2TCLA

Structure of the catalytic domain of human fibroblast collagenase complexed with an inhibitor
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
163
structure length
163
Chain Sequence
LTEGNPRWEQTHLTYRIENYTPDLPRADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGNLAHAFQPGPGIGGDAHFDEDERWTNNFREYNLHRVAAHELGHSLGLSHSTDIGALMYPSYTFSGDVQLAQDDIDGIQAIYGRSQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the catalytic domain of human fibroblast collagenase complexed with an inhibitor.
pubmed doi rcsb
molecule tags Hydrolase (metalloprotease)
molecule keywords FIBROBLAST COLLAGENASE
total genus 47
structure length 163
sequence length 163
ec nomenclature ec 3.4.24.7: Interstitial collagenase.
pdb deposition date 1994-09-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 2tclA00
1GO8P 4WKIA 1G4KA 5D1TA 1JJ9A 3I7IA 3HY7A 4L19A 1I76A 4GWNA 2XS3A 3F19A 5D3CA 2HU6A 1JIWP 1H71P 1UTTA 4JPAA 3RTSA 2D1NA 1SLMA 4PKTA 4FXQA 1JK3A 3EHXA 4PKUA 4FVLA 3LGPA 1ATLA 1EAKA 1BSWA 2JIHA 966CA 2WO8A 3LK8A 3BA0A 2FV9A 1G9KA 3O2XA 1IAAA 1GE5A 1MMQA 1Z3JA 1C8TA 1I1IP 3LMCA 1HFSA 1ND1A 4JIJA 1R54A 1A86A 3KRYA 4WK7A 3LJTA 1QUAA 3HDBA 3Q2GA 1OS9A 2DDYA 1BM6A 1QIBA 1K7IA 2SRTA 3HY9A 1XFVA 1OS2A 1QJIA 4HMAA 3EHYA 4GWMA 2USNA 1SLNA 1PWQA 2O36A 2K2GA 1MMPA 1IABA 1UMTA 5I3MA 1EUBA 3LKAA 1B3DA 1AF0A 4XCTA 3G5CA 1MMBA 2E3XA 3LE9A 2OW9A 2MLSA 4H3XA 2D1OA 5L79A 2TCLA 2MZEA 3OHLA 4GUYA 3P24A 3LUMA 4GQLA 1BUDA 1Y8JA 4AXQA 4H82A 4G9LA 3DL1A 2E2DA 4XBHA 2ERPA 2L0RA 4HX3A 1ZP5A 2JSDA 2DDFA 1UTZA 830CA 1GO7P 5D1SA 2YIGA 4R3VA 2OI0A 4G0DA 2A8HA 4WKEA 1D8FA 2W14A 1GXDA 2MZHA 2OXWA 1GE7A 2K9CA 4I35A 1EB6A 1PWVA 2DW0A 5B5PA 5D7WA 1RM8A 3DPFA 1KAPP 1UMSA 2AIGP 4H49A 1DTHA 2JT6A 3EWJA 1XURA 1IAEA 4IUWA 1K7QA 3UVCA 4H30A 1DMTA 1ZS0A 2O3EA 1BKCI 4PKRA 1YOUA 3RTTA 1CIZA 3K7LA 1XFYA 1GE6A 1WNIA 3LILA 3DWBA 1Y0VA 3WV1A 3TS4A 2DW2A 3HYGA 2FV5A 1D8MA 3B92A 1KUKA 2JT5A 4PKWA 1XFWA 4JQGA 3KEKA 1ZTQA 3LQBA 1R1HA 3NX7A 4PKQA 4XM6A 2POJA 2WO9A 1CAQA 3EDIA 3HDAP 1CXVA 2OXZA 3CKIA 1RMZA 1FBLA 1A85A 1O0QA 3EDGA 3LEAA 3V96B 2N8RA 3KMEA 1OM7A 3B8ZA 3KMCA 1R1IA 2OY2A 1Q3AA 3AIGA 3L0VA 3ZXHA 3DSLA 1HTDA 3I7GA 2KRJA 3AYKA 3F17A 4PKSA 1CGEA 3WV2A 5D2BA 5LABA 456CA 5CZMA 3O64A 3WV3A 1JKYA 4A3WA 4GR3A 2EROA 1SRPA 2JNPA 1K7GA 2J83A 4DD8A 5CUHA 2OY4A 1OO9A 1C7KA 2XS4A 4L63A 5I2ZA 1KUFA 2J0TA 1XFZA 4A7BA 1OM6A 2WOAA 3F1AA 4JP4A 4CTHA 2Y6CA 2Y6DA 4DV8A 3TVCA 2AYKA 5D1UA 3E8RA 1IAGA 1ZXVA 2OW1A 4ILWD 3LUNA 1JAPA 1MNCA 1JAQA 1XUCA 4Q1LA 2QPJA 3KWVC 1IACA 4IJOA 1YP1A 3ELMA 1OMJA 1D7XA 3TT4A 3USNA 3U1RA 1PWPA 4H76A 3EDHA 3HBUP 2W13A 1IADA 1PWWA 2X3CA 3Q2HA 4EFSA 3HBVP 3HB2P 2W15A 1BZSA 3L0TA 3KECA 4DPEA 1JAOA 1R55A 1SMPA 1YQYA 1MMRA 1KUGA 4L6TA 3VTGA 5JMYA 4PKVA 1G05A 3LJZA 4GR8A 4IN9A 2OXUA 4FU4A 2OW0A 5L7FA 5CXAA 5BOTA 4FXYP 2W0DA 1BQOA 4AYKA 3OHOA 1ROSA 1ZVXA 4XM7A 2ERQA 1QIAA 3LJGA 4I03A 4H1QA 1QICA 1FLSA 1HOVA 1YCMA 2MZIA 1BKCA 2RJQA 1I73A 1AYKA 2W12A 3SHIA 1PWUA 1G49A 1CQRA 5I4OA 3B2ZA 2DW1A 2PJTA 4AUOA 4AIGA 2X7MA 1CGFA 2I47A 3EDZA 3ZVSA 5BPAA 1BUVM 1XFUA 3LIRA 3DPEA 1KUHA 2YB9A 3LQ0A 3KHIA 1JANA 4H2EA 1HY7A 1USNA 1R1JA 4DF9A 1OM8A 5B5OA 1ASTA 1J7NA 5BOYA 5I0LA 2OVXA 1CK7A 4XM8A 2V4BA 3KEJA 3GBOA 3F16A 1HV5A 2OVZA 2MLRA 3VI1A 3P1VA 1L6JA 1KUIA 1GKCA 3MA2A 1G12A 1XFXA 1O0TA 3G42A 4WZVA 1C3IA 4ON1A 1KBCA 2Z2DA 3K7NA 3TSKA 1BKCE 2CLTA 4J4MA 2X3AA 5I12A 1BIWA 1CGLA 3DNGA 1Y93A 1B8YA 1QJJA 1S4BP 3ZUKA 4GF1A 5H8XA 2X3BA 4ZR5A 2RJPA 1SATA 4QKZA 3N2UA 1D5JA 4GR0A 4JA1A 2OZRA 1JH1A 3AYUA 1JIZA 5I43A 1SU3A 1ZXCA 2CKIA 1UEAA 1GKDA 2OW2A 1FM1A 3F18A 1AKLA 1BQQM 4H84A 1HFCA 3F15A 4WF6A 1XUDA 3LIKA 3N2VA
chains in the Genus database with same CATH superfamily
1GO8P 4WKIA 1G4KA 5D1TA 1JJ9A 3I7IA 3HY7A 4L19A 1I76A 4GWNA 2XS3A 3F19A 5D3CA 2HU6A 1JIWP 1H71P 1UTTA 4JPAA 3RTSA 2D1NA 1SLMA 4PKTA 4FXQA 1JK3A 3EHXA 4PKUA 4FVLA 3LGPA 1ATLA 1EAKA 1BSWA 2JIHA 966CA 2WO8A 3LK8A 3BA0A 2FV9A 1G9KA 3O2XA 1IAAA 1GE5A 1MMQA 1Z3JA 1C8TA 1I1IP 3LMCA 1HFSA 1ND1A 4JIJA 1R54A 1A86A 3KRYA 4WK7A 3LJTA 1QUAA 3HDBA 3Q2GA 1OS9A 2DDYA 1BM6A 1QIBA 1K7IA 2SRTA 3HY9A 1XFVA 1OS2A 1QJIA 2YUFA 4HMAA 3EHYA 4GWMA 2USNA 1SLNA 1PWQA 2O36A 2K2GA 1MMPA 1IABA 1UMTA 5I3MA 1EUBA 3LKAA 1B3DA 1AF0A 4XCTA 3G5CA 1MMBA 2E3XA 3LE9A 2OW9A 2MLSA 4H3XA 2D1OA 5L79A 2TCLA 2MZEA 3OHLA 4GUYA 3P24A 3LUMA 4GQLA 1BUDA 1Y8JA 4AXQA 4H82A 4G9LA 3DL1A 2E2DA 4XBHA 2ERPA 2L0RA 4HX3A 1ZP5A 2JSDA 2DDFA 1UTZA 830CA 1GO7P 5D1SA 2YIGA 4R3VA 2OI0A 4G0DA 2A8HA 4WKEA 1D8FA 2W14A 1GXDA 2MZHA 2OXWA 1GE7A 2K9CA 4I35A 1XM5A 1EB6A 1PWVA 2DW0A 5B5PA 5D7WA 1RM8A 3DPFA 1KAPP 1UMSA 2AIGP 4H49A 1DTHA 2JT6A 3EWJA 1XURA 1IAEA 4IUWA 1K7QA 3UVCA 4H30A 1DMTA 1ZS0A 2O3EA 1BKCI 4PKRA 1YOUA 3RTTA 1CIZA 3K7LA 1XFYA 1GE6A 1WNIA 3LILA 3DWBA 1Y0VA 3WV1A 3TS4A 2DW2A 3HYGA 2FV5A 1D8MA 3B92A 1KUKA 2JT5A 4PKWA 1XFWA 4JQGA 3KEKA 1ZTQA 3LQBA 1R1HA 3NX7A 4PKQA 4L7AA 4XM6A 2POJA 2WO9A 1CAQA 3EDIA 3HDAP 1CXVA 2OXZA 3CKIA 1RMZA 1FBLA 1A85A 1O0QA 3EDGA 3LEAA 3V96B 2N8RA 3KMEA 1OM7A 3B8ZA 3KMCA 1R1IA 2OY2A 1Q3AA 3AIGA 3L0VA 3ZXHA 3DSLA 1HTDA 3I7GA 2KRJA 3AYKA 3F17A 4PKSA 1CGEA 3WV2A 3DTKA 5D2BA 5LABA 456CA 5CZMA 3O64A 3WV3A 1JKYA 4A3WA 3DTEA 4GR3A 2EROA 1SRPA 2JNPA 1K7GA 2J83A 4DD8A 5CUHA 2OY4A 1OO9A 1C7KA 2XS4A 4L63A 5I2ZA 1KUFA 2J0TA 1XFZA 4A7BA 1OM6A 2WOAA 3F1AA 4JP4A 4CTHA 2Y6CA 2Y6DA 4DV8A 3TVCA 2AYKA 5D1UA 3E8RA 1IAGA 1ZXVA 2OW1A 4ILWD 3LUNA 1JAPA 1MNCA 1JAQA 1XUCA 4Q1LA 2QPJA 3KWVC 1IACA 4IJOA 1YP1A 3ELMA 1OMJA 1D7XA 3TT4A 3USNA 3U1RA 1PWPA 4H76A 3EDHA 3HBUP 2W13A 1IADA 1PWWA 2X3CA 3Q2HA 4EFSA 3HBVP 3HB2P 2W15A 1BZSA 3L0TA 3KECA 4DPEA 1JAOA 1R55A 1SMPA 1YQYA 1MMRA 1KUGA 4L6TA 1OZ9A 3VTGA 5JMYA 4PKVA 1G05A 3LJZA 4GR8A 4IN9A 2OXUA 4FU4A 2OW0A 5L7FA 5CXAA 5BOTA 4FXYP 2W0DA 1BQOA 3DTIA 4AYKA 3OHOA 1ROSA 1ZVXA 4XM7A 2ERQA 1QIAA 3LJGA 4I03A 4H1QA 1QICA 1FLSA 1HOVA 1YCMA 2MZIA 1BKCA 2RJQA 1I73A 1AYKA 2W12A 3SHIA 1PWUA 1G49A 1CQRA 5I4OA 3B2ZA 2DW1A 2PJTA 4AUOA 4AIGA 2X7MA 1CGFA 2I47A 3EDZA 3ZVSA 5BPAA 1BUVM 1XFUA 3LIRA 3DPEA 1KUHA 2YB9A 3LQ0A 3KHIA 1JANA 4H2EA 1HY7A 1USNA 1R1JA 4DF9A 1OM8A 5B5OA 1ASTA 1J7NA 5BOYA 5I0LA 2OVXA 1CK7A 1XAXA 4XM8A 2V4BA 3KEJA 3GBOA 3F16A 1HV5A 2OVZA 2MLRA 3VI1A 3P1VA 1L6JA 1KUIA 1GKCA 3MA2A 1G12A 1XFXA 1O0TA 3G42A 4WZVA 1C3IA 4ON1A 1KBCA 2Z2DA 3K7NA 3TSKA 1BKCE 2CLTA 1TVIA 4J4MA 2X3AA 5I12A 1BIWA 1CGLA 3DNGA 1Y93A 1B8YA 1QJJA 1S4BP 3ZUKA 4GF1A 5H8XA 2X3BA 4ZR5A 2RJPA 1SATA 4QKZA 3N2UA 1D5JA 4GR0A 4JA1A 2OZRA 1JH1A 3AYUA 1JIZA 5I43A 1SU3A 1ZXCA 2CKIA 1UEAA 1GKDA 2OW2A 1FM1A 3F18A 1AKLA 1BQQM 4H84A 1HFCA 3F15A 4WF6A 1XUDA 3LIKA 3N2VA
chains in the Genus database with same CATH topology
1GO8P 4WKIA 1G4KA 5D1TA 1JJ9A 3I7IA 3HY7A 4L19A 1I76A 4GWNA 2XS3A 3F19A 5D3CA 2HU6A 1JIWP 1H71P 1UTTA 4JPAA 3RTSA 2D1NA 1SLMA 4PKTA 4FXQA 1JK3A 3EHXA 4PKUA 4FVLA 3LGPA 1ATLA 1EAKA 1BSWA 2JIHA 966CA 2WO8A 3LK8A 3BA0A 2FV9A 1G9KA 3O2XA 1IAAA 1GE5A 1MMQA 1Z3JA 1C8TA 1I1IP 3LMCA 1HFSA 1ND1A 4JIJA 1R54A 1A86A 3KRYA 4WK7A 3LJTA 1QUAA 3HDBA 3Q2GA 1OS9A 2DDYA 1BM6A 1QIBA 1K7IA 2SRTA 3HY9A 1XFVA 1OS2A 1QJIA 2YUFA 4HMAA 3EHYA 4GWMA 2USNA 1SLNA 1PWQA 2O36A 2K2GA 1MMPA 1IABA 1UMTA 5I3MA 1EUBA 3LKAA 1B3DA 1AF0A 4XCTA 3G5CA 1MMBA 2E3XA 3LE9A 2OW9A 2MLSA 4H3XA 2D1OA 5L79A 2TCLA 2MZEA 3OHLA 4GUYA 3P24A 3LUMA 4GQLA 1BUDA 1Y8JA 4AXQA 4H82A 4G9LA 3DL1A 2E2DA 4XBHA 2ERPA 2L0RA 4HX3A 1ZP5A 2JSDA 2DDFA 1UTZA 830CA 1GO7P 5D1SA 2YIGA 4R3VA 2OI0A 4G0DA 2A8HA 4WKEA 1D8FA 2W14A 1GXDA 2MZHA 2OXWA 1GE7A 2K9CA 4I35A 1EB6A 1PWVA 2DW0A 5B5PA 5D7WA 1RM8A 3DPFA 1KAPP 1UMSA 2AIGP 4H49A 1DTHA 2JT6A 3EWJA 1XURA 1IAEA 4IUWA 1K7QA 3UVCA 4H30A 1DMTA 1ZS0A 2O3EA 1BKCI 4PKRA 1YOUA 3RTTA 1CIZA 3K7LA 1XFYA 1GE6A 1WNIA 3LILA 3DWBA 1Y0VA 3WV1A 3TS4A 2DW2A 3HYGA 2FV5A 1D8MA 3B92A 1KUKA 2JT5A 4PKWA 1XFWA 4JQGA 3KEKA 1ZTQA 3LQBA 1R1HA 3NX7A 4PKQA 4L7AA 4XM6A 2POJA 2WO9A 1CAQA 3EDIA 3HDAP 1CXVA 2OXZA 3CKIA 1RMZA 1FBLA 1A85A 1O0QA 3EDGA 3LEAA 3V96B 2N8RA 3KMEA 1OM7A 3B8ZA 3KMCA 1R1IA 2OY2A 1Q3AA 3AIGA 3L0VA 3ZXHA 3DSLA 1HTDA 3I7GA 2KRJA 3AYKA 3F17A 4PKSA 1CGEA 3WV2A 3DTKA 5D2BA 5LABA 456CA 5CZMA 3O64A 3WV3A 1JKYA 4A3WA 3DTEA 4GR3A 2EROA 1SRPA 2JNPA 1K7GA 2J83A 4DD8A 5CUHA 2OY4A 1OO9A 1C7KA 2XS4A 4L63A 5I2ZA 1KUFA 2J0TA 1XFZA 4A7BA 1OM6A 2WOAA 3F1AA 4JP4A 4CTHA 2Y6CA 2Y6DA 4DV8A 3TVCA 2AYKA 5D1UA 3E8RA 1IAGA 1ZXVA 2OW1A 4ILWD 3LUNA 1JAPA 1MNCA 1JAQA 1XUCA 4Q1LA 2QPJA 3KWVC 1IACA 4IJOA 1YP1A 3ELMA 1OMJA 1D7XA 3TT4A 3USNA 3U1RA 1PWPA 4H76A 3EDHA 3HBUP 2W13A 1IADA 1PWWA 2X3CA 3Q2HA 4EFSA 3HBVP 3HB2P 2W15A 1BZSA 3L0TA 3KECA 4DPEA 1JAOA 1R55A 1SMPA 1YQYA 1MMRA 1KUGA 4L6TA 3VTGA 5JMYA 4PKVA 1G05A 3LJZA 4GR8A 4IN9A 2OXUA 4FU4A 2OW0A 5L7FA 5CXAA 5BOTA 4FXYP 2W0DA 1BQOA 3DTIA 4AYKA 3OHOA 1ROSA 1ZVXA 4XM7A 2ERQA 1QIAA 3LJGA 4I03A 4H1QA 1QICA 1FLSA 1HOVA 1YCMA 2MZIA 1BKCA 2RJQA 1I73A 1AYKA 2W12A 3SHIA 1PWUA 1G49A 1CQRA 5I4OA 3B2ZA 2DW1A 2PJTA 4AUOA 4AIGA 2X7MA 1CGFA 2I47A 3EDZA 3ZVSA 5BPAA 1BUVM 1XFUA 3LIRA 3DPEA 1KUHA 2YB9A 3LQ0A 3KHIA 1JANA 4H2EA 1HY7A 1USNA 1R1JA 4DF9A 1OM8A 5B5OA 1ASTA 1J7NA 5BOYA 5I0LA 2OVXA 1CK7A 4XM8A 2V4BA 3KEJA 3GBOA 3F16A 1HV5A 2OVZA 2MLRA 3VI1A 3P1VA 1L6JA 1KUIA 1GKCA 3MA2A 1G12A 1XFXA 1O0TA 3G42A 4WZVA 1C3IA 4ON1A 1KBCA 2Z2DA 3K7NA 3TSKA 1BKCE 2CLTA 4J4MA 2X3AA 5I12A 1BIWA 1CGLA 3DNGA 1Y93A 1B8YA 1QJJA 1S4BP 3ZUKA 4GF1A 5H8XA 2X3BA 4ZR5A 2RJPA 1SATA 4QKZA 3N2UA 1D5JA 4GR0A 4JA1A 2OZRA 1JH1A 3AYUA 1JIZA 5I43A 1SU3A 1ZXCA 2CKIA 1UEAA 1GKDA 2OW2A 1FM1A 3F18A 1AKLA 1BQQM 4H84A 1HFCA 3F15A 4WF6A 1XUDA 3LIKA 3N2VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GO8 P;  4WKI A;  1G4K A;  5D1T A;  1JJ9 A;  3I7I A;  3HY7 A;  4L19 A;  1I76 A;  4GWN A;  2XS3 A;  3F19 A;  5D3C A;  2HU6 A;  1JIW P;  1H71 P;  1UTT A;  4JPA A;  3RTS A;  2D1N A;  1SLM A;  4PKT A;  4FXQ A;  1JK3 A;  3EHX A;  4PKU A;  4FVL A;  3LGP A;  1ATL A;  1EAK A;  1BSW A;  2JIH A;  966C A;  2WO8 A;  3LK8 A;  3BA0 A;  2FV9 A;  1G9K A;  3O2X A;  1IAA A;  1GE5 A;  1MMQ A;  1Z3J A;  1C8T A;  1I1I P;  3LMC A;  1HFS A;  1ND1 A;  4JIJ A;  1R54 A;  1A86 A;  3KRY A;  4WK7 A;  3LJT A;  1QUA A;  3HDB A;  3Q2G A;  1OS9 A;  2DDY A;  1BM6 A;  1QIB A;  1K7I A;  2SRT A;  3HY9 A;  1XFV A;  1OS2 A;  1QJI A;  4HMA A;  3EHY A;  4GWM A;  2USN A;  1SLN A;  1PWQ A;  2O36 A;  2K2G A;  1MMP A;  1IAB A;  1UMT A;  5I3M A;  1EUB A;  3LKA A;  1B3D A;  1AF0 A;  4XCT A;  3G5C A;  1MMB A;  2E3X A;  3LE9 A;  2OW9 A;  2MLS A;  4H3X A;  2D1O A;  5L79 A;  2TCL A;  2MZE A;  3OHL A;  4GUY A;  3P24 A;  3LUM A;  4GQL A;  1BUD A;  1Y8J A;  4AXQ A;  4H82 A;  4G9L A;  3DL1 A;  2E2D A;  4XBH A;  2ERP A;  2L0R A;  4HX3 A;  1ZP5 A;  2JSD A;  2DDF A;  1UTZ A;  830C A;  1GO7 P;  5D1S A;  2YIG A;  4R3V A;  2OI0 A;  4G0D A;  2A8H A;  4WKE A;  1D8F A;  2W14 A;  1GXD A;  2MZH A;  2OXW A;  1GE7 A;  2K9C A;  4I35 A;  1EB6 A;  1PWV A;  2DW0 A;  5B5P A;  5D7W A;  1RM8 A;  3DPF A;  1KAP P;  1UMS A;  2AIG P;  4H49 A;  1DTH A;  2JT6 A;  3EWJ A;  1XUR A;  1IAE A;  4IUW A;  1K7Q A;  3UVC A;  4H30 A;  1DMT A;  1ZS0 A;  2O3E A;  1BKC I;  4PKR A;  1YOU A;  3RTT A;  1CIZ A;  3K7L A;  1XFY A;  1GE6 A;  1WNI A;  3LIL A;  3DWB A;  1Y0V A;  3WV1 A;  3TS4 A;  2DW2 A;  3HYG A;  2FV5 A;  1D8M A;  3B92 A;  1KUK A;  2JT5 A;  4PKW A;  1XFW A;  4JQG A;  3KEK A;  1ZTQ A;  3LQB A;  1R1H A;  3NX7 A;  4PKQ A;  4XM6 A;  2POJ A;  2WO9 A;  1CAQ A;  3EDI A;  3HDA P;  1CXV A;  2OXZ A;  3CKI A;  1RMZ A;  1FBL A;  1A85 A;  1O0Q A;  3EDG A;  3LEA A;  3V96 B;  2N8R A;  3KME A;  1OM7 A;  3B8Z A;  3KMC A;  1R1I A;  2OY2 A;  1Q3A A;  3AIG A;  3L0V A;  3ZXH A;  3DSL A;  1HTD A;  3I7G A;  2KRJ A;  3AYK A;  3F17 A;  4PKS A;  1CGE A;  3WV2 A;  5D2B A;  5LAB A;  456C A;  5CZM A;  3O64 A;  3WV3 A;  1JKY A;  4A3W A;  4GR3 A;  2ERO A;  1SRP A;  2JNP A;  1K7G A;  2J83 A;  4DD8 A;  5CUH A;  2OY4 A;  1OO9 A;  1C7K A;  2XS4 A;  4L63 A;  5I2Z A;  1KUF A;  2J0T A;  1XFZ A;  4A7B A;  1OM6 A;  2WOA A;  3F1A A;  4JP4 A;  4CTH A;  2Y6C A;  2Y6D A;  4DV8 A;  3TVC A;  2AYK A;  5D1U A;  3E8R A;  1IAG A;  1ZXV A;  2OW1 A;  4ILW D;  3LUN A;  1JAP A;  1MNC A;  1JAQ A;  1XUC A;  4Q1L A;  2QPJ A;  3KWV C;  1IAC A;  4IJO A;  1YP1 A;  3ELM A;  1OMJ A;  1D7X A;  3TT4 A;  3USN A;  3U1R A;  1PWP A;  4H76 A;  3EDH A;  3HBU P;  2W13 A;  1IAD A;  1PWW A;  2X3C A;  3Q2H A;  4EFS A;  3HBV P;  3HB2 P;  2W15 A;  1BZS A;  3L0T A;  3KEC A;  4DPE A;  1JAO A;  1R55 A;  1SMP A;  1YQY A;  1MMR A;  1KUG A;  4L6T A;  3VTG A;  5JMY A;  4PKV A;  1G05 A;  3LJZ A;  4GR8 A;  4IN9 A;  2OXU A;  4FU4 A;  2OW0 A;  5L7F A;  5CXA A;  5BOT A;  4FXY P;  2W0D A;  1BQO A;  4AYK A;  3OHO A;  1ROS A;  1ZVX A;  4XM7 A;  2ERQ A;  1QIA A;  3LJG A;  4I03 A;  4H1Q A;  1QIC A;  1FLS A;  1HOV A;  1YCM A;  2MZI A;  1BKC A;  2RJQ A;  1I73 A;  1AYK A;  2W12 A;  3SHI A;  1PWU A;  1G49 A;  1CQR A;  5I4O A;  3B2Z A;  2DW1 A;  2PJT A;  4AUO A;  4AIG A;  2X7M A;  1CGF A;  2I47 A;  3EDZ A;  3ZVS A;  5BPA A;  1BUV M;  1XFU A;  3LIR A;  3DPE A;  1KUH A;  2YB9 A;  3LQ0 A;  3KHI A;  1JAN A;  4H2E A;  1HY7 A;  1USN A;  1R1J A;  4DF9 A;  1OM8 A;  5B5O A;  1AST A;  1J7N A;  5BOY A;  5I0L A;  2OVX A;  1CK7 A;  4XM8 A;  2V4B A;  3KEJ A;  3GBO A;  3F16 A;  1HV5 A;  2OVZ A;  2MLR A;  3VI1 A;  3P1V A;  1L6J A;  1KUI A;  1GKC A;  3MA2 A;  1G12 A;  1XFX A;  1O0T A;  3G42 A;  4WZV A;  1C3I A;  4ON1 A;  1KBC A;  2Z2D A;  3K7N A;  3TSK A;  1BKC E;  2CLT A;  4J4M A;  2X3A A;  5I12 A;  1BIW A;  1CGL A;  3DNG A;  1Y93 A;  1B8Y A;  1QJJ A;  1S4B P;  3ZUK A;  4GF1 A;  5H8X A;  2X3B A;  4ZR5 A;  2RJP A;  1SAT A;  4QKZ A;  3N2U A;  1D5J A;  4GR0 A;  4JA1 A;  2OZR A;  1JH1 A;  3AYU A;  1JIZ A;  5I43 A;  1SU3 A;  1ZXC A;  2CKI A;  1UEA A;  1GKD A;  2OW2 A;  1FM1 A;  3F18 A;  1AKL A;  1BQQ M;  4H84 A;  1HFC A;  3F15 A;  4WF6 A;  1XUD A;  3LIK A;  3N2V A; 
#chains in the Genus database with same CATH topology
 1GO8 P;  4WKI A;  1G4K A;  5D1T A;  1JJ9 A;  3I7I A;  3HY7 A;  4L19 A;  1I76 A;  4GWN A;  2XS3 A;  3F19 A;  5D3C A;  2HU6 A;  1JIW P;  1H71 P;  1UTT A;  4JPA A;  3RTS A;  2D1N A;  1SLM A;  4PKT A;  4FXQ A;  1JK3 A;  3EHX A;  4PKU A;  4FVL A;  3LGP A;  1ATL A;  1EAK A;  1BSW A;  2JIH A;  966C A;  2WO8 A;  3LK8 A;  3BA0 A;  2FV9 A;  1G9K A;  3O2X A;  1IAA A;  1GE5 A;  1MMQ A;  1Z3J A;  1C8T A;  1I1I P;  3LMC A;  1HFS A;  1ND1 A;  4JIJ A;  1R54 A;  1A86 A;  3KRY A;  4WK7 A;  3LJT A;  1QUA A;  3HDB A;  3Q2G A;  1OS9 A;  2DDY A;  1BM6 A;  1QIB A;  1K7I A;  2SRT A;  3HY9 A;  1XFV A;  1OS2 A;  1QJI A;  2YUF A;  4HMA A;  3EHY A;  4GWM A;  2USN A;  1SLN A;  1PWQ A;  2O36 A;  2K2G A;  1MMP A;  1IAB A;  1UMT A;  5I3M A;  1EUB A;  3LKA A;  1B3D A;  1AF0 A;  4XCT A;  3G5C A;  1MMB A;  2E3X A;  3LE9 A;  2OW9 A;  2MLS A;  4H3X A;  2D1O A;  5L79 A;  2TCL A;  2MZE A;  3OHL A;  4GUY A;  3P24 A;  3LUM A;  4GQL A;  1BUD A;  1Y8J A;  4AXQ A;  4H82 A;  4G9L A;  3DL1 A;  2E2D A;  4XBH A;  2ERP A;  2L0R A;  4HX3 A;  1ZP5 A;  2JSD A;  2DDF A;  1UTZ A;  830C A;  1GO7 P;  5D1S A;  2YIG A;  4R3V A;  2OI0 A;  4G0D A;  2A8H A;  4WKE A;  1D8F A;  2W14 A;  1GXD A;  2MZH A;  2OXW A;  1GE7 A;  2K9C A;  4I35 A;  1XM5 A;  1EB6 A;  1PWV A;  2DW0 A;  5B5P A;  5D7W A;  1RM8 A;  3DPF A;  1KAP P;  1UMS A;  2AIG P;  4H49 A;  1DTH A;  2JT6 A;  3EWJ A;  1XUR A;  1IAE A;  4IUW A;  1K7Q A;  3UVC A;  4H30 A;  1DMT A;  1ZS0 A;  2O3E A;  1BKC I;  4PKR A;  1YOU A;  3RTT A;  1CIZ A;  3K7L A;  1XFY A;  1GE6 A;  1WNI A;  3LIL A;  3DWB A;  1Y0V A;  3WV1 A;  3TS4 A;  2DW2 A;  3HYG A;  2FV5 A;  1D8M A;  3B92 A;  1KUK A;  2JT5 A;  4PKW A;  1XFW A;  4JQG A;  3KEK A;  1ZTQ A;  3LQB A;  1R1H A;  3NX7 A;  4PKQ A;  4L7A A;  4XM6 A;  2POJ A;  2WO9 A;  1CAQ A;  3EDI A;  3HDA P;  1CXV A;  2OXZ A;  3CKI A;  1RMZ A;  1FBL A;  1A85 A;  1O0Q A;  3EDG A;  3LEA A;  3V96 B;  2N8R A;  3KME A;  1OM7 A;  3B8Z A;  3KMC A;  1R1I A;  2OY2 A;  1Q3A A;  3AIG A;  3L0V A;  3ZXH A;  3DSL A;  1HTD A;  3I7G A;  2KRJ A;  3AYK A;  3F17 A;  4PKS A;  1CGE A;  3WV2 A;  3DTK A;  5D2B A;  5LAB A;  456C A;  5CZM A;  3O64 A;  3WV3 A;  1JKY A;  4A3W A;  3DTE A;  4GR3 A;  2ERO A;  1SRP A;  2JNP A;  1K7G A;  2J83 A;  4DD8 A;  5CUH A;  2OY4 A;  1OO9 A;  1C7K A;  2XS4 A;  4L63 A;  5I2Z A;  1KUF A;  2J0T A;  1XFZ A;  4A7B A;  1OM6 A;  2WOA A;  3F1A A;  4JP4 A;  4CTH A;  2Y6C A;  2Y6D A;  4DV8 A;  3TVC A;  2AYK A;  5D1U A;  3E8R A;  1IAG A;  1ZXV A;  2OW1 A;  4ILW D;  3LUN A;  1JAP A;  1MNC A;  1JAQ A;  1XUC A;  4Q1L A;  2QPJ A;  3KWV C;  1IAC A;  4IJO A;  1YP1 A;  3ELM A;  1OMJ A;  1D7X A;  3TT4 A;  3USN A;  3U1R A;  1PWP A;  4H76 A;  3EDH A;  3HBU P;  2W13 A;  1IAD A;  1PWW A;  2X3C A;  3Q2H A;  4EFS A;  3HBV P;  3HB2 P;  2W15 A;  1BZS A;  3L0T A;  3KEC A;  4DPE A;  1JAO A;  1R55 A;  1SMP A;  1YQY A;  1MMR A;  1KUG A;  4L6T A;  1OZ9 A;  3VTG A;  5JMY A;  4PKV A;  1G05 A;  3LJZ A;  4GR8 A;  4IN9 A;  2OXU A;  4FU4 A;  2OW0 A;  5L7F A;  5CXA A;  5BOT A;  4FXY P;  2W0D A;  1BQO A;  3DTI A;  4AYK A;  3OHO A;  1ROS A;  1ZVX A;  4XM7 A;  2ERQ A;  1QIA A;  3LJG A;  4I03 A;  4H1Q A;  1QIC A;  1FLS A;  1HOV A;  1YCM A;  2MZI A;  1BKC A;  2RJQ A;  1I73 A;  1AYK A;  2W12 A;  3SHI A;  1PWU A;  1G49 A;  1CQR A;  5I4O A;  3B2Z A;  2DW1 A;  2PJT A;  4AUO A;  4AIG A;  2X7M A;  1CGF A;  2I47 A;  3EDZ A;  3ZVS A;  5BPA A;  1BUV M;  1XFU A;  3LIR A;  3DPE A;  1KUH A;  2YB9 A;  3LQ0 A;  3KHI A;  1JAN A;  4H2E A;  1HY7 A;  1USN A;  1R1J A;  4DF9 A;  1OM8 A;  5B5O A;  1AST A;  1J7N A;  5BOY A;  5I0L A;  2OVX A;  1CK7 A;  1XAX A;  4XM8 A;  2V4B A;  3KEJ A;  3GBO A;  3F16 A;  1HV5 A;  2OVZ A;  2MLR A;  3VI1 A;  3P1V A;  1L6J A;  1KUI A;  1GKC A;  3MA2 A;  1G12 A;  1XFX A;  1O0T A;  3G42 A;  4WZV A;  1C3I A;  4ON1 A;  1KBC A;  2Z2D A;  3K7N A;  3TSK A;  1BKC E;  2CLT A;  1TVI A;  4J4M A;  2X3A A;  5I12 A;  1BIW A;  1CGL A;  3DNG A;  1Y93 A;  1B8Y A;  1QJJ A;  1S4B P;  3ZUK A;  4GF1 A;  5H8X A;  2X3B A;  4ZR5 A;  2RJP A;  1SAT A;  4QKZ A;  3N2U A;  1D5J A;  4GR0 A;  4JA1 A;  2OZR A;  1JH1 A;  3AYU A;  1JIZ A;  5I43 A;  1SU3 A;  1ZXC A;  2CKI A;  1UEA A;  1GKD A;  2OW2 A;  1FM1 A;  3F18 A;  1AKL A;  1BQQ M;  4H84 A;  1HFC A;  3F15 A;  4WF6 A;  1XUD A;  3LIK A;  3N2V A; 
#chains in the Genus database with same CATH homology
 1GO8 P;  4WKI A;  1G4K A;  5D1T A;  1JJ9 A;  3I7I A;  3HY7 A;  4L19 A;  1I76 A;  4GWN A;  2XS3 A;  3F19 A;  5D3C A;  2HU6 A;  1JIW P;  1H71 P;  1UTT A;  4JPA A;  3RTS A;  2D1N A;  1SLM A;  4PKT A;  4FXQ A;  1JK3 A;  3EHX A;  4PKU A;  4FVL A;  3LGP A;  1ATL A;  1EAK A;  1BSW A;  2JIH A;  966C A;  2WO8 A;  3LK8 A;  3BA0 A;  2FV9 A;  1G9K A;  3O2X A;  1IAA A;  1GE5 A;  1MMQ A;  1Z3J A;  1C8T A;  1I1I P;  3LMC A;  1HFS A;  1ND1 A;  4JIJ A;  1R54 A;  1A86 A;  3KRY A;  4WK7 A;  3LJT A;  1QUA A;  3HDB A;  3Q2G A;  1OS9 A;  2DDY A;  1BM6 A;  1QIB A;  1K7I A;  2SRT A;  3HY9 A;  1XFV A;  1OS2 A;  1QJI A;  2YUF A;  4HMA A;  3EHY A;  4GWM A;  2USN A;  1SLN A;  1PWQ A;  2O36 A;  2K2G A;  1MMP A;  1IAB A;  1UMT A;  5I3M A;  1EUB A;  3LKA A;  1B3D A;  1AF0 A;  4XCT A;  3G5C A;  1MMB A;  2E3X A;  3LE9 A;  2OW9 A;  2MLS A;  4H3X A;  2D1O A;  5L79 A;  2TCL A;  2MZE A;  3OHL A;  4GUY A;  3P24 A;  3LUM A;  4GQL A;  1BUD A;  1Y8J A;  4AXQ A;  4H82 A;  4G9L A;  3DL1 A;  2E2D A;  4XBH A;  2ERP A;  2L0R A;  4HX3 A;  1ZP5 A;  2JSD A;  2DDF A;  1UTZ A;  830C A;  1GO7 P;  5D1S A;  2YIG A;  4R3V A;  2OI0 A;  4G0D A;  2A8H A;  4WKE A;  1D8F A;  2W14 A;  1GXD A;  2MZH A;  2OXW A;  1GE7 A;  2K9C A;  4I35 A;  1EB6 A;  1PWV A;  2DW0 A;  5B5P A;  5D7W A;  1RM8 A;  3DPF A;  1KAP P;  1UMS A;  2AIG P;  4H49 A;  1DTH A;  2JT6 A;  3EWJ A;  1XUR A;  1IAE A;  4IUW A;  1K7Q A;  3UVC A;  4H30 A;  1DMT A;  1ZS0 A;  2O3E A;  1BKC I;  4PKR A;  1YOU A;  3RTT A;  1CIZ A;  3K7L A;  1XFY A;  1GE6 A;  1WNI A;  3LIL A;  3DWB A;  1Y0V A;  3WV1 A;  3TS4 A;  2DW2 A;  3HYG A;  2FV5 A;  1D8M A;  3B92 A;  1KUK A;  2JT5 A;  4PKW A;  1XFW A;  4JQG A;  3KEK A;  1ZTQ A;  3LQB A;  1R1H A;  3NX7 A;  4PKQ A;  4L7A A;  4XM6 A;  2POJ A;  2WO9 A;  1CAQ A;  3EDI A;  3HDA P;  1CXV A;  2OXZ A;  3CKI A;  1RMZ A;  1FBL A;  1A85 A;  1O0Q A;  3EDG A;  3LEA A;  3V96 B;  2N8R A;  3KME A;  1OM7 A;  3B8Z A;  3KMC A;  1R1I A;  2OY2 A;  1Q3A A;  3AIG A;  3L0V A;  3ZXH A;  3DSL A;  1HTD A;  3I7G A;  2KRJ A;  3AYK A;  3F17 A;  4PKS A;  1CGE A;  3WV2 A;  3DTK A;  5D2B A;  5LAB A;  456C A;  5CZM A;  3O64 A;  3WV3 A;  1JKY A;  4A3W A;  3DTE A;  4GR3 A;  2ERO A;  1SRP A;  2JNP A;  1K7G A;  2J83 A;  4DD8 A;  5CUH A;  2OY4 A;  1OO9 A;  1C7K A;  2XS4 A;  4L63 A;  5I2Z A;  1KUF A;  2J0T A;  1XFZ A;  4A7B A;  1OM6 A;  2WOA A;  3F1A A;  4JP4 A;  4CTH A;  2Y6C A;  2Y6D A;  4DV8 A;  3TVC A;  2AYK A;  5D1U A;  3E8R A;  1IAG A;  1ZXV A;  2OW1 A;  4ILW D;  3LUN A;  1JAP A;  1MNC A;  1JAQ A;  1XUC A;  4Q1L A;  2QPJ A;  3KWV C;  1IAC A;  4IJO A;  1YP1 A;  3ELM A;  1OMJ A;  1D7X A;  3TT4 A;  3USN A;  3U1R A;  1PWP A;  4H76 A;  3EDH A;  3HBU P;  2W13 A;  1IAD A;  1PWW A;  2X3C A;  3Q2H A;  4EFS A;  3HBV P;  3HB2 P;  2W15 A;  1BZS A;  3L0T A;  3KEC A;  4DPE A;  1JAO A;  1R55 A;  1SMP A;  1YQY A;  1MMR A;  1KUG A;  4L6T A;  3VTG A;  5JMY A;  4PKV A;  1G05 A;  3LJZ A;  4GR8 A;  4IN9 A;  2OXU A;  4FU4 A;  2OW0 A;  5L7F A;  5CXA A;  5BOT A;  4FXY P;  2W0D A;  1BQO A;  3DTI A;  4AYK A;  3OHO A;  1ROS A;  1ZVX A;  4XM7 A;  2ERQ A;  1QIA A;  3LJG A;  4I03 A;  4H1Q A;  1QIC A;  1FLS A;  1HOV A;  1YCM A;  2MZI A;  1BKC A;  2RJQ A;  1I73 A;  1AYK A;  2W12 A;  3SHI A;  1PWU A;  1G49 A;  1CQR A;  5I4O A;  3B2Z A;  2DW1 A;  2PJT A;  4AUO A;  4AIG A;  2X7M A;  1CGF A;  2I47 A;  3EDZ A;  3ZVS A;  5BPA A;  1BUV M;  1XFU A;  3LIR A;  3DPE A;  1KUH A;  2YB9 A;  3LQ0 A;  3KHI A;  1JAN A;  4H2E A;  1HY7 A;  1USN A;  1R1J A;  4DF9 A;  1OM8 A;  5B5O A;  1AST A;  1J7N A;  5BOY A;  5I0L A;  2OVX A;  1CK7 A;  4XM8 A;  2V4B A;  3KEJ A;  3GBO A;  3F16 A;  1HV5 A;  2OVZ A;  2MLR A;  3VI1 A;  3P1V A;  1L6J A;  1KUI A;  1GKC A;  3MA2 A;  1G12 A;  1XFX A;  1O0T A;  3G42 A;  4WZV A;  1C3I A;  4ON1 A;  1KBC A;  2Z2D A;  3K7N A;  3TSK A;  1BKC E;  2CLT A;  4J4M A;  2X3A A;  5I12 A;  1BIW A;  1CGL A;  3DNG A;  1Y93 A;  1B8Y A;  1QJJ A;  1S4B P;  3ZUK A;  4GF1 A;  5H8X A;  2X3B A;  4ZR5 A;  2RJP A;  1SAT A;  4QKZ A;  3N2U A;  1D5J A;  4GR0 A;  4JA1 A;  2OZR A;  1JH1 A;  3AYU A;  1JIZ A;  5I43 A;  1SU3 A;  1ZXC A;  2CKI A;  1UEA A;  1GKD A;  2OW2 A;  1FM1 A;  3F18 A;  1AKL A;  1BQQ M;  4H84 A;  1HFC A;  3F15 A;  4WF6 A;  1XUD A;  3LIK A;  3N2V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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