3KWVC

Structural basis for the unfolding of anthrax lethal factor by protective antigen oligomers
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
222
structure length
222
Chain Sequence
NKTQEEHLKEIMKHIVKIEVKGEEAVKKEAAEKLLEKVPSDVLEMYKAIGGKIYIVDGDITKHISLEALSEDKKKIKDIYGKDALLHEHYVYAKEGYEPVLVIQSSEDYVENTEKALNVYYEIGKILSRDILSKINQPYQKFLDVLNTIKNASDSDGQDLLFTNQLKEHPTDFSVEFLEQNSNEVQEVFAKAFAYYIEPQHRDVLQLYAPEAFNYMDKFNEQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the unfolding of anthrax lethal factor by protective antigen oligomers.
pubmed doi rcsb
molecule tags Toxin/protein transport
source organism Bacillus anthracis
molecule keywords Protective antigen PA-63
total genus 51
structure length 222
sequence length 222
chains with identical sequence F
ec nomenclature ec 3.4.24.83: Anthrax lethal factor endopeptidase.
pdb deposition date 2009-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF07737 ATLF Anthrax toxin lethal factor, N- and C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3kwvC00
3KMEA 2XS4A 2FV5A 4XM8A 1OS2A 1CK7A 1IACA 3EHYA 3LIKA 1JAQA 1Y8JA 1JAPA 5D3CA 3EDZA 2N8RA 1JKYA 2W15A 1DTHA 1G4KA 4FVLA 1XFVA 4H2EA 1IAEA 3I7IA 5CUHA 1JANA 4G9LA 4H82A 5BPAA 1SATA 1UTTA 1XFWA 3TS4A 1QIBA 1MMBA 4GWMA 1CXVA 3OHLA 5LABA 5D1SA 1CGLA 3N2UA 3AYKA 1H71P 4H49A 1D7XA 3LQBA 1CGEA 1EAKA 1CIZA 3B92A 2MZEA 4HX3A 3LJTA 3AYUA 3HBVP 4PKRA 3SHIA 2OZRA 3O64A 3P24A 1KUFA 2MZHA 2Y6CA 5B5OA 4AYKA 2JT5A 4JIJA 5D2BA 4CTHA 3B2ZA 4ZR5A 3WV2A 1GO8P 1B8YA 1ZXVA 1DMTA 1L6JA 1KAPP 3P1VA 4Q1LA 3HY7A 1GE7A 1O0TA 3Q2GA 1MMPA 4EFSA 1D8MA 1QJJA 1XURA 1FLSA 3HB2P 1HFSA 2OY2A 3USNA 2XS3A 3N2VA 1I1IP 1YOUA 4QKZA 3GBOA 3F16A 2RJPA 5I43A 1SMPA 3V96B 1YCMA 1IADA 2DDFA 4L19A 2OXZA 1YQYA 5JMYA 2X7MA 4L6TA 1HOVA 1I76A 1EUBA 1K7QA 1GE5A 1UMSA 1MMQA 5D1TA 1R1HA 1BUVM 4XBHA 5CXAA 1ROSA 2SRTA 1JJ9A 3HBUP 5I3MA 3DPEA 4JA1A 2OW9A 1SU3A 4IUWA 2I47A 2D1OA 2CKIA 2OW1A 4L63A 1PWVA 2JT6A 1G49A 1XUDA 2OY4A 3Q2HA 3HY9A 2W0DA 1D5JA 3RTTA 3LKAA 3VI1A 3CKIA 2DW1A 3LQ0A 2WO9A 1JIZA 1BKCI 1PWQA 1MNCA 4H84A 3ZUKA 2TCLA 1OM6A 1R1IA 5BOTA 3I7GA 3ZVSA 1OS9A 5BOYA 3EDHA 1OM7A 5H8XA 1PWWA 4XM6A 2HU6A 1Q3AA 456CA 4FXQA 1GXDA 2X3CA 1SRPA 4H1QA 3RTSA 4AXQA 2YB9A 1HTDA 2O3EA 2W14A 3EDGA 3LUMA 1XUCA 3ZXHA 3E8RA 1G12A 4XCTA 1SLMA 1R1JA 1GKDA 1JIWP 1BSWA 3K7LA 1KUIA 2KRJA 2E3XA 3F17A 4R3VA 1IAAA 4WZVA 2DW0A 1BIWA 3DSLA 3TT4A 3NX7A 3AIGA 3OHOA 4I35A 5L79A 2E2DA 3EHXA 2CLTA 2J0TA 3LIRA 2W13A 1QUAA 5D1UA 5I2ZA 1ZTQA 4DD8A 1XFYA 1PWUA 1UEAA 2USNA 1YP1A 2Z2DA 1A86A 3KEKA 4GR8A 3LK8A 1JAOA 3DWBA 1PWPA 2EROA 1UMTA 4ILWD 4H30A 3WV1A 1XFUA 4IJOA 5I4OA 2OW2A 3BA0A 2WO8A 4G0DA 3KHIA 3DPFA 4WK7A 1KUGA 4GWNA 1FM1A 1AKLA 2A8HA 1RM8A 3KRYA 1BUDA 4GUYA 4PKTA 4H76A 4ON1A 2DW2A 4PKVA 1ZVXA 1C7KA 2K9CA 1WNIA 4DPEA 2FV9A 1Y0VA 1SLNA 1XFZA 2ERPA 2POJA 3O2XA 1D8FA 3ELMA 1BM6A 2PJTA 2W12A 4A7BA 4JP4A 2OVXA 1BKCE 4WKEA 1CQRA 1G9KA 1USNA 3HYGA 4PKUA 2OW0A 830CA 3HDAP 3LEAA 2YIGA 1ZXCA 1EB6A 2QPJA 4FU4A 1B3DA 4J4MA 2J83A 1K7IA 1HV5A 3UVCA 3MA2A 1O0QA 1ZS0A 3TVCA 3LJZA 4XM7A 1S4BP 2Y6DA 1GKCA 4DF9A 1KUHA 3U1RA 4IN9A 1KBCA 1R55A 4GF1A 4WF6A 1OM8A 2X3AA 1OO9A 1OMJA 2OVZA 3G5CA 1MMRA 2D1NA 3KEJA 4HMAA 4WKIA 1UTZA 4GR0A 4PKQA 1ASTA 1C3IA 1HFCA 1R54A 1A85A 5D7WA 1QJIA 2JSDA 3KWVC 1BZSA 2DDYA 3F19A 1G05A 2AYKA 2RJQA 2MLSA 1KUKA 2K2GA 3LUNA 1BKCA 1CGFA 4GQLA 5B5PA 3LMCA 3WV3A 1BQOA 1QIAA 1AF0A 1C8TA 1K7GA 1Y93A 3F1AA 3LILA 4JPAA 1GO7P 2OXUA 3KECA 3F18A 1ND1A 1ATLA 4DV8A 2V4BA 1ZP5A 1QICA 2JIHA 2OI0A 3DL1A 3L0VA 2JNPA 2OXWA 1Z3JA 4PKWA 3L0TA 3LE9A 2X3BA 4AIGA 5I12A 1HY7A 1J7NA 4GR3A 4FXYP 2O36A 5I0LA 3TSKA 3K7NA 4I03A 3G42A 1IAGA 2L0RA 5L7FA 966CA 2WOAA 2ERQA 3VTGA 1BQQM 3KMCA 3B8ZA 2MLRA 3LJGA 4A3WA 4PKSA 3EDIA 1XFXA 4JQGA 3DNGA 1JK3A 1RMZA 1JH1A 1I73A 3LGPA 1CAQA 3F15A 1AYKA 1GE6A 3EWJA 2MZIA 4H3XA 3HDBA 5CZMA 1FBLA 4AUOA 2AIGP 1IABA
chains in the Genus database with same CATH superfamily
3KMEA 2XS4A 1XAXA 2FV5A 4XM8A 4L7AA 1OS2A 1CK7A 1IACA 3EHYA 3LIKA 1JAQA 1Y8JA 3DTEA 1JAPA 5D3CA 3EDZA 2N8RA 1JKYA 2W15A 1DTHA 1G4KA 4FVLA 1XFVA 4H2EA 1IAEA 3I7IA 5CUHA 1JANA 4G9LA 4H82A 5BPAA 1SATA 1UTTA 1XFWA 3TS4A 1QIBA 1MMBA 4GWMA 1CXVA 3OHLA 5LABA 5D1SA 1CGLA 3N2UA 3AYKA 1H71P 4H49A 1D7XA 3LQBA 1CGEA 1EAKA 1CIZA 3B92A 3DTIA 2MZEA 4HX3A 3LJTA 3AYUA 3HBVP 4PKRA 3DTKA 3SHIA 2OZRA 3O64A 3P24A 1KUFA 2MZHA 2Y6CA 5B5OA 4AYKA 2JT5A 4JIJA 5D2BA 4CTHA 3B2ZA 4ZR5A 3WV2A 1GO8P 1B8YA 1ZXVA 1DMTA 1L6JA 1KAPP 3P1VA 4Q1LA 3HY7A 1GE7A 1O0TA 3Q2GA 1MMPA 4EFSA 1D8MA 1QJJA 1XURA 1FLSA 3HB2P 1HFSA 2OY2A 3USNA 2XS3A 3N2VA 1I1IP 1YOUA 4QKZA 3GBOA 3F16A 2RJPA 5I43A 1SMPA 3V96B 1YCMA 1IADA 2DDFA 4L19A 2OXZA 1YQYA 5JMYA 2X7MA 4L6TA 1HOVA 1I76A 1EUBA 1K7QA 1GE5A 1UMSA 1MMQA 5D1TA 1R1HA 1BUVM 4XBHA 5CXAA 1ROSA 2SRTA 1JJ9A 3HBUP 5I3MA 3DPEA 4JA1A 2OW9A 1SU3A 4IUWA 2I47A 2D1OA 2CKIA 2OW1A 4L63A 1PWVA 2JT6A 1G49A 1XUDA 2OY4A 3Q2HA 3HY9A 2W0DA 1D5JA 3RTTA 3LKAA 3VI1A 3CKIA 2DW1A 3LQ0A 2WO9A 1JIZA 1BKCI 1PWQA 1MNCA 4H84A 3ZUKA 2TCLA 1OM6A 1R1IA 5BOTA 3I7GA 3ZVSA 1OS9A 5BOYA 3EDHA 1OM7A 5H8XA 1PWWA 4XM6A 2HU6A 1Q3AA 456CA 4FXQA 1GXDA 2X3CA 1SRPA 4H1QA 3RTSA 4AXQA 2YB9A 1HTDA 2O3EA 2W14A 3EDGA 3LUMA 1XUCA 3ZXHA 3E8RA 1G12A 4XCTA 1SLMA 1R1JA 1GKDA 1JIWP 1BSWA 3K7LA 1KUIA 2KRJA 2E3XA 3F17A 4R3VA 1IAAA 4WZVA 2DW0A 1BIWA 3DSLA 3TT4A 3NX7A 3AIGA 3OHOA 4I35A 5L79A 2E2DA 3EHXA 2YUFA 2CLTA 2J0TA 3LIRA 2W13A 1QUAA 5D1UA 5I2ZA 1ZTQA 4DD8A 1XFYA 1PWUA 1UEAA 2USNA 1YP1A 2Z2DA 1A86A 3KEKA 4GR8A 3LK8A 1JAOA 3DWBA 1PWPA 2EROA 1UMTA 4ILWD 4H30A 3WV1A 1XFUA 4IJOA 5I4OA 2OW2A 3BA0A 2WO8A 4G0DA 3KHIA 3DPFA 4WK7A 1KUGA 4GWNA 1FM1A 1AKLA 2A8HA 1RM8A 3KRYA 1BUDA 4GUYA 1XM5A 4PKTA 4H76A 4ON1A 2DW2A 4PKVA 1ZVXA 1C7KA 2K9CA 1WNIA 4DPEA 2FV9A 1Y0VA 1SLNA 1XFZA 2ERPA 2POJA 3O2XA 1D8FA 3ELMA 1BM6A 2PJTA 2W12A 4A7BA 4JP4A 2OVXA 1BKCE 4WKEA 1CQRA 1G9KA 1USNA 3HYGA 4PKUA 2OW0A 830CA 3HDAP 3LEAA 2YIGA 1ZXCA 1EB6A 2QPJA 4FU4A 1B3DA 4J4MA 2J83A 1K7IA 1OZ9A 1HV5A 3UVCA 3MA2A 1O0QA 1ZS0A 3TVCA 3LJZA 4XM7A 1S4BP 2Y6DA 1GKCA 4DF9A 1KUHA 3U1RA 4IN9A 1KBCA 1R55A 4GF1A 4WF6A 1OM8A 2X3AA 1OO9A 1OMJA 2OVZA 3G5CA 1MMRA 2D1NA 3KEJA 4HMAA 4WKIA 1UTZA 4GR0A 4PKQA 1ASTA 1C3IA 1HFCA 1R54A 1A85A 5D7WA 1QJIA 2JSDA 3KWVC 1BZSA 2DDYA 3F19A 1G05A 2AYKA 2RJQA 2MLSA 1KUKA 2K2GA 3LUNA 1BKCA 1CGFA 4GQLA 5B5PA 3LMCA 3WV3A 1BQOA 1QIAA 1AF0A 1C8TA 1K7GA 1Y93A 3F1AA 3LILA 4JPAA 1GO7P 2OXUA 3KECA 3F18A 1ND1A 1ATLA 4DV8A 2V4BA 1ZP5A 1QICA 2JIHA 2OI0A 3DL1A 3L0VA 2JNPA 2OXWA 1Z3JA 4PKWA 3L0TA 3LE9A 2X3BA 4AIGA 5I12A 1HY7A 1J7NA 4GR3A 4FXYP 2O36A 5I0LA 3TSKA 3K7NA 4I03A 3G42A 1IAGA 2L0RA 5L7FA 966CA 2WOAA 2ERQA 3VTGA 1BQQM 3KMCA 3B8ZA 2MLRA 3LJGA 4A3WA 4PKSA 3EDIA 1XFXA 4JQGA 3DNGA 1JK3A 1RMZA 1JH1A 1I73A 3LGPA 1CAQA 3F15A 1TVIA 1AYKA 1GE6A 3EWJA 2MZIA 4H3XA 3HDBA 5CZMA 1FBLA 4AUOA 2AIGP 1IABA
chains in the Genus database with same CATH topology
3KMEA 2XS4A 2FV5A 4XM8A 4L7AA 1OS2A 1CK7A 1IACA 3EHYA 3LIKA 1JAQA 1Y8JA 3DTEA 1JAPA 5D3CA 3EDZA 2N8RA 1JKYA 2W15A 1DTHA 1G4KA 4FVLA 1XFVA 4H2EA 1IAEA 3I7IA 5CUHA 1JANA 4G9LA 4H82A 5BPAA 1SATA 1UTTA 1XFWA 3TS4A 1QIBA 1MMBA 4GWMA 1CXVA 3OHLA 5LABA 5D1SA 1CGLA 3N2UA 3AYKA 1H71P 4H49A 1D7XA 3LQBA 1CGEA 1EAKA 1CIZA 3B92A 3DTIA 2MZEA 4HX3A 3LJTA 3AYUA 3HBVP 4PKRA 3DTKA 3SHIA 2OZRA 3O64A 3P24A 1KUFA 2MZHA 2Y6CA 5B5OA 4AYKA 2JT5A 4JIJA 5D2BA 4CTHA 3B2ZA 4ZR5A 3WV2A 1GO8P 1B8YA 1ZXVA 1DMTA 1L6JA 1KAPP 3P1VA 4Q1LA 3HY7A 1GE7A 1O0TA 3Q2GA 1MMPA 4EFSA 1D8MA 1QJJA 1XURA 1FLSA 3HB2P 1HFSA 2OY2A 3USNA 2XS3A 3N2VA 1I1IP 1YOUA 4QKZA 3GBOA 3F16A 2RJPA 5I43A 1SMPA 3V96B 1YCMA 1IADA 2DDFA 4L19A 2OXZA 1YQYA 5JMYA 2X7MA 4L6TA 1HOVA 1I76A 1EUBA 1K7QA 1GE5A 1UMSA 1MMQA 5D1TA 1R1HA 1BUVM 4XBHA 5CXAA 1ROSA 2SRTA 1JJ9A 3HBUP 5I3MA 3DPEA 4JA1A 2OW9A 1SU3A 4IUWA 2I47A 2D1OA 2CKIA 2OW1A 4L63A 1PWVA 2JT6A 1G49A 1XUDA 2OY4A 3Q2HA 3HY9A 2W0DA 1D5JA 3RTTA 3LKAA 3VI1A 3CKIA 2DW1A 3LQ0A 2WO9A 1JIZA 1BKCI 1PWQA 1MNCA 4H84A 3ZUKA 2TCLA 1OM6A 1R1IA 5BOTA 3I7GA 3ZVSA 1OS9A 5BOYA 3EDHA 1OM7A 5H8XA 1PWWA 4XM6A 2HU6A 1Q3AA 456CA 4FXQA 1GXDA 2X3CA 1SRPA 4H1QA 3RTSA 4AXQA 2YB9A 1HTDA 2O3EA 2W14A 3EDGA 3LUMA 1XUCA 3ZXHA 3E8RA 1G12A 4XCTA 1SLMA 1R1JA 1GKDA 1JIWP 1BSWA 3K7LA 1KUIA 2KRJA 2E3XA 3F17A 4R3VA 1IAAA 4WZVA 2DW0A 1BIWA 3DSLA 3TT4A 3NX7A 3AIGA 3OHOA 4I35A 5L79A 2E2DA 3EHXA 2YUFA 2CLTA 2J0TA 3LIRA 2W13A 1QUAA 5D1UA 5I2ZA 1ZTQA 4DD8A 1XFYA 1PWUA 1UEAA 2USNA 1YP1A 2Z2DA 1A86A 3KEKA 4GR8A 3LK8A 1JAOA 3DWBA 1PWPA 2EROA 1UMTA 4ILWD 4H30A 3WV1A 1XFUA 4IJOA 5I4OA 2OW2A 3BA0A 2WO8A 4G0DA 3KHIA 3DPFA 4WK7A 1KUGA 4GWNA 1FM1A 1AKLA 2A8HA 1RM8A 3KRYA 1BUDA 4GUYA 4PKTA 4H76A 4ON1A 2DW2A 4PKVA 1ZVXA 1C7KA 2K9CA 1WNIA 4DPEA 2FV9A 1Y0VA 1SLNA 1XFZA 2ERPA 2POJA 3O2XA 1D8FA 3ELMA 1BM6A 2PJTA 2W12A 4A7BA 4JP4A 2OVXA 1BKCE 4WKEA 1CQRA 1G9KA 1USNA 3HYGA 4PKUA 2OW0A 830CA 3HDAP 3LEAA 2YIGA 1ZXCA 1EB6A 2QPJA 4FU4A 1B3DA 4J4MA 2J83A 1K7IA 1HV5A 3UVCA 3MA2A 1O0QA 1ZS0A 3TVCA 3LJZA 4XM7A 1S4BP 2Y6DA 1GKCA 4DF9A 1KUHA 3U1RA 4IN9A 1KBCA 1R55A 4GF1A 4WF6A 1OM8A 2X3AA 1OO9A 1OMJA 2OVZA 3G5CA 1MMRA 2D1NA 3KEJA 4HMAA 4WKIA 1UTZA 4GR0A 4PKQA 1ASTA 1C3IA 1HFCA 1R54A 1A85A 5D7WA 1QJIA 2JSDA 3KWVC 1BZSA 2DDYA 3F19A 1G05A 2AYKA 2RJQA 2MLSA 1KUKA 2K2GA 3LUNA 1BKCA 1CGFA 4GQLA 5B5PA 3LMCA 3WV3A 1BQOA 1QIAA 1AF0A 1C8TA 1K7GA 1Y93A 3F1AA 3LILA 4JPAA 1GO7P 2OXUA 3KECA 3F18A 1ND1A 1ATLA 4DV8A 2V4BA 1ZP5A 1QICA 2JIHA 2OI0A 3DL1A 3L0VA 2JNPA 2OXWA 1Z3JA 4PKWA 3L0TA 3LE9A 2X3BA 4AIGA 5I12A 1HY7A 1J7NA 4GR3A 4FXYP 2O36A 5I0LA 3TSKA 3K7NA 4I03A 3G42A 1IAGA 2L0RA 5L7FA 966CA 2WOAA 2ERQA 3VTGA 1BQQM 3KMCA 3B8ZA 2MLRA 3LJGA 4A3WA 4PKSA 3EDIA 1XFXA 4JQGA 3DNGA 1JK3A 1RMZA 1JH1A 1I73A 3LGPA 1CAQA 3F15A 1AYKA 1GE6A 3EWJA 2MZIA 4H3XA 3HDBA 5CZMA 1FBLA 4AUOA 2AIGP 1IABA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KME A;  2XS4 A;  2FV5 A;  4XM8 A;  1OS2 A;  1CK7 A;  1IAC A;  3EHY A;  3LIK A;  1JAQ A;  1Y8J A;  1JAP A;  5D3C A;  3EDZ A;  2N8R A;  1JKY A;  2W15 A;  1DTH A;  1G4K A;  4FVL A;  1XFV A;  4H2E A;  1IAE A;  3I7I A;  5CUH A;  1JAN A;  4G9L A;  4H82 A;  5BPA A;  1SAT A;  1UTT A;  1XFW A;  3TS4 A;  1QIB A;  1MMB A;  4GWM A;  1CXV A;  3OHL A;  5LAB A;  5D1S A;  1CGL A;  3N2U A;  3AYK A;  1H71 P;  4H49 A;  1D7X A;  3LQB A;  1CGE A;  1EAK A;  1CIZ A;  3B92 A;  2MZE A;  4HX3 A;  3LJT A;  3AYU A;  3HBV P;  4PKR A;  3SHI A;  2OZR A;  3O64 A;  3P24 A;  1KUF A;  2MZH A;  2Y6C A;  5B5O A;  4AYK A;  2JT5 A;  4JIJ A;  5D2B A;  4CTH A;  3B2Z A;  4ZR5 A;  3WV2 A;  1GO8 P;  1B8Y A;  1ZXV A;  1DMT A;  1L6J A;  1KAP P;  3P1V A;  4Q1L A;  3HY7 A;  1GE7 A;  1O0T A;  3Q2G A;  1MMP A;  4EFS A;  1D8M A;  1QJJ A;  1XUR A;  1FLS A;  3HB2 P;  1HFS A;  2OY2 A;  3USN A;  2XS3 A;  3N2V A;  1I1I P;  1YOU A;  4QKZ A;  3GBO A;  3F16 A;  2RJP A;  5I43 A;  1SMP A;  3V96 B;  1YCM A;  1IAD A;  2DDF A;  4L19 A;  2OXZ A;  1YQY A;  5JMY A;  2X7M A;  4L6T A;  1HOV A;  1I76 A;  1EUB A;  1K7Q A;  1GE5 A;  1UMS A;  1MMQ A;  5D1T A;  1R1H A;  1BUV M;  4XBH A;  5CXA A;  1ROS A;  2SRT A;  1JJ9 A;  3HBU P;  5I3M A;  3DPE A;  4JA1 A;  2OW9 A;  1SU3 A;  4IUW A;  2I47 A;  2D1O A;  2CKI A;  2OW1 A;  4L63 A;  1PWV A;  2JT6 A;  1G49 A;  1XUD A;  2OY4 A;  3Q2H A;  3HY9 A;  2W0D A;  1D5J A;  3RTT A;  3LKA A;  3VI1 A;  3CKI A;  2DW1 A;  3LQ0 A;  2WO9 A;  1JIZ A;  1BKC I;  1PWQ A;  1MNC A;  4H84 A;  3ZUK A;  2TCL A;  1OM6 A;  1R1I A;  5BOT A;  3I7G A;  3ZVS A;  1OS9 A;  5BOY A;  3EDH A;  1OM7 A;  5H8X A;  1PWW A;  4XM6 A;  2HU6 A;  1Q3A A;  456C A;  4FXQ A;  1GXD A;  2X3C A;  1SRP A;  4H1Q A;  3RTS A;  4AXQ A;  2YB9 A;  1HTD A;  2O3E A;  2W14 A;  3EDG A;  3LUM A;  1XUC A;  3ZXH A;  3E8R A;  1G12 A;  4XCT A;  1SLM A;  1R1J A;  1GKD A;  1JIW P;  1BSW A;  3K7L A;  1KUI A;  2KRJ A;  2E3X A;  3F17 A;  4R3V A;  1IAA A;  4WZV A;  2DW0 A;  1BIW A;  3DSL A;  3TT4 A;  3NX7 A;  3AIG A;  3OHO A;  4I35 A;  5L79 A;  2E2D A;  3EHX A;  2CLT A;  2J0T A;  3LIR A;  2W13 A;  1QUA A;  5D1U A;  5I2Z A;  1ZTQ A;  4DD8 A;  1XFY A;  1PWU A;  1UEA A;  2USN A;  1YP1 A;  2Z2D A;  1A86 A;  3KEK A;  4GR8 A;  3LK8 A;  1JAO A;  3DWB A;  1PWP A;  2ERO A;  1UMT A;  4ILW D;  4H30 A;  3WV1 A;  1XFU A;  4IJO A;  5I4O A;  2OW2 A;  3BA0 A;  2WO8 A;  4G0D A;  3KHI A;  3DPF A;  4WK7 A;  1KUG A;  4GWN A;  1FM1 A;  1AKL A;  2A8H A;  1RM8 A;  3KRY A;  1BUD A;  4GUY A;  4PKT A;  4H76 A;  4ON1 A;  2DW2 A;  4PKV A;  1ZVX A;  1C7K A;  2K9C A;  1WNI A;  4DPE A;  2FV9 A;  1Y0V A;  1SLN A;  1XFZ A;  2ERP A;  2POJ A;  3O2X A;  1D8F A;  3ELM A;  1BM6 A;  2PJT A;  2W12 A;  4A7B A;  4JP4 A;  2OVX A;  1BKC E;  4WKE A;  1CQR A;  1G9K A;  1USN A;  3HYG A;  4PKU A;  2OW0 A;  830C A;  3HDA P;  3LEA A;  2YIG A;  1ZXC A;  1EB6 A;  2QPJ A;  4FU4 A;  1B3D A;  4J4M A;  2J83 A;  1K7I A;  1HV5 A;  3UVC A;  3MA2 A;  1O0Q A;  1ZS0 A;  3TVC A;  3LJZ A;  4XM7 A;  1S4B P;  2Y6D A;  1GKC A;  4DF9 A;  1KUH A;  3U1R A;  4IN9 A;  1KBC A;  1R55 A;  4GF1 A;  4WF6 A;  1OM8 A;  2X3A A;  1OO9 A;  1OMJ A;  2OVZ A;  3G5C A;  1MMR A;  2D1N A;  3KEJ A;  4HMA A;  4WKI A;  1UTZ A;  4GR0 A;  4PKQ A;  1AST A;  1C3I A;  1HFC A;  1R54 A;  1A85 A;  5D7W A;  1QJI A;  2JSD A;  3KWV C;  1BZS A;  2DDY A;  3F19 A;  1G05 A;  2AYK A;  2RJQ A;  2MLS A;  1KUK A;  2K2G A;  3LUN A;  1BKC A;  1CGF A;  4GQL A;  5B5P A;  3LMC A;  3WV3 A;  1BQO A;  1QIA A;  1AF0 A;  1C8T A;  1K7G A;  1Y93 A;  3F1A A;  3LIL A;  4JPA A;  1GO7 P;  2OXU A;  3KEC A;  3F18 A;  1ND1 A;  1ATL A;  4DV8 A;  2V4B A;  1ZP5 A;  1QIC A;  2JIH A;  2OI0 A;  3DL1 A;  3L0V A;  2JNP A;  2OXW A;  1Z3J A;  4PKW A;  3L0T A;  3LE9 A;  2X3B A;  4AIG A;  5I12 A;  1HY7 A;  1J7N A;  4GR3 A;  4FXY P;  2O36 A;  5I0L A;  3TSK A;  3K7N A;  4I03 A;  3G42 A;  1IAG A;  2L0R A;  5L7F A;  966C A;  2WOA A;  2ERQ A;  3VTG A;  1BQQ M;  3KMC A;  3B8Z A;  2MLR A;  3LJG A;  4A3W A;  4PKS A;  3EDI A;  1XFX A;  4JQG A;  3DNG A;  1JK3 A;  1RMZ A;  1JH1 A;  1I73 A;  3LGP A;  1CAQ A;  3F15 A;  1AYK A;  1GE6 A;  3EWJ A;  2MZI A;  4H3X A;  3HDB A;  5CZM A;  1FBL A;  4AUO A;  2AIG P;  1IAB A; 
#chains in the Genus database with same CATH topology
 3KME A;  2XS4 A;  1XAX A;  2FV5 A;  4XM8 A;  4L7A A;  1OS2 A;  1CK7 A;  1IAC A;  3EHY A;  3LIK A;  1JAQ A;  1Y8J A;  3DTE A;  1JAP A;  5D3C A;  3EDZ A;  2N8R A;  1JKY A;  2W15 A;  1DTH A;  1G4K A;  4FVL A;  1XFV A;  4H2E A;  1IAE A;  3I7I A;  5CUH A;  1JAN A;  4G9L A;  4H82 A;  5BPA A;  1SAT A;  1UTT A;  1XFW A;  3TS4 A;  1QIB A;  1MMB A;  4GWM A;  1CXV A;  3OHL A;  5LAB A;  5D1S A;  1CGL A;  3N2U A;  3AYK A;  1H71 P;  4H49 A;  1D7X A;  3LQB A;  1CGE A;  1EAK A;  1CIZ A;  3B92 A;  3DTI A;  2MZE A;  4HX3 A;  3LJT A;  3AYU A;  3HBV P;  4PKR A;  3DTK A;  3SHI A;  2OZR A;  3O64 A;  3P24 A;  1KUF A;  2MZH A;  2Y6C A;  5B5O A;  4AYK A;  2JT5 A;  4JIJ A;  5D2B A;  4CTH A;  3B2Z A;  4ZR5 A;  3WV2 A;  1GO8 P;  1B8Y A;  1ZXV A;  1DMT A;  1L6J A;  1KAP P;  3P1V A;  4Q1L A;  3HY7 A;  1GE7 A;  1O0T A;  3Q2G A;  1MMP A;  4EFS A;  1D8M A;  1QJJ A;  1XUR A;  1FLS A;  3HB2 P;  1HFS A;  2OY2 A;  3USN A;  2XS3 A;  3N2V A;  1I1I P;  1YOU A;  4QKZ A;  3GBO A;  3F16 A;  2RJP A;  5I43 A;  1SMP A;  3V96 B;  1YCM A;  1IAD A;  2DDF A;  4L19 A;  2OXZ A;  1YQY A;  5JMY A;  2X7M A;  4L6T A;  1HOV A;  1I76 A;  1EUB A;  1K7Q A;  1GE5 A;  1UMS A;  1MMQ A;  5D1T A;  1R1H A;  1BUV M;  4XBH A;  5CXA A;  1ROS A;  2SRT A;  1JJ9 A;  3HBU P;  5I3M A;  3DPE A;  4JA1 A;  2OW9 A;  1SU3 A;  4IUW A;  2I47 A;  2D1O A;  2CKI A;  2OW1 A;  4L63 A;  1PWV A;  2JT6 A;  1G49 A;  1XUD A;  2OY4 A;  3Q2H A;  3HY9 A;  2W0D A;  1D5J A;  3RTT A;  3LKA A;  3VI1 A;  3CKI A;  2DW1 A;  3LQ0 A;  2WO9 A;  1JIZ A;  1BKC I;  1PWQ A;  1MNC A;  4H84 A;  3ZUK A;  2TCL A;  1OM6 A;  1R1I A;  5BOT A;  3I7G A;  3ZVS A;  1OS9 A;  5BOY A;  3EDH A;  1OM7 A;  5H8X A;  1PWW A;  4XM6 A;  2HU6 A;  1Q3A A;  456C A;  4FXQ A;  1GXD A;  2X3C A;  1SRP A;  4H1Q A;  3RTS A;  4AXQ A;  2YB9 A;  1HTD A;  2O3E A;  2W14 A;  3EDG A;  3LUM A;  1XUC A;  3ZXH A;  3E8R A;  1G12 A;  4XCT A;  1SLM A;  1R1J A;  1GKD A;  1JIW P;  1BSW A;  3K7L A;  1KUI A;  2KRJ A;  2E3X A;  3F17 A;  4R3V A;  1IAA A;  4WZV A;  2DW0 A;  1BIW A;  3DSL A;  3TT4 A;  3NX7 A;  3AIG A;  3OHO A;  4I35 A;  5L79 A;  2E2D A;  3EHX A;  2YUF A;  2CLT A;  2J0T A;  3LIR A;  2W13 A;  1QUA A;  5D1U A;  5I2Z A;  1ZTQ A;  4DD8 A;  1XFY A;  1PWU A;  1UEA A;  2USN A;  1YP1 A;  2Z2D A;  1A86 A;  3KEK A;  4GR8 A;  3LK8 A;  1JAO A;  3DWB A;  1PWP A;  2ERO A;  1UMT A;  4ILW D;  4H30 A;  3WV1 A;  1XFU A;  4IJO A;  5I4O A;  2OW2 A;  3BA0 A;  2WO8 A;  4G0D A;  3KHI A;  3DPF A;  4WK7 A;  1KUG A;  4GWN A;  1FM1 A;  1AKL A;  2A8H A;  1RM8 A;  3KRY A;  1BUD A;  4GUY A;  1XM5 A;  4PKT A;  4H76 A;  4ON1 A;  2DW2 A;  4PKV A;  1ZVX A;  1C7K A;  2K9C A;  1WNI A;  4DPE A;  2FV9 A;  1Y0V A;  1SLN A;  1XFZ A;  2ERP A;  2POJ A;  3O2X A;  1D8F A;  3ELM A;  1BM6 A;  2PJT A;  2W12 A;  4A7B A;  4JP4 A;  2OVX A;  1BKC E;  4WKE A;  1CQR A;  1G9K A;  1USN A;  3HYG A;  4PKU A;  2OW0 A;  830C A;  3HDA P;  3LEA A;  2YIG A;  1ZXC A;  1EB6 A;  2QPJ A;  4FU4 A;  1B3D A;  4J4M A;  2J83 A;  1K7I A;  1OZ9 A;  1HV5 A;  3UVC A;  3MA2 A;  1O0Q A;  1ZS0 A;  3TVC A;  3LJZ A;  4XM7 A;  1S4B P;  2Y6D A;  1GKC A;  4DF9 A;  1KUH A;  3U1R A;  4IN9 A;  1KBC A;  1R55 A;  4GF1 A;  4WF6 A;  1OM8 A;  2X3A A;  1OO9 A;  1OMJ A;  2OVZ A;  3G5C A;  1MMR A;  2D1N A;  3KEJ A;  4HMA A;  4WKI A;  1UTZ A;  4GR0 A;  4PKQ A;  1AST A;  1C3I A;  1HFC A;  1R54 A;  1A85 A;  5D7W A;  1QJI A;  2JSD A;  3KWV C;  1BZS A;  2DDY A;  3F19 A;  1G05 A;  2AYK A;  2RJQ A;  2MLS A;  1KUK A;  2K2G A;  3LUN A;  1BKC A;  1CGF A;  4GQL A;  5B5P A;  3LMC A;  3WV3 A;  1BQO A;  1QIA A;  1AF0 A;  1C8T A;  1K7G A;  1Y93 A;  3F1A A;  3LIL A;  4JPA A;  1GO7 P;  2OXU A;  3KEC A;  3F18 A;  1ND1 A;  1ATL A;  4DV8 A;  2V4B A;  1ZP5 A;  1QIC A;  2JIH A;  2OI0 A;  3DL1 A;  3L0V A;  2JNP A;  2OXW A;  1Z3J A;  4PKW A;  3L0T A;  3LE9 A;  2X3B A;  4AIG A;  5I12 A;  1HY7 A;  1J7N A;  4GR3 A;  4FXY P;  2O36 A;  5I0L A;  3TSK A;  3K7N A;  4I03 A;  3G42 A;  1IAG A;  2L0R A;  5L7F A;  966C A;  2WOA A;  2ERQ A;  3VTG A;  1BQQ M;  3KMC A;  3B8Z A;  2MLR A;  3LJG A;  4A3W A;  4PKS A;  3EDI A;  1XFX A;  4JQG A;  3DNG A;  1JK3 A;  1RMZ A;  1JH1 A;  1I73 A;  3LGP A;  1CAQ A;  3F15 A;  1TVI A;  1AYK A;  1GE6 A;  3EWJ A;  2MZI A;  4H3X A;  3HDB A;  5CZM A;  1FBL A;  4AUO A;  2AIG P;  1IAB A; 
#chains in the Genus database with same CATH homology
 3KME A;  2XS4 A;  2FV5 A;  4XM8 A;  4L7A A;  1OS2 A;  1CK7 A;  1IAC A;  3EHY A;  3LIK A;  1JAQ A;  1Y8J A;  3DTE A;  1JAP A;  5D3C A;  3EDZ A;  2N8R A;  1JKY A;  2W15 A;  1DTH A;  1G4K A;  4FVL A;  1XFV A;  4H2E A;  1IAE A;  3I7I A;  5CUH A;  1JAN A;  4G9L A;  4H82 A;  5BPA A;  1SAT A;  1UTT A;  1XFW A;  3TS4 A;  1QIB A;  1MMB A;  4GWM A;  1CXV A;  3OHL A;  5LAB A;  5D1S A;  1CGL A;  3N2U A;  3AYK A;  1H71 P;  4H49 A;  1D7X A;  3LQB A;  1CGE A;  1EAK A;  1CIZ A;  3B92 A;  3DTI A;  2MZE A;  4HX3 A;  3LJT A;  3AYU A;  3HBV P;  4PKR A;  3DTK A;  3SHI A;  2OZR A;  3O64 A;  3P24 A;  1KUF A;  2MZH A;  2Y6C A;  5B5O A;  4AYK A;  2JT5 A;  4JIJ A;  5D2B A;  4CTH A;  3B2Z A;  4ZR5 A;  3WV2 A;  1GO8 P;  1B8Y A;  1ZXV A;  1DMT A;  1L6J A;  1KAP P;  3P1V A;  4Q1L A;  3HY7 A;  1GE7 A;  1O0T A;  3Q2G A;  1MMP A;  4EFS A;  1D8M A;  1QJJ A;  1XUR A;  1FLS A;  3HB2 P;  1HFS A;  2OY2 A;  3USN A;  2XS3 A;  3N2V A;  1I1I P;  1YOU A;  4QKZ A;  3GBO A;  3F16 A;  2RJP A;  5I43 A;  1SMP A;  3V96 B;  1YCM A;  1IAD A;  2DDF A;  4L19 A;  2OXZ A;  1YQY A;  5JMY A;  2X7M A;  4L6T A;  1HOV A;  1I76 A;  1EUB A;  1K7Q A;  1GE5 A;  1UMS A;  1MMQ A;  5D1T A;  1R1H A;  1BUV M;  4XBH A;  5CXA A;  1ROS A;  2SRT A;  1JJ9 A;  3HBU P;  5I3M A;  3DPE A;  4JA1 A;  2OW9 A;  1SU3 A;  4IUW A;  2I47 A;  2D1O A;  2CKI A;  2OW1 A;  4L63 A;  1PWV A;  2JT6 A;  1G49 A;  1XUD A;  2OY4 A;  3Q2H A;  3HY9 A;  2W0D A;  1D5J A;  3RTT A;  3LKA A;  3VI1 A;  3CKI A;  2DW1 A;  3LQ0 A;  2WO9 A;  1JIZ A;  1BKC I;  1PWQ A;  1MNC A;  4H84 A;  3ZUK A;  2TCL A;  1OM6 A;  1R1I A;  5BOT A;  3I7G A;  3ZVS A;  1OS9 A;  5BOY A;  3EDH A;  1OM7 A;  5H8X A;  1PWW A;  4XM6 A;  2HU6 A;  1Q3A A;  456C A;  4FXQ A;  1GXD A;  2X3C A;  1SRP A;  4H1Q A;  3RTS A;  4AXQ A;  2YB9 A;  1HTD A;  2O3E A;  2W14 A;  3EDG A;  3LUM A;  1XUC A;  3ZXH A;  3E8R A;  1G12 A;  4XCT A;  1SLM A;  1R1J A;  1GKD A;  1JIW P;  1BSW A;  3K7L A;  1KUI A;  2KRJ A;  2E3X A;  3F17 A;  4R3V A;  1IAA A;  4WZV A;  2DW0 A;  1BIW A;  3DSL A;  3TT4 A;  3NX7 A;  3AIG A;  3OHO A;  4I35 A;  5L79 A;  2E2D A;  3EHX A;  2YUF A;  2CLT A;  2J0T A;  3LIR A;  2W13 A;  1QUA A;  5D1U A;  5I2Z A;  1ZTQ A;  4DD8 A;  1XFY A;  1PWU A;  1UEA A;  2USN A;  1YP1 A;  2Z2D A;  1A86 A;  3KEK A;  4GR8 A;  3LK8 A;  1JAO A;  3DWB A;  1PWP A;  2ERO A;  1UMT A;  4ILW D;  4H30 A;  3WV1 A;  1XFU A;  4IJO A;  5I4O A;  2OW2 A;  3BA0 A;  2WO8 A;  4G0D A;  3KHI A;  3DPF A;  4WK7 A;  1KUG A;  4GWN A;  1FM1 A;  1AKL A;  2A8H A;  1RM8 A;  3KRY A;  1BUD A;  4GUY A;  4PKT A;  4H76 A;  4ON1 A;  2DW2 A;  4PKV A;  1ZVX A;  1C7K A;  2K9C A;  1WNI A;  4DPE A;  2FV9 A;  1Y0V A;  1SLN A;  1XFZ A;  2ERP A;  2POJ A;  3O2X A;  1D8F A;  3ELM A;  1BM6 A;  2PJT A;  2W12 A;  4A7B A;  4JP4 A;  2OVX A;  1BKC E;  4WKE A;  1CQR A;  1G9K A;  1USN A;  3HYG A;  4PKU A;  2OW0 A;  830C A;  3HDA P;  3LEA A;  2YIG A;  1ZXC A;  1EB6 A;  2QPJ A;  4FU4 A;  1B3D A;  4J4M A;  2J83 A;  1K7I A;  1HV5 A;  3UVC A;  3MA2 A;  1O0Q A;  1ZS0 A;  3TVC A;  3LJZ A;  4XM7 A;  1S4B P;  2Y6D A;  1GKC A;  4DF9 A;  1KUH A;  3U1R A;  4IN9 A;  1KBC A;  1R55 A;  4GF1 A;  4WF6 A;  1OM8 A;  2X3A A;  1OO9 A;  1OMJ A;  2OVZ A;  3G5C A;  1MMR A;  2D1N A;  3KEJ A;  4HMA A;  4WKI A;  1UTZ A;  4GR0 A;  4PKQ A;  1AST A;  1C3I A;  1HFC A;  1R54 A;  1A85 A;  5D7W A;  1QJI A;  2JSD A;  3KWV C;  1BZS A;  2DDY A;  3F19 A;  1G05 A;  2AYK A;  2RJQ A;  2MLS A;  1KUK A;  2K2G A;  3LUN A;  1BKC A;  1CGF A;  4GQL A;  5B5P A;  3LMC A;  3WV3 A;  1BQO A;  1QIA A;  1AF0 A;  1C8T A;  1K7G A;  1Y93 A;  3F1A A;  3LIL A;  4JPA A;  1GO7 P;  2OXU A;  3KEC A;  3F18 A;  1ND1 A;  1ATL A;  4DV8 A;  2V4B A;  1ZP5 A;  1QIC A;  2JIH A;  2OI0 A;  3DL1 A;  3L0V A;  2JNP A;  2OXW A;  1Z3J A;  4PKW A;  3L0T A;  3LE9 A;  2X3B A;  4AIG A;  5I12 A;  1HY7 A;  1J7N A;  4GR3 A;  4FXY P;  2O36 A;  5I0L A;  3TSK A;  3K7N A;  4I03 A;  3G42 A;  1IAG A;  2L0R A;  5L7F A;  966C A;  2WOA A;  2ERQ A;  3VTG A;  1BQQ M;  3KMC A;  3B8Z A;  2MLR A;  3LJG A;  4A3W A;  4PKS A;  3EDI A;  1XFX A;  4JQG A;  3DNG A;  1JK3 A;  1RMZ A;  1JH1 A;  1I73 A;  3LGP A;  1CAQ A;  3F15 A;  1AYK A;  1GE6 A;  3EWJ A;  2MZI A;  4H3X A;  3HDB A;  5CZM A;  1FBL A;  4AUO A;  2AIG P;  1IAB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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