2POJA

Nmr solution structure of the inhibitor-free state of macrophage metalloelastase (mmp-12)
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
164
structure length
164
Chain Sequence
FREMPGGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDFHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHAIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution Structure of Inhibitor-Free Human Metalloelastase (MMP-12) Indicates an Internal Conformational Adjustment.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Macrophage metalloelastase
total genus 28
structure length 164
sequence length 164
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2007-04-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 2pojA00
2FV9A 2MZHA 3KEKA 3HBUP 1OO9A 1UMTA 4A3WA 4HX3A 4AYKA 4CTHA 3ELMA 1K7GA 4PKTA 1J7NA 3TSKA 1CXVA 3B8ZA 1XUCA 3AIGA 1I76A 2X7MA 1K7QA 2SRTA 3KWVC 4FXYP 2A8HA 1UMSA 3I7GA 1ZTQA 1UTTA 1CAQA 3KHIA 4H1QA 1RM8A 3DPFA 2J0TA 1G49A 1BZSA 3OHOA 5JMYA 2N8RA 3B2ZA 1BKCI 1C8TA 4H84A 4R3VA 3RTTA 2JNPA 1XUDA 4EFSA 1MMRA 1RMZA 1GO8P 5CUHA 4L19A 2ERPA 3LUMA 1G05A 2Y6DA 1GXDA 4PKUA 3EDIA 2DDYA 3WV1A 1BQOA 4IUWA 1OM6A 1ND1A 2WO9A 2W15A 1JIZA 1HTDA 2OW2A 1WNIA 2MZIA 2JT5A 3EWJA 4AIGA 4GQLA 2AIGP 3I7IA 4I03A 5L7FA 4J4MA 1AYKA 2OW1A 1USNA 1QJJA 1JAQA 1BQQM 2OXZA 2OY2A 3ZVSA 3EHXA 1G12A 4H3XA 1CGEA 1HV5A 1GKCA 4A7BA 4DF9A 4WZVA 2OVZA 1Y0VA 4ZR5A 1AF0A 1MNCA 2OW0A 1MMPA 3G5CA 3HY7A 1IAEA 3K7NA 1Y8JA 3U1RA 4ON1A 1AKLA 2CKIA 3F15A 5I0LA 1OM7A 1KUFA 1QJIA 4GWMA 3VTGA 1XFUA 1O0QA 2OVXA 4GR0A 1CIZA 1SRPA 1EAKA 1KUIA 1KUKA 3EDGA 4JIJA 1DMTA 1R1IA 3LKAA 3P1VA 2X3AA 3E8RA 1YOUA 2OXWA 1JKYA 3LJGA 3LJZA 1R54A 1BSWA 4G9LA 2OI0A 1SU3A 3DSLA 1H71P 2JSDA 4PKQA 4WF6A 1B8YA 2USNA 1KAPP 1ZS0A 4AUOA 1FBLA 1I73A 1KUGA 5D7WA 3BA0A 3ZUKA 1CK7A 2E3XA 1PWVA 2WO8A 1ATLA 1OS9A 2JIHA 4H30A 2YIGA 5D1SA 1XURA 1A86A 2W0DA 3LIRA 2ERQA 4H76A 3O64A 1PWPA 4WKEA 5I4OA 5L79A 1XFVA 5CZMA 1JAPA 1QIBA 4PKWA 4XM7A 2XS3A 2HU6A 3VI1A 1SATA 1G4KA 4GWNA 1CGFA 3KECA 4GUYA 1QUAA 456CA 1XFXA 5D3CA 5B5OA 3LUNA 2DW0A 4QKZA 2MZEA 1OS2A 2OZRA 4GF1A 1CGLA 1D8MA 3KRYA 3NX7A 2QPJA 2Y6CA 4L6TA 4Q1LA 2DW2A 1GKDA 1IABA 1QICA 1MMBA 3HBVP 4HMAA 1D5JA 3LEAA 5LABA 1UEAA 4DPEA 4G0DA 2O36A 3RTSA 1S4BP 3EDZA 4PKRA 1XFWA 1XFYA 1QIAA 2DDFA 2W13A 1Z3JA 4I35A 1B3DA 2PJTA 2Z2DA 4XM6A 3AYUA 3N2UA 2JT6A 3EHYA 4JP4A 3KEJA 4WKIA 3Q2HA 3HDBA 1GE6A 1GE7A 2I47A 3Q2GA 2D1OA 1JJ9A 1UTZA 3HB2P 1GO7P 4JQGA 1PWUA 2XS4A 1BKCA 2OY4A 3F17A 3HYGA 3GBOA 2KRJA 1KBCA 3LK8A 5D2BA 2J83A 5D1UA 1ZXVA 2V4BA 2AYKA 1CQRA 2X3CA 1DTHA 5BOYA 2OXUA 4JPAA 4XCTA 1D8FA 2TCLA 3LMCA 4FU4A 4IJOA 4FXQA 1Y93A 3MA2A 2MLSA 2K2GA 4H2EA 3LQBA 2POJA 3N2VA 2W12A 3F1AA 1A85A 1L6JA 5BOTA 2L0RA 1BIWA 1R55A 4XBHA 2X3BA 4GR3A 1EUBA 3TT4A 5I43A 3WV2A 1R1HA 3LILA 3O2XA 4PKSA 3LGPA 3L0VA 1HFSA 3K7LA 3DL1A 3HDAP 2D1NA 1BUDA 1G9KA 4PKVA 3ZXHA 1JK3A 5B5PA 1O0TA 1YP1A 1C7KA 1JIWP 4L63A 1I1IP 1JH1A 3UVCA 1SMPA 3KMEA 3LJTA 2DW1A 2RJPA 3F19A 3TVCA 1FLSA 5I12A 4ILWD 3EDHA 3G42A 2CLTA 3TS4A 830CA 3F18A 4H82A 1ZP5A 3AYKA 1SLMA 966CA 2E2DA 1IADA 1XFZA 1ZXCA 1HOVA 1C3IA 2WOAA 3KMCA 5CXAA 3L0TA 4DD8A 2OW9A 4JA1A 2K9CA 3CKIA 4DV8A 1Q3AA 5I3MA 1GE5A 2O3EA 1KUHA 1PWWA 1YQYA 3OHLA 5D1TA 4FVLA 4XM8A 1YCMA 3DWBA 4GR8A 1ZVXA 1MMQA 1OMJA 5H8XA 1BUVM 1K7IA 3LQ0A 3DNGA 2MLRA 3B92A 2W14A 1IAAA 1FM1A 1R1JA 3V96B 1ROSA 1JANA 1EB6A 5BPAA 3LE9A 1BKCE 2EROA 3USNA 4WK7A 2FV5A 1OM8A 4AXQA 3HY9A 1BM6A 1HFCA 4IN9A 1HY7A 1ASTA 2RJQA 3P24A 3WV3A 1IAGA 2YB9A 3F16A 1SLNA 1PWQA 3SHIA 5I2ZA 1D7XA 3LIKA 1JAOA 3DPEA 4H49A 1IACA
chains in the Genus database with same CATH superfamily
2FV9A 2MZHA 3KEKA 3HBUP 1OO9A 1UMTA 4A3WA 4HX3A 4AYKA 1XAXA 4CTHA 3ELMA 1K7GA 4PKTA 1J7NA 3TSKA 1CXVA 3B8ZA 1XUCA 3AIGA 1I76A 3DTEA 2X7MA 1K7QA 2SRTA 3KWVC 4FXYP 2A8HA 1UMSA 3I7GA 1ZTQA 1UTTA 1CAQA 3KHIA 3DTIA 4H1QA 1RM8A 3DPFA 2J0TA 1G49A 1BZSA 3OHOA 5JMYA 2N8RA 3B2ZA 1BKCI 1C8TA 4H84A 4R3VA 3RTTA 2JNPA 1XUDA 4EFSA 1MMRA 1RMZA 1GO8P 5CUHA 4L19A 2ERPA 3LUMA 1G05A 2Y6DA 1GXDA 4PKUA 3EDIA 2DDYA 3WV1A 1BQOA 4IUWA 1OM6A 1ND1A 2WO9A 2W15A 1JIZA 1HTDA 2OW2A 1WNIA 2MZIA 2JT5A 3EWJA 4AIGA 4GQLA 2AIGP 3I7IA 4I03A 5L7FA 4J4MA 1AYKA 2OW1A 1USNA 1QJJA 1JAQA 1BQQM 2OXZA 2OY2A 3ZVSA 3EHXA 1G12A 4H3XA 1CGEA 1HV5A 1GKCA 4A7BA 4DF9A 4WZVA 2OVZA 1Y0VA 4ZR5A 1AF0A 1MNCA 2OW0A 1MMPA 3G5CA 3HY7A 1IAEA 3K7NA 1Y8JA 3U1RA 4ON1A 1AKLA 2CKIA 3F15A 5I0LA 1OM7A 1KUFA 1QJIA 4GWMA 3VTGA 1XFUA 1O0QA 2OVXA 4GR0A 1CIZA 1SRPA 1EAKA 1KUIA 1KUKA 3EDGA 4JIJA 1DMTA 1R1IA 3LKAA 3P1VA 2X3AA 3E8RA 1YOUA 2OXWA 1JKYA 3LJGA 3LJZA 1R54A 1BSWA 4G9LA 2OI0A 1SU3A 3DSLA 1H71P 3DTKA 2JSDA 4PKQA 4WF6A 1B8YA 2USNA 1KAPP 1ZS0A 4AUOA 1FBLA 1I73A 1KUGA 5D7WA 3BA0A 3ZUKA 1CK7A 2E3XA 1PWVA 2WO8A 1ATLA 1OS9A 2JIHA 4H30A 2YIGA 5D1SA 1XURA 1A86A 2W0DA 3LIRA 2ERQA 4H76A 3O64A 1PWPA 4WKEA 1TVIA 5I4OA 5L79A 1XFVA 5CZMA 1JAPA 1QIBA 4PKWA 4XM7A 2XS3A 2HU6A 3VI1A 1SATA 1G4KA 4GWNA 1CGFA 3KECA 4GUYA 1QUAA 456CA 1XFXA 5D3CA 5B5OA 3LUNA 2DW0A 4QKZA 2MZEA 1OS2A 2OZRA 4GF1A 1CGLA 1D8MA 3KRYA 3NX7A 2QPJA 2Y6CA 4L6TA 1OZ9A 4Q1LA 2DW2A 1GKDA 1IABA 1QICA 1MMBA 3HBVP 4HMAA 1D5JA 3LEAA 5LABA 1UEAA 4DPEA 4G0DA 2O36A 3RTSA 1S4BP 3EDZA 4PKRA 1XFWA 1XFYA 1QIAA 2DDFA 2W13A 1Z3JA 4I35A 1B3DA 2PJTA 2Z2DA 4XM6A 3AYUA 3N2UA 1XM5A 2JT6A 3EHYA 4JP4A 3KEJA 4WKIA 3Q2HA 3HDBA 1GE6A 1GE7A 2I47A 3Q2GA 2D1OA 1JJ9A 1UTZA 3HB2P 1GO7P 4JQGA 1PWUA 2XS4A 1BKCA 2OY4A 3F17A 3HYGA 3GBOA 2KRJA 1KBCA 3LK8A 5D2BA 2J83A 5D1UA 1ZXVA 2V4BA 2AYKA 1CQRA 2X3CA 1DTHA 5BOYA 2OXUA 4JPAA 4XCTA 1D8FA 2TCLA 3LMCA 4FU4A 4IJOA 4FXQA 1Y93A 3MA2A 2MLSA 2K2GA 4H2EA 3LQBA 2POJA 3N2VA 2W12A 3F1AA 1A85A 1L6JA 5BOTA 2L0RA 1BIWA 1R55A 4XBHA 2X3BA 4GR3A 1EUBA 3TT4A 5I43A 3WV2A 1R1HA 3LILA 3O2XA 4PKSA 3LGPA 3L0VA 1HFSA 3K7LA 3DL1A 3HDAP 2D1NA 1BUDA 1G9KA 4PKVA 3ZXHA 1JK3A 5B5PA 1O0TA 1YP1A 1C7KA 1JIWP 4L63A 1I1IP 1JH1A 3UVCA 1SMPA 3KMEA 3LJTA 2DW1A 2RJPA 3F19A 3TVCA 1FLSA 5I12A 4ILWD 3EDHA 3G42A 2CLTA 3TS4A 830CA 3F18A 4H82A 4L7AA 1ZP5A 3AYKA 1SLMA 966CA 2E2DA 1IADA 1XFZA 1ZXCA 1HOVA 1C3IA 2WOAA 3KMCA 5CXAA 3L0TA 4DD8A 2OW9A 4JA1A 2K9CA 3CKIA 4DV8A 1Q3AA 5I3MA 1GE5A 2O3EA 1KUHA 1PWWA 1YQYA 3OHLA 5D1TA 4FVLA 4XM8A 1YCMA 3DWBA 4GR8A 1ZVXA 1MMQA 1OMJA 5H8XA 1BUVM 1K7IA 3LQ0A 3DNGA 2MLRA 3B92A 2W14A 1IAAA 1FM1A 1R1JA 3V96B 1ROSA 1JANA 1EB6A 5BPAA 3LE9A 1BKCE 2EROA 3USNA 4WK7A 2FV5A 1OM8A 4AXQA 3HY9A 1BM6A 1HFCA 2YUFA 1HY7A 4IN9A 1ASTA 2RJQA 3P24A 3WV3A 1IAGA 2YB9A 3F16A 1SLNA 1PWQA 3SHIA 5I2ZA 1D7XA 3LIKA 1JAOA 3DPEA 4H49A 1IACA
chains in the Genus database with same CATH topology
2FV9A 2MZHA 3KEKA 3HBUP 1OO9A 1UMTA 4A3WA 4HX3A 4AYKA 4CTHA 3ELMA 1K7GA 4PKTA 1J7NA 3TSKA 1CXVA 3B8ZA 1XUCA 3AIGA 1I76A 3DTEA 2X7MA 1K7QA 2SRTA 3KWVC 4FXYP 2A8HA 1UMSA 3I7GA 1ZTQA 1UTTA 1CAQA 3KHIA 3DTIA 4H1QA 1RM8A 3DPFA 2J0TA 1G49A 1BZSA 3OHOA 5JMYA 2N8RA 3B2ZA 1BKCI 1C8TA 4H84A 4R3VA 3RTTA 2JNPA 1XUDA 4EFSA 1MMRA 1RMZA 1GO8P 5CUHA 4L19A 2ERPA 3LUMA 1G05A 2Y6DA 1GXDA 4PKUA 3EDIA 2DDYA 3WV1A 1BQOA 4IUWA 1OM6A 1ND1A 2WO9A 2W15A 1JIZA 1HTDA 2OW2A 1WNIA 2MZIA 2JT5A 3EWJA 4AIGA 4GQLA 2AIGP 3I7IA 4I03A 5L7FA 4J4MA 1AYKA 2OW1A 1USNA 1QJJA 1JAQA 1BQQM 2OXZA 2OY2A 3ZVSA 3EHXA 1G12A 4H3XA 1CGEA 1HV5A 1GKCA 4A7BA 4DF9A 4WZVA 2OVZA 1Y0VA 4ZR5A 1AF0A 1MNCA 2OW0A 1MMPA 3G5CA 3HY7A 1IAEA 3K7NA 1Y8JA 3U1RA 4ON1A 1AKLA 2CKIA 3F15A 5I0LA 1OM7A 1KUFA 1QJIA 4GWMA 3VTGA 1XFUA 1O0QA 2OVXA 4GR0A 1CIZA 1SRPA 1EAKA 1KUIA 1KUKA 3EDGA 4JIJA 1DMTA 1R1IA 3LKAA 3P1VA 2X3AA 3E8RA 1YOUA 2OXWA 1JKYA 3LJGA 3LJZA 1R54A 1BSWA 4G9LA 2OI0A 1SU3A 3DSLA 1H71P 3DTKA 2JSDA 4PKQA 4WF6A 1B8YA 2USNA 1KAPP 1ZS0A 4AUOA 1FBLA 1I73A 1KUGA 5D7WA 3BA0A 3ZUKA 1CK7A 2E3XA 1PWVA 2WO8A 1ATLA 1OS9A 2JIHA 4H30A 2YIGA 5D1SA 1XURA 1A86A 2W0DA 3LIRA 2ERQA 4H76A 3O64A 1PWPA 4WKEA 5I4OA 5L79A 1XFVA 5CZMA 1JAPA 1QIBA 4PKWA 4XM7A 2XS3A 2HU6A 3VI1A 1SATA 1G4KA 4GWNA 1CGFA 3KECA 4GUYA 1QUAA 456CA 1XFXA 5D3CA 5B5OA 3LUNA 2DW0A 4QKZA 2MZEA 1OS2A 2OZRA 4GF1A 1CGLA 1D8MA 3KRYA 3NX7A 2QPJA 2Y6CA 4L6TA 4Q1LA 2DW2A 1GKDA 1IABA 1QICA 1MMBA 3HBVP 4HMAA 1D5JA 3LEAA 5LABA 1UEAA 4DPEA 4G0DA 2O36A 3RTSA 1S4BP 3EDZA 4PKRA 1XFWA 1XFYA 1QIAA 2DDFA 2W13A 1Z3JA 4I35A 1B3DA 2PJTA 2Z2DA 4XM6A 3AYUA 3N2UA 2JT6A 3EHYA 4JP4A 3KEJA 4WKIA 3Q2HA 3HDBA 1GE6A 1GE7A 2I47A 3Q2GA 2D1OA 1JJ9A 1UTZA 3HB2P 1GO7P 4JQGA 1PWUA 2XS4A 1BKCA 2OY4A 3F17A 3HYGA 3GBOA 2KRJA 1KBCA 3LK8A 5D2BA 2J83A 5D1UA 1ZXVA 2V4BA 2AYKA 1CQRA 2X3CA 1DTHA 5BOYA 2OXUA 4JPAA 4XCTA 1D8FA 2TCLA 3LMCA 4FU4A 4IJOA 4FXQA 1Y93A 3MA2A 2MLSA 2K2GA 4H2EA 3LQBA 2POJA 3N2VA 2W12A 3F1AA 1A85A 1L6JA 5BOTA 2L0RA 1BIWA 1R55A 4XBHA 2X3BA 4GR3A 1EUBA 3TT4A 5I43A 3WV2A 1R1HA 3LILA 3O2XA 4PKSA 3LGPA 3L0VA 1HFSA 3K7LA 3DL1A 3HDAP 2D1NA 1BUDA 1G9KA 4PKVA 3ZXHA 1JK3A 5B5PA 1O0TA 1YP1A 1C7KA 1JIWP 4L63A 1I1IP 1JH1A 3UVCA 1SMPA 3KMEA 3LJTA 2DW1A 2RJPA 3F19A 3TVCA 1FLSA 5I12A 4ILWD 3EDHA 3G42A 2CLTA 3TS4A 830CA 3F18A 4H82A 4L7AA 1ZP5A 3AYKA 1SLMA 966CA 2E2DA 1IADA 1XFZA 1ZXCA 1HOVA 1C3IA 2WOAA 3KMCA 5CXAA 3L0TA 4DD8A 2OW9A 4JA1A 2K9CA 3CKIA 4DV8A 1Q3AA 5I3MA 1GE5A 2O3EA 1KUHA 1PWWA 1YQYA 3OHLA 5D1TA 4FVLA 4XM8A 1YCMA 3DWBA 4GR8A 1ZVXA 1MMQA 1OMJA 5H8XA 1BUVM 1K7IA 3LQ0A 3DNGA 2MLRA 3B92A 2W14A 1IAAA 1FM1A 1R1JA 3V96B 1ROSA 1JANA 1EB6A 5BPAA 3LE9A 1BKCE 2EROA 3USNA 4WK7A 2FV5A 1OM8A 4AXQA 3HY9A 1BM6A 1HFCA 2YUFA 1HY7A 4IN9A 1ASTA 2RJQA 3P24A 3WV3A 1IAGA 2YB9A 3F16A 1SLNA 1PWQA 3SHIA 5I2ZA 1D7XA 3LIKA 1JAOA 3DPEA 4H49A 1IACA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FV9 A;  2MZH A;  3KEK A;  3HBU P;  1OO9 A;  1UMT A;  4A3W A;  4HX3 A;  4AYK A;  4CTH A;  3ELM A;  1K7G A;  4PKT A;  1J7N A;  3TSK A;  1CXV A;  3B8Z A;  1XUC A;  3AIG A;  1I76 A;  2X7M A;  1K7Q A;  2SRT A;  3KWV C;  4FXY P;  2A8H A;  1UMS A;  3I7G A;  1ZTQ A;  1UTT A;  1CAQ A;  3KHI A;  4H1Q A;  1RM8 A;  3DPF A;  2J0T A;  1G49 A;  1BZS A;  3OHO A;  5JMY A;  2N8R A;  3B2Z A;  1BKC I;  1C8T A;  4H84 A;  4R3V A;  3RTT A;  2JNP A;  1XUD A;  4EFS A;  1MMR A;  1RMZ A;  1GO8 P;  5CUH A;  4L19 A;  2ERP A;  3LUM A;  1G05 A;  2Y6D A;  1GXD A;  4PKU A;  3EDI A;  2DDY A;  3WV1 A;  1BQO A;  4IUW A;  1OM6 A;  1ND1 A;  2WO9 A;  2W15 A;  1JIZ A;  1HTD A;  2OW2 A;  1WNI A;  2MZI A;  2JT5 A;  3EWJ A;  4AIG A;  4GQL A;  2AIG P;  3I7I A;  4I03 A;  5L7F A;  4J4M A;  1AYK A;  2OW1 A;  1USN A;  1QJJ A;  1JAQ A;  1BQQ M;  2OXZ A;  2OY2 A;  3ZVS A;  3EHX A;  1G12 A;  4H3X A;  1CGE A;  1HV5 A;  1GKC A;  4A7B A;  4DF9 A;  4WZV A;  2OVZ A;  1Y0V A;  4ZR5 A;  1AF0 A;  1MNC A;  2OW0 A;  1MMP A;  3G5C A;  3HY7 A;  1IAE A;  3K7N A;  1Y8J A;  3U1R A;  4ON1 A;  1AKL A;  2CKI A;  3F15 A;  5I0L A;  1OM7 A;  1KUF A;  1QJI A;  4GWM A;  3VTG A;  1XFU A;  1O0Q A;  2OVX A;  4GR0 A;  1CIZ A;  1SRP A;  1EAK A;  1KUI A;  1KUK A;  3EDG A;  4JIJ A;  1DMT A;  1R1I A;  3LKA A;  3P1V A;  2X3A A;  3E8R A;  1YOU A;  2OXW A;  1JKY A;  3LJG A;  3LJZ A;  1R54 A;  1BSW A;  4G9L A;  2OI0 A;  1SU3 A;  3DSL A;  1H71 P;  2JSD A;  4PKQ A;  4WF6 A;  1B8Y A;  2USN A;  1KAP P;  1ZS0 A;  4AUO A;  1FBL A;  1I73 A;  1KUG A;  5D7W A;  3BA0 A;  3ZUK A;  1CK7 A;  2E3X A;  1PWV A;  2WO8 A;  1ATL A;  1OS9 A;  2JIH A;  4H30 A;  2YIG A;  5D1S A;  1XUR A;  1A86 A;  2W0D A;  3LIR A;  2ERQ A;  4H76 A;  3O64 A;  1PWP A;  4WKE A;  5I4O A;  5L79 A;  1XFV A;  5CZM A;  1JAP A;  1QIB A;  4PKW A;  4XM7 A;  2XS3 A;  2HU6 A;  3VI1 A;  1SAT A;  1G4K A;  4GWN A;  1CGF A;  3KEC A;  4GUY A;  1QUA A;  456C A;  1XFX A;  5D3C A;  5B5O A;  3LUN A;  2DW0 A;  4QKZ A;  2MZE A;  1OS2 A;  2OZR A;  4GF1 A;  1CGL A;  1D8M A;  3KRY A;  3NX7 A;  2QPJ A;  2Y6C A;  4L6T A;  4Q1L A;  2DW2 A;  1GKD A;  1IAB A;  1QIC A;  1MMB A;  3HBV P;  4HMA A;  1D5J A;  3LEA A;  5LAB A;  1UEA A;  4DPE A;  4G0D A;  2O36 A;  3RTS A;  1S4B P;  3EDZ A;  4PKR A;  1XFW A;  1XFY A;  1QIA A;  2DDF A;  2W13 A;  1Z3J A;  4I35 A;  1B3D A;  2PJT A;  2Z2D A;  4XM6 A;  3AYU A;  3N2U A;  2JT6 A;  3EHY A;  4JP4 A;  3KEJ A;  4WKI A;  3Q2H A;  3HDB A;  1GE6 A;  1GE7 A;  2I47 A;  3Q2G A;  2D1O A;  1JJ9 A;  1UTZ A;  3HB2 P;  1GO7 P;  4JQG A;  1PWU A;  2XS4 A;  1BKC A;  2OY4 A;  3F17 A;  3HYG A;  3GBO A;  2KRJ A;  1KBC A;  3LK8 A;  5D2B A;  2J83 A;  5D1U A;  1ZXV A;  2V4B A;  2AYK A;  1CQR A;  2X3C A;  1DTH A;  5BOY A;  2OXU A;  4JPA A;  4XCT A;  1D8F A;  2TCL A;  3LMC A;  4FU4 A;  4IJO A;  4FXQ A;  1Y93 A;  3MA2 A;  2MLS A;  2K2G A;  4H2E A;  3LQB A;  2POJ A;  3N2V A;  2W12 A;  3F1A A;  1A85 A;  1L6J A;  5BOT A;  2L0R A;  1BIW A;  1R55 A;  4XBH A;  2X3B A;  4GR3 A;  1EUB A;  3TT4 A;  5I43 A;  3WV2 A;  1R1H A;  3LIL A;  3O2X A;  4PKS A;  3LGP A;  3L0V A;  1HFS A;  3K7L A;  3DL1 A;  3HDA P;  2D1N A;  1BUD A;  1G9K A;  4PKV A;  3ZXH A;  1JK3 A;  5B5P A;  1O0T A;  1YP1 A;  1C7K A;  1JIW P;  4L63 A;  1I1I P;  1JH1 A;  3UVC A;  1SMP A;  3KME A;  3LJT A;  2DW1 A;  2RJP A;  3F19 A;  3TVC A;  1FLS A;  5I12 A;  4ILW D;  3EDH A;  3G42 A;  2CLT A;  3TS4 A;  830C A;  3F18 A;  4H82 A;  1ZP5 A;  3AYK A;  1SLM A;  966C A;  2E2D A;  1IAD A;  1XFZ A;  1ZXC A;  1HOV A;  1C3I A;  2WOA A;  3KMC A;  5CXA A;  3L0T A;  4DD8 A;  2OW9 A;  4JA1 A;  2K9C A;  3CKI A;  4DV8 A;  1Q3A A;  5I3M A;  1GE5 A;  2O3E A;  1KUH A;  1PWW A;  1YQY A;  3OHL A;  5D1T A;  4FVL A;  4XM8 A;  1YCM A;  3DWB A;  4GR8 A;  1ZVX A;  1MMQ A;  1OMJ A;  5H8X A;  1BUV M;  1K7I A;  3LQ0 A;  3DNG A;  2MLR A;  3B92 A;  2W14 A;  1IAA A;  1FM1 A;  1R1J A;  3V96 B;  1ROS A;  1JAN A;  1EB6 A;  5BPA A;  3LE9 A;  1BKC E;  2ERO A;  3USN A;  4WK7 A;  2FV5 A;  1OM8 A;  4AXQ A;  3HY9 A;  1BM6 A;  1HFC A;  4IN9 A;  1HY7 A;  1AST A;  2RJQ A;  3P24 A;  3WV3 A;  1IAG A;  2YB9 A;  3F16 A;  1SLN A;  1PWQ A;  3SHI A;  5I2Z A;  1D7X A;  3LIK A;  1JAO A;  3DPE A;  4H49 A;  1IAC A; 
#chains in the Genus database with same CATH topology
 2FV9 A;  2MZH A;  3KEK A;  3HBU P;  1OO9 A;  1UMT A;  4A3W A;  4HX3 A;  4AYK A;  1XAX A;  4CTH A;  3ELM A;  1K7G A;  4PKT A;  1J7N A;  3TSK A;  1CXV A;  3B8Z A;  1XUC A;  3AIG A;  1I76 A;  3DTE A;  2X7M A;  1K7Q A;  2SRT A;  3KWV C;  4FXY P;  2A8H A;  1UMS A;  3I7G A;  1ZTQ A;  1UTT A;  1CAQ A;  3KHI A;  3DTI A;  4H1Q A;  1RM8 A;  3DPF A;  2J0T A;  1G49 A;  1BZS A;  3OHO A;  5JMY A;  2N8R A;  3B2Z A;  1BKC I;  1C8T A;  4H84 A;  4R3V A;  3RTT A;  2JNP A;  1XUD A;  4EFS A;  1MMR A;  1RMZ A;  1GO8 P;  5CUH A;  4L19 A;  2ERP A;  3LUM A;  1G05 A;  2Y6D A;  1GXD A;  4PKU A;  3EDI A;  2DDY A;  3WV1 A;  1BQO A;  4IUW A;  1OM6 A;  1ND1 A;  2WO9 A;  2W15 A;  1JIZ A;  1HTD A;  2OW2 A;  1WNI A;  2MZI A;  2JT5 A;  3EWJ A;  4AIG A;  4GQL A;  2AIG P;  3I7I A;  4I03 A;  5L7F A;  4J4M A;  1AYK A;  2OW1 A;  1USN A;  1QJJ A;  1JAQ A;  1BQQ M;  2OXZ A;  2OY2 A;  3ZVS A;  3EHX A;  1G12 A;  4H3X A;  1CGE A;  1HV5 A;  1GKC A;  4A7B A;  4DF9 A;  4WZV A;  2OVZ A;  1Y0V A;  4ZR5 A;  1AF0 A;  1MNC A;  2OW0 A;  1MMP A;  3G5C A;  3HY7 A;  1IAE A;  3K7N A;  1Y8J A;  3U1R A;  4ON1 A;  1AKL A;  2CKI A;  3F15 A;  5I0L A;  1OM7 A;  1KUF A;  1QJI A;  4GWM A;  3VTG A;  1XFU A;  1O0Q A;  2OVX A;  4GR0 A;  1CIZ A;  1SRP A;  1EAK A;  1KUI A;  1KUK A;  3EDG A;  4JIJ A;  1DMT A;  1R1I A;  3LKA A;  3P1V A;  2X3A A;  3E8R A;  1YOU A;  2OXW A;  1JKY A;  3LJG A;  3LJZ A;  1R54 A;  1BSW A;  4G9L A;  2OI0 A;  1SU3 A;  3DSL A;  1H71 P;  3DTK A;  2JSD A;  4PKQ A;  4WF6 A;  1B8Y A;  2USN A;  1KAP P;  1ZS0 A;  4AUO A;  1FBL A;  1I73 A;  1KUG A;  5D7W A;  3BA0 A;  3ZUK A;  1CK7 A;  2E3X A;  1PWV A;  2WO8 A;  1ATL A;  1OS9 A;  2JIH A;  4H30 A;  2YIG A;  5D1S A;  1XUR A;  1A86 A;  2W0D A;  3LIR A;  2ERQ A;  4H76 A;  3O64 A;  1PWP A;  4WKE A;  1TVI A;  5I4O A;  5L79 A;  1XFV A;  5CZM A;  1JAP A;  1QIB A;  4PKW A;  4XM7 A;  2XS3 A;  2HU6 A;  3VI1 A;  1SAT A;  1G4K A;  4GWN A;  1CGF A;  3KEC A;  4GUY A;  1QUA A;  456C A;  1XFX A;  5D3C A;  5B5O A;  3LUN A;  2DW0 A;  4QKZ A;  2MZE A;  1OS2 A;  2OZR A;  4GF1 A;  1CGL A;  1D8M A;  3KRY A;  3NX7 A;  2QPJ A;  2Y6C A;  4L6T A;  1OZ9 A;  4Q1L A;  2DW2 A;  1GKD A;  1IAB A;  1QIC A;  1MMB A;  3HBV P;  4HMA A;  1D5J A;  3LEA A;  5LAB A;  1UEA A;  4DPE A;  4G0D A;  2O36 A;  3RTS A;  1S4B P;  3EDZ A;  4PKR A;  1XFW A;  1XFY A;  1QIA A;  2DDF A;  2W13 A;  1Z3J A;  4I35 A;  1B3D A;  2PJT A;  2Z2D A;  4XM6 A;  3AYU A;  3N2U A;  1XM5 A;  2JT6 A;  3EHY A;  4JP4 A;  3KEJ A;  4WKI A;  3Q2H A;  3HDB A;  1GE6 A;  1GE7 A;  2I47 A;  3Q2G A;  2D1O A;  1JJ9 A;  1UTZ A;  3HB2 P;  1GO7 P;  4JQG A;  1PWU A;  2XS4 A;  1BKC A;  2OY4 A;  3F17 A;  3HYG A;  3GBO A;  2KRJ A;  1KBC A;  3LK8 A;  5D2B A;  2J83 A;  5D1U A;  1ZXV A;  2V4B A;  2AYK A;  1CQR A;  2X3C A;  1DTH A;  5BOY A;  2OXU A;  4JPA A;  4XCT A;  1D8F A;  2TCL A;  3LMC A;  4FU4 A;  4IJO A;  4FXQ A;  1Y93 A;  3MA2 A;  2MLS A;  2K2G A;  4H2E A;  3LQB A;  2POJ A;  3N2V A;  2W12 A;  3F1A A;  1A85 A;  1L6J A;  5BOT A;  2L0R A;  1BIW A;  1R55 A;  4XBH A;  2X3B A;  4GR3 A;  1EUB A;  3TT4 A;  5I43 A;  3WV2 A;  1R1H A;  3LIL A;  3O2X A;  4PKS A;  3LGP A;  3L0V A;  1HFS A;  3K7L A;  3DL1 A;  3HDA P;  2D1N A;  1BUD A;  1G9K A;  4PKV A;  3ZXH A;  1JK3 A;  5B5P A;  1O0T A;  1YP1 A;  1C7K A;  1JIW P;  4L63 A;  1I1I P;  1JH1 A;  3UVC A;  1SMP A;  3KME A;  3LJT A;  2DW1 A;  2RJP A;  3F19 A;  3TVC A;  1FLS A;  5I12 A;  4ILW D;  3EDH A;  3G42 A;  2CLT A;  3TS4 A;  830C A;  3F18 A;  4H82 A;  4L7A A;  1ZP5 A;  3AYK A;  1SLM A;  966C A;  2E2D A;  1IAD A;  1XFZ A;  1ZXC A;  1HOV A;  1C3I A;  2WOA A;  3KMC A;  5CXA A;  3L0T A;  4DD8 A;  2OW9 A;  4JA1 A;  2K9C A;  3CKI A;  4DV8 A;  1Q3A A;  5I3M A;  1GE5 A;  2O3E A;  1KUH A;  1PWW A;  1YQY A;  3OHL A;  5D1T A;  4FVL A;  4XM8 A;  1YCM A;  3DWB A;  4GR8 A;  1ZVX A;  1MMQ A;  1OMJ A;  5H8X A;  1BUV M;  1K7I A;  3LQ0 A;  3DNG A;  2MLR A;  3B92 A;  2W14 A;  1IAA A;  1FM1 A;  1R1J A;  3V96 B;  1ROS A;  1JAN A;  1EB6 A;  5BPA A;  3LE9 A;  1BKC E;  2ERO A;  3USN A;  4WK7 A;  2FV5 A;  1OM8 A;  4AXQ A;  3HY9 A;  1BM6 A;  1HFC A;  2YUF A;  1HY7 A;  4IN9 A;  1AST A;  2RJQ A;  3P24 A;  3WV3 A;  1IAG A;  2YB9 A;  3F16 A;  1SLN A;  1PWQ A;  3SHI A;  5I2Z A;  1D7X A;  3LIK A;  1JAO A;  3DPE A;  4H49 A;  1IAC A; 
#chains in the Genus database with same CATH homology
 2FV9 A;  2MZH A;  3KEK A;  3HBU P;  1OO9 A;  1UMT A;  4A3W A;  4HX3 A;  4AYK A;  4CTH A;  3ELM A;  1K7G A;  4PKT A;  1J7N A;  3TSK A;  1CXV A;  3B8Z A;  1XUC A;  3AIG A;  1I76 A;  3DTE A;  2X7M A;  1K7Q A;  2SRT A;  3KWV C;  4FXY P;  2A8H A;  1UMS A;  3I7G A;  1ZTQ A;  1UTT A;  1CAQ A;  3KHI A;  3DTI A;  4H1Q A;  1RM8 A;  3DPF A;  2J0T A;  1G49 A;  1BZS A;  3OHO A;  5JMY A;  2N8R A;  3B2Z A;  1BKC I;  1C8T A;  4H84 A;  4R3V A;  3RTT A;  2JNP A;  1XUD A;  4EFS A;  1MMR A;  1RMZ A;  1GO8 P;  5CUH A;  4L19 A;  2ERP A;  3LUM A;  1G05 A;  2Y6D A;  1GXD A;  4PKU A;  3EDI A;  2DDY A;  3WV1 A;  1BQO A;  4IUW A;  1OM6 A;  1ND1 A;  2WO9 A;  2W15 A;  1JIZ A;  1HTD A;  2OW2 A;  1WNI A;  2MZI A;  2JT5 A;  3EWJ A;  4AIG A;  4GQL A;  2AIG P;  3I7I A;  4I03 A;  5L7F A;  4J4M A;  1AYK A;  2OW1 A;  1USN A;  1QJJ A;  1JAQ A;  1BQQ M;  2OXZ A;  2OY2 A;  3ZVS A;  3EHX A;  1G12 A;  4H3X A;  1CGE A;  1HV5 A;  1GKC A;  4A7B A;  4DF9 A;  4WZV A;  2OVZ A;  1Y0V A;  4ZR5 A;  1AF0 A;  1MNC A;  2OW0 A;  1MMP A;  3G5C A;  3HY7 A;  1IAE A;  3K7N A;  1Y8J A;  3U1R A;  4ON1 A;  1AKL A;  2CKI A;  3F15 A;  5I0L A;  1OM7 A;  1KUF A;  1QJI A;  4GWM A;  3VTG A;  1XFU A;  1O0Q A;  2OVX A;  4GR0 A;  1CIZ A;  1SRP A;  1EAK A;  1KUI A;  1KUK A;  3EDG A;  4JIJ A;  1DMT A;  1R1I A;  3LKA A;  3P1V A;  2X3A A;  3E8R A;  1YOU A;  2OXW A;  1JKY A;  3LJG A;  3LJZ A;  1R54 A;  1BSW A;  4G9L A;  2OI0 A;  1SU3 A;  3DSL A;  1H71 P;  3DTK A;  2JSD A;  4PKQ A;  4WF6 A;  1B8Y A;  2USN A;  1KAP P;  1ZS0 A;  4AUO A;  1FBL A;  1I73 A;  1KUG A;  5D7W A;  3BA0 A;  3ZUK A;  1CK7 A;  2E3X A;  1PWV A;  2WO8 A;  1ATL A;  1OS9 A;  2JIH A;  4H30 A;  2YIG A;  5D1S A;  1XUR A;  1A86 A;  2W0D A;  3LIR A;  2ERQ A;  4H76 A;  3O64 A;  1PWP A;  4WKE A;  5I4O A;  5L79 A;  1XFV A;  5CZM A;  1JAP A;  1QIB A;  4PKW A;  4XM7 A;  2XS3 A;  2HU6 A;  3VI1 A;  1SAT A;  1G4K A;  4GWN A;  1CGF A;  3KEC A;  4GUY A;  1QUA A;  456C A;  1XFX A;  5D3C A;  5B5O A;  3LUN A;  2DW0 A;  4QKZ A;  2MZE A;  1OS2 A;  2OZR A;  4GF1 A;  1CGL A;  1D8M A;  3KRY A;  3NX7 A;  2QPJ A;  2Y6C A;  4L6T A;  4Q1L A;  2DW2 A;  1GKD A;  1IAB A;  1QIC A;  1MMB A;  3HBV P;  4HMA A;  1D5J A;  3LEA A;  5LAB A;  1UEA A;  4DPE A;  4G0D A;  2O36 A;  3RTS A;  1S4B P;  3EDZ A;  4PKR A;  1XFW A;  1XFY A;  1QIA A;  2DDF A;  2W13 A;  1Z3J A;  4I35 A;  1B3D A;  2PJT A;  2Z2D A;  4XM6 A;  3AYU A;  3N2U A;  2JT6 A;  3EHY A;  4JP4 A;  3KEJ A;  4WKI A;  3Q2H A;  3HDB A;  1GE6 A;  1GE7 A;  2I47 A;  3Q2G A;  2D1O A;  1JJ9 A;  1UTZ A;  3HB2 P;  1GO7 P;  4JQG A;  1PWU A;  2XS4 A;  1BKC A;  2OY4 A;  3F17 A;  3HYG A;  3GBO A;  2KRJ A;  1KBC A;  3LK8 A;  5D2B A;  2J83 A;  5D1U A;  1ZXV A;  2V4B A;  2AYK A;  1CQR A;  2X3C A;  1DTH A;  5BOY A;  2OXU A;  4JPA A;  4XCT A;  1D8F A;  2TCL A;  3LMC A;  4FU4 A;  4IJO A;  4FXQ A;  1Y93 A;  3MA2 A;  2MLS A;  2K2G A;  4H2E A;  3LQB A;  2POJ A;  3N2V A;  2W12 A;  3F1A A;  1A85 A;  1L6J A;  5BOT A;  2L0R A;  1BIW A;  1R55 A;  4XBH A;  2X3B A;  4GR3 A;  1EUB A;  3TT4 A;  5I43 A;  3WV2 A;  1R1H A;  3LIL A;  3O2X A;  4PKS A;  3LGP A;  3L0V A;  1HFS A;  3K7L A;  3DL1 A;  3HDA P;  2D1N A;  1BUD A;  1G9K A;  4PKV A;  3ZXH A;  1JK3 A;  5B5P A;  1O0T A;  1YP1 A;  1C7K A;  1JIW P;  4L63 A;  1I1I P;  1JH1 A;  3UVC A;  1SMP A;  3KME A;  3LJT A;  2DW1 A;  2RJP A;  3F19 A;  3TVC A;  1FLS A;  5I12 A;  4ILW D;  3EDH A;  3G42 A;  2CLT A;  3TS4 A;  830C A;  3F18 A;  4H82 A;  4L7A A;  1ZP5 A;  3AYK A;  1SLM A;  966C A;  2E2D A;  1IAD A;  1XFZ A;  1ZXC A;  1HOV A;  1C3I A;  2WOA A;  3KMC A;  5CXA A;  3L0T A;  4DD8 A;  2OW9 A;  4JA1 A;  2K9C A;  3CKI A;  4DV8 A;  1Q3A A;  5I3M A;  1GE5 A;  2O3E A;  1KUH A;  1PWW A;  1YQY A;  3OHL A;  5D1T A;  4FVL A;  4XM8 A;  1YCM A;  3DWB A;  4GR8 A;  1ZVX A;  1MMQ A;  1OMJ A;  5H8X A;  1BUV M;  1K7I A;  3LQ0 A;  3DNG A;  2MLR A;  3B92 A;  2W14 A;  1IAA A;  1FM1 A;  1R1J A;  3V96 B;  1ROS A;  1JAN A;  1EB6 A;  5BPA A;  3LE9 A;  1BKC E;  2ERO A;  3USN A;  4WK7 A;  2FV5 A;  1OM8 A;  4AXQ A;  3HY9 A;  1BM6 A;  1HFC A;  2YUF A;  1HY7 A;  4IN9 A;  1AST A;  2RJQ A;  3P24 A;  3WV3 A;  1IAG A;  2YB9 A;  3F16 A;  1SLN A;  1PWQ A;  3SHI A;  5I2Z A;  1D7X A;  3LIK A;  1JAO A;  3DPE A;  4H49 A;  1IAC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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