2I47A

Crystal structure of catalytic domain of tace with inhibitor
Total Genus 84
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
84
sequence length
255
structure length
255
Chain Sequence
PMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Identification of potent and selective TACE inhibitors via the S1 pocket.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords ADAM 17
total genus 84
structure length 255
sequence length 255
chains with identical sequence B, C, D
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2006-08-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 2i47A00
3LILA 1Z3JA 4WKIA 4H49A 1AF0A 2I47A 2X3AA 1MMBA 3DWBA 3WV1A 1XURA 1BKCE 3LEAA 4ON1A 3TSKA 1JIWP 1G05A 1XUDA 4PKWA 3KECA 1RMZA 2L0RA 3HDBA 4EFSA 3F18A 1BUVM 3LQ0A 2OXZA 3GBOA 1OO9A 3TS4A 1FBLA 3O2XA 1YQYA 1KAPP 3K7LA 2MLSA 2EROA 5I4OA 1YOUA 3TT4A 2DW1A 1KUGA 2W12A 3SHIA 4DD8A 1L6JA 3VI1A 4XM8A 1XUCA 1OMJA 1BSWA 1G9KA 2OVXA 5CUHA 4CTHA 456CA 5I0LA 3WV3A 1JH1A 4FVLA 1GKCA 4JIJA 5LABA 2RJPA 4A7BA 2OI0A 5D3CA 1D8MA 1BM6A 4QKZA 3Q2GA 1D5JA 2MZEA 3LJZA 3F1AA 3I7GA 1OM6A 3ELMA 1R55A 1B3DA 1XFZA 3EDIA 1HY7A 1SATA 1O0QA 3KHIA 1GO8P 4H82A 3OHOA 2JNPA 1PWUA 1CXVA 3HDAP 1MMQA 2CKIA 1KUFA 4PKSA 1IAGA 4A3WA 3EHYA 1I76A 1PWQA 4GQLA 2O36A 1QUAA 1JAOA 5L7FA 2Z2DA 1ND1A 1GE6A 4FXYP 1GE5A 2ERQA 1JJ9A 1KBCA 1R1JA 2FV9A 4GR0A 2J83A 1GE7A 1ZVXA 1MNCA 2N8RA 2PJTA 4H76A 1O0TA 4AUOA 1EB6A 3DSLA 4GR3A 5L79A 1EUBA 2USNA 3B92A 3HY7A 4ILWD 2OY2A 4AIGA 3U1RA 1CGEA 3B8ZA 4XM6A 1AYKA 1CAQA 2MZHA 5D2BA 3KWVC 2W14A 5CZMA 3AYUA 830CA 2DW0A 3P1VA 1UTZA 2W0DA 3KMEA 3L0VA 1C8TA 3KEKA 4JQGA 2MLRA 4WZVA 2CLTA 4IN9A 3B2ZA 1BKCI 4R3VA 5D1UA 4FU4A 1RM8A 2QPJA 1Y0VA 2XS3A 3G5CA 1JIZA 1UEAA 2X3CA 1BQOA 3HYGA 3VTGA 1I1IP 1JAQA 1ZTQA 3Q2HA 3ZXHA 2D1OA 2Y6DA 5B5PA 2OW1A 1CQRA 2O3EA 1G4KA 2WO9A 4FXQA 2J0TA 2JSDA 1HFCA 1JAPA 1AKLA 1QIAA 1MMPA 1I73A 1YP1A 3F15A 3LE9A 5I3MA 4HX3A 2OZRA 1FLSA 3LKAA 2WO8A 1PWVA 2X7MA 4DV8A 5H8XA 2DDFA 4PKQA 3LQBA 2OXWA 1K7GA 4WK7A 3KRYA 4GWNA 1BQQM 2V4BA 1JK3A 2Y6CA 4XCTA 3ZVSA 4AXQA 1CIZA 1DTHA 3EDHA 1IAEA 1SLMA 2KRJA 4Q1LA 1OM8A 1OM7A 1BIWA 2OXUA 1XFYA 1B8YA 1HTDA 5BOYA 5BPAA 2AYKA 4PKTA 4I03A 1BKCA 3O64A 5I43A 3KMCA 2E2DA 1K7IA 3LK8A 3DL1A 3LUNA 4PKVA 1GXDA 1SLNA 1S4BP 1ASTA 1A86A 4AYKA 3I7IA 1ZS0A 3LGPA 1SRPA 1HV5A 1C7KA 1OS9A 1A85A 2OW0A 1SMPA 5JMYA 3LMCA 2AIGP 1R1HA 3AIGA 1PWWA 3DPEA 4JP4A 1GO7P 1KUIA 1XFWA 3KEJA 1WNIA 2SRTA 1ZP5A 1ZXVA 3RTSA 3N2VA 2E3XA 4G0DA 2POJA 4H1QA 4I35A 3K7NA 1JANA 3E8RA 3HB2P 3MA2A 4JPAA 5BOTA 1HOVA 1FM1A 3LJGA 1JKYA 2TCLA 1H71P 3N2UA 3HY9A 1Y93A 2W13A 1R54A 2XS4A 5D1SA 1IAAA 1MMRA 3DNGA 4J4MA 2YIGA 1D7XA 5I12A 1IADA 5CXAA 5D7WA 2D1NA 1BUDA 3ZUKA 1KUHA 1DMTA 4HMAA 3TVCA 3USNA 2DDYA 3UVCA 2JIHA 2DW2A 3LIRA 2X3BA 3HBVP 2OW9A 1YCMA 4WF6A 3F17A 3EWJA 1CK7A 4XBHA 2W15A 1UMSA 2JT6A 4G9LA 4IUWA 1GKDA 1CGFA 1Y8JA 3V96B 3LJTA 1XFVA 2HU6A 1J7NA 2MZIA 1ROSA 1KUKA 3WV2A 3BA0A 3EHXA 3EDZA 2WOAA 1EAKA 4DF9A 1PWPA 4PKRA 1G12A 4WKEA 1QICA 1D8FA 1USNA 4L6TA 3L0TA 5I2ZA 4L63A 1SU3A 1R1IA 2OY4A 4ZR5A 4GWMA 2YB9A 3CKIA 1QIBA 1CGLA 3F16A 1IABA 2JT5A 1QJJA 3RTTA 4IJOA 1Q3AA 3NX7A 1HFSA 1K7QA 1C3IA 2FV5A 1QJIA 3F19A 3HBUP 1UMTA 4H84A 1XFUA 3G42A 4H30A 4XM7A 3LIKA 2OW2A 1IACA 3P24A 2K9CA 4PKUA 1G49A 5B5OA 1XFXA 2OVZA 3AYKA 1ATLA 2RJQA 4JA1A 1ZXCA 4GF1A 4DPEA 2ERPA 966CA 2K2GA 4GR8A 3EDGA 1UTTA 5D1TA 4H2EA 2A8HA 3DPFA 1BZSA 3OHLA 4H3XA 4L19A 1OS2A 3LUMA 4GUYA
chains in the Genus database with same CATH superfamily
3LILA 1Z3JA 4WKIA 4H49A 1AF0A 2I47A 2X3AA 1MMBA 3DWBA 3WV1A 1XURA 1BKCE 3LEAA 4ON1A 3TSKA 1JIWP 1G05A 1XUDA 4PKWA 3KECA 1RMZA 2L0RA 3HDBA 4EFSA 4L7AA 3F18A 1BUVM 3LQ0A 2OXZA 3GBOA 1OO9A 3TS4A 1FBLA 3O2XA 1YQYA 1KAPP 3K7LA 2MLSA 2EROA 1XAXA 5I4OA 1YOUA 3TT4A 2DW1A 1KUGA 2W12A 3SHIA 4DD8A 1L6JA 1TVIA 3VI1A 4XM8A 1XUCA 1OMJA 1BSWA 1G9KA 2OVXA 5CUHA 4CTHA 456CA 5I0LA 3WV3A 1JH1A 4FVLA 1GKCA 4JIJA 5LABA 2RJPA 4A7BA 2OI0A 5D3CA 1D8MA 1BM6A 4QKZA 3Q2GA 1D5JA 2MZEA 3F1AA 3LJZA 3I7GA 1OM6A 3ELMA 1R55A 1B3DA 1XFZA 3EDIA 1HY7A 1SATA 1O0QA 3KHIA 1GO8P 4H82A 3OHOA 2JNPA 1PWUA 1CXVA 3HDAP 1MMQA 2CKIA 1KUFA 4PKSA 1IAGA 4A3WA 3EHYA 1I76A 1PWQA 4GQLA 2O36A 1QUAA 1JAOA 5L7FA 2Z2DA 1ND1A 1GE6A 4FXYP 1GE5A 2ERQA 1JJ9A 1KBCA 1R1JA 2FV9A 4GR0A 2J83A 1GE7A 1ZVXA 1MNCA 2N8RA 2PJTA 4H76A 1O0TA 4AUOA 1EB6A 3DSLA 4GR3A 5L79A 1EUBA 2USNA 3B92A 3HY7A 4ILWD 2OY2A 1OZ9A 4AIGA 3U1RA 1CGEA 3B8ZA 4XM6A 1AYKA 1CAQA 2MZHA 5D2BA 3KWVC 2W14A 5CZMA 3AYUA 830CA 2DW0A 3P1VA 1UTZA 2W0DA 3KMEA 3L0VA 1C8TA 3KEKA 4JQGA 2MLRA 4WZVA 2CLTA 4IN9A 3B2ZA 1BKCI 4R3VA 5D1UA 4FU4A 1RM8A 2QPJA 1Y0VA 2XS3A 3G5CA 1JIZA 1UEAA 2X3CA 1BQOA 3HYGA 3VTGA 1I1IP 1JAQA 1ZTQA 3Q2HA 3ZXHA 2D1OA 2Y6DA 5B5PA 2OW1A 1CQRA 2O3EA 1G4KA 2WO9A 4FXQA 3DTKA 2J0TA 2JSDA 1HFCA 1JAPA 1AKLA 1QIAA 1MMPA 1I73A 1YP1A 3F15A 3LE9A 5I3MA 4HX3A 2OZRA 1FLSA 3LKAA 2WO8A 1PWVA 2X7MA 4DV8A 5H8XA 2DDFA 4PKQA 3LQBA 2OXWA 1K7GA 4WK7A 3KRYA 4GWNA 1BQQM 2V4BA 1JK3A 2Y6CA 4XCTA 3ZVSA 4AXQA 1CIZA 1DTHA 3EDHA 1IAEA 1SLMA 2KRJA 4Q1LA 1OM8A 1OM7A 1BIWA 2OXUA 1XFYA 1B8YA 1HTDA 5BOYA 5BPAA 2AYKA 4PKTA 4I03A 1BKCA 3O64A 1XM5A 5I43A 3KMCA 2E2DA 1K7IA 3LK8A 3DL1A 3LUNA 4PKVA 1GXDA 1SLNA 1S4BP 1ASTA 1A86A 4AYKA 3I7IA 1ZS0A 3LGPA 1SRPA 1HV5A 1C7KA 1OS9A 1A85A 2OW0A 1SMPA 5JMYA 3LMCA 2YUFA 2AIGP 1R1HA 3AIGA 1PWWA 3DPEA 4JP4A 1GO7P 1KUIA 1XFWA 3KEJA 1WNIA 2SRTA 1ZP5A 1ZXVA 3RTSA 3N2VA 2E3XA 4G0DA 2POJA 4H1QA 4I35A 3K7NA 1JANA 3E8RA 3HB2P 3MA2A 4JPAA 5BOTA 1HOVA 1FM1A 3LJGA 1JKYA 2TCLA 1H71P 3N2UA 3HY9A 1Y93A 2W13A 1R54A 2XS4A 5D1SA 1IAAA 1MMRA 3DNGA 4J4MA 2YIGA 1D7XA 5I12A 1IADA 5CXAA 5D7WA 2D1NA 1BUDA 3ZUKA 1KUHA 1DMTA 4HMAA 3TVCA 3USNA 2DDYA 3UVCA 2JIHA 2DW2A 3LIRA 2X3BA 3HBVP 2OW9A 1YCMA 4WF6A 3F17A 3EWJA 1CK7A 4XBHA 2W15A 1UMSA 2JT6A 4G9LA 4IUWA 1GKDA 1CGFA 1Y8JA 3V96B 3LJTA 1XFVA 2HU6A 1J7NA 2MZIA 1ROSA 1KUKA 3WV2A 3BA0A 3EHXA 3EDZA 3DTIA 2WOAA 1EAKA 4DF9A 1PWPA 4PKRA 1G12A 4WKEA 1QICA 1D8FA 1USNA 4L6TA 3L0TA 5I2ZA 4L63A 1SU3A 1R1IA 2OY4A 4ZR5A 4GWMA 2YB9A 3CKIA 1QIBA 1CGLA 3F16A 1IABA 2JT5A 1QJJA 3DTEA 3RTTA 4IJOA 1Q3AA 3NX7A 1HFSA 1K7QA 1C3IA 2FV5A 1QJIA 3F19A 3HBUP 1UMTA 4H84A 1XFUA 3G42A 4H30A 4XM7A 3LIKA 2OW2A 1IACA 3P24A 2K9CA 4PKUA 1G49A 5B5OA 1XFXA 2OVZA 3AYKA 1ATLA 2RJQA 4JA1A 1ZXCA 4GF1A 4DPEA 2ERPA 966CA 2K2GA 4GR8A 3EDGA 1UTTA 5D1TA 4H2EA 2A8HA 3DPFA 1BZSA 3OHLA 4H3XA 4L19A 1OS2A 3LUMA 4GUYA
chains in the Genus database with same CATH topology
3LILA 1Z3JA 4WKIA 4H49A 1AF0A 2I47A 2X3AA 1MMBA 3DWBA 3WV1A 1XURA 1BKCE 3LEAA 4ON1A 3TSKA 1JIWP 1G05A 1XUDA 4PKWA 3KECA 1RMZA 2L0RA 3HDBA 4EFSA 4L7AA 3F18A 1BUVM 3LQ0A 2OXZA 3GBOA 1OO9A 3TS4A 1FBLA 3O2XA 1YQYA 1KAPP 3K7LA 2MLSA 2EROA 5I4OA 1YOUA 3TT4A 2DW1A 1KUGA 2W12A 3SHIA 4DD8A 1L6JA 3VI1A 4XM8A 1XUCA 1OMJA 1BSWA 1G9KA 2OVXA 5CUHA 4CTHA 456CA 5I0LA 3WV3A 1JH1A 4FVLA 1GKCA 4JIJA 5LABA 2RJPA 4A7BA 2OI0A 5D3CA 1D8MA 1BM6A 4QKZA 3Q2GA 1D5JA 2MZEA 3LJZA 3F1AA 3I7GA 1OM6A 3ELMA 1R55A 1B3DA 1XFZA 3EDIA 1HY7A 1SATA 1O0QA 3KHIA 1GO8P 4H82A 3OHOA 2JNPA 1PWUA 1CXVA 3HDAP 1MMQA 2CKIA 1KUFA 4PKSA 1IAGA 4A3WA 3EHYA 1I76A 1PWQA 4GQLA 2O36A 1QUAA 1JAOA 5L7FA 2Z2DA 1ND1A 1GE6A 4FXYP 1GE5A 2ERQA 1JJ9A 1KBCA 1R1JA 2FV9A 4GR0A 2J83A 1GE7A 1ZVXA 1MNCA 2N8RA 2PJTA 4H76A 1O0TA 4AUOA 1EB6A 3DSLA 4GR3A 5L79A 1EUBA 2USNA 3B92A 3HY7A 4ILWD 2OY2A 4AIGA 3U1RA 1CGEA 3B8ZA 4XM6A 1AYKA 1CAQA 2MZHA 5D2BA 3KWVC 2W14A 5CZMA 3AYUA 830CA 2DW0A 3P1VA 1UTZA 2W0DA 3KMEA 3L0VA 1C8TA 3KEKA 4JQGA 2MLRA 4WZVA 2CLTA 4IN9A 3B2ZA 1BKCI 4R3VA 5D1UA 4FU4A 1RM8A 2QPJA 1Y0VA 2XS3A 3G5CA 1JIZA 1UEAA 2X3CA 1BQOA 3HYGA 3VTGA 1I1IP 1JAQA 1ZTQA 3Q2HA 3ZXHA 2D1OA 2Y6DA 5B5PA 2OW1A 1CQRA 2O3EA 1G4KA 2WO9A 4FXQA 3DTKA 2J0TA 2JSDA 1HFCA 1JAPA 1AKLA 1QIAA 1MMPA 1I73A 1YP1A 3F15A 3LE9A 5I3MA 4HX3A 2OZRA 1FLSA 3LKAA 2WO8A 1PWVA 2X7MA 4DV8A 5H8XA 2DDFA 4PKQA 3LQBA 2OXWA 1K7GA 4WK7A 3KRYA 4GWNA 1BQQM 2V4BA 1JK3A 2Y6CA 4XCTA 3ZVSA 4AXQA 1CIZA 1DTHA 3EDHA 1IAEA 1SLMA 2KRJA 4Q1LA 1OM8A 1OM7A 1BIWA 2OXUA 1XFYA 1B8YA 1HTDA 5BOYA 5BPAA 2AYKA 4PKTA 4I03A 1BKCA 3O64A 5I43A 3KMCA 2E2DA 1K7IA 3LK8A 3DL1A 3LUNA 4PKVA 1GXDA 1SLNA 1S4BP 1ASTA 1A86A 4AYKA 3I7IA 1ZS0A 3LGPA 1SRPA 1HV5A 1C7KA 1OS9A 1A85A 2OW0A 1SMPA 5JMYA 3LMCA 2YUFA 2AIGP 1R1HA 3AIGA 1PWWA 3DPEA 4JP4A 1GO7P 1KUIA 1XFWA 3KEJA 1WNIA 2SRTA 1ZP5A 1ZXVA 3RTSA 3N2VA 2E3XA 4G0DA 2POJA 4H1QA 4I35A 3K7NA 1JANA 3E8RA 3HB2P 3MA2A 4JPAA 5BOTA 1HOVA 1FM1A 3LJGA 1JKYA 2TCLA 1H71P 3N2UA 3HY9A 1Y93A 2W13A 1R54A 2XS4A 5D1SA 1IAAA 1MMRA 3DNGA 4J4MA 2YIGA 1D7XA 5I12A 1IADA 5CXAA 5D7WA 2D1NA 1BUDA 3ZUKA 1KUHA 1DMTA 4HMAA 3TVCA 3USNA 2DDYA 3UVCA 2JIHA 2DW2A 3LIRA 2X3BA 3HBVP 2OW9A 1YCMA 4WF6A 3F17A 3EWJA 1CK7A 4XBHA 2W15A 1UMSA 2JT6A 4G9LA 4IUWA 1GKDA 1CGFA 1Y8JA 3V96B 3LJTA 1XFVA 2HU6A 1J7NA 2MZIA 1ROSA 1KUKA 3WV2A 3BA0A 3EHXA 3EDZA 3DTIA 2WOAA 1EAKA 4DF9A 1PWPA 4PKRA 1G12A 4WKEA 1QICA 1D8FA 1USNA 4L6TA 3L0TA 5I2ZA 4L63A 1SU3A 1R1IA 2OY4A 4ZR5A 4GWMA 2YB9A 3CKIA 1QIBA 1CGLA 3F16A 1IABA 2JT5A 1QJJA 3DTEA 3RTTA 4IJOA 1Q3AA 3NX7A 1HFSA 1K7QA 1C3IA 2FV5A 1QJIA 3F19A 3HBUP 1UMTA 4H84A 1XFUA 3G42A 4H30A 4XM7A 3LIKA 2OW2A 1IACA 3P24A 2K9CA 4PKUA 1G49A 5B5OA 1XFXA 2OVZA 3AYKA 1ATLA 2RJQA 4JA1A 1ZXCA 4GF1A 4DPEA 2ERPA 966CA 2K2GA 4GR8A 3EDGA 1UTTA 5D1TA 4H2EA 2A8HA 3DPFA 1BZSA 3OHLA 4H3XA 4L19A 1OS2A 3LUMA 4GUYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LIL A;  1Z3J A;  4WKI A;  4H49 A;  1AF0 A;  2I47 A;  2X3A A;  1MMB A;  3DWB A;  3WV1 A;  1XUR A;  1BKC E;  3LEA A;  4ON1 A;  3TSK A;  1JIW P;  1G05 A;  1XUD A;  4PKW A;  3KEC A;  1RMZ A;  2L0R A;  3HDB A;  4EFS A;  3F18 A;  1BUV M;  3LQ0 A;  2OXZ A;  3GBO A;  1OO9 A;  3TS4 A;  1FBL A;  3O2X A;  1YQY A;  1KAP P;  3K7L A;  2MLS A;  2ERO A;  5I4O A;  1YOU A;  3TT4 A;  2DW1 A;  1KUG A;  2W12 A;  3SHI A;  4DD8 A;  1L6J A;  3VI1 A;  4XM8 A;  1XUC A;  1OMJ A;  1BSW A;  1G9K A;  2OVX A;  5CUH A;  4CTH A;  456C A;  5I0L A;  3WV3 A;  1JH1 A;  4FVL A;  1GKC A;  4JIJ A;  5LAB A;  2RJP A;  4A7B A;  2OI0 A;  5D3C A;  1D8M A;  1BM6 A;  4QKZ A;  3Q2G A;  1D5J A;  2MZE A;  3LJZ A;  3F1A A;  3I7G A;  1OM6 A;  3ELM A;  1R55 A;  1B3D A;  1XFZ A;  3EDI A;  1HY7 A;  1SAT A;  1O0Q A;  3KHI A;  1GO8 P;  4H82 A;  3OHO A;  2JNP A;  1PWU A;  1CXV A;  3HDA P;  1MMQ A;  2CKI A;  1KUF A;  4PKS A;  1IAG A;  4A3W A;  3EHY A;  1I76 A;  1PWQ A;  4GQL A;  2O36 A;  1QUA A;  1JAO A;  5L7F A;  2Z2D A;  1ND1 A;  1GE6 A;  4FXY P;  1GE5 A;  2ERQ A;  1JJ9 A;  1KBC A;  1R1J A;  2FV9 A;  4GR0 A;  2J83 A;  1GE7 A;  1ZVX A;  1MNC A;  2N8R A;  2PJT A;  4H76 A;  1O0T A;  4AUO A;  1EB6 A;  3DSL A;  4GR3 A;  5L79 A;  1EUB A;  2USN A;  3B92 A;  3HY7 A;  4ILW D;  2OY2 A;  4AIG A;  3U1R A;  1CGE A;  3B8Z A;  4XM6 A;  1AYK A;  1CAQ A;  2MZH A;  5D2B A;  3KWV C;  2W14 A;  5CZM A;  3AYU A;  830C A;  2DW0 A;  3P1V A;  1UTZ A;  2W0D A;  3KME A;  3L0V A;  1C8T A;  3KEK A;  4JQG A;  2MLR A;  4WZV A;  2CLT A;  4IN9 A;  3B2Z A;  1BKC I;  4R3V A;  5D1U A;  4FU4 A;  1RM8 A;  2QPJ A;  1Y0V A;  2XS3 A;  3G5C A;  1JIZ A;  1UEA A;  2X3C A;  1BQO A;  3HYG A;  3VTG A;  1I1I P;  1JAQ A;  1ZTQ A;  3Q2H A;  3ZXH A;  2D1O A;  2Y6D A;  5B5P A;  2OW1 A;  1CQR A;  2O3E A;  1G4K A;  2WO9 A;  4FXQ A;  2J0T A;  2JSD A;  1HFC A;  1JAP A;  1AKL A;  1QIA A;  1MMP A;  1I73 A;  1YP1 A;  3F15 A;  3LE9 A;  5I3M A;  4HX3 A;  2OZR A;  1FLS A;  3LKA A;  2WO8 A;  1PWV A;  2X7M A;  4DV8 A;  5H8X A;  2DDF A;  4PKQ A;  3LQB A;  2OXW A;  1K7G A;  4WK7 A;  3KRY A;  4GWN A;  1BQQ M;  2V4B A;  1JK3 A;  2Y6C A;  4XCT A;  3ZVS A;  4AXQ A;  1CIZ A;  1DTH A;  3EDH A;  1IAE A;  1SLM A;  2KRJ A;  4Q1L A;  1OM8 A;  1OM7 A;  1BIW A;  2OXU A;  1XFY A;  1B8Y A;  1HTD A;  5BOY A;  5BPA A;  2AYK A;  4PKT A;  4I03 A;  1BKC A;  3O64 A;  5I43 A;  3KMC A;  2E2D A;  1K7I A;  3LK8 A;  3DL1 A;  3LUN A;  4PKV A;  1GXD A;  1SLN A;  1S4B P;  1AST A;  1A86 A;  4AYK A;  3I7I A;  1ZS0 A;  3LGP A;  1SRP A;  1HV5 A;  1C7K A;  1OS9 A;  1A85 A;  2OW0 A;  1SMP A;  5JMY A;  3LMC A;  2AIG P;  1R1H A;  3AIG A;  1PWW A;  3DPE A;  4JP4 A;  1GO7 P;  1KUI A;  1XFW A;  3KEJ A;  1WNI A;  2SRT A;  1ZP5 A;  1ZXV A;  3RTS A;  3N2V A;  2E3X A;  4G0D A;  2POJ A;  4H1Q A;  4I35 A;  3K7N A;  1JAN A;  3E8R A;  3HB2 P;  3MA2 A;  4JPA A;  5BOT A;  1HOV A;  1FM1 A;  3LJG A;  1JKY A;  2TCL A;  1H71 P;  3N2U A;  3HY9 A;  1Y93 A;  2W13 A;  1R54 A;  2XS4 A;  5D1S A;  1IAA A;  1MMR A;  3DNG A;  4J4M A;  2YIG A;  1D7X A;  5I12 A;  1IAD A;  5CXA A;  5D7W A;  2D1N A;  1BUD A;  3ZUK A;  1KUH A;  1DMT A;  4HMA A;  3TVC A;  3USN A;  2DDY A;  3UVC A;  2JIH A;  2DW2 A;  3LIR A;  2X3B A;  3HBV P;  2OW9 A;  1YCM A;  4WF6 A;  3F17 A;  3EWJ A;  1CK7 A;  4XBH A;  2W15 A;  1UMS A;  2JT6 A;  4G9L A;  4IUW A;  1GKD A;  1CGF A;  1Y8J A;  3V96 B;  3LJT A;  1XFV A;  2HU6 A;  1J7N A;  2MZI A;  1ROS A;  1KUK A;  3WV2 A;  3BA0 A;  3EHX A;  3EDZ A;  2WOA A;  1EAK A;  4DF9 A;  1PWP A;  4PKR A;  1G12 A;  4WKE A;  1QIC A;  1D8F A;  1USN A;  4L6T A;  3L0T A;  5I2Z A;  4L63 A;  1SU3 A;  1R1I A;  2OY4 A;  4ZR5 A;  4GWM A;  2YB9 A;  3CKI A;  1QIB A;  1CGL A;  3F16 A;  1IAB A;  2JT5 A;  1QJJ A;  3RTT A;  4IJO A;  1Q3A A;  3NX7 A;  1HFS A;  1K7Q A;  1C3I A;  2FV5 A;  1QJI A;  3F19 A;  3HBU P;  1UMT A;  4H84 A;  1XFU A;  3G42 A;  4H30 A;  4XM7 A;  3LIK A;  2OW2 A;  1IAC A;  3P24 A;  2K9C A;  4PKU A;  1G49 A;  5B5O A;  1XFX A;  2OVZ A;  3AYK A;  1ATL A;  2RJQ A;  4JA1 A;  1ZXC A;  4GF1 A;  4DPE A;  2ERP A;  966C A;  2K2G A;  4GR8 A;  3EDG A;  1UTT A;  5D1T A;  4H2E A;  2A8H A;  3DPF A;  1BZS A;  3OHL A;  4H3X A;  4L19 A;  1OS2 A;  3LUM A;  4GUY A; 
#chains in the Genus database with same CATH topology
 3LIL A;  1Z3J A;  4WKI A;  4H49 A;  1AF0 A;  2I47 A;  2X3A A;  1MMB A;  3DWB A;  3WV1 A;  1XUR A;  1BKC E;  3LEA A;  4ON1 A;  3TSK A;  1JIW P;  1G05 A;  1XUD A;  4PKW A;  3KEC A;  1RMZ A;  2L0R A;  3HDB A;  4EFS A;  4L7A A;  3F18 A;  1BUV M;  3LQ0 A;  2OXZ A;  3GBO A;  1OO9 A;  3TS4 A;  1FBL A;  3O2X A;  1YQY A;  1KAP P;  3K7L A;  2MLS A;  2ERO A;  1XAX A;  5I4O A;  1YOU A;  3TT4 A;  2DW1 A;  1KUG A;  2W12 A;  3SHI A;  4DD8 A;  1L6J A;  1TVI A;  3VI1 A;  4XM8 A;  1XUC A;  1OMJ A;  1BSW A;  1G9K A;  2OVX A;  5CUH A;  4CTH A;  456C A;  5I0L A;  3WV3 A;  1JH1 A;  4FVL A;  1GKC A;  4JIJ A;  5LAB A;  2RJP A;  4A7B A;  2OI0 A;  5D3C A;  1D8M A;  1BM6 A;  4QKZ A;  3Q2G A;  1D5J A;  2MZE A;  3F1A A;  3LJZ A;  3I7G A;  1OM6 A;  3ELM A;  1R55 A;  1B3D A;  1XFZ A;  3EDI A;  1HY7 A;  1SAT A;  1O0Q A;  3KHI A;  1GO8 P;  4H82 A;  3OHO A;  2JNP A;  1PWU A;  1CXV A;  3HDA P;  1MMQ A;  2CKI A;  1KUF A;  4PKS A;  1IAG A;  4A3W A;  3EHY A;  1I76 A;  1PWQ A;  4GQL A;  2O36 A;  1QUA A;  1JAO A;  5L7F A;  2Z2D A;  1ND1 A;  1GE6 A;  4FXY P;  1GE5 A;  2ERQ A;  1JJ9 A;  1KBC A;  1R1J A;  2FV9 A;  4GR0 A;  2J83 A;  1GE7 A;  1ZVX A;  1MNC A;  2N8R A;  2PJT A;  4H76 A;  1O0T A;  4AUO A;  1EB6 A;  3DSL A;  4GR3 A;  5L79 A;  1EUB A;  2USN A;  3B92 A;  3HY7 A;  4ILW D;  2OY2 A;  1OZ9 A;  4AIG A;  3U1R A;  1CGE A;  3B8Z A;  4XM6 A;  1AYK A;  1CAQ A;  2MZH A;  5D2B A;  3KWV C;  2W14 A;  5CZM A;  3AYU A;  830C A;  2DW0 A;  3P1V A;  1UTZ A;  2W0D A;  3KME A;  3L0V A;  1C8T A;  3KEK A;  4JQG A;  2MLR A;  4WZV A;  2CLT A;  4IN9 A;  3B2Z A;  1BKC I;  4R3V A;  5D1U A;  4FU4 A;  1RM8 A;  2QPJ A;  1Y0V A;  2XS3 A;  3G5C A;  1JIZ A;  1UEA A;  2X3C A;  1BQO A;  3HYG A;  3VTG A;  1I1I P;  1JAQ A;  1ZTQ A;  3Q2H A;  3ZXH A;  2D1O A;  2Y6D A;  5B5P A;  2OW1 A;  1CQR A;  2O3E A;  1G4K A;  2WO9 A;  4FXQ A;  3DTK A;  2J0T A;  2JSD A;  1HFC A;  1JAP A;  1AKL A;  1QIA A;  1MMP A;  1I73 A;  1YP1 A;  3F15 A;  3LE9 A;  5I3M A;  4HX3 A;  2OZR A;  1FLS A;  3LKA A;  2WO8 A;  1PWV A;  2X7M A;  4DV8 A;  5H8X A;  2DDF A;  4PKQ A;  3LQB A;  2OXW A;  1K7G A;  4WK7 A;  3KRY A;  4GWN A;  1BQQ M;  2V4B A;  1JK3 A;  2Y6C A;  4XCT A;  3ZVS A;  4AXQ A;  1CIZ A;  1DTH A;  3EDH A;  1IAE A;  1SLM A;  2KRJ A;  4Q1L A;  1OM8 A;  1OM7 A;  1BIW A;  2OXU A;  1XFY A;  1B8Y A;  1HTD A;  5BOY A;  5BPA A;  2AYK A;  4PKT A;  4I03 A;  1BKC A;  3O64 A;  1XM5 A;  5I43 A;  3KMC A;  2E2D A;  1K7I A;  3LK8 A;  3DL1 A;  3LUN A;  4PKV A;  1GXD A;  1SLN A;  1S4B P;  1AST A;  1A86 A;  4AYK A;  3I7I A;  1ZS0 A;  3LGP A;  1SRP A;  1HV5 A;  1C7K A;  1OS9 A;  1A85 A;  2OW0 A;  1SMP A;  5JMY A;  3LMC A;  2YUF A;  2AIG P;  1R1H A;  3AIG A;  1PWW A;  3DPE A;  4JP4 A;  1GO7 P;  1KUI A;  1XFW A;  3KEJ A;  1WNI A;  2SRT A;  1ZP5 A;  1ZXV A;  3RTS A;  3N2V A;  2E3X A;  4G0D A;  2POJ A;  4H1Q A;  4I35 A;  3K7N A;  1JAN A;  3E8R A;  3HB2 P;  3MA2 A;  4JPA A;  5BOT A;  1HOV A;  1FM1 A;  3LJG A;  1JKY A;  2TCL A;  1H71 P;  3N2U A;  3HY9 A;  1Y93 A;  2W13 A;  1R54 A;  2XS4 A;  5D1S A;  1IAA A;  1MMR A;  3DNG A;  4J4M A;  2YIG A;  1D7X A;  5I12 A;  1IAD A;  5CXA A;  5D7W A;  2D1N A;  1BUD A;  3ZUK A;  1KUH A;  1DMT A;  4HMA A;  3TVC A;  3USN A;  2DDY A;  3UVC A;  2JIH A;  2DW2 A;  3LIR A;  2X3B A;  3HBV P;  2OW9 A;  1YCM A;  4WF6 A;  3F17 A;  3EWJ A;  1CK7 A;  4XBH A;  2W15 A;  1UMS A;  2JT6 A;  4G9L A;  4IUW A;  1GKD A;  1CGF A;  1Y8J A;  3V96 B;  3LJT A;  1XFV A;  2HU6 A;  1J7N A;  2MZI A;  1ROS A;  1KUK A;  3WV2 A;  3BA0 A;  3EHX A;  3EDZ A;  3DTI A;  2WOA A;  1EAK A;  4DF9 A;  1PWP A;  4PKR A;  1G12 A;  4WKE A;  1QIC A;  1D8F A;  1USN A;  4L6T A;  3L0T A;  5I2Z A;  4L63 A;  1SU3 A;  1R1I A;  2OY4 A;  4ZR5 A;  4GWM A;  2YB9 A;  3CKI A;  1QIB A;  1CGL A;  3F16 A;  1IAB A;  2JT5 A;  1QJJ A;  3DTE A;  3RTT A;  4IJO A;  1Q3A A;  3NX7 A;  1HFS A;  1K7Q A;  1C3I A;  2FV5 A;  1QJI A;  3F19 A;  3HBU P;  1UMT A;  4H84 A;  1XFU A;  3G42 A;  4H30 A;  4XM7 A;  3LIK A;  2OW2 A;  1IAC A;  3P24 A;  2K9C A;  4PKU A;  1G49 A;  5B5O A;  1XFX A;  2OVZ A;  3AYK A;  1ATL A;  2RJQ A;  4JA1 A;  1ZXC A;  4GF1 A;  4DPE A;  2ERP A;  966C A;  2K2G A;  4GR8 A;  3EDG A;  1UTT A;  5D1T A;  4H2E A;  2A8H A;  3DPF A;  1BZS A;  3OHL A;  4H3X A;  4L19 A;  1OS2 A;  3LUM A;  4GUY A; 
#chains in the Genus database with same CATH homology
 3LIL A;  1Z3J A;  4WKI A;  4H49 A;  1AF0 A;  2I47 A;  2X3A A;  1MMB A;  3DWB A;  3WV1 A;  1XUR A;  1BKC E;  3LEA A;  4ON1 A;  3TSK A;  1JIW P;  1G05 A;  1XUD A;  4PKW A;  3KEC A;  1RMZ A;  2L0R A;  3HDB A;  4EFS A;  4L7A A;  3F18 A;  1BUV M;  3LQ0 A;  2OXZ A;  3GBO A;  1OO9 A;  3TS4 A;  1FBL A;  3O2X A;  1YQY A;  1KAP P;  3K7L A;  2MLS A;  2ERO A;  5I4O A;  1YOU A;  3TT4 A;  2DW1 A;  1KUG A;  2W12 A;  3SHI A;  4DD8 A;  1L6J A;  3VI1 A;  4XM8 A;  1XUC A;  1OMJ A;  1BSW A;  1G9K A;  2OVX A;  5CUH A;  4CTH A;  456C A;  5I0L A;  3WV3 A;  1JH1 A;  4FVL A;  1GKC A;  4JIJ A;  5LAB A;  2RJP A;  4A7B A;  2OI0 A;  5D3C A;  1D8M A;  1BM6 A;  4QKZ A;  3Q2G A;  1D5J A;  2MZE A;  3LJZ A;  3F1A A;  3I7G A;  1OM6 A;  3ELM A;  1R55 A;  1B3D A;  1XFZ A;  3EDI A;  1HY7 A;  1SAT A;  1O0Q A;  3KHI A;  1GO8 P;  4H82 A;  3OHO A;  2JNP A;  1PWU A;  1CXV A;  3HDA P;  1MMQ A;  2CKI A;  1KUF A;  4PKS A;  1IAG A;  4A3W A;  3EHY A;  1I76 A;  1PWQ A;  4GQL A;  2O36 A;  1QUA A;  1JAO A;  5L7F A;  2Z2D A;  1ND1 A;  1GE6 A;  4FXY P;  1GE5 A;  2ERQ A;  1JJ9 A;  1KBC A;  1R1J A;  2FV9 A;  4GR0 A;  2J83 A;  1GE7 A;  1ZVX A;  1MNC A;  2N8R A;  2PJT A;  4H76 A;  1O0T A;  4AUO A;  1EB6 A;  3DSL A;  4GR3 A;  5L79 A;  1EUB A;  2USN A;  3B92 A;  3HY7 A;  4ILW D;  2OY2 A;  4AIG A;  3U1R A;  1CGE A;  3B8Z A;  4XM6 A;  1AYK A;  1CAQ A;  2MZH A;  5D2B A;  3KWV C;  2W14 A;  5CZM A;  3AYU A;  830C A;  2DW0 A;  3P1V A;  1UTZ A;  2W0D A;  3KME A;  3L0V A;  1C8T A;  3KEK A;  4JQG A;  2MLR A;  4WZV A;  2CLT A;  4IN9 A;  3B2Z A;  1BKC I;  4R3V A;  5D1U A;  4FU4 A;  1RM8 A;  2QPJ A;  1Y0V A;  2XS3 A;  3G5C A;  1JIZ A;  1UEA A;  2X3C A;  1BQO A;  3HYG A;  3VTG A;  1I1I P;  1JAQ A;  1ZTQ A;  3Q2H A;  3ZXH A;  2D1O A;  2Y6D A;  5B5P A;  2OW1 A;  1CQR A;  2O3E A;  1G4K A;  2WO9 A;  4FXQ A;  3DTK A;  2J0T A;  2JSD A;  1HFC A;  1JAP A;  1AKL A;  1QIA A;  1MMP A;  1I73 A;  1YP1 A;  3F15 A;  3LE9 A;  5I3M A;  4HX3 A;  2OZR A;  1FLS A;  3LKA A;  2WO8 A;  1PWV A;  2X7M A;  4DV8 A;  5H8X A;  2DDF A;  4PKQ A;  3LQB A;  2OXW A;  1K7G A;  4WK7 A;  3KRY A;  4GWN A;  1BQQ M;  2V4B A;  1JK3 A;  2Y6C A;  4XCT A;  3ZVS A;  4AXQ A;  1CIZ A;  1DTH A;  3EDH A;  1IAE A;  1SLM A;  2KRJ A;  4Q1L A;  1OM8 A;  1OM7 A;  1BIW A;  2OXU A;  1XFY A;  1B8Y A;  1HTD A;  5BOY A;  5BPA A;  2AYK A;  4PKT A;  4I03 A;  1BKC A;  3O64 A;  5I43 A;  3KMC A;  2E2D A;  1K7I A;  3LK8 A;  3DL1 A;  3LUN A;  4PKV A;  1GXD A;  1SLN A;  1S4B P;  1AST A;  1A86 A;  4AYK A;  3I7I A;  1ZS0 A;  3LGP A;  1SRP A;  1HV5 A;  1C7K A;  1OS9 A;  1A85 A;  2OW0 A;  1SMP A;  5JMY A;  3LMC A;  2YUF A;  2AIG P;  1R1H A;  3AIG A;  1PWW A;  3DPE A;  4JP4 A;  1GO7 P;  1KUI A;  1XFW A;  3KEJ A;  1WNI A;  2SRT A;  1ZP5 A;  1ZXV A;  3RTS A;  3N2V A;  2E3X A;  4G0D A;  2POJ A;  4H1Q A;  4I35 A;  3K7N A;  1JAN A;  3E8R A;  3HB2 P;  3MA2 A;  4JPA A;  5BOT A;  1HOV A;  1FM1 A;  3LJG A;  1JKY A;  2TCL A;  1H71 P;  3N2U A;  3HY9 A;  1Y93 A;  2W13 A;  1R54 A;  2XS4 A;  5D1S A;  1IAA A;  1MMR A;  3DNG A;  4J4M A;  2YIG A;  1D7X A;  5I12 A;  1IAD A;  5CXA A;  5D7W A;  2D1N A;  1BUD A;  3ZUK A;  1KUH A;  1DMT A;  4HMA A;  3TVC A;  3USN A;  2DDY A;  3UVC A;  2JIH A;  2DW2 A;  3LIR A;  2X3B A;  3HBV P;  2OW9 A;  1YCM A;  4WF6 A;  3F17 A;  3EWJ A;  1CK7 A;  4XBH A;  2W15 A;  1UMS A;  2JT6 A;  4G9L A;  4IUW A;  1GKD A;  1CGF A;  1Y8J A;  3V96 B;  3LJT A;  1XFV A;  2HU6 A;  1J7N A;  2MZI A;  1ROS A;  1KUK A;  3WV2 A;  3BA0 A;  3EHX A;  3EDZ A;  3DTI A;  2WOA A;  1EAK A;  4DF9 A;  1PWP A;  4PKR A;  1G12 A;  4WKE A;  1QIC A;  1D8F A;  1USN A;  4L6T A;  3L0T A;  5I2Z A;  4L63 A;  1SU3 A;  1R1I A;  2OY4 A;  4ZR5 A;  4GWM A;  2YB9 A;  3CKI A;  1QIB A;  1CGL A;  3F16 A;  1IAB A;  2JT5 A;  1QJJ A;  3DTE A;  3RTT A;  4IJO A;  1Q3A A;  3NX7 A;  1HFS A;  1K7Q A;  1C3I A;  2FV5 A;  1QJI A;  3F19 A;  3HBU P;  1UMT A;  4H84 A;  1XFU A;  3G42 A;  4H30 A;  4XM7 A;  3LIK A;  2OW2 A;  1IAC A;  3P24 A;  2K9C A;  4PKU A;  1G49 A;  5B5O A;  1XFX A;  2OVZ A;  3AYK A;  1ATL A;  2RJQ A;  4JA1 A;  1ZXC A;  4GF1 A;  4DPE A;  2ERP A;  966C A;  2K2G A;  4GR8 A;  3EDG A;  1UTT A;  5D1T A;  4H2E A;  2A8H A;  3DPF A;  1BZS A;  3OHL A;  4H3X A;  4L19 A;  1OS2 A;  3LUM A;  4GUY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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