2Y6DA

The discovery of mmp7 inhibitors exploiting a novel selectivity trigger
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
166
structure length
159
Chain Sequence
GYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYFKLSQDDIKGIQKLYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Discovery of Mmp7 Inhibitors Exploiting a Novel Selectivity Trigger.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords MATRILYSIN
total genus 48
structure length 159
sequence length 166
ec nomenclature ec 3.4.24.23: Matrilysin.
pdb deposition date 2011-01-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 2y6dA00
1ZXCA 3E8RA 1AYKA 1BIWA 1Z3JA 2SRTA 4WK7A 3V96B 1ZS0A 1ROSA 3KHIA 3MA2A 2OXWA 1CAQA 1YCMA 2XS4A 1IACA 3OHLA 2MLSA 2W0DA 3EHXA 4H49A 1KUFA 1XFXA 1WNIA 2MZEA 2QPJA 3ELMA 1SATA 2ERQA 1GXDA 1I1IP 1OS2A 4ON1A 4XM8A 4PKVA 1EAKA 3I7IA 2HU6A 3B8ZA 1RMZA 1IADA 1ZVXA 4L6TA 4XCTA 3AIGA 4IJOA 5I0LA 4DPEA 1C8TA 1JK3A 3L0TA 2DW1A 1JAOA 3EDIA 1CQRA 3SHIA 5D1UA 2WOAA 3LJTA 3WV1A 2OY4A 3ZVSA 1HOVA 3TT4A 1C3IA 3BA0A 1MMQA 2OW9A 2E2DA 1R1IA 3B2ZA 3DWBA 3RTTA 4FXYP 1QJIA 3RTSA 4FVLA 1MMPA 4DV8A 2OXUA 3Q2HA 4H2EA 1O0QA 1G12A 1UTTA 2OW0A 3DPEA 4GR3A 3Q2GA 1XUCA 4GUYA 3HDAP 2W14A 1B8YA 1KUGA 2JT6A 1I76A 4GQLA 3G5CA 1CIZA 2WO8A 2OW2A 1K7QA 3F18A 1AF0A 4A3WA 3CKIA 1S4BP 4ILWD 4A7BA 3EWJA 1R55A 3TVCA 1BUDA 1FLSA 3HB2P 1KUIA 1JAPA 3WV3A 1J7NA 3LILA 1IAEA 2L0RA 3KECA 2AYKA 1OM7A 2V4BA 2W13A 3DL1A 5CZMA 1I73A 5CUHA 3ZXHA 1HTDA 1G49A 3DNGA 3F17A 1OM6A 4GF1A 1FBLA 1BUVM 4DF9A 4JP4A 1YQYA 3KMCA 3VTGA 1BM6A 1SRPA 5I3MA 1QIAA 1R1JA 2YB9A 3EHYA 1D8MA 2A8HA 4HX3A 4AYKA 1XFUA 2Y6DA 2AIGP 3L0VA 3VI1A 3K7NA 5D3CA 4G9LA 3N2VA 4WKEA 2JIHA 1A85A 5D1SA 3KEKA 1Y8JA 3UVCA 4HMAA 4I35A 1PWWA 1KAPP 3HDBA 1KUKA 3LE9A 2POJA 1GKDA 1MNCA 1R54A 3LIKA 2EROA 4R3VA 1XURA 5BPAA 1PWPA 3P1VA 3O64A 4AUOA 3EDZA 1XFWA 2WO9A 2FV5A 830CA 4IUWA 3LUMA 1SLMA 456CA 2E3XA 2DDFA 1D8FA 2OI0A 3I7GA 4FU4A 1IAGA 1G9KA 3DPFA 4GWNA 2RJQA 2FV9A 2MLRA 2X7MA 4H76A 2D1OA 1HFCA 1L6JA 5B5OA 1XFZA 1IABA 1PWUA 1Y93A 4FXQA 2OVZA 4PKQA 1BZSA 2OY2A 3LUNA 5H8XA 3HY7A 4JIJA 1HV5A 2Z2DA 4H3XA 1GO7P 4PKRA 3LGPA 3KWVC 3F19A 2CLTA 3LKAA 1FM1A 3GBOA 1G4KA 2OXZA 2DW2A 1CXVA 1ATLA 1ND1A 1G05A 3G42A 1RM8A 2X3AA 2JT5A 4H84A 1YP1A 2OVXA 1D5JA 4PKTA 4DD8A 1OO9A 1DMTA 1XUDA 4J4MA 1USNA 1HY7A 1CK7A 1SU3A 1UTZA 1Q3AA 1SMPA 2X3BA 1BKCE 1OM8A 1BQOA 3HBVP 5D2BA 3HBUP 1Y0VA 1K7IA 3HY9A 4WZVA 5I2ZA 1CGFA 1JAQA 3LQBA 4WKIA 1CGEA 4XM6A 1O0TA 3AYKA 1QJJA 3KEJA 2TCLA 1ZTQA 1JIWP 3O2XA 5BOTA 1BKCA 1PWVA 1JANA 3B92A 5BOYA 4L63A 3AYUA 1KBCA 2KRJA 3KRYA 2XS3A 1ASTA 4XBHA 1A86A 1UMTA 2X3CA 1XFYA 4G0DA 1KUHA 1GKCA 2MZHA 2YIGA 3LIRA 5I43A 4EFSA 4H82A 3EDGA 2O36A 2OZRA 2W15A 3NX7A 1D7XA 2N8RA 1K7GA 5D7WA 3LMCA 1OMJA 1SLNA 1GE5A 5CXAA 4GR8A 1GE6A 1BSWA 966CA 2CKIA 2RJPA 4H1QA 1B3DA 1QUAA 4I03A 3OHOA 1OS9A 1AKLA 4ZR5A 1IAAA 1C7KA 2O3EA 5L7FA 2JNPA 2Y6CA 5I4OA 2OW1A 4PKSA 4CTHA 4XM7A 2J83A 3F1AA 1EUBA 4L19A 1BQQM 3LJZA 4GR0A 3LQ0A 1HFSA 1MMRA 3HYGA 3WV2A 4IN9A 1YOUA 1JKYA 1CGLA 2USNA 1JIZA 4AXQA 4H30A 1EB6A 1UEAA 2K2GA 1QIBA 2JSDA 1XFVA 3EDHA 1QICA 1JJ9A 2ERPA 3DSLA 3F16A 5D1TA 4AIGA 3K7LA 1GE7A 5JMYA 2D1NA 5LABA 4QKZA 1BKCI 3N2UA 2J0TA 5L79A 1R1HA 3LJGA 4PKUA 2K9CA 3P24A 3USNA 2DDYA 3TS4A 1ZXVA 1DTHA 3ZUKA 1PWQA 4GWMA 2W12A 2MZIA 2DW0A 2PJTA 4JQGA 3TSKA 4JA1A 1JH1A 2I47A 1GO8P 4WF6A 4Q1LA 4PKWA 3U1RA 1MMBA 3KMEA 3LEAA 1ZP5A 4JPAA 5I12A 5B5PA 1H71P 3LK8A 1UMSA 3F15A
chains in the Genus database with same CATH superfamily
1ZXCA 3E8RA 1AYKA 1BIWA 1Z3JA 2SRTA 4WK7A 3V96B 1ZS0A 1ROSA 3KHIA 3MA2A 2OXWA 1CAQA 1YCMA 2XS4A 1IACA 3OHLA 2MLSA 2W0DA 3EHXA 4H49A 1KUFA 1XFXA 1WNIA 2MZEA 2QPJA 3ELMA 1SATA 2ERQA 1GXDA 1I1IP 1OS2A 4ON1A 4XM8A 4PKVA 1EAKA 3I7IA 2HU6A 3B8ZA 1RMZA 1IADA 1ZVXA 4L6TA 4XCTA 3DTKA 2YUFA 3AIGA 4IJOA 5I0LA 4DPEA 1C8TA 1JK3A 3L0TA 2DW1A 1JAOA 3EDIA 4L7AA 1CQRA 3SHIA 5D1UA 2WOAA 3LJTA 3WV1A 2OY4A 3ZVSA 1HOVA 3TT4A 1C3IA 3BA0A 1MMQA 2OW9A 2E2DA 1R1IA 3B2ZA 3DWBA 3RTTA 4FXYP 1QJIA 3RTSA 4FVLA 1MMPA 4DV8A 2OXUA 3Q2HA 4H2EA 1O0QA 1G12A 1UTTA 2OW0A 3DPEA 4GR3A 3Q2GA 1XUCA 4GUYA 3HDAP 2W14A 1B8YA 1KUGA 2JT6A 1I76A 4GQLA 3G5CA 1CIZA 2WO8A 2OW2A 1K7QA 3F18A 1AF0A 4A3WA 3CKIA 1S4BP 4ILWD 4A7BA 3EWJA 1R55A 3TVCA 1BUDA 1FLSA 3HB2P 1KUIA 1JAPA 1TVIA 3WV3A 1J7NA 3LILA 1IAEA 2L0RA 3KECA 2AYKA 1OM7A 2V4BA 2W13A 3DL1A 5CZMA 1I73A 5CUHA 3ZXHA 1HTDA 1G49A 3DNGA 3F17A 1OM6A 4GF1A 1FBLA 1BUVM 4DF9A 4JP4A 1YQYA 3KMCA 3VTGA 1BM6A 1SRPA 5I3MA 1QIAA 1R1JA 2YB9A 3EHYA 1D8MA 2A8HA 4HX3A 4AYKA 1XFUA 2Y6DA 2AIGP 3L0VA 3VI1A 3K7NA 5D3CA 1XAXA 4G9LA 3N2VA 4WKEA 2JIHA 1A85A 5D1SA 3KEKA 1Y8JA 3UVCA 4HMAA 4I35A 1PWWA 1KAPP 3HDBA 1KUKA 3LE9A 2POJA 1GKDA 1MNCA 1R54A 3LIKA 2EROA 4R3VA 1XURA 5BPAA 1PWPA 3P1VA 3O64A 4AUOA 3EDZA 1XFWA 2WO9A 2FV5A 830CA 4IUWA 3LUMA 1SLMA 456CA 2E3XA 2DDFA 1D8FA 2OI0A 3I7GA 4FU4A 1IAGA 1G9KA 3DPFA 4GWNA 2RJQA 2FV9A 2MLRA 2X7MA 4H76A 2D1OA 1HFCA 1L6JA 5B5OA 1XFZA 1IABA 1PWUA 1Y93A 4FXQA 2OVZA 4PKQA 1BZSA 2OY2A 3LUNA 5H8XA 3HY7A 4JIJA 1HV5A 2Z2DA 4H3XA 1GO7P 4PKRA 3LGPA 3KWVC 3F19A 2CLTA 3LKAA 1FM1A 3GBOA 1G4KA 2OXZA 2DW2A 1CXVA 1ATLA 1ND1A 1G05A 3G42A 1RM8A 2X3AA 2JT5A 4H84A 1YP1A 2OVXA 1D5JA 4PKTA 4DD8A 1OO9A 1DMTA 1XUDA 4J4MA 1USNA 1HY7A 1CK7A 1SU3A 1UTZA 1Q3AA 1SMPA 2X3BA 1BKCE 1OM8A 1BQOA 3HBVP 1XM5A 5D2BA 3HBUP 1Y0VA 1K7IA 3HY9A 4WZVA 5I2ZA 1CGFA 1JAQA 3LQBA 4WKIA 1CGEA 4XM6A 1O0TA 3AYKA 1QJJA 3KEJA 2TCLA 1ZTQA 1JIWP 3O2XA 5BOTA 1BKCA 1PWVA 1JANA 3B92A 5BOYA 4L63A 3AYUA 1KBCA 2KRJA 3KRYA 2XS3A 1ASTA 4XBHA 1A86A 1UMTA 2X3CA 1XFYA 4G0DA 1KUHA 1GKCA 2MZHA 2YIGA 3LIRA 5I43A 4EFSA 4H82A 3EDGA 2O36A 2OZRA 2W15A 3NX7A 1D7XA 2N8RA 1K7GA 5D7WA 3LMCA 1OMJA 1SLNA 1GE5A 5CXAA 4GR8A 1GE6A 1BSWA 966CA 2CKIA 2RJPA 4H1QA 3DTIA 1B3DA 1QUAA 4I03A 3OHOA 1OS9A 1AKLA 4ZR5A 1IAAA 1C7KA 2O3EA 5L7FA 2JNPA 2Y6CA 5I4OA 2OW1A 4PKSA 4CTHA 4XM7A 2J83A 3F1AA 1EUBA 4L19A 1BQQM 3LJZA 4GR0A 3LQ0A 1HFSA 1MMRA 3HYGA 3WV2A 4IN9A 1YOUA 1JKYA 1CGLA 2USNA 1JIZA 4AXQA 4H30A 1EB6A 1UEAA 2K2GA 1QIBA 2JSDA 1XFVA 3EDHA 1QICA 1JJ9A 2ERPA 3DSLA 3F16A 5D1TA 4AIGA 3K7LA 1GE7A 5JMYA 2D1NA 5LABA 4QKZA 1BKCI 3N2UA 2J0TA 5L79A 1R1HA 3LJGA 4PKUA 2K9CA 3P24A 3USNA 2DDYA 3TS4A 1ZXVA 1DTHA 3DTEA 3ZUKA 1PWQA 4GWMA 2W12A 2MZIA 2DW0A 2PJTA 4JQGA 3TSKA 4JA1A 1JH1A 2I47A 1GO8P 4WF6A 4Q1LA 4PKWA 3U1RA 1MMBA 3KMEA 3LEAA 1ZP5A 4JPAA 5I12A 5B5PA 1H71P 3LK8A 1UMSA 3F15A 1OZ9A
chains in the Genus database with same CATH topology
1ZXCA 3E8RA 1AYKA 1BIWA 1Z3JA 2SRTA 4WK7A 3V96B 1ZS0A 1ROSA 3KHIA 3MA2A 2OXWA 1CAQA 1YCMA 2XS4A 1IACA 3OHLA 2MLSA 2W0DA 3EHXA 4H49A 1KUFA 1XFXA 1WNIA 2MZEA 2QPJA 3ELMA 1SATA 2ERQA 1GXDA 1I1IP 1OS2A 4ON1A 4XM8A 4PKVA 1EAKA 3I7IA 2HU6A 3B8ZA 1RMZA 1IADA 1ZVXA 4L6TA 4XCTA 3DTKA 2YUFA 3AIGA 4IJOA 5I0LA 4DPEA 1C8TA 1JK3A 3L0TA 2DW1A 1JAOA 3EDIA 4L7AA 1CQRA 3SHIA 5D1UA 2WOAA 3LJTA 3WV1A 2OY4A 3ZVSA 1HOVA 3TT4A 1C3IA 3BA0A 1MMQA 2OW9A 2E2DA 1R1IA 3B2ZA 3DWBA 3RTTA 4FXYP 1QJIA 3RTSA 4FVLA 1MMPA 4DV8A 2OXUA 3Q2HA 4H2EA 1O0QA 1G12A 1UTTA 2OW0A 3DPEA 4GR3A 3Q2GA 1XUCA 4GUYA 3HDAP 2W14A 1B8YA 1KUGA 2JT6A 1I76A 4GQLA 3G5CA 1CIZA 2WO8A 2OW2A 1K7QA 3F18A 1AF0A 4A3WA 3CKIA 1S4BP 4ILWD 4A7BA 3EWJA 1R55A 3TVCA 1BUDA 1FLSA 3HB2P 1KUIA 1JAPA 3WV3A 1J7NA 3LILA 1IAEA 2L0RA 3KECA 2AYKA 1OM7A 2V4BA 2W13A 3DL1A 5CZMA 1I73A 5CUHA 3ZXHA 1HTDA 1G49A 3DNGA 3F17A 1OM6A 4GF1A 1FBLA 1BUVM 4DF9A 4JP4A 1YQYA 3KMCA 3VTGA 1BM6A 1SRPA 5I3MA 1QIAA 1R1JA 2YB9A 3EHYA 1D8MA 2A8HA 4HX3A 4AYKA 1XFUA 2Y6DA 2AIGP 3L0VA 3VI1A 3K7NA 5D3CA 4G9LA 3N2VA 4WKEA 2JIHA 1A85A 5D1SA 3KEKA 1Y8JA 3UVCA 4HMAA 4I35A 1PWWA 1KAPP 3HDBA 1KUKA 3LE9A 2POJA 1GKDA 1MNCA 1R54A 3LIKA 2EROA 4R3VA 1XURA 5BPAA 1PWPA 3P1VA 3O64A 4AUOA 3EDZA 1XFWA 2WO9A 2FV5A 830CA 4IUWA 3LUMA 1SLMA 456CA 2E3XA 2DDFA 1D8FA 2OI0A 3I7GA 4FU4A 1IAGA 1G9KA 3DPFA 4GWNA 2RJQA 2FV9A 2MLRA 2X7MA 4H76A 2D1OA 1HFCA 1L6JA 5B5OA 1XFZA 1IABA 1PWUA 1Y93A 4FXQA 2OVZA 4PKQA 1BZSA 2OY2A 3LUNA 5H8XA 3HY7A 4JIJA 1HV5A 2Z2DA 4H3XA 1GO7P 4PKRA 3LGPA 3KWVC 3F19A 2CLTA 3LKAA 1FM1A 3GBOA 1G4KA 2OXZA 2DW2A 1CXVA 1ATLA 1ND1A 1G05A 3G42A 1RM8A 2X3AA 2JT5A 4H84A 1YP1A 2OVXA 1D5JA 4PKTA 4DD8A 1OO9A 1DMTA 1XUDA 4J4MA 1USNA 1HY7A 1CK7A 1SU3A 1UTZA 1Q3AA 1SMPA 2X3BA 1BKCE 1OM8A 1BQOA 3HBVP 5D2BA 3HBUP 1Y0VA 1K7IA 3HY9A 4WZVA 5I2ZA 1CGFA 1JAQA 3LQBA 4WKIA 1CGEA 4XM6A 1O0TA 3AYKA 1QJJA 3KEJA 2TCLA 1ZTQA 1JIWP 3O2XA 5BOTA 1BKCA 1PWVA 1JANA 3B92A 5BOYA 4L63A 3AYUA 1KBCA 2KRJA 3KRYA 2XS3A 1ASTA 4XBHA 1A86A 1UMTA 2X3CA 1XFYA 4G0DA 1KUHA 1GKCA 2MZHA 2YIGA 3LIRA 5I43A 4EFSA 4H82A 3EDGA 2O36A 2OZRA 2W15A 3NX7A 1D7XA 2N8RA 1K7GA 5D7WA 3LMCA 1OMJA 1SLNA 1GE5A 5CXAA 4GR8A 1GE6A 1BSWA 966CA 2CKIA 2RJPA 4H1QA 3DTIA 1B3DA 1QUAA 4I03A 3OHOA 1OS9A 1AKLA 4ZR5A 1IAAA 1C7KA 2O3EA 5L7FA 2JNPA 2Y6CA 5I4OA 2OW1A 4PKSA 4CTHA 4XM7A 2J83A 3F1AA 1EUBA 4L19A 1BQQM 3LJZA 4GR0A 3LQ0A 1HFSA 1MMRA 3HYGA 3WV2A 4IN9A 1YOUA 1JKYA 1CGLA 2USNA 1JIZA 4AXQA 4H30A 1EB6A 1UEAA 2K2GA 1QIBA 2JSDA 1XFVA 3EDHA 1QICA 1JJ9A 2ERPA 3DSLA 3F16A 5D1TA 4AIGA 3K7LA 1GE7A 5JMYA 2D1NA 5LABA 4QKZA 1BKCI 3N2UA 2J0TA 5L79A 1R1HA 3LJGA 4PKUA 2K9CA 3P24A 3USNA 2DDYA 3TS4A 1ZXVA 1DTHA 3DTEA 3ZUKA 1PWQA 4GWMA 2W12A 2MZIA 2DW0A 2PJTA 4JQGA 3TSKA 4JA1A 1JH1A 2I47A 1GO8P 4WF6A 4Q1LA 4PKWA 3U1RA 1MMBA 3KMEA 3LEAA 1ZP5A 4JPAA 5I12A 5B5PA 1H71P 3LK8A 1UMSA 3F15A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZXC A;  3E8R A;  1AYK A;  1BIW A;  1Z3J A;  2SRT A;  4WK7 A;  3V96 B;  1ZS0 A;  1ROS A;  3KHI A;  3MA2 A;  2OXW A;  1CAQ A;  1YCM A;  2XS4 A;  1IAC A;  3OHL A;  2MLS A;  2W0D A;  3EHX A;  4H49 A;  1KUF A;  1XFX A;  1WNI A;  2MZE A;  2QPJ A;  3ELM A;  1SAT A;  2ERQ A;  1GXD A;  1I1I P;  1OS2 A;  4ON1 A;  4XM8 A;  4PKV A;  1EAK A;  3I7I A;  2HU6 A;  3B8Z A;  1RMZ A;  1IAD A;  1ZVX A;  4L6T A;  4XCT A;  3AIG A;  4IJO A;  5I0L A;  4DPE A;  1C8T A;  1JK3 A;  3L0T A;  2DW1 A;  1JAO A;  3EDI A;  1CQR A;  3SHI A;  5D1U A;  2WOA A;  3LJT A;  3WV1 A;  2OY4 A;  3ZVS A;  1HOV A;  3TT4 A;  1C3I A;  3BA0 A;  1MMQ A;  2OW9 A;  2E2D A;  1R1I A;  3B2Z A;  3DWB A;  3RTT A;  4FXY P;  1QJI A;  3RTS A;  4FVL A;  1MMP A;  4DV8 A;  2OXU A;  3Q2H A;  4H2E A;  1O0Q A;  1G12 A;  1UTT A;  2OW0 A;  3DPE A;  4GR3 A;  3Q2G A;  1XUC A;  4GUY A;  3HDA P;  2W14 A;  1B8Y A;  1KUG A;  2JT6 A;  1I76 A;  4GQL A;  3G5C A;  1CIZ A;  2WO8 A;  2OW2 A;  1K7Q A;  3F18 A;  1AF0 A;  4A3W A;  3CKI A;  1S4B P;  4ILW D;  4A7B A;  3EWJ A;  1R55 A;  3TVC A;  1BUD A;  1FLS A;  3HB2 P;  1KUI A;  1JAP A;  3WV3 A;  1J7N A;  3LIL A;  1IAE A;  2L0R A;  3KEC A;  2AYK A;  1OM7 A;  2V4B A;  2W13 A;  3DL1 A;  5CZM A;  1I73 A;  5CUH A;  3ZXH A;  1HTD A;  1G49 A;  3DNG A;  3F17 A;  1OM6 A;  4GF1 A;  1FBL A;  1BUV M;  4DF9 A;  4JP4 A;  1YQY A;  3KMC A;  3VTG A;  1BM6 A;  1SRP A;  5I3M A;  1QIA A;  1R1J A;  2YB9 A;  3EHY A;  1D8M A;  2A8H A;  4HX3 A;  4AYK A;  1XFU A;  2Y6D A;  2AIG P;  3L0V A;  3VI1 A;  3K7N A;  5D3C A;  4G9L A;  3N2V A;  4WKE A;  2JIH A;  1A85 A;  5D1S A;  3KEK A;  1Y8J A;  3UVC A;  4HMA A;  4I35 A;  1PWW A;  1KAP P;  3HDB A;  1KUK A;  3LE9 A;  2POJ A;  1GKD A;  1MNC A;  1R54 A;  3LIK A;  2ERO A;  4R3V A;  1XUR A;  5BPA A;  1PWP A;  3P1V A;  3O64 A;  4AUO A;  3EDZ A;  1XFW A;  2WO9 A;  2FV5 A;  830C A;  4IUW A;  3LUM A;  1SLM A;  456C A;  2E3X A;  2DDF A;  1D8F A;  2OI0 A;  3I7G A;  4FU4 A;  1IAG A;  1G9K A;  3DPF A;  4GWN A;  2RJQ A;  2FV9 A;  2MLR A;  2X7M A;  4H76 A;  2D1O A;  1HFC A;  1L6J A;  5B5O A;  1XFZ A;  1IAB A;  1PWU A;  1Y93 A;  4FXQ A;  2OVZ A;  4PKQ A;  1BZS A;  2OY2 A;  3LUN A;  5H8X A;  3HY7 A;  4JIJ A;  1HV5 A;  2Z2D A;  4H3X A;  1GO7 P;  4PKR A;  3LGP A;  3KWV C;  3F19 A;  2CLT A;  3LKA A;  1FM1 A;  3GBO A;  1G4K A;  2OXZ A;  2DW2 A;  1CXV A;  1ATL A;  1ND1 A;  1G05 A;  3G42 A;  1RM8 A;  2X3A A;  2JT5 A;  4H84 A;  1YP1 A;  2OVX A;  1D5J A;  4PKT A;  4DD8 A;  1OO9 A;  1DMT A;  1XUD A;  4J4M A;  1USN A;  1HY7 A;  1CK7 A;  1SU3 A;  1UTZ A;  1Q3A A;  1SMP A;  2X3B A;  1BKC E;  1OM8 A;  1BQO A;  3HBV P;  5D2B A;  3HBU P;  1Y0V A;  1K7I A;  3HY9 A;  4WZV A;  5I2Z A;  1CGF A;  1JAQ A;  3LQB A;  4WKI A;  1CGE A;  4XM6 A;  1O0T A;  3AYK A;  1QJJ A;  3KEJ A;  2TCL A;  1ZTQ A;  1JIW P;  3O2X A;  5BOT A;  1BKC A;  1PWV A;  1JAN A;  3B92 A;  5BOY A;  4L63 A;  3AYU A;  1KBC A;  2KRJ A;  3KRY A;  2XS3 A;  1AST A;  4XBH A;  1A86 A;  1UMT A;  2X3C A;  1XFY A;  4G0D A;  1KUH A;  1GKC A;  2MZH A;  2YIG A;  3LIR A;  5I43 A;  4EFS A;  4H82 A;  3EDG A;  2O36 A;  2OZR A;  2W15 A;  3NX7 A;  1D7X A;  2N8R A;  1K7G A;  5D7W A;  3LMC A;  1OMJ A;  1SLN A;  1GE5 A;  5CXA A;  4GR8 A;  1GE6 A;  1BSW A;  966C A;  2CKI A;  2RJP A;  4H1Q A;  1B3D A;  1QUA A;  4I03 A;  3OHO A;  1OS9 A;  1AKL A;  4ZR5 A;  1IAA A;  1C7K A;  2O3E A;  5L7F A;  2JNP A;  2Y6C A;  5I4O A;  2OW1 A;  4PKS A;  4CTH A;  4XM7 A;  2J83 A;  3F1A A;  1EUB A;  4L19 A;  1BQQ M;  3LJZ A;  4GR0 A;  3LQ0 A;  1HFS A;  1MMR A;  3HYG A;  3WV2 A;  4IN9 A;  1YOU A;  1JKY A;  1CGL A;  2USN A;  1JIZ A;  4AXQ A;  4H30 A;  1EB6 A;  1UEA A;  2K2G A;  1QIB A;  2JSD A;  1XFV A;  3EDH A;  1QIC A;  1JJ9 A;  2ERP A;  3DSL A;  3F16 A;  5D1T A;  4AIG A;  3K7L A;  1GE7 A;  5JMY A;  2D1N A;  5LAB A;  4QKZ A;  1BKC I;  3N2U A;  2J0T A;  5L79 A;  1R1H A;  3LJG A;  4PKU A;  2K9C A;  3P24 A;  3USN A;  2DDY A;  3TS4 A;  1ZXV A;  1DTH A;  3ZUK A;  1PWQ A;  4GWM A;  2W12 A;  2MZI A;  2DW0 A;  2PJT A;  4JQG A;  3TSK A;  4JA1 A;  1JH1 A;  2I47 A;  1GO8 P;  4WF6 A;  4Q1L A;  4PKW A;  3U1R A;  1MMB A;  3KME A;  3LEA A;  1ZP5 A;  4JPA A;  5I12 A;  5B5P A;  1H71 P;  3LK8 A;  1UMS A;  3F15 A; 
#chains in the Genus database with same CATH topology
 1ZXC A;  3E8R A;  1AYK A;  1BIW A;  1Z3J A;  2SRT A;  4WK7 A;  3V96 B;  1ZS0 A;  1ROS A;  3KHI A;  3MA2 A;  2OXW A;  1CAQ A;  1YCM A;  2XS4 A;  1IAC A;  3OHL A;  2MLS A;  2W0D A;  3EHX A;  4H49 A;  1KUF A;  1XFX A;  1WNI A;  2MZE A;  2QPJ A;  3ELM A;  1SAT A;  2ERQ A;  1GXD A;  1I1I P;  1OS2 A;  4ON1 A;  4XM8 A;  4PKV A;  1EAK A;  3I7I A;  2HU6 A;  3B8Z A;  1RMZ A;  1IAD A;  1ZVX A;  4L6T A;  4XCT A;  3DTK A;  2YUF A;  3AIG A;  4IJO A;  5I0L A;  4DPE A;  1C8T A;  1JK3 A;  3L0T A;  2DW1 A;  1JAO A;  3EDI A;  4L7A A;  1CQR A;  3SHI A;  5D1U A;  2WOA A;  3LJT A;  3WV1 A;  2OY4 A;  3ZVS A;  1HOV A;  3TT4 A;  1C3I A;  3BA0 A;  1MMQ A;  2OW9 A;  2E2D A;  1R1I A;  3B2Z A;  3DWB A;  3RTT A;  4FXY P;  1QJI A;  3RTS A;  4FVL A;  1MMP A;  4DV8 A;  2OXU A;  3Q2H A;  4H2E A;  1O0Q A;  1G12 A;  1UTT A;  2OW0 A;  3DPE A;  4GR3 A;  3Q2G A;  1XUC A;  4GUY A;  3HDA P;  2W14 A;  1B8Y A;  1KUG A;  2JT6 A;  1I76 A;  4GQL A;  3G5C A;  1CIZ A;  2WO8 A;  2OW2 A;  1K7Q A;  3F18 A;  1AF0 A;  4A3W A;  3CKI A;  1S4B P;  4ILW D;  4A7B A;  3EWJ A;  1R55 A;  3TVC A;  1BUD A;  1FLS A;  3HB2 P;  1KUI A;  1JAP A;  1TVI A;  3WV3 A;  1J7N A;  3LIL A;  1IAE A;  2L0R A;  3KEC A;  2AYK A;  1OM7 A;  2V4B A;  2W13 A;  3DL1 A;  5CZM A;  1I73 A;  5CUH A;  3ZXH A;  1HTD A;  1G49 A;  3DNG A;  3F17 A;  1OM6 A;  4GF1 A;  1FBL A;  1BUV M;  4DF9 A;  4JP4 A;  1YQY A;  3KMC A;  3VTG A;  1BM6 A;  1SRP A;  5I3M A;  1QIA A;  1R1J A;  2YB9 A;  3EHY A;  1D8M A;  2A8H A;  4HX3 A;  4AYK A;  1XFU A;  2Y6D A;  2AIG P;  3L0V A;  3VI1 A;  3K7N A;  5D3C A;  1XAX A;  4G9L A;  3N2V A;  4WKE A;  2JIH A;  1A85 A;  5D1S A;  3KEK A;  1Y8J A;  3UVC A;  4HMA A;  4I35 A;  1PWW A;  1KAP P;  3HDB A;  1KUK A;  3LE9 A;  2POJ A;  1GKD A;  1MNC A;  1R54 A;  3LIK A;  2ERO A;  4R3V A;  1XUR A;  5BPA A;  1PWP A;  3P1V A;  3O64 A;  4AUO A;  3EDZ A;  1XFW A;  2WO9 A;  2FV5 A;  830C A;  4IUW A;  3LUM A;  1SLM A;  456C A;  2E3X A;  2DDF A;  1D8F A;  2OI0 A;  3I7G A;  4FU4 A;  1IAG A;  1G9K A;  3DPF A;  4GWN A;  2RJQ A;  2FV9 A;  2MLR A;  2X7M A;  4H76 A;  2D1O A;  1HFC A;  1L6J A;  5B5O A;  1XFZ A;  1IAB A;  1PWU A;  1Y93 A;  4FXQ A;  2OVZ A;  4PKQ A;  1BZS A;  2OY2 A;  3LUN A;  5H8X A;  3HY7 A;  4JIJ A;  1HV5 A;  2Z2D A;  4H3X A;  1GO7 P;  4PKR A;  3LGP A;  3KWV C;  3F19 A;  2CLT A;  3LKA A;  1FM1 A;  3GBO A;  1G4K A;  2OXZ A;  2DW2 A;  1CXV A;  1ATL A;  1ND1 A;  1G05 A;  3G42 A;  1RM8 A;  2X3A A;  2JT5 A;  4H84 A;  1YP1 A;  2OVX A;  1D5J A;  4PKT A;  4DD8 A;  1OO9 A;  1DMT A;  1XUD A;  4J4M A;  1USN A;  1HY7 A;  1CK7 A;  1SU3 A;  1UTZ A;  1Q3A A;  1SMP A;  2X3B A;  1BKC E;  1OM8 A;  1BQO A;  3HBV P;  1XM5 A;  5D2B A;  3HBU P;  1Y0V A;  1K7I A;  3HY9 A;  4WZV A;  5I2Z A;  1CGF A;  1JAQ A;  3LQB A;  4WKI A;  1CGE A;  4XM6 A;  1O0T A;  3AYK A;  1QJJ A;  3KEJ A;  2TCL A;  1ZTQ A;  1JIW P;  3O2X A;  5BOT A;  1BKC A;  1PWV A;  1JAN A;  3B92 A;  5BOY A;  4L63 A;  3AYU A;  1KBC A;  2KRJ A;  3KRY A;  2XS3 A;  1AST A;  4XBH A;  1A86 A;  1UMT A;  2X3C A;  1XFY A;  4G0D A;  1KUH A;  1GKC A;  2MZH A;  2YIG A;  3LIR A;  5I43 A;  4EFS A;  4H82 A;  3EDG A;  2O36 A;  2OZR A;  2W15 A;  3NX7 A;  1D7X A;  2N8R A;  1K7G A;  5D7W A;  3LMC A;  1OMJ A;  1SLN A;  1GE5 A;  5CXA A;  4GR8 A;  1GE6 A;  1BSW A;  966C A;  2CKI A;  2RJP A;  4H1Q A;  3DTI A;  1B3D A;  1QUA A;  4I03 A;  3OHO A;  1OS9 A;  1AKL A;  4ZR5 A;  1IAA A;  1C7K A;  2O3E A;  5L7F A;  2JNP A;  2Y6C A;  5I4O A;  2OW1 A;  4PKS A;  4CTH A;  4XM7 A;  2J83 A;  3F1A A;  1EUB A;  4L19 A;  1BQQ M;  3LJZ A;  4GR0 A;  3LQ0 A;  1HFS A;  1MMR A;  3HYG A;  3WV2 A;  4IN9 A;  1YOU A;  1JKY A;  1CGL A;  2USN A;  1JIZ A;  4AXQ A;  4H30 A;  1EB6 A;  1UEA A;  2K2G A;  1QIB A;  2JSD A;  1XFV A;  3EDH A;  1QIC A;  1JJ9 A;  2ERP A;  3DSL A;  3F16 A;  5D1T A;  4AIG A;  3K7L A;  1GE7 A;  5JMY A;  2D1N A;  5LAB A;  4QKZ A;  1BKC I;  3N2U A;  2J0T A;  5L79 A;  1R1H A;  3LJG A;  4PKU A;  2K9C A;  3P24 A;  3USN A;  2DDY A;  3TS4 A;  1ZXV A;  1DTH A;  3DTE A;  3ZUK A;  1PWQ A;  4GWM A;  2W12 A;  2MZI A;  2DW0 A;  2PJT A;  4JQG A;  3TSK A;  4JA1 A;  1JH1 A;  2I47 A;  1GO8 P;  4WF6 A;  4Q1L A;  4PKW A;  3U1R A;  1MMB A;  3KME A;  3LEA A;  1ZP5 A;  4JPA A;  5I12 A;  5B5P A;  1H71 P;  3LK8 A;  1UMS A;  3F15 A;  1OZ9 A; 
#chains in the Genus database with same CATH homology
 1ZXC A;  3E8R A;  1AYK A;  1BIW A;  1Z3J A;  2SRT A;  4WK7 A;  3V96 B;  1ZS0 A;  1ROS A;  3KHI A;  3MA2 A;  2OXW A;  1CAQ A;  1YCM A;  2XS4 A;  1IAC A;  3OHL A;  2MLS A;  2W0D A;  3EHX A;  4H49 A;  1KUF A;  1XFX A;  1WNI A;  2MZE A;  2QPJ A;  3ELM A;  1SAT A;  2ERQ A;  1GXD A;  1I1I P;  1OS2 A;  4ON1 A;  4XM8 A;  4PKV A;  1EAK A;  3I7I A;  2HU6 A;  3B8Z A;  1RMZ A;  1IAD A;  1ZVX A;  4L6T A;  4XCT A;  3DTK A;  2YUF A;  3AIG A;  4IJO A;  5I0L A;  4DPE A;  1C8T A;  1JK3 A;  3L0T A;  2DW1 A;  1JAO A;  3EDI A;  4L7A A;  1CQR A;  3SHI A;  5D1U A;  2WOA A;  3LJT A;  3WV1 A;  2OY4 A;  3ZVS A;  1HOV A;  3TT4 A;  1C3I A;  3BA0 A;  1MMQ A;  2OW9 A;  2E2D A;  1R1I A;  3B2Z A;  3DWB A;  3RTT A;  4FXY P;  1QJI A;  3RTS A;  4FVL A;  1MMP A;  4DV8 A;  2OXU A;  3Q2H A;  4H2E A;  1O0Q A;  1G12 A;  1UTT A;  2OW0 A;  3DPE A;  4GR3 A;  3Q2G A;  1XUC A;  4GUY A;  3HDA P;  2W14 A;  1B8Y A;  1KUG A;  2JT6 A;  1I76 A;  4GQL A;  3G5C A;  1CIZ A;  2WO8 A;  2OW2 A;  1K7Q A;  3F18 A;  1AF0 A;  4A3W A;  3CKI A;  1S4B P;  4ILW D;  4A7B A;  3EWJ A;  1R55 A;  3TVC A;  1BUD A;  1FLS A;  3HB2 P;  1KUI A;  1JAP A;  3WV3 A;  1J7N A;  3LIL A;  1IAE A;  2L0R A;  3KEC A;  2AYK A;  1OM7 A;  2V4B A;  2W13 A;  3DL1 A;  5CZM A;  1I73 A;  5CUH A;  3ZXH A;  1HTD A;  1G49 A;  3DNG A;  3F17 A;  1OM6 A;  4GF1 A;  1FBL A;  1BUV M;  4DF9 A;  4JP4 A;  1YQY A;  3KMC A;  3VTG A;  1BM6 A;  1SRP A;  5I3M A;  1QIA A;  1R1J A;  2YB9 A;  3EHY A;  1D8M A;  2A8H A;  4HX3 A;  4AYK A;  1XFU A;  2Y6D A;  2AIG P;  3L0V A;  3VI1 A;  3K7N A;  5D3C A;  4G9L A;  3N2V A;  4WKE A;  2JIH A;  1A85 A;  5D1S A;  3KEK A;  1Y8J A;  3UVC A;  4HMA A;  4I35 A;  1PWW A;  1KAP P;  3HDB A;  1KUK A;  3LE9 A;  2POJ A;  1GKD A;  1MNC A;  1R54 A;  3LIK A;  2ERO A;  4R3V A;  1XUR A;  5BPA A;  1PWP A;  3P1V A;  3O64 A;  4AUO A;  3EDZ A;  1XFW A;  2WO9 A;  2FV5 A;  830C A;  4IUW A;  3LUM A;  1SLM A;  456C A;  2E3X A;  2DDF A;  1D8F A;  2OI0 A;  3I7G A;  4FU4 A;  1IAG A;  1G9K A;  3DPF A;  4GWN A;  2RJQ A;  2FV9 A;  2MLR A;  2X7M A;  4H76 A;  2D1O A;  1HFC A;  1L6J A;  5B5O A;  1XFZ A;  1IAB A;  1PWU A;  1Y93 A;  4FXQ A;  2OVZ A;  4PKQ A;  1BZS A;  2OY2 A;  3LUN A;  5H8X A;  3HY7 A;  4JIJ A;  1HV5 A;  2Z2D A;  4H3X A;  1GO7 P;  4PKR A;  3LGP A;  3KWV C;  3F19 A;  2CLT A;  3LKA A;  1FM1 A;  3GBO A;  1G4K A;  2OXZ A;  2DW2 A;  1CXV A;  1ATL A;  1ND1 A;  1G05 A;  3G42 A;  1RM8 A;  2X3A A;  2JT5 A;  4H84 A;  1YP1 A;  2OVX A;  1D5J A;  4PKT A;  4DD8 A;  1OO9 A;  1DMT A;  1XUD A;  4J4M A;  1USN A;  1HY7 A;  1CK7 A;  1SU3 A;  1UTZ A;  1Q3A A;  1SMP A;  2X3B A;  1BKC E;  1OM8 A;  1BQO A;  3HBV P;  5D2B A;  3HBU P;  1Y0V A;  1K7I A;  3HY9 A;  4WZV A;  5I2Z A;  1CGF A;  1JAQ A;  3LQB A;  4WKI A;  1CGE A;  4XM6 A;  1O0T A;  3AYK A;  1QJJ A;  3KEJ A;  2TCL A;  1ZTQ A;  1JIW P;  3O2X A;  5BOT A;  1BKC A;  1PWV A;  1JAN A;  3B92 A;  5BOY A;  4L63 A;  3AYU A;  1KBC A;  2KRJ A;  3KRY A;  2XS3 A;  1AST A;  4XBH A;  1A86 A;  1UMT A;  2X3C A;  1XFY A;  4G0D A;  1KUH A;  1GKC A;  2MZH A;  2YIG A;  3LIR A;  5I43 A;  4EFS A;  4H82 A;  3EDG A;  2O36 A;  2OZR A;  2W15 A;  3NX7 A;  1D7X A;  2N8R A;  1K7G A;  5D7W A;  3LMC A;  1OMJ A;  1SLN A;  1GE5 A;  5CXA A;  4GR8 A;  1GE6 A;  1BSW A;  966C A;  2CKI A;  2RJP A;  4H1Q A;  3DTI A;  1B3D A;  1QUA A;  4I03 A;  3OHO A;  1OS9 A;  1AKL A;  4ZR5 A;  1IAA A;  1C7K A;  2O3E A;  5L7F A;  2JNP A;  2Y6C A;  5I4O A;  2OW1 A;  4PKS A;  4CTH A;  4XM7 A;  2J83 A;  3F1A A;  1EUB A;  4L19 A;  1BQQ M;  3LJZ A;  4GR0 A;  3LQ0 A;  1HFS A;  1MMR A;  3HYG A;  3WV2 A;  4IN9 A;  1YOU A;  1JKY A;  1CGL A;  2USN A;  1JIZ A;  4AXQ A;  4H30 A;  1EB6 A;  1UEA A;  2K2G A;  1QIB A;  2JSD A;  1XFV A;  3EDH A;  1QIC A;  1JJ9 A;  2ERP A;  3DSL A;  3F16 A;  5D1T A;  4AIG A;  3K7L A;  1GE7 A;  5JMY A;  2D1N A;  5LAB A;  4QKZ A;  1BKC I;  3N2U A;  2J0T A;  5L79 A;  1R1H A;  3LJG A;  4PKU A;  2K9C A;  3P24 A;  3USN A;  2DDY A;  3TS4 A;  1ZXV A;  1DTH A;  3DTE A;  3ZUK A;  1PWQ A;  4GWM A;  2W12 A;  2MZI A;  2DW0 A;  2PJT A;  4JQG A;  3TSK A;  4JA1 A;  1JH1 A;  2I47 A;  1GO8 P;  4WF6 A;  4Q1L A;  4PKW A;  3U1R A;  1MMB A;  3KME A;  3LEA A;  1ZP5 A;  4JPA A;  5I12 A;  5B5P A;  1H71 P;  3LK8 A;  1UMS A;  3F15 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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