3F18A

Crystal structure of the catalytic domain of human mmp12 complexed with the inhibitor 4-fluoro-n-(2-hydroxyethyl)-n-(2-nitroso-2-oxoethyl)benzenesulfonamide
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
158
structure length
158
Chain Sequence
GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Exploring the subtleties of drug-receptor interactions: the case of matrix metalloproteinases.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Macrophage metalloelastase
total genus 43
structure length 158
sequence length 158
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2008-10-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3f18A00
1Y93A 4L6TA 3ZUKA 3HYGA 1GKDA 2DDFA 4A3WA 2W0DA 1CQRA 3HDBA 3B2ZA 1GO7P 2OXZA 4DD8A 2JT6A 1OS2A 2OXWA 1IADA 2SRTA 3B8ZA 1BUDA 1XUDA 2X3AA 4JP4A 1CGFA 3O64A 2W12A 3LKAA 3GBOA 1OM7A 5D1TA 1OMJA 1UMSA 3RTSA 4AXQA 5I2ZA 1MMRA 1OM8A 1YP1A 2YIGA 4H84A 3L0VA 4GUYA 2JNPA 1J7NA 1Y0VA 1JAQA 2W15A 1KBCA 3HBVP 4GF1A 4R3VA 1SMPA 1G49A 3V96B 3LILA 1ATLA 1KUKA 3DL1A 3LJGA 4HX3A 3U1RA 4JA1A 1FM1A 1SATA 2RJQA 1QIAA 1BSWA 3I7IA 1K7QA 2J83A 2Z2DA 4J4MA 4JPAA 1HFSA 5BOTA 1GO8P 2USNA 4PKQA 2O36A 1HOVA 1HTDA 2DW1A 1I73A 4ZR5A 1ZTQA 4AUOA 4PKWA 1MMBA 3KMEA 4FU4A 1UTTA 4DV8A 1OM6A 3TT4A 2X3CA 1OS9A 1QJJA 5LABA 1PWWA 1HFCA 3EDGA 1SLMA 1IAGA 1KAPP 1XFUA 1R1IA 2POJA 3UVCA 2OW0A 5I12A 5H8XA 3USNA 1ZP5A 3P24A 1IACA 1USNA 3KEKA 4XM6A 1Y8JA 2EROA 2J0TA 3DPFA 4AIGA 1BM6A 1UEAA 3F16A 4CTHA 966CA 5B5OA 1B3DA 3LQBA 4WZVA 4PKVA 1CGEA 2ERPA 2HU6A 3MA2A 3KRYA 3AYKA 1ZVXA 3ZXHA 4L63A 2XS3A 3L0TA 3EDIA 4EFSA 1R1HA 3G5CA 1A85A 3EHXA 3AIGA 3LUMA 5L79A 5L7FA 2DW2A 1K7GA 2WOAA 2OW2A 1UTZA 1EB6A 2MLRA 1KUFA 2ERQA 1C7KA 3KEJA 2JT5A 1FLSA 1AF0A 1CGLA 3LE9A 1ND1A 1MMPA 3TVCA 3KHIA 3I7GA 1KUIA 1JAPA 1JKYA 3K7NA 3LJTA 2DW0A 4HMAA 3DPEA 4G0DA 1B8YA 1DMTA 1XURA 1YCMA 2N8RA 1GKCA 2WO8A 2MZHA 3KECA 3VI1A 1XFXA 1BKCI 1JH1A 1JAOA 4FXYP 4ON1A 1G9KA 1GE5A 4XM7A 2W14A 1GE6A 3RTTA 3N2UA 3KMCA 1JK3A 1OO9A 3LUNA 4DF9A 2X3BA 3CKIA 4H2EA 4FXQA 1JIZA 2A8HA 3LJZA 3ELMA 1ZS0A 4XM8A 2JIHA 2Y6DA 3DWBA 4I35A 3EWJA 4H76A 2MZIA 4JIJA 1R1JA 2OW1A 2CKIA 3LGPA 1EUBA 1R55A 5D7WA 3F19A 3F18A 1XUCA 3HY9A 4XCTA 1KUGA 4IUWA 2AYKA 3OHOA 3HDAP 1JJ9A 1R54A 2TCLA 4WKIA 1SRPA 1O0QA 3TS4A 3HB2P 1GE7A 1I1IP 3EHYA 3EDZA 4PKSA 5D2BA 3NX7A 2AIGP 4XBHA 1QJIA 1S4BP 4GWNA 3DNGA 5CUHA 1BUVM 3VTGA 2DDYA 2OI0A 1RM8A 3LQ0A 3O2XA 5I4OA 1IAAA 4PKTA 3K7LA 1EAKA 830CA 3N2VA 4PKRA 4AYKA 1MMQA 4WF6A 1ROSA 1C8TA 2D1NA 1G12A 1L6JA 2I47A 3BA0A 1CAQA 5JMYA 3F15A 2FV5A 4PKUA 2WO9A 1QIBA 2CLTA 1YQYA 1D8MA 4WK7A 1RMZA 1O0TA 1ZXCA 2L0RA 1AKLA 4GR8A 5I0LA 3DSLA 1D8FA 4Q1LA 5BOYA 4DPEA 1HY7A 1CXVA 4GR3A 2Y6CA 2OZRA 1K7IA 1BKCA 3WV2A 1ASTA 2JSDA 3HY7A 2W13A 5I43A 4JQGA 3WV1A 4GQLA 4H30A 1XFZA 4G9LA 2E2DA 2MZEA 2X7MA 5I3MA 1I76A 2PJTA 3F17A 2OVXA 5D1SA 5CXAA 2OW9A 2O3EA 2V4BA 1A86A 1D5JA 1HV5A 2OY4A 2D1OA 1BIWA 1IAEA 1Q3AA 2MLSA 2QPJA 3LK8A 1PWPA 3OHLA 4H1QA 4I03A 4GWMA 3F1AA 1PWVA 1XFVA 4A7BA 1DTHA 1SLNA 4QKZA 3KWVC 4IJOA 2OXUA 1G05A 1D7XA 3ZVSA 456CA 3E8RA 1C3IA 4ILWD 3SHIA 3LIRA 5B5PA 4IN9A 3Q2HA 1PWUA 3B92A 1IABA 3LIKA 2OY2A 1G4KA 3P1VA 1XFWA 2FV9A 3TSKA 1FBLA 3AYUA 1BQQM 1GXDA 1UMTA 4H82A 1MNCA 2XS4A 1QUAA 2K2GA 4H49A 4H3XA 1AYKA 1H71P 5CZMA 4WKEA 1Z3JA 1BQOA 5BPAA 2OVZA 5D3CA 2KRJA 1PWQA 1QICA 1JANA 2YB9A 4FVLA 3LEAA 1CIZA 1YOUA 1ZXVA 3G42A 4L19A 1CK7A 1JIWP 2E3XA 3HBUP 4GR0A 1BKCE 1BZSA 5D1UA 1WNIA 3EDHA 3Q2GA 3LMCA 1KUHA 1SU3A 1XFYA 2RJPA 2K9CA 3WV3A
chains in the Genus database with same CATH superfamily
1Y93A 4L6TA 3ZUKA 3HYGA 1GKDA 2DDFA 4A3WA 2W0DA 1CQRA 3HDBA 3B2ZA 1GO7P 2OXZA 4DD8A 2JT6A 1OS2A 2OXWA 1TVIA 1IADA 2SRTA 3B8ZA 1BUDA 1XUDA 2X3AA 4JP4A 1CGFA 3O64A 2W12A 3LKAA 3GBOA 1OM7A 5D1TA 1OMJA 1UMSA 3RTSA 4AXQA 5I2ZA 1MMRA 1OM8A 1YP1A 2YIGA 4H84A 3L0VA 4GUYA 2JNPA 1J7NA 1Y0VA 1JAQA 2W15A 1KBCA 3HBVP 4GF1A 4R3VA 1SMPA 1G49A 3V96B 3LILA 1ATLA 1KUKA 3DL1A 3LJGA 4HX3A 3U1RA 4JA1A 1FM1A 1SATA 2RJQA 1QIAA 1BSWA 3I7IA 1K7QA 2J83A 2Z2DA 4J4MA 4JPAA 1HFSA 5BOTA 1GO8P 2USNA 4PKQA 2O36A 1HOVA 1HTDA 2DW1A 1I73A 4ZR5A 1ZTQA 4AUOA 4PKWA 1MMBA 3KMEA 4FU4A 1UTTA 4DV8A 1OM6A 3TT4A 2X3CA 1OS9A 1QJJA 5LABA 1PWWA 1HFCA 3DTKA 3EDGA 1SLMA 1IAGA 1KAPP 1XFUA 1R1IA 2POJA 3UVCA 2OW0A 5I12A 5H8XA 3USNA 1ZP5A 3P24A 1IACA 1USNA 3KEKA 4XM6A 4L7AA 1Y8JA 2EROA 2J0TA 3DPFA 4AIGA 1BM6A 1UEAA 3F16A 4CTHA 966CA 5B5OA 1B3DA 3LQBA 4WZVA 4PKVA 1CGEA 2ERPA 2HU6A 3MA2A 3KRYA 3AYKA 1ZVXA 3ZXHA 4L63A 2XS3A 3L0TA 3EDIA 4EFSA 1R1HA 3G5CA 1A85A 3EHXA 3AIGA 3LUMA 5L79A 5L7FA 3DTEA 2DW2A 1K7GA 2WOAA 2OW2A 1UTZA 1EB6A 3DTIA 2MLRA 1KUFA 2ERQA 1C7KA 3KEJA 2JT5A 1FLSA 1AF0A 1CGLA 3LE9A 1ND1A 1MMPA 3TVCA 3KHIA 3I7GA 1KUIA 1JAPA 1JKYA 3K7NA 3LJTA 2DW0A 4HMAA 3DPEA 4G0DA 1B8YA 1DMTA 1XURA 1YCMA 2N8RA 1GKCA 2WO8A 2MZHA 3KECA 3VI1A 1XFXA 1BKCI 1JH1A 1JAOA 4FXYP 4ON1A 1G9KA 1GE5A 4XM7A 2W14A 1GE6A 3RTTA 3N2UA 3KMCA 1JK3A 1OO9A 3LUNA 4DF9A 2X3BA 3CKIA 4H2EA 4FXQA 1JIZA 2A8HA 3LJZA 3ELMA 1ZS0A 4XM8A 2JIHA 2Y6DA 3DWBA 4I35A 3EWJA 4H76A 2MZIA 4JIJA 1R1JA 2OW1A 2CKIA 3LGPA 1EUBA 1R55A 5D7WA 3F19A 3F18A 1XUCA 3HY9A 4XCTA 1KUGA 4IUWA 2AYKA 3OHOA 3HDAP 1JJ9A 1R54A 2TCLA 4WKIA 1SRPA 1O0QA 3TS4A 3HB2P 1GE7A 1I1IP 3EHYA 3EDZA 4PKSA 5D2BA 3NX7A 2AIGP 4XBHA 1QJIA 1S4BP 4GWNA 3DNGA 5CUHA 1BUVM 3VTGA 2DDYA 2OI0A 1RM8A 3LQ0A 3O2XA 5I4OA 1IAAA 4PKTA 3K7LA 1EAKA 830CA 3N2VA 4PKRA 4AYKA 1XAXA 1MMQA 4WF6A 1ROSA 1C8TA 2D1NA 1G12A 1L6JA 2I47A 3BA0A 1CAQA 5JMYA 3F15A 2FV5A 4PKUA 2WO9A 1QIBA 2CLTA 1YQYA 1D8MA 4WK7A 1RMZA 1O0TA 1ZXCA 2L0RA 1AKLA 4GR8A 5I0LA 3DSLA 1D8FA 4Q1LA 5BOYA 4DPEA 1HY7A 1CXVA 4GR3A 2Y6CA 2OZRA 1K7IA 1BKCA 3WV2A 1ASTA 2JSDA 3HY7A 2W13A 5I43A 4JQGA 3WV1A 4GQLA 4H30A 1XFZA 4G9LA 2E2DA 2MZEA 2X7MA 5I3MA 1I76A 2PJTA 3F17A 2OVXA 5D1SA 5CXAA 2OW9A 2O3EA 2V4BA 1A86A 1D5JA 1HV5A 2OY4A 2D1OA 1OZ9A 1BIWA 1IAEA 1Q3AA 2MLSA 2QPJA 3LK8A 1PWPA 3OHLA 4H1QA 4I03A 4GWMA 3F1AA 1PWVA 1XFVA 4A7BA 1DTHA 1SLNA 4QKZA 3KWVC 4IJOA 2OXUA 1G05A 2YUFA 1D7XA 3ZVSA 456CA 3E8RA 1C3IA 4ILWD 3SHIA 3LIRA 5B5PA 4IN9A 3Q2HA 1PWUA 3B92A 1IABA 3LIKA 2OY2A 1G4KA 3P1VA 1XFWA 2FV9A 3TSKA 1FBLA 3AYUA 1BQQM 1GXDA 1UMTA 4H82A 1MNCA 2XS4A 1QUAA 2K2GA 4H49A 4H3XA 1AYKA 1H71P 5CZMA 4WKEA 1Z3JA 1BQOA 5BPAA 2OVZA 5D3CA 2KRJA 1PWQA 1QICA 1JANA 2YB9A 4FVLA 3LEAA 1CIZA 1YOUA 1ZXVA 3G42A 4L19A 1CK7A 1JIWP 2E3XA 3HBUP 4GR0A 1XM5A 1BKCE 1BZSA 5D1UA 1WNIA 3EDHA 3Q2GA 3LMCA 1KUHA 1SU3A 1XFYA 2RJPA 2K9CA 3WV3A
chains in the Genus database with same CATH topology
1Y93A 4L6TA 3ZUKA 3HYGA 1GKDA 2DDFA 4A3WA 2W0DA 1CQRA 3HDBA 3B2ZA 1GO7P 2OXZA 4DD8A 2JT6A 1OS2A 2OXWA 1IADA 2SRTA 3B8ZA 1BUDA 1XUDA 2X3AA 4JP4A 1CGFA 3O64A 2W12A 3LKAA 3GBOA 1OM7A 5D1TA 1OMJA 1UMSA 3RTSA 4AXQA 5I2ZA 1MMRA 1OM8A 1YP1A 2YIGA 4H84A 3L0VA 4GUYA 2JNPA 1J7NA 1Y0VA 1JAQA 2W15A 1KBCA 3HBVP 4GF1A 4R3VA 1SMPA 1G49A 3V96B 3LILA 1ATLA 1KUKA 3DL1A 3LJGA 4HX3A 3U1RA 4JA1A 1FM1A 1SATA 2RJQA 1QIAA 1BSWA 3I7IA 1K7QA 2J83A 2Z2DA 4J4MA 4JPAA 1HFSA 5BOTA 1GO8P 2USNA 4PKQA 2O36A 1HOVA 1HTDA 2DW1A 1I73A 4ZR5A 1ZTQA 4AUOA 4PKWA 1MMBA 3KMEA 4FU4A 1UTTA 4DV8A 1OM6A 3TT4A 2X3CA 1OS9A 1QJJA 5LABA 1PWWA 1HFCA 3DTKA 3EDGA 1SLMA 1IAGA 1KAPP 1XFUA 1R1IA 2POJA 3UVCA 2OW0A 5I12A 5H8XA 3USNA 1ZP5A 3P24A 1IACA 1USNA 3KEKA 4XM6A 4L7AA 1Y8JA 2EROA 2J0TA 3DPFA 4AIGA 1BM6A 1UEAA 3F16A 4CTHA 966CA 5B5OA 1B3DA 3LQBA 4WZVA 4PKVA 1CGEA 2ERPA 2HU6A 3MA2A 3KRYA 3AYKA 1ZVXA 3ZXHA 4L63A 2XS3A 3L0TA 3EDIA 4EFSA 1R1HA 3G5CA 1A85A 3EHXA 3AIGA 3LUMA 5L79A 5L7FA 3DTEA 2DW2A 1K7GA 2WOAA 2OW2A 1UTZA 1EB6A 3DTIA 2MLRA 1KUFA 2ERQA 1C7KA 3KEJA 2JT5A 1FLSA 1AF0A 1CGLA 3LE9A 1ND1A 1MMPA 3TVCA 3KHIA 3I7GA 1KUIA 1JAPA 1JKYA 3K7NA 3LJTA 2DW0A 4HMAA 3DPEA 4G0DA 1B8YA 1DMTA 1XURA 1YCMA 2N8RA 1GKCA 2WO8A 2MZHA 3KECA 3VI1A 1XFXA 1BKCI 1JH1A 1JAOA 4FXYP 4ON1A 1G9KA 1GE5A 4XM7A 2W14A 1GE6A 3RTTA 3N2UA 3KMCA 1JK3A 1OO9A 3LUNA 4DF9A 2X3BA 3CKIA 4H2EA 4FXQA 1JIZA 2A8HA 3LJZA 3ELMA 1ZS0A 4XM8A 2JIHA 2Y6DA 3DWBA 4I35A 3EWJA 4H76A 2MZIA 4JIJA 1R1JA 2OW1A 2CKIA 3LGPA 1EUBA 1R55A 5D7WA 3F19A 3F18A 1XUCA 3HY9A 4XCTA 1KUGA 4IUWA 2AYKA 3OHOA 3HDAP 1JJ9A 1R54A 2TCLA 4WKIA 1SRPA 1O0QA 3TS4A 3HB2P 1GE7A 1I1IP 3EHYA 3EDZA 4PKSA 5D2BA 3NX7A 2AIGP 4XBHA 1QJIA 1S4BP 4GWNA 3DNGA 5CUHA 1BUVM 3VTGA 2DDYA 2OI0A 1RM8A 3LQ0A 3O2XA 5I4OA 1IAAA 4PKTA 3K7LA 1EAKA 830CA 3N2VA 4PKRA 4AYKA 1MMQA 4WF6A 1ROSA 1C8TA 2D1NA 1G12A 1L6JA 2I47A 3BA0A 1CAQA 5JMYA 3F15A 2FV5A 4PKUA 2WO9A 1QIBA 2CLTA 1YQYA 1D8MA 4WK7A 1RMZA 1O0TA 1ZXCA 2L0RA 1AKLA 4GR8A 5I0LA 3DSLA 1D8FA 4Q1LA 5BOYA 4DPEA 1HY7A 1CXVA 4GR3A 2Y6CA 2OZRA 1K7IA 1BKCA 3WV2A 1ASTA 2JSDA 3HY7A 2W13A 5I43A 4JQGA 3WV1A 4GQLA 4H30A 1XFZA 4G9LA 2E2DA 2MZEA 2X7MA 5I3MA 1I76A 2PJTA 3F17A 2OVXA 5D1SA 5CXAA 2OW9A 2O3EA 2V4BA 1A86A 1D5JA 1HV5A 2OY4A 2D1OA 1BIWA 1IAEA 1Q3AA 2MLSA 2QPJA 3LK8A 1PWPA 3OHLA 4H1QA 4I03A 4GWMA 3F1AA 1PWVA 1XFVA 4A7BA 1DTHA 1SLNA 4QKZA 3KWVC 4IJOA 2OXUA 1G05A 2YUFA 1D7XA 3ZVSA 456CA 3E8RA 1C3IA 4ILWD 3SHIA 3LIRA 5B5PA 4IN9A 3Q2HA 1PWUA 3B92A 1IABA 3LIKA 2OY2A 1G4KA 3P1VA 1XFWA 2FV9A 3TSKA 1FBLA 3AYUA 1BQQM 1GXDA 1UMTA 4H82A 1MNCA 2XS4A 1QUAA 2K2GA 4H49A 4H3XA 1AYKA 1H71P 5CZMA 4WKEA 1Z3JA 1BQOA 5BPAA 2OVZA 5D3CA 2KRJA 1PWQA 1QICA 1JANA 2YB9A 4FVLA 3LEAA 1CIZA 1YOUA 1ZXVA 3G42A 4L19A 1CK7A 1JIWP 2E3XA 3HBUP 4GR0A 1BKCE 1BZSA 5D1UA 1WNIA 3EDHA 3Q2GA 3LMCA 1KUHA 1SU3A 1XFYA 2RJPA 2K9CA 3WV3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Y93 A;  4L6T A;  3ZUK A;  3HYG A;  1GKD A;  2DDF A;  4A3W A;  2W0D A;  1CQR A;  3HDB A;  3B2Z A;  1GO7 P;  2OXZ A;  4DD8 A;  2JT6 A;  1OS2 A;  2OXW A;  1IAD A;  2SRT A;  3B8Z A;  1BUD A;  1XUD A;  2X3A A;  4JP4 A;  1CGF A;  3O64 A;  2W12 A;  3LKA A;  3GBO A;  1OM7 A;  5D1T A;  1OMJ A;  1UMS A;  3RTS A;  4AXQ A;  5I2Z A;  1MMR A;  1OM8 A;  1YP1 A;  2YIG A;  4H84 A;  3L0V A;  4GUY A;  2JNP A;  1J7N A;  1Y0V A;  1JAQ A;  2W15 A;  1KBC A;  3HBV P;  4GF1 A;  4R3V A;  1SMP A;  1G49 A;  3V96 B;  3LIL A;  1ATL A;  1KUK A;  3DL1 A;  3LJG A;  4HX3 A;  3U1R A;  4JA1 A;  1FM1 A;  1SAT A;  2RJQ A;  1QIA A;  1BSW A;  3I7I A;  1K7Q A;  2J83 A;  2Z2D A;  4J4M A;  4JPA A;  1HFS A;  5BOT A;  1GO8 P;  2USN A;  4PKQ A;  2O36 A;  1HOV A;  1HTD A;  2DW1 A;  1I73 A;  4ZR5 A;  1ZTQ A;  4AUO A;  4PKW A;  1MMB A;  3KME A;  4FU4 A;  1UTT A;  4DV8 A;  1OM6 A;  3TT4 A;  2X3C A;  1OS9 A;  1QJJ A;  5LAB A;  1PWW A;  1HFC A;  3EDG A;  1SLM A;  1IAG A;  1KAP P;  1XFU A;  1R1I A;  2POJ A;  3UVC A;  2OW0 A;  5I12 A;  5H8X A;  3USN A;  1ZP5 A;  3P24 A;  1IAC A;  1USN A;  3KEK A;  4XM6 A;  1Y8J A;  2ERO A;  2J0T A;  3DPF A;  4AIG A;  1BM6 A;  1UEA A;  3F16 A;  4CTH A;  966C A;  5B5O A;  1B3D A;  3LQB A;  4WZV A;  4PKV A;  1CGE A;  2ERP A;  2HU6 A;  3MA2 A;  3KRY A;  3AYK A;  1ZVX A;  3ZXH A;  4L63 A;  2XS3 A;  3L0T A;  3EDI A;  4EFS A;  1R1H A;  3G5C A;  1A85 A;  3EHX A;  3AIG A;  3LUM A;  5L79 A;  5L7F A;  2DW2 A;  1K7G A;  2WOA A;  2OW2 A;  1UTZ A;  1EB6 A;  2MLR A;  1KUF A;  2ERQ A;  1C7K A;  3KEJ A;  2JT5 A;  1FLS A;  1AF0 A;  1CGL A;  3LE9 A;  1ND1 A;  1MMP A;  3TVC A;  3KHI A;  3I7G A;  1KUI A;  1JAP A;  1JKY A;  3K7N A;  3LJT A;  2DW0 A;  4HMA A;  3DPE A;  4G0D A;  1B8Y A;  1DMT A;  1XUR A;  1YCM A;  2N8R A;  1GKC A;  2WO8 A;  2MZH A;  3KEC A;  3VI1 A;  1XFX A;  1BKC I;  1JH1 A;  1JAO A;  4FXY P;  4ON1 A;  1G9K A;  1GE5 A;  4XM7 A;  2W14 A;  1GE6 A;  3RTT A;  3N2U A;  3KMC A;  1JK3 A;  1OO9 A;  3LUN A;  4DF9 A;  2X3B A;  3CKI A;  4H2E A;  4FXQ A;  1JIZ A;  2A8H A;  3LJZ A;  3ELM A;  1ZS0 A;  4XM8 A;  2JIH A;  2Y6D A;  3DWB A;  4I35 A;  3EWJ A;  4H76 A;  2MZI A;  4JIJ A;  1R1J A;  2OW1 A;  2CKI A;  3LGP A;  1EUB A;  1R55 A;  5D7W A;  3F19 A;  3F18 A;  1XUC A;  3HY9 A;  4XCT A;  1KUG A;  4IUW A;  2AYK A;  3OHO A;  3HDA P;  1JJ9 A;  1R54 A;  2TCL A;  4WKI A;  1SRP A;  1O0Q A;  3TS4 A;  3HB2 P;  1GE7 A;  1I1I P;  3EHY A;  3EDZ A;  4PKS A;  5D2B A;  3NX7 A;  2AIG P;  4XBH A;  1QJI A;  1S4B P;  4GWN A;  3DNG A;  5CUH A;  1BUV M;  3VTG A;  2DDY A;  2OI0 A;  1RM8 A;  3LQ0 A;  3O2X A;  5I4O A;  1IAA A;  4PKT A;  3K7L A;  1EAK A;  830C A;  3N2V A;  4PKR A;  4AYK A;  1MMQ A;  4WF6 A;  1ROS A;  1C8T A;  2D1N A;  1G12 A;  1L6J A;  2I47 A;  3BA0 A;  1CAQ A;  5JMY A;  3F15 A;  2FV5 A;  4PKU A;  2WO9 A;  1QIB A;  2CLT A;  1YQY A;  1D8M A;  4WK7 A;  1RMZ A;  1O0T A;  1ZXC A;  2L0R A;  1AKL A;  4GR8 A;  5I0L A;  3DSL A;  1D8F A;  4Q1L A;  5BOY A;  4DPE A;  1HY7 A;  1CXV A;  4GR3 A;  2Y6C A;  2OZR A;  1K7I A;  1BKC A;  3WV2 A;  1AST A;  2JSD A;  3HY7 A;  2W13 A;  5I43 A;  4JQG A;  3WV1 A;  4GQL A;  4H30 A;  1XFZ A;  4G9L A;  2E2D A;  2MZE A;  2X7M A;  5I3M A;  1I76 A;  2PJT A;  3F17 A;  2OVX A;  5D1S A;  5CXA A;  2OW9 A;  2O3E A;  2V4B A;  1A86 A;  1D5J A;  1HV5 A;  2OY4 A;  2D1O A;  1BIW A;  1IAE A;  1Q3A A;  2MLS A;  2QPJ A;  3LK8 A;  1PWP A;  3OHL A;  4H1Q A;  4I03 A;  4GWM A;  3F1A A;  1PWV A;  1XFV A;  4A7B A;  1DTH A;  1SLN A;  4QKZ A;  3KWV C;  4IJO A;  2OXU A;  1G05 A;  1D7X A;  3ZVS A;  456C A;  3E8R A;  1C3I A;  4ILW D;  3SHI A;  3LIR A;  5B5P A;  4IN9 A;  3Q2H A;  1PWU A;  3B92 A;  1IAB A;  3LIK A;  2OY2 A;  1G4K A;  3P1V A;  1XFW A;  2FV9 A;  3TSK A;  1FBL A;  3AYU A;  1BQQ M;  1GXD A;  1UMT A;  4H82 A;  1MNC A;  2XS4 A;  1QUA A;  2K2G A;  4H49 A;  4H3X A;  1AYK A;  1H71 P;  5CZM A;  4WKE A;  1Z3J A;  1BQO A;  5BPA A;  2OVZ A;  5D3C A;  2KRJ A;  1PWQ A;  1QIC A;  1JAN A;  2YB9 A;  4FVL A;  3LEA A;  1CIZ A;  1YOU A;  1ZXV A;  3G42 A;  4L19 A;  1CK7 A;  1JIW P;  2E3X A;  3HBU P;  4GR0 A;  1BKC E;  1BZS A;  5D1U A;  1WNI A;  3EDH A;  3Q2G A;  3LMC A;  1KUH A;  1SU3 A;  1XFY A;  2RJP A;  2K9C A;  3WV3 A; 
#chains in the Genus database with same CATH topology
 1Y93 A;  4L6T A;  3ZUK A;  3HYG A;  1GKD A;  2DDF A;  4A3W A;  2W0D A;  1CQR A;  3HDB A;  3B2Z A;  1GO7 P;  2OXZ A;  4DD8 A;  2JT6 A;  1OS2 A;  2OXW A;  1TVI A;  1IAD A;  2SRT A;  3B8Z A;  1BUD A;  1XUD A;  2X3A A;  4JP4 A;  1CGF A;  3O64 A;  2W12 A;  3LKA A;  3GBO A;  1OM7 A;  5D1T A;  1OMJ A;  1UMS A;  3RTS A;  4AXQ A;  5I2Z A;  1MMR A;  1OM8 A;  1YP1 A;  2YIG A;  4H84 A;  3L0V A;  4GUY A;  2JNP A;  1J7N A;  1Y0V A;  1JAQ A;  2W15 A;  1KBC A;  3HBV P;  4GF1 A;  4R3V A;  1SMP A;  1G49 A;  3V96 B;  3LIL A;  1ATL A;  1KUK A;  3DL1 A;  3LJG A;  4HX3 A;  3U1R A;  4JA1 A;  1FM1 A;  1SAT A;  2RJQ A;  1QIA A;  1BSW A;  3I7I A;  1K7Q A;  2J83 A;  2Z2D A;  4J4M A;  4JPA A;  1HFS A;  5BOT A;  1GO8 P;  2USN A;  4PKQ A;  2O36 A;  1HOV A;  1HTD A;  2DW1 A;  1I73 A;  4ZR5 A;  1ZTQ A;  4AUO A;  4PKW A;  1MMB A;  3KME A;  4FU4 A;  1UTT A;  4DV8 A;  1OM6 A;  3TT4 A;  2X3C A;  1OS9 A;  1QJJ A;  5LAB A;  1PWW A;  1HFC A;  3DTK A;  3EDG A;  1SLM A;  1IAG A;  1KAP P;  1XFU A;  1R1I A;  2POJ A;  3UVC A;  2OW0 A;  5I12 A;  5H8X A;  3USN A;  1ZP5 A;  3P24 A;  1IAC A;  1USN A;  3KEK A;  4XM6 A;  4L7A A;  1Y8J A;  2ERO A;  2J0T A;  3DPF A;  4AIG A;  1BM6 A;  1UEA A;  3F16 A;  4CTH A;  966C A;  5B5O A;  1B3D A;  3LQB A;  4WZV A;  4PKV A;  1CGE A;  2ERP A;  2HU6 A;  3MA2 A;  3KRY A;  3AYK A;  1ZVX A;  3ZXH A;  4L63 A;  2XS3 A;  3L0T A;  3EDI A;  4EFS A;  1R1H A;  3G5C A;  1A85 A;  3EHX A;  3AIG A;  3LUM A;  5L79 A;  5L7F A;  3DTE A;  2DW2 A;  1K7G A;  2WOA A;  2OW2 A;  1UTZ A;  1EB6 A;  3DTI A;  2MLR A;  1KUF A;  2ERQ A;  1C7K A;  3KEJ A;  2JT5 A;  1FLS A;  1AF0 A;  1CGL A;  3LE9 A;  1ND1 A;  1MMP A;  3TVC A;  3KHI A;  3I7G A;  1KUI A;  1JAP A;  1JKY A;  3K7N A;  3LJT A;  2DW0 A;  4HMA A;  3DPE A;  4G0D A;  1B8Y A;  1DMT A;  1XUR A;  1YCM A;  2N8R A;  1GKC A;  2WO8 A;  2MZH A;  3KEC A;  3VI1 A;  1XFX A;  1BKC I;  1JH1 A;  1JAO A;  4FXY P;  4ON1 A;  1G9K A;  1GE5 A;  4XM7 A;  2W14 A;  1GE6 A;  3RTT A;  3N2U A;  3KMC A;  1JK3 A;  1OO9 A;  3LUN A;  4DF9 A;  2X3B A;  3CKI A;  4H2E A;  4FXQ A;  1JIZ A;  2A8H A;  3LJZ A;  3ELM A;  1ZS0 A;  4XM8 A;  2JIH A;  2Y6D A;  3DWB A;  4I35 A;  3EWJ A;  4H76 A;  2MZI A;  4JIJ A;  1R1J A;  2OW1 A;  2CKI A;  3LGP A;  1EUB A;  1R55 A;  5D7W A;  3F19 A;  3F18 A;  1XUC A;  3HY9 A;  4XCT A;  1KUG A;  4IUW A;  2AYK A;  3OHO A;  3HDA P;  1JJ9 A;  1R54 A;  2TCL A;  4WKI A;  1SRP A;  1O0Q A;  3TS4 A;  3HB2 P;  1GE7 A;  1I1I P;  3EHY A;  3EDZ A;  4PKS A;  5D2B A;  3NX7 A;  2AIG P;  4XBH A;  1QJI A;  1S4B P;  4GWN A;  3DNG A;  5CUH A;  1BUV M;  3VTG A;  2DDY A;  2OI0 A;  1RM8 A;  3LQ0 A;  3O2X A;  5I4O A;  1IAA A;  4PKT A;  3K7L A;  1EAK A;  830C A;  3N2V A;  4PKR A;  4AYK A;  1XAX A;  1MMQ A;  4WF6 A;  1ROS A;  1C8T A;  2D1N A;  1G12 A;  1L6J A;  2I47 A;  3BA0 A;  1CAQ A;  5JMY A;  3F15 A;  2FV5 A;  4PKU A;  2WO9 A;  1QIB A;  2CLT A;  1YQY A;  1D8M A;  4WK7 A;  1RMZ A;  1O0T A;  1ZXC A;  2L0R A;  1AKL A;  4GR8 A;  5I0L A;  3DSL A;  1D8F A;  4Q1L A;  5BOY A;  4DPE A;  1HY7 A;  1CXV A;  4GR3 A;  2Y6C A;  2OZR A;  1K7I A;  1BKC A;  3WV2 A;  1AST A;  2JSD A;  3HY7 A;  2W13 A;  5I43 A;  4JQG A;  3WV1 A;  4GQL A;  4H30 A;  1XFZ A;  4G9L A;  2E2D A;  2MZE A;  2X7M A;  5I3M A;  1I76 A;  2PJT A;  3F17 A;  2OVX A;  5D1S A;  5CXA A;  2OW9 A;  2O3E A;  2V4B A;  1A86 A;  1D5J A;  1HV5 A;  2OY4 A;  2D1O A;  1OZ9 A;  1BIW A;  1IAE A;  1Q3A A;  2MLS A;  2QPJ A;  3LK8 A;  1PWP A;  3OHL A;  4H1Q A;  4I03 A;  4GWM A;  3F1A A;  1PWV A;  1XFV A;  4A7B A;  1DTH A;  1SLN A;  4QKZ A;  3KWV C;  4IJO A;  2OXU A;  1G05 A;  2YUF A;  1D7X A;  3ZVS A;  456C A;  3E8R A;  1C3I A;  4ILW D;  3SHI A;  3LIR A;  5B5P A;  4IN9 A;  3Q2H A;  1PWU A;  3B92 A;  1IAB A;  3LIK A;  2OY2 A;  1G4K A;  3P1V A;  1XFW A;  2FV9 A;  3TSK A;  1FBL A;  3AYU A;  1BQQ M;  1GXD A;  1UMT A;  4H82 A;  1MNC A;  2XS4 A;  1QUA A;  2K2G A;  4H49 A;  4H3X A;  1AYK A;  1H71 P;  5CZM A;  4WKE A;  1Z3J A;  1BQO A;  5BPA A;  2OVZ A;  5D3C A;  2KRJ A;  1PWQ A;  1QIC A;  1JAN A;  2YB9 A;  4FVL A;  3LEA A;  1CIZ A;  1YOU A;  1ZXV A;  3G42 A;  4L19 A;  1CK7 A;  1JIW P;  2E3X A;  3HBU P;  4GR0 A;  1XM5 A;  1BKC E;  1BZS A;  5D1U A;  1WNI A;  3EDH A;  3Q2G A;  3LMC A;  1KUH A;  1SU3 A;  1XFY A;  2RJP A;  2K9C A;  3WV3 A; 
#chains in the Genus database with same CATH homology
 1Y93 A;  4L6T A;  3ZUK A;  3HYG A;  1GKD A;  2DDF A;  4A3W A;  2W0D A;  1CQR A;  3HDB A;  3B2Z A;  1GO7 P;  2OXZ A;  4DD8 A;  2JT6 A;  1OS2 A;  2OXW A;  1IAD A;  2SRT A;  3B8Z A;  1BUD A;  1XUD A;  2X3A A;  4JP4 A;  1CGF A;  3O64 A;  2W12 A;  3LKA A;  3GBO A;  1OM7 A;  5D1T A;  1OMJ A;  1UMS A;  3RTS A;  4AXQ A;  5I2Z A;  1MMR A;  1OM8 A;  1YP1 A;  2YIG A;  4H84 A;  3L0V A;  4GUY A;  2JNP A;  1J7N A;  1Y0V A;  1JAQ A;  2W15 A;  1KBC A;  3HBV P;  4GF1 A;  4R3V A;  1SMP A;  1G49 A;  3V96 B;  3LIL A;  1ATL A;  1KUK A;  3DL1 A;  3LJG A;  4HX3 A;  3U1R A;  4JA1 A;  1FM1 A;  1SAT A;  2RJQ A;  1QIA A;  1BSW A;  3I7I A;  1K7Q A;  2J83 A;  2Z2D A;  4J4M A;  4JPA A;  1HFS A;  5BOT A;  1GO8 P;  2USN A;  4PKQ A;  2O36 A;  1HOV A;  1HTD A;  2DW1 A;  1I73 A;  4ZR5 A;  1ZTQ A;  4AUO A;  4PKW A;  1MMB A;  3KME A;  4FU4 A;  1UTT A;  4DV8 A;  1OM6 A;  3TT4 A;  2X3C A;  1OS9 A;  1QJJ A;  5LAB A;  1PWW A;  1HFC A;  3DTK A;  3EDG A;  1SLM A;  1IAG A;  1KAP P;  1XFU A;  1R1I A;  2POJ A;  3UVC A;  2OW0 A;  5I12 A;  5H8X A;  3USN A;  1ZP5 A;  3P24 A;  1IAC A;  1USN A;  3KEK A;  4XM6 A;  4L7A A;  1Y8J A;  2ERO A;  2J0T A;  3DPF A;  4AIG A;  1BM6 A;  1UEA A;  3F16 A;  4CTH A;  966C A;  5B5O A;  1B3D A;  3LQB A;  4WZV A;  4PKV A;  1CGE A;  2ERP A;  2HU6 A;  3MA2 A;  3KRY A;  3AYK A;  1ZVX A;  3ZXH A;  4L63 A;  2XS3 A;  3L0T A;  3EDI A;  4EFS A;  1R1H A;  3G5C A;  1A85 A;  3EHX A;  3AIG A;  3LUM A;  5L79 A;  5L7F A;  3DTE A;  2DW2 A;  1K7G A;  2WOA A;  2OW2 A;  1UTZ A;  1EB6 A;  3DTI A;  2MLR A;  1KUF A;  2ERQ A;  1C7K A;  3KEJ A;  2JT5 A;  1FLS A;  1AF0 A;  1CGL A;  3LE9 A;  1ND1 A;  1MMP A;  3TVC A;  3KHI A;  3I7G A;  1KUI A;  1JAP A;  1JKY A;  3K7N A;  3LJT A;  2DW0 A;  4HMA A;  3DPE A;  4G0D A;  1B8Y A;  1DMT A;  1XUR A;  1YCM A;  2N8R A;  1GKC A;  2WO8 A;  2MZH A;  3KEC A;  3VI1 A;  1XFX A;  1BKC I;  1JH1 A;  1JAO A;  4FXY P;  4ON1 A;  1G9K A;  1GE5 A;  4XM7 A;  2W14 A;  1GE6 A;  3RTT A;  3N2U A;  3KMC A;  1JK3 A;  1OO9 A;  3LUN A;  4DF9 A;  2X3B A;  3CKI A;  4H2E A;  4FXQ A;  1JIZ A;  2A8H A;  3LJZ A;  3ELM A;  1ZS0 A;  4XM8 A;  2JIH A;  2Y6D A;  3DWB A;  4I35 A;  3EWJ A;  4H76 A;  2MZI A;  4JIJ A;  1R1J A;  2OW1 A;  2CKI A;  3LGP A;  1EUB A;  1R55 A;  5D7W A;  3F19 A;  3F18 A;  1XUC A;  3HY9 A;  4XCT A;  1KUG A;  4IUW A;  2AYK A;  3OHO A;  3HDA P;  1JJ9 A;  1R54 A;  2TCL A;  4WKI A;  1SRP A;  1O0Q A;  3TS4 A;  3HB2 P;  1GE7 A;  1I1I P;  3EHY A;  3EDZ A;  4PKS A;  5D2B A;  3NX7 A;  2AIG P;  4XBH A;  1QJI A;  1S4B P;  4GWN A;  3DNG A;  5CUH A;  1BUV M;  3VTG A;  2DDY A;  2OI0 A;  1RM8 A;  3LQ0 A;  3O2X A;  5I4O A;  1IAA A;  4PKT A;  3K7L A;  1EAK A;  830C A;  3N2V A;  4PKR A;  4AYK A;  1MMQ A;  4WF6 A;  1ROS A;  1C8T A;  2D1N A;  1G12 A;  1L6J A;  2I47 A;  3BA0 A;  1CAQ A;  5JMY A;  3F15 A;  2FV5 A;  4PKU A;  2WO9 A;  1QIB A;  2CLT A;  1YQY A;  1D8M A;  4WK7 A;  1RMZ A;  1O0T A;  1ZXC A;  2L0R A;  1AKL A;  4GR8 A;  5I0L A;  3DSL A;  1D8F A;  4Q1L A;  5BOY A;  4DPE A;  1HY7 A;  1CXV A;  4GR3 A;  2Y6C A;  2OZR A;  1K7I A;  1BKC A;  3WV2 A;  1AST A;  2JSD A;  3HY7 A;  2W13 A;  5I43 A;  4JQG A;  3WV1 A;  4GQL A;  4H30 A;  1XFZ A;  4G9L A;  2E2D A;  2MZE A;  2X7M A;  5I3M A;  1I76 A;  2PJT A;  3F17 A;  2OVX A;  5D1S A;  5CXA A;  2OW9 A;  2O3E A;  2V4B A;  1A86 A;  1D5J A;  1HV5 A;  2OY4 A;  2D1O A;  1BIW A;  1IAE A;  1Q3A A;  2MLS A;  2QPJ A;  3LK8 A;  1PWP A;  3OHL A;  4H1Q A;  4I03 A;  4GWM A;  3F1A A;  1PWV A;  1XFV A;  4A7B A;  1DTH A;  1SLN A;  4QKZ A;  3KWV C;  4IJO A;  2OXU A;  1G05 A;  2YUF A;  1D7X A;  3ZVS A;  456C A;  3E8R A;  1C3I A;  4ILW D;  3SHI A;  3LIR A;  5B5P A;  4IN9 A;  3Q2H A;  1PWU A;  3B92 A;  1IAB A;  3LIK A;  2OY2 A;  1G4K A;  3P1V A;  1XFW A;  2FV9 A;  3TSK A;  1FBL A;  3AYU A;  1BQQ M;  1GXD A;  1UMT A;  4H82 A;  1MNC A;  2XS4 A;  1QUA A;  2K2G A;  4H49 A;  4H3X A;  1AYK A;  1H71 P;  5CZM A;  4WKE A;  1Z3J A;  1BQO A;  5BPA A;  2OVZ A;  5D3C A;  2KRJ A;  1PWQ A;  1QIC A;  1JAN A;  2YB9 A;  4FVL A;  3LEA A;  1CIZ A;  1YOU A;  1ZXV A;  3G42 A;  4L19 A;  1CK7 A;  1JIW P;  2E3X A;  3HBU P;  4GR0 A;  1BKC E;  1BZS A;  5D1U A;  1WNI A;  3EDH A;  3Q2G A;  3LMC A;  1KUH A;  1SU3 A;  1XFY A;  2RJP A;  2K9C A;  3WV3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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