2W0DA

Does a fast nuclear magnetic resonance spectroscopy- and x-ray crystallography hybrid approach provide reliable structural information of ligand-protein complexes? a case study of metalloproteinases.
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
158
structure length
158
Chain Sequence
GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDFHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHAIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Does a Fast Nuclear Magnetic Resonance Spectroscopy- and X-Ray Crystallography Hybrid Approach Provide Reliable Structural Information of Ligand-Protein Complexes? a Case Study of Metalloproteinases.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords MACROPHAGE METALLOELASTASE
total genus 47
structure length 158
sequence length 158
chains with identical sequence B, C, D
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2008-08-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 2w0dA00
1SU3A 3U1RA 3LQ0A 2JT5A 1AYKA 2V4BA 4PKQA 1KAPP 4AIGA 456CA 1IADA 4XCTA 2DDFA 3LJZA 966CA 4J4MA 1AF0A 3LGPA 4H84A 2ERPA 2O36A 5I0LA 3F18A 5LABA 2JSDA 1ZTQA 1UTZA 1PWUA 1G05A 4Q1LA 5H8XA 2OW9A 3HBVP 2OXUA 3KHIA 3I7IA 1A85A 2JIHA 1FBLA 5D1UA 1S4BP 2E3XA 4JIJA 3O64A 1BQQM 3G5CA 1B8YA 4FU4A 3P24A 1MNCA 4XBHA 1SATA 3KEKA 1ROSA 3LK8A 3WV3A 4I35A 1QICA 5D7WA 1QIBA 2POJA 4AUOA 4DF9A 3LE9A 4DV8A 2X3CA 4L6TA 1ZXCA 4GF1A 1CK7A 1BKCE 1ASTA 1FLSA 2A8HA 1XUDA 1JIZA 4PKSA 2DDYA 4GWNA 1ZS0A 1GO7P 3EDZA 1KUIA 1PWWA 1ZXVA 2TCLA 2FV9A 4G0DA 4XM7A 4JPAA 1D8FA 2QPJA 4H1QA 1UMSA 1PWPA 4HMAA 3LUNA 2MZHA 3LJGA 3DPFA 1IAAA 1J7NA 3WV2A 1CGLA 2WO8A 2J83A 2OW2A 1SRPA 4FXQA 1HFSA 4AXQA 3AYKA 1C8TA 1DTHA 5JMYA 1K7GA 5CXAA 1OM6A 2EROA 1MMPA 5CUHA 3F1AA 5I3MA 2DW0A 1G4KA 2JNPA 3LUMA 2WOAA 5B5PA 3TS4A 2OVXA 1GXDA 1BUVM 1L6JA 2PJTA 1IACA 1JAQA 1HTDA 3KEJA 4GUYA 1G9KA 3TT4A 2DW2A 1C3IA 4I03A 1G12A 3ZXHA 5BPAA 1BQOA 4PKRA 1AKLA 4A3WA 5CZMA 1EB6A 1JAOA 1ATLA 3RTSA 2OW0A 1YOUA 4IN9A 1A86A 1OS2A 1O0TA 1EUBA 2OY4A 1JAPA 3HB2P 1RMZA 3SHIA 1I1IP 1BIWA 5BOYA 1GE7A 1GO8P 1G49A 5D2BA 1MMBA 2AIGP 2XS3A 3KMCA 1OS9A 2CLTA 3EDIA 1Q3AA 4IUWA 3KMEA 2DW1A 1YQYA 1XFXA 1OO9A 1Y93A 1XFWA 4PKWA 1R55A 1UEAA 2W13A 3LMCA 3F19A 2N8RA 2X7MA 4PKTA 1UMTA 1ZVXA 3V96B 1QUAA 1CAQA 2MLSA 3OHOA 1EAKA 3HDBA 2FV5A 1OM7A 2MLRA 2W0DA 1ND1A 1DMTA 830CA 5L7FA 5I2ZA 5B5OA 1IAEA 3L0TA 1R54A 4CTHA 2K2GA 5L79A 3K7NA 1YCMA 3LQBA 1JIWP 3HY9A 3EDGA 4GWMA 1GKCA 3EHXA 4JP4A 5I4OA 3ZUKA 1HFCA 1CGFA 4WZVA 3Q2HA 3USNA 3F16A 2RJQA 1CIZA 3HDAP 1KBCA 3LKAA 3TSKA 1Z3JA 3UVCA 3EDHA 4H49A 2Z2DA 2D1OA 2YIGA 4DD8A 1QJIA 1C7KA 1K7QA 4H30A 1XFVA 1KUHA 1Y8JA 3DPEA 1MMRA 2CKIA 1JK3A 2Y6DA 1SLNA 4GR0A 1KUFA 2WO9A 4WK7A 1H71P 1PWQA 4WKEA 2XS4A 1HY7A 3TVCA 3E8RA 3BA0A 1Y0VA 1OMJA 3GBOA 4HX3A 3N2UA 1XFZA 2OXWA 2KRJA 3WV1A 4G9LA 4WF6A 3RTTA 1GE5A 4PKUA 1BUDA 2W15A 1D7XA 1CGEA 1PWVA 4L63A 1JKYA 2OVZA 1XUCA 2D1NA 4H2EA 3K7LA 2ERQA 2OI0A 2OZRA 4GR8A 3VTGA 3CKIA 2USNA 3EHYA 3F17A 4IJOA 1SLMA 1XFUA 1USNA 2MZEA 3EWJA 2OXZA 4DPEA 1XURA 1GE6A 3DWBA 1BZSA 3OHLA 1D8MA 3ZVSA 4QKZA 2AYKA 4GR3A 4WKIA 2I47A 1FM1A 3LJTA 4XM6A 4JA1A 3DNGA 3I7GA 4H3XA 1JANA 1SMPA 3DSLA 4H76A 1R1JA 5I12A 3Q2GA 1R1HA 3ELMA 3N2VA 1BM6A 3HY7A 1HOVA 2OY2A 1O0QA 3L0VA 4ON1A 5D1SA 4AYKA 1IAGA 1YP1A 3HYGA 1WNIA 3DL1A 3KECA 2Y6CA 3P1VA 3B2ZA 1CXVA 4A7BA 2HU6A 1BKCA 4FVLA 3AYUA 2K9CA 2X3BA 5D3CA 3KWVC 5BOTA 2W14A 4ZR5A 3B8ZA 4XM8A 2W12A 4PKVA 1KUGA 3LILA 1K7IA 1IABA 3MA2A 2L0RA 1UTTA 2O3EA 3LEAA 1KUKA 1BSWA 2JT6A 3NX7A 5D1TA 3LIKA 1D5JA 3HBUP 1RM8A 1CQRA 3G42A 1JJ9A 1I73A 1GKDA 3O2XA 5I43A 2SRTA 3VI1A 1OM8A 4FXYP 4H82A 3LIRA 1XFYA 2X3AA 4JQGA 3KRYA 2OW1A 1B3DA 1I76A 3B92A 1QJJA 1MMQA 3AIGA 1QIAA 1JH1A 4ILWD 2RJPA 4GQLA 4EFSA 4R3VA 1ZP5A 1HV5A 2E2DA 2MZIA 2J0TA 1BKCI 2YB9A 4L19A 1R1IA 3F15A
chains in the Genus database with same CATH superfamily
1SU3A 3U1RA 3LQ0A 1XAXA 3DTKA 2JT5A 1AYKA 2V4BA 4PKQA 1KAPP 4AIGA 456CA 1IADA 4XCTA 2DDFA 3LJZA 966CA 4J4MA 1AF0A 3LGPA 4H84A 2ERPA 2O36A 5I0LA 3F18A 5LABA 2JSDA 1ZTQA 1UTZA 1PWUA 1G05A 4Q1LA 5H8XA 2OW9A 3HBVP 2OXUA 3KHIA 3I7IA 1A85A 2JIHA 1FBLA 5D1UA 1S4BP 2E3XA 4JIJA 3O64A 1BQQM 3G5CA 1B8YA 4FU4A 3P24A 1MNCA 4XBHA 1SATA 3KEKA 1ROSA 3LK8A 3WV3A 4I35A 1QICA 5D7WA 3DTEA 4L7AA 1QIBA 2POJA 4AUOA 4DF9A 3LE9A 4DV8A 2X3CA 4L6TA 1ZXCA 2YUFA 4GF1A 1CK7A 1BKCE 1ASTA 1FLSA 2A8HA 1XUDA 1JIZA 4PKSA 2DDYA 4GWNA 1ZS0A 1GO7P 3EDZA 1KUIA 1PWWA 1ZXVA 2TCLA 2FV9A 4G0DA 4XM7A 4JPAA 1D8FA 2QPJA 4H1QA 1UMSA 1PWPA 4HMAA 3LUNA 2MZHA 3LJGA 3DPFA 1IAAA 1J7NA 3WV2A 1TVIA 1CGLA 2WO8A 2J83A 2OW2A 1SRPA 4FXQA 1HFSA 4AXQA 3AYKA 1C8TA 1DTHA 5JMYA 1K7GA 5CXAA 1OM6A 2EROA 1MMPA 5CUHA 3F1AA 5I3MA 2DW0A 1G4KA 2JNPA 3LUMA 2WOAA 5B5PA 3TS4A 2OVXA 1GXDA 1BUVM 1L6JA 2PJTA 1IACA 1JAQA 1HTDA 3KEJA 4GUYA 1G9KA 3TT4A 2DW2A 1C3IA 4I03A 1G12A 3ZXHA 5BPAA 1BQOA 4PKRA 1AKLA 4A3WA 5CZMA 1EB6A 1JAOA 1ATLA 3RTSA 2OW0A 1YOUA 4IN9A 1A86A 1OS2A 1O0TA 1EUBA 2OY4A 1JAPA 3HB2P 1RMZA 3SHIA 1I1IP 1BIWA 5BOYA 1GE7A 1GO8P 1G49A 5D2BA 1MMBA 2AIGP 2XS3A 3KMCA 1OS9A 2CLTA 3EDIA 1Q3AA 4IUWA 3KMEA 2DW1A 1YQYA 1XFXA 1OO9A 1Y93A 1XFWA 4PKWA 1R55A 1UEAA 2W13A 3LMCA 3F19A 2N8RA 2X7MA 4PKTA 1UMTA 1ZVXA 3V96B 1QUAA 1CAQA 2MLSA 3OHOA 1EAKA 3HDBA 2FV5A 1OM7A 2MLRA 2W0DA 1ND1A 1DMTA 830CA 5L7FA 5I2ZA 5B5OA 1IAEA 3L0TA 1R54A 4CTHA 2K2GA 5L79A 3K7NA 1YCMA 3LQBA 1JIWP 3HY9A 3EDGA 4GWMA 1GKCA 3EHXA 4JP4A 5I4OA 3ZUKA 1HFCA 1CGFA 4WZVA 3Q2HA 3USNA 3F16A 2RJQA 1CIZA 3HDAP 1KBCA 3LKAA 3TSKA 1Z3JA 3UVCA 3EDHA 4H49A 2Z2DA 2D1OA 2YIGA 4DD8A 1QJIA 1C7KA 1K7QA 4H30A 1XFVA 1KUHA 1Y8JA 3DPEA 1MMRA 2CKIA 1JK3A 2Y6DA 1SLNA 4GR0A 1KUFA 2WO9A 4WK7A 1H71P 1PWQA 4WKEA 2XS4A 1HY7A 3TVCA 3E8RA 3BA0A 1Y0VA 1OMJA 3GBOA 4HX3A 3N2UA 1XFZA 2OXWA 2KRJA 3WV1A 4G9LA 4WF6A 3RTTA 1GE5A 4PKUA 1BUDA 2W15A 1D7XA 1OZ9A 1CGEA 1PWVA 3DTIA 4L63A 1JKYA 2OVZA 1XUCA 2D1NA 4H2EA 3K7LA 2ERQA 2OI0A 2OZRA 4GR8A 3VTGA 3CKIA 2USNA 3EHYA 3F17A 4IJOA 1SLMA 1XFUA 1USNA 2MZEA 3EWJA 2OXZA 4DPEA 1XURA 1GE6A 3DWBA 1BZSA 3OHLA 1D8MA 3ZVSA 4QKZA 2AYKA 4GR3A 4WKIA 2I47A 1FM1A 3LJTA 4XM6A 4JA1A 3DNGA 3I7GA 4H3XA 1JANA 1SMPA 3DSLA 4H76A 1R1JA 5I12A 3Q2GA 1R1HA 3ELMA 3N2VA 1BM6A 3HY7A 1HOVA 2OY2A 1O0QA 3L0VA 4ON1A 5D1SA 4AYKA 1IAGA 1YP1A 3HYGA 1WNIA 3DL1A 3KECA 2Y6CA 3P1VA 3B2ZA 1CXVA 4A7BA 2HU6A 1BKCA 4FVLA 3AYUA 2K9CA 2X3BA 5D3CA 3KWVC 5BOTA 2W14A 4ZR5A 3B8ZA 4XM8A 2W12A 4PKVA 1KUGA 3LILA 1K7IA 1IABA 3MA2A 2L0RA 1UTTA 2O3EA 3LEAA 1KUKA 1BSWA 2JT6A 3NX7A 5D1TA 3LIKA 1D5JA 3HBUP 1RM8A 1CQRA 3G42A 1JJ9A 1I73A 1GKDA 3O2XA 5I43A 2SRTA 3VI1A 1OM8A 4FXYP 4H82A 3LIRA 1XFYA 2X3AA 4JQGA 3KRYA 2OW1A 1B3DA 1I76A 3B92A 1QJJA 1MMQA 3AIGA 1QIAA 1JH1A 4ILWD 2RJPA 1XM5A 4GQLA 4EFSA 4R3VA 1ZP5A 1HV5A 2E2DA 2MZIA 2J0TA 1BKCI 2YB9A 4L19A 1R1IA 3F15A
chains in the Genus database with same CATH topology
1SU3A 3U1RA 3LQ0A 3DTKA 2JT5A 1AYKA 2V4BA 4PKQA 1KAPP 4AIGA 456CA 1IADA 4XCTA 2DDFA 3LJZA 966CA 4J4MA 1AF0A 3LGPA 4H84A 2ERPA 2O36A 5I0LA 3F18A 5LABA 2JSDA 1ZTQA 1UTZA 1PWUA 1G05A 4Q1LA 5H8XA 2OW9A 3HBVP 2OXUA 3KHIA 3I7IA 1A85A 2JIHA 1FBLA 5D1UA 1S4BP 2E3XA 4JIJA 3O64A 1BQQM 3G5CA 1B8YA 4FU4A 3P24A 1MNCA 4XBHA 1SATA 3KEKA 1ROSA 3LK8A 3WV3A 4I35A 1QICA 5D7WA 3DTEA 4L7AA 1QIBA 2POJA 4AUOA 4DF9A 3LE9A 4DV8A 2X3CA 4L6TA 1ZXCA 2YUFA 4GF1A 1CK7A 1BKCE 1ASTA 1FLSA 2A8HA 1XUDA 1JIZA 4PKSA 2DDYA 4GWNA 1ZS0A 1GO7P 3EDZA 1KUIA 1PWWA 1ZXVA 2TCLA 2FV9A 4G0DA 4XM7A 4JPAA 1D8FA 2QPJA 4H1QA 1UMSA 1PWPA 4HMAA 3LUNA 2MZHA 3LJGA 3DPFA 1IAAA 1J7NA 3WV2A 1CGLA 2WO8A 2J83A 2OW2A 1SRPA 4FXQA 1HFSA 4AXQA 3AYKA 1C8TA 1DTHA 5JMYA 1K7GA 5CXAA 1OM6A 2EROA 1MMPA 5CUHA 3F1AA 5I3MA 2DW0A 1G4KA 2JNPA 3LUMA 2WOAA 5B5PA 3TS4A 2OVXA 1GXDA 1BUVM 1L6JA 2PJTA 1IACA 1JAQA 1HTDA 3KEJA 4GUYA 1G9KA 3TT4A 2DW2A 1C3IA 4I03A 1G12A 3ZXHA 5BPAA 1BQOA 4PKRA 1AKLA 4A3WA 5CZMA 1EB6A 1JAOA 1ATLA 3RTSA 2OW0A 1YOUA 4IN9A 1A86A 1OS2A 1O0TA 1EUBA 2OY4A 1JAPA 3HB2P 1RMZA 3SHIA 1I1IP 1BIWA 5BOYA 1GE7A 1GO8P 1G49A 5D2BA 1MMBA 2AIGP 2XS3A 3KMCA 1OS9A 2CLTA 3EDIA 1Q3AA 4IUWA 3KMEA 2DW1A 1YQYA 1XFXA 1OO9A 1Y93A 1XFWA 4PKWA 1R55A 1UEAA 2W13A 3LMCA 3F19A 2N8RA 2X7MA 4PKTA 1UMTA 1ZVXA 3V96B 1QUAA 1CAQA 2MLSA 3OHOA 1EAKA 3HDBA 2FV5A 1OM7A 2MLRA 2W0DA 1ND1A 1DMTA 830CA 5L7FA 5I2ZA 5B5OA 1IAEA 3L0TA 1R54A 4CTHA 2K2GA 5L79A 3K7NA 1YCMA 3LQBA 1JIWP 3HY9A 3EDGA 4GWMA 1GKCA 3EHXA 4JP4A 5I4OA 3ZUKA 1HFCA 1CGFA 4WZVA 3Q2HA 3USNA 3F16A 2RJQA 1CIZA 3HDAP 1KBCA 3LKAA 3TSKA 1Z3JA 3UVCA 3EDHA 4H49A 2Z2DA 2D1OA 2YIGA 4DD8A 1QJIA 1C7KA 1K7QA 4H30A 1XFVA 1KUHA 1Y8JA 3DPEA 1MMRA 2CKIA 1JK3A 2Y6DA 1SLNA 4GR0A 1KUFA 2WO9A 4WK7A 1H71P 1PWQA 4WKEA 2XS4A 1HY7A 3TVCA 3E8RA 3BA0A 1Y0VA 1OMJA 3GBOA 4HX3A 3N2UA 1XFZA 2OXWA 2KRJA 3WV1A 4G9LA 4WF6A 3RTTA 1GE5A 4PKUA 1BUDA 2W15A 1D7XA 1CGEA 1PWVA 3DTIA 4L63A 1JKYA 2OVZA 1XUCA 2D1NA 4H2EA 3K7LA 2ERQA 2OI0A 2OZRA 4GR8A 3VTGA 3CKIA 2USNA 3EHYA 3F17A 4IJOA 1SLMA 1XFUA 1USNA 2MZEA 3EWJA 2OXZA 4DPEA 1XURA 1GE6A 3DWBA 1BZSA 3OHLA 1D8MA 3ZVSA 4QKZA 2AYKA 4GR3A 4WKIA 2I47A 1FM1A 3LJTA 4XM6A 4JA1A 3DNGA 3I7GA 4H3XA 1JANA 1SMPA 3DSLA 4H76A 1R1JA 5I12A 3Q2GA 1R1HA 3ELMA 3N2VA 1BM6A 3HY7A 1HOVA 2OY2A 1O0QA 3L0VA 4ON1A 5D1SA 4AYKA 1IAGA 1YP1A 3HYGA 1WNIA 3DL1A 3KECA 2Y6CA 3P1VA 3B2ZA 1CXVA 4A7BA 2HU6A 1BKCA 4FVLA 3AYUA 2K9CA 2X3BA 5D3CA 3KWVC 5BOTA 2W14A 4ZR5A 3B8ZA 4XM8A 2W12A 4PKVA 1KUGA 3LILA 1K7IA 1IABA 3MA2A 2L0RA 1UTTA 2O3EA 3LEAA 1KUKA 1BSWA 2JT6A 3NX7A 5D1TA 3LIKA 1D5JA 3HBUP 1RM8A 1CQRA 3G42A 1JJ9A 1I73A 1GKDA 3O2XA 5I43A 2SRTA 3VI1A 1OM8A 4FXYP 4H82A 3LIRA 1XFYA 2X3AA 4JQGA 3KRYA 2OW1A 1B3DA 1I76A 3B92A 1QJJA 1MMQA 3AIGA 1QIAA 1JH1A 4ILWD 2RJPA 4GQLA 4EFSA 4R3VA 1ZP5A 1HV5A 2E2DA 2MZIA 2J0TA 1BKCI 2YB9A 4L19A 1R1IA 3F15A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SU3 A;  3U1R A;  3LQ0 A;  2JT5 A;  1AYK A;  2V4B A;  4PKQ A;  1KAP P;  4AIG A;  456C A;  1IAD A;  4XCT A;  2DDF A;  3LJZ A;  966C A;  4J4M A;  1AF0 A;  3LGP A;  4H84 A;  2ERP A;  2O36 A;  5I0L A;  3F18 A;  5LAB A;  2JSD A;  1ZTQ A;  1UTZ A;  1PWU A;  1G05 A;  4Q1L A;  5H8X A;  2OW9 A;  3HBV P;  2OXU A;  3KHI A;  3I7I A;  1A85 A;  2JIH A;  1FBL A;  5D1U A;  1S4B P;  2E3X A;  4JIJ A;  3O64 A;  1BQQ M;  3G5C A;  1B8Y A;  4FU4 A;  3P24 A;  1MNC A;  4XBH A;  1SAT A;  3KEK A;  1ROS A;  3LK8 A;  3WV3 A;  4I35 A;  1QIC A;  5D7W A;  1QIB A;  2POJ A;  4AUO A;  4DF9 A;  3LE9 A;  4DV8 A;  2X3C A;  4L6T A;  1ZXC A;  4GF1 A;  1CK7 A;  1BKC E;  1AST A;  1FLS A;  2A8H A;  1XUD A;  1JIZ A;  4PKS A;  2DDY A;  4GWN A;  1ZS0 A;  1GO7 P;  3EDZ A;  1KUI A;  1PWW A;  1ZXV A;  2TCL A;  2FV9 A;  4G0D A;  4XM7 A;  4JPA A;  1D8F A;  2QPJ A;  4H1Q A;  1UMS A;  1PWP A;  4HMA A;  3LUN A;  2MZH A;  3LJG A;  3DPF A;  1IAA A;  1J7N A;  3WV2 A;  1CGL A;  2WO8 A;  2J83 A;  2OW2 A;  1SRP A;  4FXQ A;  1HFS A;  4AXQ A;  3AYK A;  1C8T A;  1DTH A;  5JMY A;  1K7G A;  5CXA A;  1OM6 A;  2ERO A;  1MMP A;  5CUH A;  3F1A A;  5I3M A;  2DW0 A;  1G4K A;  2JNP A;  3LUM A;  2WOA A;  5B5P A;  3TS4 A;  2OVX A;  1GXD A;  1BUV M;  1L6J A;  2PJT A;  1IAC A;  1JAQ A;  1HTD A;  3KEJ A;  4GUY A;  1G9K A;  3TT4 A;  2DW2 A;  1C3I A;  4I03 A;  1G12 A;  3ZXH A;  5BPA A;  1BQO A;  4PKR A;  1AKL A;  4A3W A;  5CZM A;  1EB6 A;  1JAO A;  1ATL A;  3RTS A;  2OW0 A;  1YOU A;  4IN9 A;  1A86 A;  1OS2 A;  1O0T A;  1EUB A;  2OY4 A;  1JAP A;  3HB2 P;  1RMZ A;  3SHI A;  1I1I P;  1BIW A;  5BOY A;  1GE7 A;  1GO8 P;  1G49 A;  5D2B A;  1MMB A;  2AIG P;  2XS3 A;  3KMC A;  1OS9 A;  2CLT A;  3EDI A;  1Q3A A;  4IUW A;  3KME A;  2DW1 A;  1YQY A;  1XFX A;  1OO9 A;  1Y93 A;  1XFW A;  4PKW A;  1R55 A;  1UEA A;  2W13 A;  3LMC A;  3F19 A;  2N8R A;  2X7M A;  4PKT A;  1UMT A;  1ZVX A;  3V96 B;  1QUA A;  1CAQ A;  2MLS A;  3OHO A;  1EAK A;  3HDB A;  2FV5 A;  1OM7 A;  2MLR A;  2W0D A;  1ND1 A;  1DMT A;  830C A;  5L7F A;  5I2Z A;  5B5O A;  1IAE A;  3L0T A;  1R54 A;  4CTH A;  2K2G A;  5L79 A;  3K7N A;  1YCM A;  3LQB A;  1JIW P;  3HY9 A;  3EDG A;  4GWM A;  1GKC A;  3EHX A;  4JP4 A;  5I4O A;  3ZUK A;  1HFC A;  1CGF A;  4WZV A;  3Q2H A;  3USN A;  3F16 A;  2RJQ A;  1CIZ A;  3HDA P;  1KBC A;  3LKA A;  3TSK A;  1Z3J A;  3UVC A;  3EDH A;  4H49 A;  2Z2D A;  2D1O A;  2YIG A;  4DD8 A;  1QJI A;  1C7K A;  1K7Q A;  4H30 A;  1XFV A;  1KUH A;  1Y8J A;  3DPE A;  1MMR A;  2CKI A;  1JK3 A;  2Y6D A;  1SLN A;  4GR0 A;  1KUF A;  2WO9 A;  4WK7 A;  1H71 P;  1PWQ A;  4WKE A;  2XS4 A;  1HY7 A;  3TVC A;  3E8R A;  3BA0 A;  1Y0V A;  1OMJ A;  3GBO A;  4HX3 A;  3N2U A;  1XFZ A;  2OXW A;  2KRJ A;  3WV1 A;  4G9L A;  4WF6 A;  3RTT A;  1GE5 A;  4PKU A;  1BUD A;  2W15 A;  1D7X A;  1CGE A;  1PWV A;  4L63 A;  1JKY A;  2OVZ A;  1XUC A;  2D1N A;  4H2E A;  3K7L A;  2ERQ A;  2OI0 A;  2OZR A;  4GR8 A;  3VTG A;  3CKI A;  2USN A;  3EHY A;  3F17 A;  4IJO A;  1SLM A;  1XFU A;  1USN A;  2MZE A;  3EWJ A;  2OXZ A;  4DPE A;  1XUR A;  1GE6 A;  3DWB A;  1BZS A;  3OHL A;  1D8M A;  3ZVS A;  4QKZ A;  2AYK A;  4GR3 A;  4WKI A;  2I47 A;  1FM1 A;  3LJT A;  4XM6 A;  4JA1 A;  3DNG A;  3I7G A;  4H3X A;  1JAN A;  1SMP A;  3DSL A;  4H76 A;  1R1J A;  5I12 A;  3Q2G A;  1R1H A;  3ELM A;  3N2V A;  1BM6 A;  3HY7 A;  1HOV A;  2OY2 A;  1O0Q A;  3L0V A;  4ON1 A;  5D1S A;  4AYK A;  1IAG A;  1YP1 A;  3HYG A;  1WNI A;  3DL1 A;  3KEC A;  2Y6C A;  3P1V A;  3B2Z A;  1CXV A;  4A7B A;  2HU6 A;  1BKC A;  4FVL A;  3AYU A;  2K9C A;  2X3B A;  5D3C A;  3KWV C;  5BOT A;  2W14 A;  4ZR5 A;  3B8Z A;  4XM8 A;  2W12 A;  4PKV A;  1KUG A;  3LIL A;  1K7I A;  1IAB A;  3MA2 A;  2L0R A;  1UTT A;  2O3E A;  3LEA A;  1KUK A;  1BSW A;  2JT6 A;  3NX7 A;  5D1T A;  3LIK A;  1D5J A;  3HBU P;  1RM8 A;  1CQR A;  3G42 A;  1JJ9 A;  1I73 A;  1GKD A;  3O2X A;  5I43 A;  2SRT A;  3VI1 A;  1OM8 A;  4FXY P;  4H82 A;  3LIR A;  1XFY A;  2X3A A;  4JQG A;  3KRY A;  2OW1 A;  1B3D A;  1I76 A;  3B92 A;  1QJJ A;  1MMQ A;  3AIG A;  1QIA A;  1JH1 A;  4ILW D;  2RJP A;  4GQL A;  4EFS A;  4R3V A;  1ZP5 A;  1HV5 A;  2E2D A;  2MZI A;  2J0T A;  1BKC I;  2YB9 A;  4L19 A;  1R1I A;  3F15 A; 
#chains in the Genus database with same CATH topology
 1SU3 A;  3U1R A;  3LQ0 A;  1XAX A;  3DTK A;  2JT5 A;  1AYK A;  2V4B A;  4PKQ A;  1KAP P;  4AIG A;  456C A;  1IAD A;  4XCT A;  2DDF A;  3LJZ A;  966C A;  4J4M A;  1AF0 A;  3LGP A;  4H84 A;  2ERP A;  2O36 A;  5I0L A;  3F18 A;  5LAB A;  2JSD A;  1ZTQ A;  1UTZ A;  1PWU A;  1G05 A;  4Q1L A;  5H8X A;  2OW9 A;  3HBV P;  2OXU A;  3KHI A;  3I7I A;  1A85 A;  2JIH A;  1FBL A;  5D1U A;  1S4B P;  2E3X A;  4JIJ A;  3O64 A;  1BQQ M;  3G5C A;  1B8Y A;  4FU4 A;  3P24 A;  1MNC A;  4XBH A;  1SAT A;  3KEK A;  1ROS A;  3LK8 A;  3WV3 A;  4I35 A;  1QIC A;  5D7W A;  3DTE A;  4L7A A;  1QIB A;  2POJ A;  4AUO A;  4DF9 A;  3LE9 A;  4DV8 A;  2X3C A;  4L6T A;  1ZXC A;  2YUF A;  4GF1 A;  1CK7 A;  1BKC E;  1AST A;  1FLS A;  2A8H A;  1XUD A;  1JIZ A;  4PKS A;  2DDY A;  4GWN A;  1ZS0 A;  1GO7 P;  3EDZ A;  1KUI A;  1PWW A;  1ZXV A;  2TCL A;  2FV9 A;  4G0D A;  4XM7 A;  4JPA A;  1D8F A;  2QPJ A;  4H1Q A;  1UMS A;  1PWP A;  4HMA A;  3LUN A;  2MZH A;  3LJG A;  3DPF A;  1IAA A;  1J7N A;  3WV2 A;  1TVI A;  1CGL A;  2WO8 A;  2J83 A;  2OW2 A;  1SRP A;  4FXQ A;  1HFS A;  4AXQ A;  3AYK A;  1C8T A;  1DTH A;  5JMY A;  1K7G A;  5CXA A;  1OM6 A;  2ERO A;  1MMP A;  5CUH A;  3F1A A;  5I3M A;  2DW0 A;  1G4K A;  2JNP A;  3LUM A;  2WOA A;  5B5P A;  3TS4 A;  2OVX A;  1GXD A;  1BUV M;  1L6J A;  2PJT A;  1IAC A;  1JAQ A;  1HTD A;  3KEJ A;  4GUY A;  1G9K A;  3TT4 A;  2DW2 A;  1C3I A;  4I03 A;  1G12 A;  3ZXH A;  5BPA A;  1BQO A;  4PKR A;  1AKL A;  4A3W A;  5CZM A;  1EB6 A;  1JAO A;  1ATL A;  3RTS A;  2OW0 A;  1YOU A;  4IN9 A;  1A86 A;  1OS2 A;  1O0T A;  1EUB A;  2OY4 A;  1JAP A;  3HB2 P;  1RMZ A;  3SHI A;  1I1I P;  1BIW A;  5BOY A;  1GE7 A;  1GO8 P;  1G49 A;  5D2B A;  1MMB A;  2AIG P;  2XS3 A;  3KMC A;  1OS9 A;  2CLT A;  3EDI A;  1Q3A A;  4IUW A;  3KME A;  2DW1 A;  1YQY A;  1XFX A;  1OO9 A;  1Y93 A;  1XFW A;  4PKW A;  1R55 A;  1UEA A;  2W13 A;  3LMC A;  3F19 A;  2N8R A;  2X7M A;  4PKT A;  1UMT A;  1ZVX A;  3V96 B;  1QUA A;  1CAQ A;  2MLS A;  3OHO A;  1EAK A;  3HDB A;  2FV5 A;  1OM7 A;  2MLR A;  2W0D A;  1ND1 A;  1DMT A;  830C A;  5L7F A;  5I2Z A;  5B5O A;  1IAE A;  3L0T A;  1R54 A;  4CTH A;  2K2G A;  5L79 A;  3K7N A;  1YCM A;  3LQB A;  1JIW P;  3HY9 A;  3EDG A;  4GWM A;  1GKC A;  3EHX A;  4JP4 A;  5I4O A;  3ZUK A;  1HFC A;  1CGF A;  4WZV A;  3Q2H A;  3USN A;  3F16 A;  2RJQ A;  1CIZ A;  3HDA P;  1KBC A;  3LKA A;  3TSK A;  1Z3J A;  3UVC A;  3EDH A;  4H49 A;  2Z2D A;  2D1O A;  2YIG A;  4DD8 A;  1QJI A;  1C7K A;  1K7Q A;  4H30 A;  1XFV A;  1KUH A;  1Y8J A;  3DPE A;  1MMR A;  2CKI A;  1JK3 A;  2Y6D A;  1SLN A;  4GR0 A;  1KUF A;  2WO9 A;  4WK7 A;  1H71 P;  1PWQ A;  4WKE A;  2XS4 A;  1HY7 A;  3TVC A;  3E8R A;  3BA0 A;  1Y0V A;  1OMJ A;  3GBO A;  4HX3 A;  3N2U A;  1XFZ A;  2OXW A;  2KRJ A;  3WV1 A;  4G9L A;  4WF6 A;  3RTT A;  1GE5 A;  4PKU A;  1BUD A;  2W15 A;  1D7X A;  1OZ9 A;  1CGE A;  1PWV A;  3DTI A;  4L63 A;  1JKY A;  2OVZ A;  1XUC A;  2D1N A;  4H2E A;  3K7L A;  2ERQ A;  2OI0 A;  2OZR A;  4GR8 A;  3VTG A;  3CKI A;  2USN A;  3EHY A;  3F17 A;  4IJO A;  1SLM A;  1XFU A;  1USN A;  2MZE A;  3EWJ A;  2OXZ A;  4DPE A;  1XUR A;  1GE6 A;  3DWB A;  1BZS A;  3OHL A;  1D8M A;  3ZVS A;  4QKZ A;  2AYK A;  4GR3 A;  4WKI A;  2I47 A;  1FM1 A;  3LJT A;  4XM6 A;  4JA1 A;  3DNG A;  3I7G A;  4H3X A;  1JAN A;  1SMP A;  3DSL A;  4H76 A;  1R1J A;  5I12 A;  3Q2G A;  1R1H A;  3ELM A;  3N2V A;  1BM6 A;  3HY7 A;  1HOV A;  2OY2 A;  1O0Q A;  3L0V A;  4ON1 A;  5D1S A;  4AYK A;  1IAG A;  1YP1 A;  3HYG A;  1WNI A;  3DL1 A;  3KEC A;  2Y6C A;  3P1V A;  3B2Z A;  1CXV A;  4A7B A;  2HU6 A;  1BKC A;  4FVL A;  3AYU A;  2K9C A;  2X3B A;  5D3C A;  3KWV C;  5BOT A;  2W14 A;  4ZR5 A;  3B8Z A;  4XM8 A;  2W12 A;  4PKV A;  1KUG A;  3LIL A;  1K7I A;  1IAB A;  3MA2 A;  2L0R A;  1UTT A;  2O3E A;  3LEA A;  1KUK A;  1BSW A;  2JT6 A;  3NX7 A;  5D1T A;  3LIK A;  1D5J A;  3HBU P;  1RM8 A;  1CQR A;  3G42 A;  1JJ9 A;  1I73 A;  1GKD A;  3O2X A;  5I43 A;  2SRT A;  3VI1 A;  1OM8 A;  4FXY P;  4H82 A;  3LIR A;  1XFY A;  2X3A A;  4JQG A;  3KRY A;  2OW1 A;  1B3D A;  1I76 A;  3B92 A;  1QJJ A;  1MMQ A;  3AIG A;  1QIA A;  1JH1 A;  4ILW D;  2RJP A;  1XM5 A;  4GQL A;  4EFS A;  4R3V A;  1ZP5 A;  1HV5 A;  2E2D A;  2MZI A;  2J0T A;  1BKC I;  2YB9 A;  4L19 A;  1R1I A;  3F15 A; 
#chains in the Genus database with same CATH homology
 1SU3 A;  3U1R A;  3LQ0 A;  3DTK A;  2JT5 A;  1AYK A;  2V4B A;  4PKQ A;  1KAP P;  4AIG A;  456C A;  1IAD A;  4XCT A;  2DDF A;  3LJZ A;  966C A;  4J4M A;  1AF0 A;  3LGP A;  4H84 A;  2ERP A;  2O36 A;  5I0L A;  3F18 A;  5LAB A;  2JSD A;  1ZTQ A;  1UTZ A;  1PWU A;  1G05 A;  4Q1L A;  5H8X A;  2OW9 A;  3HBV P;  2OXU A;  3KHI A;  3I7I A;  1A85 A;  2JIH A;  1FBL A;  5D1U A;  1S4B P;  2E3X A;  4JIJ A;  3O64 A;  1BQQ M;  3G5C A;  1B8Y A;  4FU4 A;  3P24 A;  1MNC A;  4XBH A;  1SAT A;  3KEK A;  1ROS A;  3LK8 A;  3WV3 A;  4I35 A;  1QIC A;  5D7W A;  3DTE A;  4L7A A;  1QIB A;  2POJ A;  4AUO A;  4DF9 A;  3LE9 A;  4DV8 A;  2X3C A;  4L6T A;  1ZXC A;  2YUF A;  4GF1 A;  1CK7 A;  1BKC E;  1AST A;  1FLS A;  2A8H A;  1XUD A;  1JIZ A;  4PKS A;  2DDY A;  4GWN A;  1ZS0 A;  1GO7 P;  3EDZ A;  1KUI A;  1PWW A;  1ZXV A;  2TCL A;  2FV9 A;  4G0D A;  4XM7 A;  4JPA A;  1D8F A;  2QPJ A;  4H1Q A;  1UMS A;  1PWP A;  4HMA A;  3LUN A;  2MZH A;  3LJG A;  3DPF A;  1IAA A;  1J7N A;  3WV2 A;  1CGL A;  2WO8 A;  2J83 A;  2OW2 A;  1SRP A;  4FXQ A;  1HFS A;  4AXQ A;  3AYK A;  1C8T A;  1DTH A;  5JMY A;  1K7G A;  5CXA A;  1OM6 A;  2ERO A;  1MMP A;  5CUH A;  3F1A A;  5I3M A;  2DW0 A;  1G4K A;  2JNP A;  3LUM A;  2WOA A;  5B5P A;  3TS4 A;  2OVX A;  1GXD A;  1BUV M;  1L6J A;  2PJT A;  1IAC A;  1JAQ A;  1HTD A;  3KEJ A;  4GUY A;  1G9K A;  3TT4 A;  2DW2 A;  1C3I A;  4I03 A;  1G12 A;  3ZXH A;  5BPA A;  1BQO A;  4PKR A;  1AKL A;  4A3W A;  5CZM A;  1EB6 A;  1JAO A;  1ATL A;  3RTS A;  2OW0 A;  1YOU A;  4IN9 A;  1A86 A;  1OS2 A;  1O0T A;  1EUB A;  2OY4 A;  1JAP A;  3HB2 P;  1RMZ A;  3SHI A;  1I1I P;  1BIW A;  5BOY A;  1GE7 A;  1GO8 P;  1G49 A;  5D2B A;  1MMB A;  2AIG P;  2XS3 A;  3KMC A;  1OS9 A;  2CLT A;  3EDI A;  1Q3A A;  4IUW A;  3KME A;  2DW1 A;  1YQY A;  1XFX A;  1OO9 A;  1Y93 A;  1XFW A;  4PKW A;  1R55 A;  1UEA A;  2W13 A;  3LMC A;  3F19 A;  2N8R A;  2X7M A;  4PKT A;  1UMT A;  1ZVX A;  3V96 B;  1QUA A;  1CAQ A;  2MLS A;  3OHO A;  1EAK A;  3HDB A;  2FV5 A;  1OM7 A;  2MLR A;  2W0D A;  1ND1 A;  1DMT A;  830C A;  5L7F A;  5I2Z A;  5B5O A;  1IAE A;  3L0T A;  1R54 A;  4CTH A;  2K2G A;  5L79 A;  3K7N A;  1YCM A;  3LQB A;  1JIW P;  3HY9 A;  3EDG A;  4GWM A;  1GKC A;  3EHX A;  4JP4 A;  5I4O A;  3ZUK A;  1HFC A;  1CGF A;  4WZV A;  3Q2H A;  3USN A;  3F16 A;  2RJQ A;  1CIZ A;  3HDA P;  1KBC A;  3LKA A;  3TSK A;  1Z3J A;  3UVC A;  3EDH A;  4H49 A;  2Z2D A;  2D1O A;  2YIG A;  4DD8 A;  1QJI A;  1C7K A;  1K7Q A;  4H30 A;  1XFV A;  1KUH A;  1Y8J A;  3DPE A;  1MMR A;  2CKI A;  1JK3 A;  2Y6D A;  1SLN A;  4GR0 A;  1KUF A;  2WO9 A;  4WK7 A;  1H71 P;  1PWQ A;  4WKE A;  2XS4 A;  1HY7 A;  3TVC A;  3E8R A;  3BA0 A;  1Y0V A;  1OMJ A;  3GBO A;  4HX3 A;  3N2U A;  1XFZ A;  2OXW A;  2KRJ A;  3WV1 A;  4G9L A;  4WF6 A;  3RTT A;  1GE5 A;  4PKU A;  1BUD A;  2W15 A;  1D7X A;  1CGE A;  1PWV A;  3DTI A;  4L63 A;  1JKY A;  2OVZ A;  1XUC A;  2D1N A;  4H2E A;  3K7L A;  2ERQ A;  2OI0 A;  2OZR A;  4GR8 A;  3VTG A;  3CKI A;  2USN A;  3EHY A;  3F17 A;  4IJO A;  1SLM A;  1XFU A;  1USN A;  2MZE A;  3EWJ A;  2OXZ A;  4DPE A;  1XUR A;  1GE6 A;  3DWB A;  1BZS A;  3OHL A;  1D8M A;  3ZVS A;  4QKZ A;  2AYK A;  4GR3 A;  4WKI A;  2I47 A;  1FM1 A;  3LJT A;  4XM6 A;  4JA1 A;  3DNG A;  3I7G A;  4H3X A;  1JAN A;  1SMP A;  3DSL A;  4H76 A;  1R1J A;  5I12 A;  3Q2G A;  1R1H A;  3ELM A;  3N2V A;  1BM6 A;  3HY7 A;  1HOV A;  2OY2 A;  1O0Q A;  3L0V A;  4ON1 A;  5D1S A;  4AYK A;  1IAG A;  1YP1 A;  3HYG A;  1WNI A;  3DL1 A;  3KEC A;  2Y6C A;  3P1V A;  3B2Z A;  1CXV A;  4A7B A;  2HU6 A;  1BKC A;  4FVL A;  3AYU A;  2K9C A;  2X3B A;  5D3C A;  3KWV C;  5BOT A;  2W14 A;  4ZR5 A;  3B8Z A;  4XM8 A;  2W12 A;  4PKV A;  1KUG A;  3LIL A;  1K7I A;  1IAB A;  3MA2 A;  2L0R A;  1UTT A;  2O3E A;  3LEA A;  1KUK A;  1BSW A;  2JT6 A;  3NX7 A;  5D1T A;  3LIK A;  1D5J A;  3HBU P;  1RM8 A;  1CQR A;  3G42 A;  1JJ9 A;  1I73 A;  1GKD A;  3O2X A;  5I43 A;  2SRT A;  3VI1 A;  1OM8 A;  4FXY P;  4H82 A;  3LIR A;  1XFY A;  2X3A A;  4JQG A;  3KRY A;  2OW1 A;  1B3D A;  1I76 A;  3B92 A;  1QJJ A;  1MMQ A;  3AIG A;  1QIA A;  1JH1 A;  4ILW D;  2RJP A;  4GQL A;  4EFS A;  4R3V A;  1ZP5 A;  1HV5 A;  2E2D A;  2MZI A;  2J0T A;  1BKC I;  2YB9 A;  4L19 A;  1R1I A;  3F15 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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