3L0VA

Crystal structure of catalytic domain of tace with the first hydantoin inhibitor occupying the s1' pocket
Total Genus 83
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
83
sequence length
259
structure length
255
Chain Sequence
ADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYGGSPHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Discovery and SAR of hydantoin TACE inhibitors.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Disintegrin and metalloproteinase domain-containing protein
total genus 83
structure length 255
sequence length 259
chains with identical sequence B
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2009-12-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3l0vA00
1YP1A 1G05A 2JT6A 4ON1A 4JA1A 1XFYA 3F15A 1CGLA 4ILWD 1KUIA 3RTTA 1HY7A 1MNCA 830CA 5I43A 3BA0A 1D8FA 1BUVM 3P24A 4CTHA 2J83A 3CKIA 1ATLA 2WOAA 2Y6CA 1PWWA 1G4KA 4QKZA 2YB9A 1FLSA 4XM7A 4WKEA 1I1IP 1XFVA 2OXUA 4FXYP 1JAOA 1KUKA 3O2XA 3EHXA 4XCTA 1IABA 3HDAP 1AF0A 1MMQA 1AKLA 2OZRA 1BZSA 2MLRA 5D7WA 2YIGA 3EDZA 1XFZA 1UTZA 2RJPA 2W12A 1JIWP 1BIWA 3KHIA 2SRTA 3WV1A 1CIZA 1GE7A 1QJJA 3LMCA 5D3CA 1G9KA 3DPFA 1MMPA 3P1VA 2X3AA 2MZHA 3LE9A 1ZS0A 2WO9A 3AYUA 2MZEA 5CXAA 1O0QA 5BOYA 5LABA 3DPEA 1HOVA 1Y0VA 1IAGA 1K7IA 5I3MA 1KAPP 1JK3A 4H82A 2DDYA 2KRJA 2OI0A 1OM6A 3HB2P 2N8RA 4WK7A 5I12A 4AXQA 5D1SA 3K7LA 3KECA 2OW0A 1EAKA 1L6JA 4HMAA 3LKAA 2PJTA 4H1QA 4H3XA 1HFSA 3KMEA 3TSKA 1BUDA 1YOUA 2DDFA 1SMPA 1JAPA 1KUFA 2I47A 3TVCA 1S4BP 966CA 1KBCA 3LGPA 1IACA 1QUAA 1OM7A 1J7NA 1Z3JA 1RMZA 3HBVP 1BSWA 2OVZA 1G12A 1C8TA 1IAAA 1QIBA 1XFWA 3EDIA 1MMBA 1UEAA 5CZMA 3LQBA 456CA 4GR8A 3DWBA 3F17A 1CAQA 1PWQA 1R54A 3U1RA 5I2ZA 1CK7A 4GQLA 3I7IA 2ERQA 1C7KA 1HFCA 5CUHA 4H84A 1A86A 1ZTQA 3F19A 2RJQA 4WKIA 2ERPA 3E8RA 1I76A 4GWMA 4JPAA 1ZVXA 3HYGA 5JMYA 1UMTA 1BQOA 1CGFA 2OXWA 1BKCE 2OVXA 1B8YA 3I7GA 2E2DA 1AYKA 5L79A 5B5PA 1D5JA 1OS2A 4GR3A 1ND1A 1R1HA 3G5CA 3RTSA 4DV8A 3LILA 3F1AA 5BOTA 5L7FA 4HX3A 4XM6A 2K9CA 2XS4A 4PKSA 4H76A 4PKVA 3USNA 1JANA 1ROSA 1ZXVA 3OHOA 2DW0A 3EDHA 1I73A 3WV2A 2TCLA 1ASTA 3N2VA 3VTGA 3DSLA 4I35A 4PKUA 1R1IA 1CGEA 4GWNA 3F16A 4PKQA 1JH1A 3AIGA 1XURA 3LJTA 4L19A 1MMRA 2Z2DA 4L63A 2XS3A 2MLSA 1JIZA 2HU6A 1Y93A 2WO8A 3UVCA 3ZVSA 3B2ZA 2L0RA 2OY4A 2X7MA 2W0DA 4J4MA 1IADA 1YQYA 2K2GA 5B5OA 3G42A 1GE6A 3KRYA 1FM1A 2OW2A 5D2BA 4JIJA 2X3BA 4WF6A 2O3EA 1RM8A 3B92A 3F18A 2OXZA 3LIKA 1IAEA 4PKRA 3WV3A 4PKWA 1UMSA 4G9LA 4FXQA 4IJOA 1HV5A 1UTTA 1CQRA 3LJZA 1C3IA 3OHLA 2JT5A 2D1OA 2Y6DA 3DNGA 4XBHA 3L0VA 1OMJA 1GO8P 3Q2GA 5D1TA 4AUOA 4DPEA 3MA2A 4DD8A 4R3VA 1QICA 4GUYA 1XUCA 3LK8A 5I0LA 2OY2A 1R55A 3ZXHA 4A7BA 1JAQA 1PWUA 3HY7A 2EROA 1CXVA 1OS9A 1XFUA 3LIRA 2CLTA 4ZR5A 2DW1A 3LUMA 1BQQM 3HBUP 3EHYA 3KWVC 1SU3A 4I03A 4H2EA 1SATA 1QIAA 2POJA 1XUDA 3V96B 2J0TA 1QJIA 3LQ0A 3ELMA 4GR0A 1WNIA 1EB6A 2O36A 1GKCA 4IN9A 1GXDA 1G49A 3EDGA 1GO7P 2DW2A 1JJ9A 3KEKA 4Q1LA 2OW9A 4L6TA 1ZP5A 3LEAA 1A85A 3SHIA 3KMCA 1O0TA 2W14A 3N2UA 5D1UA 4H49A 1XFXA 3TS4A 3LJGA 1JKYA 1PWPA 2JSDA 3NX7A 2OW1A 4G0DA 1DMTA 1HTDA 2QPJA 2JNPA 1KUHA 3L0TA 2AIGP 5H8XA 1GE5A 1ZXCA 2W15A 4JP4A 2USNA 1BKCA 3O64A 4WZVA 2JIHA 4XM8A 4AYKA 4AIGA 3TT4A 1Y8JA 3GBOA 2A8HA 1SLNA 3DL1A 2E3XA 1Q3AA 3AYKA 1R1JA 3VI1A 1D8MA 1EUBA 1SLMA 3ZUKA 2FV9A 4GF1A 4PKTA 4DF9A 2FV5A 3LUNA 1K7QA 4A3WA 5I4OA 1PWVA 2W13A 2AYKA 1K7GA 1FBLA 1YCMA 3KEJA 1SRPA 2D1NA 2V4BA 4FVLA 4H30A 4EFSA 3HDBA 1H71P 1BM6A 2X3CA 1DTHA 3B8ZA 3Q2HA 5BPAA 1B3DA 4IUWA 1KUGA 3K7NA 1USNA 1GKDA 1BKCI 2CKIA 3HY9A 4JQGA 1OO9A 1D7XA 3EWJA 2MZIA 1OM8A 4FU4A
chains in the Genus database with same CATH superfamily
1YP1A 1G05A 2JT6A 4ON1A 4JA1A 1XFYA 3F15A 1CGLA 4ILWD 1KUIA 3RTTA 1HY7A 1MNCA 830CA 5I43A 3BA0A 1D8FA 1BUVM 3P24A 4CTHA 2J83A 3CKIA 1ATLA 2WOAA 2Y6CA 1PWWA 1G4KA 4QKZA 2YB9A 1FLSA 1XM5A 4XM7A 4WKEA 1I1IP 1XFVA 2OXUA 4FXYP 1JAOA 1KUKA 3O2XA 3EHXA 4XCTA 1IABA 3HDAP 1AF0A 1MMQA 1AKLA 2OZRA 1BZSA 2MLRA 5D7WA 2YIGA 3EDZA 1XFZA 1UTZA 2RJPA 2W12A 1JIWP 1BIWA 3KHIA 2SRTA 3WV1A 1CIZA 1GE7A 1QJJA 3LMCA 5D3CA 1G9KA 3DPFA 1MMPA 3P1VA 2X3AA 2MZHA 3LE9A 1ZS0A 2WO9A 3AYUA 2MZEA 5CXAA 1O0QA 5BOYA 5LABA 3DPEA 1HOVA 1Y0VA 1XAXA 1IAGA 1K7IA 5I3MA 1KAPP 1JK3A 4H82A 2DDYA 2KRJA 2OI0A 1OM6A 3HB2P 2N8RA 4WK7A 5I12A 4AXQA 5D1SA 3K7LA 3DTEA 3KECA 2OW0A 1EAKA 1L6JA 4HMAA 3LKAA 2PJTA 4H1QA 4H3XA 1HFSA 3KMEA 3TSKA 1BUDA 1YOUA 2DDFA 1SMPA 1JAPA 1KUFA 2I47A 3TVCA 1S4BP 966CA 1KBCA 3LGPA 1IACA 1QUAA 2YUFA 1OM7A 1J7NA 1TVIA 1Z3JA 1RMZA 3HBVP 1BSWA 2OVZA 1G12A 1C8TA 1IAAA 1QIBA 1XFWA 3EDIA 1MMBA 1UEAA 5CZMA 3LQBA 456CA 4GR8A 3DWBA 3F17A 1CAQA 1PWQA 1R54A 3U1RA 5I2ZA 1CK7A 4GQLA 3I7IA 2ERQA 1C7KA 1HFCA 5CUHA 4H84A 1A86A 1ZTQA 3F19A 2RJQA 4WKIA 2ERPA 3E8RA 1I76A 4GWMA 4JPAA 1ZVXA 3HYGA 5JMYA 1UMTA 1BQOA 1CGFA 2OXWA 1BKCE 2OVXA 1B8YA 3I7GA 2E2DA 1AYKA 5L79A 5B5PA 1D5JA 1OS2A 4GR3A 1ND1A 1R1HA 3G5CA 3RTSA 4DV8A 3LILA 3F1AA 5BOTA 5L7FA 4HX3A 4XM6A 2K9CA 2XS4A 4PKSA 4H76A 4PKVA 3USNA 1JANA 1ROSA 1ZXVA 3OHOA 2DW0A 3EDHA 1I73A 3WV2A 2TCLA 1ASTA 3N2VA 3VTGA 3DSLA 4I35A 4PKUA 1R1IA 3DTKA 1CGEA 4GWNA 3F16A 4PKQA 1JH1A 3AIGA 1XURA 3LJTA 4L19A 1MMRA 2Z2DA 4L63A 2XS3A 2MLSA 1JIZA 2HU6A 1Y93A 2WO8A 4L7AA 3UVCA 3ZVSA 3B2ZA 2L0RA 2OY4A 2X7MA 2W0DA 4J4MA 1IADA 1YQYA 2K2GA 5B5OA 3G42A 1GE6A 3KRYA 1FM1A 1OZ9A 2OW2A 5D2BA 4JIJA 2X3BA 4WF6A 2O3EA 1RM8A 3B92A 3F18A 2OXZA 3LIKA 1IAEA 4PKRA 3WV3A 4PKWA 1UMSA 4G9LA 4FXQA 4IJOA 1HV5A 1UTTA 1CQRA 3LJZA 1C3IA 3OHLA 2JT5A 2D1OA 2Y6DA 3DNGA 4XBHA 3L0VA 1OMJA 1GO8P 3Q2GA 5D1TA 4AUOA 4DPEA 3MA2A 4DD8A 4R3VA 1QICA 4GUYA 1XUCA 3LK8A 5I0LA 2OY2A 1R55A 3ZXHA 4A7BA 1JAQA 1PWUA 3HY7A 2EROA 1CXVA 1OS9A 1XFUA 3LIRA 2CLTA 4ZR5A 2DW1A 3LUMA 1BQQM 3HBUP 3EHYA 3KWVC 1SU3A 4I03A 4H2EA 1SATA 1QIAA 2POJA 1XUDA 3V96B 2J0TA 1QJIA 3LQ0A 3ELMA 4GR0A 1WNIA 1EB6A 2O36A 1GKCA 4IN9A 1GXDA 1G49A 3EDGA 1GO7P 2DW2A 1JJ9A 3KEKA 4Q1LA 2OW9A 4L6TA 1ZP5A 3LEAA 1A85A 3SHIA 3KMCA 1O0TA 2W14A 3N2UA 5D1UA 4H49A 1XFXA 3TS4A 3LJGA 1JKYA 1PWPA 2JSDA 3NX7A 2OW1A 4G0DA 1DMTA 1HTDA 2QPJA 2JNPA 1KUHA 3L0TA 2AIGP 5H8XA 1GE5A 1ZXCA 2W15A 4JP4A 2USNA 1BKCA 3O64A 4WZVA 2JIHA 4XM8A 4AYKA 4AIGA 3TT4A 1Y8JA 3GBOA 2A8HA 1SLNA 3DL1A 2E3XA 1Q3AA 3AYKA 1R1JA 3VI1A 1D8MA 1EUBA 1SLMA 3ZUKA 3DTIA 2FV9A 4GF1A 4PKTA 4DF9A 2FV5A 3LUNA 1K7QA 4A3WA 5I4OA 1PWVA 2W13A 2AYKA 1K7GA 1FBLA 1YCMA 3KEJA 1SRPA 2D1NA 2V4BA 4FVLA 4H30A 4EFSA 3HDBA 1H71P 1BM6A 2X3CA 1DTHA 3B8ZA 3Q2HA 5BPAA 1B3DA 4IUWA 1KUGA 3K7NA 1USNA 1GKDA 1BKCI 2CKIA 3HY9A 4JQGA 1OO9A 1D7XA 3EWJA 2MZIA 1OM8A 4FU4A
chains in the Genus database with same CATH topology
1YP1A 1G05A 2JT6A 4ON1A 4JA1A 1XFYA 3F15A 1CGLA 4ILWD 1KUIA 3RTTA 1HY7A 1MNCA 830CA 5I43A 3BA0A 1D8FA 1BUVM 3P24A 4CTHA 2J83A 3CKIA 1ATLA 2WOAA 2Y6CA 1PWWA 1G4KA 4QKZA 2YB9A 1FLSA 4XM7A 4WKEA 1I1IP 1XFVA 2OXUA 4FXYP 1JAOA 1KUKA 3O2XA 3EHXA 4XCTA 1IABA 3HDAP 1AF0A 1MMQA 1AKLA 2OZRA 1BZSA 2MLRA 5D7WA 2YIGA 3EDZA 1XFZA 1UTZA 2RJPA 2W12A 1JIWP 1BIWA 3KHIA 2SRTA 3WV1A 1CIZA 1GE7A 1QJJA 3LMCA 5D3CA 1G9KA 3DPFA 1MMPA 3P1VA 2X3AA 2MZHA 3LE9A 1ZS0A 2WO9A 3AYUA 2MZEA 5CXAA 1O0QA 5BOYA 5LABA 3DPEA 1HOVA 1Y0VA 1IAGA 1K7IA 5I3MA 1KAPP 1JK3A 4H82A 2DDYA 2KRJA 2OI0A 1OM6A 3HB2P 2N8RA 4WK7A 5I12A 4AXQA 5D1SA 3K7LA 3DTEA 3KECA 2OW0A 1EAKA 1L6JA 4HMAA 3LKAA 2PJTA 4H1QA 4H3XA 1HFSA 3KMEA 3TSKA 1BUDA 1YOUA 2DDFA 1SMPA 1JAPA 1KUFA 2I47A 3TVCA 1S4BP 966CA 1KBCA 3LGPA 1IACA 1QUAA 2YUFA 1OM7A 1J7NA 1Z3JA 1RMZA 3HBVP 1BSWA 2OVZA 1G12A 1C8TA 1IAAA 1QIBA 1XFWA 3EDIA 1MMBA 1UEAA 5CZMA 3LQBA 456CA 4GR8A 3DWBA 3F17A 1CAQA 1PWQA 1R54A 3U1RA 5I2ZA 1CK7A 4GQLA 3I7IA 2ERQA 1C7KA 1HFCA 5CUHA 4H84A 1A86A 1ZTQA 3F19A 2RJQA 4WKIA 2ERPA 3E8RA 1I76A 4GWMA 4JPAA 1ZVXA 3HYGA 5JMYA 1UMTA 1BQOA 1CGFA 2OXWA 1BKCE 2OVXA 1B8YA 3I7GA 2E2DA 1AYKA 5L79A 5B5PA 1D5JA 1OS2A 4GR3A 1ND1A 1R1HA 3G5CA 3RTSA 4DV8A 3LILA 3F1AA 5BOTA 5L7FA 4HX3A 4XM6A 2K9CA 2XS4A 4PKSA 4H76A 4PKVA 3USNA 1JANA 1ROSA 1ZXVA 3OHOA 2DW0A 3EDHA 1I73A 3WV2A 2TCLA 1ASTA 3N2VA 3VTGA 3DSLA 4I35A 4PKUA 1R1IA 3DTKA 1CGEA 4GWNA 3F16A 4PKQA 1JH1A 3AIGA 1XURA 3LJTA 4L19A 1MMRA 2Z2DA 4L63A 2XS3A 2MLSA 1JIZA 2HU6A 1Y93A 2WO8A 4L7AA 3UVCA 3ZVSA 3B2ZA 2L0RA 2OY4A 2X7MA 2W0DA 4J4MA 1IADA 1YQYA 2K2GA 5B5OA 3G42A 1GE6A 3KRYA 1FM1A 2OW2A 5D2BA 4JIJA 2X3BA 4WF6A 2O3EA 1RM8A 3B92A 3F18A 2OXZA 3LIKA 1IAEA 4PKRA 3WV3A 4PKWA 1UMSA 4G9LA 4FXQA 4IJOA 1HV5A 1UTTA 1CQRA 3LJZA 1C3IA 3OHLA 2JT5A 2D1OA 2Y6DA 3DNGA 4XBHA 3L0VA 1OMJA 1GO8P 3Q2GA 5D1TA 4AUOA 4DPEA 3MA2A 4DD8A 4R3VA 1QICA 4GUYA 1XUCA 3LK8A 5I0LA 2OY2A 1R55A 3ZXHA 4A7BA 1JAQA 1PWUA 3HY7A 2EROA 1CXVA 1OS9A 1XFUA 3LIRA 2CLTA 4ZR5A 2DW1A 3LUMA 1BQQM 3HBUP 3EHYA 3KWVC 1SU3A 4I03A 4H2EA 1SATA 1QIAA 2POJA 1XUDA 3V96B 2J0TA 1QJIA 3LQ0A 3ELMA 4GR0A 1WNIA 1EB6A 2O36A 1GKCA 4IN9A 1GXDA 1G49A 3EDGA 1GO7P 2DW2A 1JJ9A 3KEKA 4Q1LA 2OW9A 4L6TA 1ZP5A 3LEAA 1A85A 3SHIA 3KMCA 1O0TA 2W14A 3N2UA 5D1UA 4H49A 1XFXA 3TS4A 3LJGA 1JKYA 1PWPA 2JSDA 3NX7A 2OW1A 4G0DA 1DMTA 1HTDA 2QPJA 2JNPA 1KUHA 3L0TA 2AIGP 5H8XA 1GE5A 1ZXCA 2W15A 4JP4A 2USNA 1BKCA 3O64A 4WZVA 2JIHA 4XM8A 4AYKA 4AIGA 3TT4A 1Y8JA 3GBOA 2A8HA 1SLNA 3DL1A 2E3XA 1Q3AA 3AYKA 1R1JA 3VI1A 1D8MA 1EUBA 1SLMA 3ZUKA 3DTIA 2FV9A 4GF1A 4PKTA 4DF9A 2FV5A 3LUNA 1K7QA 4A3WA 5I4OA 1PWVA 2W13A 2AYKA 1K7GA 1FBLA 1YCMA 3KEJA 1SRPA 2D1NA 2V4BA 4FVLA 4H30A 4EFSA 3HDBA 1H71P 1BM6A 2X3CA 1DTHA 3B8ZA 3Q2HA 5BPAA 1B3DA 4IUWA 1KUGA 3K7NA 1USNA 1GKDA 1BKCI 2CKIA 3HY9A 4JQGA 1OO9A 1D7XA 3EWJA 2MZIA 1OM8A 4FU4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YP1 A;  1G05 A;  2JT6 A;  4ON1 A;  4JA1 A;  1XFY A;  3F15 A;  1CGL A;  4ILW D;  1KUI A;  3RTT A;  1HY7 A;  1MNC A;  830C A;  5I43 A;  3BA0 A;  1D8F A;  1BUV M;  3P24 A;  4CTH A;  2J83 A;  3CKI A;  1ATL A;  2WOA A;  2Y6C A;  1PWW A;  1G4K A;  4QKZ A;  2YB9 A;  1FLS A;  4XM7 A;  4WKE A;  1I1I P;  1XFV A;  2OXU A;  4FXY P;  1JAO A;  1KUK A;  3O2X A;  3EHX A;  4XCT A;  1IAB A;  3HDA P;  1AF0 A;  1MMQ A;  1AKL A;  2OZR A;  1BZS A;  2MLR A;  5D7W A;  2YIG A;  3EDZ A;  1XFZ A;  1UTZ A;  2RJP A;  2W12 A;  1JIW P;  1BIW A;  3KHI A;  2SRT A;  3WV1 A;  1CIZ A;  1GE7 A;  1QJJ A;  3LMC A;  5D3C A;  1G9K A;  3DPF A;  1MMP A;  3P1V A;  2X3A A;  2MZH A;  3LE9 A;  1ZS0 A;  2WO9 A;  3AYU A;  2MZE A;  5CXA A;  1O0Q A;  5BOY A;  5LAB A;  3DPE A;  1HOV A;  1Y0V A;  1IAG A;  1K7I A;  5I3M A;  1KAP P;  1JK3 A;  4H82 A;  2DDY A;  2KRJ A;  2OI0 A;  1OM6 A;  3HB2 P;  2N8R A;  4WK7 A;  5I12 A;  4AXQ A;  5D1S A;  3K7L A;  3KEC A;  2OW0 A;  1EAK A;  1L6J A;  4HMA A;  3LKA A;  2PJT A;  4H1Q A;  4H3X A;  1HFS A;  3KME A;  3TSK A;  1BUD A;  1YOU A;  2DDF A;  1SMP A;  1JAP A;  1KUF A;  2I47 A;  3TVC A;  1S4B P;  966C A;  1KBC A;  3LGP A;  1IAC A;  1QUA A;  1OM7 A;  1J7N A;  1Z3J A;  1RMZ A;  3HBV P;  1BSW A;  2OVZ A;  1G12 A;  1C8T A;  1IAA A;  1QIB A;  1XFW A;  3EDI A;  1MMB A;  1UEA A;  5CZM A;  3LQB A;  456C A;  4GR8 A;  3DWB A;  3F17 A;  1CAQ A;  1PWQ A;  1R54 A;  3U1R A;  5I2Z A;  1CK7 A;  4GQL A;  3I7I A;  2ERQ A;  1C7K A;  1HFC A;  5CUH A;  4H84 A;  1A86 A;  1ZTQ A;  3F19 A;  2RJQ A;  4WKI A;  2ERP A;  3E8R A;  1I76 A;  4GWM A;  4JPA A;  1ZVX A;  3HYG A;  5JMY A;  1UMT A;  1BQO A;  1CGF A;  2OXW A;  1BKC E;  2OVX A;  1B8Y A;  3I7G A;  2E2D A;  1AYK A;  5L79 A;  5B5P A;  1D5J A;  1OS2 A;  4GR3 A;  1ND1 A;  1R1H A;  3G5C A;  3RTS A;  4DV8 A;  3LIL A;  3F1A A;  5BOT A;  5L7F A;  4HX3 A;  4XM6 A;  2K9C A;  2XS4 A;  4PKS A;  4H76 A;  4PKV A;  3USN A;  1JAN A;  1ROS A;  1ZXV A;  3OHO A;  2DW0 A;  3EDH A;  1I73 A;  3WV2 A;  2TCL A;  1AST A;  3N2V A;  3VTG A;  3DSL A;  4I35 A;  4PKU A;  1R1I A;  1CGE A;  4GWN A;  3F16 A;  4PKQ A;  1JH1 A;  3AIG A;  1XUR A;  3LJT A;  4L19 A;  1MMR A;  2Z2D A;  4L63 A;  2XS3 A;  2MLS A;  1JIZ A;  2HU6 A;  1Y93 A;  2WO8 A;  3UVC A;  3ZVS A;  3B2Z A;  2L0R A;  2OY4 A;  2X7M A;  2W0D A;  4J4M A;  1IAD A;  1YQY A;  2K2G A;  5B5O A;  3G42 A;  1GE6 A;  3KRY A;  1FM1 A;  2OW2 A;  5D2B A;  4JIJ A;  2X3B A;  4WF6 A;  2O3E A;  1RM8 A;  3B92 A;  3F18 A;  2OXZ A;  3LIK A;  1IAE A;  4PKR A;  3WV3 A;  4PKW A;  1UMS A;  4G9L A;  4FXQ A;  4IJO A;  1HV5 A;  1UTT A;  1CQR A;  3LJZ A;  1C3I A;  3OHL A;  2JT5 A;  2D1O A;  2Y6D A;  3DNG A;  4XBH A;  3L0V A;  1OMJ A;  1GO8 P;  3Q2G A;  5D1T A;  4AUO A;  4DPE A;  3MA2 A;  4DD8 A;  4R3V A;  1QIC A;  4GUY A;  1XUC A;  3LK8 A;  5I0L A;  2OY2 A;  1R55 A;  3ZXH A;  4A7B A;  1JAQ A;  1PWU A;  3HY7 A;  2ERO A;  1CXV A;  1OS9 A;  1XFU A;  3LIR A;  2CLT A;  4ZR5 A;  2DW1 A;  3LUM A;  1BQQ M;  3HBU P;  3EHY A;  3KWV C;  1SU3 A;  4I03 A;  4H2E A;  1SAT A;  1QIA A;  2POJ A;  1XUD A;  3V96 B;  2J0T A;  1QJI A;  3LQ0 A;  3ELM A;  4GR0 A;  1WNI A;  1EB6 A;  2O36 A;  1GKC A;  4IN9 A;  1GXD A;  1G49 A;  3EDG A;  1GO7 P;  2DW2 A;  1JJ9 A;  3KEK A;  4Q1L A;  2OW9 A;  4L6T A;  1ZP5 A;  3LEA A;  1A85 A;  3SHI A;  3KMC A;  1O0T A;  2W14 A;  3N2U A;  5D1U A;  4H49 A;  1XFX A;  3TS4 A;  3LJG A;  1JKY A;  1PWP A;  2JSD A;  3NX7 A;  2OW1 A;  4G0D A;  1DMT A;  1HTD A;  2QPJ A;  2JNP A;  1KUH A;  3L0T A;  2AIG P;  5H8X A;  1GE5 A;  1ZXC A;  2W15 A;  4JP4 A;  2USN A;  1BKC A;  3O64 A;  4WZV A;  2JIH A;  4XM8 A;  4AYK A;  4AIG A;  3TT4 A;  1Y8J A;  3GBO A;  2A8H A;  1SLN A;  3DL1 A;  2E3X A;  1Q3A A;  3AYK A;  1R1J A;  3VI1 A;  1D8M A;  1EUB A;  1SLM A;  3ZUK A;  2FV9 A;  4GF1 A;  4PKT A;  4DF9 A;  2FV5 A;  3LUN A;  1K7Q A;  4A3W A;  5I4O A;  1PWV A;  2W13 A;  2AYK A;  1K7G A;  1FBL A;  1YCM A;  3KEJ A;  1SRP A;  2D1N A;  2V4B A;  4FVL A;  4H30 A;  4EFS A;  3HDB A;  1H71 P;  1BM6 A;  2X3C A;  1DTH A;  3B8Z A;  3Q2H A;  5BPA A;  1B3D A;  4IUW A;  1KUG A;  3K7N A;  1USN A;  1GKD A;  1BKC I;  2CKI A;  3HY9 A;  4JQG A;  1OO9 A;  1D7X A;  3EWJ A;  2MZI A;  1OM8 A;  4FU4 A; 
#chains in the Genus database with same CATH topology
 1YP1 A;  1G05 A;  2JT6 A;  4ON1 A;  4JA1 A;  1XFY A;  3F15 A;  1CGL A;  4ILW D;  1KUI A;  3RTT A;  1HY7 A;  1MNC A;  830C A;  5I43 A;  3BA0 A;  1D8F A;  1BUV M;  3P24 A;  4CTH A;  2J83 A;  3CKI A;  1ATL A;  2WOA A;  2Y6C A;  1PWW A;  1G4K A;  4QKZ A;  2YB9 A;  1FLS A;  1XM5 A;  4XM7 A;  4WKE A;  1I1I P;  1XFV A;  2OXU A;  4FXY P;  1JAO A;  1KUK A;  3O2X A;  3EHX A;  4XCT A;  1IAB A;  3HDA P;  1AF0 A;  1MMQ A;  1AKL A;  2OZR A;  1BZS A;  2MLR A;  5D7W A;  2YIG A;  3EDZ A;  1XFZ A;  1UTZ A;  2RJP A;  2W12 A;  1JIW P;  1BIW A;  3KHI A;  2SRT A;  3WV1 A;  1CIZ A;  1GE7 A;  1QJJ A;  3LMC A;  5D3C A;  1G9K A;  3DPF A;  1MMP A;  3P1V A;  2X3A A;  2MZH A;  3LE9 A;  1ZS0 A;  2WO9 A;  3AYU A;  2MZE A;  5CXA A;  1O0Q A;  5BOY A;  5LAB A;  3DPE A;  1HOV A;  1Y0V A;  1XAX A;  1IAG A;  1K7I A;  5I3M A;  1KAP P;  1JK3 A;  4H82 A;  2DDY A;  2KRJ A;  2OI0 A;  1OM6 A;  3HB2 P;  2N8R A;  4WK7 A;  5I12 A;  4AXQ A;  5D1S A;  3K7L A;  3DTE A;  3KEC A;  2OW0 A;  1EAK A;  1L6J A;  4HMA A;  3LKA A;  2PJT A;  4H1Q A;  4H3X A;  1HFS A;  3KME A;  3TSK A;  1BUD A;  1YOU A;  2DDF A;  1SMP A;  1JAP A;  1KUF A;  2I47 A;  3TVC A;  1S4B P;  966C A;  1KBC A;  3LGP A;  1IAC A;  1QUA A;  2YUF A;  1OM7 A;  1J7N A;  1TVI A;  1Z3J A;  1RMZ A;  3HBV P;  1BSW A;  2OVZ A;  1G12 A;  1C8T A;  1IAA A;  1QIB A;  1XFW A;  3EDI A;  1MMB A;  1UEA A;  5CZM A;  3LQB A;  456C A;  4GR8 A;  3DWB A;  3F17 A;  1CAQ A;  1PWQ A;  1R54 A;  3U1R A;  5I2Z A;  1CK7 A;  4GQL A;  3I7I A;  2ERQ A;  1C7K A;  1HFC A;  5CUH A;  4H84 A;  1A86 A;  1ZTQ A;  3F19 A;  2RJQ A;  4WKI A;  2ERP A;  3E8R A;  1I76 A;  4GWM A;  4JPA A;  1ZVX A;  3HYG A;  5JMY A;  1UMT A;  1BQO A;  1CGF A;  2OXW A;  1BKC E;  2OVX A;  1B8Y A;  3I7G A;  2E2D A;  1AYK A;  5L79 A;  5B5P A;  1D5J A;  1OS2 A;  4GR3 A;  1ND1 A;  1R1H A;  3G5C A;  3RTS A;  4DV8 A;  3LIL A;  3F1A A;  5BOT A;  5L7F A;  4HX3 A;  4XM6 A;  2K9C A;  2XS4 A;  4PKS A;  4H76 A;  4PKV A;  3USN A;  1JAN A;  1ROS A;  1ZXV A;  3OHO A;  2DW0 A;  3EDH A;  1I73 A;  3WV2 A;  2TCL A;  1AST A;  3N2V A;  3VTG A;  3DSL A;  4I35 A;  4PKU A;  1R1I A;  3DTK A;  1CGE A;  4GWN A;  3F16 A;  4PKQ A;  1JH1 A;  3AIG A;  1XUR A;  3LJT A;  4L19 A;  1MMR A;  2Z2D A;  4L63 A;  2XS3 A;  2MLS A;  1JIZ A;  2HU6 A;  1Y93 A;  2WO8 A;  4L7A A;  3UVC A;  3ZVS A;  3B2Z A;  2L0R A;  2OY4 A;  2X7M A;  2W0D A;  4J4M A;  1IAD A;  1YQY A;  2K2G A;  5B5O A;  3G42 A;  1GE6 A;  3KRY A;  1FM1 A;  1OZ9 A;  2OW2 A;  5D2B A;  4JIJ A;  2X3B A;  4WF6 A;  2O3E A;  1RM8 A;  3B92 A;  3F18 A;  2OXZ A;  3LIK A;  1IAE A;  4PKR A;  3WV3 A;  4PKW A;  1UMS A;  4G9L A;  4FXQ A;  4IJO A;  1HV5 A;  1UTT A;  1CQR A;  3LJZ A;  1C3I A;  3OHL A;  2JT5 A;  2D1O A;  2Y6D A;  3DNG A;  4XBH A;  3L0V A;  1OMJ A;  1GO8 P;  3Q2G A;  5D1T A;  4AUO A;  4DPE A;  3MA2 A;  4DD8 A;  4R3V A;  1QIC A;  4GUY A;  1XUC A;  3LK8 A;  5I0L A;  2OY2 A;  1R55 A;  3ZXH A;  4A7B A;  1JAQ A;  1PWU A;  3HY7 A;  2ERO A;  1CXV A;  1OS9 A;  1XFU A;  3LIR A;  2CLT A;  4ZR5 A;  2DW1 A;  3LUM A;  1BQQ M;  3HBU P;  3EHY A;  3KWV C;  1SU3 A;  4I03 A;  4H2E A;  1SAT A;  1QIA A;  2POJ A;  1XUD A;  3V96 B;  2J0T A;  1QJI A;  3LQ0 A;  3ELM A;  4GR0 A;  1WNI A;  1EB6 A;  2O36 A;  1GKC A;  4IN9 A;  1GXD A;  1G49 A;  3EDG A;  1GO7 P;  2DW2 A;  1JJ9 A;  3KEK A;  4Q1L A;  2OW9 A;  4L6T A;  1ZP5 A;  3LEA A;  1A85 A;  3SHI A;  3KMC A;  1O0T A;  2W14 A;  3N2U A;  5D1U A;  4H49 A;  1XFX A;  3TS4 A;  3LJG A;  1JKY A;  1PWP A;  2JSD A;  3NX7 A;  2OW1 A;  4G0D A;  1DMT A;  1HTD A;  2QPJ A;  2JNP A;  1KUH A;  3L0T A;  2AIG P;  5H8X A;  1GE5 A;  1ZXC A;  2W15 A;  4JP4 A;  2USN A;  1BKC A;  3O64 A;  4WZV A;  2JIH A;  4XM8 A;  4AYK A;  4AIG A;  3TT4 A;  1Y8J A;  3GBO A;  2A8H A;  1SLN A;  3DL1 A;  2E3X A;  1Q3A A;  3AYK A;  1R1J A;  3VI1 A;  1D8M A;  1EUB A;  1SLM A;  3ZUK A;  3DTI A;  2FV9 A;  4GF1 A;  4PKT A;  4DF9 A;  2FV5 A;  3LUN A;  1K7Q A;  4A3W A;  5I4O A;  1PWV A;  2W13 A;  2AYK A;  1K7G A;  1FBL A;  1YCM A;  3KEJ A;  1SRP A;  2D1N A;  2V4B A;  4FVL A;  4H30 A;  4EFS A;  3HDB A;  1H71 P;  1BM6 A;  2X3C A;  1DTH A;  3B8Z A;  3Q2H A;  5BPA A;  1B3D A;  4IUW A;  1KUG A;  3K7N A;  1USN A;  1GKD A;  1BKC I;  2CKI A;  3HY9 A;  4JQG A;  1OO9 A;  1D7X A;  3EWJ A;  2MZI A;  1OM8 A;  4FU4 A; 
#chains in the Genus database with same CATH homology
 1YP1 A;  1G05 A;  2JT6 A;  4ON1 A;  4JA1 A;  1XFY A;  3F15 A;  1CGL A;  4ILW D;  1KUI A;  3RTT A;  1HY7 A;  1MNC A;  830C A;  5I43 A;  3BA0 A;  1D8F A;  1BUV M;  3P24 A;  4CTH A;  2J83 A;  3CKI A;  1ATL A;  2WOA A;  2Y6C A;  1PWW A;  1G4K A;  4QKZ A;  2YB9 A;  1FLS A;  4XM7 A;  4WKE A;  1I1I P;  1XFV A;  2OXU A;  4FXY P;  1JAO A;  1KUK A;  3O2X A;  3EHX A;  4XCT A;  1IAB A;  3HDA P;  1AF0 A;  1MMQ A;  1AKL A;  2OZR A;  1BZS A;  2MLR A;  5D7W A;  2YIG A;  3EDZ A;  1XFZ A;  1UTZ A;  2RJP A;  2W12 A;  1JIW P;  1BIW A;  3KHI A;  2SRT A;  3WV1 A;  1CIZ A;  1GE7 A;  1QJJ A;  3LMC A;  5D3C A;  1G9K A;  3DPF A;  1MMP A;  3P1V A;  2X3A A;  2MZH A;  3LE9 A;  1ZS0 A;  2WO9 A;  3AYU A;  2MZE A;  5CXA A;  1O0Q A;  5BOY A;  5LAB A;  3DPE A;  1HOV A;  1Y0V A;  1IAG A;  1K7I A;  5I3M A;  1KAP P;  1JK3 A;  4H82 A;  2DDY A;  2KRJ A;  2OI0 A;  1OM6 A;  3HB2 P;  2N8R A;  4WK7 A;  5I12 A;  4AXQ A;  5D1S A;  3K7L A;  3DTE A;  3KEC A;  2OW0 A;  1EAK A;  1L6J A;  4HMA A;  3LKA A;  2PJT A;  4H1Q A;  4H3X A;  1HFS A;  3KME A;  3TSK A;  1BUD A;  1YOU A;  2DDF A;  1SMP A;  1JAP A;  1KUF A;  2I47 A;  3TVC A;  1S4B P;  966C A;  1KBC A;  3LGP A;  1IAC A;  1QUA A;  2YUF A;  1OM7 A;  1J7N A;  1Z3J A;  1RMZ A;  3HBV P;  1BSW A;  2OVZ A;  1G12 A;  1C8T A;  1IAA A;  1QIB A;  1XFW A;  3EDI A;  1MMB A;  1UEA A;  5CZM A;  3LQB A;  456C A;  4GR8 A;  3DWB A;  3F17 A;  1CAQ A;  1PWQ A;  1R54 A;  3U1R A;  5I2Z A;  1CK7 A;  4GQL A;  3I7I A;  2ERQ A;  1C7K A;  1HFC A;  5CUH A;  4H84 A;  1A86 A;  1ZTQ A;  3F19 A;  2RJQ A;  4WKI A;  2ERP A;  3E8R A;  1I76 A;  4GWM A;  4JPA A;  1ZVX A;  3HYG A;  5JMY A;  1UMT A;  1BQO A;  1CGF A;  2OXW A;  1BKC E;  2OVX A;  1B8Y A;  3I7G A;  2E2D A;  1AYK A;  5L79 A;  5B5P A;  1D5J A;  1OS2 A;  4GR3 A;  1ND1 A;  1R1H A;  3G5C A;  3RTS A;  4DV8 A;  3LIL A;  3F1A A;  5BOT A;  5L7F A;  4HX3 A;  4XM6 A;  2K9C A;  2XS4 A;  4PKS A;  4H76 A;  4PKV A;  3USN A;  1JAN A;  1ROS A;  1ZXV A;  3OHO A;  2DW0 A;  3EDH A;  1I73 A;  3WV2 A;  2TCL A;  1AST A;  3N2V A;  3VTG A;  3DSL A;  4I35 A;  4PKU A;  1R1I A;  3DTK A;  1CGE A;  4GWN A;  3F16 A;  4PKQ A;  1JH1 A;  3AIG A;  1XUR A;  3LJT A;  4L19 A;  1MMR A;  2Z2D A;  4L63 A;  2XS3 A;  2MLS A;  1JIZ A;  2HU6 A;  1Y93 A;  2WO8 A;  4L7A A;  3UVC A;  3ZVS A;  3B2Z A;  2L0R A;  2OY4 A;  2X7M A;  2W0D A;  4J4M A;  1IAD A;  1YQY A;  2K2G A;  5B5O A;  3G42 A;  1GE6 A;  3KRY A;  1FM1 A;  2OW2 A;  5D2B A;  4JIJ A;  2X3B A;  4WF6 A;  2O3E A;  1RM8 A;  3B92 A;  3F18 A;  2OXZ A;  3LIK A;  1IAE A;  4PKR A;  3WV3 A;  4PKW A;  1UMS A;  4G9L A;  4FXQ A;  4IJO A;  1HV5 A;  1UTT A;  1CQR A;  3LJZ A;  1C3I A;  3OHL A;  2JT5 A;  2D1O A;  2Y6D A;  3DNG A;  4XBH A;  3L0V A;  1OMJ A;  1GO8 P;  3Q2G A;  5D1T A;  4AUO A;  4DPE A;  3MA2 A;  4DD8 A;  4R3V A;  1QIC A;  4GUY A;  1XUC A;  3LK8 A;  5I0L A;  2OY2 A;  1R55 A;  3ZXH A;  4A7B A;  1JAQ A;  1PWU A;  3HY7 A;  2ERO A;  1CXV A;  1OS9 A;  1XFU A;  3LIR A;  2CLT A;  4ZR5 A;  2DW1 A;  3LUM A;  1BQQ M;  3HBU P;  3EHY A;  3KWV C;  1SU3 A;  4I03 A;  4H2E A;  1SAT A;  1QIA A;  2POJ A;  1XUD A;  3V96 B;  2J0T A;  1QJI A;  3LQ0 A;  3ELM A;  4GR0 A;  1WNI A;  1EB6 A;  2O36 A;  1GKC A;  4IN9 A;  1GXD A;  1G49 A;  3EDG A;  1GO7 P;  2DW2 A;  1JJ9 A;  3KEK A;  4Q1L A;  2OW9 A;  4L6T A;  1ZP5 A;  3LEA A;  1A85 A;  3SHI A;  3KMC A;  1O0T A;  2W14 A;  3N2U A;  5D1U A;  4H49 A;  1XFX A;  3TS4 A;  3LJG A;  1JKY A;  1PWP A;  2JSD A;  3NX7 A;  2OW1 A;  4G0D A;  1DMT A;  1HTD A;  2QPJ A;  2JNP A;  1KUH A;  3L0T A;  2AIG P;  5H8X A;  1GE5 A;  1ZXC A;  2W15 A;  4JP4 A;  2USN A;  1BKC A;  3O64 A;  4WZV A;  2JIH A;  4XM8 A;  4AYK A;  4AIG A;  3TT4 A;  1Y8J A;  3GBO A;  2A8H A;  1SLN A;  3DL1 A;  2E3X A;  1Q3A A;  3AYK A;  1R1J A;  3VI1 A;  1D8M A;  1EUB A;  1SLM A;  3ZUK A;  3DTI A;  2FV9 A;  4GF1 A;  4PKT A;  4DF9 A;  2FV5 A;  3LUN A;  1K7Q A;  4A3W A;  5I4O A;  1PWV A;  2W13 A;  2AYK A;  1K7G A;  1FBL A;  1YCM A;  3KEJ A;  1SRP A;  2D1N A;  2V4B A;  4FVL A;  4H30 A;  4EFS A;  3HDB A;  1H71 P;  1BM6 A;  2X3C A;  1DTH A;  3B8Z A;  3Q2H A;  5BPA A;  1B3D A;  4IUW A;  1KUG A;  3K7N A;  1USN A;  1GKD A;  1BKC I;  2CKI A;  3HY9 A;  4JQG A;  1OO9 A;  1D7X A;  3EWJ A;  2MZI A;  1OM8 A;  4FU4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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