2DDFA

Crystal structure of tace in complex with tapi-2
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
257
structure length
253
Chain Sequence
PDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYGGSPHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Stabilization of the autoproteolysis of TNF-alpha converting enzyme (TACE) results in a novel crystal form suitable for structure-based drug design studies.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords ADAM 17
total genus 82
structure length 253
sequence length 257
chains with identical sequence B
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2006-01-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 2ddfA00
5D3CA 1YOUA 3HB2P 2TCLA 1G12A 2MLSA 3WV2A 3ZVSA 1C7KA 2HU6A 1JIWP 3L0TA 2RJPA 2OW2A 3LQBA 1DMTA 1MMPA 1BUVM 1XFVA 1MNCA 1QJJA 4FU4A 1CAQA 1G05A 2OXWA 4ON1A 3ELMA 1GE7A 3DNGA 1EAKA 1D8MA 1JAPA 4J4MA 2WO9A 1IABA 2X7MA 1SLMA 2YB9A 4IN9A 4WKIA 1XFZA 4I35A 2CKIA 4JP4A 1CXVA 5B5OA 1CGFA 4IJOA 1HTDA 2OXUA 1USNA 1IAAA 2O3EA 1K7GA 1ATLA 1SRPA 830CA 1C3IA 1ZVXA 2O36A 1KUKA 2Y6DA 1MMRA 4AUOA 1QUAA 1G49A 3VTGA 4H30A 1IADA 1D5JA 1I73A 3TS4A 1KUIA 4A3WA 2PJTA 1K7QA 5BPAA 456CA 4L6TA 1BIWA 5LABA 1FBLA 4ZR5A 2AYKA 3TVCA 1FM1A 2JSDA 2KRJA 1OO9A 4I03A 5L79A 5D2BA 1AKLA 1JJ9A 1BUDA 4GQLA 1HFCA 2K2GA 3K7NA 1SU3A 2X3BA 4HMAA 2J0TA 1ZS0A 4H1QA 1J7NA 3F18A 3U1RA 3VI1A 5CZMA 5I3MA 3OHOA 3GBOA 2FV9A 1R55A 3SHIA 4XM6A 1GE5A 4JQGA 1KUHA 3WV3A 4GUYA 3AYUA 2W0DA 1PWVA 3K7LA 3LKAA 3F19A 1I76A 4WF6A 1BM6A 1BSWA 1PWWA 4XM7A 2E2DA 1FLSA 3AIGA 2JIHA 2D1OA 3P1VA 4DF9A 3LMCA 3LJGA 4H2EA 2DDFA 1ASTA 1EB6A 966CA 3Q2GA 2OW0A 4PKVA 4A7BA 1KUFA 2OZRA 3E8RA 1GKDA 1R1JA 5BOYA 1L6JA 1XFYA 1CIZA 1BKCA 2JNPA 2POJA 3KHIA 1AYKA 1CGEA 2W15A 3LILA 3HBVP 3LUMA 3DL1A 1GKCA 1XFXA 5BOTA 1MMBA 4XCTA 1JK3A 3N2UA 4PKUA 4WKEA 1EUBA 3B2ZA 3EDZA 1JAOA 1HFSA 3EHXA 1A85A 4PKQA 3LIRA 2MLRA 1R1IA 4DPEA 1UMTA 1HY7A 4GWNA 3DPEA 5L7FA 2OY2A 1XUDA 2OVZA 3RTTA 2DDYA 1G9KA 1JIZA 4ILWD 3G42A 3B92A 1O0QA 1UTZA 1HV5A 3KEKA 4H84A 5CUHA 3ZXHA 1XFUA 3OHLA 3EDGA 5I43A 2I47A 1UMSA 4FXYP 3F17A 1PWQA 1IAEA 4XM8A 1UEAA 1C8TA 1B8YA 1GO7P 2XS4A 3UVCA 1OM6A 1ROSA 1S4BP 1BQOA 3L0VA 3LE9A 1GXDA 3LJZA 1DTHA 3ZUKA 3RTSA 5H8XA 1WNIA 2FV5A 1UTTA 1JANA 1XFWA 1Q3AA 3DSLA 1GE6A 3LUNA 1SMPA 1GO8P 2W13A 2W14A 1D7XA 1IACA 4GR3A 5I0LA 1IAGA 2MZEA 3KMCA 3TSKA 1XUCA 4QKZA 4GR8A 4PKSA 1BQQM 1RMZA 1OM7A 4Q1LA 5JMYA 1KBCA 1I1IP 2OW1A 3KRYA 1OM8A 1ZTQA 3F1AA 3BA0A 3TT4A 2OY4A 5CXAA 2SRTA 1KUGA 1RM8A 4FVLA 4GF1A 4JA1A 2D1NA 2Y6CA 2OXZA 4AXQA 3HBUP 1A86A 3HDBA 3EWJA 3F15A 2DW2A 1KAPP 1H71P 2J83A 1SLNA 4H49A 1QIAA 1SATA 2XS3A 2AIGP 3KEJA 2X3CA 1YQYA 2N8RA 2YIGA 2K9CA 3CKIA 1G4KA 2V4BA 1CK7A 2MZIA 3LK8A 1QIBA 2CLTA 4IUWA 3B8ZA 2USNA 4G0DA 4H76A 3KMEA 2W12A 1ND1A 4AYKA 3Q2HA 3EDIA 4PKTA 1R1HA 4PKRA 2EROA 1O0TA 1Y8JA 1AF0A 1YCMA 2Z2DA 1B3DA 1QJIA 3I7IA 1JH1A 1BZSA 1XURA 3LJTA 4G9LA 4XBHA 2ERQA 3HY9A 1D8FA 5D7WA 1CQRA 1PWPA 4CTHA 3N2VA 5D1TA 3HDAP 2QPJA 1Y0VA 1HOVA 3EDHA 1YP1A 3HY7A 2OW9A 3DPFA 5D1UA 1QICA 1JKYA 3EHYA 1OMJA 4WK7A 4H82A 2OI0A 2DW1A 1Z3JA 4JIJA 3HYGA 1ZXCA 3V96B 4GR0A 4HX3A 2WO8A 3P24A 5I12A 2OVXA 1BKCI 4L63A 1CGLA 5B5PA 3USNA 3LGPA 2L0RA 1BKCE 2DW0A 1R54A 4R3VA 2ERPA 4L19A 3O64A 3AYKA 4EFSA 4DV8A 3LEAA 1ZXVA 3G5CA 3DWBA 2JT5A 1K7IA 1ZP5A 5I2ZA 4DD8A 3F16A 2E3XA 5D1SA 3WV1A 3MA2A 3O2XA 1JAQA 1OS9A 4GWMA 1PWUA 3KECA 3LIKA 2WOAA 1OS2A 4H3XA 2RJQA 4PKWA 2MZHA 4FXQA 2JT6A 2A8HA 4WZVA 4AIGA 1Y93A 3I7GA 1MMQA 4JPAA 3LQ0A 3KWVC 3NX7A 2X3AA 5I4OA
chains in the Genus database with same CATH superfamily
5D3CA 1YOUA 3HB2P 2TCLA 1G12A 3DTIA 2MLSA 3WV2A 3ZVSA 1C7KA 2HU6A 1JIWP 3L0TA 2RJPA 2OW2A 3LQBA 1DMTA 1MMPA 1BUVM 1XFVA 1MNCA 1QJJA 4FU4A 1CAQA 1G05A 2OXWA 4ON1A 3ELMA 1GE7A 3DNGA 1EAKA 1D8MA 1JAPA 2YUFA 4J4MA 2WO9A 1IABA 2X7MA 1SLMA 2YB9A 4IN9A 4WKIA 1XFZA 4I35A 2CKIA 4JP4A 1CXVA 5B5OA 1CGFA 4IJOA 1HTDA 2OXUA 1USNA 1IAAA 2O3EA 1K7GA 1ATLA 1SRPA 830CA 1C3IA 1ZVXA 2O36A 1KUKA 2Y6DA 1MMRA 4AUOA 1QUAA 1G49A 3VTGA 4H30A 1IADA 1D5JA 1I73A 3TS4A 1KUIA 4A3WA 2PJTA 1K7QA 5BPAA 456CA 4L6TA 1BIWA 5LABA 1FBLA 4ZR5A 2AYKA 3TVCA 1FM1A 2JSDA 2KRJA 1OO9A 4I03A 5L79A 5D2BA 1AKLA 1JJ9A 1BUDA 4GQLA 1HFCA 2K2GA 3K7NA 1SU3A 2X3BA 4HMAA 2J0TA 1ZS0A 4H1QA 1J7NA 3F18A 3U1RA 3VI1A 5CZMA 5I3MA 3OHOA 3GBOA 2FV9A 1R55A 3SHIA 4XM6A 1GE5A 4JQGA 1KUHA 3WV3A 4GUYA 3AYUA 2W0DA 1PWVA 3K7LA 3LKAA 3F19A 1I76A 4WF6A 1BM6A 1BSWA 1PWWA 4XM7A 2E2DA 1FLSA 3AIGA 2JIHA 2D1OA 3P1VA 4DF9A 3LMCA 3LJGA 4H2EA 2DDFA 1ASTA 1EB6A 966CA 3Q2GA 2OW0A 4PKVA 4A7BA 1KUFA 2OZRA 3E8RA 1GKDA 1R1JA 5BOYA 1L6JA 1XFYA 1OZ9A 1CIZA 1BKCA 2JNPA 2POJA 3KHIA 1AYKA 1CGEA 2W15A 3LILA 3HBVP 3LUMA 3DL1A 1GKCA 1XFXA 5BOTA 1MMBA 4XCTA 1JK3A 3N2UA 4PKUA 4WKEA 1EUBA 3B2ZA 3EDZA 1JAOA 1HFSA 3EHXA 1A85A 4PKQA 3LIRA 2MLRA 1R1IA 4DPEA 1UMTA 1HY7A 4GWNA 3DPEA 5L7FA 2OY2A 1XUDA 2OVZA 3RTTA 2DDYA 1G9KA 1JIZA 4ILWD 3G42A 3B92A 1O0QA 1UTZA 1HV5A 3KEKA 4H84A 5CUHA 3ZXHA 1XFUA 3OHLA 3EDGA 5I43A 2I47A 1UMSA 4FXYP 3F17A 1PWQA 1IAEA 4XM8A 1UEAA 1C8TA 1B8YA 1GO7P 2XS4A 3DTKA 3UVCA 1OM6A 1ROSA 1S4BP 1BQOA 3L0VA 3LE9A 1GXDA 3LJZA 1DTHA 3ZUKA 3RTSA 5H8XA 1WNIA 2FV5A 1UTTA 1JANA 1XFWA 1Q3AA 3DSLA 1GE6A 3LUNA 4L7AA 1SMPA 1GO8P 2W13A 2W14A 1D7XA 1IACA 4GR3A 5I0LA 1IAGA 2MZEA 3KMCA 3TSKA 1XUCA 4QKZA 4GR8A 4PKSA 1BQQM 1RMZA 1OM7A 4Q1LA 5JMYA 1KBCA 1I1IP 2OW1A 3KRYA 1OM8A 1ZTQA 3F1AA 3BA0A 3TT4A 2OY4A 5CXAA 2SRTA 1KUGA 1RM8A 4FVLA 4GF1A 4JA1A 2D1NA 2Y6CA 2OXZA 4AXQA 3HBUP 1A86A 3HDBA 3EWJA 3F15A 2DW2A 1KAPP 1TVIA 1H71P 2J83A 1SLNA 4H49A 1QIAA 1SATA 2XS3A 2AIGP 3KEJA 2X3CA 1YQYA 2N8RA 2YIGA 2K9CA 3CKIA 1G4KA 2V4BA 1CK7A 2MZIA 3LK8A 1QIBA 2CLTA 4IUWA 3B8ZA 2USNA 4G0DA 4H76A 3KMEA 2W12A 1ND1A 4AYKA 3Q2HA 3EDIA 4PKTA 1R1HA 4PKRA 2EROA 1O0TA 1Y8JA 1AF0A 1YCMA 2Z2DA 1B3DA 1QJIA 3I7IA 1JH1A 1BZSA 1XURA 3LJTA 4G9LA 4XBHA 2ERQA 3HY9A 1D8FA 5D7WA 1CQRA 1PWPA 4CTHA 3N2VA 5D1TA 3HDAP 2QPJA 1Y0VA 1HOVA 3EDHA 1YP1A 3HY7A 2OW9A 3DPFA 5D1UA 1QICA 1JKYA 3EHYA 1XM5A 1OMJA 4WK7A 4H82A 2OI0A 2DW1A 1Z3JA 4JIJA 3HYGA 1ZXCA 3V96B 4GR0A 4HX3A 2WO8A 3P24A 5I12A 2OVXA 1BKCI 4L63A 1CGLA 5B5PA 3USNA 3LGPA 2L0RA 1BKCE 2DW0A 1R54A 4R3VA 2ERPA 4L19A 3O64A 3AYKA 4EFSA 4DV8A 3LEAA 1ZXVA 3G5CA 3DWBA 2JT5A 1K7IA 1ZP5A 5I2ZA 4DD8A 3F16A 2E3XA 5D1SA 3WV1A 3MA2A 3O2XA 1JAQA 1OS9A 4GWMA 1PWUA 1XAXA 3KECA 3LIKA 2WOAA 1OS2A 4H3XA 2RJQA 4PKWA 2MZHA 4FXQA 2JT6A 2A8HA 4WZVA 4AIGA 1Y93A 3I7GA 1MMQA 4JPAA 3LQ0A 3KWVC 3NX7A 3DTEA 2X3AA 5I4OA
chains in the Genus database with same CATH topology
5D3CA 1YOUA 3HB2P 2TCLA 1G12A 3DTIA 2MLSA 3WV2A 3ZVSA 1C7KA 2HU6A 1JIWP 3L0TA 2RJPA 2OW2A 3LQBA 1DMTA 1MMPA 1BUVM 1XFVA 1MNCA 1QJJA 4FU4A 1CAQA 1G05A 2OXWA 4ON1A 3ELMA 1GE7A 3DNGA 1EAKA 1D8MA 1JAPA 2YUFA 4J4MA 2WO9A 1IABA 2X7MA 1SLMA 2YB9A 4IN9A 4WKIA 1XFZA 4I35A 2CKIA 4JP4A 1CXVA 5B5OA 1CGFA 4IJOA 1HTDA 2OXUA 1USNA 1IAAA 2O3EA 1K7GA 1ATLA 1SRPA 830CA 1C3IA 1ZVXA 2O36A 1KUKA 2Y6DA 1MMRA 4AUOA 1QUAA 1G49A 3VTGA 4H30A 1IADA 1D5JA 1I73A 3TS4A 1KUIA 4A3WA 2PJTA 1K7QA 5BPAA 456CA 4L6TA 1BIWA 5LABA 1FBLA 4ZR5A 2AYKA 3TVCA 1FM1A 2JSDA 2KRJA 1OO9A 4I03A 5L79A 5D2BA 1AKLA 1JJ9A 1BUDA 4GQLA 1HFCA 2K2GA 3K7NA 1SU3A 2X3BA 4HMAA 2J0TA 1ZS0A 4H1QA 1J7NA 3F18A 3U1RA 3VI1A 5CZMA 5I3MA 3OHOA 3GBOA 2FV9A 1R55A 3SHIA 4XM6A 1GE5A 4JQGA 1KUHA 3WV3A 4GUYA 3AYUA 2W0DA 1PWVA 3K7LA 3LKAA 3F19A 1I76A 4WF6A 1BM6A 1BSWA 1PWWA 4XM7A 2E2DA 1FLSA 3AIGA 2JIHA 2D1OA 3P1VA 4DF9A 3LMCA 3LJGA 4H2EA 2DDFA 1ASTA 1EB6A 966CA 3Q2GA 2OW0A 4PKVA 4A7BA 1KUFA 2OZRA 3E8RA 1GKDA 1R1JA 5BOYA 1L6JA 1XFYA 1CIZA 1BKCA 2JNPA 2POJA 3KHIA 1AYKA 1CGEA 2W15A 3LILA 3HBVP 3LUMA 3DL1A 1GKCA 1XFXA 5BOTA 1MMBA 4XCTA 1JK3A 3N2UA 4PKUA 4WKEA 1EUBA 3B2ZA 3EDZA 1JAOA 1HFSA 3EHXA 1A85A 4PKQA 3LIRA 2MLRA 1R1IA 4DPEA 1UMTA 1HY7A 4GWNA 3DPEA 5L7FA 2OY2A 1XUDA 2OVZA 3RTTA 2DDYA 1G9KA 1JIZA 4ILWD 3G42A 3B92A 1O0QA 1UTZA 1HV5A 3KEKA 4H84A 5CUHA 3ZXHA 1XFUA 3OHLA 3EDGA 5I43A 2I47A 1UMSA 4FXYP 3F17A 1PWQA 1IAEA 4XM8A 1UEAA 1C8TA 1B8YA 1GO7P 2XS4A 3DTKA 3UVCA 1OM6A 1ROSA 1S4BP 1BQOA 3L0VA 3LE9A 1GXDA 3LJZA 1DTHA 3ZUKA 3RTSA 5H8XA 1WNIA 2FV5A 1UTTA 1JANA 1XFWA 1Q3AA 3DSLA 1GE6A 3LUNA 4L7AA 1SMPA 1GO8P 2W13A 2W14A 1D7XA 1IACA 4GR3A 5I0LA 1IAGA 2MZEA 3KMCA 3TSKA 1XUCA 4QKZA 4GR8A 4PKSA 1BQQM 1RMZA 1OM7A 4Q1LA 5JMYA 1KBCA 1I1IP 2OW1A 3KRYA 1OM8A 1ZTQA 3F1AA 3BA0A 3TT4A 2OY4A 5CXAA 2SRTA 1KUGA 1RM8A 4FVLA 4GF1A 4JA1A 2D1NA 2Y6CA 2OXZA 4AXQA 3HBUP 1A86A 3HDBA 3EWJA 3F15A 2DW2A 1KAPP 1H71P 2J83A 1SLNA 4H49A 1QIAA 1SATA 2XS3A 2AIGP 3KEJA 2X3CA 1YQYA 2N8RA 2YIGA 2K9CA 3CKIA 1G4KA 2V4BA 1CK7A 2MZIA 3LK8A 1QIBA 2CLTA 4IUWA 3B8ZA 2USNA 4G0DA 4H76A 3KMEA 2W12A 1ND1A 4AYKA 3Q2HA 3EDIA 4PKTA 1R1HA 4PKRA 2EROA 1O0TA 1Y8JA 1AF0A 1YCMA 2Z2DA 1B3DA 1QJIA 3I7IA 1JH1A 1BZSA 1XURA 3LJTA 4G9LA 4XBHA 2ERQA 3HY9A 1D8FA 5D7WA 1CQRA 1PWPA 4CTHA 3N2VA 5D1TA 3HDAP 2QPJA 1Y0VA 1HOVA 3EDHA 1YP1A 3HY7A 2OW9A 3DPFA 5D1UA 1QICA 1JKYA 3EHYA 1OMJA 4WK7A 4H82A 2OI0A 2DW1A 1Z3JA 4JIJA 3HYGA 1ZXCA 3V96B 4GR0A 4HX3A 2WO8A 3P24A 5I12A 2OVXA 1BKCI 4L63A 1CGLA 5B5PA 3USNA 3LGPA 2L0RA 1BKCE 2DW0A 1R54A 4R3VA 2ERPA 4L19A 3O64A 3AYKA 4EFSA 4DV8A 3LEAA 1ZXVA 3G5CA 3DWBA 2JT5A 1K7IA 1ZP5A 5I2ZA 4DD8A 3F16A 2E3XA 5D1SA 3WV1A 3MA2A 3O2XA 1JAQA 1OS9A 4GWMA 1PWUA 3KECA 3LIKA 2WOAA 1OS2A 4H3XA 2RJQA 4PKWA 2MZHA 4FXQA 2JT6A 2A8HA 4WZVA 4AIGA 1Y93A 3I7GA 1MMQA 4JPAA 3LQ0A 3KWVC 3NX7A 3DTEA 2X3AA 5I4OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5D3C A;  1YOU A;  3HB2 P;  2TCL A;  1G12 A;  2MLS A;  3WV2 A;  3ZVS A;  1C7K A;  2HU6 A;  1JIW P;  3L0T A;  2RJP A;  2OW2 A;  3LQB A;  1DMT A;  1MMP A;  1BUV M;  1XFV A;  1MNC A;  1QJJ A;  4FU4 A;  1CAQ A;  1G05 A;  2OXW A;  4ON1 A;  3ELM A;  1GE7 A;  3DNG A;  1EAK A;  1D8M A;  1JAP A;  4J4M A;  2WO9 A;  1IAB A;  2X7M A;  1SLM A;  2YB9 A;  4IN9 A;  4WKI A;  1XFZ A;  4I35 A;  2CKI A;  4JP4 A;  1CXV A;  5B5O A;  1CGF A;  4IJO A;  1HTD A;  2OXU A;  1USN A;  1IAA A;  2O3E A;  1K7G A;  1ATL A;  1SRP A;  830C A;  1C3I A;  1ZVX A;  2O36 A;  1KUK A;  2Y6D A;  1MMR A;  4AUO A;  1QUA A;  1G49 A;  3VTG A;  4H30 A;  1IAD A;  1D5J A;  1I73 A;  3TS4 A;  1KUI A;  4A3W A;  2PJT A;  1K7Q A;  5BPA A;  456C A;  4L6T A;  1BIW A;  5LAB A;  1FBL A;  4ZR5 A;  2AYK A;  3TVC A;  1FM1 A;  2JSD A;  2KRJ A;  1OO9 A;  4I03 A;  5L79 A;  5D2B A;  1AKL A;  1JJ9 A;  1BUD A;  4GQL A;  1HFC A;  2K2G A;  3K7N A;  1SU3 A;  2X3B A;  4HMA A;  2J0T A;  1ZS0 A;  4H1Q A;  1J7N A;  3F18 A;  3U1R A;  3VI1 A;  5CZM A;  5I3M A;  3OHO A;  3GBO A;  2FV9 A;  1R55 A;  3SHI A;  4XM6 A;  1GE5 A;  4JQG A;  1KUH A;  3WV3 A;  4GUY A;  3AYU A;  2W0D A;  1PWV A;  3K7L A;  3LKA A;  3F19 A;  1I76 A;  4WF6 A;  1BM6 A;  1BSW A;  1PWW A;  4XM7 A;  2E2D A;  1FLS A;  3AIG A;  2JIH A;  2D1O A;  3P1V A;  4DF9 A;  3LMC A;  3LJG A;  4H2E A;  2DDF A;  1AST A;  1EB6 A;  966C A;  3Q2G A;  2OW0 A;  4PKV A;  4A7B A;  1KUF A;  2OZR A;  3E8R A;  1GKD A;  1R1J A;  5BOY A;  1L6J A;  1XFY A;  1CIZ A;  1BKC A;  2JNP A;  2POJ A;  3KHI A;  1AYK A;  1CGE A;  2W15 A;  3LIL A;  3HBV P;  3LUM A;  3DL1 A;  1GKC A;  1XFX A;  5BOT A;  1MMB A;  4XCT A;  1JK3 A;  3N2U A;  4PKU A;  4WKE A;  1EUB A;  3B2Z A;  3EDZ A;  1JAO A;  1HFS A;  3EHX A;  1A85 A;  4PKQ A;  3LIR A;  2MLR A;  1R1I A;  4DPE A;  1UMT A;  1HY7 A;  4GWN A;  3DPE A;  5L7F A;  2OY2 A;  1XUD A;  2OVZ A;  3RTT A;  2DDY A;  1G9K A;  1JIZ A;  4ILW D;  3G42 A;  3B92 A;  1O0Q A;  1UTZ A;  1HV5 A;  3KEK A;  4H84 A;  5CUH A;  3ZXH A;  1XFU A;  3OHL A;  3EDG A;  5I43 A;  2I47 A;  1UMS A;  4FXY P;  3F17 A;  1PWQ A;  1IAE A;  4XM8 A;  1UEA A;  1C8T A;  1B8Y A;  1GO7 P;  2XS4 A;  3UVC A;  1OM6 A;  1ROS A;  1S4B P;  1BQO A;  3L0V A;  3LE9 A;  1GXD A;  3LJZ A;  1DTH A;  3ZUK A;  3RTS A;  5H8X A;  1WNI A;  2FV5 A;  1UTT A;  1JAN A;  1XFW A;  1Q3A A;  3DSL A;  1GE6 A;  3LUN A;  1SMP A;  1GO8 P;  2W13 A;  2W14 A;  1D7X A;  1IAC A;  4GR3 A;  5I0L A;  1IAG A;  2MZE A;  3KMC A;  3TSK A;  1XUC A;  4QKZ A;  4GR8 A;  4PKS A;  1BQQ M;  1RMZ A;  1OM7 A;  4Q1L A;  5JMY A;  1KBC A;  1I1I P;  2OW1 A;  3KRY A;  1OM8 A;  1ZTQ A;  3F1A A;  3BA0 A;  3TT4 A;  2OY4 A;  5CXA A;  2SRT A;  1KUG A;  1RM8 A;  4FVL A;  4GF1 A;  4JA1 A;  2D1N A;  2Y6C A;  2OXZ A;  4AXQ A;  3HBU P;  1A86 A;  3HDB A;  3EWJ A;  3F15 A;  2DW2 A;  1KAP P;  1H71 P;  2J83 A;  1SLN A;  4H49 A;  1QIA A;  1SAT A;  2XS3 A;  2AIG P;  3KEJ A;  2X3C A;  1YQY A;  2N8R A;  2YIG A;  2K9C A;  3CKI A;  1G4K A;  2V4B A;  1CK7 A;  2MZI A;  3LK8 A;  1QIB A;  2CLT A;  4IUW A;  3B8Z A;  2USN A;  4G0D A;  4H76 A;  3KME A;  2W12 A;  1ND1 A;  4AYK A;  3Q2H A;  3EDI A;  4PKT A;  1R1H A;  4PKR A;  2ERO A;  1O0T A;  1Y8J A;  1AF0 A;  1YCM A;  2Z2D A;  1B3D A;  1QJI A;  3I7I A;  1JH1 A;  1BZS A;  1XUR A;  3LJT A;  4G9L A;  4XBH A;  2ERQ A;  3HY9 A;  1D8F A;  5D7W A;  1CQR A;  1PWP A;  4CTH A;  3N2V A;  5D1T A;  3HDA P;  2QPJ A;  1Y0V A;  1HOV A;  3EDH A;  1YP1 A;  3HY7 A;  2OW9 A;  3DPF A;  5D1U A;  1QIC A;  1JKY A;  3EHY A;  1OMJ A;  4WK7 A;  4H82 A;  2OI0 A;  2DW1 A;  1Z3J A;  4JIJ A;  3HYG A;  1ZXC A;  3V96 B;  4GR0 A;  4HX3 A;  2WO8 A;  3P24 A;  5I12 A;  2OVX A;  1BKC I;  4L63 A;  1CGL A;  5B5P A;  3USN A;  3LGP A;  2L0R A;  1BKC E;  2DW0 A;  1R54 A;  4R3V A;  2ERP A;  4L19 A;  3O64 A;  3AYK A;  4EFS A;  4DV8 A;  3LEA A;  1ZXV A;  3G5C A;  3DWB A;  2JT5 A;  1K7I A;  1ZP5 A;  5I2Z A;  4DD8 A;  3F16 A;  2E3X A;  5D1S A;  3WV1 A;  3MA2 A;  3O2X A;  1JAQ A;  1OS9 A;  4GWM A;  1PWU A;  3KEC A;  3LIK A;  2WOA A;  1OS2 A;  4H3X A;  2RJQ A;  4PKW A;  2MZH A;  4FXQ A;  2JT6 A;  2A8H A;  4WZV A;  4AIG A;  1Y93 A;  3I7G A;  1MMQ A;  4JPA A;  3LQ0 A;  3KWV C;  3NX7 A;  2X3A A;  5I4O A; 
#chains in the Genus database with same CATH topology
 5D3C A;  1YOU A;  3HB2 P;  2TCL A;  1G12 A;  3DTI A;  2MLS A;  3WV2 A;  3ZVS A;  1C7K A;  2HU6 A;  1JIW P;  3L0T A;  2RJP A;  2OW2 A;  3LQB A;  1DMT A;  1MMP A;  1BUV M;  1XFV A;  1MNC A;  1QJJ A;  4FU4 A;  1CAQ A;  1G05 A;  2OXW A;  4ON1 A;  3ELM A;  1GE7 A;  3DNG A;  1EAK A;  1D8M A;  1JAP A;  2YUF A;  4J4M A;  2WO9 A;  1IAB A;  2X7M A;  1SLM A;  2YB9 A;  4IN9 A;  4WKI A;  1XFZ A;  4I35 A;  2CKI A;  4JP4 A;  1CXV A;  5B5O A;  1CGF A;  4IJO A;  1HTD A;  2OXU A;  1USN A;  1IAA A;  2O3E A;  1K7G A;  1ATL A;  1SRP A;  830C A;  1C3I A;  1ZVX A;  2O36 A;  1KUK A;  2Y6D A;  1MMR A;  4AUO A;  1QUA A;  1G49 A;  3VTG A;  4H30 A;  1IAD A;  1D5J A;  1I73 A;  3TS4 A;  1KUI A;  4A3W A;  2PJT A;  1K7Q A;  5BPA A;  456C A;  4L6T A;  1BIW A;  5LAB A;  1FBL A;  4ZR5 A;  2AYK A;  3TVC A;  1FM1 A;  2JSD A;  2KRJ A;  1OO9 A;  4I03 A;  5L79 A;  5D2B A;  1AKL A;  1JJ9 A;  1BUD A;  4GQL A;  1HFC A;  2K2G A;  3K7N A;  1SU3 A;  2X3B A;  4HMA A;  2J0T A;  1ZS0 A;  4H1Q A;  1J7N A;  3F18 A;  3U1R A;  3VI1 A;  5CZM A;  5I3M A;  3OHO A;  3GBO A;  2FV9 A;  1R55 A;  3SHI A;  4XM6 A;  1GE5 A;  4JQG A;  1KUH A;  3WV3 A;  4GUY A;  3AYU A;  2W0D A;  1PWV A;  3K7L A;  3LKA A;  3F19 A;  1I76 A;  4WF6 A;  1BM6 A;  1BSW A;  1PWW A;  4XM7 A;  2E2D A;  1FLS A;  3AIG A;  2JIH A;  2D1O A;  3P1V A;  4DF9 A;  3LMC A;  3LJG A;  4H2E A;  2DDF A;  1AST A;  1EB6 A;  966C A;  3Q2G A;  2OW0 A;  4PKV A;  4A7B A;  1KUF A;  2OZR A;  3E8R A;  1GKD A;  1R1J A;  5BOY A;  1L6J A;  1XFY A;  1OZ9 A;  1CIZ A;  1BKC A;  2JNP A;  2POJ A;  3KHI A;  1AYK A;  1CGE A;  2W15 A;  3LIL A;  3HBV P;  3LUM A;  3DL1 A;  1GKC A;  1XFX A;  5BOT A;  1MMB A;  4XCT A;  1JK3 A;  3N2U A;  4PKU A;  4WKE A;  1EUB A;  3B2Z A;  3EDZ A;  1JAO A;  1HFS A;  3EHX A;  1A85 A;  4PKQ A;  3LIR A;  2MLR A;  1R1I A;  4DPE A;  1UMT A;  1HY7 A;  4GWN A;  3DPE A;  5L7F A;  2OY2 A;  1XUD A;  2OVZ A;  3RTT A;  2DDY A;  1G9K A;  1JIZ A;  4ILW D;  3G42 A;  3B92 A;  1O0Q A;  1UTZ A;  1HV5 A;  3KEK A;  4H84 A;  5CUH A;  3ZXH A;  1XFU A;  3OHL A;  3EDG A;  5I43 A;  2I47 A;  1UMS A;  4FXY P;  3F17 A;  1PWQ A;  1IAE A;  4XM8 A;  1UEA A;  1C8T A;  1B8Y A;  1GO7 P;  2XS4 A;  3DTK A;  3UVC A;  1OM6 A;  1ROS A;  1S4B P;  1BQO A;  3L0V A;  3LE9 A;  1GXD A;  3LJZ A;  1DTH A;  3ZUK A;  3RTS A;  5H8X A;  1WNI A;  2FV5 A;  1UTT A;  1JAN A;  1XFW A;  1Q3A A;  3DSL A;  1GE6 A;  3LUN A;  4L7A A;  1SMP A;  1GO8 P;  2W13 A;  2W14 A;  1D7X A;  1IAC A;  4GR3 A;  5I0L A;  1IAG A;  2MZE A;  3KMC A;  3TSK A;  1XUC A;  4QKZ A;  4GR8 A;  4PKS A;  1BQQ M;  1RMZ A;  1OM7 A;  4Q1L A;  5JMY A;  1KBC A;  1I1I P;  2OW1 A;  3KRY A;  1OM8 A;  1ZTQ A;  3F1A A;  3BA0 A;  3TT4 A;  2OY4 A;  5CXA A;  2SRT A;  1KUG A;  1RM8 A;  4FVL A;  4GF1 A;  4JA1 A;  2D1N A;  2Y6C A;  2OXZ A;  4AXQ A;  3HBU P;  1A86 A;  3HDB A;  3EWJ A;  3F15 A;  2DW2 A;  1KAP P;  1TVI A;  1H71 P;  2J83 A;  1SLN A;  4H49 A;  1QIA A;  1SAT A;  2XS3 A;  2AIG P;  3KEJ A;  2X3C A;  1YQY A;  2N8R A;  2YIG A;  2K9C A;  3CKI A;  1G4K A;  2V4B A;  1CK7 A;  2MZI A;  3LK8 A;  1QIB A;  2CLT A;  4IUW A;  3B8Z A;  2USN A;  4G0D A;  4H76 A;  3KME A;  2W12 A;  1ND1 A;  4AYK A;  3Q2H A;  3EDI A;  4PKT A;  1R1H A;  4PKR A;  2ERO A;  1O0T A;  1Y8J A;  1AF0 A;  1YCM A;  2Z2D A;  1B3D A;  1QJI A;  3I7I A;  1JH1 A;  1BZS A;  1XUR A;  3LJT A;  4G9L A;  4XBH A;  2ERQ A;  3HY9 A;  1D8F A;  5D7W A;  1CQR A;  1PWP A;  4CTH A;  3N2V A;  5D1T A;  3HDA P;  2QPJ A;  1Y0V A;  1HOV A;  3EDH A;  1YP1 A;  3HY7 A;  2OW9 A;  3DPF A;  5D1U A;  1QIC A;  1JKY A;  3EHY A;  1XM5 A;  1OMJ A;  4WK7 A;  4H82 A;  2OI0 A;  2DW1 A;  1Z3J A;  4JIJ A;  3HYG A;  1ZXC A;  3V96 B;  4GR0 A;  4HX3 A;  2WO8 A;  3P24 A;  5I12 A;  2OVX A;  1BKC I;  4L63 A;  1CGL A;  5B5P A;  3USN A;  3LGP A;  2L0R A;  1BKC E;  2DW0 A;  1R54 A;  4R3V A;  2ERP A;  4L19 A;  3O64 A;  3AYK A;  4EFS A;  4DV8 A;  3LEA A;  1ZXV A;  3G5C A;  3DWB A;  2JT5 A;  1K7I A;  1ZP5 A;  5I2Z A;  4DD8 A;  3F16 A;  2E3X A;  5D1S A;  3WV1 A;  3MA2 A;  3O2X A;  1JAQ A;  1OS9 A;  4GWM A;  1PWU A;  1XAX A;  3KEC A;  3LIK A;  2WOA A;  1OS2 A;  4H3X A;  2RJQ A;  4PKW A;  2MZH A;  4FXQ A;  2JT6 A;  2A8H A;  4WZV A;  4AIG A;  1Y93 A;  3I7G A;  1MMQ A;  4JPA A;  3LQ0 A;  3KWV C;  3NX7 A;  3DTE A;  2X3A A;  5I4O A; 
#chains in the Genus database with same CATH homology
 5D3C A;  1YOU A;  3HB2 P;  2TCL A;  1G12 A;  3DTI A;  2MLS A;  3WV2 A;  3ZVS A;  1C7K A;  2HU6 A;  1JIW P;  3L0T A;  2RJP A;  2OW2 A;  3LQB A;  1DMT A;  1MMP A;  1BUV M;  1XFV A;  1MNC A;  1QJJ A;  4FU4 A;  1CAQ A;  1G05 A;  2OXW A;  4ON1 A;  3ELM A;  1GE7 A;  3DNG A;  1EAK A;  1D8M A;  1JAP A;  2YUF A;  4J4M A;  2WO9 A;  1IAB A;  2X7M A;  1SLM A;  2YB9 A;  4IN9 A;  4WKI A;  1XFZ A;  4I35 A;  2CKI A;  4JP4 A;  1CXV A;  5B5O A;  1CGF A;  4IJO A;  1HTD A;  2OXU A;  1USN A;  1IAA A;  2O3E A;  1K7G A;  1ATL A;  1SRP A;  830C A;  1C3I A;  1ZVX A;  2O36 A;  1KUK A;  2Y6D A;  1MMR A;  4AUO A;  1QUA A;  1G49 A;  3VTG A;  4H30 A;  1IAD A;  1D5J A;  1I73 A;  3TS4 A;  1KUI A;  4A3W A;  2PJT A;  1K7Q A;  5BPA A;  456C A;  4L6T A;  1BIW A;  5LAB A;  1FBL A;  4ZR5 A;  2AYK A;  3TVC A;  1FM1 A;  2JSD A;  2KRJ A;  1OO9 A;  4I03 A;  5L79 A;  5D2B A;  1AKL A;  1JJ9 A;  1BUD A;  4GQL A;  1HFC A;  2K2G A;  3K7N A;  1SU3 A;  2X3B A;  4HMA A;  2J0T A;  1ZS0 A;  4H1Q A;  1J7N A;  3F18 A;  3U1R A;  3VI1 A;  5CZM A;  5I3M A;  3OHO A;  3GBO A;  2FV9 A;  1R55 A;  3SHI A;  4XM6 A;  1GE5 A;  4JQG A;  1KUH A;  3WV3 A;  4GUY A;  3AYU A;  2W0D A;  1PWV A;  3K7L A;  3LKA A;  3F19 A;  1I76 A;  4WF6 A;  1BM6 A;  1BSW A;  1PWW A;  4XM7 A;  2E2D A;  1FLS A;  3AIG A;  2JIH A;  2D1O A;  3P1V A;  4DF9 A;  3LMC A;  3LJG A;  4H2E A;  2DDF A;  1AST A;  1EB6 A;  966C A;  3Q2G A;  2OW0 A;  4PKV A;  4A7B A;  1KUF A;  2OZR A;  3E8R A;  1GKD A;  1R1J A;  5BOY A;  1L6J A;  1XFY A;  1CIZ A;  1BKC A;  2JNP A;  2POJ A;  3KHI A;  1AYK A;  1CGE A;  2W15 A;  3LIL A;  3HBV P;  3LUM A;  3DL1 A;  1GKC A;  1XFX A;  5BOT A;  1MMB A;  4XCT A;  1JK3 A;  3N2U A;  4PKU A;  4WKE A;  1EUB A;  3B2Z A;  3EDZ A;  1JAO A;  1HFS A;  3EHX A;  1A85 A;  4PKQ A;  3LIR A;  2MLR A;  1R1I A;  4DPE A;  1UMT A;  1HY7 A;  4GWN A;  3DPE A;  5L7F A;  2OY2 A;  1XUD A;  2OVZ A;  3RTT A;  2DDY A;  1G9K A;  1JIZ A;  4ILW D;  3G42 A;  3B92 A;  1O0Q A;  1UTZ A;  1HV5 A;  3KEK A;  4H84 A;  5CUH A;  3ZXH A;  1XFU A;  3OHL A;  3EDG A;  5I43 A;  2I47 A;  1UMS A;  4FXY P;  3F17 A;  1PWQ A;  1IAE A;  4XM8 A;  1UEA A;  1C8T A;  1B8Y A;  1GO7 P;  2XS4 A;  3DTK A;  3UVC A;  1OM6 A;  1ROS A;  1S4B P;  1BQO A;  3L0V A;  3LE9 A;  1GXD A;  3LJZ A;  1DTH A;  3ZUK A;  3RTS A;  5H8X A;  1WNI A;  2FV5 A;  1UTT A;  1JAN A;  1XFW A;  1Q3A A;  3DSL A;  1GE6 A;  3LUN A;  4L7A A;  1SMP A;  1GO8 P;  2W13 A;  2W14 A;  1D7X A;  1IAC A;  4GR3 A;  5I0L A;  1IAG A;  2MZE A;  3KMC A;  3TSK A;  1XUC A;  4QKZ A;  4GR8 A;  4PKS A;  1BQQ M;  1RMZ A;  1OM7 A;  4Q1L A;  5JMY A;  1KBC A;  1I1I P;  2OW1 A;  3KRY A;  1OM8 A;  1ZTQ A;  3F1A A;  3BA0 A;  3TT4 A;  2OY4 A;  5CXA A;  2SRT A;  1KUG A;  1RM8 A;  4FVL A;  4GF1 A;  4JA1 A;  2D1N A;  2Y6C A;  2OXZ A;  4AXQ A;  3HBU P;  1A86 A;  3HDB A;  3EWJ A;  3F15 A;  2DW2 A;  1KAP P;  1H71 P;  2J83 A;  1SLN A;  4H49 A;  1QIA A;  1SAT A;  2XS3 A;  2AIG P;  3KEJ A;  2X3C A;  1YQY A;  2N8R A;  2YIG A;  2K9C A;  3CKI A;  1G4K A;  2V4B A;  1CK7 A;  2MZI A;  3LK8 A;  1QIB A;  2CLT A;  4IUW A;  3B8Z A;  2USN A;  4G0D A;  4H76 A;  3KME A;  2W12 A;  1ND1 A;  4AYK A;  3Q2H A;  3EDI A;  4PKT A;  1R1H A;  4PKR A;  2ERO A;  1O0T A;  1Y8J A;  1AF0 A;  1YCM A;  2Z2D A;  1B3D A;  1QJI A;  3I7I A;  1JH1 A;  1BZS A;  1XUR A;  3LJT A;  4G9L A;  4XBH A;  2ERQ A;  3HY9 A;  1D8F A;  5D7W A;  1CQR A;  1PWP A;  4CTH A;  3N2V A;  5D1T A;  3HDA P;  2QPJ A;  1Y0V A;  1HOV A;  3EDH A;  1YP1 A;  3HY7 A;  2OW9 A;  3DPF A;  5D1U A;  1QIC A;  1JKY A;  3EHY A;  1OMJ A;  4WK7 A;  4H82 A;  2OI0 A;  2DW1 A;  1Z3J A;  4JIJ A;  3HYG A;  1ZXC A;  3V96 B;  4GR0 A;  4HX3 A;  2WO8 A;  3P24 A;  5I12 A;  2OVX A;  1BKC I;  4L63 A;  1CGL A;  5B5P A;  3USN A;  3LGP A;  2L0R A;  1BKC E;  2DW0 A;  1R54 A;  4R3V A;  2ERP A;  4L19 A;  3O64 A;  3AYK A;  4EFS A;  4DV8 A;  3LEA A;  1ZXV A;  3G5C A;  3DWB A;  2JT5 A;  1K7I A;  1ZP5 A;  5I2Z A;  4DD8 A;  3F16 A;  2E3X A;  5D1S A;  3WV1 A;  3MA2 A;  3O2X A;  1JAQ A;  1OS9 A;  4GWM A;  1PWU A;  3KEC A;  3LIK A;  2WOA A;  1OS2 A;  4H3X A;  2RJQ A;  4PKW A;  2MZH A;  4FXQ A;  2JT6 A;  2A8H A;  4WZV A;  4AIG A;  1Y93 A;  3I7G A;  1MMQ A;  4JPA A;  3LQ0 A;  3KWV C;  3NX7 A;  3DTE A;  2X3A A;  5I4O A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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