2YB9A

Crystal structure of human neutral endopeptidase complexed with a heteroarylalanine diacid.
Total Genus 270
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
270
sequence length
696
structure length
696
Chain Sequence
GICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase
source organism Homo sapiens
publication title Synthesis and Evaluation of Heteroarylalanine Diacids as Potent and Selective Neutral Endopeptidase Inhibitors.
pubmed doi rcsb
molecule keywords NEPRILYSIN
total genus 270
structure length 696
sequence length 696
ec nomenclature ec 3.4.24.11: Neprilysin.
pdb deposition date 2011-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01431 Peptidase_M13 Peptidase family M13
A PF05649 Peptidase_M13_N Peptidase family M13
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1380.10 Mainly Alpha Orthogonal Bundle Neutral endopeptidase; domain 2 Neutral endopeptidase , domain2 2yb9A02
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 2yb9A01
1ZXVA 1CIZA 5B5OA 1KUIA 4AIGA 3LIKA 3LKAA 3LJGA 1JJ9A 2OXUA 1QJIA 2CKIA 3KECA 2JSDA 4JQGA 1JKYA 1IACA 1ROSA 4ON1A 4DV8A 4IUWA 1PWWA 3HY7A 3LK8A 3K7LA 3P1VA 4WK7A 1YQYA 1SLNA 2OVZA 5H8XA 1EAKA 1SU3A 1A85A 1CGLA 1IAGA 2L0RA 1BKCI 3KMCA 5L79A 1DMTA 3GBOA 1QJJA 1OM6A 3UVCA 5D1TA 2X3AA 1O0TA 5I43A 3F1AA 4XCTA 5LABA 5D2BA 1R54A 2OW1A 4JA1A 2A8HA 5I0LA 2PJTA 1R55A 2OXWA 2D1NA 2Y6DA 4HMAA 1G9KA 4QKZA 3TT4A 2QPJA 1CGEA 1BQOA 1C8TA 4WF6A 2WOAA 1BZSA 1MMRA 1ZP5A 1FLSA 1BUVM 2MZHA 1IAEA 4L19A 3I7GA 4A3WA 2EROA 2YB9A 1ZVXA 1K7GA 3SHIA 1K7IA 4PKWA 5JMYA 2WO9A 3K7NA 4GWMA 4GR8A 3HY9A 4WKEA 3WV1A 2OW0A 2OVXA 3DSLA 2J83A 4H3XA 4H2EA 1BIWA 4GR3A 1HFSA 3O2XA 3VTGA 2X3BA 2POJA 2OY4A 3KMEA 1IADA 4GQLA 3P24A 5I12A 1Q3AA 3HBVP 1Y8JA 1UMSA 4PKTA 1PWVA 3B2ZA 3G5CA 5I3MA 4XM7A 5BOYA 2AIGP 3DL1A 1ZTQA 3Q2GA 4H1QA 3LUMA 2MZIA 1I76A 2WO8A 1MMPA 4IJOA 2V4BA 1R1IA 2OZRA 3LGPA 3HYGA 2K9CA 1WNIA 4H84A 3TSKA 1G49A 3KWVC 1PWQA 2USNA 3WV2A 3EDGA 4AXQA 3F19A 3EHYA 1J7NA 4FU4A 1JIZA 3DNGA 1GKDA 1QIAA 1XFZA 3RTSA 1KUKA 4FXQA 3LUNA 3Q2HA 3EDHA 1SRPA 3WV3A 2CLTA 3LEAA 1Y0VA 1HY7A 1AF0A 4PKSA 4CTHA 5I4OA 5CXAA 1AYKA 2W0DA 2Y6CA 4R3VA 2OW2A 4A7BA 1C3IA 1BM6A 4XBHA 3E8RA 1Y93A 2DW0A 1CAQA 3L0VA 2JIHA 4I03A 1S4BP 2MLRA 3F16A 3ELMA 1O0QA 1GO8P 4JP4A 1IAAA 3TVCA 3EWJA 3KEKA 1OS9A 2W12A 1GE5A 4DD8A 2K2GA 3DPFA 3HDBA 3LJZA 4XM6A 1ASTA 3TS4A 1DTHA 4WZVA 3O64A 1JANA 2JT6A 3F18A 1MNCA 1JAOA 2W13A 3BA0A 3VI1A 2J0TA 1OM8A 1ATLA 1D5JA 3HBUP 1KBCA 1EUBA 1KUHA 3KHIA 1RMZA 1HOVA 1GE6A 1G12A 1YOUA 2W15A 2YIGA 2DW2A 4G9LA 2E3XA 5D1UA 1BSWA 4WKIA 2XS3A 1D8FA 1JAPA 2FV5A 5D7WA 1GO7P 1JAQA 4ILWD 1R1JA 1CXVA 1KAPP 1H71P 3L0TA 3LMCA 2KRJA 1XFUA 3G42A 4FXYP 5D1SA 1JK3A 3B8ZA 3LIRA 3AYUA 3LJTA 4H30A 2X7MA 1Z3JA 3N2UA 1SMPA 1UMTA 5BPAA 2MZEA 1ZS0A 2RJQA 4H76A 3RTTA 3N2VA 1CQRA 1OMJA 1JH1A 1UTZA 2Z2DA 1JIWP 1UTTA 3USNA 5D3CA 3DWBA 3U1RA 1G4KA 456CA 4H82A 3LILA 2XS4A 4AYKA 1K7QA 1EB6A 3EHXA 3ZUKA 2OI0A 1C7KA 5CZMA 4ZR5A 1KUGA 1XUCA 4AUOA 1XFWA 1FM1A 2DDYA 1AKLA 1G05A 966CA 4L6TA 3B92A 4PKQA 1B8YA 2JNPA 2OY2A 1QIBA 3DPEA 2JT5A 2X3CA 1BQQM 1YP1A 1R1HA 2DDFA 1GXDA 1MMQA 1I73A 1FBLA 5L7FA 2FV9A 1GE7A 4GR0A 3OHOA 1MMBA 3NX7A 1OS2A 3ZXHA 2TCLA 1HTDA 2OXZA 3AYKA 2D1OA 4PKRA 1UEAA 3KRYA 1QUAA 3LQ0A 4I35A 1ND1A 4H49A 1XFVA 1PWPA 4HX3A 1D7XA 4GWNA 3ZVSA 2OW9A 1KUFA 4GUYA 1OM7A 4PKVA 3LE9A 4JIJA 3F15A 3CKIA 4Q1LA 1CK7A 1SLMA 2O3EA 2RJPA 1XFYA 3KEJA 1YCMA 3F17A 2N8RA 5BOTA 1OO9A 1L6JA 4XM8A 1HV5A 1PWUA 3HDAP 3EDIA 1IABA 3HB2P 1B3DA 2SRTA 1GKCA 1USNA 2HU6A 1BKCA 1HFCA 3EDZA 4DF9A 4FVLA 3V96B 1XURA 4DPEA 1A86A 2AYKA 4L63A 1XUDA 2W14A 1I1IP 2I47A 3AIGA 4IN9A 2E2DA 2MLSA 4G0DA 4JPAA 5B5PA 1QICA 3I7IA 5I2ZA 2DW1A 1SATA 3MA2A 1ZXCA 1XFXA 1CGFA 2ERPA 1BKCE 1D8MA 1RM8A 5CUHA 4EFSA 830CA 3OHLA 2ERQA 1BUDA 4PKUA 3LQBA 2O36A 4J4MA 4GF1A
chains in the Genus database with same CATH superfamily
1ZXVA 1CIZA 5B5OA 1KUIA 4AIGA 3LIKA 3LKAA 3LJGA 1JJ9A 2OXUA 1QJIA 2CKIA 3KECA 1OZ9A 2JSDA 4JQGA 1JKYA 1IACA 1ROSA 4ON1A 4DV8A 4IUWA 1PWWA 3HY7A 3LK8A 3K7LA 3P1VA 4WK7A 1YQYA 3DTKA 1SLNA 2OVZA 5H8XA 1EAKA 1SU3A 1A85A 1CGLA 1IAGA 2L0RA 1BKCI 3KMCA 5L79A 1DMTA 3GBOA 1QJJA 1OM6A 3UVCA 5D1TA 2X3AA 1O0TA 5I43A 3F1AA 4XCTA 5LABA 5D2BA 1R54A 2OW1A 4JA1A 2A8HA 5I0LA 2PJTA 1R55A 2OXWA 2D1NA 2Y6DA 4HMAA 1G9KA 4QKZA 3TT4A 2QPJA 1CGEA 1BQOA 1C8TA 4WF6A 2WOAA 1BZSA 1MMRA 1ZP5A 1FLSA 1BUVM 2MZHA 1IAEA 4L19A 3I7GA 4A3WA 2EROA 2YB9A 1ZVXA 1K7GA 3SHIA 1K7IA 4PKWA 5JMYA 2WO9A 3K7NA 4GWMA 4GR8A 3HY9A 4WKEA 3WV1A 2OW0A 2OVXA 3DSLA 2J83A 4H3XA 4H2EA 1BIWA 4GR3A 1HFSA 3O2XA 3VTGA 2X3BA 2POJA 2OY4A 3KMEA 1IADA 4GQLA 3P24A 5I12A 1Q3AA 3HBVP 3DTIA 1Y8JA 1UMSA 4PKTA 1PWVA 2YUFA 3B2ZA 3G5CA 5I3MA 4XM7A 5BOYA 2AIGP 3DL1A 1ZTQA 3Q2GA 4H1QA 3LUMA 2MZIA 1I76A 2WO8A 1MMPA 4IJOA 2V4BA 1R1IA 2OZRA 3LGPA 3HYGA 2K9CA 1WNIA 4H84A 3TSKA 1G49A 3KWVC 1PWQA 2USNA 3WV2A 3EDGA 4AXQA 3F19A 3EHYA 1J7NA 4FU4A 1JIZA 3DNGA 1GKDA 1QIAA 1XFZA 1XAXA 3RTSA 1KUKA 4FXQA 3LUNA 3Q2HA 3EDHA 1SRPA 3WV3A 2CLTA 3LEAA 1Y0VA 3DTEA 1HY7A 1AF0A 1XM5A 4PKSA 4CTHA 5I4OA 5CXAA 1AYKA 2W0DA 2Y6CA 4R3VA 2OW2A 4A7BA 1C3IA 1BM6A 4XBHA 3E8RA 1Y93A 2DW0A 1CAQA 3L0VA 2JIHA 4I03A 1S4BP 2MLRA 3F16A 3ELMA 1O0QA 1GO8P 4JP4A 1IAAA 3TVCA 3EWJA 3KEKA 1OS9A 2W12A 1GE5A 4DD8A 2K2GA 3DPFA 3HDBA 3LJZA 4XM6A 1ASTA 3TS4A 1DTHA 4WZVA 3O64A 1JANA 2JT6A 3F18A 1MNCA 1JAOA 2W13A 3BA0A 3VI1A 2J0TA 1OM8A 1ATLA 1D5JA 3HBUP 1KBCA 1EUBA 1KUHA 3KHIA 1RMZA 1HOVA 1GE6A 1G12A 1YOUA 2W15A 2YIGA 2DW2A 4G9LA 2E3XA 5D1UA 1BSWA 4WKIA 2XS3A 1D8FA 1JAPA 2FV5A 5D7WA 1GO7P 1JAQA 4ILWD 1R1JA 1CXVA 1KAPP 1H71P 3L0TA 3LMCA 2KRJA 1XFUA 3G42A 4FXYP 5D1SA 1JK3A 3B8ZA 3LIRA 3AYUA 3LJTA 4H30A 2X7MA 1Z3JA 3N2UA 1SMPA 1UMTA 5BPAA 2MZEA 1ZS0A 2RJQA 4H76A 3RTTA 3N2VA 1CQRA 1OMJA 1JH1A 1UTZA 2Z2DA 1JIWP 1UTTA 3USNA 5D3CA 3DWBA 3U1RA 1G4KA 456CA 4H82A 3LILA 2XS4A 4AYKA 1K7QA 1EB6A 4L7AA 3EHXA 3ZUKA 2OI0A 1C7KA 5CZMA 4ZR5A 1KUGA 1XUCA 4AUOA 1XFWA 1FM1A 2DDYA 1AKLA 1G05A 966CA 4L6TA 3B92A 4PKQA 1B8YA 2JNPA 2OY2A 1QIBA 3DPEA 2JT5A 2X3CA 1BQQM 1YP1A 1R1HA 2DDFA 1GXDA 1MMQA 1I73A 1FBLA 5L7FA 2FV9A 1GE7A 4GR0A 3OHOA 1MMBA 3NX7A 1OS2A 3ZXHA 2TCLA 1HTDA 2OXZA 3AYKA 2D1OA 4PKRA 1UEAA 3KRYA 1QUAA 3LQ0A 4I35A 1ND1A 4H49A 1XFVA 1PWPA 4HX3A 1D7XA 4GWNA 3ZVSA 2OW9A 1KUFA 4GUYA 1OM7A 4PKVA 3LE9A 4JIJA 3F15A 3CKIA 4Q1LA 1CK7A 1SLMA 2O3EA 2RJPA 1XFYA 3KEJA 1YCMA 3F17A 2N8RA 5BOTA 1OO9A 1L6JA 4XM8A 1HV5A 1PWUA 3HDAP 3EDIA 1IABA 3HB2P 1B3DA 2SRTA 1GKCA 1USNA 2HU6A 1BKCA 1HFCA 3EDZA 4DF9A 1TVIA 4FVLA 3V96B 1XURA 4DPEA 1A86A 2AYKA 4L63A 1XUDA 2W14A 1I1IP 2I47A 3AIGA 4IN9A 2E2DA 2MLSA 4G0DA 4JPAA 5B5PA 1QICA 3I7IA 5I2ZA 2DW1A 1SATA 3MA2A 1ZXCA 1XFXA 1CGFA 2ERPA 1BKCE 1D8MA 1RM8A 5CUHA 4EFSA 830CA 3OHLA 2ERQA 1BUDA 4PKUA 3LQBA 2O36A 4J4MA 4GF1A
chains in the Genus database with same CATH topology
1ZXVA 1CIZA 5B5OA 1KUIA 4AIGA 3LIKA 3LKAA 3LJGA 1JJ9A 2OXUA 1QJIA 2CKIA 3KECA 2JSDA 4JQGA 1JKYA 1IACA 1ROSA 4ON1A 4DV8A 4IUWA 1PWWA 3HY7A 3LK8A 3K7LA 3P1VA 4WK7A 1YQYA 3DTKA 1SLNA 2OVZA 5H8XA 1EAKA 1SU3A 1A85A 1CGLA 1IAGA 2L0RA 1BKCI 3KMCA 5L79A 1DMTA 3GBOA 1QJJA 1OM6A 3UVCA 5D1TA 2X3AA 1O0TA 5I43A 3F1AA 4XCTA 5LABA 5D2BA 1R54A 2OW1A 4JA1A 2A8HA 5I0LA 2PJTA 1R55A 2OXWA 2D1NA 2Y6DA 4HMAA 1G9KA 4QKZA 3TT4A 2QPJA 1CGEA 1BQOA 1C8TA 4WF6A 2WOAA 1BZSA 1MMRA 1ZP5A 1FLSA 1BUVM 2MZHA 1IAEA 4L19A 3I7GA 4A3WA 2EROA 2YB9A 1ZVXA 1K7GA 3SHIA 1K7IA 4PKWA 5JMYA 2WO9A 3K7NA 4GWMA 4GR8A 3HY9A 4WKEA 3WV1A 2OW0A 2OVXA 3DSLA 2J83A 4H3XA 4H2EA 1BIWA 4GR3A 1HFSA 3O2XA 3VTGA 2X3BA 2POJA 2OY4A 3KMEA 1IADA 4GQLA 3P24A 5I12A 1Q3AA 3HBVP 3DTIA 1Y8JA 1UMSA 4PKTA 1PWVA 2YUFA 3B2ZA 3G5CA 5I3MA 4XM7A 5BOYA 2AIGP 3DL1A 1ZTQA 3Q2GA 4H1QA 3LUMA 2MZIA 1I76A 2WO8A 1MMPA 4IJOA 2V4BA 1R1IA 2OZRA 3LGPA 3HYGA 2K9CA 1WNIA 4H84A 3TSKA 1G49A 3KWVC 1PWQA 2USNA 3WV2A 3EDGA 4AXQA 3F19A 3EHYA 1J7NA 4FU4A 1JIZA 3DNGA 1GKDA 1QIAA 1XFZA 3RTSA 1KUKA 4FXQA 3LUNA 3Q2HA 3EDHA 1SRPA 3WV3A 2CLTA 3LEAA 1Y0VA 3DTEA 1HY7A 1AF0A 4PKSA 4CTHA 5I4OA 5CXAA 1AYKA 2W0DA 2Y6CA 4R3VA 2OW2A 4A7BA 1C3IA 1BM6A 4XBHA 3E8RA 1Y93A 2DW0A 1CAQA 3L0VA 2JIHA 4I03A 1S4BP 2MLRA 3F16A 3ELMA 1O0QA 1GO8P 4JP4A 1IAAA 3TVCA 3EWJA 3KEKA 1OS9A 2W12A 1GE5A 4DD8A 2K2GA 3DPFA 3HDBA 3LJZA 4XM6A 1ASTA 3TS4A 1DTHA 4WZVA 3O64A 1JANA 2JT6A 3F18A 1MNCA 1JAOA 2W13A 3BA0A 3VI1A 2J0TA 1OM8A 1ATLA 1D5JA 3HBUP 1KBCA 1EUBA 1KUHA 3KHIA 1RMZA 1HOVA 1GE6A 1G12A 1YOUA 2W15A 2YIGA 2DW2A 4G9LA 2E3XA 5D1UA 1BSWA 4WKIA 2XS3A 1D8FA 1JAPA 2FV5A 5D7WA 1GO7P 1JAQA 4ILWD 1R1JA 1CXVA 1KAPP 1H71P 3L0TA 3LMCA 2KRJA 1XFUA 3G42A 4FXYP 5D1SA 1JK3A 3B8ZA 3LIRA 3AYUA 3LJTA 4H30A 2X7MA 1Z3JA 3N2UA 1SMPA 1UMTA 5BPAA 2MZEA 1ZS0A 2RJQA 4H76A 3RTTA 3N2VA 1CQRA 1OMJA 1JH1A 1UTZA 2Z2DA 1JIWP 1UTTA 3USNA 5D3CA 3DWBA 3U1RA 1G4KA 456CA 4H82A 3LILA 2XS4A 4AYKA 1K7QA 1EB6A 4L7AA 3EHXA 3ZUKA 2OI0A 1C7KA 5CZMA 4ZR5A 1KUGA 1XUCA 4AUOA 1XFWA 1FM1A 2DDYA 1AKLA 1G05A 966CA 4L6TA 3B92A 4PKQA 1B8YA 2JNPA 2OY2A 1QIBA 3DPEA 2JT5A 2X3CA 1BQQM 1YP1A 1R1HA 2DDFA 1GXDA 1MMQA 1I73A 1FBLA 5L7FA 2FV9A 1GE7A 4GR0A 3OHOA 1MMBA 3NX7A 1OS2A 3ZXHA 2TCLA 1HTDA 2OXZA 3AYKA 2D1OA 4PKRA 1UEAA 3KRYA 1QUAA 3LQ0A 4I35A 1ND1A 4H49A 1XFVA 1PWPA 4HX3A 1D7XA 4GWNA 3ZVSA 2OW9A 1KUFA 4GUYA 1OM7A 4PKVA 3LE9A 4JIJA 3F15A 3CKIA 4Q1LA 1CK7A 1SLMA 2O3EA 2RJPA 1XFYA 3KEJA 1YCMA 3F17A 2N8RA 5BOTA 1OO9A 1L6JA 4XM8A 1HV5A 1PWUA 3HDAP 3EDIA 1IABA 3HB2P 1B3DA 2SRTA 1GKCA 1USNA 2HU6A 1BKCA 1HFCA 3EDZA 4DF9A 4FVLA 3V96B 1XURA 4DPEA 1A86A 2AYKA 4L63A 1XUDA 2W14A 1I1IP 2I47A 3AIGA 4IN9A 2E2DA 2MLSA 4G0DA 4JPAA 5B5PA 1QICA 3I7IA 5I2ZA 2DW1A 1SATA 3MA2A 1ZXCA 1XFXA 1CGFA 2ERPA 1BKCE 1D8MA 1RM8A 5CUHA 4EFSA 830CA 3OHLA 2ERQA 1BUDA 4PKUA 3LQBA 2O36A 4J4MA 4GF1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZXV A;  1CIZ A;  5B5O A;  1KUI A;  4AIG A;  3LIK A;  3LKA A;  3LJG A;  1JJ9 A;  2OXU A;  1QJI A;  2CKI A;  3KEC A;  2JSD A;  4JQG A;  1JKY A;  1IAC A;  1ROS A;  4ON1 A;  4DV8 A;  4IUW A;  1PWW A;  3HY7 A;  3LK8 A;  3K7L A;  3P1V A;  4WK7 A;  1YQY A;  1SLN A;  2OVZ A;  5H8X A;  1EAK A;  1SU3 A;  1A85 A;  1CGL A;  1IAG A;  2L0R A;  1BKC I;  3KMC A;  5L79 A;  1DMT A;  3GBO A;  1QJJ A;  1OM6 A;  3UVC A;  5D1T A;  2X3A A;  1O0T A;  5I43 A;  3F1A A;  4XCT A;  5LAB A;  5D2B A;  1R54 A;  2OW1 A;  4JA1 A;  2A8H A;  5I0L A;  2PJT A;  1R55 A;  2OXW A;  2D1N A;  2Y6D A;  4HMA A;  1G9K A;  4QKZ A;  3TT4 A;  2QPJ A;  1CGE A;  1BQO A;  1C8T A;  4WF6 A;  2WOA A;  1BZS A;  1MMR A;  1ZP5 A;  1FLS A;  1BUV M;  2MZH A;  1IAE A;  4L19 A;  3I7G A;  4A3W A;  2ERO A;  2YB9 A;  1ZVX A;  1K7G A;  3SHI A;  1K7I A;  4PKW A;  5JMY A;  2WO9 A;  3K7N A;  4GWM A;  4GR8 A;  3HY9 A;  4WKE A;  3WV1 A;  2OW0 A;  2OVX A;  3DSL A;  2J83 A;  4H3X A;  4H2E A;  1BIW A;  4GR3 A;  1HFS A;  3O2X A;  3VTG A;  2X3B A;  2POJ A;  2OY4 A;  3KME A;  1IAD A;  4GQL A;  3P24 A;  5I12 A;  1Q3A A;  3HBV P;  1Y8J A;  1UMS A;  4PKT A;  1PWV A;  3B2Z A;  3G5C A;  5I3M A;  4XM7 A;  5BOY A;  2AIG P;  3DL1 A;  1ZTQ A;  3Q2G A;  4H1Q A;  3LUM A;  2MZI A;  1I76 A;  2WO8 A;  1MMP A;  4IJO A;  2V4B A;  1R1I A;  2OZR A;  3LGP A;  3HYG A;  2K9C A;  1WNI A;  4H84 A;  3TSK A;  1G49 A;  3KWV C;  1PWQ A;  2USN A;  3WV2 A;  3EDG A;  4AXQ A;  3F19 A;  3EHY A;  1J7N A;  4FU4 A;  1JIZ A;  3DNG A;  1GKD A;  1QIA A;  1XFZ A;  3RTS A;  1KUK A;  4FXQ A;  3LUN A;  3Q2H A;  3EDH A;  1SRP A;  3WV3 A;  2CLT A;  3LEA A;  1Y0V A;  1HY7 A;  1AF0 A;  4PKS A;  4CTH A;  5I4O A;  5CXA A;  1AYK A;  2W0D A;  2Y6C A;  4R3V A;  2OW2 A;  4A7B A;  1C3I A;  1BM6 A;  4XBH A;  3E8R A;  1Y93 A;  2DW0 A;  1CAQ A;  3L0V A;  2JIH A;  4I03 A;  1S4B P;  2MLR A;  3F16 A;  3ELM A;  1O0Q A;  1GO8 P;  4JP4 A;  1IAA A;  3TVC A;  3EWJ A;  3KEK A;  1OS9 A;  2W12 A;  1GE5 A;  4DD8 A;  2K2G A;  3DPF A;  3HDB A;  3LJZ A;  4XM6 A;  1AST A;  3TS4 A;  1DTH A;  4WZV A;  3O64 A;  1JAN A;  2JT6 A;  3F18 A;  1MNC A;  1JAO A;  2W13 A;  3BA0 A;  3VI1 A;  2J0T A;  1OM8 A;  1ATL A;  1D5J A;  3HBU P;  1KBC A;  1EUB A;  1KUH A;  3KHI A;  1RMZ A;  1HOV A;  1GE6 A;  1G12 A;  1YOU A;  2W15 A;  2YIG A;  2DW2 A;  4G9L A;  2E3X A;  5D1U A;  1BSW A;  4WKI A;  2XS3 A;  1D8F A;  1JAP A;  2FV5 A;  5D7W A;  1GO7 P;  1JAQ A;  4ILW D;  1R1J A;  1CXV A;  1KAP P;  1H71 P;  3L0T A;  3LMC A;  2KRJ A;  1XFU A;  3G42 A;  4FXY P;  5D1S A;  1JK3 A;  3B8Z A;  3LIR A;  3AYU A;  3LJT A;  4H30 A;  2X7M A;  1Z3J A;  3N2U A;  1SMP A;  1UMT A;  5BPA A;  2MZE A;  1ZS0 A;  2RJQ A;  4H76 A;  3RTT A;  3N2V A;  1CQR A;  1OMJ A;  1JH1 A;  1UTZ A;  2Z2D A;  1JIW P;  1UTT A;  3USN A;  5D3C A;  3DWB A;  3U1R A;  1G4K A;  456C A;  4H82 A;  3LIL A;  2XS4 A;  4AYK A;  1K7Q A;  1EB6 A;  3EHX A;  3ZUK A;  2OI0 A;  1C7K A;  5CZM A;  4ZR5 A;  1KUG A;  1XUC A;  4AUO A;  1XFW A;  1FM1 A;  2DDY A;  1AKL A;  1G05 A;  966C A;  4L6T A;  3B92 A;  4PKQ A;  1B8Y A;  2JNP A;  2OY2 A;  1QIB A;  3DPE A;  2JT5 A;  2X3C A;  1BQQ M;  1YP1 A;  1R1H A;  2DDF A;  1GXD A;  1MMQ A;  1I73 A;  1FBL A;  5L7F A;  2FV9 A;  1GE7 A;  4GR0 A;  3OHO A;  1MMB A;  3NX7 A;  1OS2 A;  3ZXH A;  2TCL A;  1HTD A;  2OXZ A;  3AYK A;  2D1O A;  4PKR A;  1UEA A;  3KRY A;  1QUA A;  3LQ0 A;  4I35 A;  1ND1 A;  4H49 A;  1XFV A;  1PWP A;  4HX3 A;  1D7X A;  4GWN A;  3ZVS A;  2OW9 A;  1KUF A;  4GUY A;  1OM7 A;  4PKV A;  3LE9 A;  4JIJ A;  3F15 A;  3CKI A;  4Q1L A;  1CK7 A;  1SLM A;  2O3E A;  2RJP A;  1XFY A;  3KEJ A;  1YCM A;  3F17 A;  2N8R A;  5BOT A;  1OO9 A;  1L6J A;  4XM8 A;  1HV5 A;  1PWU A;  3HDA P;  3EDI A;  1IAB A;  3HB2 P;  1B3D A;  2SRT A;  1GKC A;  1USN A;  2HU6 A;  1BKC A;  1HFC A;  3EDZ A;  4DF9 A;  4FVL A;  3V96 B;  1XUR A;  4DPE A;  1A86 A;  2AYK A;  4L63 A;  1XUD A;  2W14 A;  1I1I P;  2I47 A;  3AIG A;  4IN9 A;  2E2D A;  2MLS A;  4G0D A;  4JPA A;  5B5P A;  1QIC A;  3I7I A;  5I2Z A;  2DW1 A;  1SAT A;  3MA2 A;  1ZXC A;  1XFX A;  1CGF A;  2ERP A;  1BKC E;  1D8M A;  1RM8 A;  5CUH A;  4EFS A;  830C A;  3OHL A;  2ERQ A;  1BUD A;  4PKU A;  3LQB A;  2O36 A;  4J4M A;  4GF1 A; 
#chains in the Genus database with same CATH topology
 1ZXV A;  1CIZ A;  5B5O A;  1KUI A;  4AIG A;  3LIK A;  3LKA A;  3LJG A;  1JJ9 A;  2OXU A;  1QJI A;  2CKI A;  3KEC A;  1OZ9 A;  2JSD A;  4JQG A;  1JKY A;  1IAC A;  1ROS A;  4ON1 A;  4DV8 A;  4IUW A;  1PWW A;  3HY7 A;  3LK8 A;  3K7L A;  3P1V A;  4WK7 A;  1YQY A;  3DTK A;  1SLN A;  2OVZ A;  5H8X A;  1EAK A;  1SU3 A;  1A85 A;  1CGL A;  1IAG A;  2L0R A;  1BKC I;  3KMC A;  5L79 A;  1DMT A;  3GBO A;  1QJJ A;  1OM6 A;  3UVC A;  5D1T A;  2X3A A;  1O0T A;  5I43 A;  3F1A A;  4XCT A;  5LAB A;  5D2B A;  1R54 A;  2OW1 A;  4JA1 A;  2A8H A;  5I0L A;  2PJT A;  1R55 A;  2OXW A;  2D1N A;  2Y6D A;  4HMA A;  1G9K A;  4QKZ A;  3TT4 A;  2QPJ A;  1CGE A;  1BQO A;  1C8T A;  4WF6 A;  2WOA A;  1BZS A;  1MMR A;  1ZP5 A;  1FLS A;  1BUV M;  2MZH A;  1IAE A;  4L19 A;  3I7G A;  4A3W A;  2ERO A;  2YB9 A;  1ZVX A;  1K7G A;  3SHI A;  1K7I A;  4PKW A;  5JMY A;  2WO9 A;  3K7N A;  4GWM A;  4GR8 A;  3HY9 A;  4WKE A;  3WV1 A;  2OW0 A;  2OVX A;  3DSL A;  2J83 A;  4H3X A;  4H2E A;  1BIW A;  4GR3 A;  1HFS A;  3O2X A;  3VTG A;  2X3B A;  2POJ A;  2OY4 A;  3KME A;  1IAD A;  4GQL A;  3P24 A;  5I12 A;  1Q3A A;  3HBV P;  3DTI A;  1Y8J A;  1UMS A;  4PKT A;  1PWV A;  2YUF A;  3B2Z A;  3G5C A;  5I3M A;  4XM7 A;  5BOY A;  2AIG P;  3DL1 A;  1ZTQ A;  3Q2G A;  4H1Q A;  3LUM A;  2MZI A;  1I76 A;  2WO8 A;  1MMP A;  4IJO A;  2V4B A;  1R1I A;  2OZR A;  3LGP A;  3HYG A;  2K9C A;  1WNI A;  4H84 A;  3TSK A;  1G49 A;  3KWV C;  1PWQ A;  2USN A;  3WV2 A;  3EDG A;  4AXQ A;  3F19 A;  3EHY A;  1J7N A;  4FU4 A;  1JIZ A;  3DNG A;  1GKD A;  1QIA A;  1XFZ A;  1XAX A;  3RTS A;  1KUK A;  4FXQ A;  3LUN A;  3Q2H A;  3EDH A;  1SRP A;  3WV3 A;  2CLT A;  3LEA A;  1Y0V A;  3DTE A;  1HY7 A;  1AF0 A;  1XM5 A;  4PKS A;  4CTH A;  5I4O A;  5CXA A;  1AYK A;  2W0D A;  2Y6C A;  4R3V A;  2OW2 A;  4A7B A;  1C3I A;  1BM6 A;  4XBH A;  3E8R A;  1Y93 A;  2DW0 A;  1CAQ A;  3L0V A;  2JIH A;  4I03 A;  1S4B P;  2MLR A;  3F16 A;  3ELM A;  1O0Q A;  1GO8 P;  4JP4 A;  1IAA A;  3TVC A;  3EWJ A;  3KEK A;  1OS9 A;  2W12 A;  1GE5 A;  4DD8 A;  2K2G A;  3DPF A;  3HDB A;  3LJZ A;  4XM6 A;  1AST A;  3TS4 A;  1DTH A;  4WZV A;  3O64 A;  1JAN A;  2JT6 A;  3F18 A;  1MNC A;  1JAO A;  2W13 A;  3BA0 A;  3VI1 A;  2J0T A;  1OM8 A;  1ATL A;  1D5J A;  3HBU P;  1KBC A;  1EUB A;  1KUH A;  3KHI A;  1RMZ A;  1HOV A;  1GE6 A;  1G12 A;  1YOU A;  2W15 A;  2YIG A;  2DW2 A;  4G9L A;  2E3X A;  5D1U A;  1BSW A;  4WKI A;  2XS3 A;  1D8F A;  1JAP A;  2FV5 A;  5D7W A;  1GO7 P;  1JAQ A;  4ILW D;  1R1J A;  1CXV A;  1KAP P;  1H71 P;  3L0T A;  3LMC A;  2KRJ A;  1XFU A;  3G42 A;  4FXY P;  5D1S A;  1JK3 A;  3B8Z A;  3LIR A;  3AYU A;  3LJT A;  4H30 A;  2X7M A;  1Z3J A;  3N2U A;  1SMP A;  1UMT A;  5BPA A;  2MZE A;  1ZS0 A;  2RJQ A;  4H76 A;  3RTT A;  3N2V A;  1CQR A;  1OMJ A;  1JH1 A;  1UTZ A;  2Z2D A;  1JIW P;  1UTT A;  3USN A;  5D3C A;  3DWB A;  3U1R A;  1G4K A;  456C A;  4H82 A;  3LIL A;  2XS4 A;  4AYK A;  1K7Q A;  1EB6 A;  4L7A A;  3EHX A;  3ZUK A;  2OI0 A;  1C7K A;  5CZM A;  4ZR5 A;  1KUG A;  1XUC A;  4AUO A;  1XFW A;  1FM1 A;  2DDY A;  1AKL A;  1G05 A;  966C A;  4L6T A;  3B92 A;  4PKQ A;  1B8Y A;  2JNP A;  2OY2 A;  1QIB A;  3DPE A;  2JT5 A;  2X3C A;  1BQQ M;  1YP1 A;  1R1H A;  2DDF A;  1GXD A;  1MMQ A;  1I73 A;  1FBL A;  5L7F A;  2FV9 A;  1GE7 A;  4GR0 A;  3OHO A;  1MMB A;  3NX7 A;  1OS2 A;  3ZXH A;  2TCL A;  1HTD A;  2OXZ A;  3AYK A;  2D1O A;  4PKR A;  1UEA A;  3KRY A;  1QUA A;  3LQ0 A;  4I35 A;  1ND1 A;  4H49 A;  1XFV A;  1PWP A;  4HX3 A;  1D7X A;  4GWN A;  3ZVS A;  2OW9 A;  1KUF A;  4GUY A;  1OM7 A;  4PKV A;  3LE9 A;  4JIJ A;  3F15 A;  3CKI A;  4Q1L A;  1CK7 A;  1SLM A;  2O3E A;  2RJP A;  1XFY A;  3KEJ A;  1YCM A;  3F17 A;  2N8R A;  5BOT A;  1OO9 A;  1L6J A;  4XM8 A;  1HV5 A;  1PWU A;  3HDA P;  3EDI A;  1IAB A;  3HB2 P;  1B3D A;  2SRT A;  1GKC A;  1USN A;  2HU6 A;  1BKC A;  1HFC A;  3EDZ A;  4DF9 A;  1TVI A;  4FVL A;  3V96 B;  1XUR A;  4DPE A;  1A86 A;  2AYK A;  4L63 A;  1XUD A;  2W14 A;  1I1I P;  2I47 A;  3AIG A;  4IN9 A;  2E2D A;  2MLS A;  4G0D A;  4JPA A;  5B5P A;  1QIC A;  3I7I A;  5I2Z A;  2DW1 A;  1SAT A;  3MA2 A;  1ZXC A;  1XFX A;  1CGF A;  2ERP A;  1BKC E;  1D8M A;  1RM8 A;  5CUH A;  4EFS A;  830C A;  3OHL A;  2ERQ A;  1BUD A;  4PKU A;  3LQB A;  2O36 A;  4J4M A;  4GF1 A; 
#chains in the Genus database with same CATH homology
 1ZXV A;  1CIZ A;  5B5O A;  1KUI A;  4AIG A;  3LIK A;  3LKA A;  3LJG A;  1JJ9 A;  2OXU A;  1QJI A;  2CKI A;  3KEC A;  2JSD A;  4JQG A;  1JKY A;  1IAC A;  1ROS A;  4ON1 A;  4DV8 A;  4IUW A;  1PWW A;  3HY7 A;  3LK8 A;  3K7L A;  3P1V A;  4WK7 A;  1YQY A;  3DTK A;  1SLN A;  2OVZ A;  5H8X A;  1EAK A;  1SU3 A;  1A85 A;  1CGL A;  1IAG A;  2L0R A;  1BKC I;  3KMC A;  5L79 A;  1DMT A;  3GBO A;  1QJJ A;  1OM6 A;  3UVC A;  5D1T A;  2X3A A;  1O0T A;  5I43 A;  3F1A A;  4XCT A;  5LAB A;  5D2B A;  1R54 A;  2OW1 A;  4JA1 A;  2A8H A;  5I0L A;  2PJT A;  1R55 A;  2OXW A;  2D1N A;  2Y6D A;  4HMA A;  1G9K A;  4QKZ A;  3TT4 A;  2QPJ A;  1CGE A;  1BQO A;  1C8T A;  4WF6 A;  2WOA A;  1BZS A;  1MMR A;  1ZP5 A;  1FLS A;  1BUV M;  2MZH A;  1IAE A;  4L19 A;  3I7G A;  4A3W A;  2ERO A;  2YB9 A;  1ZVX A;  1K7G A;  3SHI A;  1K7I A;  4PKW A;  5JMY A;  2WO9 A;  3K7N A;  4GWM A;  4GR8 A;  3HY9 A;  4WKE A;  3WV1 A;  2OW0 A;  2OVX A;  3DSL A;  2J83 A;  4H3X A;  4H2E A;  1BIW A;  4GR3 A;  1HFS A;  3O2X A;  3VTG A;  2X3B A;  2POJ A;  2OY4 A;  3KME A;  1IAD A;  4GQL A;  3P24 A;  5I12 A;  1Q3A A;  3HBV P;  3DTI A;  1Y8J A;  1UMS A;  4PKT A;  1PWV A;  2YUF A;  3B2Z A;  3G5C A;  5I3M A;  4XM7 A;  5BOY A;  2AIG P;  3DL1 A;  1ZTQ A;  3Q2G A;  4H1Q A;  3LUM A;  2MZI A;  1I76 A;  2WO8 A;  1MMP A;  4IJO A;  2V4B A;  1R1I A;  2OZR A;  3LGP A;  3HYG A;  2K9C A;  1WNI A;  4H84 A;  3TSK A;  1G49 A;  3KWV C;  1PWQ A;  2USN A;  3WV2 A;  3EDG A;  4AXQ A;  3F19 A;  3EHY A;  1J7N A;  4FU4 A;  1JIZ A;  3DNG A;  1GKD A;  1QIA A;  1XFZ A;  3RTS A;  1KUK A;  4FXQ A;  3LUN A;  3Q2H A;  3EDH A;  1SRP A;  3WV3 A;  2CLT A;  3LEA A;  1Y0V A;  3DTE A;  1HY7 A;  1AF0 A;  4PKS A;  4CTH A;  5I4O A;  5CXA A;  1AYK A;  2W0D A;  2Y6C A;  4R3V A;  2OW2 A;  4A7B A;  1C3I A;  1BM6 A;  4XBH A;  3E8R A;  1Y93 A;  2DW0 A;  1CAQ A;  3L0V A;  2JIH A;  4I03 A;  1S4B P;  2MLR A;  3F16 A;  3ELM A;  1O0Q A;  1GO8 P;  4JP4 A;  1IAA A;  3TVC A;  3EWJ A;  3KEK A;  1OS9 A;  2W12 A;  1GE5 A;  4DD8 A;  2K2G A;  3DPF A;  3HDB A;  3LJZ A;  4XM6 A;  1AST A;  3TS4 A;  1DTH A;  4WZV A;  3O64 A;  1JAN A;  2JT6 A;  3F18 A;  1MNC A;  1JAO A;  2W13 A;  3BA0 A;  3VI1 A;  2J0T A;  1OM8 A;  1ATL A;  1D5J A;  3HBU P;  1KBC A;  1EUB A;  1KUH A;  3KHI A;  1RMZ A;  1HOV A;  1GE6 A;  1G12 A;  1YOU A;  2W15 A;  2YIG A;  2DW2 A;  4G9L A;  2E3X A;  5D1U A;  1BSW A;  4WKI A;  2XS3 A;  1D8F A;  1JAP A;  2FV5 A;  5D7W A;  1GO7 P;  1JAQ A;  4ILW D;  1R1J A;  1CXV A;  1KAP P;  1H71 P;  3L0T A;  3LMC A;  2KRJ A;  1XFU A;  3G42 A;  4FXY P;  5D1S A;  1JK3 A;  3B8Z A;  3LIR A;  3AYU A;  3LJT A;  4H30 A;  2X7M A;  1Z3J A;  3N2U A;  1SMP A;  1UMT A;  5BPA A;  2MZE A;  1ZS0 A;  2RJQ A;  4H76 A;  3RTT A;  3N2V A;  1CQR A;  1OMJ A;  1JH1 A;  1UTZ A;  2Z2D A;  1JIW P;  1UTT A;  3USN A;  5D3C A;  3DWB A;  3U1R A;  1G4K A;  456C A;  4H82 A;  3LIL A;  2XS4 A;  4AYK A;  1K7Q A;  1EB6 A;  4L7A A;  3EHX A;  3ZUK A;  2OI0 A;  1C7K A;  5CZM A;  4ZR5 A;  1KUG A;  1XUC A;  4AUO A;  1XFW A;  1FM1 A;  2DDY A;  1AKL A;  1G05 A;  966C A;  4L6T A;  3B92 A;  4PKQ A;  1B8Y A;  2JNP A;  2OY2 A;  1QIB A;  3DPE A;  2JT5 A;  2X3C A;  1BQQ M;  1YP1 A;  1R1H A;  2DDF A;  1GXD A;  1MMQ A;  1I73 A;  1FBL A;  5L7F A;  2FV9 A;  1GE7 A;  4GR0 A;  3OHO A;  1MMB A;  3NX7 A;  1OS2 A;  3ZXH A;  2TCL A;  1HTD A;  2OXZ A;  3AYK A;  2D1O A;  4PKR A;  1UEA A;  3KRY A;  1QUA A;  3LQ0 A;  4I35 A;  1ND1 A;  4H49 A;  1XFV A;  1PWP A;  4HX3 A;  1D7X A;  4GWN A;  3ZVS A;  2OW9 A;  1KUF A;  4GUY A;  1OM7 A;  4PKV A;  3LE9 A;  4JIJ A;  3F15 A;  3CKI A;  4Q1L A;  1CK7 A;  1SLM A;  2O3E A;  2RJP A;  1XFY A;  3KEJ A;  1YCM A;  3F17 A;  2N8R A;  5BOT A;  1OO9 A;  1L6J A;  4XM8 A;  1HV5 A;  1PWU A;  3HDA P;  3EDI A;  1IAB A;  3HB2 P;  1B3D A;  2SRT A;  1GKC A;  1USN A;  2HU6 A;  1BKC A;  1HFC A;  3EDZ A;  4DF9 A;  4FVL A;  3V96 B;  1XUR A;  4DPE A;  1A86 A;  2AYK A;  4L63 A;  1XUD A;  2W14 A;  1I1I P;  2I47 A;  3AIG A;  4IN9 A;  2E2D A;  2MLS A;  4G0D A;  4JPA A;  5B5P A;  1QIC A;  3I7I A;  5I2Z A;  2DW1 A;  1SAT A;  3MA2 A;  1ZXC A;  1XFX A;  1CGF A;  2ERP A;  1BKC E;  1D8M A;  1RM8 A;  5CUH A;  4EFS A;  830C A;  3OHL A;  2ERQ A;  1BUD A;  4PKU A;  3LQB A;  2O36 A;  4J4M A;  4GF1 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...