2FV9A

Crystal structure of tace in complex with jmv 390-1
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
258
structure length
254
Chain Sequence
PDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYGGSPHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Stabilization of the autoproteolysis of TNF-alpha converting enzyme (TACE) results in a novel crystal form suitable for structure-based drug design studies.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords ADAM 17
total genus 81
structure length 254
sequence length 258
chains with identical sequence B
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2006-01-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 2fv9A00
3LGPA 3HYGA 4PKSA 2MZEA 1BUVM 1CXVA 1CK7A 3Q2GA 2OVZA 1OM8A 1GE6A 1QUAA 2DW1A 2EROA 2OI0A 1CGFA 1Z3JA 5BOTA 1OS9A 4WKEA 1R1HA 1GXDA 1BSWA 1JK3A 2WO8A 4GF1A 1G12A 1BQQM 1IAEA 4I03A 2MLRA 1JKYA 4DF9A 1QIBA 3ELMA 2I47A 2DW2A 5I0LA 4DV8A 2Z2DA 1ZP5A 3B2ZA 3G42A 4DD8A 4JIJA 3KMCA 830CA 3EDGA 1OM7A 1PWVA 1ZS0A 3EWJA 2OXUA 1IACA 3DWBA 1SU3A 2OW2A 4FXQA 1OM6A 2Y6DA 1HY7A 2PJTA 4ILWD 2V4BA 2K2GA 2K9CA 3V96B 1K7QA 3HDBA 1KUHA 4JP4A 1KUKA 3MA2A 1AYKA 3F17A 4G0DA 1XFYA 5I4OA 3ZXHA 1SATA 3LK8A 3WV2A 1JIWP 2OZRA 3EDHA 1ROSA 3HY9A 2JSDA 3K7LA 4IN9A 3F16A 4AIGA 4H2EA 2OY2A 1B8YA 4GUYA 1OS2A 2WOAA 4GWNA 3DPFA 4PKUA 2W13A 1Y0VA 1XURA 2MLSA 4H30A 1SMPA 1Y93A 3L0VA 3KWVC 1ZXVA 4H82A 3LMCA 3DL1A 2CLTA 2HU6A 1GO8P 1JANA 1GE7A 3F19A 2JT6A 4AYKA 2E3XA 1OMJA 3LEAA 4R3VA 1JAQA 3LJGA 3HB2P 1BQOA 1XUDA 4AXQA 3TVCA 2JIHA 2OW9A 3NX7A 2FV9A 1SLNA 1O0QA 1EAKA 4HX3A 5H8XA 1XFUA 1HV5A 1G4KA 2J0TA 2L0RA 1JIZA 1BKCI 2RJPA 456CA 3LJTA 1I73A 3AYKA 4L19A 2YB9A 1YOUA 2USNA 4XBHA 1BZSA 2TCLA 3P1VA 1UMSA 1CAQA 5CZMA 3KHIA 1IAGA 1OO9A 2N8RA 2MZHA 1GKDA 1KUGA 3EDIA 4H1QA 1ATLA 1Y8JA 3HY7A 4GR0A 2CKIA 1EUBA 5D1UA 4L6TA 1JAPA 1FBLA 1K7IA 1XFWA 5D7WA 3WV3A 3LQBA 4GR8A 2OXZA 4H3XA 4XM6A 4XCTA 1O0TA 1BIWA 1ZTQA 4PKVA 1JJ9A 1HOVA 1SLMA 4HMAA 3HBUP 1KUIA 1UTZA 3B92A 1HFSA 3Q2HA 4G9LA 4WZVA 2D1NA 1HFCA 1G05A 2KRJA 5L7FA 1H71P 2W15A 4GWMA 1JAOA 3E8RA 1C8TA 4XM8A 2X3BA 1DTHA 1A86A 1D8FA 2JNPA 1RM8A 3HDAP 4GR3A 3KECA 1YQYA 3N2UA 3EDZA 3GBOA 1R1JA 1CGEA 3LIKA 2AYKA 4FVLA 3DSLA 4A3WA 2W14A 1R1IA 1MMRA 1IAAA 2DDFA 3TT4A 5D1SA 2OW0A 3RTSA 5I43A 3K7NA 1EB6A 3I7GA 1HTDA 1UTTA 1R54A 3LQ0A 4IJOA 1C3IA 4AUOA 3KEJA 1FLSA 1ZVXA 3HBVP 1JH1A 5I12A 2WO9A 5LABA 5B5PA 2X3CA 1QJJA 3LE9A 1MMBA 5L79A 2DDYA 3I7IA 2DW0A 4XM7A 1PWQA 4IUWA 1XFZA 966CA 1C7KA 3F1AA 4Q1LA 1G49A 1GE5A 3OHLA 2J83A 3F18A 1GKCA 4JQGA 2ERPA 3ZUKA 2SRTA 3LILA 1MMPA 4QKZA 3LUMA 1IABA 4L63A 3BA0A 1AKLA 1D8MA 2Y6CA 1G9KA 5JMYA 5CXAA 1Q3AA 3AIGA 1FM1A 3EHXA 3OHOA 1D5JA 1D7XA 1YP1A 2AIGP 1ZXCA 1CQRA 3O64A 1KBCA 2D1OA 3DNGA 3EHYA 1IADA 1J7NA 1QICA 1ASTA 2XS4A 1BUDA 1YCMA 3UVCA 4WKIA 1KAPP 2O3EA 2QPJA 3F15A 3USNA 4PKRA 1I1IP 1L6JA 2A8HA 2JT5A 4JA1A 5BOYA 2X3AA 5D1TA 2XS3A 2FV5A 1ND1A 3TS4A 4WK7A 3TSKA 3WV1A 4PKQA 3SHIA 1R55A 1QJIA 5D3CA 4H84A 5D2BA 3DPEA 4EFSA 4H76A 3RTTA 1MNCA 2RJQA 1XFVA 3ZVSA 1MMQA 4ON1A 4FXYP 1B3DA 4DPEA 4ZR5A 2OW1A 3CKIA 1RMZA 2W0DA 1BKCE 3P24A 4WF6A 1CIZA 4H49A 3KEKA 3KMEA 4A7BA 2OVXA 2MZIA 1XFXA 3U1RA 1BKCA 5BPAA 3N2VA 1BM6A 1K7GA 5B5OA 3LKAA 1UEAA 1WNIA 2OY4A 3AYUA 2ERQA 1AF0A 3G5CA 3L0TA 3LUNA 1QIAA 2E2DA 2X7MA 1PWPA 2O36A 5I2ZA 1PWUA 3VI1A 3KRYA 2OXWA 2W12A 1XUCA 1PWWA 4JPAA 1GO7P 4PKTA 3VTGA 2POJA 4PKWA 4FU4A 1I76A 1CGLA 4I35A 4J4MA 3O2XA 3LIRA 1UMTA 1A85A 3LJZA 3B8ZA 1USNA 5I3MA 1S4BP 1SRPA 5CUHA 4CTHA 1DMTA 2YIGA 1KUFA 4GQLA
chains in the Genus database with same CATH superfamily
3LGPA 3HYGA 4PKSA 2MZEA 1BUVM 1CXVA 1CK7A 3Q2GA 2OVZA 1OM8A 1GE6A 1QUAA 2DW1A 2EROA 2OI0A 1CGFA 1Z3JA 5BOTA 1OS9A 4WKEA 1R1HA 1GXDA 1BSWA 1JK3A 2WO8A 4GF1A 1G12A 1BQQM 1IAEA 4I03A 2MLRA 1JKYA 4DF9A 1QIBA 3ELMA 2I47A 2DW2A 5I0LA 4DV8A 2Z2DA 1ZP5A 3B2ZA 3G42A 4DD8A 4JIJA 3KMCA 830CA 3EDGA 1OM7A 1PWVA 1ZS0A 3EWJA 2OXUA 1IACA 3DWBA 1SU3A 2OW2A 4FXQA 1OM6A 2Y6DA 1HY7A 2PJTA 4ILWD 2V4BA 2K2GA 2K9CA 3V96B 1K7QA 3HDBA 1KUHA 4JP4A 1KUKA 3MA2A 1AYKA 3F17A 4G0DA 1XFYA 5I4OA 3ZXHA 1SATA 3LK8A 3WV2A 1JIWP 2OZRA 3EDHA 1ROSA 3HY9A 2JSDA 3K7LA 4IN9A 3F16A 4AIGA 4H2EA 2OY2A 1B8YA 4GUYA 1OS2A 3DTIA 2WOAA 4GWNA 3DPFA 4PKUA 2W13A 1Y0VA 1XURA 2MLSA 4H30A 1SMPA 1Y93A 3L0VA 3KWVC 1ZXVA 4H82A 3LMCA 3DL1A 2CLTA 2HU6A 1GO8P 1JANA 1GE7A 3F19A 2JT6A 4AYKA 2E3XA 1OMJA 3LEAA 4R3VA 1JAQA 3LJGA 3HB2P 1BQOA 1XUDA 4AXQA 3TVCA 2JIHA 2OW9A 3NX7A 2FV9A 1SLNA 1O0QA 1EAKA 4HX3A 5H8XA 1XFUA 1HV5A 1G4KA 2J0TA 2L0RA 1JIZA 1OZ9A 1BKCI 2RJPA 456CA 3LJTA 1I73A 3AYKA 4L19A 2YB9A 1YOUA 2USNA 4XBHA 1BZSA 2TCLA 3P1VA 1UMSA 1CAQA 5CZMA 3DTKA 1XM5A 1IAGA 3KHIA 1OO9A 2N8RA 2MZHA 1GKDA 1KUGA 3EDIA 4H1QA 1ATLA 1Y8JA 3HY7A 4GR0A 2CKIA 1EUBA 5D1UA 4L6TA 1JAPA 1FBLA 1K7IA 1XFWA 5D7WA 3WV3A 3LQBA 4GR8A 2OXZA 4H3XA 4XM6A 4XCTA 1O0TA 1BIWA 1ZTQA 4PKVA 1JJ9A 1HOVA 1SLMA 4HMAA 3HBUP 1KUIA 1UTZA 3B92A 1HFSA 3Q2HA 4G9LA 4WZVA 2D1NA 1HFCA 1G05A 2KRJA 5L7FA 1H71P 2W15A 4GWMA 1JAOA 3E8RA 1C8TA 4XM8A 2X3BA 1DTHA 1A86A 1D8FA 2JNPA 1RM8A 3HDAP 4GR3A 3KECA 1TVIA 1YQYA 3EDZA 3GBOA 3N2UA 1R1JA 1CGEA 3LIKA 2AYKA 4FVLA 3DSLA 4A3WA 2W14A 1R1IA 1MMRA 1IAAA 2DDFA 3TT4A 5D1SA 2OW0A 3RTSA 5I43A 3K7NA 1EB6A 3I7GA 1HTDA 1UTTA 1R54A 3LQ0A 4IJOA 1C3IA 4AUOA 3KEJA 1FLSA 1ZVXA 3HBVP 1JH1A 5I12A 2WO9A 5LABA 5B5PA 2X3CA 1QJJA 3LE9A 1MMBA 5L79A 2DDYA 3I7IA 2DW0A 4XM7A 1PWQA 4IUWA 1XFZA 966CA 1C7KA 3F1AA 4Q1LA 1G49A 1GE5A 3OHLA 2J83A 3F18A 1GKCA 4JQGA 2ERPA 3ZUKA 4L7AA 2SRTA 3LILA 1MMPA 4QKZA 3LUMA 1IABA 4L63A 3BA0A 1AKLA 1D8MA 2Y6CA 1G9KA 5JMYA 5CXAA 1Q3AA 3AIGA 1FM1A 3EHXA 3OHOA 1D5JA 1D7XA 1XAXA 1YP1A 1ZXCA 2AIGP 1CQRA 3O64A 1KBCA 2D1OA 3DNGA 3EHYA 1IADA 1J7NA 1QICA 1ASTA 2XS4A 1BUDA 1YCMA 3UVCA 4WKIA 1KAPP 2O3EA 2QPJA 3F15A 3USNA 4PKRA 1I1IP 1L6JA 2A8HA 2JT5A 4JA1A 5BOYA 2X3AA 5D1TA 2XS3A 2FV5A 1ND1A 3TS4A 4WK7A 3TSKA 3WV1A 4PKQA 3SHIA 1R55A 1QJIA 5D3CA 4H84A 5D2BA 3DPEA 4EFSA 4H76A 3RTTA 1MNCA 2RJQA 1XFVA 3ZVSA 1MMQA 4ON1A 2YUFA 4FXYP 1B3DA 4DPEA 4ZR5A 2OW1A 3CKIA 1RMZA 2W0DA 1BKCE 3P24A 4WF6A 1CIZA 4H49A 3KEKA 3KMEA 4A7BA 2OVXA 2MZIA 1XFXA 3U1RA 1BKCA 5BPAA 3N2VA 1BM6A 1K7GA 5B5OA 3LKAA 1UEAA 1WNIA 2OY4A 3AYUA 2ERQA 1AF0A 3G5CA 3L0TA 3LUNA 1QIAA 2E2DA 3DTEA 2X7MA 1PWPA 2O36A 5I2ZA 1PWUA 3VI1A 3KRYA 2OXWA 2W12A 1XUCA 1PWWA 4JPAA 1GO7P 4PKTA 3VTGA 2POJA 4PKWA 4FU4A 1I76A 1CGLA 4I35A 4J4MA 3O2XA 3LIRA 1UMTA 1A85A 3LJZA 3B8ZA 1USNA 5I3MA 1S4BP 1SRPA 5CUHA 4CTHA 1DMTA 2YIGA 1KUFA 4GQLA
chains in the Genus database with same CATH topology
3LGPA 3HYGA 4PKSA 2MZEA 1BUVM 1CXVA 1CK7A 3Q2GA 2OVZA 1OM8A 1GE6A 1QUAA 2DW1A 2EROA 2OI0A 1CGFA 1Z3JA 5BOTA 1OS9A 4WKEA 1R1HA 1GXDA 1BSWA 1JK3A 2WO8A 4GF1A 1G12A 1BQQM 1IAEA 4I03A 2MLRA 1JKYA 4DF9A 1QIBA 3ELMA 2I47A 2DW2A 5I0LA 4DV8A 2Z2DA 1ZP5A 3B2ZA 3G42A 4DD8A 4JIJA 3KMCA 830CA 3EDGA 1OM7A 1PWVA 1ZS0A 3EWJA 2OXUA 1IACA 3DWBA 1SU3A 2OW2A 4FXQA 1OM6A 2Y6DA 1HY7A 2PJTA 4ILWD 2V4BA 2K2GA 2K9CA 3V96B 1K7QA 3HDBA 1KUHA 4JP4A 1KUKA 3MA2A 1AYKA 3F17A 4G0DA 1XFYA 5I4OA 3ZXHA 1SATA 3LK8A 3WV2A 1JIWP 2OZRA 3EDHA 1ROSA 3HY9A 2JSDA 3K7LA 4IN9A 3F16A 4AIGA 4H2EA 2OY2A 1B8YA 4GUYA 1OS2A 3DTIA 2WOAA 4GWNA 3DPFA 4PKUA 2W13A 1Y0VA 1XURA 2MLSA 4H30A 1SMPA 1Y93A 3L0VA 3KWVC 1ZXVA 4H82A 3LMCA 3DL1A 2CLTA 2HU6A 1GO8P 1JANA 1GE7A 3F19A 2JT6A 4AYKA 2E3XA 1OMJA 3LEAA 4R3VA 1JAQA 3LJGA 3HB2P 1BQOA 1XUDA 4AXQA 3TVCA 2JIHA 2OW9A 3NX7A 2FV9A 1SLNA 1O0QA 1EAKA 4HX3A 5H8XA 1XFUA 1HV5A 1G4KA 2J0TA 2L0RA 1JIZA 1BKCI 2RJPA 456CA 3LJTA 1I73A 3AYKA 4L19A 2YB9A 1YOUA 2USNA 4XBHA 1BZSA 2TCLA 3P1VA 1UMSA 1CAQA 5CZMA 3DTKA 3KHIA 1IAGA 1OO9A 2N8RA 2MZHA 1GKDA 1KUGA 3EDIA 4H1QA 1ATLA 1Y8JA 3HY7A 4GR0A 2CKIA 1EUBA 5D1UA 4L6TA 1JAPA 1FBLA 1K7IA 1XFWA 5D7WA 3WV3A 3LQBA 4GR8A 2OXZA 4H3XA 4XM6A 4XCTA 1O0TA 1BIWA 1ZTQA 4PKVA 1JJ9A 1HOVA 1SLMA 4HMAA 3HBUP 1KUIA 1UTZA 3B92A 1HFSA 3Q2HA 4G9LA 4WZVA 2D1NA 1HFCA 1G05A 2KRJA 5L7FA 1H71P 2W15A 4GWMA 1JAOA 3E8RA 1C8TA 4XM8A 2X3BA 1DTHA 1A86A 1D8FA 2JNPA 1RM8A 3HDAP 4GR3A 3KECA 1YQYA 3N2UA 3EDZA 3GBOA 1R1JA 1CGEA 3LIKA 2AYKA 4FVLA 3DSLA 4A3WA 2W14A 1R1IA 1MMRA 1IAAA 2DDFA 3TT4A 5D1SA 2OW0A 3RTSA 5I43A 3K7NA 1EB6A 3I7GA 1HTDA 1UTTA 1R54A 3LQ0A 4IJOA 1C3IA 4AUOA 3KEJA 1FLSA 1ZVXA 3HBVP 1JH1A 5I12A 2WO9A 5LABA 5B5PA 2X3CA 1QJJA 3LE9A 1MMBA 5L79A 2DDYA 3I7IA 2DW0A 4XM7A 1PWQA 4IUWA 1XFZA 966CA 1C7KA 3F1AA 4Q1LA 1G49A 1GE5A 3OHLA 2J83A 3F18A 1GKCA 4JQGA 2ERPA 3ZUKA 4L7AA 2SRTA 3LILA 1MMPA 4QKZA 3LUMA 1IABA 4L63A 3BA0A 1AKLA 1D8MA 2Y6CA 1G9KA 5JMYA 5CXAA 1Q3AA 3AIGA 1FM1A 3EHXA 3OHOA 1D5JA 1D7XA 1YP1A 2AIGP 1ZXCA 1CQRA 3O64A 1KBCA 2D1OA 3DNGA 3EHYA 1IADA 1J7NA 1QICA 1ASTA 2XS4A 1BUDA 1YCMA 3UVCA 4WKIA 1KAPP 2O3EA 2QPJA 3F15A 3USNA 4PKRA 1I1IP 1L6JA 2A8HA 2JT5A 4JA1A 5BOYA 2X3AA 5D1TA 2XS3A 2FV5A 1ND1A 3TS4A 4WK7A 3TSKA 3WV1A 4PKQA 3SHIA 1R55A 1QJIA 5D3CA 4H84A 5D2BA 3DPEA 4EFSA 4H76A 3RTTA 1MNCA 2RJQA 1XFVA 3ZVSA 1MMQA 4ON1A 2YUFA 4FXYP 1B3DA 4DPEA 4ZR5A 2OW1A 3CKIA 1RMZA 2W0DA 1BKCE 3P24A 4WF6A 1CIZA 4H49A 3KEKA 3KMEA 4A7BA 2OVXA 2MZIA 1XFXA 3U1RA 1BKCA 5BPAA 3N2VA 1BM6A 1K7GA 5B5OA 3LKAA 1UEAA 1WNIA 2OY4A 3AYUA 2ERQA 1AF0A 3G5CA 3L0TA 3LUNA 1QIAA 2E2DA 3DTEA 2X7MA 1PWPA 2O36A 5I2ZA 1PWUA 3VI1A 3KRYA 2OXWA 2W12A 1XUCA 1PWWA 4JPAA 1GO7P 4PKTA 3VTGA 2POJA 4PKWA 4FU4A 1I76A 1CGLA 4I35A 4J4MA 3O2XA 3LIRA 1UMTA 1A85A 3LJZA 3B8ZA 1USNA 5I3MA 1S4BP 1SRPA 5CUHA 4CTHA 1DMTA 2YIGA 1KUFA 4GQLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LGP A;  3HYG A;  4PKS A;  2MZE A;  1BUV M;  1CXV A;  1CK7 A;  3Q2G A;  2OVZ A;  1OM8 A;  1GE6 A;  1QUA A;  2DW1 A;  2ERO A;  2OI0 A;  1CGF A;  1Z3J A;  5BOT A;  1OS9 A;  4WKE A;  1R1H A;  1GXD A;  1BSW A;  1JK3 A;  2WO8 A;  4GF1 A;  1G12 A;  1BQQ M;  1IAE A;  4I03 A;  2MLR A;  1JKY A;  4DF9 A;  1QIB A;  3ELM A;  2I47 A;  2DW2 A;  5I0L A;  4DV8 A;  2Z2D A;  1ZP5 A;  3B2Z A;  3G42 A;  4DD8 A;  4JIJ A;  3KMC A;  830C A;  3EDG A;  1OM7 A;  1PWV A;  1ZS0 A;  3EWJ A;  2OXU A;  1IAC A;  3DWB A;  1SU3 A;  2OW2 A;  4FXQ A;  1OM6 A;  2Y6D A;  1HY7 A;  2PJT A;  4ILW D;  2V4B A;  2K2G A;  2K9C A;  3V96 B;  1K7Q A;  3HDB A;  1KUH A;  4JP4 A;  1KUK A;  3MA2 A;  1AYK A;  3F17 A;  4G0D A;  1XFY A;  5I4O A;  3ZXH A;  1SAT A;  3LK8 A;  3WV2 A;  1JIW P;  2OZR A;  3EDH A;  1ROS A;  3HY9 A;  2JSD A;  3K7L A;  4IN9 A;  3F16 A;  4AIG A;  4H2E A;  2OY2 A;  1B8Y A;  4GUY A;  1OS2 A;  2WOA A;  4GWN A;  3DPF A;  4PKU A;  2W13 A;  1Y0V A;  1XUR A;  2MLS A;  4H30 A;  1SMP A;  1Y93 A;  3L0V A;  3KWV C;  1ZXV A;  4H82 A;  3LMC A;  3DL1 A;  2CLT A;  2HU6 A;  1GO8 P;  1JAN A;  1GE7 A;  3F19 A;  2JT6 A;  4AYK A;  2E3X A;  1OMJ A;  3LEA A;  4R3V A;  1JAQ A;  3LJG A;  3HB2 P;  1BQO A;  1XUD A;  4AXQ A;  3TVC A;  2JIH A;  2OW9 A;  3NX7 A;  2FV9 A;  1SLN A;  1O0Q A;  1EAK A;  4HX3 A;  5H8X A;  1XFU A;  1HV5 A;  1G4K A;  2J0T A;  2L0R A;  1JIZ A;  1BKC I;  2RJP A;  456C A;  3LJT A;  1I73 A;  3AYK A;  4L19 A;  2YB9 A;  1YOU A;  2USN A;  4XBH A;  1BZS A;  2TCL A;  3P1V A;  1UMS A;  1CAQ A;  5CZM A;  3KHI A;  1IAG A;  1OO9 A;  2N8R A;  2MZH A;  1GKD A;  1KUG A;  3EDI A;  4H1Q A;  1ATL A;  1Y8J A;  3HY7 A;  4GR0 A;  2CKI A;  1EUB A;  5D1U A;  4L6T A;  1JAP A;  1FBL A;  1K7I A;  1XFW A;  5D7W A;  3WV3 A;  3LQB A;  4GR8 A;  2OXZ A;  4H3X A;  4XM6 A;  4XCT A;  1O0T A;  1BIW A;  1ZTQ A;  4PKV A;  1JJ9 A;  1HOV A;  1SLM A;  4HMA A;  3HBU P;  1KUI A;  1UTZ A;  3B92 A;  1HFS A;  3Q2H A;  4G9L A;  4WZV A;  2D1N A;  1HFC A;  1G05 A;  2KRJ A;  5L7F A;  1H71 P;  2W15 A;  4GWM A;  1JAO A;  3E8R A;  1C8T A;  4XM8 A;  2X3B A;  1DTH A;  1A86 A;  1D8F A;  2JNP A;  1RM8 A;  3HDA P;  4GR3 A;  3KEC A;  1YQY A;  3N2U A;  3EDZ A;  3GBO A;  1R1J A;  1CGE A;  3LIK A;  2AYK A;  4FVL A;  3DSL A;  4A3W A;  2W14 A;  1R1I A;  1MMR A;  1IAA A;  2DDF A;  3TT4 A;  5D1S A;  2OW0 A;  3RTS A;  5I43 A;  3K7N A;  1EB6 A;  3I7G A;  1HTD A;  1UTT A;  1R54 A;  3LQ0 A;  4IJO A;  1C3I A;  4AUO A;  3KEJ A;  1FLS A;  1ZVX A;  3HBV P;  1JH1 A;  5I12 A;  2WO9 A;  5LAB A;  5B5P A;  2X3C A;  1QJJ A;  3LE9 A;  1MMB A;  5L79 A;  2DDY A;  3I7I A;  2DW0 A;  4XM7 A;  1PWQ A;  4IUW A;  1XFZ A;  966C A;  1C7K A;  3F1A A;  4Q1L A;  1G49 A;  1GE5 A;  3OHL A;  2J83 A;  3F18 A;  1GKC A;  4JQG A;  2ERP A;  3ZUK A;  2SRT A;  3LIL A;  1MMP A;  4QKZ A;  3LUM A;  1IAB A;  4L63 A;  3BA0 A;  1AKL A;  1D8M A;  2Y6C A;  1G9K A;  5JMY A;  5CXA A;  1Q3A A;  3AIG A;  1FM1 A;  3EHX A;  3OHO A;  1D5J A;  1D7X A;  1YP1 A;  2AIG P;  1ZXC A;  1CQR A;  3O64 A;  1KBC A;  2D1O A;  3DNG A;  3EHY A;  1IAD A;  1J7N A;  1QIC A;  1AST A;  2XS4 A;  1BUD A;  1YCM A;  3UVC A;  4WKI A;  1KAP P;  2O3E A;  2QPJ A;  3F15 A;  3USN A;  4PKR A;  1I1I P;  1L6J A;  2A8H A;  2JT5 A;  4JA1 A;  5BOY A;  2X3A A;  5D1T A;  2XS3 A;  2FV5 A;  1ND1 A;  3TS4 A;  4WK7 A;  3TSK A;  3WV1 A;  4PKQ A;  3SHI A;  1R55 A;  1QJI A;  5D3C A;  4H84 A;  5D2B A;  3DPE A;  4EFS A;  4H76 A;  3RTT A;  1MNC A;  2RJQ A;  1XFV A;  3ZVS A;  1MMQ A;  4ON1 A;  4FXY P;  1B3D A;  4DPE A;  4ZR5 A;  2OW1 A;  3CKI A;  1RMZ A;  2W0D A;  1BKC E;  3P24 A;  4WF6 A;  1CIZ A;  4H49 A;  3KEK A;  3KME A;  4A7B A;  2OVX A;  2MZI A;  1XFX A;  3U1R A;  1BKC A;  5BPA A;  3N2V A;  1BM6 A;  1K7G A;  5B5O A;  3LKA A;  1UEA A;  1WNI A;  2OY4 A;  3AYU A;  2ERQ A;  1AF0 A;  3G5C A;  3L0T A;  3LUN A;  1QIA A;  2E2D A;  2X7M A;  1PWP A;  2O36 A;  5I2Z A;  1PWU A;  3VI1 A;  3KRY A;  2OXW A;  2W12 A;  1XUC A;  1PWW A;  4JPA A;  1GO7 P;  4PKT A;  3VTG A;  2POJ A;  4PKW A;  4FU4 A;  1I76 A;  1CGL A;  4I35 A;  4J4M A;  3O2X A;  3LIR A;  1UMT A;  1A85 A;  3LJZ A;  3B8Z A;  1USN A;  5I3M A;  1S4B P;  1SRP A;  5CUH A;  4CTH A;  1DMT A;  2YIG A;  1KUF A;  4GQL A; 
#chains in the Genus database with same CATH topology
 3LGP A;  3HYG A;  4PKS A;  2MZE A;  1BUV M;  1CXV A;  1CK7 A;  3Q2G A;  2OVZ A;  1OM8 A;  1GE6 A;  1QUA A;  2DW1 A;  2ERO A;  2OI0 A;  1CGF A;  1Z3J A;  5BOT A;  1OS9 A;  4WKE A;  1R1H A;  1GXD A;  1BSW A;  1JK3 A;  2WO8 A;  4GF1 A;  1G12 A;  1BQQ M;  1IAE A;  4I03 A;  2MLR A;  1JKY A;  4DF9 A;  1QIB A;  3ELM A;  2I47 A;  2DW2 A;  5I0L A;  4DV8 A;  2Z2D A;  1ZP5 A;  3B2Z A;  3G42 A;  4DD8 A;  4JIJ A;  3KMC A;  830C A;  3EDG A;  1OM7 A;  1PWV A;  1ZS0 A;  3EWJ A;  2OXU A;  1IAC A;  3DWB A;  1SU3 A;  2OW2 A;  4FXQ A;  1OM6 A;  2Y6D A;  1HY7 A;  2PJT A;  4ILW D;  2V4B A;  2K2G A;  2K9C A;  3V96 B;  1K7Q A;  3HDB A;  1KUH A;  4JP4 A;  1KUK A;  3MA2 A;  1AYK A;  3F17 A;  4G0D A;  1XFY A;  5I4O A;  3ZXH A;  1SAT A;  3LK8 A;  3WV2 A;  1JIW P;  2OZR A;  3EDH A;  1ROS A;  3HY9 A;  2JSD A;  3K7L A;  4IN9 A;  3F16 A;  4AIG A;  4H2E A;  2OY2 A;  1B8Y A;  4GUY A;  1OS2 A;  3DTI A;  2WOA A;  4GWN A;  3DPF A;  4PKU A;  2W13 A;  1Y0V A;  1XUR A;  2MLS A;  4H30 A;  1SMP A;  1Y93 A;  3L0V A;  3KWV C;  1ZXV A;  4H82 A;  3LMC A;  3DL1 A;  2CLT A;  2HU6 A;  1GO8 P;  1JAN A;  1GE7 A;  3F19 A;  2JT6 A;  4AYK A;  2E3X A;  1OMJ A;  3LEA A;  4R3V A;  1JAQ A;  3LJG A;  3HB2 P;  1BQO A;  1XUD A;  4AXQ A;  3TVC A;  2JIH A;  2OW9 A;  3NX7 A;  2FV9 A;  1SLN A;  1O0Q A;  1EAK A;  4HX3 A;  5H8X A;  1XFU A;  1HV5 A;  1G4K A;  2J0T A;  2L0R A;  1JIZ A;  1OZ9 A;  1BKC I;  2RJP A;  456C A;  3LJT A;  1I73 A;  3AYK A;  4L19 A;  2YB9 A;  1YOU A;  2USN A;  4XBH A;  1BZS A;  2TCL A;  3P1V A;  1UMS A;  1CAQ A;  5CZM A;  3DTK A;  1XM5 A;  1IAG A;  3KHI A;  1OO9 A;  2N8R A;  2MZH A;  1GKD A;  1KUG A;  3EDI A;  4H1Q A;  1ATL A;  1Y8J A;  3HY7 A;  4GR0 A;  2CKI A;  1EUB A;  5D1U A;  4L6T A;  1JAP A;  1FBL A;  1K7I A;  1XFW A;  5D7W A;  3WV3 A;  3LQB A;  4GR8 A;  2OXZ A;  4H3X A;  4XM6 A;  4XCT A;  1O0T A;  1BIW A;  1ZTQ A;  4PKV A;  1JJ9 A;  1HOV A;  1SLM A;  4HMA A;  3HBU P;  1KUI A;  1UTZ A;  3B92 A;  1HFS A;  3Q2H A;  4G9L A;  4WZV A;  2D1N A;  1HFC A;  1G05 A;  2KRJ A;  5L7F A;  1H71 P;  2W15 A;  4GWM A;  1JAO A;  3E8R A;  1C8T A;  4XM8 A;  2X3B A;  1DTH A;  1A86 A;  1D8F A;  2JNP A;  1RM8 A;  3HDA P;  4GR3 A;  3KEC A;  1TVI A;  1YQY A;  3EDZ A;  3GBO A;  3N2U A;  1R1J A;  1CGE A;  3LIK A;  2AYK A;  4FVL A;  3DSL A;  4A3W A;  2W14 A;  1R1I A;  1MMR A;  1IAA A;  2DDF A;  3TT4 A;  5D1S A;  2OW0 A;  3RTS A;  5I43 A;  3K7N A;  1EB6 A;  3I7G A;  1HTD A;  1UTT A;  1R54 A;  3LQ0 A;  4IJO A;  1C3I A;  4AUO A;  3KEJ A;  1FLS A;  1ZVX A;  3HBV P;  1JH1 A;  5I12 A;  2WO9 A;  5LAB A;  5B5P A;  2X3C A;  1QJJ A;  3LE9 A;  1MMB A;  5L79 A;  2DDY A;  3I7I A;  2DW0 A;  4XM7 A;  1PWQ A;  4IUW A;  1XFZ A;  966C A;  1C7K A;  3F1A A;  4Q1L A;  1G49 A;  1GE5 A;  3OHL A;  2J83 A;  3F18 A;  1GKC A;  4JQG A;  2ERP A;  3ZUK A;  4L7A A;  2SRT A;  3LIL A;  1MMP A;  4QKZ A;  3LUM A;  1IAB A;  4L63 A;  3BA0 A;  1AKL A;  1D8M A;  2Y6C A;  1G9K A;  5JMY A;  5CXA A;  1Q3A A;  3AIG A;  1FM1 A;  3EHX A;  3OHO A;  1D5J A;  1D7X A;  1XAX A;  1YP1 A;  1ZXC A;  2AIG P;  1CQR A;  3O64 A;  1KBC A;  2D1O A;  3DNG A;  3EHY A;  1IAD A;  1J7N A;  1QIC A;  1AST A;  2XS4 A;  1BUD A;  1YCM A;  3UVC A;  4WKI A;  1KAP P;  2O3E A;  2QPJ A;  3F15 A;  3USN A;  4PKR A;  1I1I P;  1L6J A;  2A8H A;  2JT5 A;  4JA1 A;  5BOY A;  2X3A A;  5D1T A;  2XS3 A;  2FV5 A;  1ND1 A;  3TS4 A;  4WK7 A;  3TSK A;  3WV1 A;  4PKQ A;  3SHI A;  1R55 A;  1QJI A;  5D3C A;  4H84 A;  5D2B A;  3DPE A;  4EFS A;  4H76 A;  3RTT A;  1MNC A;  2RJQ A;  1XFV A;  3ZVS A;  1MMQ A;  4ON1 A;  2YUF A;  4FXY P;  1B3D A;  4DPE A;  4ZR5 A;  2OW1 A;  3CKI A;  1RMZ A;  2W0D A;  1BKC E;  3P24 A;  4WF6 A;  1CIZ A;  4H49 A;  3KEK A;  3KME A;  4A7B A;  2OVX A;  2MZI A;  1XFX A;  3U1R A;  1BKC A;  5BPA A;  3N2V A;  1BM6 A;  1K7G A;  5B5O A;  3LKA A;  1UEA A;  1WNI A;  2OY4 A;  3AYU A;  2ERQ A;  1AF0 A;  3G5C A;  3L0T A;  3LUN A;  1QIA A;  2E2D A;  3DTE A;  2X7M A;  1PWP A;  2O36 A;  5I2Z A;  1PWU A;  3VI1 A;  3KRY A;  2OXW A;  2W12 A;  1XUC A;  1PWW A;  4JPA A;  1GO7 P;  4PKT A;  3VTG A;  2POJ A;  4PKW A;  4FU4 A;  1I76 A;  1CGL A;  4I35 A;  4J4M A;  3O2X A;  3LIR A;  1UMT A;  1A85 A;  3LJZ A;  3B8Z A;  1USN A;  5I3M A;  1S4B P;  1SRP A;  5CUH A;  4CTH A;  1DMT A;  2YIG A;  1KUF A;  4GQL A; 
#chains in the Genus database with same CATH homology
 3LGP A;  3HYG A;  4PKS A;  2MZE A;  1BUV M;  1CXV A;  1CK7 A;  3Q2G A;  2OVZ A;  1OM8 A;  1GE6 A;  1QUA A;  2DW1 A;  2ERO A;  2OI0 A;  1CGF A;  1Z3J A;  5BOT A;  1OS9 A;  4WKE A;  1R1H A;  1GXD A;  1BSW A;  1JK3 A;  2WO8 A;  4GF1 A;  1G12 A;  1BQQ M;  1IAE A;  4I03 A;  2MLR A;  1JKY A;  4DF9 A;  1QIB A;  3ELM A;  2I47 A;  2DW2 A;  5I0L A;  4DV8 A;  2Z2D A;  1ZP5 A;  3B2Z A;  3G42 A;  4DD8 A;  4JIJ A;  3KMC A;  830C A;  3EDG A;  1OM7 A;  1PWV A;  1ZS0 A;  3EWJ A;  2OXU A;  1IAC A;  3DWB A;  1SU3 A;  2OW2 A;  4FXQ A;  1OM6 A;  2Y6D A;  1HY7 A;  2PJT A;  4ILW D;  2V4B A;  2K2G A;  2K9C A;  3V96 B;  1K7Q A;  3HDB A;  1KUH A;  4JP4 A;  1KUK A;  3MA2 A;  1AYK A;  3F17 A;  4G0D A;  1XFY A;  5I4O A;  3ZXH A;  1SAT A;  3LK8 A;  3WV2 A;  1JIW P;  2OZR A;  3EDH A;  1ROS A;  3HY9 A;  2JSD A;  3K7L A;  4IN9 A;  3F16 A;  4AIG A;  4H2E A;  2OY2 A;  1B8Y A;  4GUY A;  1OS2 A;  3DTI A;  2WOA A;  4GWN A;  3DPF A;  4PKU A;  2W13 A;  1Y0V A;  1XUR A;  2MLS A;  4H30 A;  1SMP A;  1Y93 A;  3L0V A;  3KWV C;  1ZXV A;  4H82 A;  3LMC A;  3DL1 A;  2CLT A;  2HU6 A;  1GO8 P;  1JAN A;  1GE7 A;  3F19 A;  2JT6 A;  4AYK A;  2E3X A;  1OMJ A;  3LEA A;  4R3V A;  1JAQ A;  3LJG A;  3HB2 P;  1BQO A;  1XUD A;  4AXQ A;  3TVC A;  2JIH A;  2OW9 A;  3NX7 A;  2FV9 A;  1SLN A;  1O0Q A;  1EAK A;  4HX3 A;  5H8X A;  1XFU A;  1HV5 A;  1G4K A;  2J0T A;  2L0R A;  1JIZ A;  1BKC I;  2RJP A;  456C A;  3LJT A;  1I73 A;  3AYK A;  4L19 A;  2YB9 A;  1YOU A;  2USN A;  4XBH A;  1BZS A;  2TCL A;  3P1V A;  1UMS A;  1CAQ A;  5CZM A;  3DTK A;  3KHI A;  1IAG A;  1OO9 A;  2N8R A;  2MZH A;  1GKD A;  1KUG A;  3EDI A;  4H1Q A;  1ATL A;  1Y8J A;  3HY7 A;  4GR0 A;  2CKI A;  1EUB A;  5D1U A;  4L6T A;  1JAP A;  1FBL A;  1K7I A;  1XFW A;  5D7W A;  3WV3 A;  3LQB A;  4GR8 A;  2OXZ A;  4H3X A;  4XM6 A;  4XCT A;  1O0T A;  1BIW A;  1ZTQ A;  4PKV A;  1JJ9 A;  1HOV A;  1SLM A;  4HMA A;  3HBU P;  1KUI A;  1UTZ A;  3B92 A;  1HFS A;  3Q2H A;  4G9L A;  4WZV A;  2D1N A;  1HFC A;  1G05 A;  2KRJ A;  5L7F A;  1H71 P;  2W15 A;  4GWM A;  1JAO A;  3E8R A;  1C8T A;  4XM8 A;  2X3B A;  1DTH A;  1A86 A;  1D8F A;  2JNP A;  1RM8 A;  3HDA P;  4GR3 A;  3KEC A;  1YQY A;  3N2U A;  3EDZ A;  3GBO A;  1R1J A;  1CGE A;  3LIK A;  2AYK A;  4FVL A;  3DSL A;  4A3W A;  2W14 A;  1R1I A;  1MMR A;  1IAA A;  2DDF A;  3TT4 A;  5D1S A;  2OW0 A;  3RTS A;  5I43 A;  3K7N A;  1EB6 A;  3I7G A;  1HTD A;  1UTT A;  1R54 A;  3LQ0 A;  4IJO A;  1C3I A;  4AUO A;  3KEJ A;  1FLS A;  1ZVX A;  3HBV P;  1JH1 A;  5I12 A;  2WO9 A;  5LAB A;  5B5P A;  2X3C A;  1QJJ A;  3LE9 A;  1MMB A;  5L79 A;  2DDY A;  3I7I A;  2DW0 A;  4XM7 A;  1PWQ A;  4IUW A;  1XFZ A;  966C A;  1C7K A;  3F1A A;  4Q1L A;  1G49 A;  1GE5 A;  3OHL A;  2J83 A;  3F18 A;  1GKC A;  4JQG A;  2ERP A;  3ZUK A;  4L7A A;  2SRT A;  3LIL A;  1MMP A;  4QKZ A;  3LUM A;  1IAB A;  4L63 A;  3BA0 A;  1AKL A;  1D8M A;  2Y6C A;  1G9K A;  5JMY A;  5CXA A;  1Q3A A;  3AIG A;  1FM1 A;  3EHX A;  3OHO A;  1D5J A;  1D7X A;  1YP1 A;  2AIG P;  1ZXC A;  1CQR A;  3O64 A;  1KBC A;  2D1O A;  3DNG A;  3EHY A;  1IAD A;  1J7N A;  1QIC A;  1AST A;  2XS4 A;  1BUD A;  1YCM A;  3UVC A;  4WKI A;  1KAP P;  2O3E A;  2QPJ A;  3F15 A;  3USN A;  4PKR A;  1I1I P;  1L6J A;  2A8H A;  2JT5 A;  4JA1 A;  5BOY A;  2X3A A;  5D1T A;  2XS3 A;  2FV5 A;  1ND1 A;  3TS4 A;  4WK7 A;  3TSK A;  3WV1 A;  4PKQ A;  3SHI A;  1R55 A;  1QJI A;  5D3C A;  4H84 A;  5D2B A;  3DPE A;  4EFS A;  4H76 A;  3RTT A;  1MNC A;  2RJQ A;  1XFV A;  3ZVS A;  1MMQ A;  4ON1 A;  2YUF A;  4FXY P;  1B3D A;  4DPE A;  4ZR5 A;  2OW1 A;  3CKI A;  1RMZ A;  2W0D A;  1BKC E;  3P24 A;  4WF6 A;  1CIZ A;  4H49 A;  3KEK A;  3KME A;  4A7B A;  2OVX A;  2MZI A;  1XFX A;  3U1R A;  1BKC A;  5BPA A;  3N2V A;  1BM6 A;  1K7G A;  5B5O A;  3LKA A;  1UEA A;  1WNI A;  2OY4 A;  3AYU A;  2ERQ A;  1AF0 A;  3G5C A;  3L0T A;  3LUN A;  1QIA A;  2E2D A;  3DTE A;  2X7M A;  1PWP A;  2O36 A;  5I2Z A;  1PWU A;  3VI1 A;  3KRY A;  2OXW A;  2W12 A;  1XUC A;  1PWW A;  4JPA A;  1GO7 P;  4PKT A;  3VTG A;  2POJ A;  4PKW A;  4FU4 A;  1I76 A;  1CGL A;  4I35 A;  4J4M A;  3O2X A;  3LIR A;  1UMT A;  1A85 A;  3LJZ A;  3B8Z A;  1USN A;  5I3M A;  1S4B P;  1SRP A;  5CUH A;  4CTH A;  1DMT A;  2YIG A;  1KUF A;  4GQL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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