3L0TA

Crystal structure of catalytic domain of tace with hydantoin inhibitor
Total Genus 81
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
257
structure length
254
Chain Sequence
PDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYGGSPSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
publication title Discovery and SAR of hydantoin TACE inhibitors.
pubmed doi rcsb
molecule keywords Disintegrin and metalloproteinase domain-containing protein
total genus 81
structure length 254
sequence length 257
chains with identical sequence B
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2009-12-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3l0tA00
3HY7A 3G42A 3OHLA 1GO8P 4PKVA 2DW1A 2L0RA 5B5OA 4WKEA 3N2UA 4DF9A 4CTHA 1ATLA 1C3IA 4AYKA 4ILWD 2WO9A 1DTHA 1Y93A 2D1OA 4DPEA 1MNCA 1XUCA 2FV9A 2FV5A 1CGEA 3TT4A 3B2ZA 1QJIA 2DDYA 4H1QA 1CAQA 3SHIA 1GE5A 1PWVA 1ZS0A 2DW0A 5D1UA 4IJOA 3N2VA 1YCMA 3LILA 1GO7P 3LJGA 2AYKA 1YOUA 1XUDA 4XM8A 2D1NA 1R55A 3WV3A 1SATA 1BKCE 1RM8A 2W13A 3HDAP 2MLSA 3BA0A 4FXQA 3E8RA 3ZVSA 1IAAA 2XS4A 1MMRA 5I43A 1MMPA 3F15A 1B8YA 2CLTA 1GKCA 1XFVA 3F19A 1JK3A 1MMQA 2WO8A 4XCTA 1MMBA 1KUKA 2YB9A 1GE6A 3CKIA 1HV5A 1XFUA 2O36A 3HDBA 3HBUP 1OS2A 2MLRA 1R1IA 2TCLA 1SU3A 3G5CA 3LGPA 1BKCA 1G9KA 2HU6A 2Z2DA 1RMZA 4Q1LA 4FU4A 1JKYA 1UMSA 1HFSA 1OM7A 5L7FA 1Z3JA 4QKZA 3NX7A 2ERPA 3EWJA 2JT5A 2X7MA 2MZHA 5I0LA 3ZXHA 1AYKA 5BOYA 1HFCA 2MZEA 1CQRA 1KUIA 4G9LA 1ND1A 3L0TA 1K7GA 3LMCA 3U1RA 4IUWA 1BKCI 5I12A 1K7IA 2SRTA 1EUBA 3KMCA 1IABA 1YP1A 3P1VA 1EB6A 3LIKA 3EDGA 4GWNA 1XURA 2J0TA 1O0TA 4WZVA 4I35A 1HOVA 3K7NA 1ASTA 1I1IP 3DNGA 3EDIA 3RTTA 3DL1A 1OO9A 3B8ZA 4JPAA 4GUYA 2OI0A 3LIRA 2OW1A 1UTTA 2W0DA 1JIZA 3HY9A 2E3XA 2W15A 1K7QA 3LQ0A 1BQOA 1IAEA 5D1SA 4J4MA 1G49A 3LUMA 5I3MA 3F1AA 2OXUA 4PKRA 1I76A 5D1TA 2MZIA 1CGLA 3MA2A 4I03A 5H8XA 1JIWP 2OVZA 3USNA 1S4BP 2DDFA 966CA 2OY2A 1SLNA 1Y8JA 2W14A 3EHYA 1IADA 1ZTQA 5LABA 4XBHA 1JANA 2X3CA 2POJA 3F17A 3LK8A 4ON1A 5I4OA 1QJJA 3KEJA 1ROSA 2CKIA 5CZMA 4L63A 3I7GA 5D3CA 4PKUA 1GKDA 1PWQA 4XM6A 4EFSA 1JJ9A 2PJTA 1UMTA 1KUHA 3O64A 4H82A 1B3DA 1CGFA 1FBLA 5BOTA 2OXWA 3TS4A 1O0QA 1A85A 4GF1A 3EDHA 1BQQM 2QPJA 1AKLA 4AIGA 1XFXA 3DPFA 3KECA 1HTDA 5L79A 1HY7A 3UVCA 4H49A 1GXDA 1I73A 1EAKA 4AXQA 3AYUA 3RTSA 1QICA 2EROA 1XFZA 1BSWA 3LEAA 2Y6CA 1WNIA 2WOAA 2OZRA 3P24A 3DPEA 3Q2HA 3I7IA 3Q2GA 1JAPA 2OY4A 4HX3A 1OM8A 1IAGA 2O3EA 1XFYA 2ERQA 3KWVC 3HYGA 1CXVA 3WV1A 4H76A 5BPAA 3HBVP 1ZXVA 4H30A 1PWWA 1BUDA 3ELMA 3TVCA 2X3AA 1BIWA 1ZXCA 4PKSA 3L0VA 3K7LA 2DW2A 1QIAA 3V96B 4XM7A 1SMPA 4AUOA 2W12A 4WK7A 1OMJA 3F18A 3LJTA 1CK7A 3KEKA 3HB2P 1QIBA 1FM1A 3DSLA 4GR3A 4GQLA 1C8TA 4WF6A 1A86A 5B5PA 1R54A 1OM6A 1JAQA 2N8RA 1GE7A 1D5JA 1D8FA 1CIZA 3LUNA 4L6TA 1AF0A 2E2DA 1Q3AA 3EDZA 1FLSA 2OW0A 5D2BA 1BZSA 1KUFA 2K9CA 1SRPA 1D8MA 830CA 4PKQA 3LQBA 3LE9A 3B92A 3AYKA 2A8HA 1QUAA 4A3WA 4G0DA 1JAOA 4GR8A 4H2EA 1XFWA 5I2ZA 2Y6DA 4A7BA 4H3XA 3KMEA 3OHOA 2K2GA 2YIGA 2OW9A 3KRYA 1R1JA 4H84A 4JIJA 4DV8A 4L19A 456CA 1KUGA 3AIGA 3EHXA 1J7NA 1KAPP 1D7XA 3F16A 2JIHA 2V4BA 5CXAA 1Y0VA 2X3BA 1UTZA 3O2XA 3VTGA 1G4KA 4PKTA 5D7WA 4ZR5A 1UEAA 1YQYA 4HMAA 3LKAA 4R3VA 3DWBA 2OVXA 4WKIA 1ZVXA 4JP4A 1H71P 3VI1A 4GR0A 3ZUKA 4IN9A 1KBCA 1SLMA 2KRJA 1BUVM 4PKWA 3GBOA 4FXYP 4DD8A 2J83A 2XS3A 3TSKA 2I47A 2JT6A 1DMTA 1PWPA 4GWMA 1C7KA 1R1HA 2OW2A 4FVLA 2JNPA 2RJPA 3KHIA 3LJZA 3WV2A 1ZP5A 2RJQA 5JMYA 1L6JA 1BM6A 4JA1A 2USNA 5CUHA 1PWUA 1OS9A 1G12A 1IACA 2JSDA 2AIGP 2OXZA 1USNA 1G05A 4JQGA 1JH1A
chains in the Genus database with same CATH superfamily
3HY7A 3G42A 3OHLA 1GO8P 4PKVA 2DW1A 2L0RA 5B5OA 4WKEA 3N2UA 4DF9A 4CTHA 1ATLA 1C3IA 4AYKA 4ILWD 2WO9A 1DTHA 1Y93A 2D1OA 4DPEA 1MNCA 1XUCA 2FV9A 2FV5A 1CGEA 3TT4A 3B2ZA 1QJIA 2DDYA 4H1QA 1CAQA 3SHIA 1GE5A 1PWVA 1ZS0A 2DW0A 5D1UA 4IJOA 3N2VA 1YCMA 3LILA 1GO7P 3LJGA 3DTEA 2AYKA 1YOUA 1XUDA 4XM8A 2D1NA 1R55A 3WV3A 1SATA 1BKCE 1RM8A 2W13A 3HDAP 2MLSA 3BA0A 4FXQA 3E8RA 3ZVSA 1IAAA 2XS4A 1MMRA 5I43A 1MMPA 3F15A 1B8YA 2CLTA 1GKCA 1XFVA 3F19A 1JK3A 1MMQA 2WO8A 4XCTA 1MMBA 1KUKA 2YB9A 1GE6A 3CKIA 1HV5A 1XFUA 2O36A 3HDBA 3HBUP 1OS2A 2MLRA 1R1IA 2TCLA 1SU3A 3G5CA 3LGPA 1BKCA 1G9KA 2HU6A 2Z2DA 1RMZA 4Q1LA 4FU4A 1JKYA 1UMSA 1HFSA 1OM7A 5L7FA 1Z3JA 4QKZA 2YUFA 3NX7A 1XAXA 2ERPA 3EWJA 2JT5A 2X7MA 2MZHA 5I0LA 3ZXHA 1AYKA 5BOYA 1HFCA 2MZEA 1CQRA 1KUIA 4G9LA 1ND1A 3L0TA 1K7GA 3LMCA 3U1RA 4IUWA 1BKCI 5I12A 1K7IA 2SRTA 1EUBA 3KMCA 1IABA 1YP1A 3P1VA 1EB6A 3LIKA 3EDGA 4GWNA 1XURA 2J0TA 1O0TA 4WZVA 4I35A 1HOVA 3K7NA 1ASTA 1I1IP 3DNGA 3EDIA 3RTTA 3DL1A 1OO9A 3B8ZA 4JPAA 4GUYA 2OI0A 3LIRA 2OW1A 1UTTA 2W0DA 1JIZA 3HY9A 2E3XA 1OZ9A 2W15A 1K7QA 3LQ0A 1BQOA 1IAEA 5D1SA 4J4MA 1G49A 3LUMA 5I3MA 3F1AA 2OXUA 4PKRA 1I76A 5D1TA 2MZIA 1CGLA 3MA2A 4I03A 5H8XA 1JIWP 2OVZA 3USNA 1S4BP 2DDFA 1XM5A 966CA 2OY2A 1SLNA 1Y8JA 2W14A 3EHYA 1IADA 1ZTQA 5LABA 4XBHA 1JANA 2X3CA 2POJA 3F17A 3LK8A 4ON1A 5I4OA 1QJJA 3KEJA 1ROSA 2CKIA 5CZMA 4L63A 3I7GA 5D3CA 4PKUA 1GKDA 1PWQA 4XM6A 4EFSA 1JJ9A 2PJTA 1UMTA 1KUHA 3O64A 4H82A 1B3DA 1CGFA 1FBLA 5BOTA 2OXWA 3TS4A 1O0QA 1A85A 4GF1A 3EDHA 1BQQM 2QPJA 1AKLA 4AIGA 1XFXA 3DPFA 3KECA 1HTDA 5L79A 1HY7A 3UVCA 4H49A 1GXDA 1I73A 1EAKA 4AXQA 3AYUA 3RTSA 1QICA 3DTKA 2EROA 1XFZA 1BSWA 3LEAA 2Y6CA 1WNIA 2WOAA 2OZRA 3P24A 3DPEA 3Q2HA 3I7IA 3Q2GA 1JAPA 2OY4A 4HX3A 1OM8A 1IAGA 2O3EA 1XFYA 2ERQA 3KWVC 3HYGA 1CXVA 3WV1A 4H76A 5BPAA 3HBVP 1ZXVA 4H30A 1PWWA 1BUDA 3ELMA 3TVCA 2X3AA 1BIWA 1ZXCA 4PKSA 3L0VA 3K7LA 2DW2A 1QIAA 3V96B 4XM7A 1SMPA 4AUOA 2W12A 4WK7A 1OMJA 3F18A 3LJTA 1CK7A 3KEKA 3HB2P 1QIBA 1FM1A 3DSLA 4GR3A 4GQLA 1C8TA 4WF6A 1A86A 5B5PA 1R54A 1OM6A 1JAQA 2N8RA 1GE7A 1D5JA 1D8FA 1CIZA 3LUNA 4L6TA 1AF0A 4L7AA 2E2DA 1Q3AA 3EDZA 1FLSA 2OW0A 5D2BA 1BZSA 1KUFA 2K9CA 1SRPA 1D8MA 830CA 4PKQA 3LQBA 3LE9A 3B92A 3AYKA 2A8HA 1QUAA 4A3WA 4G0DA 1JAOA 4GR8A 4H2EA 1XFWA 5I2ZA 2Y6DA 4A7BA 4H3XA 3KMEA 3OHOA 2K2GA 2YIGA 2OW9A 3KRYA 1R1JA 4H84A 4JIJA 4DV8A 4L19A 456CA 1KUGA 3AIGA 3EHXA 1J7NA 1KAPP 1D7XA 3F16A 2JIHA 2V4BA 5CXAA 1Y0VA 2X3BA 1UTZA 3O2XA 3VTGA 1G4KA 4PKTA 5D7WA 4ZR5A 1UEAA 1YQYA 4HMAA 3DTIA 3LKAA 4R3VA 3DWBA 2OVXA 4WKIA 1ZVXA 4JP4A 1H71P 3VI1A 4GR0A 3ZUKA 4IN9A 1KBCA 1SLMA 2KRJA 1BUVM 4PKWA 3GBOA 4FXYP 4DD8A 2J83A 2XS3A 3TSKA 2I47A 2JT6A 1DMTA 1PWPA 4GWMA 1C7KA 1R1HA 2OW2A 4FVLA 2JNPA 2RJPA 3KHIA 3LJZA 3WV2A 1ZP5A 1TVIA 2RJQA 5JMYA 1L6JA 1BM6A 4JA1A 2USNA 5CUHA 1PWUA 1OS9A 1G12A 1IACA 2JSDA 2AIGP 2OXZA 1USNA 1G05A 4JQGA 1JH1A
chains in the Genus database with same CATH topology
3HY7A 3G42A 3OHLA 1GO8P 4PKVA 2DW1A 2L0RA 5B5OA 4WKEA 3N2UA 4DF9A 4CTHA 1ATLA 1C3IA 4AYKA 4ILWD 2WO9A 1DTHA 1Y93A 2D1OA 4DPEA 1MNCA 1XUCA 2FV9A 2FV5A 1CGEA 3TT4A 3B2ZA 1QJIA 2DDYA 4H1QA 1CAQA 3SHIA 1GE5A 1PWVA 1ZS0A 2DW0A 5D1UA 4IJOA 3N2VA 1YCMA 3LILA 1GO7P 3LJGA 3DTEA 2AYKA 1YOUA 1XUDA 4XM8A 2D1NA 1R55A 3WV3A 1SATA 1BKCE 1RM8A 2W13A 3HDAP 2MLSA 3BA0A 4FXQA 3E8RA 3ZVSA 1IAAA 2XS4A 1MMRA 5I43A 1MMPA 3F15A 1B8YA 2CLTA 1GKCA 1XFVA 3F19A 1JK3A 1MMQA 2WO8A 4XCTA 1MMBA 1KUKA 2YB9A 1GE6A 3CKIA 1HV5A 1XFUA 2O36A 3HDBA 3HBUP 1OS2A 2MLRA 1R1IA 2TCLA 1SU3A 3G5CA 3LGPA 1BKCA 1G9KA 2HU6A 2Z2DA 1RMZA 4Q1LA 4FU4A 1JKYA 1UMSA 1HFSA 1OM7A 5L7FA 1Z3JA 4QKZA 2YUFA 3NX7A 2ERPA 3EWJA 2JT5A 2X7MA 2MZHA 5I0LA 3ZXHA 1AYKA 5BOYA 1HFCA 2MZEA 1CQRA 1KUIA 4G9LA 1ND1A 3L0TA 1K7GA 3LMCA 3U1RA 4IUWA 1BKCI 5I12A 1K7IA 2SRTA 1EUBA 3KMCA 1IABA 1YP1A 3P1VA 1EB6A 3LIKA 3EDGA 4GWNA 1XURA 2J0TA 1O0TA 4WZVA 4I35A 1HOVA 3K7NA 1ASTA 1I1IP 3DNGA 3EDIA 3RTTA 3DL1A 1OO9A 3B8ZA 4JPAA 4GUYA 2OI0A 3LIRA 2OW1A 1UTTA 2W0DA 1JIZA 3HY9A 2E3XA 2W15A 1K7QA 3LQ0A 1BQOA 1IAEA 5D1SA 4J4MA 1G49A 3LUMA 5I3MA 3F1AA 2OXUA 4PKRA 1I76A 5D1TA 2MZIA 1CGLA 3MA2A 4I03A 5H8XA 1JIWP 2OVZA 3USNA 1S4BP 2DDFA 966CA 2OY2A 1SLNA 1Y8JA 2W14A 3EHYA 1IADA 1ZTQA 5LABA 4XBHA 1JANA 2X3CA 2POJA 3F17A 3LK8A 4ON1A 5I4OA 1QJJA 3KEJA 1ROSA 2CKIA 5CZMA 4L63A 3I7GA 5D3CA 4PKUA 1GKDA 1PWQA 4XM6A 4EFSA 1JJ9A 2PJTA 1UMTA 1KUHA 3O64A 4H82A 1B3DA 1CGFA 1FBLA 5BOTA 2OXWA 3TS4A 1O0QA 1A85A 4GF1A 3EDHA 1BQQM 2QPJA 1AKLA 4AIGA 1XFXA 3DPFA 3KECA 1HTDA 5L79A 1HY7A 3UVCA 4H49A 1GXDA 1I73A 1EAKA 4AXQA 3AYUA 3RTSA 1QICA 3DTKA 2EROA 1XFZA 1BSWA 3LEAA 2Y6CA 1WNIA 2WOAA 2OZRA 3P24A 3DPEA 3Q2HA 3I7IA 3Q2GA 1JAPA 2OY4A 4HX3A 1OM8A 1IAGA 2O3EA 1XFYA 2ERQA 3KWVC 3HYGA 1CXVA 3WV1A 4H76A 5BPAA 3HBVP 1ZXVA 4H30A 1PWWA 1BUDA 3ELMA 3TVCA 2X3AA 1BIWA 1ZXCA 4PKSA 3L0VA 3K7LA 2DW2A 1QIAA 3V96B 4XM7A 1SMPA 4AUOA 2W12A 4WK7A 1OMJA 3F18A 3LJTA 1CK7A 3KEKA 3HB2P 1QIBA 1FM1A 3DSLA 4GR3A 4GQLA 1C8TA 4WF6A 1A86A 5B5PA 1R54A 1OM6A 1JAQA 2N8RA 1GE7A 1D5JA 1D8FA 1CIZA 3LUNA 4L6TA 1AF0A 4L7AA 2E2DA 1Q3AA 3EDZA 1FLSA 2OW0A 5D2BA 1BZSA 1KUFA 2K9CA 1SRPA 1D8MA 830CA 4PKQA 3LQBA 3LE9A 3B92A 3AYKA 2A8HA 1QUAA 4A3WA 4G0DA 1JAOA 4GR8A 4H2EA 1XFWA 5I2ZA 2Y6DA 4A7BA 4H3XA 3KMEA 3OHOA 2K2GA 2YIGA 2OW9A 3KRYA 1R1JA 4H84A 4JIJA 4DV8A 4L19A 456CA 1KUGA 3AIGA 3EHXA 1J7NA 1KAPP 1D7XA 3F16A 2JIHA 2V4BA 5CXAA 1Y0VA 2X3BA 1UTZA 3O2XA 3VTGA 1G4KA 4PKTA 5D7WA 4ZR5A 1UEAA 1YQYA 4HMAA 3DTIA 3LKAA 4R3VA 3DWBA 2OVXA 4WKIA 1ZVXA 4JP4A 1H71P 3VI1A 4GR0A 3ZUKA 4IN9A 1KBCA 1SLMA 2KRJA 1BUVM 4PKWA 3GBOA 4FXYP 4DD8A 2J83A 2XS3A 3TSKA 2I47A 2JT6A 1DMTA 1PWPA 4GWMA 1C7KA 1R1HA 2OW2A 4FVLA 2JNPA 2RJPA 3KHIA 3LJZA 3WV2A 1ZP5A 2RJQA 5JMYA 1L6JA 1BM6A 4JA1A 2USNA 5CUHA 1PWUA 1OS9A 1G12A 1IACA 2JSDA 2AIGP 2OXZA 1USNA 1G05A 4JQGA 1JH1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HY7 A;  3G42 A;  3OHL A;  1GO8 P;  4PKV A;  2DW1 A;  2L0R A;  5B5O A;  4WKE A;  3N2U A;  4DF9 A;  4CTH A;  1ATL A;  1C3I A;  4AYK A;  4ILW D;  2WO9 A;  1DTH A;  1Y93 A;  2D1O A;  4DPE A;  1MNC A;  1XUC A;  2FV9 A;  2FV5 A;  1CGE A;  3TT4 A;  3B2Z A;  1QJI A;  2DDY A;  4H1Q A;  1CAQ A;  3SHI A;  1GE5 A;  1PWV A;  1ZS0 A;  2DW0 A;  5D1U A;  4IJO A;  3N2V A;  1YCM A;  3LIL A;  1GO7 P;  3LJG A;  2AYK A;  1YOU A;  1XUD A;  4XM8 A;  2D1N A;  1R55 A;  3WV3 A;  1SAT A;  1BKC E;  1RM8 A;  2W13 A;  3HDA P;  2MLS A;  3BA0 A;  4FXQ A;  3E8R A;  3ZVS A;  1IAA A;  2XS4 A;  1MMR A;  5I43 A;  1MMP A;  3F15 A;  1B8Y A;  2CLT A;  1GKC A;  1XFV A;  3F19 A;  1JK3 A;  1MMQ A;  2WO8 A;  4XCT A;  1MMB A;  1KUK A;  2YB9 A;  1GE6 A;  3CKI A;  1HV5 A;  1XFU A;  2O36 A;  3HDB A;  3HBU P;  1OS2 A;  2MLR A;  1R1I A;  2TCL A;  1SU3 A;  3G5C A;  3LGP A;  1BKC A;  1G9K A;  2HU6 A;  2Z2D A;  1RMZ A;  4Q1L A;  4FU4 A;  1JKY A;  1UMS A;  1HFS A;  1OM7 A;  5L7F A;  1Z3J A;  4QKZ A;  3NX7 A;  2ERP A;  3EWJ A;  2JT5 A;  2X7M A;  2MZH A;  5I0L A;  3ZXH A;  1AYK A;  5BOY A;  1HFC A;  2MZE A;  1CQR A;  1KUI A;  4G9L A;  1ND1 A;  3L0T A;  1K7G A;  3LMC A;  3U1R A;  4IUW A;  1BKC I;  5I12 A;  1K7I A;  2SRT A;  1EUB A;  3KMC A;  1IAB A;  1YP1 A;  3P1V A;  1EB6 A;  3LIK A;  3EDG A;  4GWN A;  1XUR A;  2J0T A;  1O0T A;  4WZV A;  4I35 A;  1HOV A;  3K7N A;  1AST A;  1I1I P;  3DNG A;  3EDI A;  3RTT A;  3DL1 A;  1OO9 A;  3B8Z A;  4JPA A;  4GUY A;  2OI0 A;  3LIR A;  2OW1 A;  1UTT A;  2W0D A;  1JIZ A;  3HY9 A;  2E3X A;  2W15 A;  1K7Q A;  3LQ0 A;  1BQO A;  1IAE A;  5D1S A;  4J4M A;  1G49 A;  3LUM A;  5I3M A;  3F1A A;  2OXU A;  4PKR A;  1I76 A;  5D1T A;  2MZI A;  1CGL A;  3MA2 A;  4I03 A;  5H8X A;  1JIW P;  2OVZ A;  3USN A;  1S4B P;  2DDF A;  966C A;  2OY2 A;  1SLN A;  1Y8J A;  2W14 A;  3EHY A;  1IAD A;  1ZTQ A;  5LAB A;  4XBH A;  1JAN A;  2X3C A;  2POJ A;  3F17 A;  3LK8 A;  4ON1 A;  5I4O A;  1QJJ A;  3KEJ A;  1ROS A;  2CKI A;  5CZM A;  4L63 A;  3I7G A;  5D3C A;  4PKU A;  1GKD A;  1PWQ A;  4XM6 A;  4EFS A;  1JJ9 A;  2PJT A;  1UMT A;  1KUH A;  3O64 A;  4H82 A;  1B3D A;  1CGF A;  1FBL A;  5BOT A;  2OXW A;  3TS4 A;  1O0Q A;  1A85 A;  4GF1 A;  3EDH A;  1BQQ M;  2QPJ A;  1AKL A;  4AIG A;  1XFX A;  3DPF A;  3KEC A;  1HTD A;  5L79 A;  1HY7 A;  3UVC A;  4H49 A;  1GXD A;  1I73 A;  1EAK A;  4AXQ A;  3AYU A;  3RTS A;  1QIC A;  2ERO A;  1XFZ A;  1BSW A;  3LEA A;  2Y6C A;  1WNI A;  2WOA A;  2OZR A;  3P24 A;  3DPE A;  3Q2H A;  3I7I A;  3Q2G A;  1JAP A;  2OY4 A;  4HX3 A;  1OM8 A;  1IAG A;  2O3E A;  1XFY A;  2ERQ A;  3KWV C;  3HYG A;  1CXV A;  3WV1 A;  4H76 A;  5BPA A;  3HBV P;  1ZXV A;  4H30 A;  1PWW A;  1BUD A;  3ELM A;  3TVC A;  2X3A A;  1BIW A;  1ZXC A;  4PKS A;  3L0V A;  3K7L A;  2DW2 A;  1QIA A;  3V96 B;  4XM7 A;  1SMP A;  4AUO A;  2W12 A;  4WK7 A;  1OMJ A;  3F18 A;  3LJT A;  1CK7 A;  3KEK A;  3HB2 P;  1QIB A;  1FM1 A;  3DSL A;  4GR3 A;  4GQL A;  1C8T A;  4WF6 A;  1A86 A;  5B5P A;  1R54 A;  1OM6 A;  1JAQ A;  2N8R A;  1GE7 A;  1D5J A;  1D8F A;  1CIZ A;  3LUN A;  4L6T A;  1AF0 A;  2E2D A;  1Q3A A;  3EDZ A;  1FLS A;  2OW0 A;  5D2B A;  1BZS A;  1KUF A;  2K9C A;  1SRP A;  1D8M A;  830C A;  4PKQ A;  3LQB A;  3LE9 A;  3B92 A;  3AYK A;  2A8H A;  1QUA A;  4A3W A;  4G0D A;  1JAO A;  4GR8 A;  4H2E A;  1XFW A;  5I2Z A;  2Y6D A;  4A7B A;  4H3X A;  3KME A;  3OHO A;  2K2G A;  2YIG A;  2OW9 A;  3KRY A;  1R1J A;  4H84 A;  4JIJ A;  4DV8 A;  4L19 A;  456C A;  1KUG A;  3AIG A;  3EHX A;  1J7N A;  1KAP P;  1D7X A;  3F16 A;  2JIH A;  2V4B A;  5CXA A;  1Y0V A;  2X3B A;  1UTZ A;  3O2X A;  3VTG A;  1G4K A;  4PKT A;  5D7W A;  4ZR5 A;  1UEA A;  1YQY A;  4HMA A;  3LKA A;  4R3V A;  3DWB A;  2OVX A;  4WKI A;  1ZVX A;  4JP4 A;  1H71 P;  3VI1 A;  4GR0 A;  3ZUK A;  4IN9 A;  1KBC A;  1SLM A;  2KRJ A;  1BUV M;  4PKW A;  3GBO A;  4FXY P;  4DD8 A;  2J83 A;  2XS3 A;  3TSK A;  2I47 A;  2JT6 A;  1DMT A;  1PWP A;  4GWM A;  1C7K A;  1R1H A;  2OW2 A;  4FVL A;  2JNP A;  2RJP A;  3KHI A;  3LJZ A;  3WV2 A;  1ZP5 A;  2RJQ A;  5JMY A;  1L6J A;  1BM6 A;  4JA1 A;  2USN A;  5CUH A;  1PWU A;  1OS9 A;  1G12 A;  1IAC A;  2JSD A;  2AIG P;  2OXZ A;  1USN A;  1G05 A;  4JQG A;  1JH1 A; 
#chains in the Genus database with same CATH topology
 3HY7 A;  3G42 A;  3OHL A;  1GO8 P;  4PKV A;  2DW1 A;  2L0R A;  5B5O A;  4WKE A;  3N2U A;  4DF9 A;  4CTH A;  1ATL A;  1C3I A;  4AYK A;  4ILW D;  2WO9 A;  1DTH A;  1Y93 A;  2D1O A;  4DPE A;  1MNC A;  1XUC A;  2FV9 A;  2FV5 A;  1CGE A;  3TT4 A;  3B2Z A;  1QJI A;  2DDY A;  4H1Q A;  1CAQ A;  3SHI A;  1GE5 A;  1PWV A;  1ZS0 A;  2DW0 A;  5D1U A;  4IJO A;  3N2V A;  1YCM A;  3LIL A;  1GO7 P;  3LJG A;  3DTE A;  2AYK A;  1YOU A;  1XUD A;  4XM8 A;  2D1N A;  1R55 A;  3WV3 A;  1SAT A;  1BKC E;  1RM8 A;  2W13 A;  3HDA P;  2MLS A;  3BA0 A;  4FXQ A;  3E8R A;  3ZVS A;  1IAA A;  2XS4 A;  1MMR A;  5I43 A;  1MMP A;  3F15 A;  1B8Y A;  2CLT A;  1GKC A;  1XFV A;  3F19 A;  1JK3 A;  1MMQ A;  2WO8 A;  4XCT A;  1MMB A;  1KUK A;  2YB9 A;  1GE6 A;  3CKI A;  1HV5 A;  1XFU A;  2O36 A;  3HDB A;  3HBU P;  1OS2 A;  2MLR A;  1R1I A;  2TCL A;  1SU3 A;  3G5C A;  3LGP A;  1BKC A;  1G9K A;  2HU6 A;  2Z2D A;  1RMZ A;  4Q1L A;  4FU4 A;  1JKY A;  1UMS A;  1HFS A;  1OM7 A;  5L7F A;  1Z3J A;  4QKZ A;  2YUF A;  3NX7 A;  1XAX A;  2ERP A;  3EWJ A;  2JT5 A;  2X7M A;  2MZH A;  5I0L A;  3ZXH A;  1AYK A;  5BOY A;  1HFC A;  2MZE A;  1CQR A;  1KUI A;  4G9L A;  1ND1 A;  3L0T A;  1K7G A;  3LMC A;  3U1R A;  4IUW A;  1BKC I;  5I12 A;  1K7I A;  2SRT A;  1EUB A;  3KMC A;  1IAB A;  1YP1 A;  3P1V A;  1EB6 A;  3LIK A;  3EDG A;  4GWN A;  1XUR A;  2J0T A;  1O0T A;  4WZV A;  4I35 A;  1HOV A;  3K7N A;  1AST A;  1I1I P;  3DNG A;  3EDI A;  3RTT A;  3DL1 A;  1OO9 A;  3B8Z A;  4JPA A;  4GUY A;  2OI0 A;  3LIR A;  2OW1 A;  1UTT A;  2W0D A;  1JIZ A;  3HY9 A;  2E3X A;  1OZ9 A;  2W15 A;  1K7Q A;  3LQ0 A;  1BQO A;  1IAE A;  5D1S A;  4J4M A;  1G49 A;  3LUM A;  5I3M A;  3F1A A;  2OXU A;  4PKR A;  1I76 A;  5D1T A;  2MZI A;  1CGL A;  3MA2 A;  4I03 A;  5H8X A;  1JIW P;  2OVZ A;  3USN A;  1S4B P;  2DDF A;  1XM5 A;  966C A;  2OY2 A;  1SLN A;  1Y8J A;  2W14 A;  3EHY A;  1IAD A;  1ZTQ A;  5LAB A;  4XBH A;  1JAN A;  2X3C A;  2POJ A;  3F17 A;  3LK8 A;  4ON1 A;  5I4O A;  1QJJ A;  3KEJ A;  1ROS A;  2CKI A;  5CZM A;  4L63 A;  3I7G A;  5D3C A;  4PKU A;  1GKD A;  1PWQ A;  4XM6 A;  4EFS A;  1JJ9 A;  2PJT A;  1UMT A;  1KUH A;  3O64 A;  4H82 A;  1B3D A;  1CGF A;  1FBL A;  5BOT A;  2OXW A;  3TS4 A;  1O0Q A;  1A85 A;  4GF1 A;  3EDH A;  1BQQ M;  2QPJ A;  1AKL A;  4AIG A;  1XFX A;  3DPF A;  3KEC A;  1HTD A;  5L79 A;  1HY7 A;  3UVC A;  4H49 A;  1GXD A;  1I73 A;  1EAK A;  4AXQ A;  3AYU A;  3RTS A;  1QIC A;  3DTK A;  2ERO A;  1XFZ A;  1BSW A;  3LEA A;  2Y6C A;  1WNI A;  2WOA A;  2OZR A;  3P24 A;  3DPE A;  3Q2H A;  3I7I A;  3Q2G A;  1JAP A;  2OY4 A;  4HX3 A;  1OM8 A;  1IAG A;  2O3E A;  1XFY A;  2ERQ A;  3KWV C;  3HYG A;  1CXV A;  3WV1 A;  4H76 A;  5BPA A;  3HBV P;  1ZXV A;  4H30 A;  1PWW A;  1BUD A;  3ELM A;  3TVC A;  2X3A A;  1BIW A;  1ZXC A;  4PKS A;  3L0V A;  3K7L A;  2DW2 A;  1QIA A;  3V96 B;  4XM7 A;  1SMP A;  4AUO A;  2W12 A;  4WK7 A;  1OMJ A;  3F18 A;  3LJT A;  1CK7 A;  3KEK A;  3HB2 P;  1QIB A;  1FM1 A;  3DSL A;  4GR3 A;  4GQL A;  1C8T A;  4WF6 A;  1A86 A;  5B5P A;  1R54 A;  1OM6 A;  1JAQ A;  2N8R A;  1GE7 A;  1D5J A;  1D8F A;  1CIZ A;  3LUN A;  4L6T A;  1AF0 A;  4L7A A;  2E2D A;  1Q3A A;  3EDZ A;  1FLS A;  2OW0 A;  5D2B A;  1BZS A;  1KUF A;  2K9C A;  1SRP A;  1D8M A;  830C A;  4PKQ A;  3LQB A;  3LE9 A;  3B92 A;  3AYK A;  2A8H A;  1QUA A;  4A3W A;  4G0D A;  1JAO A;  4GR8 A;  4H2E A;  1XFW A;  5I2Z A;  2Y6D A;  4A7B A;  4H3X A;  3KME A;  3OHO A;  2K2G A;  2YIG A;  2OW9 A;  3KRY A;  1R1J A;  4H84 A;  4JIJ A;  4DV8 A;  4L19 A;  456C A;  1KUG A;  3AIG A;  3EHX A;  1J7N A;  1KAP P;  1D7X A;  3F16 A;  2JIH A;  2V4B A;  5CXA A;  1Y0V A;  2X3B A;  1UTZ A;  3O2X A;  3VTG A;  1G4K A;  4PKT A;  5D7W A;  4ZR5 A;  1UEA A;  1YQY A;  4HMA A;  3DTI A;  3LKA A;  4R3V A;  3DWB A;  2OVX A;  4WKI A;  1ZVX A;  4JP4 A;  1H71 P;  3VI1 A;  4GR0 A;  3ZUK A;  4IN9 A;  1KBC A;  1SLM A;  2KRJ A;  1BUV M;  4PKW A;  3GBO A;  4FXY P;  4DD8 A;  2J83 A;  2XS3 A;  3TSK A;  2I47 A;  2JT6 A;  1DMT A;  1PWP A;  4GWM A;  1C7K A;  1R1H A;  2OW2 A;  4FVL A;  2JNP A;  2RJP A;  3KHI A;  3LJZ A;  3WV2 A;  1ZP5 A;  1TVI A;  2RJQ A;  5JMY A;  1L6J A;  1BM6 A;  4JA1 A;  2USN A;  5CUH A;  1PWU A;  1OS9 A;  1G12 A;  1IAC A;  2JSD A;  2AIG P;  2OXZ A;  1USN A;  1G05 A;  4JQG A;  1JH1 A; 
#chains in the Genus database with same CATH homology
 3HY7 A;  3G42 A;  3OHL A;  1GO8 P;  4PKV A;  2DW1 A;  2L0R A;  5B5O A;  4WKE A;  3N2U A;  4DF9 A;  4CTH A;  1ATL A;  1C3I A;  4AYK A;  4ILW D;  2WO9 A;  1DTH A;  1Y93 A;  2D1O A;  4DPE A;  1MNC A;  1XUC A;  2FV9 A;  2FV5 A;  1CGE A;  3TT4 A;  3B2Z A;  1QJI A;  2DDY A;  4H1Q A;  1CAQ A;  3SHI A;  1GE5 A;  1PWV A;  1ZS0 A;  2DW0 A;  5D1U A;  4IJO A;  3N2V A;  1YCM A;  3LIL A;  1GO7 P;  3LJG A;  3DTE A;  2AYK A;  1YOU A;  1XUD A;  4XM8 A;  2D1N A;  1R55 A;  3WV3 A;  1SAT A;  1BKC E;  1RM8 A;  2W13 A;  3HDA P;  2MLS A;  3BA0 A;  4FXQ A;  3E8R A;  3ZVS A;  1IAA A;  2XS4 A;  1MMR A;  5I43 A;  1MMP A;  3F15 A;  1B8Y A;  2CLT A;  1GKC A;  1XFV A;  3F19 A;  1JK3 A;  1MMQ A;  2WO8 A;  4XCT A;  1MMB A;  1KUK A;  2YB9 A;  1GE6 A;  3CKI A;  1HV5 A;  1XFU A;  2O36 A;  3HDB A;  3HBU P;  1OS2 A;  2MLR A;  1R1I A;  2TCL A;  1SU3 A;  3G5C A;  3LGP A;  1BKC A;  1G9K A;  2HU6 A;  2Z2D A;  1RMZ A;  4Q1L A;  4FU4 A;  1JKY A;  1UMS A;  1HFS A;  1OM7 A;  5L7F A;  1Z3J A;  4QKZ A;  2YUF A;  3NX7 A;  2ERP A;  3EWJ A;  2JT5 A;  2X7M A;  2MZH A;  5I0L A;  3ZXH A;  1AYK A;  5BOY A;  1HFC A;  2MZE A;  1CQR A;  1KUI A;  4G9L A;  1ND1 A;  3L0T A;  1K7G A;  3LMC A;  3U1R A;  4IUW A;  1BKC I;  5I12 A;  1K7I A;  2SRT A;  1EUB A;  3KMC A;  1IAB A;  1YP1 A;  3P1V A;  1EB6 A;  3LIK A;  3EDG A;  4GWN A;  1XUR A;  2J0T A;  1O0T A;  4WZV A;  4I35 A;  1HOV A;  3K7N A;  1AST A;  1I1I P;  3DNG A;  3EDI A;  3RTT A;  3DL1 A;  1OO9 A;  3B8Z A;  4JPA A;  4GUY A;  2OI0 A;  3LIR A;  2OW1 A;  1UTT A;  2W0D A;  1JIZ A;  3HY9 A;  2E3X A;  2W15 A;  1K7Q A;  3LQ0 A;  1BQO A;  1IAE A;  5D1S A;  4J4M A;  1G49 A;  3LUM A;  5I3M A;  3F1A A;  2OXU A;  4PKR A;  1I76 A;  5D1T A;  2MZI A;  1CGL A;  3MA2 A;  4I03 A;  5H8X A;  1JIW P;  2OVZ A;  3USN A;  1S4B P;  2DDF A;  966C A;  2OY2 A;  1SLN A;  1Y8J A;  2W14 A;  3EHY A;  1IAD A;  1ZTQ A;  5LAB A;  4XBH A;  1JAN A;  2X3C A;  2POJ A;  3F17 A;  3LK8 A;  4ON1 A;  5I4O A;  1QJJ A;  3KEJ A;  1ROS A;  2CKI A;  5CZM A;  4L63 A;  3I7G A;  5D3C A;  4PKU A;  1GKD A;  1PWQ A;  4XM6 A;  4EFS A;  1JJ9 A;  2PJT A;  1UMT A;  1KUH A;  3O64 A;  4H82 A;  1B3D A;  1CGF A;  1FBL A;  5BOT A;  2OXW A;  3TS4 A;  1O0Q A;  1A85 A;  4GF1 A;  3EDH A;  1BQQ M;  2QPJ A;  1AKL A;  4AIG A;  1XFX A;  3DPF A;  3KEC A;  1HTD A;  5L79 A;  1HY7 A;  3UVC A;  4H49 A;  1GXD A;  1I73 A;  1EAK A;  4AXQ A;  3AYU A;  3RTS A;  1QIC A;  3DTK A;  2ERO A;  1XFZ A;  1BSW A;  3LEA A;  2Y6C A;  1WNI A;  2WOA A;  2OZR A;  3P24 A;  3DPE A;  3Q2H A;  3I7I A;  3Q2G A;  1JAP A;  2OY4 A;  4HX3 A;  1OM8 A;  1IAG A;  2O3E A;  1XFY A;  2ERQ A;  3KWV C;  3HYG A;  1CXV A;  3WV1 A;  4H76 A;  5BPA A;  3HBV P;  1ZXV A;  4H30 A;  1PWW A;  1BUD A;  3ELM A;  3TVC A;  2X3A A;  1BIW A;  1ZXC A;  4PKS A;  3L0V A;  3K7L A;  2DW2 A;  1QIA A;  3V96 B;  4XM7 A;  1SMP A;  4AUO A;  2W12 A;  4WK7 A;  1OMJ A;  3F18 A;  3LJT A;  1CK7 A;  3KEK A;  3HB2 P;  1QIB A;  1FM1 A;  3DSL A;  4GR3 A;  4GQL A;  1C8T A;  4WF6 A;  1A86 A;  5B5P A;  1R54 A;  1OM6 A;  1JAQ A;  2N8R A;  1GE7 A;  1D5J A;  1D8F A;  1CIZ A;  3LUN A;  4L6T A;  1AF0 A;  4L7A A;  2E2D A;  1Q3A A;  3EDZ A;  1FLS A;  2OW0 A;  5D2B A;  1BZS A;  1KUF A;  2K9C A;  1SRP A;  1D8M A;  830C A;  4PKQ A;  3LQB A;  3LE9 A;  3B92 A;  3AYK A;  2A8H A;  1QUA A;  4A3W A;  4G0D A;  1JAO A;  4GR8 A;  4H2E A;  1XFW A;  5I2Z A;  2Y6D A;  4A7B A;  4H3X A;  3KME A;  3OHO A;  2K2G A;  2YIG A;  2OW9 A;  3KRY A;  1R1J A;  4H84 A;  4JIJ A;  4DV8 A;  4L19 A;  456C A;  1KUG A;  3AIG A;  3EHX A;  1J7N A;  1KAP P;  1D7X A;  3F16 A;  2JIH A;  2V4B A;  5CXA A;  1Y0V A;  2X3B A;  1UTZ A;  3O2X A;  3VTG A;  1G4K A;  4PKT A;  5D7W A;  4ZR5 A;  1UEA A;  1YQY A;  4HMA A;  3DTI A;  3LKA A;  4R3V A;  3DWB A;  2OVX A;  4WKI A;  1ZVX A;  4JP4 A;  1H71 P;  3VI1 A;  4GR0 A;  3ZUK A;  4IN9 A;  1KBC A;  1SLM A;  2KRJ A;  1BUV M;  4PKW A;  3GBO A;  4FXY P;  4DD8 A;  2J83 A;  2XS3 A;  3TSK A;  2I47 A;  2JT6 A;  1DMT A;  1PWP A;  4GWM A;  1C7K A;  1R1H A;  2OW2 A;  4FVL A;  2JNP A;  2RJP A;  3KHI A;  3LJZ A;  3WV2 A;  1ZP5 A;  2RJQ A;  5JMY A;  1L6J A;  1BM6 A;  4JA1 A;  2USN A;  5CUH A;  1PWU A;  1OS9 A;  1G12 A;  1IAC A;  2JSD A;  2AIG P;  2OXZ A;  1USN A;  1G05 A;  4JQG A;  1JH1 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...