L79 A;  3OHO A;  1XUR A;  2A8H A;  4DF9 A;  3TSK A;  1R1H A;  1JAQ A;  3L0T A;  3HBU P;  1JIZ A;  4ON1 A;  3HDA P; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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