2JT5A

Solution structure of matrix metalloproteinase 3 (mmp-3) in the presence of n-hydroxy-2-[n-(2-hydroxyethyl)biphenyl-4-sulfonamide] hydroxamic acid (mlc88)
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
161
structure length
161
Chain Sequence
GIPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLYHSLTDLTRFRLSQDDINGIQSLYGP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Matrix metalloproteinase-inhibitor interaction: the solution structure of the catalytic domain of human matrix metalloproteinase-3 with different inhibitors
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Stromelysin-1
total genus 42
structure length 161
sequence length 161
ec nomenclature ec 3.4.24.17: Stromelysin 1.
pdb deposition date 2007-07-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 2jt5A00
3TS4A 1JK3A 3V96B 4Q1LA 3LE9A 2MLSA 1SU3A 3B92A 3CKIA 3HB2P 3Q2GA 2J0TA 1BIWA 1ZXCA 1XURA 1FBLA 1R55A 3EDZA 2OXUA 3NX7A 5I4OA 1G9KA 5B5OA 4XM6A 5JMYA 1ZS0A 4CTHA 4EFSA 4ZR5A 4FU4A 1OS2A 4I35A 3KWVC 3EDHA 1PWPA 1UMSA 1HFSA 1RM8A 1R54A 1Y93A 2X3AA 1QICA 2DDYA 2QPJA 2EROA 3HDBA 2DW1A 4H30A 4PKRA 2JT5A 1I1IP 4XM7A 3MA2A 1K7IA 1HOVA 3HY7A 2A8HA 1I73A 1XFZA 2JT6A 3DPFA 2W0DA 4GR8A 1DTHA 1GKCA 1I76A 1BQOA 1K7GA 2DW2A 3DSLA 1BUVM 3O64A 1L6JA 1GE7A 3RTTA 1BUDA 4QKZA 1IAAA 1YQYA 1PWVA 1C7KA 2XS4A 3KEJA 3ELMA 5D2BA 2Y6DA 1BKCE 4PKVA 4IJOA 3LGPA 1GO7P 2SRTA 1GKDA 1CIZA 5D1SA 1PWWA 2CKIA 3E8RA 2CLTA 2MZIA 3LUMA 1AKLA 3DL1A 3LUNA 3TVCA 2OW9A 1J7NA 2AIGP 3KHIA 2W15A 1KUKA 1XFXA 4H76A 3P1VA 3L0VA 4AYKA 1HFCA 1CGLA 4WK7A 1KUGA 1JAPA 4GR0A 1BKCI 1HTDA 1BZSA 4WKEA 2O36A 1HV5A 1R1JA 1UEAA 3WV1A 1CQRA 3HBVP 3O2XA 1XFUA 3LMCA 1XFVA 1AF0A 3LEAA 2JSDA 3OHLA 1XUDA 1UMTA 5BPAA 4PKUA 2I47A 3OHOA 2OI0A 5CUHA 4I03A 3WV2A 2TCLA 1JIWP 966CA 2MZHA 1GO8P 5CZMA 3ZVSA 5I12A 1BQQM 4JQGA 1H71P 4GWMA 1EB6A 3F17A 3SHIA 2PJTA 2J83A 2OXWA 2W14A 1OM7A 1OMJA 3HDAP 4XBHA 1XFWA 1Z3JA 1UTZA 2D1OA 1KAPP 3HBUP 4HMAA 2DDFA 3F1AA 5I43A 4AXQA 4G0DA 1GE6A 1JAOA 3UVCA 1JIZA 4J4MA 4GR3A 3G5CA 5BOTA 1A86A 4PKSA 4DF9A 4AUOA 4ILWD 4PKQA 5L79A 1SRPA 4L19A 2OVZA 1RMZA 2ERPA 4L6TA 3B2ZA 4DPEA 1MMQA 1SATA 2OW2A 1YP1A 1OS9A 5CXAA 3EHXA 1IAEA 1FLSA 1CGFA 2MZEA 4XCTA 3F15A 3EDGA 1CAQA 1QIBA 4WKIA 2K9CA 2E2DA 1QJIA 2KRJA 2AYKA 2OW1A 1C3IA 3KMCA 4R3VA 1AYKA 2XS3A 3AYUA 3EHYA 1O0QA 4JP4A 1BSWA 4H82A 5D1UA 2RJQA 3KECA 4FVLA 1JANA 3ZUKA 3LK8A 2POJA 5L7FA 3F19A 1JJ9A 3F18A 5D3CA 5H8XA 1JKYA 3EWJA 1BM6A 3LJGA 3BA0A 1A85A 5LABA 3AYKA 5I2ZA 1KUIA 3N2UA 4ON1A 4PKTA 1B3DA 1KUHA 2W13A 5B5PA 1GE5A 3DPEA 1K7QA 1OM6A 4JIJA 1WNIA 4L63A 1IACA 2X3BA 3K7NA 3DWBA 3EDIA 1USNA 4H1QA 1ASTA 4GF1A 3KEKA 1MMRA 2D1NA 1G12A 4AIGA 4IN9A 1MMPA 1G49A 3VTGA 2YB9A 2OXZA 2FV5A 3DNGA 3GBOA 3HYGA 3Q2HA 3LIRA 2X7MA 3G42A 1CXVA 1MNCA 1QJJA 3LJZA 1CK7A 3AIGA 4GWNA 4H3XA 3I7GA 3KRYA 1O0TA 1SLNA 1ZTQA 4WZVA 1D8MA 1R1IA 2FV9A 4GQLA 2MLRA 2RJPA 1XUCA 2Y6CA 4A3WA 1BKCA 1DMTA 2OW0A 4H49A 2OZRA 1ROSA 1IADA 3LQ0A 1IAGA 2JIHA 1R1HA 3B8ZA 1MMBA 1G4KA 1UTTA 1XFYA 1OO9A 4G9LA 4H84A 1KUFA 2USNA 3LJTA 3P24A 1D8FA 4XM8A 3WV3A 3LIKA 2OY2A 2WO8A 1S4BP 1JAQA 1GXDA 3LKAA 5I0LA 1Y8JA 3LILA 3RTSA 5BOYA 1JH1A 1Y0VA 3I7IA 3HY9A 1ND1A 1PWQA 1YCMA 2K2GA 3TT4A 1HY7A 4JA1A 1QUAA 2DW0A 4DV8A 1SMPA 2JNPA 1EUBA 2ERQA 1ZXVA 5D7WA 5D1TA 1B8YA 4PKWA 1EAKA 2L0RA 1YOUA 1D7XA 3K7LA 3ZXHA 4FXQA 4DD8A 3VI1A 2Z2DA 1G05A 2YIGA 3TSKA 4FXYP 1QIAA 1CGEA 1PWUA 1SLMA 3USNA 4H2EA 2X3CA 2OY4A 2V4BA 4GUYA 1IABA 1OM8A 4IUWA 4A7BA 3N2VA 1C8TA 4HX3A 2O3EA 1ZP5A 456CA 1D5JA 3L0TA 1KBCA 2WOAA 3LQBA 2HU6A 3KMEA 830CA 2WO9A 3U1RA 4JPAA 2OVXA 4WF6A 1Q3AA 1ATLA 1ZVXA 1FM1A 5I3MA 2W12A 3F16A 2E3XA 2N8RA
chains in the Genus database with same CATH superfamily
3TS4A 1JK3A 3V96B 4Q1LA 3LE9A 2MLSA 1SU3A 3B92A 3CKIA 3HB2P 3Q2GA 2J0TA 1BIWA 1ZXCA 1XURA 1FBLA 1R55A 3EDZA 2OXUA 3NX7A 5I4OA 1G9KA 5B5OA 4XM6A 5JMYA 1ZS0A 4CTHA 4EFSA 4ZR5A 4FU4A 1OS2A 4I35A 3KWVC 3EDHA 1PWPA 1UMSA 1HFSA 1RM8A 1R54A 1Y93A 2X3AA 1QICA 2DDYA 1OZ9A 2QPJA 2EROA 3HDBA 2DW1A 4H30A 4PKRA 2JT5A 1I1IP 4XM7A 3MA2A 1K7IA 1HOVA 3HY7A 2A8HA 1I73A 1XFZA 2JT6A 3DPFA 2W0DA 4GR8A 1DTHA 1GKCA 1I76A 1BQOA 1K7GA 2DW2A 3DSLA 1BUVM 3O64A 1L6JA 1GE7A 3RTTA 1BUDA 4QKZA 1IAAA 1YQYA 1PWVA 1C7KA 2XS4A 3KEJA 3ELMA 5D2BA 2Y6DA 1BKCE 4PKVA 4IJOA 3LGPA 1GO7P 2SRTA 1GKDA 1CIZA 5D1SA 1PWWA 2CKIA 3E8RA 2CLTA 2MZIA 3LUMA 1AKLA 3DL1A 3LUNA 3TVCA 2OW9A 4L7AA 1J7NA 2AIGP 3KHIA 2W15A 1KUKA 1XFXA 4H76A 3P1VA 3L0VA 4AYKA 1HFCA 1CGLA 4WK7A 1KUGA 1JAPA 4GR0A 1BKCI 1HTDA 1BZSA 4WKEA 2O36A 1HV5A 1R1JA 1UEAA 3WV1A 1CQRA 3HBVP 3O2XA 1XM5A 2YUFA 1XFUA 3DTIA 3LMCA 1XFVA 1AF0A 3LEAA 2JSDA 3OHLA 1XUDA 1UMTA 5BPAA 4PKUA 2I47A 3OHOA 2OI0A 5CUHA 4I03A 3WV2A 2TCLA 1JIWP 966CA 2MZHA 1GO8P 5CZMA 3ZVSA 5I12A 1BQQM 4JQGA 1H71P 4GWMA 1EB6A 3F17A 3SHIA 2PJTA 2J83A 2OXWA 2W14A 1OM7A 1OMJA 3HDAP 4XBHA 1XFWA 1Z3JA 1UTZA 2D1OA 1KAPP 3HBUP 4HMAA 2DDFA 3F1AA 5I43A 4AXQA 4G0DA 1GE6A 1JAOA 3UVCA 1JIZA 4J4MA 4GR3A 3G5CA 5BOTA 1A86A 4PKSA 4DF9A 4AUOA 4ILWD 4PKQA 5L79A 1SRPA 4L19A 2OVZA 1RMZA 2ERPA 4L6TA 3B2ZA 4DPEA 1MMQA 1SATA 2OW2A 1YP1A 1OS9A 5CXAA 3EHXA 1IAEA 1FLSA 1CGFA 2MZEA 4XCTA 3F15A 3EDGA 1CAQA 1QIBA 4WKIA 2K9CA 2E2DA 1QJIA 2KRJA 2AYKA 2OW1A 1C3IA 3KMCA 4R3VA 1AYKA 2XS3A 3AYUA 3EHYA 1O0QA 4JP4A 1BSWA 4H82A 5D1UA 2RJQA 3KECA 4FVLA 3DTKA 1JANA 3ZUKA 3LK8A 2POJA 5L7FA 3F19A 1JJ9A 3F18A 5D3CA 5H8XA 1JKYA 3EWJA 1BM6A 3LJGA 3BA0A 1A85A 5LABA 3AYKA 5I2ZA 1KUIA 3N2UA 4ON1A 4PKTA 1B3DA 1KUHA 2W13A 5B5PA 1GE5A 3DPEA 1K7QA 1OM6A 4JIJA 1WNIA 4L63A 1IACA 3DTEA 2X3BA 3K7NA 3DWBA 3EDIA 1USNA 4H1QA 1ASTA 4GF1A 3KEKA 1MMRA 2D1NA 1G12A 4AIGA 4IN9A 1MMPA 1G49A 3VTGA 2YB9A 2OXZA 2FV5A 3DNGA 3GBOA 3HYGA 3Q2HA 3LIRA 2X7MA 3G42A 1CXVA 1MNCA 1QJJA 3LJZA 1CK7A 1XAXA 3AIGA 4GWNA 4H3XA 3I7GA 3KRYA 1O0TA 1SLNA 1ZTQA 4WZVA 1D8MA 1R1IA 2FV9A 4GQLA 1TVIA 2MLRA 2RJPA 1XUCA 2Y6CA 4A3WA 1BKCA 1DMTA 2OW0A 4H49A 2OZRA 1ROSA 1IADA 3LQ0A 1IAGA 2JIHA 1R1HA 3B8ZA 1MMBA 1G4KA 1UTTA 1XFYA 1OO9A 4G9LA 4H84A 1KUFA 2USNA 3LJTA 3P24A 1D8FA 4XM8A 3WV3A 3LIKA 2OY2A 2WO8A 1S4BP 1JAQA 1GXDA 3LKAA 5I0LA 1Y8JA 3LILA 3RTSA 5BOYA 1JH1A 1Y0VA 3I7IA 3HY9A 1ND1A 1PWQA 1YCMA 2K2GA 3TT4A 1HY7A 4JA1A 1QUAA 2DW0A 4DV8A 1SMPA 2JNPA 1EUBA 2ERQA 1ZXVA 5D7WA 5D1TA 1B8YA 4PKWA 1EAKA 2L0RA 1YOUA 1D7XA 3K7LA 3ZXHA 4FXQA 4DD8A 3VI1A 2Z2DA 1G05A 2YIGA 3TSKA 4FXYP 1QIAA 1CGEA 1PWUA 1SLMA 3USNA 4H2EA 2X3CA 2OY4A 2V4BA 4GUYA 1IABA 1OM8A 4IUWA 4A7BA 3N2VA 1C8TA 4HX3A 2O3EA 1ZP5A 456CA 1D5JA 3L0TA 1KBCA 2WOAA 3LQBA 2HU6A 3KMEA 830CA 2WO9A 3U1RA 4JPAA 2OVXA 4WF6A 1Q3AA 1ATLA 1ZVXA 1FM1A 5I3MA 2W12A 3F16A 2E3XA 2N8RA
chains in the Genus database with same CATH topology
3TS4A 1JK3A 3V96B 4Q1LA 3LE9A 2MLSA 1SU3A 3B92A 3CKIA 3HB2P 3Q2GA 2J0TA 1BIWA 1ZXCA 1XURA 1FBLA 1R55A 3EDZA 2OXUA 3NX7A 5I4OA 1G9KA 5B5OA 4XM6A 5JMYA 1ZS0A 4CTHA 4EFSA 4ZR5A 4FU4A 1OS2A 4I35A 3KWVC 3EDHA 1PWPA 1UMSA 1HFSA 1RM8A 1R54A 1Y93A 2X3AA 1QICA 2DDYA 2QPJA 2EROA 3HDBA 2DW1A 4H30A 4PKRA 2JT5A 1I1IP 4XM7A 3MA2A 1K7IA 1HOVA 3HY7A 2A8HA 1I73A 1XFZA 2JT6A 3DPFA 2W0DA 4GR8A 1DTHA 1GKCA 1I76A 1BQOA 1K7GA 2DW2A 3DSLA 1BUVM 3O64A 1L6JA 1GE7A 3RTTA 1BUDA 4QKZA 1IAAA 1YQYA 1PWVA 1C7KA 2XS4A 3KEJA 3ELMA 5D2BA 2Y6DA 1BKCE 4PKVA 4IJOA 3LGPA 1GO7P 2SRTA 1GKDA 1CIZA 5D1SA 1PWWA 2CKIA 3E8RA 2CLTA 2MZIA 3LUMA 1AKLA 3DL1A 3LUNA 3TVCA 2OW9A 4L7AA 1J7NA 2AIGP 3KHIA 2W15A 1KUKA 1XFXA 4H76A 3P1VA 3L0VA 4AYKA 1HFCA 1CGLA 4WK7A 1KUGA 1JAPA 4GR0A 1BKCI 1HTDA 1BZSA 4WKEA 2O36A 1HV5A 1R1JA 1UEAA 3WV1A 1CQRA 3HBVP 3O2XA 2YUFA 1XFUA 3DTIA 3LMCA 1XFVA 1AF0A 3LEAA 2JSDA 3OHLA 1XUDA 1UMTA 5BPAA 4PKUA 2I47A 3OHOA 2OI0A 5CUHA 4I03A 3WV2A 2TCLA 1JIWP 966CA 2MZHA 1GO8P 5CZMA 3ZVSA 5I12A 1BQQM 4JQGA 1H71P 4GWMA 1EB6A 3F17A 3SHIA 2PJTA 2J83A 2OXWA 2W14A 1OM7A 1OMJA 3HDAP 4XBHA 1XFWA 1Z3JA 1UTZA 2D1OA 1KAPP 3HBUP 4HMAA 2DDFA 3F1AA 5I43A 4AXQA 4G0DA 1GE6A 1JAOA 3UVCA 1JIZA 4J4MA 4GR3A 3G5CA 5BOTA 1A86A 4PKSA 4DF9A 4AUOA 4ILWD 4PKQA 5L79A 1SRPA 4L19A 2OVZA 1RMZA 2ERPA 4L6TA 3B2ZA 4DPEA 1MMQA 1SATA 2OW2A 1YP1A 1OS9A 5CXAA 3EHXA 1IAEA 1FLSA 1CGFA 2MZEA 4XCTA 3F15A 3EDGA 1CAQA 1QIBA 4WKIA 2K9CA 2E2DA 1QJIA 2KRJA 2AYKA 2OW1A 1C3IA 3KMCA 4R3VA 1AYKA 2XS3A 3AYUA 3EHYA 1O0QA 4JP4A 1BSWA 4H82A 5D1UA 2RJQA 3KECA 4FVLA 3DTKA 1JANA 3ZUKA 3LK8A 2POJA 5L7FA 3F19A 1JJ9A 3F18A 5D3CA 5H8XA 1JKYA 3EWJA 1BM6A 3LJGA 3BA0A 1A85A 5LABA 3AYKA 5I2ZA 1KUIA 3N2UA 4ON1A 4PKTA 1B3DA 1KUHA 2W13A 5B5PA 1GE5A 3DPEA 1K7QA 1OM6A 4JIJA 1WNIA 4L63A 1IACA 3DTEA 2X3BA 3K7NA 3DWBA 3EDIA 1USNA 4H1QA 1ASTA 4GF1A 3KEKA 1MMRA 2D1NA 1G12A 4AIGA 4IN9A 1MMPA 1G49A 3VTGA 2YB9A 2OXZA 2FV5A 3DNGA 3GBOA 3HYGA 3Q2HA 3LIRA 2X7MA 3G42A 1CXVA 1MNCA 1QJJA 3LJZA 1CK7A 3AIGA 4GWNA 4H3XA 3I7GA 3KRYA 1O0TA 1SLNA 1ZTQA 4WZVA 1D8MA 1R1IA 2FV9A 4GQLA 2MLRA 2RJPA 1XUCA 2Y6CA 4A3WA 1BKCA 1DMTA 2OW0A 4H49A 2OZRA 1ROSA 1IADA 3LQ0A 1IAGA 2JIHA 1R1HA 3B8ZA 1MMBA 1G4KA 1UTTA 1XFYA 1OO9A 4G9LA 4H84A 1KUFA 2USNA 3LJTA 3P24A 1D8FA 4XM8A 3WV3A 3LIKA 2OY2A 2WO8A 1S4BP 1JAQA 1GXDA 3LKAA 5I0LA 1Y8JA 3LILA 3RTSA 5BOYA 1JH1A 1Y0VA 3I7IA 3HY9A 1ND1A 1PWQA 1YCMA 2K2GA 3TT4A 1HY7A 4JA1A 1QUAA 2DW0A 4DV8A 1SMPA 2JNPA 1EUBA 2ERQA 1ZXVA 5D7WA 5D1TA 1B8YA 4PKWA 1EAKA 2L0RA 1YOUA 1D7XA 3K7LA 3ZXHA 4FXQA 4DD8A 3VI1A 2Z2DA 1G05A 2YIGA 3TSKA 4FXYP 1QIAA 1CGEA 1PWUA 1SLMA 3USNA 4H2EA 2X3CA 2OY4A 2V4BA 4GUYA 1IABA 1OM8A 4IUWA 4A7BA 3N2VA 1C8TA 4HX3A 2O3EA 1ZP5A 456CA 1D5JA 3L0TA 1KBCA 2WOAA 3LQBA 2HU6A 3KMEA 830CA 2WO9A 3U1RA 4JPAA 2OVXA 4WF6A 1Q3AA 1ATLA 1ZVXA 1FM1A 5I3MA 2W12A 3F16A 2E3XA 2N8RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TS4 A;  1JK3 A;  3V96 B;  4Q1L A;  3LE9 A;  2MLS A;  1SU3 A;  3B92 A;  3CKI A;  3HB2 P;  3Q2G A;  2J0T A;  1BIW A;  1ZXC A;  1XUR A;  1FBL A;  1R55 A;  3EDZ A;  2OXU A;  3NX7 A;  5I4O A;  1G9K A;  5B5O A;  4XM6 A;  5JMY A;  1ZS0 A;  4CTH A;  4EFS A;  4ZR5 A;  4FU4 A;  1OS2 A;  4I35 A;  3KWV C;  3EDH A;  1PWP A;  1UMS A;  1HFS A;  1RM8 A;  1R54 A;  1Y93 A;  2X3A A;  1QIC A;  2DDY A;  2QPJ A;  2ERO A;  3HDB A;  2DW1 A;  4H30 A;  4PKR A;  2JT5 A;  1I1I P;  4XM7 A;  3MA2 A;  1K7I A;  1HOV A;  3HY7 A;  2A8H A;  1I73 A;  1XFZ A;  2JT6 A;  3DPF A;  2W0D A;  4GR8 A;  1DTH A;  1GKC A;  1I76 A;  1BQO A;  1K7G A;  2DW2 A;  3DSL A;  1BUV M;  3O64 A;  1L6J A;  1GE7 A;  3RTT A;  1BUD A;  4QKZ A;  1IAA A;  1YQY A;  1PWV A;  1C7K A;  2XS4 A;  3KEJ A;  3ELM A;  5D2B A;  2Y6D A;  1BKC E;  4PKV A;  4IJO A;  3LGP A;  1GO7 P;  2SRT A;  1GKD A;  1CIZ A;  5D1S A;  1PWW A;  2CKI A;  3E8R A;  2CLT A;  2MZI A;  3LUM A;  1AKL A;  3DL1 A;  3LUN A;  3TVC A;  2OW9 A;  1J7N A;  2AIG P;  3KHI A;  2W15 A;  1KUK A;  1XFX A;  4H76 A;  3P1V A;  3L0V A;  4AYK A;  1HFC A;  1CGL A;  4WK7 A;  1KUG A;  1JAP A;  4GR0 A;  1BKC I;  1HTD A;  1BZS A;  4WKE A;  2O36 A;  1HV5 A;  1R1J A;  1UEA A;  3WV1 A;  1CQR A;  3HBV P;  3O2X A;  1XFU A;  3LMC A;  1XFV A;  1AF0 A;  3LEA A;  2JSD A;  3OHL A;  1XUD A;  1UMT A;  5BPA A;  4PKU A;  2I47 A;  3OHO A;  2OI0 A;  5CUH A;  4I03 A;  3WV2 A;  2TCL A;  1JIW P;  966C A;  2MZH A;  1GO8 P;  5CZM A;  3ZVS A;  5I12 A;  1BQQ M;  4JQG A;  1H71 P;  4GWM A;  1EB6 A;  3F17 A;  3SHI A;  2PJT A;  2J83 A;  2OXW A;  2W14 A;  1OM7 A;  1OMJ A;  3HDA P;  4XBH A;  1XFW A;  1Z3J A;  1UTZ A;  2D1O A;  1KAP P;  3HBU P;  4HMA A;  2DDF A;  3F1A A;  5I43 A;  4AXQ A;  4G0D A;  1GE6 A;  1JAO A;  3UVC A;  1JIZ A;  4J4M A;  4GR3 A;  3G5C A;  5BOT A;  1A86 A;  4PKS A;  4DF9 A;  4AUO A;  4ILW D;  4PKQ A;  5L79 A;  1SRP A;  4L19 A;  2OVZ A;  1RMZ A;  2ERP A;  4L6T A;  3B2Z A;  4DPE A;  1MMQ A;  1SAT A;  2OW2 A;  1YP1 A;  1OS9 A;  5CXA A;  3EHX A;  1IAE A;  1FLS A;  1CGF A;  2MZE A;  4XCT A;  3F15 A;  3EDG A;  1CAQ A;  1QIB A;  4WKI A;  2K9C A;  2E2D A;  1QJI A;  2KRJ A;  2AYK A;  2OW1 A;  1C3I A;  3KMC A;  4R3V A;  1AYK A;  2XS3 A;  3AYU A;  3EHY A;  1O0Q A;  4JP4 A;  1BSW A;  4H82 A;  5D1U A;  2RJQ A;  3KEC A;  4FVL A;  1JAN A;  3ZUK A;  3LK8 A;  2POJ A;  5L7F A;  3F19 A;  1JJ9 A;  3F18 A;  5D3C A;  5H8X A;  1JKY A;  3EWJ A;  1BM6 A;  3LJG A;  3BA0 A;  1A85 A;  5LAB A;  3AYK A;  5I2Z A;  1KUI A;  3N2U A;  4ON1 A;  4PKT A;  1B3D A;  1KUH A;  2W13 A;  5B5P A;  1GE5 A;  3DPE A;  1K7Q A;  1OM6 A;  4JIJ A;  1WNI A;  4L63 A;  1IAC A;  2X3B A;  3K7N A;  3DWB A;  3EDI A;  1USN A;  4H1Q A;  1AST A;  4GF1 A;  3KEK A;  1MMR A;  2D1N A;  1G12 A;  4AIG A;  4IN9 A;  1MMP A;  1G49 A;  3VTG A;  2YB9 A;  2OXZ A;  2FV5 A;  3DNG A;  3GBO A;  3HYG A;  3Q2H A;  3LIR A;  2X7M A;  3G42 A;  1CXV A;  1MNC A;  1QJJ A;  3LJZ A;  1CK7 A;  3AIG A;  4GWN A;  4H3X A;  3I7G A;  3KRY A;  1O0T A;  1SLN A;  1ZTQ A;  4WZV A;  1D8M A;  1R1I A;  2FV9 A;  4GQL A;  2MLR A;  2RJP A;  1XUC A;  2Y6C A;  4A3W A;  1BKC A;  1DMT A;  2OW0 A;  4H49 A;  2OZR A;  1ROS A;  1IAD A;  3LQ0 A;  1IAG A;  2JIH A;  1R1H A;  3B8Z A;  1MMB A;  1G4K A;  1UTT A;  1XFY A;  1OO9 A;  4G9L A;  4H84 A;  1KUF A;  2USN A;  3LJT A;  3P24 A;  1D8F A;  4XM8 A;  3WV3 A;  3LIK A;  2OY2 A;  2WO8 A;  1S4B P;  1JAQ A;  1GXD A;  3LKA A;  5I0L A;  1Y8J A;  3LIL A;  3RTS A;  5BOY A;  1JH1 A;  1Y0V A;  3I7I A;  3HY9 A;  1ND1 A;  1PWQ A;  1YCM A;  2K2G A;  3TT4 A;  1HY7 A;  4JA1 A;  1QUA A;  2DW0 A;  4DV8 A;  1SMP A;  2JNP A;  1EUB A;  2ERQ A;  1ZXV A;  5D7W A;  5D1T A;  1B8Y A;  4PKW A;  1EAK A;  2L0R A;  1YOU A;  1D7X A;  3K7L A;  3ZXH A;  4FXQ A;  4DD8 A;  3VI1 A;  2Z2D A;  1G05 A;  2YIG A;  3TSK A;  4FXY P;  1QIA A;  1CGE A;  1PWU A;  1SLM A;  3USN A;  4H2E A;  2X3C A;  2OY4 A;  2V4B A;  4GUY A;  1IAB A;  1OM8 A;  4IUW A;  4A7B A;  3N2V A;  1C8T A;  4HX3 A;  2O3E A;  1ZP5 A;  456C A;  1D5J A;  3L0T A;  1KBC A;  2WOA A;  3LQB A;  2HU6 A;  3KME A;  830C A;  2WO9 A;  3U1R A;  4JPA A;  2OVX A;  4WF6 A;  1Q3A A;  1ATL A;  1ZVX A;  1FM1 A;  5I3M A;  2W12 A;  3F16 A;  2E3X A;  2N8R A; 
#chains in the Genus database with same CATH topology
 3TS4 A;  1JK3 A;  3V96 B;  4Q1L A;  3LE9 A;  2MLS A;  1SU3 A;  3B92 A;  3CKI A;  3HB2 P;  3Q2G A;  2J0T A;  1BIW A;  1ZXC A;  1XUR A;  1FBL A;  1R55 A;  3EDZ A;  2OXU A;  3NX7 A;  5I4O A;  1G9K A;  5B5O A;  4XM6 A;  5JMY A;  1ZS0 A;  4CTH A;  4EFS A;  4ZR5 A;  4FU4 A;  1OS2 A;  4I35 A;  3KWV C;  3EDH A;  1PWP A;  1UMS A;  1HFS A;  1RM8 A;  1R54 A;  1Y93 A;  2X3A A;  1QIC A;  2DDY A;  1OZ9 A;  2QPJ A;  2ERO A;  3HDB A;  2DW1 A;  4H30 A;  4PKR A;  2JT5 A;  1I1I P;  4XM7 A;  3MA2 A;  1K7I A;  1HOV A;  3HY7 A;  2A8H A;  1I73 A;  1XFZ A;  2JT6 A;  3DPF A;  2W0D A;  4GR8 A;  1DTH A;  1GKC A;  1I76 A;  1BQO A;  1K7G A;  2DW2 A;  3DSL A;  1BUV M;  3O64 A;  1L6J A;  1GE7 A;  3RTT A;  1BUD A;  4QKZ A;  1IAA A;  1YQY A;  1PWV A;  1C7K A;  2XS4 A;  3KEJ A;  3ELM A;  5D2B A;  2Y6D A;  1BKC E;  4PKV A;  4IJO A;  3LGP A;  1GO7 P;  2SRT A;  1GKD A;  1CIZ A;  5D1S A;  1PWW A;  2CKI A;  3E8R A;  2CLT A;  2MZI A;  3LUM A;  1AKL A;  3DL1 A;  3LUN A;  3TVC A;  2OW9 A;  4L7A A;  1J7N A;  2AIG P;  3KHI A;  2W15 A;  1KUK A;  1XFX A;  4H76 A;  3P1V A;  3L0V A;  4AYK A;  1HFC A;  1CGL A;  4WK7 A;  1KUG A;  1JAP A;  4GR0 A;  1BKC I;  1HTD A;  1BZS A;  4WKE A;  2O36 A;  1HV5 A;  1R1J A;  1UEA A;  3WV1 A;  1CQR A;  3HBV P;  3O2X A;  1XM5 A;  2YUF A;  1XFU A;  3DTI A;  3LMC A;  1XFV A;  1AF0 A;  3LEA A;  2JSD A;  3OHL A;  1XUD A;  1UMT A;  5BPA A;  4PKU A;  2I47 A;  3OHO A;  2OI0 A;  5CUH A;  4I03 A;  3WV2 A;  2TCL A;  1JIW P;  966C A;  2MZH A;  1GO8 P;  5CZM A;  3ZVS A;  5I12 A;  1BQQ M;  4JQG A;  1H71 P;  4GWM A;  1EB6 A;  3F17 A;  3SHI A;  2PJT A;  2J83 A;  2OXW A;  2W14 A;  1OM7 A;  1OMJ A;  3HDA P;  4XBH A;  1XFW A;  1Z3J A;  1UTZ A;  2D1O A;  1KAP P;  3HBU P;  4HMA A;  2DDF A;  3F1A A;  5I43 A;  4AXQ A;  4G0D A;  1GE6 A;  1JAO A;  3UVC A;  1JIZ A;  4J4M A;  4GR3 A;  3G5C A;  5BOT A;  1A86 A;  4PKS A;  4DF9 A;  4AUO A;  4ILW D;  4PKQ A;  5L79 A;  1SRP A;  4L19 A;  2OVZ A;  1RMZ A;  2ERP A;  4L6T A;  3B2Z A;  4DPE A;  1MMQ A;  1SAT A;  2OW2 A;  1YP1 A;  1OS9 A;  5CXA A;  3EHX A;  1IAE A;  1FLS A;  1CGF A;  2MZE A;  4XCT A;  3F15 A;  3EDG A;  1CAQ A;  1QIB A;  4WKI A;  2K9C A;  2E2D A;  1QJI A;  2KRJ A;  2AYK A;  2OW1 A;  1C3I A;  3KMC A;  4R3V A;  1AYK A;  2XS3 A;  3AYU A;  3EHY A;  1O0Q A;  4JP4 A;  1BSW A;  4H82 A;  5D1U A;  2RJQ A;  3KEC A;  4FVL A;  3DTK A;  1JAN A;  3ZUK A;  3LK8 A;  2POJ A;  5L7F A;  3F19 A;  1JJ9 A;  3F18 A;  5D3C A;  5H8X A;  1JKY A;  3EWJ A;  1BM6 A;  3LJG A;  3BA0 A;  1A85 A;  5LAB A;  3AYK A;  5I2Z A;  1KUI A;  3N2U A;  4ON1 A;  4PKT A;  1B3D A;  1KUH A;  2W13 A;  5B5P A;  1GE5 A;  3DPE A;  1K7Q A;  1OM6 A;  4JIJ A;  1WNI A;  4L63 A;  1IAC A;  3DTE A;  2X3B A;  3K7N A;  3DWB A;  3EDI A;  1USN A;  4H1Q A;  1AST A;  4GF1 A;  3KEK A;  1MMR A;  2D1N A;  1G12 A;  4AIG A;  4IN9 A;  1MMP A;  1G49 A;  3VTG A;  2YB9 A;  2OXZ A;  2FV5 A;  3DNG A;  3GBO A;  3HYG A;  3Q2H A;  3LIR A;  2X7M A;  3G42 A;  1CXV A;  1MNC A;  1QJJ A;  3LJZ A;  1CK7 A;  1XAX A;  3AIG A;  4GWN A;  4H3X A;  3I7G A;  3KRY A;  1O0T A;  1SLN A;  1ZTQ A;  4WZV A;  1D8M A;  1R1I A;  2FV9 A;  4GQL A;  1TVI A;  2MLR A;  2RJP A;  1XUC A;  2Y6C A;  4A3W A;  1BKC A;  1DMT A;  2OW0 A;  4H49 A;  2OZR A;  1ROS A;  1IAD A;  3LQ0 A;  1IAG A;  2JIH A;  1R1H A;  3B8Z A;  1MMB A;  1G4K A;  1UTT A;  1XFY A;  1OO9 A;  4G9L A;  4H84 A;  1KUF A;  2USN A;  3LJT A;  3P24 A;  1D8F A;  4XM8 A;  3WV3 A;  3LIK A;  2OY2 A;  2WO8 A;  1S4B P;  1JAQ A;  1GXD A;  3LKA A;  5I0L A;  1Y8J A;  3LIL A;  3RTS A;  5BOY A;  1JH1 A;  1Y0V A;  3I7I A;  3HY9 A;  1ND1 A;  1PWQ A;  1YCM A;  2K2G A;  3TT4 A;  1HY7 A;  4JA1 A;  1QUA A;  2DW0 A;  4DV8 A;  1SMP A;  2JNP A;  1EUB A;  2ERQ A;  1ZXV A;  5D7W A;  5D1T A;  1B8Y A;  4PKW A;  1EAK A;  2L0R A;  1YOU A;  1D7X A;  3K7L A;  3ZXH A;  4FXQ A;  4DD8 A;  3VI1 A;  2Z2D A;  1G05 A;  2YIG A;  3TSK A;  4FXY P;  1QIA A;  1CGE A;  1PWU A;  1SLM A;  3USN A;  4H2E A;  2X3C A;  2OY4 A;  2V4B A;  4GUY A;  1IAB A;  1OM8 A;  4IUW A;  4A7B A;  3N2V A;  1C8T A;  4HX3 A;  2O3E A;  1ZP5 A;  456C A;  1D5J A;  3L0T A;  1KBC A;  2WOA A;  3LQB A;  2HU6 A;  3KME A;  830C A;  2WO9 A;  3U1R A;  4JPA A;  2OVX A;  4WF6 A;  1Q3A A;  1ATL A;  1ZVX A;  1FM1 A;  5I3M A;  2W12 A;  3F16 A;  2E3X A;  2N8R A; 
#chains in the Genus database with same CATH homology
 3TS4 A;  1JK3 A;  3V96 B;  4Q1L A;  3LE9 A;  2MLS A;  1SU3 A;  3B92 A;  3CKI A;  3HB2 P;  3Q2G A;  2J0T A;  1BIW A;  1ZXC A;  1XUR A;  1FBL A;  1R55 A;  3EDZ A;  2OXU A;  3NX7 A;  5I4O A;  1G9K A;  5B5O A;  4XM6 A;  5JMY A;  1ZS0 A;  4CTH A;  4EFS A;  4ZR5 A;  4FU4 A;  1OS2 A;  4I35 A;  3KWV C;  3EDH A;  1PWP A;  1UMS A;  1HFS A;  1RM8 A;  1R54 A;  1Y93 A;  2X3A A;  1QIC A;  2DDY A;  2QPJ A;  2ERO A;  3HDB A;  2DW1 A;  4H30 A;  4PKR A;  2JT5 A;  1I1I P;  4XM7 A;  3MA2 A;  1K7I A;  1HOV A;  3HY7 A;  2A8H A;  1I73 A;  1XFZ A;  2JT6 A;  3DPF A;  2W0D A;  4GR8 A;  1DTH A;  1GKC A;  1I76 A;  1BQO A;  1K7G A;  2DW2 A;  3DSL A;  1BUV M;  3O64 A;  1L6J A;  1GE7 A;  3RTT A;  1BUD A;  4QKZ A;  1IAA A;  1YQY A;  1PWV A;  1C7K A;  2XS4 A;  3KEJ A;  3ELM A;  5D2B A;  2Y6D A;  1BKC E;  4PKV A;  4IJO A;  3LGP A;  1GO7 P;  2SRT A;  1GKD A;  1CIZ A;  5D1S A;  1PWW A;  2CKI A;  3E8R A;  2CLT A;  2MZI A;  3LUM A;  1AKL A;  3DL1 A;  3LUN A;  3TVC A;  2OW9 A;  4L7A A;  1J7N A;  2AIG P;  3KHI A;  2W15 A;  1KUK A;  1XFX A;  4H76 A;  3P1V A;  3L0V A;  4AYK A;  1HFC A;  1CGL A;  4WK7 A;  1KUG A;  1JAP A;  4GR0 A;  1BKC I;  1HTD A;  1BZS A;  4WKE A;  2O36 A;  1HV5 A;  1R1J A;  1UEA A;  3WV1 A;  1CQR A;  3HBV P;  3O2X A;  2YUF A;  1XFU A;  3DTI A;  3LMC A;  1XFV A;  1AF0 A;  3LEA A;  2JSD A;  3OHL A;  1XUD A;  1UMT A;  5BPA A;  4PKU A;  2I47 A;  3OHO A;  2OI0 A;  5CUH A;  4I03 A;  3WV2 A;  2TCL A;  1JIW P;  966C A;  2MZH A;  1GO8 P;  5CZM A;  3ZVS A;  5I12 A;  1BQQ M;  4JQG A;  1H71 P;  4GWM A;  1EB6 A;  3F17 A;  3SHI A;  2PJT A;  2J83 A;  2OXW A;  2W14 A;  1OM7 A;  1OMJ A;  3HDA P;  4XBH A;  1XFW A;  1Z3J A;  1UTZ A;  2D1O A;  1KAP P;  3HBU P;  4HMA A;  2DDF A;  3F1A A;  5I43 A;  4AXQ A;  4G0D A;  1GE6 A;  1JAO A;  3UVC A;  1JIZ A;  4J4M A;  4GR3 A;  3G5C A;  5BOT A;  1A86 A;  4PKS A;  4DF9 A;  4AUO A;  4ILW D;  4PKQ A;  5L79 A;  1SRP A;  4L19 A;  2OVZ A;  1RMZ A;  2ERP A;  4L6T A;  3B2Z A;  4DPE A;  1MMQ A;  1SAT A;  2OW2 A;  1YP1 A;  1OS9 A;  5CXA A;  3EHX A;  1IAE A;  1FLS A;  1CGF A;  2MZE A;  4XCT A;  3F15 A;  3EDG A;  1CAQ A;  1QIB A;  4WKI A;  2K9C A;  2E2D A;  1QJI A;  2KRJ A;  2AYK A;  2OW1 A;  1C3I A;  3KMC A;  4R3V A;  1AYK A;  2XS3 A;  3AYU A;  3EHY A;  1O0Q A;  4JP4 A;  1BSW A;  4H82 A;  5D1U A;  2RJQ A;  3KEC A;  4FVL A;  3DTK A;  1JAN A;  3ZUK A;  3LK8 A;  2POJ A;  5L7F A;  3F19 A;  1JJ9 A;  3F18 A;  5D3C A;  5H8X A;  1JKY A;  3EWJ A;  1BM6 A;  3LJG A;  3BA0 A;  1A85 A;  5LAB A;  3AYK A;  5I2Z A;  1KUI A;  3N2U A;  4ON1 A;  4PKT A;  1B3D A;  1KUH A;  2W13 A;  5B5P A;  1GE5 A;  3DPE A;  1K7Q A;  1OM6 A;  4JIJ A;  1WNI A;  4L63 A;  1IAC A;  3DTE A;  2X3B A;  3K7N A;  3DWB A;  3EDI A;  1USN A;  4H1Q A;  1AST A;  4GF1 A;  3KEK A;  1MMR A;  2D1N A;  1G12 A;  4AIG A;  4IN9 A;  1MMP A;  1G49 A;  3VTG A;  2YB9 A;  2OXZ A;  2FV5 A;  3DNG A;  3GBO A;  3HYG A;  3Q2H A;  3LIR A;  2X7M A;  3G42 A;  1CXV A;  1MNC A;  1QJJ A;  3LJZ A;  1CK7 A;  3AIG A;  4GWN A;  4H3X A;  3I7G A;  3KRY A;  1O0T A;  1SLN A;  1ZTQ A;  4WZV A;  1D8M A;  1R1I A;  2FV9 A;  4GQL A;  2MLR A;  2RJP A;  1XUC A;  2Y6C A;  4A3W A;  1BKC A;  1DMT A;  2OW0 A;  4H49 A;  2OZR A;  1ROS A;  1IAD A;  3LQ0 A;  1IAG A;  2JIH A;  1R1H A;  3B8Z A;  1MMB A;  1G4K A;  1UTT A;  1XFY A;  1OO9 A;  4G9L A;  4H84 A;  1KUF A;  2USN A;  3LJT A;  3P24 A;  1D8F A;  4XM8 A;  3WV3 A;  3LIK A;  2OY2 A;  2WO8 A;  1S4B P;  1JAQ A;  1GXD A;  3LKA A;  5I0L A;  1Y8J A;  3LIL A;  3RTS A;  5BOY A;  1JH1 A;  1Y0V A;  3I7I A;  3HY9 A;  1ND1 A;  1PWQ A;  1YCM A;  2K2G A;  3TT4 A;  1HY7 A;  4JA1 A;  1QUA A;  2DW0 A;  4DV8 A;  1SMP A;  2JNP A;  1EUB A;  2ERQ A;  1ZXV A;  5D7W A;  5D1T A;  1B8Y A;  4PKW A;  1EAK A;  2L0R A;  1YOU A;  1D7X A;  3K7L A;  3ZXH A;  4FXQ A;  4DD8 A;  3VI1 A;  2Z2D A;  1G05 A;  2YIG A;  3TSK A;  4FXY P;  1QIA A;  1CGE A;  1PWU A;  1SLM A;  3USN A;  4H2E A;  2X3C A;  2OY4 A;  2V4B A;  4GUY A;  1IAB A;  1OM8 A;  4IUW A;  4A7B A;  3N2V A;  1C8T A;  4HX3 A;  2O3E A;  1ZP5 A;  456C A;  1D5J A;  3L0T A;  1KBC A;  2WOA A;  3LQB A;  2HU6 A;  3KME A;  830C A;  2WO9 A;  3U1R A;  4JPA A;  2OVX A;  4WF6 A;  1Q3A A;  1ATL A;  1ZVX A;  1FM1 A;  5I3M A;  2W12 A;  3F16 A;  2E3X A;  2N8R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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