2YIGA

Mmp13 in complex with a novel selective non zinc binding inhibitor
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
169
structure length
167
Chain Sequence
YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKFMLPDDDVQGIQSLYGPGDED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Selective Non Zinc Binding Inhibitors of Mmp13.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords COLLAGENASE 3
total genus 46
structure length 167
sequence length 169
chains with identical sequence B
ec nomenclature ec 3.4.24.-:
pdb deposition date 2011-05-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 2yigA00
1KUIA 5D1TA 2W14A 2OW0A 1SATA 3E8RA 4JP4A 1KUFA 3V96B 1BM6A 1G9KA 2K2GA 1KUGA 1L6JA 1CAQA 3LJZA 5CUHA 3ZUKA 1IADA 2V4BA 3KRYA 2WO8A 1SLNA 1XFVA 2MZHA 1BIWA 1ZXVA 2W12A 4HMAA 2K9CA 3K7NA 2D1NA 4Q1LA 1PWQA 1Y8JA 2I47A 2OW2A 2OI0A 1XUCA 3DWBA 1Q3AA 1KAPP 456CA 3HB2P 3KHIA 4FXYP 5I2ZA 4L19A 2MLSA 1XURA 4PKRA 4IN9A 2JT5A 1JAPA 3AIGA 3LJGA 1BKCI 1OMJA 3NX7A 3USNA 3LUNA 3O2XA 1K7GA 4AUOA 3KEKA 1R1IA 1YOUA 2CKIA 4GF1A 3I7GA 3HBUP 3I7IA 1WNIA 4A7BA 1HFCA 1R55A 1UMSA 3F19A 2J83A 1CGFA 3HY7A 4PKSA 5JMYA 3MA2A 1BSWA 1GKCA 1OM8A 1GE6A 4GR3A 4FVLA 1ATLA 1R1HA 2OXWA 3LIKA 1CQRA 3LILA 1QUAA 1FLSA 1G12A 1BQOA 4DF9A 2TCLA 3OHOA 1EB6A 1C8TA 2AYKA 2MZEA 3HBVP 4R3VA 2J0TA 1I76A 1XFZA 4XM7A 2JNPA 4H30A 1UEAA 1A86A 3EHXA 4WF6A 1D8FA 3HDAP 1XFYA 1GE5A 1YCMA 4JQGA 2XS4A 3EDGA 3B92A 1MMRA 5I43A 5L7FA 2OZRA 3DSLA 5BOTA 5D3CA 4ON1A 2DW2A 1IACA 4JA1A 3ELMA 5B5OA 3LIRA 3EWJA 1OM7A 5D1SA 2O36A 1KUHA 4PKQA 1EUBA 1O0TA 3DNGA 3F17A 4WK7A 1JK3A 1MMBA 2HU6A 4AXQA 1UTZA 1ZVXA 1BQQM 1FM1A 2E3XA 1CXVA 3LE9A 1ASTA 1ZTQA 3F1AA 3RTSA 3EHYA 3AYKA 1B3DA 1JAOA 1CIZA 3GBOA 4JPAA 1GKDA 3TSKA 2ERQA 3LGPA 4GUYA 1JAQA 1G05A 1O0QA 1K7IA 1USNA 830CA 1ZP5A 1AKLA 3TT4A 3WV2A 2E2DA 2JIHA 1UMTA 3U1RA 1GE7A 1K7QA 1HOVA 1R1JA 2KRJA 1BUDA 1KBCA 3F15A 1OS9A 1GO7P 2X3BA 4J4MA 2WO9A 4PKTA 1XFWA 3CKIA 2X3AA 4H2EA 1I73A 3ZVSA 1J7NA 1BKCE 4ZR5A 3B8ZA 1ROSA 2W13A 3Q2HA 5D2BA 1YQYA 2RJPA 2FV9A 3KMEA 3TS4A 4H1QA 1PWVA 4WZVA 5D7WA 4GR8A 3KMCA 3LQBA 1XFXA 1A85A 3TVCA 4XM6A 1SRPA 1Y93A 4ILWD 2POJA 3WV1A 1IAEA 2OVXA 3HDBA 1JIZA 3P24A 1DTHA 3P1VA 2DDFA 5CZMA 2DW0A 1Z3JA 4H76A 1BKCA 4XBHA 3EDHA 1YP1A 1IAAA 1SMPA 4JIJA 4PKUA 1PWWA 4PKWA 1JH1A 1QIBA 1C7KA 5CXAA 3LQ0A 5I0LA 3G42A 1UTTA 3VTGA 4IUWA 3N2VA 1CK7A 1D5JA 4H49A 4AIGA 4FXQA 3DPFA 4WKEA 2OVZA 1JJ9A 4XM8A 2OW9A 1JIWP 3O64A 2EROA 4A3WA 1QICA 4DD8A 1C3IA 2MLRA 2W15A 2N8RA 1QJIA 5D1UA 2PJTA 4I35A 3VI1A 2MZIA 3Q2GA 1ND1A 2OY2A 1XFUA 2QPJA 2XS3A 1Y0VA 1ZXCA 5B5PA 2Y6CA 1PWPA 4CTHA 1RM8A 4H82A 1PWUA 4H84A 2DDYA 966CA 2A8HA 3DPEA 4QKZA 1AYKA 3HY9A 2W0DA 2JT6A 3RTTA 3LJTA 4GWNA 1QIAA 3F16A 1D7XA 3F18A 3N2UA 1EAKA 5L79A 4DPEA 1GXDA 1QJJA 3KEJA 2WOAA 5BOYA 1SLMA 1IAGA 4G0DA 1MMQA 1HY7A 3LEAA 3WV3A 3KECA 3ZXHA 4DV8A 2YB9A 1CGEA 2X3CA 1GO8P 4GWMA 1KUKA 4IJOA 3K7LA 2OXZA 4XCTA 3SHIA 2CLTA 2OXUA 1RMZA 5LABA 3UVCA 1S4BP 2OW1A 1G4KA 2USNA 1I1IP 3L0TA 4AYKA 5I3MA 3LK8A 5I4OA 1B8YA 1OS2A 1XUDA 2ERPA 3EDIA 5I12A 1HV5A 1H71P 1R54A 1BZSA 1HTDA 2Y6DA 2FV5A 3HYGA 3G5CA 4PKVA 1BUVM 3L0VA 4HX3A 4WKIA 1IABA 1JKYA 4L63A 1D8MA 2OY4A 2SRTA 1SU3A 2JSDA 2AIGP 1MMPA 2X7MA 1CGLA 1JANA 4I03A 3DL1A 2YIGA 4EFSA 2DW1A 4G9LA 1OO9A 3KWVC 1OM6A 4L6TA 2D1OA 4H3XA 3BA0A 2L0RA 3AYUA 2RJQA 5H8XA 1FBLA 1ZS0A 3OHLA 2Z2DA 3LUMA 4FU4A 1HFSA 3LKAA 5BPAA 3EDZA 3LMCA 1DMTA 1AF0A 1MNCA 3B2ZA 4GR0A 1G49A 4GQLA 2O3EA
chains in the Genus database with same CATH superfamily
1XM5A 1KUIA 5D1TA 2W14A 2OW0A 1SATA 3E8RA 4JP4A 1KUFA 3V96B 1BM6A 1G9KA 2K2GA 1KUGA 1L6JA 1CAQA 3LJZA 5CUHA 3ZUKA 1IADA 2V4BA 3KRYA 2WO8A 1SLNA 1XFVA 2MZHA 1BIWA 1ZXVA 2W12A 4HMAA 2K9CA 3K7NA 2D1NA 4Q1LA 1PWQA 1Y8JA 2I47A 2OW2A 2OI0A 1XUCA 3DWBA 1Q3AA 1KAPP 456CA 3HB2P 3KHIA 4FXYP 5I2ZA 4L19A 2MLSA 1XURA 4PKRA 1XAXA 4IN9A 2JT5A 1JAPA 3AIGA 3LJGA 1BKCI 1OMJA 3NX7A 3USNA 3DTIA 3LUNA 3O2XA 1K7GA 4AUOA 3KEKA 1R1IA 1YOUA 2CKIA 4GF1A 3I7GA 3HBUP 3I7IA 1WNIA 4A7BA 1HFCA 1R55A 1UMSA 3F19A 2J83A 1CGFA 3HY7A 4PKSA 5JMYA 3MA2A 1BSWA 1GKCA 1OM8A 1GE6A 4GR3A 4FVLA 1ATLA 1R1HA 2OXWA 3LIKA 1CQRA 3LILA 1QUAA 1FLSA 1G12A 1BQOA 4DF9A 2TCLA 3OHOA 1EB6A 1C8TA 2AYKA 2MZEA 3HBVP 4R3VA 2J0TA 1I76A 1XFZA 4XM7A 2JNPA 4H30A 1UEAA 1A86A 3EHXA 4WF6A 1D8FA 3HDAP 1XFYA 1GE5A 1YCMA 4JQGA 2XS4A 3EDGA 3B92A 1MMRA 5I43A 5L7FA 2OZRA 3DSLA 5BOTA 5D3CA 4ON1A 2DW2A 1IACA 4JA1A 3ELMA 5B5OA 3LIRA 3EWJA 1OM7A 5D1SA 2O36A 1KUHA 4PKQA 1EUBA 1O0TA 3DNGA 3F17A 4WK7A 1JK3A 1MMBA 2HU6A 4AXQA 1UTZA 1ZVXA 1BQQM 1FM1A 2E3XA 1CXVA 3LE9A 1ASTA 1ZTQA 3F1AA 3RTSA 3EHYA 3AYKA 1B3DA 1JAOA 1CIZA 3GBOA 4JPAA 1GKDA 3TSKA 2ERQA 3LGPA 4GUYA 1JAQA 1G05A 1O0QA 1K7IA 1USNA 830CA 1ZP5A 1AKLA 3TT4A 3WV2A 2E2DA 2JIHA 1UMTA 3U1RA 1GE7A 1K7QA 1HOVA 1R1JA 2KRJA 1BUDA 1KBCA 3F15A 1OS9A 1GO7P 2X3BA 4J4MA 2WO9A 4PKTA 1XFWA 3CKIA 2X3AA 4H2EA 1I73A 3ZVSA 1J7NA 1BKCE 4ZR5A 3B8ZA 1ROSA 2W13A 3Q2HA 5D2BA 1YQYA 2RJPA 2FV9A 3KMEA 3TS4A 4H1QA 1PWVA 4WZVA 5D7WA 4GR8A 3KMCA 3LQBA 1XFXA 1A85A 3TVCA 4XM6A 1SRPA 1Y93A 4ILWD 3DTKA 2POJA 3WV1A 1IAEA 2OVXA 3HDBA 1JIZA 3P24A 1DTHA 3P1VA 2DDFA 5CZMA 2DW0A 1Z3JA 4H76A 1BKCA 4XBHA 3EDHA 1YP1A 1IAAA 1SMPA 4JIJA 4PKUA 1PWWA 4PKWA 1JH1A 1QIBA 1C7KA 5CXAA 3LQ0A 5I0LA 3G42A 1UTTA 3VTGA 4IUWA 3N2VA 1CK7A 1D5JA 4H49A 4AIGA 4FXQA 3DPFA 4WKEA 2OVZA 1JJ9A 4XM8A 2OW9A 1JIWP 3O64A 2EROA 4A3WA 1QICA 4DD8A 1C3IA 2MLRA 1OZ9A 2W15A 2N8RA 1QJIA 5D1UA 2PJTA 4I35A 3VI1A 2MZIA 3Q2GA 1ND1A 2OY2A 1XFUA 2QPJA 2XS3A 1Y0VA 1ZXCA 5B5PA 2Y6CA 1PWPA 4CTHA 1RM8A 4H82A 1PWUA 4H84A 2DDYA 966CA 2A8HA 3DPEA 4QKZA 1AYKA 3HY9A 2W0DA 2JT6A 3RTTA 3LJTA 4GWNA 1TVIA 1QIAA 3F16A 1D7XA 3F18A 3N2UA 1EAKA 5L79A 4DPEA 1GXDA 1QJJA 3KEJA 2WOAA 5BOYA 3DTEA 1SLMA 1IAGA 4G0DA 1MMQA 1HY7A 3LEAA 3WV3A 3KECA 3ZXHA 4DV8A 2YB9A 1CGEA 2X3CA 1GO8P 4GWMA 1KUKA 4IJOA 3K7LA 2OXZA 4XCTA 3SHIA 2CLTA 2OXUA 1RMZA 5LABA 3UVCA 1S4BP 2OW1A 1G4KA 2USNA 1I1IP 3L0TA 4AYKA 5I3MA 3LK8A 5I4OA 1B8YA 1OS2A 1XUDA 2ERPA 3EDIA 5I12A 1HV5A 1H71P 1R54A 1BZSA 1HTDA 2Y6DA 2FV5A 3HYGA 3G5CA 4PKVA 1BUVM 3L0VA 4HX3A 4WKIA 1IABA 1JKYA 4L63A 1D8MA 2OY4A 2SRTA 1SU3A 2JSDA 2AIGP 1MMPA 2X7MA 1CGLA 1JANA 4I03A 3DL1A 2YIGA 4EFSA 2DW1A 4G9LA 1OO9A 4L7AA 3KWVC 1OM6A 4L6TA 2D1OA 4H3XA 3BA0A 2L0RA 3AYUA 2RJQA 5H8XA 1FBLA 1ZS0A 3OHLA 2Z2DA 3LUMA 4FU4A 2YUFA 1HFSA 3LKAA 5BPAA 3EDZA 3LMCA 1DMTA 1AF0A 1MNCA 3B2ZA 4GR0A 1G49A 4GQLA 2O3EA
chains in the Genus database with same CATH topology
1KUIA 5D1TA 2W14A 2OW0A 1SATA 3E8RA 4JP4A 1KUFA 3V96B 1BM6A 1G9KA 2K2GA 1KUGA 1L6JA 1CAQA 3LJZA 5CUHA 3ZUKA 1IADA 2V4BA 3KRYA 2WO8A 1SLNA 1XFVA 2MZHA 1BIWA 1ZXVA 2W12A 4HMAA 2K9CA 3K7NA 2D1NA 4Q1LA 1PWQA 1Y8JA 2I47A 2OW2A 2OI0A 1XUCA 3DWBA 1Q3AA 1KAPP 456CA 3HB2P 3KHIA 4FXYP 5I2ZA 4L19A 2MLSA 1XURA 4PKRA 4IN9A 2JT5A 1JAPA 3AIGA 3LJGA 1BKCI 1OMJA 3NX7A 3USNA 3DTIA 3LUNA 3O2XA 1K7GA 4AUOA 3KEKA 1R1IA 1YOUA 2CKIA 4GF1A 3I7GA 3HBUP 3I7IA 1WNIA 4A7BA 1HFCA 1R55A 1UMSA 3F19A 2J83A 1CGFA 3HY7A 4PKSA 5JMYA 3MA2A 1BSWA 1GKCA 1OM8A 1GE6A 4GR3A 4FVLA 1ATLA 1R1HA 2OXWA 3LIKA 1CQRA 3LILA 1QUAA 1FLSA 1G12A 1BQOA 4DF9A 2TCLA 3OHOA 1EB6A 1C8TA 2AYKA 2MZEA 3HBVP 4R3VA 2J0TA 1I76A 1XFZA 4XM7A 2JNPA 4H30A 1UEAA 1A86A 3EHXA 4WF6A 1D8FA 3HDAP 1XFYA 1GE5A 1YCMA 4JQGA 2XS4A 3EDGA 3B92A 1MMRA 5I43A 5L7FA 2OZRA 3DSLA 5BOTA 5D3CA 4ON1A 2DW2A 1IACA 4JA1A 3ELMA 5B5OA 3LIRA 3EWJA 1OM7A 5D1SA 2O36A 1KUHA 4PKQA 1EUBA 1O0TA 3DNGA 3F17A 4WK7A 1JK3A 1MMBA 2HU6A 4AXQA 1UTZA 1ZVXA 1BQQM 1FM1A 2E3XA 1CXVA 3LE9A 1ASTA 1ZTQA 3F1AA 3RTSA 3EHYA 3AYKA 1B3DA 1JAOA 1CIZA 3GBOA 4JPAA 1GKDA 3TSKA 2ERQA 3LGPA 4GUYA 1JAQA 1G05A 1O0QA 1K7IA 1USNA 830CA 1ZP5A 1AKLA 3TT4A 3WV2A 2E2DA 2JIHA 1UMTA 3U1RA 1GE7A 1K7QA 1HOVA 1R1JA 2KRJA 1BUDA 1KBCA 3F15A 1OS9A 1GO7P 2X3BA 4J4MA 2WO9A 4PKTA 1XFWA 3CKIA 2X3AA 4H2EA 1I73A 3ZVSA 1J7NA 1BKCE 4ZR5A 3B8ZA 1ROSA 2W13A 3Q2HA 5D2BA 1YQYA 2RJPA 2FV9A 3KMEA 3TS4A 4H1QA 1PWVA 4WZVA 5D7WA 4GR8A 3KMCA 3LQBA 1XFXA 1A85A 3TVCA 4XM6A 1SRPA 1Y93A 4ILWD 3DTKA 2POJA 3WV1A 1IAEA 2OVXA 3HDBA 1JIZA 3P24A 1DTHA 3P1VA 2DDFA 5CZMA 2DW0A 1Z3JA 4H76A 1BKCA 4XBHA 3EDHA 1YP1A 1IAAA 1SMPA 4JIJA 4PKUA 1PWWA 4PKWA 1JH1A 1QIBA 1C7KA 5CXAA 3LQ0A 5I0LA 3G42A 1UTTA 3VTGA 4IUWA 3N2VA 1CK7A 1D5JA 4H49A 4AIGA 4FXQA 3DPFA 4WKEA 2OVZA 1JJ9A 4XM8A 2OW9A 1JIWP 3O64A 2EROA 4A3WA 1QICA 4DD8A 1C3IA 2MLRA 2W15A 2N8RA 1QJIA 5D1UA 2PJTA 4I35A 3VI1A 2MZIA 3Q2GA 1ND1A 2OY2A 1XFUA 2QPJA 2XS3A 1Y0VA 1ZXCA 5B5PA 2Y6CA 1PWPA 4CTHA 1RM8A 4H82A 1PWUA 4H84A 2DDYA 966CA 2A8HA 3DPEA 4QKZA 1AYKA 3HY9A 2W0DA 2JT6A 3RTTA 3LJTA 4GWNA 1QIAA 3F16A 1D7XA 3F18A 3N2UA 1EAKA 5L79A 4DPEA 1GXDA 1QJJA 3KEJA 2WOAA 5BOYA 3DTEA 1SLMA 1IAGA 4G0DA 1MMQA 1HY7A 3LEAA 3WV3A 3KECA 3ZXHA 4DV8A 2YB9A 1CGEA 2X3CA 1GO8P 4GWMA 1KUKA 4IJOA 3K7LA 2OXZA 4XCTA 3SHIA 2CLTA 2OXUA 1RMZA 5LABA 3UVCA 1S4BP 2OW1A 1G4KA 2USNA 1I1IP 3L0TA 4AYKA 5I3MA 3LK8A 5I4OA 1B8YA 1OS2A 1XUDA 2ERPA 3EDIA 5I12A 1HV5A 1H71P 1R54A 1BZSA 1HTDA 2Y6DA 2FV5A 3HYGA 3G5CA 4PKVA 1BUVM 3L0VA 4HX3A 4WKIA 1IABA 1JKYA 4L63A 1D8MA 2OY4A 2SRTA 1SU3A 2JSDA 2AIGP 1MMPA 2X7MA 1CGLA 1JANA 4I03A 3DL1A 2YIGA 4EFSA 2DW1A 4G9LA 1OO9A 4L7AA 3KWVC 1OM6A 4L6TA 2D1OA 4H3XA 3BA0A 2L0RA 3AYUA 2RJQA 5H8XA 1FBLA 1ZS0A 3OHLA 2Z2DA 3LUMA 4FU4A 2YUFA 1HFSA 3LKAA 5BPAA 3EDZA 3LMCA 1DMTA 1AF0A 1MNCA 3B2ZA 4GR0A 1G49A 4GQLA 2O3EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KUI A;  5D1T A;  2W14 A;  2OW0 A;  1SAT A;  3E8R A;  4JP4 A;  1KUF A;  3V96 B;  1BM6 A;  1G9K A;  2K2G A;  1KUG A;  1L6J A;  1CAQ A;  3LJZ A;  5CUH A;  3ZUK A;  1IAD A;  2V4B A;  3KRY A;  2WO8 A;  1SLN A;  1XFV A;  2MZH A;  1BIW A;  1ZXV A;  2W12 A;  4HMA A;  2K9C A;  3K7N A;  2D1N A;  4Q1L A;  1PWQ A;  1Y8J A;  2I47 A;  2OW2 A;  2OI0 A;  1XUC A;  3DWB A;  1Q3A A;  1KAP P;  456C A;  3HB2 P;  3KHI A;  4FXY P;  5I2Z A;  4L19 A;  2MLS A;  1XUR A;  4PKR A;  4IN9 A;  2JT5 A;  1JAP A;  3AIG A;  3LJG A;  1BKC I;  1OMJ A;  3NX7 A;  3USN A;  3LUN A;  3O2X A;  1K7G A;  4AUO A;  3KEK A;  1R1I A;  1YOU A;  2CKI A;  4GF1 A;  3I7G A;  3HBU P;  3I7I A;  1WNI A;  4A7B A;  1HFC A;  1R55 A;  1UMS A;  3F19 A;  2J83 A;  1CGF A;  3HY7 A;  4PKS A;  5JMY A;  3MA2 A;  1BSW A;  1GKC A;  1OM8 A;  1GE6 A;  4GR3 A;  4FVL A;  1ATL A;  1R1H A;  2OXW A;  3LIK A;  1CQR A;  3LIL A;  1QUA A;  1FLS A;  1G12 A;  1BQO A;  4DF9 A;  2TCL A;  3OHO A;  1EB6 A;  1C8T A;  2AYK A;  2MZE A;  3HBV P;  4R3V A;  2J0T A;  1I76 A;  1XFZ A;  4XM7 A;  2JNP A;  4H30 A;  1UEA A;  1A86 A;  3EHX A;  4WF6 A;  1D8F A;  3HDA P;  1XFY A;  1GE5 A;  1YCM A;  4JQG A;  2XS4 A;  3EDG A;  3B92 A;  1MMR A;  5I43 A;  5L7F A;  2OZR A;  3DSL A;  5BOT A;  5D3C A;  4ON1 A;  2DW2 A;  1IAC A;  4JA1 A;  3ELM A;  5B5O A;  3LIR A;  3EWJ A;  1OM7 A;  5D1S A;  2O36 A;  1KUH A;  4PKQ A;  1EUB A;  1O0T A;  3DNG A;  3F17 A;  4WK7 A;  1JK3 A;  1MMB A;  2HU6 A;  4AXQ A;  1UTZ A;  1ZVX A;  1BQQ M;  1FM1 A;  2E3X A;  1CXV A;  3LE9 A;  1AST A;  1ZTQ A;  3F1A A;  3RTS A;  3EHY A;  3AYK A;  1B3D A;  1JAO A;  1CIZ A;  3GBO A;  4JPA A;  1GKD A;  3TSK A;  2ERQ A;  3LGP A;  4GUY A;  1JAQ A;  1G05 A;  1O0Q A;  1K7I A;  1USN A;  830C A;  1ZP5 A;  1AKL A;  3TT4 A;  3WV2 A;  2E2D A;  2JIH A;  1UMT A;  3U1R A;  1GE7 A;  1K7Q A;  1HOV A;  1R1J A;  2KRJ A;  1BUD A;  1KBC A;  3F15 A;  1OS9 A;  1GO7 P;  2X3B A;  4J4M A;  2WO9 A;  4PKT A;  1XFW A;  3CKI A;  2X3A A;  4H2E A;  1I73 A;  3ZVS A;  1J7N A;  1BKC E;  4ZR5 A;  3B8Z A;  1ROS A;  2W13 A;  3Q2H A;  5D2B A;  1YQY A;  2RJP A;  2FV9 A;  3KME A;  3TS4 A;  4H1Q A;  1PWV A;  4WZV A;  5D7W A;  4GR8 A;  3KMC A;  3LQB A;  1XFX A;  1A85 A;  3TVC A;  4XM6 A;  1SRP A;  1Y93 A;  4ILW D;  2POJ A;  3WV1 A;  1IAE A;  2OVX A;  3HDB A;  1JIZ A;  3P24 A;  1DTH A;  3P1V A;  2DDF A;  5CZM A;  2DW0 A;  1Z3J A;  4H76 A;  1BKC A;  4XBH A;  3EDH A;  1YP1 A;  1IAA A;  1SMP A;  4JIJ A;  4PKU A;  1PWW A;  4PKW A;  1JH1 A;  1QIB A;  1C7K A;  5CXA A;  3LQ0 A;  5I0L A;  3G42 A;  1UTT A;  3VTG A;  4IUW A;  3N2V A;  1CK7 A;  1D5J A;  4H49 A;  4AIG A;  4FXQ A;  3DPF A;  4WKE A;  2OVZ A;  1JJ9 A;  4XM8 A;  2OW9 A;  1JIW P;  3O64 A;  2ERO A;  4A3W A;  1QIC A;  4DD8 A;  1C3I A;  2MLR A;  2W15 A;  2N8R A;  1QJI A;  5D1U A;  2PJT A;  4I35 A;  3VI1 A;  2MZI A;  3Q2G A;  1ND1 A;  2OY2 A;  1XFU A;  2QPJ A;  2XS3 A;  1Y0V A;  1ZXC A;  5B5P A;  2Y6C A;  1PWP A;  4CTH A;  1RM8 A;  4H82 A;  1PWU A;  4H84 A;  2DDY A;  966C A;  2A8H A;  3DPE A;  4QKZ A;  1AYK A;  3HY9 A;  2W0D A;  2JT6 A;  3RTT A;  3LJT A;  4GWN A;  1QIA A;  3F16 A;  1D7X A;  3F18 A;  3N2U A;  1EAK A;  5L79 A;  4DPE A;  1GXD A;  1QJJ A;  3KEJ A;  2WOA A;  5BOY A;  1SLM A;  1IAG A;  4G0D A;  1MMQ A;  1HY7 A;  3LEA A;  3WV3 A;  3KEC A;  3ZXH A;  4DV8 A;  2YB9 A;  1CGE A;  2X3C A;  1GO8 P;  4GWM A;  1KUK A;  4IJO A;  3K7L A;  2OXZ A;  4XCT A;  3SHI A;  2CLT A;  2OXU A;  1RMZ A;  5LAB A;  3UVC A;  1S4B P;  2OW1 A;  1G4K A;  2USN A;  1I1I P;  3L0T A;  4AYK A;  5I3M A;  3LK8 A;  5I4O A;  1B8Y A;  1OS2 A;  1XUD A;  2ERP A;  3EDI A;  5I12 A;  1HV5 A;  1H71 P;  1R54 A;  1BZS A;  1HTD A;  2Y6D A;  2FV5 A;  3HYG A;  3G5C A;  4PKV A;  1BUV M;  3L0V A;  4HX3 A;  4WKI A;  1IAB A;  1JKY A;  4L63 A;  1D8M A;  2OY4 A;  2SRT A;  1SU3 A;  2JSD A;  2AIG P;  1MMP A;  2X7M A;  1CGL A;  1JAN A;  4I03 A;  3DL1 A;  2YIG A;  4EFS A;  2DW1 A;  4G9L A;  1OO9 A;  3KWV C;  1OM6 A;  4L6T A;  2D1O A;  4H3X A;  3BA0 A;  2L0R A;  3AYU A;  2RJQ A;  5H8X A;  1FBL A;  1ZS0 A;  3OHL A;  2Z2D A;  3LUM A;  4FU4 A;  1HFS A;  3LKA A;  5BPA A;  3EDZ A;  3LMC A;  1DMT A;  1AF0 A;  1MNC A;  3B2Z A;  4GR0 A;  1G49 A;  4GQL A;  2O3E A; 
#chains in the Genus database with same CATH topology
 1XM5 A;  1KUI A;  5D1T A;  2W14 A;  2OW0 A;  1SAT A;  3E8R A;  4JP4 A;  1KUF A;  3V96 B;  1BM6 A;  1G9K A;  2K2G A;  1KUG A;  1L6J A;  1CAQ A;  3LJZ A;  5CUH A;  3ZUK A;  1IAD A;  2V4B A;  3KRY A;  2WO8 A;  1SLN A;  1XFV A;  2MZH A;  1BIW A;  1ZXV A;  2W12 A;  4HMA A;  2K9C A;  3K7N A;  2D1N A;  4Q1L A;  1PWQ A;  1Y8J A;  2I47 A;  2OW2 A;  2OI0 A;  1XUC A;  3DWB A;  1Q3A A;  1KAP P;  456C A;  3HB2 P;  3KHI A;  4FXY P;  5I2Z A;  4L19 A;  2MLS A;  1XUR A;  4PKR A;  1XAX A;  4IN9 A;  2JT5 A;  1JAP A;  3AIG A;  3LJG A;  1BKC I;  1OMJ A;  3NX7 A;  3USN A;  3DTI A;  3LUN A;  3O2X A;  1K7G A;  4AUO A;  3KEK A;  1R1I A;  1YOU A;  2CKI A;  4GF1 A;  3I7G A;  3HBU P;  3I7I A;  1WNI A;  4A7B A;  1HFC A;  1R55 A;  1UMS A;  3F19 A;  2J83 A;  1CGF A;  3HY7 A;  4PKS A;  5JMY A;  3MA2 A;  1BSW A;  1GKC A;  1OM8 A;  1GE6 A;  4GR3 A;  4FVL A;  1ATL A;  1R1H A;  2OXW A;  3LIK A;  1CQR A;  3LIL A;  1QUA A;  1FLS A;  1G12 A;  1BQO A;  4DF9 A;  2TCL A;  3OHO A;  1EB6 A;  1C8T A;  2AYK A;  2MZE A;  3HBV P;  4R3V A;  2J0T A;  1I76 A;  1XFZ A;  4XM7 A;  2JNP A;  4H30 A;  1UEA A;  1A86 A;  3EHX A;  4WF6 A;  1D8F A;  3HDA P;  1XFY A;  1GE5 A;  1YCM A;  4JQG A;  2XS4 A;  3EDG A;  3B92 A;  1MMR A;  5I43 A;  5L7F A;  2OZR A;  3DSL A;  5BOT A;  5D3C A;  4ON1 A;  2DW2 A;  1IAC A;  4JA1 A;  3ELM A;  5B5O A;  3LIR A;  3EWJ A;  1OM7 A;  5D1S A;  2O36 A;  1KUH A;  4PKQ A;  1EUB A;  1O0T A;  3DNG A;  3F17 A;  4WK7 A;  1JK3 A;  1MMB A;  2HU6 A;  4AXQ A;  1UTZ A;  1ZVX A;  1BQQ M;  1FM1 A;  2E3X A;  1CXV A;  3LE9 A;  1AST A;  1ZTQ A;  3F1A A;  3RTS A;  3EHY A;  3AYK A;  1B3D A;  1JAO A;  1CIZ A;  3GBO A;  4JPA A;  1GKD A;  3TSK A;  2ERQ A;  3LGP A;  4GUY A;  1JAQ A;  1G05 A;  1O0Q A;  1K7I A;  1USN A;  830C A;  1ZP5 A;  1AKL A;  3TT4 A;  3WV2 A;  2E2D A;  2JIH A;  1UMT A;  3U1R A;  1GE7 A;  1K7Q A;  1HOV A;  1R1J A;  2KRJ A;  1BUD A;  1KBC A;  3F15 A;  1OS9 A;  1GO7 P;  2X3B A;  4J4M A;  2WO9 A;  4PKT A;  1XFW A;  3CKI A;  2X3A A;  4H2E A;  1I73 A;  3ZVS A;  1J7N A;  1BKC E;  4ZR5 A;  3B8Z A;  1ROS A;  2W13 A;  3Q2H A;  5D2B A;  1YQY A;  2RJP A;  2FV9 A;  3KME A;  3TS4 A;  4H1Q A;  1PWV A;  4WZV A;  5D7W A;  4GR8 A;  3KMC A;  3LQB A;  1XFX A;  1A85 A;  3TVC A;  4XM6 A;  1SRP A;  1Y93 A;  4ILW D;  3DTK A;  2POJ A;  3WV1 A;  1IAE A;  2OVX A;  3HDB A;  1JIZ A;  3P24 A;  1DTH A;  3P1V A;  2DDF A;  5CZM A;  2DW0 A;  1Z3J A;  4H76 A;  1BKC A;  4XBH A;  3EDH A;  1YP1 A;  1IAA A;  1SMP A;  4JIJ A;  4PKU A;  1PWW A;  4PKW A;  1JH1 A;  1QIB A;  1C7K A;  5CXA A;  3LQ0 A;  5I0L A;  3G42 A;  1UTT A;  3VTG A;  4IUW A;  3N2V A;  1CK7 A;  1D5J A;  4H49 A;  4AIG A;  4FXQ A;  3DPF A;  4WKE A;  2OVZ A;  1JJ9 A;  4XM8 A;  2OW9 A;  1JIW P;  3O64 A;  2ERO A;  4A3W A;  1QIC A;  4DD8 A;  1C3I A;  2MLR A;  1OZ9 A;  2W15 A;  2N8R A;  1QJI A;  5D1U A;  2PJT A;  4I35 A;  3VI1 A;  2MZI A;  3Q2G A;  1ND1 A;  2OY2 A;  1XFU A;  2QPJ A;  2XS3 A;  1Y0V A;  1ZXC A;  5B5P A;  2Y6C A;  1PWP A;  4CTH A;  1RM8 A;  4H82 A;  1PWU A;  4H84 A;  2DDY A;  966C A;  2A8H A;  3DPE A;  4QKZ A;  1AYK A;  3HY9 A;  2W0D A;  2JT6 A;  3RTT A;  3LJT A;  4GWN A;  1TVI A;  1QIA A;  3F16 A;  1D7X A;  3F18 A;  3N2U A;  1EAK A;  5L79 A;  4DPE A;  1GXD A;  1QJJ A;  3KEJ A;  2WOA A;  5BOY A;  3DTE A;  1SLM A;  1IAG A;  4G0D A;  1MMQ A;  1HY7 A;  3LEA A;  3WV3 A;  3KEC A;  3ZXH A;  4DV8 A;  2YB9 A;  1CGE A;  2X3C A;  1GO8 P;  4GWM A;  1KUK A;  4IJO A;  3K7L A;  2OXZ A;  4XCT A;  3SHI A;  2CLT A;  2OXU A;  1RMZ A;  5LAB A;  3UVC A;  1S4B P;  2OW1 A;  1G4K A;  2USN A;  1I1I P;  3L0T A;  4AYK A;  5I3M A;  3LK8 A;  5I4O A;  1B8Y A;  1OS2 A;  1XUD A;  2ERP A;  3EDI A;  5I12 A;  1HV5 A;  1H71 P;  1R54 A;  1BZS A;  1HTD A;  2Y6D A;  2FV5 A;  3HYG A;  3G5C A;  4PKV A;  1BUV M;  3L0V A;  4HX3 A;  4WKI A;  1IAB A;  1JKY A;  4L63 A;  1D8M A;  2OY4 A;  2SRT A;  1SU3 A;  2JSD A;  2AIG P;  1MMP A;  2X7M A;  1CGL A;  1JAN A;  4I03 A;  3DL1 A;  2YIG A;  4EFS A;  2DW1 A;  4G9L A;  1OO9 A;  4L7A A;  3KWV C;  1OM6 A;  4L6T A;  2D1O A;  4H3X A;  3BA0 A;  2L0R A;  3AYU A;  2RJQ A;  5H8X A;  1FBL A;  1ZS0 A;  3OHL A;  2Z2D A;  3LUM A;  4FU4 A;  2YUF A;  1HFS A;  3LKA A;  5BPA A;  3EDZ A;  3LMC A;  1DMT A;  1AF0 A;  1MNC A;  3B2Z A;  4GR0 A;  1G49 A;  4GQL A;  2O3E A; 
#chains in the Genus database with same CATH homology
 1KUI A;  5D1T A;  2W14 A;  2OW0 A;  1SAT A;  3E8R A;  4JP4 A;  1KUF A;  3V96 B;  1BM6 A;  1G9K A;  2K2G A;  1KUG A;  1L6J A;  1CAQ A;  3LJZ A;  5CUH A;  3ZUK A;  1IAD A;  2V4B A;  3KRY A;  2WO8 A;  1SLN A;  1XFV A;  2MZH A;  1BIW A;  1ZXV A;  2W12 A;  4HMA A;  2K9C A;  3K7N A;  2D1N A;  4Q1L A;  1PWQ A;  1Y8J A;  2I47 A;  2OW2 A;  2OI0 A;  1XUC A;  3DWB A;  1Q3A A;  1KAP P;  456C A;  3HB2 P;  3KHI A;  4FXY P;  5I2Z A;  4L19 A;  2MLS A;  1XUR A;  4PKR A;  4IN9 A;  2JT5 A;  1JAP A;  3AIG A;  3LJG A;  1BKC I;  1OMJ A;  3NX7 A;  3USN A;  3DTI A;  3LUN A;  3O2X A;  1K7G A;  4AUO A;  3KEK A;  1R1I A;  1YOU A;  2CKI A;  4GF1 A;  3I7G A;  3HBU P;  3I7I A;  1WNI A;  4A7B A;  1HFC A;  1R55 A;  1UMS A;  3F19 A;  2J83 A;  1CGF A;  3HY7 A;  4PKS A;  5JMY A;  3MA2 A;  1BSW A;  1GKC A;  1OM8 A;  1GE6 A;  4GR3 A;  4FVL A;  1ATL A;  1R1H A;  2OXW A;  3LIK A;  1CQR A;  3LIL A;  1QUA A;  1FLS A;  1G12 A;  1BQO A;  4DF9 A;  2TCL A;  3OHO A;  1EB6 A;  1C8T A;  2AYK A;  2MZE A;  3HBV P;  4R3V A;  2J0T A;  1I76 A;  1XFZ A;  4XM7 A;  2JNP A;  4H30 A;  1UEA A;  1A86 A;  3EHX A;  4WF6 A;  1D8F A;  3HDA P;  1XFY A;  1GE5 A;  1YCM A;  4JQG A;  2XS4 A;  3EDG A;  3B92 A;  1MMR A;  5I43 A;  5L7F A;  2OZR A;  3DSL A;  5BOT A;  5D3C A;  4ON1 A;  2DW2 A;  1IAC A;  4JA1 A;  3ELM A;  5B5O A;  3LIR A;  3EWJ A;  1OM7 A;  5D1S A;  2O36 A;  1KUH A;  4PKQ A;  1EUB A;  1O0T A;  3DNG A;  3F17 A;  4WK7 A;  1JK3 A;  1MMB A;  2HU6 A;  4AXQ A;  1UTZ A;  1ZVX A;  1BQQ M;  1FM1 A;  2E3X A;  1CXV A;  3LE9 A;  1AST A;  1ZTQ A;  3F1A A;  3RTS A;  3EHY A;  3AYK A;  1B3D A;  1JAO A;  1CIZ A;  3GBO A;  4JPA A;  1GKD A;  3TSK A;  2ERQ A;  3LGP A;  4GUY A;  1JAQ A;  1G05 A;  1O0Q A;  1K7I A;  1USN A;  830C A;  1ZP5 A;  1AKL A;  3TT4 A;  3WV2 A;  2E2D A;  2JIH A;  1UMT A;  3U1R A;  1GE7 A;  1K7Q A;  1HOV A;  1R1J A;  2KRJ A;  1BUD A;  1KBC A;  3F15 A;  1OS9 A;  1GO7 P;  2X3B A;  4J4M A;  2WO9 A;  4PKT A;  1XFW A;  3CKI A;  2X3A A;  4H2E A;  1I73 A;  3ZVS A;  1J7N A;  1BKC E;  4ZR5 A;  3B8Z A;  1ROS A;  2W13 A;  3Q2H A;  5D2B A;  1YQY A;  2RJP A;  2FV9 A;  3KME A;  3TS4 A;  4H1Q A;  1PWV A;  4WZV A;  5D7W A;  4GR8 A;  3KMC A;  3LQB A;  1XFX A;  1A85 A;  3TVC A;  4XM6 A;  1SRP A;  1Y93 A;  4ILW D;  3DTK A;  2POJ A;  3WV1 A;  1IAE A;  2OVX A;  3HDB A;  1JIZ A;  3P24 A;  1DTH A;  3P1V A;  2DDF A;  5CZM A;  2DW0 A;  1Z3J A;  4H76 A;  1BKC A;  4XBH A;  3EDH A;  1YP1 A;  1IAA A;  1SMP A;  4JIJ A;  4PKU A;  1PWW A;  4PKW A;  1JH1 A;  1QIB A;  1C7K A;  5CXA A;  3LQ0 A;  5I0L A;  3G42 A;  1UTT A;  3VTG A;  4IUW A;  3N2V A;  1CK7 A;  1D5J A;  4H49 A;  4AIG A;  4FXQ A;  3DPF A;  4WKE A;  2OVZ A;  1JJ9 A;  4XM8 A;  2OW9 A;  1JIW P;  3O64 A;  2ERO A;  4A3W A;  1QIC A;  4DD8 A;  1C3I A;  2MLR A;  2W15 A;  2N8R A;  1QJI A;  5D1U A;  2PJT A;  4I35 A;  3VI1 A;  2MZI A;  3Q2G A;  1ND1 A;  2OY2 A;  1XFU A;  2QPJ A;  2XS3 A;  1Y0V A;  1ZXC A;  5B5P A;  2Y6C A;  1PWP A;  4CTH A;  1RM8 A;  4H82 A;  1PWU A;  4H84 A;  2DDY A;  966C A;  2A8H A;  3DPE A;  4QKZ A;  1AYK A;  3HY9 A;  2W0D A;  2JT6 A;  3RTT A;  3LJT A;  4GWN A;  1QIA A;  3F16 A;  1D7X A;  3F18 A;  3N2U A;  1EAK A;  5L79 A;  4DPE A;  1GXD A;  1QJJ A;  3KEJ A;  2WOA A;  5BOY A;  3DTE A;  1SLM A;  1IAG A;  4G0D A;  1MMQ A;  1HY7 A;  3LEA A;  3WV3 A;  3KEC A;  3ZXH A;  4DV8 A;  2YB9 A;  1CGE A;  2X3C A;  1GO8 P;  4GWM A;  1KUK A;  4IJO A;  3K7L A;  2OXZ A;  4XCT A;  3SHI A;  2CLT A;  2OXU A;  1RMZ A;  5LAB A;  3UVC A;  1S4B P;  2OW1 A;  1G4K A;  2USN A;  1I1I P;  3L0T A;  4AYK A;  5I3M A;  3LK8 A;  5I4O A;  1B8Y A;  1OS2 A;  1XUD A;  2ERP A;  3EDI A;  5I12 A;  1HV5 A;  1H71 P;  1R54 A;  1BZS A;  1HTD A;  2Y6D A;  2FV5 A;  3HYG A;  3G5C A;  4PKV A;  1BUV M;  3L0V A;  4HX3 A;  4WKI A;  1IAB A;  1JKY A;  4L63 A;  1D8M A;  2OY4 A;  2SRT A;  1SU3 A;  2JSD A;  2AIG P;  1MMP A;  2X7M A;  1CGL A;  1JAN A;  4I03 A;  3DL1 A;  2YIG A;  4EFS A;  2DW1 A;  4G9L A;  1OO9 A;  4L7A A;  3KWV C;  1OM6 A;  4L6T A;  2D1O A;  4H3X A;  3BA0 A;  2L0R A;  3AYU A;  2RJQ A;  5H8X A;  1FBL A;  1ZS0 A;  3OHL A;  2Z2D A;  3LUM A;  4FU4 A;  2YUF A;  1HFS A;  3LKA A;  5BPA A;  3EDZ A;  3LMC A;  1DMT A;  1AF0 A;  1MNC A;  3B2Z A;  4GR0 A;  1G49 A;  4GQL A;  2O3E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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