3LE9A

Crystal structure of the catalytic domain of tace with indazolinone-phenyl-hydantoin inhibitor
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
257
structure length
251
Chain Sequence
PDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYGGHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Biaryl substituted hydantoin compounds as TACE inhibitors.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Disintegrin and metalloproteinase domain-containing protein
total genus 81
structure length 251
sequence length 257
chains with identical sequence B
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2010-01-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3le9A00
1GKDA 1MNCA 2JSDA 1B8YA 3TSKA 1QJJA 3HB2P 1PWWA 1DMTA 1ZVXA 4WK7A 2OW2A 4QKZA 5B5PA 3KHIA 3DPEA 1CGFA 1BUDA 4FXQA 4AXQA 1BM6A 1YQYA 1QUAA 3LILA 4I03A 4L63A 5CUHA 4JA1A 3LJTA 1GO7P 4GR0A 2QPJA 2PJTA 2OI0A 3E8RA 5D7WA 1K7QA 3WV2A 1PWVA 1B3DA 3G42A 1JJ9A 1R1IA 1R1HA 2W15A 1FLSA 2JIHA 3B2ZA 4XBHA 4FVLA 1SLMA 3HY9A 3SHIA 1KBCA 2POJA 3EDZA 3LMCA 1GE6A 4PKUA 1IAGA 1XFXA 3HY7A 1OM6A 1ZXVA 4WF6A 4JP4A 5L79A 1SRPA 1UEAA 1YP1A 4H49A 2DW2A 3HYGA 2K2GA 1G9KA 4GUYA 1UMSA 2CLTA 2J83A 3RTSA 5LABA 3CKIA 1PWUA 2ERQA 1AF0A 3KECA 4PKQA 4AIGA 4XM8A 3UVCA 4L19A 5I43A 4GQLA 5D1SA 1IACA 4A3WA 2TCLA 1Y8JA 1ZS0A 1D7XA 3O64A 1GXDA 1C3IA 3LJZA 1YCMA 3L0VA 4AUOA 3VTGA 1MMBA 1GO8P 3GBOA 3G5CA 1ROSA 3USNA 4CTHA 1MMPA 4I35A 1BQOA 1JKYA 1YOUA 2DW1A 1JK3A 1EAKA 1OS2A 4WKIA 4H30A 3KWVC 4Q1LA 3EHXA 1G12A 3N2UA 1H71P 1EB6A 3LK8A 3LEAA 2AIGP 5BOTA 1IAAA 2K9CA 1XFYA 1S4BP 1G05A 4PKVA 1QJIA 2CKIA 2SRTA 2MLSA 3OHOA 1D8MA 1EUBA 1RMZA 1QIBA 5B5OA 4FXYP 1SATA 1GKCA 1Y0VA 3HBVP 4H82A 1HV5A 3L0TA 1JAOA 3EDGA 2OVXA 2V4BA 1XFVA 1HY7A 4J4MA 3F1AA 3KEJA 2O36A 3F18A 1SLNA 4JQGA 2Z2DA 1BQQM 2D1OA 1HFCA 2OZRA 3LJGA 3I7GA 1XUCA 2EROA 4HMAA 1I1IP 1I76A 3DNGA 1CXVA 1ND1A 1HFSA 5I3MA 1JIZA 1ZP5A 3Q2GA 4GWNA 3ZUKA 4JIJA 3MA2A 1J7NA 5D2BA 1JH1A 3EDIA 3K7LA 2OY4A 3TS4A 3P1VA 4H76A 1HTDA 1CAQA 2YB9A 1K7GA 1CIZA 2W0DA 1UTTA 1L6JA 2OXWA 4DF9A 5D1TA 3AYUA 2Y6CA 1JIWP 3LUNA 966CA 3Q2HA 5I12A 1CQRA 2OW9A 1CGLA 2AYKA 1G4KA 1FM1A 5D3CA 1CGEA 1R1JA 1SU3A 2A8HA 3RTTA 2N8RA 3LIKA 1SMPA 2OXUA 4L6TA 3OHLA 4G9LA 2YIGA 5H8XA 3V96B 1WNIA 3AYKA 1GE7A 3P24A 4PKRA 3ZXHA 3K7NA 1IAEA 4IUWA 4R3VA 1OS9A 3WV3A 3ELMA 3LQ0A 830CA 3LKAA 3EWJA 5L7FA 2WO8A 4JPAA 1HOVA 4HX3A 4DV8A 5CZMA 4AYKA 1D8FA 2FV5A 1UMTA 3O2XA 2X3AA 4EFSA 3LE9A 1I73A 1OMJA 2ERPA 2RJPA 1IABA 1QIAA 3F17A 2DDYA 456CA 1OM8A 3ZVSA 3N2VA 3LQBA 4PKTA 2W14A 4A7BA 1RM8A 4GR8A 1ZTQA 2I47A 3F19A 5CXAA 5I4OA 1BIWA 4H2EA 2KRJA 1ASTA 1FBLA 2E2DA 2JT6A 2E3XA 3F16A 4G0DA 2D1NA 2MZHA 3EHYA 3KRYA 1JANA 4DPEA 1Y93A 5I2ZA 1IADA 3HDBA 2W12A 3KMCA 1KUGA 3AIGA 4XM6A 4PKWA 1XUDA 2OW0A 4WZVA 5JMYA 3VI1A 4H84A 1AYKA 1C8TA 2JNPA 2RJQA 4ILWD 4WKEA 2MLRA 5I0LA 2X3CA 1OO9A 2X3BA 2MZEA 1BKCA 1UTZA 1G49A 2OW1A 1XFUA 1BKCI 1KUIA 4ZR5A 1O0QA 2X7MA 4DD8A 3HDAP 1R55A 3LUMA 3B8ZA 1BKCE 1K7IA 1KUKA 1ATLA 2WOAA 4H3XA 4ON1A 1A86A 1OM7A 1C7KA 4PKSA 1D5JA 1A85A 1R54A 2OY2A 5BOYA 1AKLA 5BPAA 4GWMA 2Y6DA 1ZXCA 3I7IA 1Z3JA 2MZIA 4XCTA 1DTHA 1O0TA 4H1QA 2WO9A 3EDHA 3TT4A 1BSWA 1PWPA 2OVZA 3HBUP 1BUVM 1BZSA 1CK7A 3KMEA 1JAQA 2XS4A 2O3EA 1KUFA 2DW0A 4GR3A 3B92A 2DDFA 1MMQA 2HU6A 3F15A 1GE5A 1XURA 1USNA 1QICA 1KUHA 3LGPA 3BA0A 3TVCA 3NX7A 1MMRA 1Q3AA 2W13A 4FU4A 1XFZA 3U1RA 3DPFA 5D1UA 3KEKA 2USNA 4IJOA 3WV1A 2FV9A 3DL1A 3LIRA 2XS3A 1KAPP 1PWQA 2L0RA 4GF1A 4IN9A 4XM7A 3DWBA 1XFWA 2J0TA 2JT5A 3DSLA 2OXZA 1JAPA
chains in the Genus database with same CATH superfamily
1GKDA 1MNCA 2JSDA 1B8YA 3TSKA 1QJJA 3HB2P 1PWWA 1DMTA 1ZVXA 4WK7A 2OW2A 4QKZA 5B5PA 3KHIA 3DPEA 1CGFA 1BUDA 4FXQA 4AXQA 1BM6A 1YQYA 1QUAA 3LILA 4I03A 4L63A 5CUHA 4JA1A 4L7AA 3LJTA 1GO7P 4GR0A 2QPJA 2PJTA 2OI0A 3E8RA 5D7WA 1K7QA 1XM5A 3WV2A 1PWVA 1B3DA 3G42A 1JJ9A 1R1IA 1R1HA 2W15A 1FLSA 2JIHA 3B2ZA 4XBHA 4FVLA 1SLMA 3HY9A 3SHIA 1KBCA 2POJA 3EDZA 3LMCA 1GE6A 4PKUA 1IAGA 1XFXA 3HY7A 1OM6A 1ZXVA 4WF6A 4JP4A 5L79A 1SRPA 1UEAA 1YP1A 4H49A 2DW2A 3HYGA 2K2GA 1G9KA 4GUYA 1UMSA 2CLTA 2J83A 3RTSA 5LABA 3CKIA 1PWUA 2ERQA 1AF0A 3KECA 4PKQA 4AIGA 4XM8A 3UVCA 4L19A 5I43A 4GQLA 5D1SA 1IACA 4A3WA 2TCLA 1Y8JA 1ZS0A 1D7XA 3DTKA 3O64A 1GXDA 1C3IA 3LJZA 1YCMA 3L0VA 4AUOA 3VTGA 1MMBA 1GO8P 3GBOA 3G5CA 1ROSA 3USNA 4CTHA 1MMPA 4I35A 1BQOA 1JKYA 1YOUA 2DW1A 1JK3A 1EAKA 1OS2A 4WKIA 4H30A 3KWVC 4Q1LA 3EHXA 1G12A 3N2UA 1H71P 1EB6A 3LK8A 1OZ9A 3LEAA 2AIGP 5BOTA 1IAAA 2K9CA 1XFYA 1S4BP 1G05A 4PKVA 1QJIA 2CKIA 2SRTA 2MLSA 3OHOA 1D8MA 1EUBA 1RMZA 1QIBA 5B5OA 4FXYP 1SATA 1GKCA 1Y0VA 3HBVP 4H82A 1HV5A 3L0TA 1JAOA 3EDGA 2OVXA 2V4BA 1XFVA 1HY7A 4J4MA 3F1AA 3KEJA 2O36A 3F18A 1SLNA 4JQGA 2Z2DA 1BQQM 2D1OA 1HFCA 2OZRA 3LJGA 3I7GA 1XUCA 2EROA 4HMAA 1I1IP 1I76A 3DNGA 1CXVA 1ND1A 2YUFA 1HFSA 5I3MA 1JIZA 1ZP5A 3Q2GA 4GWNA 3ZUKA 4JIJA 3MA2A 1J7NA 5D2BA 1JH1A 3EDIA 3K7LA 2OY4A 3TS4A 3P1VA 4H76A 1HTDA 1CAQA 2YB9A 1K7GA 1CIZA 2W0DA 1UTTA 1L6JA 2OXWA 4DF9A 5D1TA 3AYUA 2Y6CA 1JIWP 3LUNA 966CA 3Q2HA 5I12A 1CQRA 2OW9A 1CGLA 2AYKA 1G4KA 1FM1A 5D3CA 1CGEA 1R1JA 1SU3A 2A8HA 3RTTA 2N8RA 3LIKA 1SMPA 2OXUA 4L6TA 3OHLA 4G9LA 2YIGA 5H8XA 3V96B 1WNIA 3AYKA 1GE7A 3P24A 4PKRA 3ZXHA 3K7NA 1IAEA 4IUWA 4R3VA 1OS9A 3WV3A 3ELMA 3LQ0A 830CA 3LKAA 3EWJA 5L7FA 2WO8A 4JPAA 1HOVA 4HX3A 4DV8A 5CZMA 4AYKA 1D8FA 2FV5A 1UMTA 3O2XA 2X3AA 4EFSA 3LE9A 1I73A 1OMJA 2ERPA 2RJPA 1IABA 1QIAA 3F17A 2DDYA 456CA 1OM8A 3ZVSA 3N2VA 3LQBA 4PKTA 2W14A 4A7BA 1RM8A 4GR8A 1ZTQA 2I47A 3F19A 5CXAA 5I4OA 1BIWA 4H2EA 2KRJA 1ASTA 1FBLA 2E2DA 2JT6A 2E3XA 3F16A 4G0DA 2D1NA 2MZHA 3EHYA 3KRYA 1JANA 4DPEA 1Y93A 5I2ZA 1IADA 3HDBA 2W12A 3KMCA 1KUGA 3AIGA 4XM6A 4PKWA 1XUDA 2OW0A 4WZVA 5JMYA 3VI1A 4H84A 1AYKA 1C8TA 2JNPA 2RJQA 4ILWD 3DTEA 4WKEA 2MLRA 5I0LA 2X3CA 1OO9A 2X3BA 2MZEA 1BKCA 1UTZA 1G49A 2OW1A 1XFUA 1BKCI 1KUIA 4ZR5A 1O0QA 2X7MA 4DD8A 3HDAP 1R55A 3LUMA 3B8ZA 1BKCE 1K7IA 1KUKA 1ATLA 2WOAA 4H3XA 4ON1A 1A86A 1OM7A 1C7KA 4PKSA 1D5JA 1XAXA 1A85A 1R54A 2OY2A 5BOYA 1AKLA 5BPAA 4GWMA 2Y6DA 1ZXCA 3I7IA 1Z3JA 2MZIA 4XCTA 1TVIA 1DTHA 1O0TA 4H1QA 2WO9A 3EDHA 3TT4A 1BSWA 1PWPA 2OVZA 3HBUP 1BUVM 1BZSA 1CK7A 3KMEA 1JAQA 2XS4A 2O3EA 1KUFA 2DW0A 4GR3A 3B92A 2DDFA 1MMQA 2HU6A 3F15A 1GE5A 1XURA 1USNA 1QICA 1KUHA 3LGPA 3BA0A 3TVCA 3NX7A 1MMRA 1Q3AA 2W13A 3DTIA 4FU4A 1XFZA 3U1RA 3DPFA 5D1UA 3KEKA 2USNA 4IJOA 3WV1A 2FV9A 3DL1A 3LIRA 2XS3A 1KAPP 1PWQA 2L0RA 4GF1A 4IN9A 4XM7A 3DWBA 1XFWA 2J0TA 2JT5A 3DSLA 2OXZA 1JAPA
chains in the Genus database with same CATH topology
1GKDA 1MNCA 2JSDA 1B8YA 3TSKA 1QJJA 3HB2P 1PWWA 1DMTA 1ZVXA 4WK7A 2OW2A 4QKZA 5B5PA 3KHIA 3DPEA 1CGFA 1BUDA 4FXQA 4AXQA 1BM6A 1YQYA 1QUAA 3LILA 4I03A 4L63A 5CUHA 4JA1A 4L7AA 3LJTA 1GO7P 4GR0A 2QPJA 2PJTA 2OI0A 3E8RA 5D7WA 1K7QA 3WV2A 1PWVA 1B3DA 3G42A 1JJ9A 1R1IA 1R1HA 2W15A 1FLSA 2JIHA 3B2ZA 4XBHA 4FVLA 1SLMA 3HY9A 3SHIA 1KBCA 2POJA 3EDZA 3LMCA 1GE6A 4PKUA 1IAGA 1XFXA 3HY7A 1OM6A 1ZXVA 4WF6A 4JP4A 5L79A 1SRPA 1UEAA 1YP1A 4H49A 2DW2A 3HYGA 2K2GA 1G9KA 4GUYA 1UMSA 2CLTA 2J83A 3RTSA 5LABA 3CKIA 1PWUA 2ERQA 1AF0A 3KECA 4PKQA 4AIGA 4XM8A 3UVCA 4L19A 5I43A 4GQLA 5D1SA 1IACA 4A3WA 2TCLA 1Y8JA 1ZS0A 1D7XA 3DTKA 3O64A 1GXDA 1C3IA 3LJZA 1YCMA 3L0VA 4AUOA 3VTGA 1MMBA 1GO8P 3GBOA 3G5CA 1ROSA 3USNA 4CTHA 1MMPA 4I35A 1BQOA 1JKYA 1YOUA 2DW1A 1JK3A 1EAKA 1OS2A 4WKIA 4H30A 3KWVC 4Q1LA 3EHXA 1G12A 3N2UA 1H71P 1EB6A 3LK8A 3LEAA 2AIGP 5BOTA 1IAAA 2K9CA 1XFYA 1S4BP 1G05A 4PKVA 1QJIA 2CKIA 2SRTA 2MLSA 3OHOA 1D8MA 1EUBA 1RMZA 1QIBA 5B5OA 4FXYP 1SATA 1GKCA 1Y0VA 3HBVP 4H82A 1HV5A 3L0TA 1JAOA 3EDGA 2OVXA 2V4BA 1XFVA 1HY7A 4J4MA 3F1AA 3KEJA 2O36A 3F18A 1SLNA 4JQGA 2Z2DA 1BQQM 2D1OA 1HFCA 2OZRA 3LJGA 3I7GA 1XUCA 2EROA 4HMAA 1I1IP 1I76A 3DNGA 1CXVA 1ND1A 2YUFA 1HFSA 5I3MA 1JIZA 1ZP5A 3Q2GA 4GWNA 3ZUKA 4JIJA 3MA2A 1J7NA 5D2BA 1JH1A 3EDIA 3K7LA 2OY4A 3TS4A 3P1VA 4H76A 1HTDA 1CAQA 2YB9A 1K7GA 1CIZA 2W0DA 1UTTA 1L6JA 2OXWA 4DF9A 5D1TA 3AYUA 2Y6CA 1JIWP 3LUNA 966CA 3Q2HA 5I12A 1CQRA 2OW9A 1CGLA 2AYKA 1G4KA 1FM1A 5D3CA 1CGEA 1R1JA 1SU3A 2A8HA 3RTTA 2N8RA 3LIKA 1SMPA 2OXUA 4L6TA 3OHLA 4G9LA 2YIGA 5H8XA 3V96B 1WNIA 3AYKA 1GE7A 3P24A 4PKRA 3ZXHA 3K7NA 1IAEA 4IUWA 4R3VA 1OS9A 3WV3A 3ELMA 3LQ0A 830CA 3LKAA 3EWJA 5L7FA 2WO8A 4JPAA 1HOVA 4HX3A 4DV8A 5CZMA 4AYKA 1D8FA 2FV5A 1UMTA 3O2XA 2X3AA 4EFSA 3LE9A 1I73A 1OMJA 2ERPA 2RJPA 1IABA 1QIAA 3F17A 2DDYA 456CA 1OM8A 3ZVSA 3N2VA 3LQBA 4PKTA 2W14A 4A7BA 1RM8A 4GR8A 1ZTQA 2I47A 3F19A 5CXAA 5I4OA 1BIWA 4H2EA 2KRJA 1ASTA 1FBLA 2E2DA 2JT6A 2E3XA 3F16A 4G0DA 2D1NA 2MZHA 3EHYA 3KRYA 1JANA 4DPEA 1Y93A 5I2ZA 1IADA 3HDBA 2W12A 3KMCA 1KUGA 3AIGA 4XM6A 4PKWA 1XUDA 2OW0A 4WZVA 5JMYA 3VI1A 4H84A 1AYKA 1C8TA 2JNPA 2RJQA 4ILWD 3DTEA 4WKEA 2MLRA 5I0LA 2X3CA 1OO9A 2X3BA 2MZEA 1BKCA 1UTZA 1G49A 2OW1A 1XFUA 1BKCI 1KUIA 4ZR5A 1O0QA 2X7MA 4DD8A 3HDAP 1R55A 3LUMA 3B8ZA 1BKCE 1K7IA 1KUKA 1ATLA 2WOAA 4H3XA 4ON1A 1A86A 1OM7A 1C7KA 4PKSA 1D5JA 1A85A 1R54A 2OY2A 5BOYA 1AKLA 5BPAA 4GWMA 2Y6DA 1ZXCA 3I7IA 1Z3JA 2MZIA 4XCTA 1DTHA 1O0TA 4H1QA 2WO9A 3EDHA 3TT4A 1BSWA 1PWPA 2OVZA 3HBUP 1BUVM 1BZSA 1CK7A 3KMEA 1JAQA 2XS4A 2O3EA 1KUFA 2DW0A 4GR3A 3B92A 2DDFA 1MMQA 2HU6A 3F15A 1GE5A 1XURA 1USNA 1QICA 1KUHA 3LGPA 3BA0A 3TVCA 3NX7A 1MMRA 1Q3AA 2W13A 3DTIA 4FU4A 1XFZA 3U1RA 3DPFA 5D1UA 3KEKA 2USNA 4IJOA 3WV1A 2FV9A 3DL1A 3LIRA 2XS3A 1KAPP 1PWQA 2L0RA 4GF1A 4IN9A 4XM7A 3DWBA 1XFWA 2J0TA 2JT5A 3DSLA 2OXZA 1JAPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GKD A;  1MNC A;  2JSD A;  1B8Y A;  3TSK A;  1QJJ A;  3HB2 P;  1PWW A;  1DMT A;  1ZVX A;  4WK7 A;  2OW2 A;  4QKZ A;  5B5P A;  3KHI A;  3DPE A;  1CGF A;  1BUD A;  4FXQ A;  4AXQ A;  1BM6 A;  1YQY A;  1QUA A;  3LIL A;  4I03 A;  4L63 A;  5CUH A;  4JA1 A;  3LJT A;  1GO7 P;  4GR0 A;  2QPJ A;  2PJT A;  2OI0 A;  3E8R A;  5D7W A;  1K7Q A;  3WV2 A;  1PWV A;  1B3D A;  3G42 A;  1JJ9 A;  1R1I A;  1R1H A;  2W15 A;  1FLS A;  2JIH A;  3B2Z A;  4XBH A;  4FVL A;  1SLM A;  3HY9 A;  3SHI A;  1KBC A;  2POJ A;  3EDZ A;  3LMC A;  1GE6 A;  4PKU A;  1IAG A;  1XFX A;  3HY7 A;  1OM6 A;  1ZXV A;  4WF6 A;  4JP4 A;  5L79 A;  1SRP A;  1UEA A;  1YP1 A;  4H49 A;  2DW2 A;  3HYG A;  2K2G A;  1G9K A;  4GUY A;  1UMS A;  2CLT A;  2J83 A;  3RTS A;  5LAB A;  3CKI A;  1PWU A;  2ERQ A;  1AF0 A;  3KEC A;  4PKQ A;  4AIG A;  4XM8 A;  3UVC A;  4L19 A;  5I43 A;  4GQL A;  5D1S A;  1IAC A;  4A3W A;  2TCL A;  1Y8J A;  1ZS0 A;  1D7X A;  3O64 A;  1GXD A;  1C3I A;  3LJZ A;  1YCM A;  3L0V A;  4AUO A;  3VTG A;  1MMB A;  1GO8 P;  3GBO A;  3G5C A;  1ROS A;  3USN A;  4CTH A;  1MMP A;  4I35 A;  1BQO A;  1JKY A;  1YOU A;  2DW1 A;  1JK3 A;  1EAK A;  1OS2 A;  4WKI A;  4H30 A;  3KWV C;  4Q1L A;  3EHX A;  1G12 A;  3N2U A;  1H71 P;  1EB6 A;  3LK8 A;  3LEA A;  2AIG P;  5BOT A;  1IAA A;  2K9C A;  1XFY A;  1S4B P;  1G05 A;  4PKV A;  1QJI A;  2CKI A;  2SRT A;  2MLS A;  3OHO A;  1D8M A;  1EUB A;  1RMZ A;  1QIB A;  5B5O A;  4FXY P;  1SAT A;  1GKC A;  1Y0V A;  3HBV P;  4H82 A;  1HV5 A;  3L0T A;  1JAO A;  3EDG A;  2OVX A;  2V4B A;  1XFV A;  1HY7 A;  4J4M A;  3F1A A;  3KEJ A;  2O36 A;  3F18 A;  1SLN A;  4JQG A;  2Z2D A;  1BQQ M;  2D1O A;  1HFC A;  2OZR A;  3LJG A;  3I7G A;  1XUC A;  2ERO A;  4HMA A;  1I1I P;  1I76 A;  3DNG A;  1CXV A;  1ND1 A;  1HFS A;  5I3M A;  1JIZ A;  1ZP5 A;  3Q2G A;  4GWN A;  3ZUK A;  4JIJ A;  3MA2 A;  1J7N A;  5D2B A;  1JH1 A;  3EDI A;  3K7L A;  2OY4 A;  3TS4 A;  3P1V A;  4H76 A;  1HTD A;  1CAQ A;  2YB9 A;  1K7G A;  1CIZ A;  2W0D A;  1UTT A;  1L6J A;  2OXW A;  4DF9 A;  5D1T A;  3AYU A;  2Y6C A;  1JIW P;  3LUN A;  966C A;  3Q2H A;  5I12 A;  1CQR A;  2OW9 A;  1CGL A;  2AYK A;  1G4K A;  1FM1 A;  5D3C A;  1CGE A;  1R1J A;  1SU3 A;  2A8H A;  3RTT A;  2N8R A;  3LIK A;  1SMP A;  2OXU A;  4L6T A;  3OHL A;  4G9L A;  2YIG A;  5H8X A;  3V96 B;  1WNI A;  3AYK A;  1GE7 A;  3P24 A;  4PKR A;  3ZXH A;  3K7N A;  1IAE A;  4IUW A;  4R3V A;  1OS9 A;  3WV3 A;  3ELM A;  3LQ0 A;  830C A;  3LKA A;  3EWJ A;  5L7F A;  2WO8 A;  4JPA A;  1HOV A;  4HX3 A;  4DV8 A;  5CZM A;  4AYK A;  1D8F A;  2FV5 A;  1UMT A;  3O2X A;  2X3A A;  4EFS A;  3LE9 A;  1I73 A;  1OMJ A;  2ERP A;  2RJP A;  1IAB A;  1QIA A;  3F17 A;  2DDY A;  456C A;  1OM8 A;  3ZVS A;  3N2V A;  3LQB A;  4PKT A;  2W14 A;  4A7B A;  1RM8 A;  4GR8 A;  1ZTQ A;  2I47 A;  3F19 A;  5CXA A;  5I4O A;  1BIW A;  4H2E A;  2KRJ A;  1AST A;  1FBL A;  2E2D A;  2JT6 A;  2E3X A;  3F16 A;  4G0D A;  2D1N A;  2MZH A;  3EHY A;  3KRY A;  1JAN A;  4DPE A;  1Y93 A;  5I2Z A;  1IAD A;  3HDB A;  2W12 A;  3KMC A;  1KUG A;  3AIG A;  4XM6 A;  4PKW A;  1XUD A;  2OW0 A;  4WZV A;  5JMY A;  3VI1 A;  4H84 A;  1AYK A;  1C8T A;  2JNP A;  2RJQ A;  4ILW D;  4WKE A;  2MLR A;  5I0L A;  2X3C A;  1OO9 A;  2X3B A;  2MZE A;  1BKC A;  1UTZ A;  1G49 A;  2OW1 A;  1XFU A;  1BKC I;  1KUI A;  4ZR5 A;  1O0Q A;  2X7M A;  4DD8 A;  3HDA P;  1R55 A;  3LUM A;  3B8Z A;  1BKC E;  1K7I A;  1KUK A;  1ATL A;  2WOA A;  4H3X A;  4ON1 A;  1A86 A;  1OM7 A;  1C7K A;  4PKS A;  1D5J A;  1A85 A;  1R54 A;  2OY2 A;  5BOY A;  1AKL A;  5BPA A;  4GWM A;  2Y6D A;  1ZXC A;  3I7I A;  1Z3J A;  2MZI A;  4XCT A;  1DTH A;  1O0T A;  4H1Q A;  2WO9 A;  3EDH A;  3TT4 A;  1BSW A;  1PWP A;  2OVZ A;  3HBU P;  1BUV M;  1BZS A;  1CK7 A;  3KME A;  1JAQ A;  2XS4 A;  2O3E A;  1KUF A;  2DW0 A;  4GR3 A;  3B92 A;  2DDF A;  1MMQ A;  2HU6 A;  3F15 A;  1GE5 A;  1XUR A;  1USN A;  1QIC A;  1KUH A;  3LGP A;  3BA0 A;  3TVC A;  3NX7 A;  1MMR A;  1Q3A A;  2W13 A;  4FU4 A;  1XFZ A;  3U1R A;  3DPF A;  5D1U A;  3KEK A;  2USN A;  4IJO A;  3WV1 A;  2FV9 A;  3DL1 A;  3LIR A;  2XS3 A;  1KAP P;  1PWQ A;  2L0R A;  4GF1 A;  4IN9 A;  4XM7 A;  3DWB A;  1XFW A;  2J0T A;  2JT5 A;  3DSL A;  2OXZ A;  1JAP A; 
#chains in the Genus database with same CATH topology
 1GKD A;  1MNC A;  2JSD A;  1B8Y A;  3TSK A;  1QJJ A;  3HB2 P;  1PWW A;  1DMT A;  1ZVX A;  4WK7 A;  2OW2 A;  4QKZ A;  5B5P A;  3KHI A;  3DPE A;  1CGF A;  1BUD A;  4FXQ A;  4AXQ A;  1BM6 A;  1YQY A;  1QUA A;  3LIL A;  4I03 A;  4L63 A;  5CUH A;  4JA1 A;  4L7A A;  3LJT A;  1GO7 P;  4GR0 A;  2QPJ A;  2PJT A;  2OI0 A;  3E8R A;  5D7W A;  1K7Q A;  1XM5 A;  3WV2 A;  1PWV A;  1B3D A;  3G42 A;  1JJ9 A;  1R1I A;  1R1H A;  2W15 A;  1FLS A;  2JIH A;  3B2Z A;  4XBH A;  4FVL A;  1SLM A;  3HY9 A;  3SHI A;  1KBC A;  2POJ A;  3EDZ A;  3LMC A;  1GE6 A;  4PKU A;  1IAG A;  1XFX A;  3HY7 A;  1OM6 A;  1ZXV A;  4WF6 A;  4JP4 A;  5L79 A;  1SRP A;  1UEA A;  1YP1 A;  4H49 A;  2DW2 A;  3HYG A;  2K2G A;  1G9K A;  4GUY A;  1UMS A;  2CLT A;  2J83 A;  3RTS A;  5LAB A;  3CKI A;  1PWU A;  2ERQ A;  1AF0 A;  3KEC A;  4PKQ A;  4AIG A;  4XM8 A;  3UVC A;  4L19 A;  5I43 A;  4GQL A;  5D1S A;  1IAC A;  4A3W A;  2TCL A;  1Y8J A;  1ZS0 A;  1D7X A;  3DTK A;  3O64 A;  1GXD A;  1C3I A;  3LJZ A;  1YCM A;  3L0V A;  4AUO A;  3VTG A;  1MMB A;  1GO8 P;  3GBO A;  3G5C A;  1ROS A;  3USN A;  4CTH A;  1MMP A;  4I35 A;  1BQO A;  1JKY A;  1YOU A;  2DW1 A;  1JK3 A;  1EAK A;  1OS2 A;  4WKI A;  4H30 A;  3KWV C;  4Q1L A;  3EHX A;  1G12 A;  3N2U A;  1H71 P;  1EB6 A;  3LK8 A;  1OZ9 A;  3LEA A;  2AIG P;  5BOT A;  1IAA A;  2K9C A;  1XFY A;  1S4B P;  1G05 A;  4PKV A;  1QJI A;  2CKI A;  2SRT A;  2MLS A;  3OHO A;  1D8M A;  1EUB A;  1RMZ A;  1QIB A;  5B5O A;  4FXY P;  1SAT A;  1GKC A;  1Y0V A;  3HBV P;  4H82 A;  1HV5 A;  3L0T A;  1JAO A;  3EDG A;  2OVX A;  2V4B A;  1XFV A;  1HY7 A;  4J4M A;  3F1A A;  3KEJ A;  2O36 A;  3F18 A;  1SLN A;  4JQG A;  2Z2D A;  1BQQ M;  2D1O A;  1HFC A;  2OZR A;  3LJG A;  3I7G A;  1XUC A;  2ERO A;  4HMA A;  1I1I P;  1I76 A;  3DNG A;  1CXV A;  1ND1 A;  2YUF A;  1HFS A;  5I3M A;  1JIZ A;  1ZP5 A;  3Q2G A;  4GWN A;  3ZUK A;  4JIJ A;  3MA2 A;  1J7N A;  5D2B A;  1JH1 A;  3EDI A;  3K7L A;  2OY4 A;  3TS4 A;  3P1V A;  4H76 A;  1HTD A;  1CAQ A;  2YB9 A;  1K7G A;  1CIZ A;  2W0D A;  1UTT A;  1L6J A;  2OXW A;  4DF9 A;  5D1T A;  3AYU A;  2Y6C A;  1JIW P;  3LUN A;  966C A;  3Q2H A;  5I12 A;  1CQR A;  2OW9 A;  1CGL A;  2AYK A;  1G4K A;  1FM1 A;  5D3C A;  1CGE A;  1R1J A;  1SU3 A;  2A8H A;  3RTT A;  2N8R A;  3LIK A;  1SMP A;  2OXU A;  4L6T A;  3OHL A;  4G9L A;  2YIG A;  5H8X A;  3V96 B;  1WNI A;  3AYK A;  1GE7 A;  3P24 A;  4PKR A;  3ZXH A;  3K7N A;  1IAE A;  4IUW A;  4R3V A;  1OS9 A;  3WV3 A;  3ELM A;  3LQ0 A;  830C A;  3LKA A;  3EWJ A;  5L7F A;  2WO8 A;  4JPA A;  1HOV A;  4HX3 A;  4DV8 A;  5CZM A;  4AYK A;  1D8F A;  2FV5 A;  1UMT A;  3O2X A;  2X3A A;  4EFS A;  3LE9 A;  1I73 A;  1OMJ A;  2ERP A;  2RJP A;  1IAB A;  1QIA A;  3F17 A;  2DDY A;  456C A;  1OM8 A;  3ZVS A;  3N2V A;  3LQB A;  4PKT A;  2W14 A;  4A7B A;  1RM8 A;  4GR8 A;  1ZTQ A;  2I47 A;  3F19 A;  5CXA A;  5I4O A;  1BIW A;  4H2E A;  2KRJ A;  1AST A;  1FBL A;  2E2D A;  2JT6 A;  2E3X A;  3F16 A;  4G0D A;  2D1N A;  2MZH A;  3EHY A;  3KRY A;  1JAN A;  4DPE A;  1Y93 A;  5I2Z A;  1IAD A;  3HDB A;  2W12 A;  3KMC A;  1KUG A;  3AIG A;  4XM6 A;  4PKW A;  1XUD A;  2OW0 A;  4WZV A;  5JMY A;  3VI1 A;  4H84 A;  1AYK A;  1C8T A;  2JNP A;  2RJQ A;  4ILW D;  3DTE A;  4WKE A;  2MLR A;  5I0L A;  2X3C A;  1OO9 A;  2X3B A;  2MZE A;  1BKC A;  1UTZ A;  1G49 A;  2OW1 A;  1XFU A;  1BKC I;  1KUI A;  4ZR5 A;  1O0Q A;  2X7M A;  4DD8 A;  3HDA P;  1R55 A;  3LUM A;  3B8Z A;  1BKC E;  1K7I A;  1KUK A;  1ATL A;  2WOA A;  4H3X A;  4ON1 A;  1A86 A;  1OM7 A;  1C7K A;  4PKS A;  1D5J A;  1XAX A;  1A85 A;  1R54 A;  2OY2 A;  5BOY A;  1AKL A;  5BPA A;  4GWM A;  2Y6D A;  1ZXC A;  3I7I A;  1Z3J A;  2MZI A;  4XCT A;  1TVI A;  1DTH A;  1O0T A;  4H1Q A;  2WO9 A;  3EDH A;  3TT4 A;  1BSW A;  1PWP A;  2OVZ A;  3HBU P;  1BUV M;  1BZS A;  1CK7 A;  3KME A;  1JAQ A;  2XS4 A;  2O3E A;  1KUF A;  2DW0 A;  4GR3 A;  3B92 A;  2DDF A;  1MMQ A;  2HU6 A;  3F15 A;  1GE5 A;  1XUR A;  1USN A;  1QIC A;  1KUH A;  3LGP A;  3BA0 A;  3TVC A;  3NX7 A;  1MMR A;  1Q3A A;  2W13 A;  3DTI A;  4FU4 A;  1XFZ A;  3U1R A;  3DPF A;  5D1U A;  3KEK A;  2USN A;  4IJO A;  3WV1 A;  2FV9 A;  3DL1 A;  3LIR A;  2XS3 A;  1KAP P;  1PWQ A;  2L0R A;  4GF1 A;  4IN9 A;  4XM7 A;  3DWB A;  1XFW A;  2J0T A;  2JT5 A;  3DSL A;  2OXZ A;  1JAP A; 
#chains in the Genus database with same CATH homology
 1GKD A;  1MNC A;  2JSD A;  1B8Y A;  3TSK A;  1QJJ A;  3HB2 P;  1PWW A;  1DMT A;  1ZVX A;  4WK7 A;  2OW2 A;  4QKZ A;  5B5P A;  3KHI A;  3DPE A;  1CGF A;  1BUD A;  4FXQ A;  4AXQ A;  1BM6 A;  1YQY A;  1QUA A;  3LIL A;  4I03 A;  4L63 A;  5CUH A;  4JA1 A;  4L7A A;  3LJT A;  1GO7 P;  4GR0 A;  2QPJ A;  2PJT A;  2OI0 A;  3E8R A;  5D7W A;  1K7Q A;  3WV2 A;  1PWV A;  1B3D A;  3G42 A;  1JJ9 A;  1R1I A;  1R1H A;  2W15 A;  1FLS A;  2JIH A;  3B2Z A;  4XBH A;  4FVL A;  1SLM A;  3HY9 A;  3SHI A;  1KBC A;  2POJ A;  3EDZ A;  3LMC A;  1GE6 A;  4PKU A;  1IAG A;  1XFX A;  3HY7 A;  1OM6 A;  1ZXV A;  4WF6 A;  4JP4 A;  5L79 A;  1SRP A;  1UEA A;  1YP1 A;  4H49 A;  2DW2 A;  3HYG A;  2K2G A;  1G9K A;  4GUY A;  1UMS A;  2CLT A;  2J83 A;  3RTS A;  5LAB A;  3CKI A;  1PWU A;  2ERQ A;  1AF0 A;  3KEC A;  4PKQ A;  4AIG A;  4XM8 A;  3UVC A;  4L19 A;  5I43 A;  4GQL A;  5D1S A;  1IAC A;  4A3W A;  2TCL A;  1Y8J A;  1ZS0 A;  1D7X A;  3DTK A;  3O64 A;  1GXD A;  1C3I A;  3LJZ A;  1YCM A;  3L0V A;  4AUO A;  3VTG A;  1MMB A;  1GO8 P;  3GBO A;  3G5C A;  1ROS A;  3USN A;  4CTH A;  1MMP A;  4I35 A;  1BQO A;  1JKY A;  1YOU A;  2DW1 A;  1JK3 A;  1EAK A;  1OS2 A;  4WKI A;  4H30 A;  3KWV C;  4Q1L A;  3EHX A;  1G12 A;  3N2U A;  1H71 P;  1EB6 A;  3LK8 A;  3LEA A;  2AIG P;  5BOT A;  1IAA A;  2K9C A;  1XFY A;  1S4B P;  1G05 A;  4PKV A;  1QJI A;  2CKI A;  2SRT A;  2MLS A;  3OHO A;  1D8M A;  1EUB A;  1RMZ A;  1QIB A;  5B5O A;  4FXY P;  1SAT A;  1GKC A;  1Y0V A;  3HBV P;  4H82 A;  1HV5 A;  3L0T A;  1JAO A;  3EDG A;  2OVX A;  2V4B A;  1XFV A;  1HY7 A;  4J4M A;  3F1A A;  3KEJ A;  2O36 A;  3F18 A;  1SLN A;  4JQG A;  2Z2D A;  1BQQ M;  2D1O A;  1HFC A;  2OZR A;  3LJG A;  3I7G A;  1XUC A;  2ERO A;  4HMA A;  1I1I P;  1I76 A;  3DNG A;  1CXV A;  1ND1 A;  2YUF A;  1HFS A;  5I3M A;  1JIZ A;  1ZP5 A;  3Q2G A;  4GWN A;  3ZUK A;  4JIJ A;  3MA2 A;  1J7N A;  5D2B A;  1JH1 A;  3EDI A;  3K7L A;  2OY4 A;  3TS4 A;  3P1V A;  4H76 A;  1HTD A;  1CAQ A;  2YB9 A;  1K7G A;  1CIZ A;  2W0D A;  1UTT A;  1L6J A;  2OXW A;  4DF9 A;  5D1T A;  3AYU A;  2Y6C A;  1JIW P;  3LUN A;  966C A;  3Q2H A;  5I12 A;  1CQR A;  2OW9 A;  1CGL A;  2AYK A;  1G4K A;  1FM1 A;  5D3C A;  1CGE A;  1R1J A;  1SU3 A;  2A8H A;  3RTT A;  2N8R A;  3LIK A;  1SMP A;  2OXU A;  4L6T A;  3OHL A;  4G9L A;  2YIG A;  5H8X A;  3V96 B;  1WNI A;  3AYK A;  1GE7 A;  3P24 A;  4PKR A;  3ZXH A;  3K7N A;  1IAE A;  4IUW A;  4R3V A;  1OS9 A;  3WV3 A;  3ELM A;  3LQ0 A;  830C A;  3LKA A;  3EWJ A;  5L7F A;  2WO8 A;  4JPA A;  1HOV A;  4HX3 A;  4DV8 A;  5CZM A;  4AYK A;  1D8F A;  2FV5 A;  1UMT A;  3O2X A;  2X3A A;  4EFS A;  3LE9 A;  1I73 A;  1OMJ A;  2ERP A;  2RJP A;  1IAB A;  1QIA A;  3F17 A;  2DDY A;  456C A;  1OM8 A;  3ZVS A;  3N2V A;  3LQB A;  4PKT A;  2W14 A;  4A7B A;  1RM8 A;  4GR8 A;  1ZTQ A;  2I47 A;  3F19 A;  5CXA A;  5I4O A;  1BIW A;  4H2E A;  2KRJ A;  1AST A;  1FBL A;  2E2D A;  2JT6 A;  2E3X A;  3F16 A;  4G0D A;  2D1N A;  2MZH A;  3EHY A;  3KRY A;  1JAN A;  4DPE A;  1Y93 A;  5I2Z A;  1IAD A;  3HDB A;  2W12 A;  3KMC A;  1KUG A;  3AIG A;  4XM6 A;  4PKW A;  1XUD A;  2OW0 A;  4WZV A;  5JMY A;  3VI1 A;  4H84 A;  1AYK A;  1C8T A;  2JNP A;  2RJQ A;  4ILW D;  3DTE A;  4WKE A;  2MLR A;  5I0L A;  2X3C A;  1OO9 A;  2X3B A;  2MZE A;  1BKC A;  1UTZ A;  1G49 A;  2OW1 A;  1XFU A;  1BKC I;  1KUI A;  4ZR5 A;  1O0Q A;  2X7M A;  4DD8 A;  3HDA P;  1R55 A;  3LUM A;  3B8Z A;  1BKC E;  1K7I A;  1KUK A;  1ATL A;  2WOA A;  4H3X A;  4ON1 A;  1A86 A;  1OM7 A;  1C7K A;  4PKS A;  1D5J A;  1A85 A;  1R54 A;  2OY2 A;  5BOY A;  1AKL A;  5BPA A;  4GWM A;  2Y6D A;  1ZXC A;  3I7I A;  1Z3J A;  2MZI A;  4XCT A;  1DTH A;  1O0T A;  4H1Q A;  2WO9 A;  3EDH A;  3TT4 A;  1BSW A;  1PWP A;  2OVZ A;  3HBU P;  1BUV M;  1BZS A;  1CK7 A;  3KME A;  1JAQ A;  2XS4 A;  2O3E A;  1KUF A;  2DW0 A;  4GR3 A;  3B92 A;  2DDF A;  1MMQ A;  2HU6 A;  3F15 A;  1GE5 A;  1XUR A;  1USN A;  1QIC A;  1KUH A;  3LGP A;  3BA0 A;  3TVC A;  3NX7 A;  1MMR A;  1Q3A A;  2W13 A;  3DTI A;  4FU4 A;  1XFZ A;  3U1R A;  3DPF A;  5D1U A;  3KEK A;  2USN A;  4IJO A;  3WV1 A;  2FV9 A;  3DL1 A;  3LIR A;  2XS3 A;  1KAP P;  1PWQ A;  2L0R A;  4GF1 A;  4IN9 A;  4XM7 A;  3DWB A;  1XFW A;  2J0T A;  2JT5 A;  3DSL A;  2OXZ A;  1JAP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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