3L0VA

Crystal structure of catalytic domain of tace with the first hydantoin inhibitor occupying the s1' pocket
Total Genus 83
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
83
sequence length
259
structure length
255
Chain Sequence
ADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYGGSPHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
publication title Discovery and SAR of hydantoin TACE inhibitors.
pubmed doi rcsb
molecule keywords Disintegrin and metalloproteinase domain-containing protein
total genus 83
structure length 255
sequence length 259
chains with identical sequence B
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2009-12-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3l0vA00
3HB2P 2O36A 2JIHA 2K2GA 3LJGA 2MLRA 3LIKA 1BIWA 1JIZA 1OM7A 2O3EA 4GR0A 1KAPP 1PWQA 3HBVP 1DTHA 4GQLA 5D1SA 2XS3A 2OXZA 1KUHA 3KMEA 2W13A 1J7NA 1SLMA 3HDBA 4H1QA 2W12A 4A7BA 1KUFA 2JSDA 4A3WA 3KRYA 456CA 1BKCI 3EHYA 3WV1A 4WZVA 2SRTA 3G42A 3OHOA 2DDYA 3RTTA 1IABA 1KUKA 3I7IA 5BOYA 2OVXA 5L79A 3LJTA 1EUBA 1OS2A 1PWPA 3B8ZA 1Q3AA 3BA0A 4JQGA 1HFSA 3O64A 3KMCA 3MA2A 2AYKA 2Y6DA 2JNPA 4H3XA 1MMPA 1QJIA 3LQ0A 2USNA 1CGLA 5CXAA 3LILA 1UMTA 1O0QA 4I03A 4DV8A 1BUDA 2V4BA 3EDIA 4PKTA 1QICA 3I7GA 4DPEA 2XS4A 3F19A 3DSLA 3KEJA 1XFVA 1D8MA 2W0DA 1G05A 2CKIA 3F18A 1FM1A 1D8FA 4Q1LA 4G0DA 1XFXA 3F1AA 2J83A 1A85A 4JP4A 2FV9A 1YQYA 1C3IA 3P24A 2OW1A 2D1OA 1R55A 1QUAA 1K7IA 2ERPA 3TT4A 3ZXHA 1C7KA 1SMPA 3DWBA 1IADA 5B5OA 966CA 1D7XA 5I12A 2YB9A 3LE9A 1DMTA 1KUIA 2OW0A 1BM6A 4ON1A 1A86A 2OW2A 2Y6CA 4H2EA 1JANA 3RTSA 5B5PA 4R3VA 4GR3A 1CQRA 5I43A 5JMYA 1CAQA 4GF1A 1OS9A 1YP1A 3DL1A 1PWWA 4FXYP 1BQQM 1G9KA 3TVCA 4WKIA 3F17A 1JK3A 5I4OA 1CGFA 1IAGA 1HOVA 4IJOA 3HYGA 4H30A 3DNGA 4AIGA 4ILWD 1EAKA 1XFWA 4XBHA 1C8TA 1XURA 1D5JA 2WO8A 3ELMA 3O2XA 1B8YA 1UTTA 4XM7A 1RM8A 3B92A 1GE7A 1R1JA 1GE6A 1XUDA 2L0RA 1PWUA 3ZUKA 2X7MA 4DD8A 1SU3A 1I76A 1R1HA 1K7GA 4PKWA 5BPAA 4FVLA 3VTGA 1QIAA 3LUNA 3SHIA 1YOUA 4CTHA 1UEAA 2OXUA 3EHXA 2TCLA 5D1UA 1I1IP 2MZHA 1YCMA 3LGPA 4H76A 3UVCA 1AYKA 1K7QA 2DW0A 3DPEA 3OHLA 3GBOA 2WOAA 3P1VA 1JJ9A 1FLSA 3N2VA 1HY7A 1JAPA 1ZS0A 1XFYA 1MNCA 3VI1A 3Q2GA 3WV2A 1ROSA 3CKIA 1ND1A 1R54A 2PJTA 4GUYA 5H8XA 3LJZA 3AYKA 5BOTA 2DW2A 3L0VA 3HY9A 4GR8A 1MMQA 5I0LA 2YIGA 3L0TA 4AXQA 1Z3JA 3LEAA 2E2DA 1UTZA 4DF9A 4H82A 1OM8A 1AKLA 1L6JA 1CK7A 3AIGA 3E8RA 4J4MA 3HDAP 4JPAA 1BZSA 2OY2A 4PKVA 2OZRA 2FV5A 1XFUA 2WO9A 3K7LA 3K7NA 1IAAA 1JAOA 1BQOA 1JAQA 2MZIA 4PKQA 4HX3A 3KHIA 4JIJA 1OO9A 1PWVA 1G4KA 1GXDA 2HU6A 2MLSA 4JA1A 1ATLA 2AIGP 2OXWA 4G9LA 1GKDA 4EFSA 1Y93A 2A8HA 1IAEA 5D3CA 1ZVXA 1QJJA 3WV3A 3KWVC 2OI0A 1RMZA 1HTDA 3EDHA 1FBLA 4PKUA 4QKZA 1G49A 3LQBA 3HY7A 2J0TA 1ASTA 3LIRA 5LABA 3LMCA 2Z2DA 2RJQA 1AF0A 4PKSA 3KEKA 4WKEA 2MZEA 3F16A 1JKYA 1XFZA 2OY4A 830CA 1G12A 1OM6A 1MMBA 1JIWP 2X3AA 4L63A 3NX7A 5I2ZA 2JT5A 2CLTA 2D1NA 1SLNA 2KRJA 1B3DA 2ERQA 4GWMA 4H84A 2W15A 4AUOA 3DPFA 1ZTQA 1XUCA 3EDZA 1UMSA 1O0TA 5D7WA 3HBUP 2RJPA 5CZMA 4IUWA 1I73A 1GE5A 1ZXCA 4IN9A 3TSKA 4AYKA 3EWJA 3V96B 2E3XA 4XM8A 5D1TA 4ZR5A 1HFCA 5I3MA 1R1IA 4FXQA 4FU4A 1BUVM 1SRPA 4I35A 4XM6A 2JT6A 2EROA 2W14A 2POJA 1H71P 4WK7A 5L7FA 2X3BA 1KUGA 3TS4A 1GKCA 4WF6A 1OMJA 5D2BA 2OW9A 2I47A 1Y0VA 4H49A 1EB6A 2DDFA 1BKCA 1BSWA 4HMAA 4GWNA 4PKRA 3USNA 3U1RA 1SATA 3ZVSA 1CIZA 2K9CA 2N8RA 1JH1A 3KECA 1BKCE 2QPJA 2DW1A 1MMRA 1HV5A 3AYUA 3G5CA 3B2ZA 1GO7P 1S4BP 1USNA 4L19A 1IACA 1ZXVA 1CGEA 1WNIA 3F15A 4L6TA 3Q2HA 2OVZA 1Y8JA 1GO8P 3LUMA 3EDGA 3LK8A 3LKAA 1ZP5A 1CXVA 1QIBA 1KBCA 5CUHA 4XCTA 2X3CA 3N2UA
chains in the Genus database with same CATH superfamily
3HB2P 2O36A 2JIHA 2K2GA 3LJGA 2MLRA 3LIKA 1BIWA 1JIZA 1OM7A 2O3EA 4GR0A 1KAPP 1PWQA 3HBVP 1DTHA 4GQLA 5D1SA 2XS3A 2OXZA 1KUHA 3KMEA 2W13A 1J7NA 1SLMA 3HDBA 4H1QA 2W12A 4A7BA 1KUFA 2JSDA 4A3WA 3KRYA 456CA 1BKCI 3EHYA 3WV1A 4WZVA 2SRTA 3G42A 3OHOA 2DDYA 3RTTA 1OZ9A 1IABA 1KUKA 3I7IA 5BOYA 2OVXA 3DTKA 5L79A 3LJTA 1EUBA 1OS2A 1PWPA 3B8ZA 1Q3AA 3BA0A 4JQGA 1HFSA 3O64A 3KMCA 3MA2A 2AYKA 2Y6DA 2JNPA 4H3XA 1MMPA 1QJIA 3LQ0A 2USNA 1CGLA 5CXAA 3LILA 1UMTA 1O0QA 4I03A 4DV8A 1BUDA 2V4BA 3EDIA 4PKTA 1QICA 3I7GA 4DPEA 2XS4A 3F19A 3DSLA 3KEJA 1XFVA 1D8MA 2W0DA 1G05A 2CKIA 3F18A 1FM1A 1D8FA 4Q1LA 4G0DA 1XFXA 3F1AA 2J83A 1A85A 4JP4A 2FV9A 1YQYA 1C3IA 3P24A 2OW1A 2D1OA 1R55A 1QUAA 1K7IA 2ERPA 3TT4A 3ZXHA 1C7KA 1SMPA 3DWBA 1IADA 5B5OA 966CA 1D7XA 5I12A 2YB9A 3LE9A 1DMTA 1KUIA 2OW0A 1BM6A 4ON1A 1A86A 2OW2A 2Y6CA 4H2EA 1JANA 3RTSA 5B5PA 4R3VA 4GR3A 1CQRA 5I43A 5JMYA 1CAQA 4GF1A 1OS9A 1YP1A 3DL1A 1PWWA 4FXYP 1BQQM 1G9KA 3TVCA 4WKIA 3F17A 1JK3A 5I4OA 1CGFA 1IAGA 1HOVA 4IJOA 3HYGA 4H30A 3DNGA 4AIGA 4ILWD 1EAKA 1XFWA 4XBHA 1C8TA 3DTIA 1XURA 1D5JA 2WO8A 3ELMA 3O2XA 1B8YA 1UTTA 4XM7A 1RM8A 3B92A 1GE7A 1R1JA 1GE6A 1XUDA 2L0RA 1PWUA 3ZUKA 2X7MA 4DD8A 1SU3A 1I76A 1R1HA 1K7GA 4PKWA 5BPAA 4FVLA 3VTGA 1QIAA 3LUNA 3SHIA 1YOUA 4CTHA 1UEAA 2OXUA 3EHXA 2TCLA 5D1UA 1I1IP 2MZHA 1YCMA 3LGPA 4H76A 3UVCA 1AYKA 1K7QA 2DW0A 3DPEA 1TVIA 3OHLA 3GBOA 2WOAA 3P1VA 1JJ9A 1FLSA 3N2VA 2YUFA 1HY7A 1JAPA 1ZS0A 1XFYA 1MNCA 3VI1A 3Q2GA 3WV2A 1ROSA 3CKIA 1ND1A 1R54A 2PJTA 4GUYA 5H8XA 3LJZA 3AYKA 5BOTA 2DW2A 3L0VA 3HY9A 4GR8A 1MMQA 5I0LA 2YIGA 3L0TA 4AXQA 1Z3JA 3LEAA 2E2DA 1UTZA 1XM5A 4DF9A 4H82A 1OM8A 1AKLA 1L6JA 1CK7A 3AIGA 3E8RA 4J4MA 3HDAP 4JPAA 1BZSA 2OY2A 4PKVA 2OZRA 2FV5A 1XFUA 2WO9A 3K7LA 3K7NA 1IAAA 1JAOA 1BQOA 1JAQA 2MZIA 4PKQA 4HX3A 3KHIA 4JIJA 1OO9A 1PWVA 1G4KA 1GXDA 1XAXA 2HU6A 2MLSA 4JA1A 1ATLA 2AIGP 2OXWA 4G9LA 1GKDA 4EFSA 1Y93A 2A8HA 1IAEA 5D3CA 1ZVXA 1QJJA 3WV3A 3KWVC 2OI0A 1RMZA 1HTDA 3EDHA 1FBLA 4PKUA 4QKZA 1G49A 3LQBA 3HY7A 2J0TA 1ASTA 3LIRA 5LABA 3LMCA 2Z2DA 2RJQA 1AF0A 4PKSA 3KEKA 4WKEA 2MZEA 3F16A 4L7AA 1JKYA 1XFZA 2OY4A 830CA 1G12A 1OM6A 1MMBA 1JIWP 2X3AA 4L63A 3NX7A 5I2ZA 2JT5A 2CLTA 2D1NA 1SLNA 2KRJA 1B3DA 2ERQA 4GWMA 4H84A 2W15A 4AUOA 3DPFA 1ZTQA 1XUCA 3EDZA 1UMSA 1O0TA 5D7WA 3HBUP 2RJPA 5CZMA 4IUWA 1I73A 1GE5A 1ZXCA 4IN9A 3TSKA 4AYKA 3EWJA 3V96B 2E3XA 4XM8A 5D1TA 4ZR5A 1HFCA 5I3MA 1R1IA 4FXQA 4FU4A 1BUVM 1SRPA 4I35A 4XM6A 2JT6A 2EROA 2W14A 2POJA 1H71P 3DTEA 4WK7A 5L7FA 2X3BA 1KUGA 3TS4A 1GKCA 4WF6A 1OMJA 5D2BA 2OW9A 2I47A 1Y0VA 4H49A 1EB6A 2DDFA 1BKCA 1BSWA 4HMAA 4GWNA 4PKRA 3USNA 3U1RA 1SATA 3ZVSA 1CIZA 2K9CA 2N8RA 1JH1A 3KECA 1BKCE 2QPJA 2DW1A 1MMRA 1HV5A 3AYUA 3G5CA 3B2ZA 1GO7P 1S4BP 1USNA 4L19A 1IACA 1ZXVA 1CGEA 1WNIA 3F15A 4L6TA 3Q2HA 2OVZA 1Y8JA 1GO8P 3LUMA 3EDGA 3LK8A 3LKAA 1ZP5A 1CXVA 1QIBA 1KBCA 5CUHA 4XCTA 2X3CA 3N2UA
chains in the Genus database with same CATH topology
3HB2P 2O36A 2JIHA 2K2GA 3LJGA 2MLRA 3LIKA 1BIWA 1JIZA 1OM7A 2O3EA 4GR0A 1KAPP 1PWQA 3HBVP 1DTHA 4GQLA 5D1SA 2XS3A 2OXZA 1KUHA 3KMEA 2W13A 1J7NA 1SLMA 3HDBA 4H1QA 2W12A 4A7BA 1KUFA 2JSDA 4A3WA 3KRYA 456CA 1BKCI 3EHYA 3WV1A 4WZVA 2SRTA 3G42A 3OHOA 2DDYA 3RTTA 1IABA 1KUKA 3I7IA 5BOYA 2OVXA 3DTKA 5L79A 3LJTA 1EUBA 1OS2A 1PWPA 3B8ZA 1Q3AA 3BA0A 4JQGA 1HFSA 3O64A 3KMCA 3MA2A 2AYKA 2Y6DA 2JNPA 4H3XA 1MMPA 1QJIA 3LQ0A 2USNA 1CGLA 5CXAA 3LILA 1UMTA 1O0QA 4I03A 4DV8A 1BUDA 2V4BA 3EDIA 4PKTA 1QICA 3I7GA 4DPEA 2XS4A 3F19A 3DSLA 3KEJA 1XFVA 1D8MA 2W0DA 1G05A 2CKIA 3F18A 1FM1A 1D8FA 4Q1LA 4G0DA 1XFXA 3F1AA 2J83A 1A85A 4JP4A 2FV9A 1YQYA 1C3IA 3P24A 2OW1A 2D1OA 1R55A 1QUAA 1K7IA 2ERPA 3TT4A 3ZXHA 1C7KA 1SMPA 3DWBA 1IADA 5B5OA 966CA 1D7XA 5I12A 2YB9A 3LE9A 1DMTA 1KUIA 2OW0A 1BM6A 4ON1A 1A86A 2OW2A 2Y6CA 4H2EA 1JANA 3RTSA 5B5PA 4R3VA 4GR3A 1CQRA 5I43A 5JMYA 1CAQA 4GF1A 1OS9A 1YP1A 3DL1A 1PWWA 4FXYP 1BQQM 1G9KA 3TVCA 4WKIA 3F17A 1JK3A 5I4OA 1CGFA 1IAGA 1HOVA 4IJOA 3HYGA 4H30A 3DNGA 4AIGA 4ILWD 1EAKA 1XFWA 4XBHA 1C8TA 3DTIA 1XURA 1D5JA 2WO8A 3ELMA 3O2XA 1B8YA 1UTTA 4XM7A 1RM8A 3B92A 1GE7A 1R1JA 1GE6A 1XUDA 2L0RA 1PWUA 3ZUKA 2X7MA 4DD8A 1SU3A 1I76A 1R1HA 1K7GA 4PKWA 5BPAA 4FVLA 3VTGA 1QIAA 3LUNA 3SHIA 1YOUA 4CTHA 1UEAA 2OXUA 3EHXA 2TCLA 5D1UA 1I1IP 2MZHA 1YCMA 3LGPA 4H76A 3UVCA 1AYKA 1K7QA 2DW0A 3DPEA 3OHLA 3GBOA 2WOAA 3P1VA 1JJ9A 1FLSA 3N2VA 2YUFA 1HY7A 1JAPA 1ZS0A 1XFYA 1MNCA 3VI1A 3Q2GA 3WV2A 1ROSA 3CKIA 1ND1A 1R54A 2PJTA 4GUYA 5H8XA 3LJZA 3AYKA 5BOTA 2DW2A 3L0VA 3HY9A 4GR8A 1MMQA 5I0LA 2YIGA 3L0TA 4AXQA 1Z3JA 3LEAA 2E2DA 1UTZA 4DF9A 4H82A 1OM8A 1AKLA 1L6JA 1CK7A 3AIGA 3E8RA 4J4MA 3HDAP 4JPAA 1BZSA 2OY2A 4PKVA 2OZRA 2FV5A 1XFUA 2WO9A 3K7LA 3K7NA 1IAAA 1JAOA 1BQOA 1JAQA 2MZIA 4PKQA 4HX3A 3KHIA 4JIJA 1OO9A 1PWVA 1G4KA 1GXDA 2HU6A 2MLSA 4JA1A 1ATLA 2AIGP 2OXWA 4G9LA 1GKDA 4EFSA 1Y93A 2A8HA 1IAEA 5D3CA 1ZVXA 1QJJA 3WV3A 3KWVC 2OI0A 1RMZA 1HTDA 3EDHA 1FBLA 4PKUA 4QKZA 1G49A 3LQBA 3HY7A 2J0TA 1ASTA 3LIRA 5LABA 3LMCA 2Z2DA 2RJQA 1AF0A 4PKSA 3KEKA 4WKEA 2MZEA 3F16A 4L7AA 1JKYA 1XFZA 2OY4A 830CA 1G12A 1OM6A 1MMBA 1JIWP 2X3AA 4L63A 3NX7A 5I2ZA 2JT5A 2CLTA 2D1NA 1SLNA 2KRJA 1B3DA 2ERQA 4GWMA 4H84A 2W15A 4AUOA 3DPFA 1ZTQA 1XUCA 3EDZA 1UMSA 1O0TA 5D7WA 3HBUP 2RJPA 5CZMA 4IUWA 1I73A 1GE5A 1ZXCA 4IN9A 3TSKA 4AYKA 3EWJA 3V96B 2E3XA 4XM8A 5D1TA 4ZR5A 1HFCA 5I3MA 1R1IA 4FXQA 4FU4A 1BUVM 1SRPA 4I35A 4XM6A 2JT6A 2EROA 2W14A 2POJA 1H71P 3DTEA 4WK7A 5L7FA 2X3BA 1KUGA 3TS4A 1GKCA 4WF6A 1OMJA 5D2BA 2OW9A 2I47A 1Y0VA 4H49A 1EB6A 2DDFA 1BKCA 1BSWA 4HMAA 4GWNA 4PKRA 3USNA 3U1RA 1SATA 3ZVSA 1CIZA 2K9CA 2N8RA 1JH1A 3KECA 1BKCE 2QPJA 2DW1A 1MMRA 1HV5A 3AYUA 3G5CA 3B2ZA 1GO7P 1S4BP 1USNA 4L19A 1IACA 1ZXVA 1CGEA 1WNIA 3F15A 4L6TA 3Q2HA 2OVZA 1Y8JA 1GO8P 3LUMA 3EDGA 3LK8A 3LKAA 1ZP5A 1CXVA 1QIBA 1KBCA 5CUHA 4XCTA 2X3CA 3N2UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HB2 P;  2O36 A;  2JIH A;  2K2G A;  3LJG A;  2MLR A;  3LIK A;  1BIW A;  1JIZ A;  1OM7 A;  2O3E A;  4GR0 A;  1KAP P;  1PWQ A;  3HBV P;  1DTH A;  4GQL A;  5D1S A;  2XS3 A;  2OXZ A;  1KUH A;  3KME A;  2W13 A;  1J7N A;  1SLM A;  3HDB A;  4H1Q A;  2W12 A;  4A7B A;  1KUF A;  2JSD A;  4A3W A;  3KRY A;  456C A;  1BKC I;  3EHY A;  3WV1 A;  4WZV A;  2SRT A;  3G42 A;  3OHO A;  2DDY A;  3RTT A;  1IAB A;  1KUK A;  3I7I A;  5BOY A;  2OVX A;  5L79 A;  3LJT A;  1EUB A;  1OS2 A;  1PWP A;  3B8Z A;  1Q3A A;  3BA0 A;  4JQG A;  1HFS A;  3O64 A;  3KMC A;  3MA2 A;  2AYK A;  2Y6D A;  2JNP A;  4H3X A;  1MMP A;  1QJI A;  3LQ0 A;  2USN A;  1CGL A;  5CXA A;  3LIL A;  1UMT A;  1O0Q A;  4I03 A;  4DV8 A;  1BUD A;  2V4B A;  3EDI A;  4PKT A;  1QIC A;  3I7G A;  4DPE A;  2XS4 A;  3F19 A;  3DSL A;  3KEJ A;  1XFV A;  1D8M A;  2W0D A;  1G05 A;  2CKI A;  3F18 A;  1FM1 A;  1D8F A;  4Q1L A;  4G0D A;  1XFX A;  3F1A A;  2J83 A;  1A85 A;  4JP4 A;  2FV9 A;  1YQY A;  1C3I A;  3P24 A;  2OW1 A;  2D1O A;  1R55 A;  1QUA A;  1K7I A;  2ERP A;  3TT4 A;  3ZXH A;  1C7K A;  1SMP A;  3DWB A;  1IAD A;  5B5O A;  966C A;  1D7X A;  5I12 A;  2YB9 A;  3LE9 A;  1DMT A;  1KUI A;  2OW0 A;  1BM6 A;  4ON1 A;  1A86 A;  2OW2 A;  2Y6C A;  4H2E A;  1JAN A;  3RTS A;  5B5P A;  4R3V A;  4GR3 A;  1CQR A;  5I43 A;  5JMY A;  1CAQ A;  4GF1 A;  1OS9 A;  1YP1 A;  3DL1 A;  1PWW A;  4FXY P;  1BQQ M;  1G9K A;  3TVC A;  4WKI A;  3F17 A;  1JK3 A;  5I4O A;  1CGF A;  1IAG A;  1HOV A;  4IJO A;  3HYG A;  4H30 A;  3DNG A;  4AIG A;  4ILW D;  1EAK A;  1XFW A;  4XBH A;  1C8T A;  1XUR A;  1D5J A;  2WO8 A;  3ELM A;  3O2X A;  1B8Y A;  1UTT A;  4XM7 A;  1RM8 A;  3B92 A;  1GE7 A;  1R1J A;  1GE6 A;  1XUD A;  2L0R A;  1PWU A;  3ZUK A;  2X7M A;  4DD8 A;  1SU3 A;  1I76 A;  1R1H A;  1K7G A;  4PKW A;  5BPA A;  4FVL A;  3VTG A;  1QIA A;  3LUN A;  3SHI A;  1YOU A;  4CTH A;  1UEA A;  2OXU A;  3EHX A;  2TCL A;  5D1U A;  1I1I P;  2MZH A;  1YCM A;  3LGP A;  4H76 A;  3UVC A;  1AYK A;  1K7Q A;  2DW0 A;  3DPE A;  3OHL A;  3GBO A;  2WOA A;  3P1V A;  1JJ9 A;  1FLS A;  3N2V A;  1HY7 A;  1JAP A;  1ZS0 A;  1XFY A;  1MNC A;  3VI1 A;  3Q2G A;  3WV2 A;  1ROS A;  3CKI A;  1ND1 A;  1R54 A;  2PJT A;  4GUY A;  5H8X A;  3LJZ A;  3AYK A;  5BOT A;  2DW2 A;  3L0V A;  3HY9 A;  4GR8 A;  1MMQ A;  5I0L A;  2YIG A;  3L0T A;  4AXQ A;  1Z3J A;  3LEA A;  2E2D A;  1UTZ A;  4DF9 A;  4H82 A;  1OM8 A;  1AKL A;  1L6J A;  1CK7 A;  3AIG A;  3E8R A;  4J4M A;  3HDA P;  4JPA A;  1BZS A;  2OY2 A;  4PKV A;  2OZR A;  2FV5 A;  1XFU A;  2WO9 A;  3K7L A;  3K7N A;  1IAA A;  1JAO A;  1BQO A;  1JAQ A;  2MZI A;  4PKQ A;  4HX3 A;  3KHI A;  4JIJ A;  1OO9 A;  1PWV A;  1G4K A;  1GXD A;  2HU6 A;  2MLS A;  4JA1 A;  1ATL A;  2AIG P;  2OXW A;  4G9L A;  1GKD A;  4EFS A;  1Y93 A;  2A8H A;  1IAE A;  5D3C A;  1ZVX A;  1QJJ A;  3WV3 A;  3KWV C;  2OI0 A;  1RMZ A;  1HTD A;  3EDH A;  1FBL A;  4PKU A;  4QKZ A;  1G49 A;  3LQB A;  3HY7 A;  2J0T A;  1AST A;  3LIR A;  5LAB A;  3LMC A;  2Z2D A;  2RJQ A;  1AF0 A;  4PKS A;  3KEK A;  4WKE A;  2MZE A;  3F16 A;  1JKY A;  1XFZ A;  2OY4 A;  830C A;  1G12 A;  1OM6 A;  1MMB A;  1JIW P;  2X3A A;  4L63 A;  3NX7 A;  5I2Z A;  2JT5 A;  2CLT A;  2D1N A;  1SLN A;  2KRJ A;  1B3D A;  2ERQ A;  4GWM A;  4H84 A;  2W15 A;  4AUO A;  3DPF A;  1ZTQ A;  1XUC A;  3EDZ A;  1UMS A;  1O0T A;  5D7W A;  3HBU P;  2RJP A;  5CZM A;  4IUW A;  1I73 A;  1GE5 A;  1ZXC A;  4IN9 A;  3TSK A;  4AYK A;  3EWJ A;  3V96 B;  2E3X A;  4XM8 A;  5D1T A;  4ZR5 A;  1HFC A;  5I3M A;  1R1I A;  4FXQ A;  4FU4 A;  1BUV M;  1SRP A;  4I35 A;  4XM6 A;  2JT6 A;  2ERO A;  2W14 A;  2POJ A;  1H71 P;  4WK7 A;  5L7F A;  2X3B A;  1KUG A;  3TS4 A;  1GKC A;  4WF6 A;  1OMJ A;  5D2B A;  2OW9 A;  2I47 A;  1Y0V A;  4H49 A;  1EB6 A;  2DDF A;  1BKC A;  1BSW A;  4HMA A;  4GWN A;  4PKR A;  3USN A;  3U1R A;  1SAT A;  3ZVS A;  1CIZ A;  2K9C A;  2N8R A;  1JH1 A;  3KEC A;  1BKC E;  2QPJ A;  2DW1 A;  1MMR A;  1HV5 A;  3AYU A;  3G5C A;  3B2Z A;  1GO7 P;  1S4B P;  1USN A;  4L19 A;  1IAC A;  1ZXV A;  1CGE A;  1WNI A;  3F15 A;  4L6T A;  3Q2H A;  2OVZ A;  1Y8J A;  1GO8 P;  3LUM A;  3EDG A;  3LK8 A;  3LKA A;  1ZP5 A;  1CXV A;  1QIB A;  1KBC A;  5CUH A;  4XCT A;  2X3C A;  3N2U A; 
#chains in the Genus database with same CATH topology
 3HB2 P;  2O36 A;  2JIH A;  2K2G A;  3LJG A;  2MLR A;  3LIK A;  1BIW A;  1JIZ A;  1OM7 A;  2O3E A;  4GR0 A;  1KAP P;  1PWQ A;  3HBV P;  1DTH A;  4GQL A;  5D1S A;  2XS3 A;  2OXZ A;  1KUH A;  3KME A;  2W13 A;  1J7N A;  1SLM A;  3HDB A;  4H1Q A;  2W12 A;  4A7B A;  1KUF A;  2JSD A;  4A3W A;  3KRY A;  456C A;  1BKC I;  3EHY A;  3WV1 A;  4WZV A;  2SRT A;  3G42 A;  3OHO A;  2DDY A;  3RTT A;  1OZ9 A;  1IAB A;  1KUK A;  3I7I A;  5BOY A;  2OVX A;  3DTK A;  5L79 A;  3LJT A;  1EUB A;  1OS2 A;  1PWP A;  3B8Z A;  1Q3A A;  3BA0 A;  4JQG A;  1HFS A;  3O64 A;  3KMC A;  3MA2 A;  2AYK A;  2Y6D A;  2JNP A;  4H3X A;  1MMP A;  1QJI A;  3LQ0 A;  2USN A;  1CGL A;  5CXA A;  3LIL A;  1UMT A;  1O0Q A;  4I03 A;  4DV8 A;  1BUD A;  2V4B A;  3EDI A;  4PKT A;  1QIC A;  3I7G A;  4DPE A;  2XS4 A;  3F19 A;  3DSL A;  3KEJ A;  1XFV A;  1D8M A;  2W0D A;  1G05 A;  2CKI A;  3F18 A;  1FM1 A;  1D8F A;  4Q1L A;  4G0D A;  1XFX A;  3F1A A;  2J83 A;  1A85 A;  4JP4 A;  2FV9 A;  1YQY A;  1C3I A;  3P24 A;  2OW1 A;  2D1O A;  1R55 A;  1QUA A;  1K7I A;  2ERP A;  3TT4 A;  3ZXH A;  1C7K A;  1SMP A;  3DWB A;  1IAD A;  5B5O A;  966C A;  1D7X A;  5I12 A;  2YB9 A;  3LE9 A;  1DMT A;  1KUI A;  2OW0 A;  1BM6 A;  4ON1 A;  1A86 A;  2OW2 A;  2Y6C A;  4H2E A;  1JAN A;  3RTS A;  5B5P A;  4R3V A;  4GR3 A;  1CQR A;  5I43 A;  5JMY A;  1CAQ A;  4GF1 A;  1OS9 A;  1YP1 A;  3DL1 A;  1PWW A;  4FXY P;  1BQQ M;  1G9K A;  3TVC A;  4WKI A;  3F17 A;  1JK3 A;  5I4O A;  1CGF A;  1IAG A;  1HOV A;  4IJO A;  3HYG A;  4H30 A;  3DNG A;  4AIG A;  4ILW D;  1EAK A;  1XFW A;  4XBH A;  1C8T A;  3DTI A;  1XUR A;  1D5J A;  2WO8 A;  3ELM A;  3O2X A;  1B8Y A;  1UTT A;  4XM7 A;  1RM8 A;  3B92 A;  1GE7 A;  1R1J A;  1GE6 A;  1XUD A;  2L0R A;  1PWU A;  3ZUK A;  2X7M A;  4DD8 A;  1SU3 A;  1I76 A;  1R1H A;  1K7G A;  4PKW A;  5BPA A;  4FVL A;  3VTG A;  1QIA A;  3LUN A;  3SHI A;  1YOU A;  4CTH A;  1UEA A;  2OXU A;  3EHX A;  2TCL A;  5D1U A;  1I1I P;  2MZH A;  1YCM A;  3LGP A;  4H76 A;  3UVC A;  1AYK A;  1K7Q A;  2DW0 A;  3DPE A;  1TVI A;  3OHL A;  3GBO A;  2WOA A;  3P1V A;  1JJ9 A;  1FLS A;  3N2V A;  2YUF A;  1HY7 A;  1JAP A;  1ZS0 A;  1XFY A;  1MNC A;  3VI1 A;  3Q2G A;  3WV2 A;  1ROS A;  3CKI A;  1ND1 A;  1R54 A;  2PJT A;  4GUY A;  5H8X A;  3LJZ A;  3AYK A;  5BOT A;  2DW2 A;  3L0V A;  3HY9 A;  4GR8 A;  1MMQ A;  5I0L A;  2YIG A;  3L0T A;  4AXQ A;  1Z3J A;  3LEA A;  2E2D A;  1UTZ A;  1XM5 A;  4DF9 A;  4H82 A;  1OM8 A;  1AKL A;  1L6J A;  1CK7 A;  3AIG A;  3E8R A;  4J4M A;  3HDA P;  4JPA A;  1BZS A;  2OY2 A;  4PKV A;  2OZR A;  2FV5 A;  1XFU A;  2WO9 A;  3K7L A;  3K7N A;  1IAA A;  1JAO A;  1BQO A;  1JAQ A;  2MZI A;  4PKQ A;  4HX3 A;  3KHI A;  4JIJ A;  1OO9 A;  1PWV A;  1G4K A;  1GXD A;  1XAX A;  2HU6 A;  2MLS A;  4JA1 A;  1ATL A;  2AIG P;  2OXW A;  4G9L A;  1GKD A;  4EFS A;  1Y93 A;  2A8H A;  1IAE A;  5D3C A;  1ZVX A;  1QJJ A;  3WV3 A;  3KWV C;  2OI0 A;  1RMZ A;  1HTD A;  3EDH A;  1FBL A;  4PKU A;  4QKZ A;  1G49 A;  3LQB A;  3HY7 A;  2J0T A;  1AST A;  3LIR A;  5LAB A;  3LMC A;  2Z2D A;  2RJQ A;  1AF0 A;  4PKS A;  3KEK A;  4WKE A;  2MZE A;  3F16 A;  4L7A A;  1JKY A;  1XFZ A;  2OY4 A;  830C A;  1G12 A;  1OM6 A;  1MMB A;  1JIW P;  2X3A A;  4L63 A;  3NX7 A;  5I2Z A;  2JT5 A;  2CLT A;  2D1N A;  1SLN A;  2KRJ A;  1B3D A;  2ERQ A;  4GWM A;  4H84 A;  2W15 A;  4AUO A;  3DPF A;  1ZTQ A;  1XUC A;  3EDZ A;  1UMS A;  1O0T A;  5D7W A;  3HBU P;  2RJP A;  5CZM A;  4IUW A;  1I73 A;  1GE5 A;  1ZXC A;  4IN9 A;  3TSK A;  4AYK A;  3EWJ A;  3V96 B;  2E3X A;  4XM8 A;  5D1T A;  4ZR5 A;  1HFC A;  5I3M A;  1R1I A;  4FXQ A;  4FU4 A;  1BUV M;  1SRP A;  4I35 A;  4XM6 A;  2JT6 A;  2ERO A;  2W14 A;  2POJ A;  1H71 P;  3DTE A;  4WK7 A;  5L7F A;  2X3B A;  1KUG A;  3TS4 A;  1GKC A;  4WF6 A;  1OMJ A;  5D2B A;  2OW9 A;  2I47 A;  1Y0V A;  4H49 A;  1EB6 A;  2DDF A;  1BKC A;  1BSW A;  4HMA A;  4GWN A;  4PKR A;  3USN A;  3U1R A;  1SAT A;  3ZVS A;  1CIZ A;  2K9C A;  2N8R A;  1JH1 A;  3KEC A;  1BKC E;  2QPJ A;  2DW1 A;  1MMR A;  1HV5 A;  3AYU A;  3G5C A;  3B2Z A;  1GO7 P;  1S4B P;  1USN A;  4L19 A;  1IAC A;  1ZXV A;  1CGE A;  1WNI A;  3F15 A;  4L6T A;  3Q2H A;  2OVZ A;  1Y8J A;  1GO8 P;  3LUM A;  3EDG A;  3LK8 A;  3LKA A;  1ZP5 A;  1CXV A;  1QIB A;  1KBC A;  5CUH A;  4XCT A;  2X3C A;  3N2U A; 
#chains in the Genus database with same CATH homology
 3HB2 P;  2O36 A;  2JIH A;  2K2G A;  3LJG A;  2MLR A;  3LIK A;  1BIW A;  1JIZ A;  1OM7 A;  2O3E A;  4GR0 A;  1KAP P;  1PWQ A;  3HBV P;  1DTH A;  4GQL A;  5D1S A;  2XS3 A;  2OXZ A;  1KUH A;  3KME A;  2W13 A;  1J7N A;  1SLM A;  3HDB A;  4H1Q A;  2W12 A;  4A7B A;  1KUF A;  2JSD A;  4A3W A;  3KRY A;  456C A;  1BKC I;  3EHY A;  3WV1 A;  4WZV A;  2SRT A;  3G42 A;  3OHO A;  2DDY A;  3RTT A;  1IAB A;  1KUK A;  3I7I A;  5BOY A;  2OVX A;  3DTK A;  5L79 A;  3LJT A;  1EUB A;  1OS2 A;  1PWP A;  3B8Z A;  1Q3A A;  3BA0 A;  4JQG A;  1HFS A;  3O64 A;  3KMC A;  3MA2 A;  2AYK A;  2Y6D A;  2JNP A;  4H3X A;  1MMP A;  1QJI A;  3LQ0 A;  2USN A;  1CGL A;  5CXA A;  3LIL A;  1UMT A;  1O0Q A;  4I03 A;  4DV8 A;  1BUD A;  2V4B A;  3EDI A;  4PKT A;  1QIC A;  3I7G A;  4DPE A;  2XS4 A;  3F19 A;  3DSL A;  3KEJ A;  1XFV A;  1D8M A;  2W0D A;  1G05 A;  2CKI A;  3F18 A;  1FM1 A;  1D8F A;  4Q1L A;  4G0D A;  1XFX A;  3F1A A;  2J83 A;  1A85 A;  4JP4 A;  2FV9 A;  1YQY A;  1C3I A;  3P24 A;  2OW1 A;  2D1O A;  1R55 A;  1QUA A;  1K7I A;  2ERP A;  3TT4 A;  3ZXH A;  1C7K A;  1SMP A;  3DWB A;  1IAD A;  5B5O A;  966C A;  1D7X A;  5I12 A;  2YB9 A;  3LE9 A;  1DMT A;  1KUI A;  2OW0 A;  1BM6 A;  4ON1 A;  1A86 A;  2OW2 A;  2Y6C A;  4H2E A;  1JAN A;  3RTS A;  5B5P A;  4R3V A;  4GR3 A;  1CQR A;  5I43 A;  5JMY A;  1CAQ A;  4GF1 A;  1OS9 A;  1YP1 A;  3DL1 A;  1PWW A;  4FXY P;  1BQQ M;  1G9K A;  3TVC A;  4WKI A;  3F17 A;  1JK3 A;  5I4O A;  1CGF A;  1IAG A;  1HOV A;  4IJO A;  3HYG A;  4H30 A;  3DNG A;  4AIG A;  4ILW D;  1EAK A;  1XFW A;  4XBH A;  1C8T A;  3DTI A;  1XUR A;  1D5J A;  2WO8 A;  3ELM A;  3O2X A;  1B8Y A;  1UTT A;  4XM7 A;  1RM8 A;  3B92 A;  1GE7 A;  1R1J A;  1GE6 A;  1XUD A;  2L0R A;  1PWU A;  3ZUK A;  2X7M A;  4DD8 A;  1SU3 A;  1I76 A;  1R1H A;  1K7G A;  4PKW A;  5BPA A;  4FVL A;  3VTG A;  1QIA A;  3LUN A;  3SHI A;  1YOU A;  4CTH A;  1UEA A;  2OXU A;  3EHX A;  2TCL A;  5D1U A;  1I1I P;  2MZH A;  1YCM A;  3LGP A;  4H76 A;  3UVC A;  1AYK A;  1K7Q A;  2DW0 A;  3DPE A;  3OHL A;  3GBO A;  2WOA A;  3P1V A;  1JJ9 A;  1FLS A;  3N2V A;  2YUF A;  1HY7 A;  1JAP A;  1ZS0 A;  1XFY A;  1MNC A;  3VI1 A;  3Q2G A;  3WV2 A;  1ROS A;  3CKI A;  1ND1 A;  1R54 A;  2PJT A;  4GUY A;  5H8X A;  3LJZ A;  3AYK A;  5BOT A;  2DW2 A;  3L0V A;  3HY9 A;  4GR8 A;  1MMQ A;  5I0L A;  2YIG A;  3L0T A;  4AXQ A;  1Z3J A;  3LEA A;  2E2D A;  1UTZ A;  4DF9 A;  4H82 A;  1OM8 A;  1AKL A;  1L6J A;  1CK7 A;  3AIG A;  3E8R A;  4J4M A;  3HDA P;  4JPA A;  1BZS A;  2OY2 A;  4PKV A;  2OZR A;  2FV5 A;  1XFU A;  2WO9 A;  3K7L A;  3K7N A;  1IAA A;  1JAO A;  1BQO A;  1JAQ A;  2MZI A;  4PKQ A;  4HX3 A;  3KHI A;  4JIJ A;  1OO9 A;  1PWV A;  1G4K A;  1GXD A;  2HU6 A;  2MLS A;  4JA1 A;  1ATL A;  2AIG P;  2OXW A;  4G9L A;  1GKD A;  4EFS A;  1Y93 A;  2A8H A;  1IAE A;  5D3C A;  1ZVX A;  1QJJ A;  3WV3 A;  3KWV C;  2OI0 A;  1RMZ A;  1HTD A;  3EDH A;  1FBL A;  4PKU A;  4QKZ A;  1G49 A;  3LQB A;  3HY7 A;  2J0T A;  1AST A;  3LIR A;  5LAB A;  3LMC A;  2Z2D A;  2RJQ A;  1AF0 A;  4PKS A;  3KEK A;  4WKE A;  2MZE A;  3F16 A;  4L7A A;  1JKY A;  1XFZ A;  2OY4 A;  830C A;  1G12 A;  1OM6 A;  1MMB A;  1JIW P;  2X3A A;  4L63 A;  3NX7 A;  5I2Z A;  2JT5 A;  2CLT A;  2D1N A;  1SLN A;  2KRJ A;  1B3D A;  2ERQ A;  4GWM A;  4H84 A;  2W15 A;  4AUO A;  3DPF A;  1ZTQ A;  1XUC A;  3EDZ A;  1UMS A;  1O0T A;  5D7W A;  3HBU P;  2RJP A;  5CZM A;  4IUW A;  1I73 A;  1GE5 A;  1ZXC A;  4IN9 A;  3TSK A;  4AYK A;  3EWJ A;  3V96 B;  2E3X A;  4XM8 A;  5D1T A;  4ZR5 A;  1HFC A;  5I3M A;  1R1I A;  4FXQ A;  4FU4 A;  1BUV M;  1SRP A;  4I35 A;  4XM6 A;  2JT6 A;  2ERO A;  2W14 A;  2POJ A;  1H71 P;  3DTE A;  4WK7 A;  5L7F A;  2X3B A;  1KUG A;  3TS4 A;  1GKC A;  4WF6 A;  1OMJ A;  5D2B A;  2OW9 A;  2I47 A;  1Y0V A;  4H49 A;  1EB6 A;  2DDF A;  1BKC A;  1BSW A;  4HMA A;  4GWN A;  4PKR A;  3USN A;  3U1R A;  1SAT A;  3ZVS A;  1CIZ A;  2K9C A;  2N8R A;  1JH1 A;  3KEC A;  1BKC E;  2QPJ A;  2DW1 A;  1MMR A;  1HV5 A;  3AYU A;  3G5C A;  3B2Z A;  1GO7 P;  1S4B P;  1USN A;  4L19 A;  1IAC A;  1ZXV A;  1CGE A;  1WNI A;  3F15 A;  4L6T A;  3Q2H A;  2OVZ A;  1Y8J A;  1GO8 P;  3LUM A;  3EDG A;  3LK8 A;  3LKA A;  1ZP5 A;  1CXV A;  1QIB A;  1KBC A;  5CUH A;  4XCT A;  2X3C A;  3N2U A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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