2FV5A

Crystal structure of tace in complex with ik682
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
261
structure length
261
Chain Sequence
ADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYGGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title IK682, a tight binding inhibitor of TACE.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords ADAM 17
total genus 81
structure length 261
sequence length 261
chains with identical sequence B
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2006-01-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 2fv5A00
4AIGA 3EDIA 3B92A 3LGPA 3HDAP 4GR0A 4FXYP 2K2GA 1CGLA 2W13A 4PKWA 5D1TA 4PKVA 1R1HA 2N8RA 1CGFA 1YP1A 1BUVM 1G4KA 1B3DA 1C8TA 5CXAA 1KUGA 2X3BA 3F18A 5B5PA 1C7KA 1IACA 4GR8A 1HV5A 1I73A 1PWPA 1FBLA 1OMJA 4ON1A 4JP4A 4H2EA 3ZVSA 1MNCA 5JMYA 4PKSA 2Y6CA 5BOYA 1YQYA 3I7GA 3OHOA 4DF9A 1JAOA 3DL1A 2DW0A 2OW0A 4WKEA 1QJIA 1IAGA 1BKCA 1OM7A 1R1JA 2I47A 2ERQA 3B2ZA 1BKCI 1SU3A 3OHLA 1EAKA 2AYKA 3LUNA 4H30A 3EWJA 1R55A 1MMBA 2WOAA 3LK8A 2CLTA 4PKTA 2JT6A 3TS4A 1QIAA 1Y0VA 1KBCA 3G42A 1HFCA 1EB6A 3B8ZA 4IN9A 1D7XA 2YIGA 1SMPA 3EDGA 1UMSA 4L19A 3HYGA 3HBVP 3HY7A 2O3EA 1SLNA 3HB2P 1FM1A 1KUKA 4DD8A 3CKIA 2L0RA 1MMQA 1ZP5A 4GUYA 1XFZA 1XFYA 1ASTA 3HDBA 1JJ9A 3Q2GA 830CA 2E3XA 2WO9A 2KRJA 4H49A 5D3CA 1XUDA 2MZEA 5L7FA 1BUDA 1XFWA 2W0DA 5I43A 1AF0A 2DW2A 1RM8A 2OXUA 5I2ZA 1XUCA 3L0TA 1S4BP 1PWWA 2O36A 2JIHA 1ND1A 2D1NA 2OVXA 1MMRA 4WZVA 5D1UA 2USNA 5BOTA 1BQOA 3ZXHA 1R1IA 4XM7A 1XURA 5LABA 3LKAA 3ZUKA 3BA0A 3V96B 2EROA 3DSLA 1YCMA 3K7LA 4L6TA 3LIKA 1IADA 2X3AA 4A3WA 1O0TA 3Q2HA 4ILWD 1ROSA 3LEAA 1USNA 2FV5A 4AUOA 3DNGA 4XM6A 1JAQA 1OM8A 1WNIA 3EHYA 3L0VA 3G5CA 1JIWP 3I7IA 1GXDA 4Q1LA 2W15A 1I76A 2RJQA 1OM6A 2MLRA 1Y93A 2OI0A 3HBUP 5CUHA 1GE7A 1Z3JA 5D7WA 3P24A 1GKCA 1I1IP 3F16A 4JA1A 3DPFA 1IAEA 4FXQA 4HX3A 3TT4A 4XCTA 1CQRA 4GF1A 1CGEA 4IUWA 5I4OA 1ZXCA 1Q3AA 4QKZA 2DDFA 1JKYA 3UVCA 4H1QA 2OVZA 1G12A 3F15A 4R3VA 1UEAA 3KEJA 5B5OA 1D5JA 2WO8A 3ELMA 4I35A 2XS4A 1G05A 5BPAA 1PWUA 1G9KA 5I3MA 2Y6DA 1QUAA 1XFXA 1BQQM 1BKCE 2SRTA 4WF6A 3U1RA 3N2UA 3O2XA 5D1SA 4PKRA 2OXZA 1CAQA 2OW9A 3DWBA 1CK7A 5I12A 1FLSA 1PWQA 4G9LA 4AYKA 3K7NA 2D1OA 3KWVC 4DPEA 4JIJA 3E8RA 3KECA 4XBHA 2XS3A 2AIGP 2ERPA 4DV8A 4AXQA 1AYKA 1MMPA 1PWVA 1AKLA 3EDZA 3F1AA 4H3XA 2J0TA 2MLSA 4HMAA 5CZMA 1UTTA 4GWMA 2JNPA 3GBOA 4GQLA 1A85A 4GR3A 4XM8A 5H8XA 4I03A 4GWNA 1BM6A 4IJOA 3KMCA 2POJA 2MZHA 3KHIA 1Y8JA 3DPEA 1HY7A 2W12A 4FU4A 1HTDA 4EFSA 3LIRA 1GO8P 2CKIA 3TSKA 1ZS0A 2DW1A 1XFUA 1IABA 1C3IA 1J7NA 3USNA 1OO9A 2MZIA 2OXWA 1D8FA 1H71P 1YOUA 1KUIA 4JQGA 1GKDA 3VI1A 2V4BA 3LMCA 1K7IA 1UTZA 4L63A 1R54A 4JPAA 1JANA 3HY9A 3TVCA 3KMEA 3LE9A 4G0DA 3LQBA 2A8HA 2E2DA 2JSDA 3WV2A 3AIGA 4H82A 4WKIA 1BZSA 4FVLA 4WK7A 3KRYA 1GO7P 3KEKA 1QIBA 3F17A 1O0QA 1KUFA 3VTGA 1G49A 1D8MA 2W14A 2OW1A 3LILA 1KUHA 1SRPA 3O64A 1JIZA 2PJTA 1UMTA 1ATLA 2TCLA 4A7BA 1GE5A 2QPJA 2K9CA 1DMTA 3F19A 2JT5A 1BSWA 2X3CA 1ZXVA 4J4MA 1K7GA 1GE6A 3RTSA 3RTTA 2OW2A 456CA 3LUMA 1XFVA 3AYKA 2Z2DA 2OY2A 966CA 5L79A 2DDYA 3MA2A 2FV9A 3EDHA 4ZR5A 2HU6A 5I0LA 4PKQA 3P1VA 2J83A 1ZTQA 3WV1A 3LJTA 3LQ0A 1K7QA 3SHIA 1QICA 4H84A 1QJJA 1JH1A 3AYUA 3WV3A 1IAAA 1RMZA 1CXVA 1ZVXA 2OY4A 1BIWA 1JK3A 1EUBA 3NX7A 5D2BA 1DTHA 1SLMA 3LJGA 1HFSA 4CTHA 1KAPP 1HOVA 3N2VA 2RJPA 2OZRA 1CIZA 4H76A 1JAPA 3LJZA 1A86A 1L6JA 2X7MA 1B8YA 1SATA 4PKUA 1OS2A 3EHXA 1OS9A 2YB9A
chains in the Genus database with same CATH superfamily
4AIGA 3EDIA 3B92A 3LGPA 3HDAP 4GR0A 4FXYP 2K2GA 1CGLA 2W13A 4PKWA 5D1TA 4PKVA 1R1HA 2N8RA 1CGFA 1TVIA 1YP1A 1BUVM 1G4KA 1B3DA 1C8TA 5CXAA 1KUGA 2X3BA 3F18A 5B5PA 1C7KA 1IACA 4GR8A 1HV5A 1I73A 1PWPA 1FBLA 1OMJA 4ON1A 4JP4A 4H2EA 3ZVSA 1MNCA 5JMYA 4PKSA 2Y6CA 5BOYA 1YQYA 3I7GA 3OHOA 4DF9A 1JAOA 3DL1A 2DW0A 2OW0A 4WKEA 1QJIA 1XM5A 1IAGA 1BKCA 1OM7A 1R1JA 2I47A 2ERQA 3B2ZA 1BKCI 1SU3A 3OHLA 1EAKA 2AYKA 3LUNA 4H30A 3EWJA 1R55A 1MMBA 2WOAA 3LK8A 2CLTA 4PKTA 2JT6A 3TS4A 1QIAA 1Y0VA 1KBCA 3G42A 1HFCA 1EB6A 3B8ZA 4IN9A 1OZ9A 1D7XA 2YIGA 1SMPA 3EDGA 1UMSA 4L19A 3HYGA 3HBVP 3HY7A 2O3EA 1SLNA 3HB2P 1FM1A 1KUKA 4DD8A 3CKIA 2L0RA 1MMQA 1ZP5A 4GUYA 1XFZA 1XFYA 1ASTA 3HDBA 1JJ9A 3Q2GA 830CA 2E3XA 2WO9A 2KRJA 4H49A 5D3CA 1XUDA 2MZEA 5L7FA 1BUDA 1XFWA 2W0DA 5I43A 1AF0A 2DW2A 1RM8A 2OXUA 5I2ZA 1XUCA 3L0TA 1S4BP 1PWWA 2O36A 2JIHA 1ND1A 2D1NA 2OVXA 1MMRA 4WZVA 5D1UA 2USNA 5BOTA 1BQOA 3ZXHA 1R1IA 4XM7A 1XURA 5LABA 3LKAA 3ZUKA 3DTEA 3BA0A 3V96B 2EROA 3DSLA 1YCMA 3K7LA 4L6TA 3LIKA 1IADA 2X3AA 4A3WA 1O0TA 3Q2HA 4ILWD 1ROSA 3LEAA 1USNA 2FV5A 4AUOA 3DNGA 4XM6A 1JAQA 1OM8A 1WNIA 3EHYA 3L0VA 3G5CA 1JIWP 3I7IA 1GXDA 4Q1LA 2W15A 1I76A 2RJQA 1OM6A 2MLRA 1Y93A 2OI0A 3HBUP 5CUHA 1GE7A 1Z3JA 5D7WA 3P24A 1GKCA 1I1IP 3F16A 4JA1A 3DPFA 1IAEA 4FXQA 4HX3A 3TT4A 4XCTA 1CQRA 3DTKA 4GF1A 1CGEA 4IUWA 5I4OA 1ZXCA 1XAXA 1Q3AA 4QKZA 2DDFA 1JKYA 3UVCA 4H1QA 2OVZA 1G12A 3F15A 4R3VA 1UEAA 3KEJA 5B5OA 1D5JA 2WO8A 3ELMA 4I35A 2XS4A 1G05A 5BPAA 1PWUA 1G9KA 5I3MA 2Y6DA 1QUAA 1XFXA 1BQQM 1BKCE 2SRTA 4WF6A 3U1RA 3N2UA 3O2XA 5D1SA 4PKRA 2OXZA 1CAQA 2OW9A 3DWBA 1CK7A 5I12A 1FLSA 1PWQA 4G9LA 4AYKA 3K7NA 2D1OA 3KWVC 4DPEA 4JIJA 3E8RA 3KECA 4XBHA 2XS3A 2AIGP 2ERPA 4DV8A 4AXQA 1AYKA 1MMPA 1PWVA 1AKLA 3EDZA 3F1AA 4H3XA 2J0TA 2MLSA 4HMAA 5CZMA 1UTTA 3DTIA 4GWMA 2JNPA 3GBOA 4GQLA 1A85A 4GR3A 4XM8A 5H8XA 4I03A 4GWNA 1BM6A 4IJOA 3KMCA 2POJA 2MZHA 3KHIA 1Y8JA 3DPEA 1HY7A 2W12A 4FU4A 1HTDA 4EFSA 3LIRA 1GO8P 2CKIA 3TSKA 1ZS0A 2DW1A 1XFUA 1IABA 1C3IA 1J7NA 3USNA 1OO9A 2MZIA 2OXWA 1D8FA 1H71P 1YOUA 1KUIA 4JQGA 1GKDA 3VI1A 2V4BA 3LMCA 1K7IA 1UTZA 4L63A 1R54A 4JPAA 1JANA 3HY9A 3TVCA 3KMEA 3LE9A 4G0DA 3LQBA 2A8HA 2E2DA 2JSDA 3WV2A 3AIGA 4H82A 4WKIA 1BZSA 4FVLA 4WK7A 3KRYA 1GO7P 3KEKA 4L7AA 1QIBA 3F17A 1O0QA 1KUFA 3VTGA 1G49A 1D8MA 2W14A 2OW1A 3LILA 1KUHA 1SRPA 3O64A 1JIZA 2PJTA 1UMTA 1ATLA 2TCLA 4A7BA 1GE5A 2QPJA 2K9CA 1DMTA 3F19A 2JT5A 1BSWA 2X3CA 1ZXVA 4J4MA 1K7GA 1GE6A 3RTSA 3RTTA 2OW2A 456CA 3LUMA 1XFVA 3AYKA 2Z2DA 2OY2A 966CA 5L79A 2DDYA 3MA2A 2FV9A 3EDHA 4ZR5A 2HU6A 5I0LA 4PKQA 3P1VA 2J83A 1ZTQA 3WV1A 3LJTA 3LQ0A 1K7QA 3SHIA 1QICA 4H84A 1QJJA 1JH1A 3AYUA 3WV3A 1IAAA 1RMZA 1CXVA 1ZVXA 2OY4A 1BIWA 1JK3A 1EUBA 3NX7A 5D2BA 1DTHA 1SLMA 3LJGA 1HFSA 4CTHA 1KAPP 1HOVA 3N2VA 2RJPA 2OZRA 1CIZA 4H76A 1JAPA 3LJZA 2YUFA 1A86A 1L6JA 2X7MA 1B8YA 1SATA 4PKUA 1OS2A 3EHXA 1OS9A 2YB9A
chains in the Genus database with same CATH topology
4AIGA 3EDIA 3B92A 3LGPA 3HDAP 4GR0A 4FXYP 2K2GA 1CGLA 2W13A 4PKWA 5D1TA 4PKVA 1R1HA 2N8RA 1CGFA 1YP1A 1BUVM 1G4KA 1B3DA 1C8TA 5CXAA 1KUGA 2X3BA 3F18A 5B5PA 1C7KA 1IACA 4GR8A 1HV5A 1I73A 1PWPA 1FBLA 1OMJA 4ON1A 4JP4A 4H2EA 3ZVSA 1MNCA 5JMYA 4PKSA 2Y6CA 5BOYA 1YQYA 3I7GA 3OHOA 4DF9A 1JAOA 3DL1A 2DW0A 2OW0A 4WKEA 1QJIA 1IAGA 1BKCA 1OM7A 1R1JA 2I47A 2ERQA 3B2ZA 1BKCI 1SU3A 3OHLA 1EAKA 2AYKA 3LUNA 4H30A 3EWJA 1R55A 1MMBA 2WOAA 3LK8A 2CLTA 4PKTA 2JT6A 3TS4A 1QIAA 1Y0VA 1KBCA 3G42A 1HFCA 1EB6A 3B8ZA 4IN9A 1D7XA 2YIGA 1SMPA 3EDGA 1UMSA 4L19A 3HYGA 3HBVP 3HY7A 2O3EA 1SLNA 3HB2P 1FM1A 1KUKA 4DD8A 3CKIA 2L0RA 1MMQA 1ZP5A 4GUYA 1XFZA 1XFYA 1ASTA 3HDBA 1JJ9A 3Q2GA 830CA 2E3XA 2WO9A 2KRJA 4H49A 5D3CA 1XUDA 2MZEA 5L7FA 1BUDA 1XFWA 2W0DA 5I43A 1AF0A 2DW2A 1RM8A 2OXUA 5I2ZA 1XUCA 3L0TA 1S4BP 1PWWA 2O36A 2JIHA 1ND1A 2D1NA 2OVXA 1MMRA 4WZVA 5D1UA 2USNA 5BOTA 1BQOA 3ZXHA 1R1IA 4XM7A 1XURA 5LABA 3LKAA 3ZUKA 3DTEA 3BA0A 3V96B 2EROA 3DSLA 1YCMA 3K7LA 4L6TA 3LIKA 1IADA 2X3AA 4A3WA 1O0TA 3Q2HA 4ILWD 1ROSA 3LEAA 1USNA 2FV5A 4AUOA 3DNGA 4XM6A 1JAQA 1OM8A 1WNIA 3EHYA 3L0VA 3G5CA 1JIWP 3I7IA 1GXDA 4Q1LA 2W15A 1I76A 2RJQA 1OM6A 2MLRA 1Y93A 2OI0A 3HBUP 5CUHA 1GE7A 1Z3JA 5D7WA 3P24A 1GKCA 1I1IP 3F16A 4JA1A 3DPFA 1IAEA 4FXQA 4HX3A 3TT4A 4XCTA 1CQRA 3DTKA 4GF1A 1CGEA 4IUWA 5I4OA 1ZXCA 1Q3AA 4QKZA 2DDFA 1JKYA 3UVCA 4H1QA 2OVZA 1G12A 3F15A 4R3VA 1UEAA 3KEJA 5B5OA 1D5JA 2WO8A 3ELMA 4I35A 2XS4A 1G05A 5BPAA 1PWUA 1G9KA 5I3MA 2Y6DA 1QUAA 1XFXA 1BQQM 1BKCE 2SRTA 4WF6A 3U1RA 3N2UA 3O2XA 5D1SA 4PKRA 2OXZA 1CAQA 2OW9A 3DWBA 1CK7A 5I12A 1FLSA 1PWQA 4G9LA 4AYKA 3K7NA 2D1OA 3KWVC 4DPEA 4JIJA 3E8RA 3KECA 4XBHA 2XS3A 2AIGP 2ERPA 4DV8A 4AXQA 1AYKA 1MMPA 1PWVA 1AKLA 3EDZA 3F1AA 4H3XA 2J0TA 2MLSA 4HMAA 5CZMA 1UTTA 3DTIA 4GWMA 2JNPA 3GBOA 4GQLA 1A85A 4GR3A 4XM8A 5H8XA 4I03A 4GWNA 1BM6A 4IJOA 3KMCA 2POJA 2MZHA 3KHIA 1Y8JA 3DPEA 1HY7A 2W12A 4FU4A 1HTDA 4EFSA 3LIRA 1GO8P 2CKIA 3TSKA 1ZS0A 2DW1A 1XFUA 1IABA 1C3IA 1J7NA 3USNA 1OO9A 2MZIA 2OXWA 1D8FA 1H71P 1YOUA 1KUIA 4JQGA 1GKDA 3VI1A 2V4BA 3LMCA 1K7IA 1UTZA 4L63A 1R54A 4JPAA 1JANA 3HY9A 3TVCA 3KMEA 3LE9A 4G0DA 3LQBA 2A8HA 2E2DA 2JSDA 3WV2A 3AIGA 4H82A 4WKIA 1BZSA 4FVLA 4WK7A 3KRYA 1GO7P 3KEKA 4L7AA 1QIBA 3F17A 1O0QA 1KUFA 3VTGA 1G49A 1D8MA 2W14A 2OW1A 3LILA 1KUHA 1SRPA 3O64A 1JIZA 2PJTA 1UMTA 1ATLA 2TCLA 4A7BA 1GE5A 2QPJA 2K9CA 1DMTA 3F19A 2JT5A 1BSWA 2X3CA 1ZXVA 4J4MA 1K7GA 1GE6A 3RTSA 3RTTA 2OW2A 456CA 3LUMA 1XFVA 3AYKA 2Z2DA 2OY2A 966CA 5L79A 2DDYA 3MA2A 2FV9A 3EDHA 4ZR5A 2HU6A 5I0LA 4PKQA 3P1VA 2J83A 1ZTQA 3WV1A 3LJTA 3LQ0A 1K7QA 3SHIA 1QICA 4H84A 1QJJA 1JH1A 3AYUA 3WV3A 1IAAA 1RMZA 1CXVA 1ZVXA 2OY4A 1BIWA 1JK3A 1EUBA 3NX7A 5D2BA 1DTHA 1SLMA 3LJGA 1HFSA 4CTHA 1KAPP 1HOVA 3N2VA 2RJPA 2OZRA 1CIZA 4H76A 1JAPA 3LJZA 2YUFA 1A86A 1L6JA 2X7MA 1B8YA 1SATA 4PKUA 1OS2A 3EHXA 1OS9A 2YB9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AIG A;  3EDI A;  3B92 A;  3LGP A;  3HDA P;  4GR0 A;  4FXY P;  2K2G A;  1CGL A;  2W13 A;  4PKW A;  5D1T A;  4PKV A;  1R1H A;  2N8R A;  1CGF A;  1YP1 A;  1BUV M;  1G4K A;  1B3D A;  1C8T A;  5CXA A;  1KUG A;  2X3B A;  3F18 A;  5B5P A;  1C7K A;  1IAC A;  4GR8 A;  1HV5 A;  1I73 A;  1PWP A;  1FBL A;  1OMJ A;  4ON1 A;  4JP4 A;  4H2E A;  3ZVS A;  1MNC A;  5JMY A;  4PKS A;  2Y6C A;  5BOY A;  1YQY A;  3I7G A;  3OHO A;  4DF9 A;  1JAO A;  3DL1 A;  2DW0 A;  2OW0 A;  4WKE A;  1QJI A;  1IAG A;  1BKC A;  1OM7 A;  1R1J A;  2I47 A;  2ERQ A;  3B2Z A;  1BKC I;  1SU3 A;  3OHL A;  1EAK A;  2AYK A;  3LUN A;  4H30 A;  3EWJ A;  1R55 A;  1MMB A;  2WOA A;  3LK8 A;  2CLT A;  4PKT A;  2JT6 A;  3TS4 A;  1QIA A;  1Y0V A;  1KBC A;  3G42 A;  1HFC A;  1EB6 A;  3B8Z A;  4IN9 A;  1D7X A;  2YIG A;  1SMP A;  3EDG A;  1UMS A;  4L19 A;  3HYG A;  3HBV P;  3HY7 A;  2O3E A;  1SLN A;  3HB2 P;  1FM1 A;  1KUK A;  4DD8 A;  3CKI A;  2L0R A;  1MMQ A;  1ZP5 A;  4GUY A;  1XFZ A;  1XFY A;  1AST A;  3HDB A;  1JJ9 A;  3Q2G A;  830C A;  2E3X A;  2WO9 A;  2KRJ A;  4H49 A;  5D3C A;  1XUD A;  2MZE A;  5L7F A;  1BUD A;  1XFW A;  2W0D A;  5I43 A;  1AF0 A;  2DW2 A;  1RM8 A;  2OXU A;  5I2Z A;  1XUC A;  3L0T A;  1S4B P;  1PWW A;  2O36 A;  2JIH A;  1ND1 A;  2D1N A;  2OVX A;  1MMR A;  4WZV A;  5D1U A;  2USN A;  5BOT A;  1BQO A;  3ZXH A;  1R1I A;  4XM7 A;  1XUR A;  5LAB A;  3LKA A;  3ZUK A;  3BA0 A;  3V96 B;  2ERO A;  3DSL A;  1YCM A;  3K7L A;  4L6T A;  3LIK A;  1IAD A;  2X3A A;  4A3W A;  1O0T A;  3Q2H A;  4ILW D;  1ROS A;  3LEA A;  1USN A;  2FV5 A;  4AUO A;  3DNG A;  4XM6 A;  1JAQ A;  1OM8 A;  1WNI A;  3EHY A;  3L0V A;  3G5C A;  1JIW P;  3I7I A;  1GXD A;  4Q1L A;  2W15 A;  1I76 A;  2RJQ A;  1OM6 A;  2MLR A;  1Y93 A;  2OI0 A;  3HBU P;  5CUH A;  1GE7 A;  1Z3J A;  5D7W A;  3P24 A;  1GKC A;  1I1I P;  3F16 A;  4JA1 A;  3DPF A;  1IAE A;  4FXQ A;  4HX3 A;  3TT4 A;  4XCT A;  1CQR A;  4GF1 A;  1CGE A;  4IUW A;  5I4O A;  1ZXC A;  1Q3A A;  4QKZ A;  2DDF A;  1JKY A;  3UVC A;  4H1Q A;  2OVZ A;  1G12 A;  3F15 A;  4R3V A;  1UEA A;  3KEJ A;  5B5O A;  1D5J A;  2WO8 A;  3ELM A;  4I35 A;  2XS4 A;  1G05 A;  5BPA A;  1PWU A;  1G9K A;  5I3M A;  2Y6D A;  1QUA A;  1XFX A;  1BQQ M;  1BKC E;  2SRT A;  4WF6 A;  3U1R A;  3N2U A;  3O2X A;  5D1S A;  4PKR A;  2OXZ A;  1CAQ A;  2OW9 A;  3DWB A;  1CK7 A;  5I12 A;  1FLS A;  1PWQ A;  4G9L A;  4AYK A;  3K7N A;  2D1O A;  3KWV C;  4DPE A;  4JIJ A;  3E8R A;  3KEC A;  4XBH A;  2XS3 A;  2AIG P;  2ERP A;  4DV8 A;  4AXQ A;  1AYK A;  1MMP A;  1PWV A;  1AKL A;  3EDZ A;  3F1A A;  4H3X A;  2J0T A;  2MLS A;  4HMA A;  5CZM A;  1UTT A;  4GWM A;  2JNP A;  3GBO A;  4GQL A;  1A85 A;  4GR3 A;  4XM8 A;  5H8X A;  4I03 A;  4GWN A;  1BM6 A;  4IJO A;  3KMC A;  2POJ A;  2MZH A;  3KHI A;  1Y8J A;  3DPE A;  1HY7 A;  2W12 A;  4FU4 A;  1HTD A;  4EFS A;  3LIR A;  1GO8 P;  2CKI A;  3TSK A;  1ZS0 A;  2DW1 A;  1XFU A;  1IAB A;  1C3I A;  1J7N A;  3USN A;  1OO9 A;  2MZI A;  2OXW A;  1D8F A;  1H71 P;  1YOU A;  1KUI A;  4JQG A;  1GKD A;  3VI1 A;  2V4B A;  3LMC A;  1K7I A;  1UTZ A;  4L63 A;  1R54 A;  4JPA A;  1JAN A;  3HY9 A;  3TVC A;  3KME A;  3LE9 A;  4G0D A;  3LQB A;  2A8H A;  2E2D A;  2JSD A;  3WV2 A;  3AIG A;  4H82 A;  4WKI A;  1BZS A;  4FVL A;  4WK7 A;  3KRY A;  1GO7 P;  3KEK A;  1QIB A;  3F17 A;  1O0Q A;  1KUF A;  3VTG A;  1G49 A;  1D8M A;  2W14 A;  2OW1 A;  3LIL A;  1KUH A;  1SRP A;  3O64 A;  1JIZ A;  2PJT A;  1UMT A;  1ATL A;  2TCL A;  4A7B A;  1GE5 A;  2QPJ A;  2K9C A;  1DMT A;  3F19 A;  2JT5 A;  1BSW A;  2X3C A;  1ZXV A;  4J4M A;  1K7G A;  1GE6 A;  3RTS A;  3RTT A;  2OW2 A;  456C A;  3LUM A;  1XFV A;  3AYK A;  2Z2D A;  2OY2 A;  966C A;  5L79 A;  2DDY A;  3MA2 A;  2FV9 A;  3EDH A;  4ZR5 A;  2HU6 A;  5I0L A;  4PKQ A;  3P1V A;  2J83 A;  1ZTQ A;  3WV1 A;  3LJT A;  3LQ0 A;  1K7Q A;  3SHI A;  1QIC A;  4H84 A;  1QJJ A;  1JH1 A;  3AYU A;  3WV3 A;  1IAA A;  1RMZ A;  1CXV A;  1ZVX A;  2OY4 A;  1BIW A;  1JK3 A;  1EUB A;  3NX7 A;  5D2B A;  1DTH A;  1SLM A;  3LJG A;  1HFS A;  4CTH A;  1KAP P;  1HOV A;  3N2V A;  2RJP A;  2OZR A;  1CIZ A;  4H76 A;  1JAP A;  3LJZ A;  1A86 A;  1L6J A;  2X7M A;  1B8Y A;  1SAT A;  4PKU A;  1OS2 A;  3EHX A;  1OS9 A;  2YB9 A; 
#chains in the Genus database with same CATH topology
 4AIG A;  3EDI A;  3B92 A;  3LGP A;  3HDA P;  4GR0 A;  4FXY P;  2K2G A;  1CGL A;  2W13 A;  4PKW A;  5D1T A;  4PKV A;  1R1H A;  2N8R A;  1CGF A;  1TVI A;  1YP1 A;  1BUV M;  1G4K A;  1B3D A;  1C8T A;  5CXA A;  1KUG A;  2X3B A;  3F18 A;  5B5P A;  1C7K A;  1IAC A;  4GR8 A;  1HV5 A;  1I73 A;  1PWP A;  1FBL A;  1OMJ A;  4ON1 A;  4JP4 A;  4H2E A;  3ZVS A;  1MNC A;  5JMY A;  4PKS A;  2Y6C A;  5BOY A;  1YQY A;  3I7G A;  3OHO A;  4DF9 A;  1JAO A;  3DL1 A;  2DW0 A;  2OW0 A;  4WKE A;  1QJI A;  1XM5 A;  1IAG A;  1BKC A;  1OM7 A;  1R1J A;  2I47 A;  2ERQ A;  3B2Z A;  1BKC I;  1SU3 A;  3OHL A;  1EAK A;  2AYK A;  3LUN A;  4H30 A;  3EWJ A;  1R55 A;  1MMB A;  2WOA A;  3LK8 A;  2CLT A;  4PKT A;  2JT6 A;  3TS4 A;  1QIA A;  1Y0V A;  1KBC A;  3G42 A;  1HFC A;  1EB6 A;  3B8Z A;  4IN9 A;  1OZ9 A;  1D7X A;  2YIG A;  1SMP A;  3EDG A;  1UMS A;  4L19 A;  3HYG A;  3HBV P;  3HY7 A;  2O3E A;  1SLN A;  3HB2 P;  1FM1 A;  1KUK A;  4DD8 A;  3CKI A;  2L0R A;  1MMQ A;  1ZP5 A;  4GUY A;  1XFZ A;  1XFY A;  1AST A;  3HDB A;  1JJ9 A;  3Q2G A;  830C A;  2E3X A;  2WO9 A;  2KRJ A;  4H49 A;  5D3C A;  1XUD A;  2MZE A;  5L7F A;  1BUD A;  1XFW A;  2W0D A;  5I43 A;  1AF0 A;  2DW2 A;  1RM8 A;  2OXU A;  5I2Z A;  1XUC A;  3L0T A;  1S4B P;  1PWW A;  2O36 A;  2JIH A;  1ND1 A;  2D1N A;  2OVX A;  1MMR A;  4WZV A;  5D1U A;  2USN A;  5BOT A;  1BQO A;  3ZXH A;  1R1I A;  4XM7 A;  1XUR A;  5LAB A;  3LKA A;  3ZUK A;  3DTE A;  3BA0 A;  3V96 B;  2ERO A;  3DSL A;  1YCM A;  3K7L A;  4L6T A;  3LIK A;  1IAD A;  2X3A A;  4A3W A;  1O0T A;  3Q2H A;  4ILW D;  1ROS A;  3LEA A;  1USN A;  2FV5 A;  4AUO A;  3DNG A;  4XM6 A;  1JAQ A;  1OM8 A;  1WNI A;  3EHY A;  3L0V A;  3G5C A;  1JIW P;  3I7I A;  1GXD A;  4Q1L A;  2W15 A;  1I76 A;  2RJQ A;  1OM6 A;  2MLR A;  1Y93 A;  2OI0 A;  3HBU P;  5CUH A;  1GE7 A;  1Z3J A;  5D7W A;  3P24 A;  1GKC A;  1I1I P;  3F16 A;  4JA1 A;  3DPF A;  1IAE A;  4FXQ A;  4HX3 A;  3TT4 A;  4XCT A;  1CQR A;  3DTK A;  4GF1 A;  1CGE A;  4IUW A;  5I4O A;  1ZXC A;  1XAX A;  1Q3A A;  4QKZ A;  2DDF A;  1JKY A;  3UVC A;  4H1Q A;  2OVZ A;  1G12 A;  3F15 A;  4R3V A;  1UEA A;  3KEJ A;  5B5O A;  1D5J A;  2WO8 A;  3ELM A;  4I35 A;  2XS4 A;  1G05 A;  5BPA A;  1PWU A;  1G9K A;  5I3M A;  2Y6D A;  1QUA A;  1XFX A;  1BQQ M;  1BKC E;  2SRT A;  4WF6 A;  3U1R A;  3N2U A;  3O2X A;  5D1S A;  4PKR A;  2OXZ A;  1CAQ A;  2OW9 A;  3DWB A;  1CK7 A;  5I12 A;  1FLS A;  1PWQ A;  4G9L A;  4AYK A;  3K7N A;  2D1O A;  3KWV C;  4DPE A;  4JIJ A;  3E8R A;  3KEC A;  4XBH A;  2XS3 A;  2AIG P;  2ERP A;  4DV8 A;  4AXQ A;  1AYK A;  1MMP A;  1PWV A;  1AKL A;  3EDZ A;  3F1A A;  4H3X A;  2J0T A;  2MLS A;  4HMA A;  5CZM A;  1UTT A;  3DTI A;  4GWM A;  2JNP A;  3GBO A;  4GQL A;  1A85 A;  4GR3 A;  4XM8 A;  5H8X A;  4I03 A;  4GWN A;  1BM6 A;  4IJO A;  3KMC A;  2POJ A;  2MZH A;  3KHI A;  1Y8J A;  3DPE A;  1HY7 A;  2W12 A;  4FU4 A;  1HTD A;  4EFS A;  3LIR A;  1GO8 P;  2CKI A;  3TSK A;  1ZS0 A;  2DW1 A;  1XFU A;  1IAB A;  1C3I A;  1J7N A;  3USN A;  1OO9 A;  2MZI A;  2OXW A;  1D8F A;  1H71 P;  1YOU A;  1KUI A;  4JQG A;  1GKD A;  3VI1 A;  2V4B A;  3LMC A;  1K7I A;  1UTZ A;  4L63 A;  1R54 A;  4JPA A;  1JAN A;  3HY9 A;  3TVC A;  3KME A;  3LE9 A;  4G0D A;  3LQB A;  2A8H A;  2E2D A;  2JSD A;  3WV2 A;  3AIG A;  4H82 A;  4WKI A;  1BZS A;  4FVL A;  4WK7 A;  3KRY A;  1GO7 P;  3KEK A;  4L7A A;  1QIB A;  3F17 A;  1O0Q A;  1KUF A;  3VTG A;  1G49 A;  1D8M A;  2W14 A;  2OW1 A;  3LIL A;  1KUH A;  1SRP A;  3O64 A;  1JIZ A;  2PJT A;  1UMT A;  1ATL A;  2TCL A;  4A7B A;  1GE5 A;  2QPJ A;  2K9C A;  1DMT A;  3F19 A;  2JT5 A;  1BSW A;  2X3C A;  1ZXV A;  4J4M A;  1K7G A;  1GE6 A;  3RTS A;  3RTT A;  2OW2 A;  456C A;  3LUM A;  1XFV A;  3AYK A;  2Z2D A;  2OY2 A;  966C A;  5L79 A;  2DDY A;  3MA2 A;  2FV9 A;  3EDH A;  4ZR5 A;  2HU6 A;  5I0L A;  4PKQ A;  3P1V A;  2J83 A;  1ZTQ A;  3WV1 A;  3LJT A;  3LQ0 A;  1K7Q A;  3SHI A;  1QIC A;  4H84 A;  1QJJ A;  1JH1 A;  3AYU A;  3WV3 A;  1IAA A;  1RMZ A;  1CXV A;  1ZVX A;  2OY4 A;  1BIW A;  1JK3 A;  1EUB A;  3NX7 A;  5D2B A;  1DTH A;  1SLM A;  3LJG A;  1HFS A;  4CTH A;  1KAP P;  1HOV A;  3N2V A;  2RJP A;  2OZR A;  1CIZ A;  4H76 A;  1JAP A;  3LJZ A;  2YUF A;  1A86 A;  1L6J A;  2X7M A;  1B8Y A;  1SAT A;  4PKU A;  1OS2 A;  3EHX A;  1OS9 A;  2YB9 A; 
#chains in the Genus database with same CATH homology
 4AIG A;  3EDI A;  3B92 A;  3LGP A;  3HDA P;  4GR0 A;  4FXY P;  2K2G A;  1CGL A;  2W13 A;  4PKW A;  5D1T A;  4PKV A;  1R1H A;  2N8R A;  1CGF A;  1YP1 A;  1BUV M;  1G4K A;  1B3D A;  1C8T A;  5CXA A;  1KUG A;  2X3B A;  3F18 A;  5B5P A;  1C7K A;  1IAC A;  4GR8 A;  1HV5 A;  1I73 A;  1PWP A;  1FBL A;  1OMJ A;  4ON1 A;  4JP4 A;  4H2E A;  3ZVS A;  1MNC A;  5JMY A;  4PKS A;  2Y6C A;  5BOY A;  1YQY A;  3I7G A;  3OHO A;  4DF9 A;  1JAO A;  3DL1 A;  2DW0 A;  2OW0 A;  4WKE A;  1QJI A;  1IAG A;  1BKC A;  1OM7 A;  1R1J A;  2I47 A;  2ERQ A;  3B2Z A;  1BKC I;  1SU3 A;  3OHL A;  1EAK A;  2AYK A;  3LUN A;  4H30 A;  3EWJ A;  1R55 A;  1MMB A;  2WOA A;  3LK8 A;  2CLT A;  4PKT A;  2JT6 A;  3TS4 A;  1QIA A;  1Y0V A;  1KBC A;  3G42 A;  1HFC A;  1EB6 A;  3B8Z A;  4IN9 A;  1D7X A;  2YIG A;  1SMP A;  3EDG A;  1UMS A;  4L19 A;  3HYG A;  3HBV P;  3HY7 A;  2O3E A;  1SLN A;  3HB2 P;  1FM1 A;  1KUK A;  4DD8 A;  3CKI A;  2L0R A;  1MMQ A;  1ZP5 A;  4GUY A;  1XFZ A;  1XFY A;  1AST A;  3HDB A;  1JJ9 A;  3Q2G A;  830C A;  2E3X A;  2WO9 A;  2KRJ A;  4H49 A;  5D3C A;  1XUD A;  2MZE A;  5L7F A;  1BUD A;  1XFW A;  2W0D A;  5I43 A;  1AF0 A;  2DW2 A;  1RM8 A;  2OXU A;  5I2Z A;  1XUC A;  3L0T A;  1S4B P;  1PWW A;  2O36 A;  2JIH A;  1ND1 A;  2D1N A;  2OVX A;  1MMR A;  4WZV A;  5D1U A;  2USN A;  5BOT A;  1BQO A;  3ZXH A;  1R1I A;  4XM7 A;  1XUR A;  5LAB A;  3LKA A;  3ZUK A;  3DTE A;  3BA0 A;  3V96 B;  2ERO A;  3DSL A;  1YCM A;  3K7L A;  4L6T A;  3LIK A;  1IAD A;  2X3A A;  4A3W A;  1O0T A;  3Q2H A;  4ILW D;  1ROS A;  3LEA A;  1USN A;  2FV5 A;  4AUO A;  3DNG A;  4XM6 A;  1JAQ A;  1OM8 A;  1WNI A;  3EHY A;  3L0V A;  3G5C A;  1JIW P;  3I7I A;  1GXD A;  4Q1L A;  2W15 A;  1I76 A;  2RJQ A;  1OM6 A;  2MLR A;  1Y93 A;  2OI0 A;  3HBU P;  5CUH A;  1GE7 A;  1Z3J A;  5D7W A;  3P24 A;  1GKC A;  1I1I P;  3F16 A;  4JA1 A;  3DPF A;  1IAE A;  4FXQ A;  4HX3 A;  3TT4 A;  4XCT A;  1CQR A;  3DTK A;  4GF1 A;  1CGE A;  4IUW A;  5I4O A;  1ZXC A;  1Q3A A;  4QKZ A;  2DDF A;  1JKY A;  3UVC A;  4H1Q A;  2OVZ A;  1G12 A;  3F15 A;  4R3V A;  1UEA A;  3KEJ A;  5B5O A;  1D5J A;  2WO8 A;  3ELM A;  4I35 A;  2XS4 A;  1G05 A;  5BPA A;  1PWU A;  1G9K A;  5I3M A;  2Y6D A;  1QUA A;  1XFX A;  1BQQ M;  1BKC E;  2SRT A;  4WF6 A;  3U1R A;  3N2U A;  3O2X A;  5D1S A;  4PKR A;  2OXZ A;  1CAQ A;  2OW9 A;  3DWB A;  1CK7 A;  5I12 A;  1FLS A;  1PWQ A;  4G9L A;  4AYK A;  3K7N A;  2D1O A;  3KWV C;  4DPE A;  4JIJ A;  3E8R A;  3KEC A;  4XBH A;  2XS3 A;  2AIG P;  2ERP A;  4DV8 A;  4AXQ A;  1AYK A;  1MMP A;  1PWV A;  1AKL A;  3EDZ A;  3F1A A;  4H3X A;  2J0T A;  2MLS A;  4HMA A;  5CZM A;  1UTT A;  3DTI A;  4GWM A;  2JNP A;  3GBO A;  4GQL A;  1A85 A;  4GR3 A;  4XM8 A;  5H8X A;  4I03 A;  4GWN A;  1BM6 A;  4IJO A;  3KMC A;  2POJ A;  2MZH A;  3KHI A;  1Y8J A;  3DPE A;  1HY7 A;  2W12 A;  4FU4 A;  1HTD A;  4EFS A;  3LIR A;  1GO8 P;  2CKI A;  3TSK A;  1ZS0 A;  2DW1 A;  1XFU A;  1IAB A;  1C3I A;  1J7N A;  3USN A;  1OO9 A;  2MZI A;  2OXW A;  1D8F A;  1H71 P;  1YOU A;  1KUI A;  4JQG A;  1GKD A;  3VI1 A;  2V4B A;  3LMC A;  1K7I A;  1UTZ A;  4L63 A;  1R54 A;  4JPA A;  1JAN A;  3HY9 A;  3TVC A;  3KME A;  3LE9 A;  4G0D A;  3LQB A;  2A8H A;  2E2D A;  2JSD A;  3WV2 A;  3AIG A;  4H82 A;  4WKI A;  1BZS A;  4FVL A;  4WK7 A;  3KRY A;  1GO7 P;  3KEK A;  4L7A A;  1QIB A;  3F17 A;  1O0Q A;  1KUF A;  3VTG A;  1G49 A;  1D8M A;  2W14 A;  2OW1 A;  3LIL A;  1KUH A;  1SRP A;  3O64 A;  1JIZ A;  2PJT A;  1UMT A;  1ATL A;  2TCL A;  4A7B A;  1GE5 A;  2QPJ A;  2K9C A;  1DMT A;  3F19 A;  2JT5 A;  1BSW A;  2X3C A;  1ZXV A;  4J4M A;  1K7G A;  1GE6 A;  3RTS A;  3RTT A;  2OW2 A;  456C A;  3LUM A;  1XFV A;  3AYK A;  2Z2D A;  2OY2 A;  966C A;  5L79 A;  2DDY A;  3MA2 A;  2FV9 A;  3EDH A;  4ZR5 A;  2HU6 A;  5I0L A;  4PKQ A;  3P1V A;  2J83 A;  1ZTQ A;  3WV1 A;  3LJT A;  3LQ0 A;  1K7Q A;  3SHI A;  1QIC A;  4H84 A;  1QJJ A;  1JH1 A;  3AYU A;  3WV3 A;  1IAA A;  1RMZ A;  1CXV A;  1ZVX A;  2OY4 A;  1BIW A;  1JK3 A;  1EUB A;  3NX7 A;  5D2B A;  1DTH A;  1SLM A;  3LJG A;  1HFS A;  4CTH A;  1KAP P;  1HOV A;  3N2V A;  2RJP A;  2OZR A;  1CIZ A;  4H76 A;  1JAP A;  3LJZ A;  2YUF A;  1A86 A;  1L6J A;  2X7M A;  1B8Y A;  1SAT A;  4PKU A;  1OS2 A;  3EHX A;  1OS9 A;  2YB9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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