3F16A

Crystal structure of the catalytic domain of human mmp12 complexed with the inhibitor (r)-n-(3-hydroxy-1-nitroso-1-oxopropan-2-yl)-4-methoxybenzenesulfonamide
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
158
structure length
158
Chain Sequence
GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Exploring the subtleties of drug-receptor interactions: the case of matrix metalloproteinases.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Macrophage metalloelastase
total genus 43
structure length 158
sequence length 158
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2008-10-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3f16A00
2Y6CA 4FXQA 4PKVA 3LIRA 1QJJA 1IAEA 4PKWA 2USNA 4XBHA 4DD8A 3EDZA 4GF1A 4G9LA 3CKIA 3KWVC 1L6JA 3DNGA 3EHYA 3AIGA 2OXZA 1GXDA 5BOYA 1PWWA 1CK7A 1WNIA 3LJTA 3I7IA 4WKEA 4H82A 2D1OA 1QUAA 2TCLA 5B5OA 5I2ZA 1MMPA 1R1IA 3LQ0A 2OW0A 2MLSA 1KUIA 4IUWA 2CKIA 1OM8A 2I47A 1ZXVA 1JIWP 2MZHA 3Q2HA 5CXAA 2CLTA 3HY9A 4AUOA 1SRPA 2N8RA 1ND1A 2X7MA 2MLRA 2W0DA 1CGEA 1DMTA 1G12A 3DPFA 1G9KA 1BUDA 1R1JA 3TSKA 4PKSA 1BM6A 1I76A 4GWMA 3ZXHA 2RJQA 1JANA 1G4KA 1ZTQA 2A8HA 4H2EA 4H49A 4FU4A 3AYUA 3USNA 3SHIA 1XUDA 1G49A 3LMCA 2EROA 3KEKA 1CXVA 3RTSA 1JK3A 1Y93A 2W13A 1GO7P 2WO8A 3LQBA 5I4OA 1YCMA 3F15A 1AKLA 4A7BA 1SATA 2OW1A 2DW2A 1Y0VA 1OS2A 1BQQM 5D2BA 1KUFA 3KMCA 3LJGA 3N2UA 1EUBA 3DL1A 4JPAA 2JT6A 1MMBA 3LE9A 4HMAA 1ZVXA 4L63A 1CIZA 1IAAA 3GBOA 5I0LA 3E8RA 4QKZA 4GR0A 3LUNA 3L0VA 3UVCA 4I35A 1BSWA 4I03A 1GKDA 1YP1A 1HFSA 1Z3JA 2J83A 1OO9A 1PWVA 2JIHA 1CGLA 1CQRA 1QIAA 3LGPA 4XCTA 2V4BA 1Q3AA 5BOTA 3O64A 1ZS0A 2PJTA 1A86A 4IN9A 3F1AA 1FLSA 1HY7A 1UMSA 1ATLA 3VTGA 2W14A 1CAQA 3O2XA 3ZVSA 2O36A 1D8MA 2X3BA 1KAPP 1UMTA 1UTTA 1XFWA 1KUKA 1HFCA 3OHLA 966CA 2OW9A 2OXUA 1ZXCA 4H3XA 3OHOA 4IJOA 5D1TA 5D3CA 1I1IP 1BKCA 1D8FA 1O0TA 2DDFA 5BPAA 2POJA 3KMEA 3LILA 3N2VA 1JJ9A 1CGFA 2J0TA 456CA 1XFZA 1HOVA 1JAOA 4G0DA 2DDYA 4PKTA 1C7KA 1KUHA 5D1UA 3WV2A 5I43A 2FV5A 2E2DA 4XM6A 3TS4A 2X3CA 5B5PA 2WO9A 5LABA 4AYKA 4J4MA 2OW2A 4DF9A 3G42A 1XURA 3WV1A 3P1VA 3L0TA 4DPEA 2OXWA 2DW1A 2OVXA 1KUGA 3HDAP 4ILWD 1K7IA 3KHIA 4A3WA 3LJZA 1OS9A 4L19A 1QIBA 2JSDA 1D5JA 3ELMA 2KRJA 1XFUA 3EDGA 1R54A 2K2GA 1HTDA 1GE6A 3TVCA 2RJPA 4L6TA 1QJIA 5JMYA 1QICA 1SMPA 3MA2A 3B2ZA 1R1HA 1JH1A 1ZP5A 4GR3A 1JIZA 1MMRA 1RM8A 3HB2P 4XM7A 3LIKA 1J7NA 1BKCE 3AYKA 2MZIA 1I73A 1R55A 1KBCA 3TT4A 5I12A 2JT5A 1H71P 4PKUA 4H1QA 5CUHA 4WF6A 1OMJA 3ZUKA 3EHXA 3HY7A 1YOUA 3K7LA 1XFXA 1K7GA 1IADA 2AYKA 830CA 2YB9A 4AIGA 1JAQA 2SRTA 3KRYA 2ERPA 1USNA 4WZVA 1G05A 4PKRA 1EB6A 1XFYA 1GKCA 1UEAA 1A85A 5D7WA 1HV5A 3F18A 4WK7A 3HBVP 3G5CA 2L0RA 3K7NA 2X3AA 1PWQA 1GE5A 1ASTA 3DPEA 4FVLA 1SU3A 3LKAA 1AF0A 5L79A 3KECA 1IAGA 1FBLA 2OI0A 2ERQA 2OY4A 4ON1A 5L7FA 1SLNA 2K9CA 3F19A 4FXYP 1EAKA 1BUVM 3B8ZA 1MMQA 1SLMA 3Q2GA 1BZSA 1Y8JA 3KEJA 1OM6A 2OY2A 4EFSA 2XS3A 2QPJA 4GR8A 1C8TA 2XS4A 3F17A 3LEAA 2WOAA 3P24A 1XUCA 3HDBA 3F16A 3V96B 2MZEA 2OVZA 2YIGA 2AIGP 1DTHA 4JQGA 3EDHA 4XM8A 1UTZA 4WKIA 2DW0A 4CTHA 4AXQA 2FV9A 3NX7A 4H30A 3RTTA 4JIJA 1K7QA 1B3DA 5CZMA 1BQOA 4GWNA 2HU6A 5I3MA 2W12A 1GE7A 1RMZA 2Y6DA 1JKYA 4PKQA 1MNCA 3BA0A 2JNPA 4H76A 2OZRA 1C3IA 1O0QA 4R3VA 4GUYA 2D1NA 3B92A 4DV8A 1IACA 1FM1A 1OM7A 1YQYA 3LK8A 4JA1A 1S4BP 2Z2DA 3DWBA 3EWJA 1XFVA 1JAPA 3WV3A 1BIWA 1B8YA 1PWPA 2E3XA 3VI1A 1ROSA 4HX3A 1IABA 3LUMA 1D7XA 3U1RA 3HYGA 3EDIA 4GQLA 5D1SA 1GO8P 1PWUA 5H8XA 3I7GA 4JP4A 4ZR5A 1AYKA 4H84A 2O3EA 1BKCI 3HBUP 3DSLA 4Q1LA 2W15A
chains in the Genus database with same CATH superfamily
2Y6CA 4FXQA 4PKVA 3LIRA 1QJJA 1IAEA 4PKWA 2USNA 4XBHA 4DD8A 3EDZA 4GF1A 4G9LA 3CKIA 3KWVC 1L6JA 3DNGA 3EHYA 3AIGA 2OXZA 1GXDA 5BOYA 1PWWA 1CK7A 1WNIA 3LJTA 3I7IA 4WKEA 4H82A 2D1OA 1QUAA 2TCLA 5B5OA 5I2ZA 1MMPA 1R1IA 3LQ0A 2OW0A 2MLSA 1KUIA 4IUWA 2CKIA 1OM8A 2I47A 1ZXVA 1JIWP 2MZHA 3Q2HA 5CXAA 2CLTA 3HY9A 4AUOA 1SRPA 2N8RA 1ND1A 2X7MA 2MLRA 2W0DA 1CGEA 1XM5A 1DMTA 1G12A 3DPFA 1G9KA 1BUDA 1R1JA 3TSKA 4PKSA 1BM6A 1I76A 4GWMA 3ZXHA 2RJQA 1JANA 1G4KA 1ZTQA 2A8HA 4H2EA 4H49A 4FU4A 3AYUA 3USNA 3SHIA 1XUDA 1G49A 3LMCA 2EROA 3KEKA 1CXVA 3RTSA 1JK3A 1Y93A 2W13A 1GO7P 2WO8A 3LQBA 5I4OA 1YCMA 3F15A 1AKLA 4A7BA 1SATA 2OW1A 2DW2A 1Y0VA 1OS2A 1BQQM 5D2BA 1KUFA 3KMCA 3LJGA 3N2UA 1EUBA 3DL1A 4JPAA 2JT6A 1MMBA 3LE9A 4HMAA 1ZVXA 4L63A 1CIZA 1IAAA 3GBOA 5I0LA 3E8RA 4QKZA 4GR0A 3LUNA 4L7AA 3L0VA 3UVCA 4I35A 1BSWA 4I03A 1GKDA 1YP1A 1HFSA 1Z3JA 2J83A 1OO9A 1PWVA 2JIHA 1CGLA 1CQRA 1QIAA 3LGPA 4XCTA 2V4BA 1Q3AA 5BOTA 3O64A 1ZS0A 2PJTA 1A86A 4IN9A 3F1AA 1FLSA 1TVIA 1HY7A 1UMSA 1ATLA 3VTGA 2W14A 1CAQA 3O2XA 3ZVSA 2O36A 1D8MA 2X3BA 1KAPP 1UMTA 1UTTA 1XFWA 1KUKA 1HFCA 3OHLA 966CA 2OW9A 2OXUA 1ZXCA 4H3XA 3OHOA 4IJOA 5D1TA 5D3CA 1I1IP 1BKCA 1D8FA 1O0TA 2DDFA 5BPAA 2POJA 3KMEA 3LILA 3N2VA 1JJ9A 1CGFA 2J0TA 456CA 1XFZA 1HOVA 1JAOA 4G0DA 2DDYA 4PKTA 1C7KA 1KUHA 5D1UA 3WV2A 5I43A 2FV5A 2E2DA 4XM6A 3TS4A 2X3CA 5B5PA 2WO9A 5LABA 4AYKA 4J4MA 2OW2A 4DF9A 3G42A 1XURA 3WV1A 3P1VA 3L0TA 4DPEA 2OXWA 2DW1A 2OVXA 1KUGA 3HDAP 4ILWD 1K7IA 3KHIA 4A3WA 3LJZA 1OS9A 4L19A 1QIBA 2JSDA 1D5JA 3ELMA 2KRJA 1XFUA 3EDGA 1R54A 2K2GA 1HTDA 1GE6A 3TVCA 2RJPA 4L6TA 1QJIA 5JMYA 1QICA 1SMPA 3MA2A 3B2ZA 1R1HA 1JH1A 1ZP5A 4GR3A 1JIZA 1MMRA 1RM8A 3HB2P 4XM7A 3LIKA 1J7NA 1BKCE 3AYKA 2MZIA 1I73A 1R55A 1KBCA 3TT4A 5I12A 2JT5A 1H71P 4PKUA 3DTIA 4H1QA 5CUHA 4WF6A 1OMJA 3ZUKA 1XAXA 3EHXA 3HY7A 1YOUA 3K7LA 1XFXA 1K7GA 1IADA 2AYKA 830CA 2YB9A 4AIGA 1JAQA 2SRTA 3KRYA 2ERPA 1USNA 4WZVA 1G05A 4PKRA 1EB6A 1XFYA 1GKCA 1UEAA 1A85A 3DTKA 2YUFA 5D7WA 1HV5A 3F18A 4WK7A 3HBVP 3G5CA 2L0RA 3K7NA 2X3AA 1PWQA 1GE5A 1ASTA 3DPEA 4FVLA 1SU3A 3LKAA 1AF0A 5L79A 3KECA 1IAGA 1FBLA 2OI0A 2ERQA 2OY4A 4ON1A 5L7FA 1SLNA 2K9CA 3F19A 4FXYP 1EAKA 1BUVM 3B8ZA 1MMQA 1SLMA 3Q2GA 1BZSA 1Y8JA 3KEJA 1OM6A 2OY2A 4EFSA 2XS3A 2QPJA 4GR8A 1C8TA 2XS4A 3F17A 3LEAA 2WOAA 3P24A 1XUCA 3HDBA 3F16A 3V96B 2MZEA 2OVZA 2YIGA 2AIGP 1DTHA 4JQGA 1OZ9A 3EDHA 4XM8A 1UTZA 4WKIA 2DW0A 4CTHA 4AXQA 2FV9A 3NX7A 4H30A 3RTTA 4JIJA 1K7QA 1B3DA 5CZMA 1BQOA 4GWNA 2HU6A 5I3MA 2W12A 1GE7A 1RMZA 2Y6DA 1JKYA 4PKQA 1MNCA 3BA0A 2JNPA 4H76A 2OZRA 1C3IA 1O0QA 4R3VA 4GUYA 2D1NA 3B92A 4DV8A 1IACA 1FM1A 1OM7A 1YQYA 3LK8A 4JA1A 1S4BP 2Z2DA 3DWBA 3EWJA 1XFVA 1JAPA 3WV3A 1BIWA 1B8YA 1PWPA 2E3XA 3VI1A 1ROSA 4HX3A 1IABA 3LUMA 1D7XA 3U1RA 3HYGA 3EDIA 4GQLA 5D1SA 1GO8P 1PWUA 3DTEA 5H8XA 3I7GA 4JP4A 4ZR5A 1AYKA 4H84A 2O3EA 1BKCI 3HBUP 3DSLA 4Q1LA 2W15A
chains in the Genus database with same CATH topology
2Y6CA 4FXQA 4PKVA 3LIRA 1QJJA 1IAEA 4PKWA 2USNA 4XBHA 4DD8A 3EDZA 4GF1A 4G9LA 3CKIA 3KWVC 1L6JA 3DNGA 3EHYA 3AIGA 2OXZA 1GXDA 5BOYA 1PWWA 1CK7A 1WNIA 3LJTA 3I7IA 4WKEA 4H82A 2D1OA 1QUAA 2TCLA 5B5OA 5I2ZA 1MMPA 1R1IA 3LQ0A 2OW0A 2MLSA 1KUIA 4IUWA 2CKIA 1OM8A 2I47A 1ZXVA 1JIWP 2MZHA 3Q2HA 5CXAA 2CLTA 3HY9A 4AUOA 1SRPA 2N8RA 1ND1A 2X7MA 2MLRA 2W0DA 1CGEA 1DMTA 1G12A 3DPFA 1G9KA 1BUDA 1R1JA 3TSKA 4PKSA 1BM6A 1I76A 4GWMA 3ZXHA 2RJQA 1JANA 1G4KA 1ZTQA 2A8HA 4H2EA 4H49A 4FU4A 3AYUA 3USNA 3SHIA 1XUDA 1G49A 3LMCA 2EROA 3KEKA 1CXVA 3RTSA 1JK3A 1Y93A 2W13A 1GO7P 2WO8A 3LQBA 5I4OA 1YCMA 3F15A 1AKLA 4A7BA 1SATA 2OW1A 2DW2A 1Y0VA 1OS2A 1BQQM 5D2BA 1KUFA 3KMCA 3LJGA 3N2UA 1EUBA 3DL1A 4JPAA 2JT6A 1MMBA 3LE9A 4HMAA 1ZVXA 4L63A 1CIZA 1IAAA 3GBOA 5I0LA 3E8RA 4QKZA 4GR0A 3LUNA 4L7AA 3L0VA 3UVCA 4I35A 1BSWA 4I03A 1GKDA 1YP1A 1HFSA 1Z3JA 2J83A 1OO9A 1PWVA 2JIHA 1CGLA 1CQRA 1QIAA 3LGPA 4XCTA 2V4BA 1Q3AA 5BOTA 3O64A 1ZS0A 2PJTA 1A86A 4IN9A 3F1AA 1FLSA 1HY7A 1UMSA 1ATLA 3VTGA 2W14A 1CAQA 3O2XA 3ZVSA 2O36A 1D8MA 2X3BA 1KAPP 1UMTA 1UTTA 1XFWA 1KUKA 1HFCA 3OHLA 966CA 2OW9A 2OXUA 1ZXCA 4H3XA 3OHOA 4IJOA 5D1TA 5D3CA 1I1IP 1BKCA 1D8FA 1O0TA 2DDFA 5BPAA 2POJA 3KMEA 3LILA 3N2VA 1JJ9A 1CGFA 2J0TA 456CA 1XFZA 1HOVA 1JAOA 4G0DA 2DDYA 4PKTA 1C7KA 1KUHA 5D1UA 3WV2A 5I43A 2FV5A 2E2DA 4XM6A 3TS4A 2X3CA 5B5PA 2WO9A 5LABA 4AYKA 4J4MA 2OW2A 4DF9A 3G42A 1XURA 3WV1A 3P1VA 3L0TA 4DPEA 2OXWA 2DW1A 2OVXA 1KUGA 3HDAP 4ILWD 1K7IA 3KHIA 4A3WA 3LJZA 1OS9A 4L19A 1QIBA 2JSDA 1D5JA 3ELMA 2KRJA 1XFUA 3EDGA 1R54A 2K2GA 1HTDA 1GE6A 3TVCA 2RJPA 4L6TA 1QJIA 5JMYA 1QICA 1SMPA 3MA2A 3B2ZA 1R1HA 1JH1A 1ZP5A 4GR3A 1JIZA 1MMRA 1RM8A 3HB2P 4XM7A 3LIKA 1J7NA 1BKCE 3AYKA 2MZIA 1I73A 1R55A 1KBCA 3TT4A 5I12A 2JT5A 1H71P 4PKUA 3DTIA 4H1QA 5CUHA 4WF6A 1OMJA 3ZUKA 3EHXA 3HY7A 1YOUA 3K7LA 1XFXA 1K7GA 1IADA 2AYKA 830CA 2YB9A 4AIGA 1JAQA 2SRTA 3KRYA 2ERPA 1USNA 4WZVA 1G05A 4PKRA 1EB6A 1XFYA 1GKCA 1UEAA 1A85A 3DTKA 2YUFA 5D7WA 1HV5A 3F18A 4WK7A 3HBVP 3G5CA 2L0RA 3K7NA 2X3AA 1PWQA 1GE5A 1ASTA 3DPEA 4FVLA 1SU3A 3LKAA 1AF0A 5L79A 3KECA 1IAGA 1FBLA 2OI0A 2ERQA 2OY4A 4ON1A 5L7FA 1SLNA 2K9CA 3F19A 4FXYP 1EAKA 1BUVM 3B8ZA 1MMQA 1SLMA 3Q2GA 1BZSA 1Y8JA 3KEJA 1OM6A 2OY2A 4EFSA 2XS3A 2QPJA 4GR8A 1C8TA 2XS4A 3F17A 3LEAA 2WOAA 3P24A 1XUCA 3HDBA 3F16A 3V96B 2MZEA 2OVZA 2YIGA 2AIGP 1DTHA 4JQGA 3EDHA 4XM8A 1UTZA 4WKIA 2DW0A 4CTHA 4AXQA 2FV9A 3NX7A 4H30A 3RTTA 4JIJA 1K7QA 1B3DA 5CZMA 1BQOA 4GWNA 2HU6A 5I3MA 2W12A 1GE7A 1RMZA 2Y6DA 1JKYA 4PKQA 1MNCA 3BA0A 2JNPA 4H76A 2OZRA 1C3IA 1O0QA 4R3VA 4GUYA 2D1NA 3B92A 4DV8A 1IACA 1FM1A 1OM7A 1YQYA 3LK8A 4JA1A 1S4BP 2Z2DA 3DWBA 3EWJA 1XFVA 1JAPA 3WV3A 1BIWA 1B8YA 1PWPA 2E3XA 3VI1A 1ROSA 4HX3A 1IABA 3LUMA 1D7XA 3U1RA 3HYGA 3EDIA 4GQLA 5D1SA 1GO8P 1PWUA 3DTEA 5H8XA 3I7GA 4JP4A 4ZR5A 1AYKA 4H84A 2O3EA 1BKCI 3HBUP 3DSLA 4Q1LA 2W15A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Y6C A;  4FXQ A;  4PKV A;  3LIR A;  1QJJ A;  1IAE A;  4PKW A;  2USN A;  4XBH A;  4DD8 A;  3EDZ A;  4GF1 A;  4G9L A;  3CKI A;  3KWV C;  1L6J A;  3DNG A;  3EHY A;  3AIG A;  2OXZ A;  1GXD A;  5BOY A;  1PWW A;  1CK7 A;  1WNI A;  3LJT A;  3I7I A;  4WKE A;  4H82 A;  2D1O A;  1QUA A;  2TCL A;  5B5O A;  5I2Z A;  1MMP A;  1R1I A;  3LQ0 A;  2OW0 A;  2MLS A;  1KUI A;  4IUW A;  2CKI A;  1OM8 A;  2I47 A;  1ZXV A;  1JIW P;  2MZH A;  3Q2H A;  5CXA A;  2CLT A;  3HY9 A;  4AUO A;  1SRP A;  2N8R A;  1ND1 A;  2X7M A;  2MLR A;  2W0D A;  1CGE A;  1DMT A;  1G12 A;  3DPF A;  1G9K A;  1BUD A;  1R1J A;  3TSK A;  4PKS A;  1BM6 A;  1I76 A;  4GWM A;  3ZXH A;  2RJQ A;  1JAN A;  1G4K A;  1ZTQ A;  2A8H A;  4H2E A;  4H49 A;  4FU4 A;  3AYU A;  3USN A;  3SHI A;  1XUD A;  1G49 A;  3LMC A;  2ERO A;  3KEK A;  1CXV A;  3RTS A;  1JK3 A;  1Y93 A;  2W13 A;  1GO7 P;  2WO8 A;  3LQB A;  5I4O A;  1YCM A;  3F15 A;  1AKL A;  4A7B A;  1SAT A;  2OW1 A;  2DW2 A;  1Y0V A;  1OS2 A;  1BQQ M;  5D2B A;  1KUF A;  3KMC A;  3LJG A;  3N2U A;  1EUB A;  3DL1 A;  4JPA A;  2JT6 A;  1MMB A;  3LE9 A;  4HMA A;  1ZVX A;  4L63 A;  1CIZ A;  1IAA A;  3GBO A;  5I0L A;  3E8R A;  4QKZ A;  4GR0 A;  3LUN A;  3L0V A;  3UVC A;  4I35 A;  1BSW A;  4I03 A;  1GKD A;  1YP1 A;  1HFS A;  1Z3J A;  2J83 A;  1OO9 A;  1PWV A;  2JIH A;  1CGL A;  1CQR A;  1QIA A;  3LGP A;  4XCT A;  2V4B A;  1Q3A A;  5BOT A;  3O64 A;  1ZS0 A;  2PJT A;  1A86 A;  4IN9 A;  3F1A A;  1FLS A;  1HY7 A;  1UMS A;  1ATL A;  3VTG A;  2W14 A;  1CAQ A;  3O2X A;  3ZVS A;  2O36 A;  1D8M A;  2X3B A;  1KAP P;  1UMT A;  1UTT A;  1XFW A;  1KUK A;  1HFC A;  3OHL A;  966C A;  2OW9 A;  2OXU A;  1ZXC A;  4H3X A;  3OHO A;  4IJO A;  5D1T A;  5D3C A;  1I1I P;  1BKC A;  1D8F A;  1O0T A;  2DDF A;  5BPA A;  2POJ A;  3KME A;  3LIL A;  3N2V A;  1JJ9 A;  1CGF A;  2J0T A;  456C A;  1XFZ A;  1HOV A;  1JAO A;  4G0D A;  2DDY A;  4PKT A;  1C7K A;  1KUH A;  5D1U A;  3WV2 A;  5I43 A;  2FV5 A;  2E2D A;  4XM6 A;  3TS4 A;  2X3C A;  5B5P A;  2WO9 A;  5LAB A;  4AYK A;  4J4M A;  2OW2 A;  4DF9 A;  3G42 A;  1XUR A;  3WV1 A;  3P1V A;  3L0T A;  4DPE A;  2OXW A;  2DW1 A;  2OVX A;  1KUG A;  3HDA P;  4ILW D;  1K7I A;  3KHI A;  4A3W A;  3LJZ A;  1OS9 A;  4L19 A;  1QIB A;  2JSD A;  1D5J A;  3ELM A;  2KRJ A;  1XFU A;  3EDG A;  1R54 A;  2K2G A;  1HTD A;  1GE6 A;  3TVC A;  2RJP A;  4L6T A;  1QJI A;  5JMY A;  1QIC A;  1SMP A;  3MA2 A;  3B2Z A;  1R1H A;  1JH1 A;  1ZP5 A;  4GR3 A;  1JIZ A;  1MMR A;  1RM8 A;  3HB2 P;  4XM7 A;  3LIK A;  1J7N A;  1BKC E;  3AYK A;  2MZI A;  1I73 A;  1R55 A;  1KBC A;  3TT4 A;  5I12 A;  2JT5 A;  1H71 P;  4PKU A;  4H1Q A;  5CUH A;  4WF6 A;  1OMJ A;  3ZUK A;  3EHX A;  3HY7 A;  1YOU A;  3K7L A;  1XFX A;  1K7G A;  1IAD A;  2AYK A;  830C A;  2YB9 A;  4AIG A;  1JAQ A;  2SRT A;  3KRY A;  2ERP A;  1USN A;  4WZV A;  1G05 A;  4PKR A;  1EB6 A;  1XFY A;  1GKC A;  1UEA A;  1A85 A;  5D7W A;  1HV5 A;  3F18 A;  4WK7 A;  3HBV P;  3G5C A;  2L0R A;  3K7N A;  2X3A A;  1PWQ A;  1GE5 A;  1AST A;  3DPE A;  4FVL A;  1SU3 A;  3LKA A;  1AF0 A;  5L79 A;  3KEC A;  1IAG A;  1FBL A;  2OI0 A;  2ERQ A;  2OY4 A;  4ON1 A;  5L7F A;  1SLN A;  2K9C A;  3F19 A;  4FXY P;  1EAK A;  1BUV M;  3B8Z A;  1MMQ A;  1SLM A;  3Q2G A;  1BZS A;  1Y8J A;  3KEJ A;  1OM6 A;  2OY2 A;  4EFS A;  2XS3 A;  2QPJ A;  4GR8 A;  1C8T A;  2XS4 A;  3F17 A;  3LEA A;  2WOA A;  3P24 A;  1XUC A;  3HDB A;  3F16 A;  3V96 B;  2MZE A;  2OVZ A;  2YIG A;  2AIG P;  1DTH A;  4JQG A;  3EDH A;  4XM8 A;  1UTZ A;  4WKI A;  2DW0 A;  4CTH A;  4AXQ A;  2FV9 A;  3NX7 A;  4H30 A;  3RTT A;  4JIJ A;  1K7Q A;  1B3D A;  5CZM A;  1BQO A;  4GWN A;  2HU6 A;  5I3M A;  2W12 A;  1GE7 A;  1RMZ A;  2Y6D A;  1JKY A;  4PKQ A;  1MNC A;  3BA0 A;  2JNP A;  4H76 A;  2OZR A;  1C3I A;  1O0Q A;  4R3V A;  4GUY A;  2D1N A;  3B92 A;  4DV8 A;  1IAC A;  1FM1 A;  1OM7 A;  1YQY A;  3LK8 A;  4JA1 A;  1S4B P;  2Z2D A;  3DWB A;  3EWJ A;  1XFV A;  1JAP A;  3WV3 A;  1BIW A;  1B8Y A;  1PWP A;  2E3X A;  3VI1 A;  1ROS A;  4HX3 A;  1IAB A;  3LUM A;  1D7X A;  3U1R A;  3HYG A;  3EDI A;  4GQL A;  5D1S A;  1GO8 P;  1PWU A;  5H8X A;  3I7G A;  4JP4 A;  4ZR5 A;  1AYK A;  4H84 A;  2O3E A;  1BKC I;  3HBU P;  3DSL A;  4Q1L A;  2W15 A; 
#chains in the Genus database with same CATH topology
 2Y6C A;  4FXQ A;  4PKV A;  3LIR A;  1QJJ A;  1IAE A;  4PKW A;  2USN A;  4XBH A;  4DD8 A;  3EDZ A;  4GF1 A;  4G9L A;  3CKI A;  3KWV C;  1L6J A;  3DNG A;  3EHY A;  3AIG A;  2OXZ A;  1GXD A;  5BOY A;  1PWW A;  1CK7 A;  1WNI A;  3LJT A;  3I7I A;  4WKE A;  4H82 A;  2D1O A;  1QUA A;  2TCL A;  5B5O A;  5I2Z A;  1MMP A;  1R1I A;  3LQ0 A;  2OW0 A;  2MLS A;  1KUI A;  4IUW A;  2CKI A;  1OM8 A;  2I47 A;  1ZXV A;  1JIW P;  2MZH A;  3Q2H A;  5CXA A;  2CLT A;  3HY9 A;  4AUO A;  1SRP A;  2N8R A;  1ND1 A;  2X7M A;  2MLR A;  2W0D A;  1CGE A;  1XM5 A;  1DMT A;  1G12 A;  3DPF A;  1G9K A;  1BUD A;  1R1J A;  3TSK A;  4PKS A;  1BM6 A;  1I76 A;  4GWM A;  3ZXH A;  2RJQ A;  1JAN A;  1G4K A;  1ZTQ A;  2A8H A;  4H2E A;  4H49 A;  4FU4 A;  3AYU A;  3USN A;  3SHI A;  1XUD A;  1G49 A;  3LMC A;  2ERO A;  3KEK A;  1CXV A;  3RTS A;  1JK3 A;  1Y93 A;  2W13 A;  1GO7 P;  2WO8 A;  3LQB A;  5I4O A;  1YCM A;  3F15 A;  1AKL A;  4A7B A;  1SAT A;  2OW1 A;  2DW2 A;  1Y0V A;  1OS2 A;  1BQQ M;  5D2B A;  1KUF A;  3KMC A;  3LJG A;  3N2U A;  1EUB A;  3DL1 A;  4JPA A;  2JT6 A;  1MMB A;  3LE9 A;  4HMA A;  1ZVX A;  4L63 A;  1CIZ A;  1IAA A;  3GBO A;  5I0L A;  3E8R A;  4QKZ A;  4GR0 A;  3LUN A;  4L7A A;  3L0V A;  3UVC A;  4I35 A;  1BSW A;  4I03 A;  1GKD A;  1YP1 A;  1HFS A;  1Z3J A;  2J83 A;  1OO9 A;  1PWV A;  2JIH A;  1CGL A;  1CQR A;  1QIA A;  3LGP A;  4XCT A;  2V4B A;  1Q3A A;  5BOT A;  3O64 A;  1ZS0 A;  2PJT A;  1A86 A;  4IN9 A;  3F1A A;  1FLS A;  1TVI A;  1HY7 A;  1UMS A;  1ATL A;  3VTG A;  2W14 A;  1CAQ A;  3O2X A;  3ZVS A;  2O36 A;  1D8M A;  2X3B A;  1KAP P;  1UMT A;  1UTT A;  1XFW A;  1KUK A;  1HFC A;  3OHL A;  966C A;  2OW9 A;  2OXU A;  1ZXC A;  4H3X A;  3OHO A;  4IJO A;  5D1T A;  5D3C A;  1I1I P;  1BKC A;  1D8F A;  1O0T A;  2DDF A;  5BPA A;  2POJ A;  3KME A;  3LIL A;  3N2V A;  1JJ9 A;  1CGF A;  2J0T A;  456C A;  1XFZ A;  1HOV A;  1JAO A;  4G0D A;  2DDY A;  4PKT A;  1C7K A;  1KUH A;  5D1U A;  3WV2 A;  5I43 A;  2FV5 A;  2E2D A;  4XM6 A;  3TS4 A;  2X3C A;  5B5P A;  2WO9 A;  5LAB A;  4AYK A;  4J4M A;  2OW2 A;  4DF9 A;  3G42 A;  1XUR A;  3WV1 A;  3P1V A;  3L0T A;  4DPE A;  2OXW A;  2DW1 A;  2OVX A;  1KUG A;  3HDA P;  4ILW D;  1K7I A;  3KHI A;  4A3W A;  3LJZ A;  1OS9 A;  4L19 A;  1QIB A;  2JSD A;  1D5J A;  3ELM A;  2KRJ A;  1XFU A;  3EDG A;  1R54 A;  2K2G A;  1HTD A;  1GE6 A;  3TVC A;  2RJP A;  4L6T A;  1QJI A;  5JMY A;  1QIC A;  1SMP A;  3MA2 A;  3B2Z A;  1R1H A;  1JH1 A;  1ZP5 A;  4GR3 A;  1JIZ A;  1MMR A;  1RM8 A;  3HB2 P;  4XM7 A;  3LIK A;  1J7N A;  1BKC E;  3AYK A;  2MZI A;  1I73 A;  1R55 A;  1KBC A;  3TT4 A;  5I12 A;  2JT5 A;  1H71 P;  4PKU A;  3DTI A;  4H1Q A;  5CUH A;  4WF6 A;  1OMJ A;  3ZUK A;  1XAX A;  3EHX A;  3HY7 A;  1YOU A;  3K7L A;  1XFX A;  1K7G A;  1IAD A;  2AYK A;  830C A;  2YB9 A;  4AIG A;  1JAQ A;  2SRT A;  3KRY A;  2ERP A;  1USN A;  4WZV A;  1G05 A;  4PKR A;  1EB6 A;  1XFY A;  1GKC A;  1UEA A;  1A85 A;  3DTK A;  2YUF A;  5D7W A;  1HV5 A;  3F18 A;  4WK7 A;  3HBV P;  3G5C A;  2L0R A;  3K7N A;  2X3A A;  1PWQ A;  1GE5 A;  1AST A;  3DPE A;  4FVL A;  1SU3 A;  3LKA A;  1AF0 A;  5L79 A;  3KEC A;  1IAG A;  1FBL A;  2OI0 A;  2ERQ A;  2OY4 A;  4ON1 A;  5L7F A;  1SLN A;  2K9C A;  3F19 A;  4FXY P;  1EAK A;  1BUV M;  3B8Z A;  1MMQ A;  1SLM A;  3Q2G A;  1BZS A;  1Y8J A;  3KEJ A;  1OM6 A;  2OY2 A;  4EFS A;  2XS3 A;  2QPJ A;  4GR8 A;  1C8T A;  2XS4 A;  3F17 A;  3LEA A;  2WOA A;  3P24 A;  1XUC A;  3HDB A;  3F16 A;  3V96 B;  2MZE A;  2OVZ A;  2YIG A;  2AIG P;  1DTH A;  4JQG A;  1OZ9 A;  3EDH A;  4XM8 A;  1UTZ A;  4WKI A;  2DW0 A;  4CTH A;  4AXQ A;  2FV9 A;  3NX7 A;  4H30 A;  3RTT A;  4JIJ A;  1K7Q A;  1B3D A;  5CZM A;  1BQO A;  4GWN A;  2HU6 A;  5I3M A;  2W12 A;  1GE7 A;  1RMZ A;  2Y6D A;  1JKY A;  4PKQ A;  1MNC A;  3BA0 A;  2JNP A;  4H76 A;  2OZR A;  1C3I A;  1O0Q A;  4R3V A;  4GUY A;  2D1N A;  3B92 A;  4DV8 A;  1IAC A;  1FM1 A;  1OM7 A;  1YQY A;  3LK8 A;  4JA1 A;  1S4B P;  2Z2D A;  3DWB A;  3EWJ A;  1XFV A;  1JAP A;  3WV3 A;  1BIW A;  1B8Y A;  1PWP A;  2E3X A;  3VI1 A;  1ROS A;  4HX3 A;  1IAB A;  3LUM A;  1D7X A;  3U1R A;  3HYG A;  3EDI A;  4GQL A;  5D1S A;  1GO8 P;  1PWU A;  3DTE A;  5H8X A;  3I7G A;  4JP4 A;  4ZR5 A;  1AYK A;  4H84 A;  2O3E A;  1BKC I;  3HBU P;  3DSL A;  4Q1L A;  2W15 A; 
#chains in the Genus database with same CATH homology
 2Y6C A;  4FXQ A;  4PKV A;  3LIR A;  1QJJ A;  1IAE A;  4PKW A;  2USN A;  4XBH A;  4DD8 A;  3EDZ A;  4GF1 A;  4G9L A;  3CKI A;  3KWV C;  1L6J A;  3DNG A;  3EHY A;  3AIG A;  2OXZ A;  1GXD A;  5BOY A;  1PWW A;  1CK7 A;  1WNI A;  3LJT A;  3I7I A;  4WKE A;  4H82 A;  2D1O A;  1QUA A;  2TCL A;  5B5O A;  5I2Z A;  1MMP A;  1R1I A;  3LQ0 A;  2OW0 A;  2MLS A;  1KUI A;  4IUW A;  2CKI A;  1OM8 A;  2I47 A;  1ZXV A;  1JIW P;  2MZH A;  3Q2H A;  5CXA A;  2CLT A;  3HY9 A;  4AUO A;  1SRP A;  2N8R A;  1ND1 A;  2X7M A;  2MLR A;  2W0D A;  1CGE A;  1DMT A;  1G12 A;  3DPF A;  1G9K A;  1BUD A;  1R1J A;  3TSK A;  4PKS A;  1BM6 A;  1I76 A;  4GWM A;  3ZXH A;  2RJQ A;  1JAN A;  1G4K A;  1ZTQ A;  2A8H A;  4H2E A;  4H49 A;  4FU4 A;  3AYU A;  3USN A;  3SHI A;  1XUD A;  1G49 A;  3LMC A;  2ERO A;  3KEK A;  1CXV A;  3RTS A;  1JK3 A;  1Y93 A;  2W13 A;  1GO7 P;  2WO8 A;  3LQB A;  5I4O A;  1YCM A;  3F15 A;  1AKL A;  4A7B A;  1SAT A;  2OW1 A;  2DW2 A;  1Y0V A;  1OS2 A;  1BQQ M;  5D2B A;  1KUF A;  3KMC A;  3LJG A;  3N2U A;  1EUB A;  3DL1 A;  4JPA A;  2JT6 A;  1MMB A;  3LE9 A;  4HMA A;  1ZVX A;  4L63 A;  1CIZ A;  1IAA A;  3GBO A;  5I0L A;  3E8R A;  4QKZ A;  4GR0 A;  3LUN A;  4L7A A;  3L0V A;  3UVC A;  4I35 A;  1BSW A;  4I03 A;  1GKD A;  1YP1 A;  1HFS A;  1Z3J A;  2J83 A;  1OO9 A;  1PWV A;  2JIH A;  1CGL A;  1CQR A;  1QIA A;  3LGP A;  4XCT A;  2V4B A;  1Q3A A;  5BOT A;  3O64 A;  1ZS0 A;  2PJT A;  1A86 A;  4IN9 A;  3F1A A;  1FLS A;  1HY7 A;  1UMS A;  1ATL A;  3VTG A;  2W14 A;  1CAQ A;  3O2X A;  3ZVS A;  2O36 A;  1D8M A;  2X3B A;  1KAP P;  1UMT A;  1UTT A;  1XFW A;  1KUK A;  1HFC A;  3OHL A;  966C A;  2OW9 A;  2OXU A;  1ZXC A;  4H3X A;  3OHO A;  4IJO A;  5D1T A;  5D3C A;  1I1I P;  1BKC A;  1D8F A;  1O0T A;  2DDF A;  5BPA A;  2POJ A;  3KME A;  3LIL A;  3N2V A;  1JJ9 A;  1CGF A;  2J0T A;  456C A;  1XFZ A;  1HOV A;  1JAO A;  4G0D A;  2DDY A;  4PKT A;  1C7K A;  1KUH A;  5D1U A;  3WV2 A;  5I43 A;  2FV5 A;  2E2D A;  4XM6 A;  3TS4 A;  2X3C A;  5B5P A;  2WO9 A;  5LAB A;  4AYK A;  4J4M A;  2OW2 A;  4DF9 A;  3G42 A;  1XUR A;  3WV1 A;  3P1V A;  3L0T A;  4DPE A;  2OXW A;  2DW1 A;  2OVX A;  1KUG A;  3HDA P;  4ILW D;  1K7I A;  3KHI A;  4A3W A;  3LJZ A;  1OS9 A;  4L19 A;  1QIB A;  2JSD A;  1D5J A;  3ELM A;  2KRJ A;  1XFU A;  3EDG A;  1R54 A;  2K2G A;  1HTD A;  1GE6 A;  3TVC A;  2RJP A;  4L6T A;  1QJI A;  5JMY A;  1QIC A;  1SMP A;  3MA2 A;  3B2Z A;  1R1H A;  1JH1 A;  1ZP5 A;  4GR3 A;  1JIZ A;  1MMR A;  1RM8 A;  3HB2 P;  4XM7 A;  3LIK A;  1J7N A;  1BKC E;  3AYK A;  2MZI A;  1I73 A;  1R55 A;  1KBC A;  3TT4 A;  5I12 A;  2JT5 A;  1H71 P;  4PKU A;  3DTI A;  4H1Q A;  5CUH A;  4WF6 A;  1OMJ A;  3ZUK A;  3EHX A;  3HY7 A;  1YOU A;  3K7L A;  1XFX A;  1K7G A;  1IAD A;  2AYK A;  830C A;  2YB9 A;  4AIG A;  1JAQ A;  2SRT A;  3KRY A;  2ERP A;  1USN A;  4WZV A;  1G05 A;  4PKR A;  1EB6 A;  1XFY A;  1GKC A;  1UEA A;  1A85 A;  3DTK A;  2YUF A;  5D7W A;  1HV5 A;  3F18 A;  4WK7 A;  3HBV P;  3G5C A;  2L0R A;  3K7N A;  2X3A A;  1PWQ A;  1GE5 A;  1AST A;  3DPE A;  4FVL A;  1SU3 A;  3LKA A;  1AF0 A;  5L79 A;  3KEC A;  1IAG A;  1FBL A;  2OI0 A;  2ERQ A;  2OY4 A;  4ON1 A;  5L7F A;  1SLN A;  2K9C A;  3F19 A;  4FXY P;  1EAK A;  1BUV M;  3B8Z A;  1MMQ A;  1SLM A;  3Q2G A;  1BZS A;  1Y8J A;  3KEJ A;  1OM6 A;  2OY2 A;  4EFS A;  2XS3 A;  2QPJ A;  4GR8 A;  1C8T A;  2XS4 A;  3F17 A;  3LEA A;  2WOA A;  3P24 A;  1XUC A;  3HDB A;  3F16 A;  3V96 B;  2MZE A;  2OVZ A;  2YIG A;  2AIG P;  1DTH A;  4JQG A;  3EDH A;  4XM8 A;  1UTZ A;  4WKI A;  2DW0 A;  4CTH A;  4AXQ A;  2FV9 A;  3NX7 A;  4H30 A;  3RTT A;  4JIJ A;  1K7Q A;  1B3D A;  5CZM A;  1BQO A;  4GWN A;  2HU6 A;  5I3M A;  2W12 A;  1GE7 A;  1RMZ A;  2Y6D A;  1JKY A;  4PKQ A;  1MNC A;  3BA0 A;  2JNP A;  4H76 A;  2OZR A;  1C3I A;  1O0Q A;  4R3V A;  4GUY A;  2D1N A;  3B92 A;  4DV8 A;  1IAC A;  1FM1 A;  1OM7 A;  1YQY A;  3LK8 A;  4JA1 A;  1S4B P;  2Z2D A;  3DWB A;  3EWJ A;  1XFV A;  1JAP A;  3WV3 A;  1BIW A;  1B8Y A;  1PWP A;  2E3X A;  3VI1 A;  1ROS A;  4HX3 A;  1IAB A;  3LUM A;  1D7X A;  3U1R A;  3HYG A;  3EDI A;  4GQL A;  5D1S A;  1GO8 P;  1PWU A;  3DTE A;  5H8X A;  3I7G A;  4JP4 A;  4ZR5 A;  1AYK A;  4H84 A;  2O3E A;  1BKC I;  3HBU P;  3DSL A;  4Q1L A;  2W15 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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