2Y6CA

The discovery of mmp7 inhibitors exploiting a novel selectivity trigger
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
165
structure length
161
Chain Sequence
GYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYPQNFKLSQDDIKGIQKLY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Discovery of Mmp7 Inhibitors Exploiting a Novel Selectivity Trigger.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords MATRILYSIN
total genus 48
structure length 161
sequence length 165
ec nomenclature ec 3.4.24.23: Matrilysin.
pdb deposition date 2011-01-20
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 2y6cA00
3B2ZA 2Z2DA 1ND1A 4A3WA 3UVCA 1OS2A 1H71P 2ERPA 1R1IA 1HY7A 2X3CA 2A8HA 3B8ZA 1XFWA 4HX3A 2OW1A 3HDAP 3DWBA 4JPAA 1XUDA 3B92A 4EFSA 5I3MA 3HY7A 4IJOA 4GF1A 4AIGA 1UMSA 3LJGA 4JQGA 4PKUA 1BUDA 3CKIA 2JNPA 1I73A 3WV1A 1KAPP 1G4KA 1OM6A 1BKCI 3TVCA 1IAEA 3DPEA 4HMAA 1HV5A 3HDBA 2TCLA 4H1QA 2WOAA 1L6JA 1SRPA 2W13A 1CGFA 4ON1A 1CAQA 1ZXCA 1JAQA 1I1IP 1QJJA 1QICA 5CZMA 1BKCE 2K9CA 4PKVA 1EUBA 3ZXHA 1YCMA 3EDIA 1A86A 2L0RA 4GR8A 5L7FA 4GR3A 3EWJA 2CLTA 1RMZA 5I0LA 1JIZA 5CUHA 1S4BP 2PJTA 1CGLA 2X7MA 3V96B 2W0DA 2FV9A 5JMYA 2J0TA 1WNIA 4IN9A 1C3IA 3RTSA 1BSWA 1B3DA 4XCTA 1G12A 2YB9A 4CTHA 3HB2P 2I47A 1CXVA 5H8XA 1YQYA 1PWUA 1UTTA 1AKLA 2OW2A 1O0TA 3G42A 1FLSA 3HYGA 4FU4A 1KUKA 3LJTA 4H84A 5D1UA 5I12A 3LIRA 1JK3A 3HBVP 2JT6A 1QIAA 1Z3JA 2MLRA 2E3XA 3F15A 3EDGA 1FBLA 1GE6A 1ZS0A 2DDYA 3KRYA 1A85A 1DTHA 1UTZA 3Q2HA 1EB6A 3WV3A 5CXAA 1BKCA 1SLNA 1KBCA 2JIHA 1Y0VA 3AYUA 1Y8JA 4PKSA 4ILWD 5LABA 1PWQA 3AYKA 3F16A 4H3XA 4G9LA 1ZP5A 3BA0A 3I7IA 3KEKA 5D2BA 1CGEA 1J7NA 4WKIA 1Y93A 1BQOA 4I35A 1D8MA 3LIKA 3TT4A 3K7NA 2OW9A 4JP4A 1AF0A 1SU3A 1ROSA 2D1NA 1QUAA 3RTTA 1XURA 1I76A 3LE9A 456CA 2CKIA 2DW0A 4GR0A 2AIGP 2O3EA 2MZHA 1HTDA 1D7XA 2DW2A 2OVZA 4FXYP 1UMTA 1IACA 1XFVA 1G49A 1BM6A 2OW0A 3LK8A 3N2VA 1BQQM 5D3CA 3K7LA 1O0QA 5I43A 3HY9A 1BZSA 2D1OA 1KUFA 3LILA 3NX7A 1OM7A 1MNCA 3DPFA 3EDHA 3G5CA 2OY4A 1FM1A 2K2GA 2QPJA 1ZXVA 966CA 3ELMA 4JA1A 4FXQA 5B5PA 3HBUP 4PKTA 3LJZA 1ASTA 1YP1A 3L0TA 1B8YA 1IADA 1GXDA 2JT5A 1XFZA 1MMPA 2MLSA 4GWNA 3P24A 2J83A 3L0VA 1CQRA 4H76A 4H82A 1R1JA 4FVLA 2XS3A 3TS4A 4L6TA 1QIBA 4J4MA 1BUVM 1ZTQA 3VI1A 3WV2A 2POJA 2WO9A 1SATA 1JIWP 2OXWA 3F19A 4IUWA 2W15A 4H30A 1OS9A 1K7IA 1HFCA 4A7BA 3OHOA 2E2DA 1RM8A 1YOUA 2OXUA 4L19A 2ERQA 2JSDA 2USNA 4GWMA 1HFSA 3ZUKA 4Q1LA 1XFYA 2EROA 2RJPA 5L79A 3E8RA 4I03A 3VTGA 2OI0A 4PKWA 1GE7A 3LUMA 2RJQA 2XS4A 2OY2A 4WKEA 5I2ZA 1HOVA 1JH1A 1XFXA 4JIJA 4DPEA 5D1TA 1D5JA 1C7KA 1G9KA 3DSLA 1SMPA 3LQBA 2MZIA 4XM8A 3LEAA 3Q2GA 1GKCA 1GO7P 2WO8A 3EHXA 2Y6CA 3USNA 5D7WA 2N8RA 4H2EA 1KUHA 4DD8A 1IABA 4DF9A 1IAAA 3AIGA 1QJIA 1CIZA 4WF6A 1JANA 1AYKA 3KHIA 3P1VA 3KMCA 2DDFA 1GKDA 4R3VA 2HU6A 1PWWA 2YIGA 2O36A 1JAOA 3MA2A 2KRJA 2OZRA 5D1SA 1C8TA 3ZVSA 3LUNA 4XM6A 3F17A 4DV8A 3U1RA 1EAKA 1MMRA 3EHYA 1ZVXA 2W14A 5BOTA 4H49A 2X3AA 3DL1A 4WK7A 830CA 5I4OA 1R1HA 1JKYA 1Q3AA 1OO9A 2X3BA 1MMBA 5BOYA 5BPAA 1CK7A 1DMTA 2AYKA 1SLMA 4XM7A 1JAPA 1KUGA 4WZVA 1G05A 4AYKA 4G0DA 3F1AA 1UEAA 3OHLA 1JJ9A 1ATLA 3KWVC 3KMEA 1D8FA 1XUCA 3O2XA 4QKZA 4ZR5A 3LQ0A 4AUOA 1XFUA 2FV5A 1R54A 2Y6DA 1GE5A 5B5OA 3SHIA 4GQLA 3GBOA 1OM8A 3O64A 1GO8P 3TSKA 3KECA 3LKAA 1USNA 3I7GA 2OXZA 4PKQA 1R55A 2SRTA 4L63A 3LMCA 1PWVA 1PWPA 1MMQA 3F18A 2W12A 2MZEA 3LGPA 1K7QA 1K7GA 2V4BA 3DNGA 4PKRA 3KEJA 1OMJA 3N2UA 2OVXA 1BIWA 4GUYA 2DW1A 4XBHA 1KUIA 4AXQA 1IAGA 3EDZA
chains in the Genus database with same CATH superfamily
3B2ZA 2Z2DA 1ND1A 4A3WA 3UVCA 1OS2A 1H71P 2ERPA 1R1IA 1HY7A 2X3CA 2A8HA 3B8ZA 1XFWA 4HX3A 2OW1A 3HDAP 3DWBA 4JPAA 1XUDA 3B92A 4EFSA 5I3MA 3HY7A 4IJOA 4GF1A 4AIGA 1UMSA 3LJGA 4JQGA 4PKUA 1BUDA 3CKIA 2JNPA 1I73A 3WV1A 1KAPP 1G4KA 1OM6A 1BKCI 3TVCA 1IAEA 3DPEA 4HMAA 1HV5A 3HDBA 2TCLA 4H1QA 2WOAA 1L6JA 1SRPA 2W13A 1CGFA 4ON1A 1CAQA 1ZXCA 1JAQA 1I1IP 1QJJA 1QICA 5CZMA 1BKCE 2K9CA 4PKVA 1EUBA 3ZXHA 1YCMA 3EDIA 1A86A 2L0RA 4GR8A 1OZ9A 5L7FA 4GR3A 3EWJA 2CLTA 1RMZA 5I0LA 1JIZA 5CUHA 1S4BP 2PJTA 1CGLA 2X7MA 3V96B 2W0DA 2FV9A 5JMYA 2J0TA 1WNIA 4IN9A 1C3IA 3RTSA 4L7AA 1BSWA 1B3DA 4XCTA 1G12A 2YB9A 4CTHA 3HB2P 2I47A 3DTIA 1CXVA 5H8XA 1YQYA 1PWUA 1UTTA 1AKLA 2OW2A 1O0TA 3G42A 1FLSA 3HYGA 4FU4A 1KUKA 3LJTA 4H84A 5D1UA 5I12A 3LIRA 1JK3A 3HBVP 2JT6A 1QIAA 1Z3JA 2MLRA 2E3XA 3F15A 3EDGA 1FBLA 1GE6A 1ZS0A 2DDYA 3KRYA 1A85A 1DTHA 1UTZA 3Q2HA 1EB6A 3WV3A 5CXAA 1BKCA 1SLNA 1KBCA 2JIHA 1Y0VA 3AYUA 1Y8JA 4PKSA 4ILWD 5LABA 1PWQA 3AYKA 3F16A 4H3XA 4G9LA 1ZP5A 3BA0A 3I7IA 3KEKA 5D2BA 1CGEA 1J7NA 4WKIA 1Y93A 1BQOA 4I35A 1D8MA 3LIKA 3TT4A 3K7NA 1XM5A 2OW9A 4JP4A 1AF0A 1SU3A 1ROSA 2D1NA 1QUAA 3RTTA 1XURA 1I76A 3LE9A 456CA 2CKIA 2DW0A 4GR0A 2AIGP 2O3EA 2MZHA 1HTDA 1D7XA 2DW2A 2OVZA 4FXYP 1UMTA 1IACA 1XFVA 1G49A 1BM6A 2OW0A 3LK8A 3N2VA 1BQQM 5D3CA 3K7LA 1O0QA 5I43A 3HY9A 1BZSA 2D1OA 1KUFA 3LILA 3NX7A 1OM7A 1MNCA 3DPFA 3EDHA 3G5CA 2OY4A 1FM1A 2K2GA 2QPJA 1ZXVA 966CA 3ELMA 4JA1A 4FXQA 5B5PA 3HBUP 4PKTA 3LJZA 1ASTA 1YP1A 3L0TA 1B8YA 1IADA 1GXDA 2JT5A 1XFZA 1MMPA 2MLSA 4GWNA 3P24A 2J83A 3L0VA 1CQRA 4H76A 4H82A 1R1JA 4FVLA 2XS3A 3TS4A 4L6TA 1QIBA 4J4MA 1BUVM 1ZTQA 3VI1A 3WV2A 2POJA 2WO9A 1SATA 1JIWP 2OXWA 3F19A 4IUWA 2W15A 4H30A 1OS9A 1K7IA 1HFCA 4A7BA 3OHOA 2E2DA 1RM8A 1YOUA 2OXUA 4L19A 2ERQA 2JSDA 2USNA 4GWMA 1HFSA 3ZUKA 4Q1LA 1XFYA 2EROA 2RJPA 5L79A 3E8RA 4I03A 3VTGA 2OI0A 4PKWA 1GE7A 3LUMA 2RJQA 2XS4A 2OY2A 4WKEA 5I2ZA 1HOVA 1JH1A 1XFXA 4JIJA 4DPEA 5D1TA 1D5JA 1C7KA 1G9KA 3DSLA 1SMPA 3LQBA 2MZIA 4XM8A 3LEAA 3Q2GA 1GKCA 1GO7P 2WO8A 3EHXA 2Y6CA 3USNA 5D7WA 2N8RA 4H2EA 1KUHA 4DD8A 1IABA 4DF9A 1IAAA 3AIGA 1QJIA 1CIZA 4WF6A 1JANA 1AYKA 3KHIA 3P1VA 1TVIA 3KMCA 2DDFA 1GKDA 4R3VA 2HU6A 1PWWA 2YIGA 2O36A 1JAOA 3DTKA 3MA2A 2KRJA 2OZRA 5D1SA 1C8TA 3ZVSA 3LUNA 4XM6A 3F17A 4DV8A 3U1RA 1EAKA 1MMRA 3EHYA 1ZVXA 2W14A 5BOTA 4H49A 1XAXA 2X3AA 3DL1A 4WK7A 830CA 5I4OA 1R1HA 1JKYA 1Q3AA 1OO9A 2X3BA 1MMBA 2YUFA 5BOYA 5BPAA 1CK7A 1DMTA 2AYKA 1SLMA 4XM7A 1JAPA 1KUGA 4WZVA 1G05A 4AYKA 4G0DA 3DTEA 3F1AA 1UEAA 3OHLA 1JJ9A 1ATLA 3KWVC 3KMEA 1D8FA 1XUCA 3O2XA 4QKZA 4ZR5A 3LQ0A 4AUOA 1XFUA 2FV5A 1R54A 2Y6DA 1GE5A 5B5OA 3SHIA 4GQLA 3GBOA 1OM8A 3O64A 1GO8P 3TSKA 3KECA 3LKAA 1USNA 3I7GA 2OXZA 4PKQA 1R55A 2SRTA 4L63A 3LMCA 1PWVA 1PWPA 1MMQA 3F18A 2W12A 2MZEA 3LGPA 1K7QA 1K7GA 2V4BA 3DNGA 4PKRA 3KEJA 1OMJA 3N2UA 2OVXA 1BIWA 4GUYA 2DW1A 4XBHA 1KUIA 4AXQA 1IAGA 3EDZA
chains in the Genus database with same CATH topology
3B2ZA 2Z2DA 1ND1A 4A3WA 3UVCA 1OS2A 1H71P 2ERPA 1R1IA 1HY7A 2X3CA 2A8HA 3B8ZA 1XFWA 4HX3A 2OW1A 3HDAP 3DWBA 4JPAA 1XUDA 3B92A 4EFSA 5I3MA 3HY7A 4IJOA 4GF1A 4AIGA 1UMSA 3LJGA 4JQGA 4PKUA 1BUDA 3CKIA 2JNPA 1I73A 3WV1A 1KAPP 1G4KA 1OM6A 1BKCI 3TVCA 1IAEA 3DPEA 4HMAA 1HV5A 3HDBA 2TCLA 4H1QA 2WOAA 1L6JA 1SRPA 2W13A 1CGFA 4ON1A 1CAQA 1ZXCA 1JAQA 1I1IP 1QJJA 1QICA 5CZMA 1BKCE 2K9CA 4PKVA 1EUBA 3ZXHA 1YCMA 3EDIA 1A86A 2L0RA 4GR8A 5L7FA 4GR3A 3EWJA 2CLTA 1RMZA 5I0LA 1JIZA 5CUHA 1S4BP 2PJTA 1CGLA 2X7MA 3V96B 2W0DA 2FV9A 5JMYA 2J0TA 1WNIA 4IN9A 1C3IA 3RTSA 4L7AA 1BSWA 1B3DA 4XCTA 1G12A 2YB9A 4CTHA 3HB2P 2I47A 3DTIA 1CXVA 5H8XA 1YQYA 1PWUA 1UTTA 1AKLA 2OW2A 1O0TA 3G42A 1FLSA 3HYGA 4FU4A 1KUKA 3LJTA 4H84A 5D1UA 5I12A 3LIRA 1JK3A 3HBVP 2JT6A 1QIAA 1Z3JA 2MLRA 2E3XA 3F15A 3EDGA 1FBLA 1GE6A 1ZS0A 2DDYA 3KRYA 1A85A 1DTHA 1UTZA 3Q2HA 1EB6A 3WV3A 5CXAA 1BKCA 1SLNA 1KBCA 2JIHA 1Y0VA 3AYUA 1Y8JA 4PKSA 4ILWD 5LABA 1PWQA 3AYKA 3F16A 4H3XA 4G9LA 1ZP5A 3BA0A 3I7IA 3KEKA 5D2BA 1CGEA 1J7NA 4WKIA 1Y93A 1BQOA 4I35A 1D8MA 3LIKA 3TT4A 3K7NA 2OW9A 4JP4A 1AF0A 1SU3A 1ROSA 2D1NA 1QUAA 3RTTA 1XURA 1I76A 3LE9A 456CA 2CKIA 2DW0A 4GR0A 2AIGP 2O3EA 2MZHA 1HTDA 1D7XA 2DW2A 2OVZA 4FXYP 1UMTA 1IACA 1XFVA 1G49A 1BM6A 2OW0A 3LK8A 3N2VA 1BQQM 5D3CA 3K7LA 1O0QA 5I43A 3HY9A 1BZSA 2D1OA 1KUFA 3LILA 3NX7A 1OM7A 1MNCA 3DPFA 3EDHA 3G5CA 2OY4A 1FM1A 2K2GA 2QPJA 1ZXVA 966CA 3ELMA 4JA1A 4FXQA 5B5PA 3HBUP 4PKTA 3LJZA 1ASTA 1YP1A 3L0TA 1B8YA 1IADA 1GXDA 2JT5A 1XFZA 1MMPA 2MLSA 4GWNA 3P24A 2J83A 3L0VA 1CQRA 4H76A 4H82A 1R1JA 4FVLA 2XS3A 3TS4A 4L6TA 1QIBA 4J4MA 1BUVM 1ZTQA 3VI1A 3WV2A 2POJA 2WO9A 1SATA 1JIWP 2OXWA 3F19A 4IUWA 2W15A 4H30A 1OS9A 1K7IA 1HFCA 4A7BA 3OHOA 2E2DA 1RM8A 1YOUA 2OXUA 4L19A 2ERQA 2JSDA 2USNA 4GWMA 1HFSA 3ZUKA 4Q1LA 1XFYA 2EROA 2RJPA 5L79A 3E8RA 4I03A 3VTGA 2OI0A 4PKWA 1GE7A 3LUMA 2RJQA 2XS4A 2OY2A 4WKEA 5I2ZA 1HOVA 1JH1A 1XFXA 4JIJA 4DPEA 5D1TA 1D5JA 1C7KA 1G9KA 3DSLA 1SMPA 3LQBA 2MZIA 4XM8A 3LEAA 3Q2GA 1GKCA 1GO7P 2WO8A 3EHXA 2Y6CA 3USNA 5D7WA 2N8RA 4H2EA 1KUHA 4DD8A 1IABA 4DF9A 1IAAA 3AIGA 1QJIA 1CIZA 4WF6A 1JANA 1AYKA 3KHIA 3P1VA 3KMCA 2DDFA 1GKDA 4R3VA 2HU6A 1PWWA 2YIGA 2O36A 1JAOA 3DTKA 3MA2A 2KRJA 2OZRA 5D1SA 1C8TA 3ZVSA 3LUNA 4XM6A 3F17A 4DV8A 3U1RA 1EAKA 1MMRA 3EHYA 1ZVXA 2W14A 5BOTA 4H49A 2X3AA 3DL1A 4WK7A 830CA 5I4OA 1R1HA 1JKYA 1Q3AA 1OO9A 2X3BA 1MMBA 2YUFA 5BOYA 5BPAA 1CK7A 1DMTA 2AYKA 1SLMA 4XM7A 1JAPA 1KUGA 4WZVA 1G05A 4AYKA 4G0DA 3DTEA 3F1AA 1UEAA 3OHLA 1JJ9A 1ATLA 3KWVC 3KMEA 1D8FA 1XUCA 3O2XA 4QKZA 4ZR5A 3LQ0A 4AUOA 1XFUA 2FV5A 1R54A 2Y6DA 1GE5A 5B5OA 3SHIA 4GQLA 3GBOA 1OM8A 3O64A 1GO8P 3TSKA 3KECA 3LKAA 1USNA 3I7GA 2OXZA 4PKQA 1R55A 2SRTA 4L63A 3LMCA 1PWVA 1PWPA 1MMQA 3F18A 2W12A 2MZEA 3LGPA 1K7QA 1K7GA 2V4BA 3DNGA 4PKRA 3KEJA 1OMJA 3N2UA 2OVXA 1BIWA 4GUYA 2DW1A 4XBHA 1KUIA 4AXQA 1IAGA 3EDZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3B2Z A;  2Z2D A;  1ND1 A;  4A3W A;  3UVC A;  1OS2 A;  1H71 P;  2ERP A;  1R1I A;  1HY7 A;  2X3C A;  2A8H A;  3B8Z A;  1XFW A;  4HX3 A;  2OW1 A;  3HDA P;  3DWB A;  4JPA A;  1XUD A;  3B92 A;  4EFS A;  5I3M A;  3HY7 A;  4IJO A;  4GF1 A;  4AIG A;  1UMS A;  3LJG A;  4JQG A;  4PKU A;  1BUD A;  3CKI A;  2JNP A;  1I73 A;  3WV1 A;  1KAP P;  1G4K A;  1OM6 A;  1BKC I;  3TVC A;  1IAE A;  3DPE A;  4HMA A;  1HV5 A;  3HDB A;  2TCL A;  4H1Q A;  2WOA A;  1L6J A;  1SRP A;  2W13 A;  1CGF A;  4ON1 A;  1CAQ A;  1ZXC A;  1JAQ A;  1I1I P;  1QJJ A;  1QIC A;  5CZM A;  1BKC E;  2K9C A;  4PKV A;  1EUB A;  3ZXH A;  1YCM A;  3EDI A;  1A86 A;  2L0R A;  4GR8 A;  5L7F A;  4GR3 A;  3EWJ A;  2CLT A;  1RMZ A;  5I0L A;  1JIZ A;  5CUH A;  1S4B P;  2PJT A;  1CGL A;  2X7M A;  3V96 B;  2W0D A;  2FV9 A;  5JMY A;  2J0T A;  1WNI A;  4IN9 A;  1C3I A;  3RTS A;  1BSW A;  1B3D A;  4XCT A;  1G12 A;  2YB9 A;  4CTH A;  3HB2 P;  2I47 A;  1CXV A;  5H8X A;  1YQY A;  1PWU A;  1UTT A;  1AKL A;  2OW2 A;  1O0T A;  3G42 A;  1FLS A;  3HYG A;  4FU4 A;  1KUK A;  3LJT A;  4H84 A;  5D1U A;  5I12 A;  3LIR A;  1JK3 A;  3HBV P;  2JT6 A;  1QIA A;  1Z3J A;  2MLR A;  2E3X A;  3F15 A;  3EDG A;  1FBL A;  1GE6 A;  1ZS0 A;  2DDY A;  3KRY A;  1A85 A;  1DTH A;  1UTZ A;  3Q2H A;  1EB6 A;  3WV3 A;  5CXA A;  1BKC A;  1SLN A;  1KBC A;  2JIH A;  1Y0V A;  3AYU A;  1Y8J A;  4PKS A;  4ILW D;  5LAB A;  1PWQ A;  3AYK A;  3F16 A;  4H3X A;  4G9L A;  1ZP5 A;  3BA0 A;  3I7I A;  3KEK A;  5D2B A;  1CGE A;  1J7N A;  4WKI A;  1Y93 A;  1BQO A;  4I35 A;  1D8M A;  3LIK A;  3TT4 A;  3K7N A;  2OW9 A;  4JP4 A;  1AF0 A;  1SU3 A;  1ROS A;  2D1N A;  1QUA A;  3RTT A;  1XUR A;  1I76 A;  3LE9 A;  456C A;  2CKI A;  2DW0 A;  4GR0 A;  2AIG P;  2O3E A;  2MZH A;  1HTD A;  1D7X A;  2DW2 A;  2OVZ A;  4FXY P;  1UMT A;  1IAC A;  1XFV A;  1G49 A;  1BM6 A;  2OW0 A;  3LK8 A;  3N2V A;  1BQQ M;  5D3C A;  3K7L A;  1O0Q A;  5I43 A;  3HY9 A;  1BZS A;  2D1O A;  1KUF A;  3LIL A;  3NX7 A;  1OM7 A;  1MNC A;  3DPF A;  3EDH A;  3G5C A;  2OY4 A;  1FM1 A;  2K2G A;  2QPJ A;  1ZXV A;  966C A;  3ELM A;  4JA1 A;  4FXQ A;  5B5P A;  3HBU P;  4PKT A;  3LJZ A;  1AST A;  1YP1 A;  3L0T A;  1B8Y A;  1IAD A;  1GXD A;  2JT5 A;  1XFZ A;  1MMP A;  2MLS A;  4GWN A;  3P24 A;  2J83 A;  3L0V A;  1CQR A;  4H76 A;  4H82 A;  1R1J A;  4FVL A;  2XS3 A;  3TS4 A;  4L6T A;  1QIB A;  4J4M A;  1BUV M;  1ZTQ A;  3VI1 A;  3WV2 A;  2POJ A;  2WO9 A;  1SAT A;  1JIW P;  2OXW A;  3F19 A;  4IUW A;  2W15 A;  4H30 A;  1OS9 A;  1K7I A;  1HFC A;  4A7B A;  3OHO A;  2E2D A;  1RM8 A;  1YOU A;  2OXU A;  4L19 A;  2ERQ A;  2JSD A;  2USN A;  4GWM A;  1HFS A;  3ZUK A;  4Q1L A;  1XFY A;  2ERO A;  2RJP A;  5L79 A;  3E8R A;  4I03 A;  3VTG A;  2OI0 A;  4PKW A;  1GE7 A;  3LUM A;  2RJQ A;  2XS4 A;  2OY2 A;  4WKE A;  5I2Z A;  1HOV A;  1JH1 A;  1XFX A;  4JIJ A;  4DPE A;  5D1T A;  1D5J A;  1C7K A;  1G9K A;  3DSL A;  1SMP A;  3LQB A;  2MZI A;  4XM8 A;  3LEA A;  3Q2G A;  1GKC A;  1GO7 P;  2WO8 A;  3EHX A;  2Y6C A;  3USN A;  5D7W A;  2N8R A;  4H2E A;  1KUH A;  4DD8 A;  1IAB A;  4DF9 A;  1IAA A;  3AIG A;  1QJI A;  1CIZ A;  4WF6 A;  1JAN A;  1AYK A;  3KHI A;  3P1V A;  3KMC A;  2DDF A;  1GKD A;  4R3V A;  2HU6 A;  1PWW A;  2YIG A;  2O36 A;  1JAO A;  3MA2 A;  2KRJ A;  2OZR A;  5D1S A;  1C8T A;  3ZVS A;  3LUN A;  4XM6 A;  3F17 A;  4DV8 A;  3U1R A;  1EAK A;  1MMR A;  3EHY A;  1ZVX A;  2W14 A;  5BOT A;  4H49 A;  2X3A A;  3DL1 A;  4WK7 A;  830C A;  5I4O A;  1R1H A;  1JKY A;  1Q3A A;  1OO9 A;  2X3B A;  1MMB A;  5BOY A;  5BPA A;  1CK7 A;  1DMT A;  2AYK A;  1SLM A;  4XM7 A;  1JAP A;  1KUG A;  4WZV A;  1G05 A;  4AYK A;  4G0D A;  3F1A A;  1UEA A;  3OHL A;  1JJ9 A;  1ATL A;  3KWV C;  3KME A;  1D8F A;  1XUC A;  3O2X A;  4QKZ A;  4ZR5 A;  3LQ0 A;  4AUO A;  1XFU A;  2FV5 A;  1R54 A;  2Y6D A;  1GE5 A;  5B5O A;  3SHI A;  4GQL A;  3GBO A;  1OM8 A;  3O64 A;  1GO8 P;  3TSK A;  3KEC A;  3LKA A;  1USN A;  3I7G A;  2OXZ A;  4PKQ A;  1R55 A;  2SRT A;  4L63 A;  3LMC A;  1PWV A;  1PWP A;  1MMQ A;  3F18 A;  2W12 A;  2MZE A;  3LGP A;  1K7Q A;  1K7G A;  2V4B A;  3DNG A;  4PKR A;  3KEJ A;  1OMJ A;  3N2U A;  2OVX A;  1BIW A;  4GUY A;  2DW1 A;  4XBH A;  1KUI A;  4AXQ A;  1IAG A;  3EDZ A; 
#chains in the Genus database with same CATH topology
 3B2Z A;  2Z2D A;  1ND1 A;  4A3W A;  3UVC A;  1OS2 A;  1H71 P;  2ERP A;  1R1I A;  1HY7 A;  2X3C A;  2A8H A;  3B8Z A;  1XFW A;  4HX3 A;  2OW1 A;  3HDA P;  3DWB A;  4JPA A;  1XUD A;  3B92 A;  4EFS A;  5I3M A;  3HY7 A;  4IJO A;  4GF1 A;  4AIG A;  1UMS A;  3LJG A;  4JQG A;  4PKU A;  1BUD A;  3CKI A;  2JNP A;  1I73 A;  3WV1 A;  1KAP P;  1G4K A;  1OM6 A;  1BKC I;  3TVC A;  1IAE A;  3DPE A;  4HMA A;  1HV5 A;  3HDB A;  2TCL A;  4H1Q A;  2WOA A;  1L6J A;  1SRP A;  2W13 A;  1CGF A;  4ON1 A;  1CAQ A;  1ZXC A;  1JAQ A;  1I1I P;  1QJJ A;  1QIC A;  5CZM A;  1BKC E;  2K9C A;  4PKV A;  1EUB A;  3ZXH A;  1YCM A;  3EDI A;  1A86 A;  2L0R A;  4GR8 A;  1OZ9 A;  5L7F A;  4GR3 A;  3EWJ A;  2CLT A;  1RMZ A;  5I0L A;  1JIZ A;  5CUH A;  1S4B P;  2PJT A;  1CGL A;  2X7M A;  3V96 B;  2W0D A;  2FV9 A;  5JMY A;  2J0T A;  1WNI A;  4IN9 A;  1C3I A;  3RTS A;  4L7A A;  1BSW A;  1B3D A;  4XCT A;  1G12 A;  2YB9 A;  4CTH A;  3HB2 P;  2I47 A;  3DTI A;  1CXV A;  5H8X A;  1YQY A;  1PWU A;  1UTT A;  1AKL A;  2OW2 A;  1O0T A;  3G42 A;  1FLS A;  3HYG A;  4FU4 A;  1KUK A;  3LJT A;  4H84 A;  5D1U A;  5I12 A;  3LIR A;  1JK3 A;  3HBV P;  2JT6 A;  1QIA A;  1Z3J A;  2MLR A;  2E3X A;  3F15 A;  3EDG A;  1FBL A;  1GE6 A;  1ZS0 A;  2DDY A;  3KRY A;  1A85 A;  1DTH A;  1UTZ A;  3Q2H A;  1EB6 A;  3WV3 A;  5CXA A;  1BKC A;  1SLN A;  1KBC A;  2JIH A;  1Y0V A;  3AYU A;  1Y8J A;  4PKS A;  4ILW D;  5LAB A;  1PWQ A;  3AYK A;  3F16 A;  4H3X A;  4G9L A;  1ZP5 A;  3BA0 A;  3I7I A;  3KEK A;  5D2B A;  1CGE A;  1J7N A;  4WKI A;  1Y93 A;  1BQO A;  4I35 A;  1D8M A;  3LIK A;  3TT4 A;  3K7N A;  1XM5 A;  2OW9 A;  4JP4 A;  1AF0 A;  1SU3 A;  1ROS A;  2D1N A;  1QUA A;  3RTT A;  1XUR A;  1I76 A;  3LE9 A;  456C A;  2CKI A;  2DW0 A;  4GR0 A;  2AIG P;  2O3E A;  2MZH A;  1HTD A;  1D7X A;  2DW2 A;  2OVZ A;  4FXY P;  1UMT A;  1IAC A;  1XFV A;  1G49 A;  1BM6 A;  2OW0 A;  3LK8 A;  3N2V A;  1BQQ M;  5D3C A;  3K7L A;  1O0Q A;  5I43 A;  3HY9 A;  1BZS A;  2D1O A;  1KUF A;  3LIL A;  3NX7 A;  1OM7 A;  1MNC A;  3DPF A;  3EDH A;  3G5C A;  2OY4 A;  1FM1 A;  2K2G A;  2QPJ A;  1ZXV A;  966C A;  3ELM A;  4JA1 A;  4FXQ A;  5B5P A;  3HBU P;  4PKT A;  3LJZ A;  1AST A;  1YP1 A;  3L0T A;  1B8Y A;  1IAD A;  1GXD A;  2JT5 A;  1XFZ A;  1MMP A;  2MLS A;  4GWN A;  3P24 A;  2J83 A;  3L0V A;  1CQR A;  4H76 A;  4H82 A;  1R1J A;  4FVL A;  2XS3 A;  3TS4 A;  4L6T A;  1QIB A;  4J4M A;  1BUV M;  1ZTQ A;  3VI1 A;  3WV2 A;  2POJ A;  2WO9 A;  1SAT A;  1JIW P;  2OXW A;  3F19 A;  4IUW A;  2W15 A;  4H30 A;  1OS9 A;  1K7I A;  1HFC A;  4A7B A;  3OHO A;  2E2D A;  1RM8 A;  1YOU A;  2OXU A;  4L19 A;  2ERQ A;  2JSD A;  2USN A;  4GWM A;  1HFS A;  3ZUK A;  4Q1L A;  1XFY A;  2ERO A;  2RJP A;  5L79 A;  3E8R A;  4I03 A;  3VTG A;  2OI0 A;  4PKW A;  1GE7 A;  3LUM A;  2RJQ A;  2XS4 A;  2OY2 A;  4WKE A;  5I2Z A;  1HOV A;  1JH1 A;  1XFX A;  4JIJ A;  4DPE A;  5D1T A;  1D5J A;  1C7K A;  1G9K A;  3DSL A;  1SMP A;  3LQB A;  2MZI A;  4XM8 A;  3LEA A;  3Q2G A;  1GKC A;  1GO7 P;  2WO8 A;  3EHX A;  2Y6C A;  3USN A;  5D7W A;  2N8R A;  4H2E A;  1KUH A;  4DD8 A;  1IAB A;  4DF9 A;  1IAA A;  3AIG A;  1QJI A;  1CIZ A;  4WF6 A;  1JAN A;  1AYK A;  3KHI A;  3P1V A;  1TVI A;  3KMC A;  2DDF A;  1GKD A;  4R3V A;  2HU6 A;  1PWW A;  2YIG A;  2O36 A;  1JAO A;  3DTK A;  3MA2 A;  2KRJ A;  2OZR A;  5D1S A;  1C8T A;  3ZVS A;  3LUN A;  4XM6 A;  3F17 A;  4DV8 A;  3U1R A;  1EAK A;  1MMR A;  3EHY A;  1ZVX A;  2W14 A;  5BOT A;  4H49 A;  1XAX A;  2X3A A;  3DL1 A;  4WK7 A;  830C A;  5I4O A;  1R1H A;  1JKY A;  1Q3A A;  1OO9 A;  2X3B A;  1MMB A;  2YUF A;  5BOY A;  5BPA A;  1CK7 A;  1DMT A;  2AYK A;  1SLM A;  4XM7 A;  1JAP A;  1KUG A;  4WZV A;  1G05 A;  4AYK A;  4G0D A;  3DTE A;  3F1A A;  1UEA A;  3OHL A;  1JJ9 A;  1ATL A;  3KWV C;  3KME A;  1D8F A;  1XUC A;  3O2X A;  4QKZ A;  4ZR5 A;  3LQ0 A;  4AUO A;  1XFU A;  2FV5 A;  1R54 A;  2Y6D A;  1GE5 A;  5B5O A;  3SHI A;  4GQL A;  3GBO A;  1OM8 A;  3O64 A;  1GO8 P;  3TSK A;  3KEC A;  3LKA A;  1USN A;  3I7G A;  2OXZ A;  4PKQ A;  1R55 A;  2SRT A;  4L63 A;  3LMC A;  1PWV A;  1PWP A;  1MMQ A;  3F18 A;  2W12 A;  2MZE A;  3LGP A;  1K7Q A;  1K7G A;  2V4B A;  3DNG A;  4PKR A;  3KEJ A;  1OMJ A;  3N2U A;  2OVX A;  1BIW A;  4GUY A;  2DW1 A;  4XBH A;  1KUI A;  4AXQ A;  1IAG A;  3EDZ A; 
#chains in the Genus database with same CATH homology
 3B2Z A;  2Z2D A;  1ND1 A;  4A3W A;  3UVC A;  1OS2 A;  1H71 P;  2ERP A;  1R1I A;  1HY7 A;  2X3C A;  2A8H A;  3B8Z A;  1XFW A;  4HX3 A;  2OW1 A;  3HDA P;  3DWB A;  4JPA A;  1XUD A;  3B92 A;  4EFS A;  5I3M A;  3HY7 A;  4IJO A;  4GF1 A;  4AIG A;  1UMS A;  3LJG A;  4JQG A;  4PKU A;  1BUD A;  3CKI A;  2JNP A;  1I73 A;  3WV1 A;  1KAP P;  1G4K A;  1OM6 A;  1BKC I;  3TVC A;  1IAE A;  3DPE A;  4HMA A;  1HV5 A;  3HDB A;  2TCL A;  4H1Q A;  2WOA A;  1L6J A;  1SRP A;  2W13 A;  1CGF A;  4ON1 A;  1CAQ A;  1ZXC A;  1JAQ A;  1I1I P;  1QJJ A;  1QIC A;  5CZM A;  1BKC E;  2K9C A;  4PKV A;  1EUB A;  3ZXH A;  1YCM A;  3EDI A;  1A86 A;  2L0R A;  4GR8 A;  5L7F A;  4GR3 A;  3EWJ A;  2CLT A;  1RMZ A;  5I0L A;  1JIZ A;  5CUH A;  1S4B P;  2PJT A;  1CGL A;  2X7M A;  3V96 B;  2W0D A;  2FV9 A;  5JMY A;  2J0T A;  1WNI A;  4IN9 A;  1C3I A;  3RTS A;  4L7A A;  1BSW A;  1B3D A;  4XCT A;  1G12 A;  2YB9 A;  4CTH A;  3HB2 P;  2I47 A;  3DTI A;  1CXV A;  5H8X A;  1YQY A;  1PWU A;  1UTT A;  1AKL A;  2OW2 A;  1O0T A;  3G42 A;  1FLS A;  3HYG A;  4FU4 A;  1KUK A;  3LJT A;  4H84 A;  5D1U A;  5I12 A;  3LIR A;  1JK3 A;  3HBV P;  2JT6 A;  1QIA A;  1Z3J A;  2MLR A;  2E3X A;  3F15 A;  3EDG A;  1FBL A;  1GE6 A;  1ZS0 A;  2DDY A;  3KRY A;  1A85 A;  1DTH A;  1UTZ A;  3Q2H A;  1EB6 A;  3WV3 A;  5CXA A;  1BKC A;  1SLN A;  1KBC A;  2JIH A;  1Y0V A;  3AYU A;  1Y8J A;  4PKS A;  4ILW D;  5LAB A;  1PWQ A;  3AYK A;  3F16 A;  4H3X A;  4G9L A;  1ZP5 A;  3BA0 A;  3I7I A;  3KEK A;  5D2B A;  1CGE A;  1J7N A;  4WKI A;  1Y93 A;  1BQO A;  4I35 A;  1D8M A;  3LIK A;  3TT4 A;  3K7N A;  2OW9 A;  4JP4 A;  1AF0 A;  1SU3 A;  1ROS A;  2D1N A;  1QUA A;  3RTT A;  1XUR A;  1I76 A;  3LE9 A;  456C A;  2CKI A;  2DW0 A;  4GR0 A;  2AIG P;  2O3E A;  2MZH A;  1HTD A;  1D7X A;  2DW2 A;  2OVZ A;  4FXY P;  1UMT A;  1IAC A;  1XFV A;  1G49 A;  1BM6 A;  2OW0 A;  3LK8 A;  3N2V A;  1BQQ M;  5D3C A;  3K7L A;  1O0Q A;  5I43 A;  3HY9 A;  1BZS A;  2D1O A;  1KUF A;  3LIL A;  3NX7 A;  1OM7 A;  1MNC A;  3DPF A;  3EDH A;  3G5C A;  2OY4 A;  1FM1 A;  2K2G A;  2QPJ A;  1ZXV A;  966C A;  3ELM A;  4JA1 A;  4FXQ A;  5B5P A;  3HBU P;  4PKT A;  3LJZ A;  1AST A;  1YP1 A;  3L0T A;  1B8Y A;  1IAD A;  1GXD A;  2JT5 A;  1XFZ A;  1MMP A;  2MLS A;  4GWN A;  3P24 A;  2J83 A;  3L0V A;  1CQR A;  4H76 A;  4H82 A;  1R1J A;  4FVL A;  2XS3 A;  3TS4 A;  4L6T A;  1QIB A;  4J4M A;  1BUV M;  1ZTQ A;  3VI1 A;  3WV2 A;  2POJ A;  2WO9 A;  1SAT A;  1JIW P;  2OXW A;  3F19 A;  4IUW A;  2W15 A;  4H30 A;  1OS9 A;  1K7I A;  1HFC A;  4A7B A;  3OHO A;  2E2D A;  1RM8 A;  1YOU A;  2OXU A;  4L19 A;  2ERQ A;  2JSD A;  2USN A;  4GWM A;  1HFS A;  3ZUK A;  4Q1L A;  1XFY A;  2ERO A;  2RJP A;  5L79 A;  3E8R A;  4I03 A;  3VTG A;  2OI0 A;  4PKW A;  1GE7 A;  3LUM A;  2RJQ A;  2XS4 A;  2OY2 A;  4WKE A;  5I2Z A;  1HOV A;  1JH1 A;  1XFX A;  4JIJ A;  4DPE A;  5D1T A;  1D5J A;  1C7K A;  1G9K A;  3DSL A;  1SMP A;  3LQB A;  2MZI A;  4XM8 A;  3LEA A;  3Q2G A;  1GKC A;  1GO7 P;  2WO8 A;  3EHX A;  2Y6C A;  3USN A;  5D7W A;  2N8R A;  4H2E A;  1KUH A;  4DD8 A;  1IAB A;  4DF9 A;  1IAA A;  3AIG A;  1QJI A;  1CIZ A;  4WF6 A;  1JAN A;  1AYK A;  3KHI A;  3P1V A;  3KMC A;  2DDF A;  1GKD A;  4R3V A;  2HU6 A;  1PWW A;  2YIG A;  2O36 A;  1JAO A;  3DTK A;  3MA2 A;  2KRJ A;  2OZR A;  5D1S A;  1C8T A;  3ZVS A;  3LUN A;  4XM6 A;  3F17 A;  4DV8 A;  3U1R A;  1EAK A;  1MMR A;  3EHY A;  1ZVX A;  2W14 A;  5BOT A;  4H49 A;  2X3A A;  3DL1 A;  4WK7 A;  830C A;  5I4O A;  1R1H A;  1JKY A;  1Q3A A;  1OO9 A;  2X3B A;  1MMB A;  2YUF A;  5BOY A;  5BPA A;  1CK7 A;  1DMT A;  2AYK A;  1SLM A;  4XM7 A;  1JAP A;  1KUG A;  4WZV A;  1G05 A;  4AYK A;  4G0D A;  3DTE A;  3F1A A;  1UEA A;  3OHL A;  1JJ9 A;  1ATL A;  3KWV C;  3KME A;  1D8F A;  1XUC A;  3O2X A;  4QKZ A;  4ZR5 A;  3LQ0 A;  4AUO A;  1XFU A;  2FV5 A;  1R54 A;  2Y6D A;  1GE5 A;  5B5O A;  3SHI A;  4GQL A;  3GBO A;  1OM8 A;  3O64 A;  1GO8 P;  3TSK A;  3KEC A;  3LKA A;  1USN A;  3I7G A;  2OXZ A;  4PKQ A;  1R55 A;  2SRT A;  4L63 A;  3LMC A;  1PWV A;  1PWP A;  1MMQ A;  3F18 A;  2W12 A;  2MZE A;  3LGP A;  1K7Q A;  1K7G A;  2V4B A;  3DNG A;  4PKR A;  3KEJ A;  1OMJ A;  3N2U A;  2OVX A;  1BIW A;  4GUY A;  2DW1 A;  4XBH A;  1KUI A;  4AXQ A;  1IAG A;  3EDZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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