3LGPA

Crystal structure of catalytic domain of tace with benzimidazolyl-thienyl-tartrate based inhibitor
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
257
structure length
251
Chain Sequence
PDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYGGHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Homo sapiens
publication title Structure and activity relationships of tartrate-based TACE inhibitors.
pubmed doi rcsb
molecule keywords Disintegrin and metalloproteinase domain-containing protein
total genus 80
structure length 251
sequence length 257
chains with identical sequence B
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2010-01-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3lgpA00
1YP1A 2USNA 2Z2DA 2QPJA 1UEAA 2L0RA 2DDFA 1IAAA 1JAOA 3EDGA 4EFSA 3E8RA 1AF0A 3KEKA 1CQRA 1XFUA 3LJZA 2AYKA 1ZVXA 2I47A 1ATLA 2JSDA 3DSLA 3K7LA 3EWJA 1PWQA 1JH1A 3LGPA 1G05A 4GUYA 1BUVM 4PKQA 2MZIA 2X3BA 3F15A 3GBOA 1DTHA 1D8FA 3OHOA 3V96B 3TVCA 1MMBA 1JIWP 4DF9A 1BIWA 1GO7P 1XURA 2N8RA 1JAQA 1R55A 1R1HA 1D8MA 3EDHA 1HFSA 1USNA 1A86A 5I2ZA 4ILWD 4PKSA 5D1TA 2CKIA 1UTZA 3HDBA 3P24A 5B5OA 3TSKA 3KEJA 1KUIA 2JIHA 3DPFA 1RM8A 4A7BA 5D3CA 1SLNA 4PKWA 1UTTA 4L19A 3LUNA 3HBUP 2A8HA 3I7IA 1B8YA 1CK7A 1SLMA 3OHLA 4GR8A 2POJA 3RTSA 1G4KA 3N2VA 3HYGA 4AUOA 2OW9A 1JIZA 1BKCA 2FV9A 5I3MA 3LEAA 3ZUKA 1HOVA 5D1SA 2D1OA 3LK8A 4ON1A 2DW0A 4JIJA 1GE6A 1Z3JA 3AIGA 1XFYA 1JAPA 3O2XA 1PWWA 4I35A 2HU6A 4PKVA 1A85A 1FLSA 1Y0VA 2OI0A 3KHIA 2MLSA 2O3EA 5LABA 2OVZA 3LE9A 3HBVP 2OY4A 1B3DA 3VI1A 3LQBA 4L63A 2CLTA 1KUHA 4ZR5A 1XUCA 1HV5A 3LIKA 1BZSA 2W15A 4FU4A 1ZXCA 2DW2A 1QICA 1GKCA 3F18A 2MLRA 4QKZA 4L6TA 1JANA 1KUKA 1H71P 2E2DA 1QUAA 4JA1A 1CGFA 1OMJA 1KBCA 5D2BA 1OM6A 4H30A 3LJGA 5D7WA 1I1IP 2WO8A 1K7GA 4GWMA 3HDAP 1O0TA 3EHXA 5H8XA 456CA 1KAPP 1PWUA 1IACA 1BKCI 1O0QA 3LILA 2PJTA 2X7MA 2XS3A 3KMCA 3Q2HA 4H82A 1G49A 5I4OA 4PKUA 2JT5A 1PWVA 2X3AA 2XS4A 2Y6DA 5B5PA 2MZHA 2OXWA 4GR3A 1SATA 2FV5A 3WV1A 4DPEA 3SHIA 1JJ9A 3N2UA 2O36A 3I7GA 1HTDA 3EDIA 1EUBA 4H49A 1BQOA 1Y93A 2OVXA 3ZVSA 1ROSA 3CKIA 2YIGA 4GF1A 1MMQA 1HY7A 4G9LA 1FBLA 1BSWA 1CGLA 4FXQA 2W13A 4IJOA 3KECA 2W14A 1ASTA 1OM8A 1C7KA 2DDYA 1D5JA 2W12A 1IAEA 3G5CA 5BOYA 1K7QA 1KUGA 2DW1A 1GE5A 4HX3A 1BKCE 1XFVA 4GQLA 1QJJA 3KRYA 4IN9A 4XBHA 2JT6A 3O64A 3WV2A 2ERQA 1BQQM 5D1UA 4CTHA 2V4BA 1C8TA 1XFXA 5I12A 1PWPA 2Y6CA 1IADA 1C3IA 1I76A 1GXDA 2OW0A 3B92A 3TS4A 3TT4A 1Q3AA 2EROA 1ZP5A 3LJTA 2JNPA 4A3WA 5L7FA 1JKYA 3F19A 1GE7A 4JQGA 3L0VA 1BM6A 1QJIA 4DV8A 1IAGA 1I73A 2YB9A 1MMRA 3LUMA 1GO8P 1L6JA 1G12A 1ND1A 4H84A 3KMEA 2J83A 4Q1LA 1SMPA 4FXYP 4G0DA 1EB6A 3HY7A 5I0LA 1GKDA 2OW2A 3KWVC 5CXAA 4AYKA 1KUFA 1G9KA 2RJPA 1S4BP 3DWBA 3F16A 3LMCA 3AYKA 1MMPA 1EAKA 3LIRA 3ELMA 3L0TA 4XM7A 1FM1A 4WZVA 3UVCA 4JPAA 2OZRA 3G42A 5I43A 1OO9A 2SRTA 1R1JA 5JMYA 1BUDA 2OXZA 1MNCA 3BA0A 3AYUA 2X3CA 2TCLA 3EDZA 5CZMA 1OM7A 1SU3A 5L79A 1WNIA 1K7IA 3B8ZA 1AYKA 4GR0A 2AIGP 2ERPA 1CGEA 2W0DA 4FVLA 4WKEA 4WKIA 3USNA 2RJQA 3DNGA 4IUWA 4AXQA 1AKLA 3NX7A 1SRPA 1YOUA 1D7XA 1DMTA 1ZTQA 1R1IA 2K9CA 4WF6A 4GWNA 3VTGA 1CAQA 3DL1A 4PKTA 4PKRA 3LKAA 2K2GA 4H76A 2OXUA 1YCMA 2J0TA 1JK3A 3Q2GA 3DPEA 3RTTA 1CIZA 2E3XA 3EHYA 3HY9A 2D1NA 1RMZA 2KRJA 1J7NA 1YQYA 1R54A 2WO9A 1OS2A 5BPAA 1ZS0A 2WOAA 4DD8A 1XUDA 1UMSA 3F1AA 1UMTA 4I03A 4H3XA 4XM6A 4XM8A 4H2EA 1IABA 5CUHA 3F17A 1XFZA 2OY2A 3ZXHA 1QIBA 3B2ZA 1CXVA 3K7NA 4H1QA 1QIAA 3LQ0A 4R3VA 966CA 3P1VA 4HMAA 4WK7A 2OW1A 5BOTA 1Y8JA 1ZXVA 3HB2P 4J4MA 1XFWA 3WV3A 3MA2A 830CA 3U1RA 1HFCA 1OS9A 2MZEA 4JP4A 4AIGA 4XCTA
chains in the Genus database with same CATH superfamily
1YP1A 2USNA 2Z2DA 2QPJA 1UEAA 2L0RA 2DDFA 1IAAA 1JAOA 3EDGA 4EFSA 3E8RA 1AF0A 3KEKA 1CQRA 1XFUA 3LJZA 2AYKA 1ZVXA 2I47A 1ATLA 2JSDA 3DSLA 3K7LA 3EWJA 1PWQA 1JH1A 3LGPA 1G05A 4GUYA 1BUVM 4PKQA 2MZIA 2X3BA 3F15A 3GBOA 1DTHA 1D8FA 3OHOA 3V96B 3TVCA 1MMBA 1JIWP 4DF9A 1BIWA 1GO7P 1XURA 2N8RA 1JAQA 1R55A 1R1HA 1D8MA 1XAXA 3EDHA 1HFSA 1USNA 1A86A 5I2ZA 4ILWD 4PKSA 5D1TA 2CKIA 1UTZA 3HDBA 3P24A 5B5OA 3TSKA 3KEJA 1KUIA 2JIHA 3DPFA 1RM8A 4A7BA 5D3CA 1SLNA 1XM5A 1UTTA 4PKWA 4L19A 3LUNA 3HBUP 2A8HA 3I7IA 1B8YA 1CK7A 1SLMA 3OHLA 4GR8A 2POJA 3RTSA 1G4KA 3N2VA 3HYGA 4AUOA 2OW9A 1JIZA 1BKCA 2FV9A 5I3MA 3LEAA 3ZUKA 1HOVA 5D1SA 2D1OA 3LK8A 4ON1A 2DW0A 4JIJA 1GE6A 1Z3JA 3AIGA 1XFYA 1JAPA 3O2XA 1PWWA 4I35A 2HU6A 4PKVA 1A85A 1FLSA 1Y0VA 2OI0A 3KHIA 2MLSA 2O3EA 5LABA 2OVZA 3LE9A 3HBVP 2OY4A 1B3DA 3VI1A 3LQBA 4L63A 2CLTA 1KUHA 4ZR5A 1XUCA 1HV5A 3DTIA 3LIKA 1BZSA 2W15A 4FU4A 1ZXCA 2DW2A 1QICA 1GKCA 3F18A 2MLRA 4QKZA 4L6TA 1JANA 1KUKA 1H71P 2E2DA 1QUAA 4JA1A 1CGFA 1OMJA 1KBCA 5D2BA 1OM6A 4H30A 3LJGA 5D7WA 1I1IP 2WO8A 1K7GA 4GWMA 3HDAP 1O0TA 3EHXA 5H8XA 456CA 1KAPP 1PWUA 1IACA 3DTKA 1BKCI 1O0QA 3LILA 2PJTA 2X7MA 2XS3A 3KMCA 3Q2HA 4H82A 1G49A 5I4OA 4PKUA 2JT5A 1PWVA 2X3AA 2XS4A 2Y6DA 5B5PA 2MZHA 2OXWA 4GR3A 1SATA 2FV5A 3WV1A 4DPEA 3SHIA 1JJ9A 3N2UA 2O36A 3I7GA 1HTDA 3EDIA 1EUBA 4H49A 3DTEA 1BQOA 1Y93A 2OVXA 3ZVSA 1ROSA 3CKIA 2YIGA 4GF1A 1MMQA 1HY7A 4G9LA 1FBLA 1BSWA 1CGLA 4FXQA 2W13A 4IJOA 3KECA 2W14A 1ASTA 1OM8A 1C7KA 2DDYA 1D5JA 2W12A 1IAEA 3G5CA 5BOYA 1K7QA 1KUGA 2DW1A 1GE5A 4HX3A 1BKCE 1XFVA 4GQLA 1QJJA 3KRYA 4IN9A 4XBHA 2JT6A 3O64A 3WV2A 2ERQA 1BQQM 5D1UA 4CTHA 2V4BA 1C8TA 1XFXA 5I12A 1PWPA 2Y6CA 1IADA 1C3IA 1I76A 1GXDA 2OW0A 3B92A 3TS4A 3TT4A 1Q3AA 2EROA 1ZP5A 3LJTA 2JNPA 4A3WA 5L7FA 1JKYA 3F19A 1GE7A 4JQGA 3L0VA 1BM6A 1QJIA 4DV8A 1IAGA 1I73A 2YB9A 1MMRA 3LUMA 1GO8P 1L6JA 1G12A 1ND1A 4H84A 3KMEA 2J83A 4Q1LA 1SMPA 4FXYP 4G0DA 1EB6A 3HY7A 5I0LA 1GKDA 2OW2A 3KWVC 5CXAA 4AYKA 1KUFA 1G9KA 2RJPA 1S4BP 3DWBA 3F16A 3LMCA 3AYKA 1MMPA 1EAKA 2YUFA 3LIRA 3ELMA 3L0TA 4XM7A 1FM1A 4WZVA 3UVCA 4JPAA 2OZRA 3G42A 5I43A 1OO9A 2SRTA 1R1JA 5JMYA 1BUDA 2OXZA 1MNCA 3BA0A 3AYUA 2X3CA 2TCLA 3EDZA 5CZMA 1OM7A 1SU3A 5L79A 1WNIA 1K7IA 3B8ZA 1AYKA 4GR0A 2AIGP 2ERPA 1CGEA 2W0DA 4FVLA 4WKEA 4WKIA 3USNA 2RJQA 3DNGA 4IUWA 4AXQA 1AKLA 3NX7A 1SRPA 1YOUA 1D7XA 1DMTA 1ZTQA 1R1IA 2K9CA 4WF6A 4GWNA 3VTGA 1CAQA 3DL1A 4PKTA 4PKRA 3LKAA 2K2GA 4H76A 2OXUA 1YCMA 2J0TA 1JK3A 3Q2GA 3DPEA 3RTTA 1CIZA 2E3XA 3EHYA 3HY9A 2D1NA 1RMZA 2KRJA 1J7NA 1YQYA 1R54A 2WO9A 1OS2A 4L7AA 5BPAA 1ZS0A 2WOAA 4DD8A 1XUDA 1OZ9A 1UMSA 3F1AA 1UMTA 4I03A 4H3XA 4XM6A 4XM8A 4H2EA 1IABA 5CUHA 3F17A 1XFZA 2OY2A 3ZXHA 1QIBA 1TVIA 3B2ZA 1CXVA 3K7NA 4H1QA 1QIAA 3LQ0A 4R3VA 966CA 3P1VA 4HMAA 4WK7A 2OW1A 5BOTA 1Y8JA 1ZXVA 3HB2P 4J4MA 1XFWA 3WV3A 3MA2A 830CA 3U1RA 1HFCA 1OS9A 2MZEA 4JP4A 4AIGA 4XCTA
chains in the Genus database with same CATH topology
1YP1A 2USNA 2Z2DA 2QPJA 1UEAA 2L0RA 2DDFA 1IAAA 1JAOA 3EDGA 4EFSA 3E8RA 1AF0A 3KEKA 1CQRA 1XFUA 3LJZA 2AYKA 1ZVXA 2I47A 1ATLA 2JSDA 3DSLA 3K7LA 3EWJA 1PWQA 1JH1A 3LGPA 1G05A 4GUYA 1BUVM 4PKQA 2MZIA 2X3BA 3F15A 3GBOA 1DTHA 1D8FA 3OHOA 3V96B 3TVCA 1MMBA 1JIWP 4DF9A 1BIWA 1GO7P 1XURA 2N8RA 1JAQA 1R55A 1R1HA 1D8MA 3EDHA 1HFSA 1USNA 1A86A 5I2ZA 4ILWD 4PKSA 5D1TA 2CKIA 1UTZA 3HDBA 3P24A 5B5OA 3TSKA 3KEJA 1KUIA 2JIHA 3DPFA 1RM8A 4A7BA 5D3CA 1SLNA 4PKWA 1UTTA 4L19A 3LUNA 3HBUP 2A8HA 3I7IA 1B8YA 1CK7A 1SLMA 3OHLA 4GR8A 2POJA 3RTSA 1G4KA 3N2VA 3HYGA 4AUOA 2OW9A 1JIZA 1BKCA 2FV9A 5I3MA 3LEAA 3ZUKA 1HOVA 5D1SA 2D1OA 3LK8A 4ON1A 2DW0A 4JIJA 1GE6A 1Z3JA 3AIGA 1XFYA 1JAPA 3O2XA 1PWWA 4I35A 2HU6A 4PKVA 1A85A 1FLSA 1Y0VA 2OI0A 3KHIA 2MLSA 2O3EA 5LABA 2OVZA 3LE9A 3HBVP 2OY4A 1B3DA 3VI1A 3LQBA 4L63A 2CLTA 1KUHA 4ZR5A 1XUCA 1HV5A 3DTIA 3LIKA 1BZSA 2W15A 4FU4A 1ZXCA 2DW2A 1QICA 1GKCA 3F18A 2MLRA 4QKZA 4L6TA 1JANA 1KUKA 1H71P 2E2DA 1QUAA 4JA1A 1CGFA 1OMJA 1KBCA 5D2BA 1OM6A 4H30A 3LJGA 5D7WA 1I1IP 2WO8A 1K7GA 4GWMA 3HDAP 1O0TA 3EHXA 5H8XA 456CA 1KAPP 1PWUA 1IACA 3DTKA 1BKCI 1O0QA 3LILA 2PJTA 2X7MA 2XS3A 3KMCA 3Q2HA 4H82A 1G49A 5I4OA 4PKUA 2JT5A 1PWVA 2X3AA 2XS4A 2Y6DA 5B5PA 2MZHA 2OXWA 4GR3A 1SATA 2FV5A 3WV1A 4DPEA 3SHIA 1JJ9A 3N2UA 2O36A 3I7GA 1HTDA 3EDIA 1EUBA 4H49A 3DTEA 1BQOA 1Y93A 2OVXA 3ZVSA 1ROSA 3CKIA 2YIGA 4GF1A 1MMQA 1HY7A 4G9LA 1FBLA 1BSWA 1CGLA 4FXQA 2W13A 4IJOA 3KECA 2W14A 1ASTA 1OM8A 1C7KA 2DDYA 1D5JA 2W12A 1IAEA 3G5CA 5BOYA 1K7QA 1KUGA 2DW1A 1GE5A 4HX3A 1BKCE 1XFVA 4GQLA 1QJJA 3KRYA 4IN9A 4XBHA 2JT6A 3O64A 3WV2A 2ERQA 1BQQM 5D1UA 4CTHA 2V4BA 1C8TA 1XFXA 5I12A 1PWPA 2Y6CA 1IADA 1C3IA 1I76A 1GXDA 2OW0A 3B92A 3TS4A 3TT4A 1Q3AA 2EROA 1ZP5A 3LJTA 2JNPA 4A3WA 5L7FA 1JKYA 3F19A 1GE7A 4JQGA 3L0VA 1BM6A 1QJIA 4DV8A 1IAGA 1I73A 2YB9A 1MMRA 3LUMA 1GO8P 1L6JA 1G12A 1ND1A 4H84A 3KMEA 2J83A 4Q1LA 1SMPA 4FXYP 4G0DA 1EB6A 3HY7A 5I0LA 1GKDA 2OW2A 3KWVC 5CXAA 4AYKA 1KUFA 1G9KA 2RJPA 1S4BP 3DWBA 3F16A 3LMCA 3AYKA 1MMPA 1EAKA 2YUFA 3LIRA 3ELMA 3L0TA 4XM7A 1FM1A 4WZVA 3UVCA 4JPAA 2OZRA 3G42A 5I43A 1OO9A 2SRTA 1R1JA 5JMYA 1BUDA 2OXZA 1MNCA 3BA0A 3AYUA 2X3CA 2TCLA 3EDZA 5CZMA 1OM7A 1SU3A 5L79A 1WNIA 1K7IA 3B8ZA 1AYKA 4GR0A 2AIGP 2ERPA 1CGEA 2W0DA 4FVLA 4WKEA 4WKIA 3USNA 2RJQA 3DNGA 4IUWA 4AXQA 1AKLA 3NX7A 1SRPA 1YOUA 1D7XA 1DMTA 1ZTQA 1R1IA 2K9CA 4WF6A 4GWNA 3VTGA 1CAQA 3DL1A 4PKTA 4PKRA 3LKAA 2K2GA 4H76A 2OXUA 1YCMA 2J0TA 1JK3A 3Q2GA 3DPEA 3RTTA 1CIZA 2E3XA 3EHYA 3HY9A 2D1NA 1RMZA 2KRJA 1J7NA 1YQYA 1R54A 2WO9A 1OS2A 4L7AA 5BPAA 1ZS0A 2WOAA 4DD8A 1XUDA 1UMSA 3F1AA 1UMTA 4I03A 4H3XA 4XM6A 4XM8A 4H2EA 1IABA 5CUHA 3F17A 1XFZA 2OY2A 3ZXHA 1QIBA 3B2ZA 1CXVA 3K7NA 4H1QA 1QIAA 3LQ0A 4R3VA 966CA 3P1VA 4HMAA 4WK7A 2OW1A 5BOTA 1Y8JA 1ZXVA 3HB2P 4J4MA 1XFWA 3WV3A 3MA2A 830CA 3U1RA 1HFCA 1OS9A 2MZEA 4JP4A 4AIGA 4XCTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YP1 A;  2USN A;  2Z2D A;  2QPJ A;  1UEA A;  2L0R A;  2DDF A;  1IAA A;  1JAO A;  3EDG A;  4EFS A;  3E8R A;  1AF0 A;  3KEK A;  1CQR A;  1XFU A;  3LJZ A;  2AYK A;  1ZVX A;  2I47 A;  1ATL A;  2JSD A;  3DSL A;  3K7L A;  3EWJ A;  1PWQ A;  1JH1 A;  3LGP A;  1G05 A;  4GUY A;  1BUV M;  4PKQ A;  2MZI A;  2X3B A;  3F15 A;  3GBO A;  1DTH A;  1D8F A;  3OHO A;  3V96 B;  3TVC A;  1MMB A;  1JIW P;  4DF9 A;  1BIW A;  1GO7 P;  1XUR A;  2N8R A;  1JAQ A;  1R55 A;  1R1H A;  1D8M A;  3EDH A;  1HFS A;  1USN A;  1A86 A;  5I2Z A;  4ILW D;  4PKS A;  5D1T A;  2CKI A;  1UTZ A;  3HDB A;  3P24 A;  5B5O A;  3TSK A;  3KEJ A;  1KUI A;  2JIH A;  3DPF A;  1RM8 A;  4A7B A;  5D3C A;  1SLN A;  4PKW A;  1UTT A;  4L19 A;  3LUN A;  3HBU P;  2A8H A;  3I7I A;  1B8Y A;  1CK7 A;  1SLM A;  3OHL A;  4GR8 A;  2POJ A;  3RTS A;  1G4K A;  3N2V A;  3HYG A;  4AUO A;  2OW9 A;  1JIZ A;  1BKC A;  2FV9 A;  5I3M A;  3LEA A;  3ZUK A;  1HOV A;  5D1S A;  2D1O A;  3LK8 A;  4ON1 A;  2DW0 A;  4JIJ A;  1GE6 A;  1Z3J A;  3AIG A;  1XFY A;  1JAP A;  3O2X A;  1PWW A;  4I35 A;  2HU6 A;  4PKV A;  1A85 A;  1FLS A;  1Y0V A;  2OI0 A;  3KHI A;  2MLS A;  2O3E A;  5LAB A;  2OVZ A;  3LE9 A;  3HBV P;  2OY4 A;  1B3D A;  3VI1 A;  3LQB A;  4L63 A;  2CLT A;  1KUH A;  4ZR5 A;  1XUC A;  1HV5 A;  3LIK A;  1BZS A;  2W15 A;  4FU4 A;  1ZXC A;  2DW2 A;  1QIC A;  1GKC A;  3F18 A;  2MLR A;  4QKZ A;  4L6T A;  1JAN A;  1KUK A;  1H71 P;  2E2D A;  1QUA A;  4JA1 A;  1CGF A;  1OMJ A;  1KBC A;  5D2B A;  1OM6 A;  4H30 A;  3LJG A;  5D7W A;  1I1I P;  2WO8 A;  1K7G A;  4GWM A;  3HDA P;  1O0T A;  3EHX A;  5H8X A;  456C A;  1KAP P;  1PWU A;  1IAC A;  1BKC I;  1O0Q A;  3LIL A;  2PJT A;  2X7M A;  2XS3 A;  3KMC A;  3Q2H A;  4H82 A;  1G49 A;  5I4O A;  4PKU A;  2JT5 A;  1PWV A;  2X3A A;  2XS4 A;  2Y6D A;  5B5P A;  2MZH A;  2OXW A;  4GR3 A;  1SAT A;  2FV5 A;  3WV1 A;  4DPE A;  3SHI A;  1JJ9 A;  3N2U A;  2O36 A;  3I7G A;  1HTD A;  3EDI A;  1EUB A;  4H49 A;  1BQO A;  1Y93 A;  2OVX A;  3ZVS A;  1ROS A;  3CKI A;  2YIG A;  4GF1 A;  1MMQ A;  1HY7 A;  4G9L A;  1FBL A;  1BSW A;  1CGL A;  4FXQ A;  2W13 A;  4IJO A;  3KEC A;  2W14 A;  1AST A;  1OM8 A;  1C7K A;  2DDY A;  1D5J A;  2W12 A;  1IAE A;  3G5C A;  5BOY A;  1K7Q A;  1KUG A;  2DW1 A;  1GE5 A;  4HX3 A;  1BKC E;  1XFV A;  4GQL A;  1QJJ A;  3KRY A;  4IN9 A;  4XBH A;  2JT6 A;  3O64 A;  3WV2 A;  2ERQ A;  1BQQ M;  5D1U A;  4CTH A;  2V4B A;  1C8T A;  1XFX A;  5I12 A;  1PWP A;  2Y6C A;  1IAD A;  1C3I A;  1I76 A;  1GXD A;  2OW0 A;  3B92 A;  3TS4 A;  3TT4 A;  1Q3A A;  2ERO A;  1ZP5 A;  3LJT A;  2JNP A;  4A3W A;  5L7F A;  1JKY A;  3F19 A;  1GE7 A;  4JQG A;  3L0V A;  1BM6 A;  1QJI A;  4DV8 A;  1IAG A;  1I73 A;  2YB9 A;  1MMR A;  3LUM A;  1GO8 P;  1L6J A;  1G12 A;  1ND1 A;  4H84 A;  3KME A;  2J83 A;  4Q1L A;  1SMP A;  4FXY P;  4G0D A;  1EB6 A;  3HY7 A;  5I0L A;  1GKD A;  2OW2 A;  3KWV C;  5CXA A;  4AYK A;  1KUF A;  1G9K A;  2RJP A;  1S4B P;  3DWB A;  3F16 A;  3LMC A;  3AYK A;  1MMP A;  1EAK A;  3LIR A;  3ELM A;  3L0T A;  4XM7 A;  1FM1 A;  4WZV A;  3UVC A;  4JPA A;  2OZR A;  3G42 A;  5I43 A;  1OO9 A;  2SRT A;  1R1J A;  5JMY A;  1BUD A;  2OXZ A;  1MNC A;  3BA0 A;  3AYU A;  2X3C A;  2TCL A;  3EDZ A;  5CZM A;  1OM7 A;  1SU3 A;  5L79 A;  1WNI A;  1K7I A;  3B8Z A;  1AYK A;  4GR0 A;  2AIG P;  2ERP A;  1CGE A;  2W0D A;  4FVL A;  4WKE A;  4WKI A;  3USN A;  2RJQ A;  3DNG A;  4IUW A;  4AXQ A;  1AKL A;  3NX7 A;  1SRP A;  1YOU A;  1D7X A;  1DMT A;  1ZTQ A;  1R1I A;  2K9C A;  4WF6 A;  4GWN A;  3VTG A;  1CAQ A;  3DL1 A;  4PKT A;  4PKR A;  3LKA A;  2K2G A;  4H76 A;  2OXU A;  1YCM A;  2J0T A;  1JK3 A;  3Q2G A;  3DPE A;  3RTT A;  1CIZ A;  2E3X A;  3EHY A;  3HY9 A;  2D1N A;  1RMZ A;  2KRJ A;  1J7N A;  1YQY A;  1R54 A;  2WO9 A;  1OS2 A;  5BPA A;  1ZS0 A;  2WOA A;  4DD8 A;  1XUD A;  1UMS A;  3F1A A;  1UMT A;  4I03 A;  4H3X A;  4XM6 A;  4XM8 A;  4H2E A;  1IAB A;  5CUH A;  3F17 A;  1XFZ A;  2OY2 A;  3ZXH A;  1QIB A;  3B2Z A;  1CXV A;  3K7N A;  4H1Q A;  1QIA A;  3LQ0 A;  4R3V A;  966C A;  3P1V A;  4HMA A;  4WK7 A;  2OW1 A;  5BOT A;  1Y8J A;  1ZXV A;  3HB2 P;  4J4M A;  1XFW A;  3WV3 A;  3MA2 A;  830C A;  3U1R A;  1HFC A;  1OS9 A;  2MZE A;  4JP4 A;  4AIG A;  4XCT A; 
#chains in the Genus database with same CATH topology
 1YP1 A;  2USN A;  2Z2D A;  2QPJ A;  1UEA A;  2L0R A;  2DDF A;  1IAA A;  1JAO A;  3EDG A;  4EFS A;  3E8R A;  1AF0 A;  3KEK A;  1CQR A;  1XFU A;  3LJZ A;  2AYK A;  1ZVX A;  2I47 A;  1ATL A;  2JSD A;  3DSL A;  3K7L A;  3EWJ A;  1PWQ A;  1JH1 A;  3LGP A;  1G05 A;  4GUY A;  1BUV M;  4PKQ A;  2MZI A;  2X3B A;  3F15 A;  3GBO A;  1DTH A;  1D8F A;  3OHO A;  3V96 B;  3TVC A;  1MMB A;  1JIW P;  4DF9 A;  1BIW A;  1GO7 P;  1XUR A;  2N8R A;  1JAQ A;  1R55 A;  1R1H A;  1D8M A;  1XAX A;  3EDH A;  1HFS A;  1USN A;  1A86 A;  5I2Z A;  4ILW D;  4PKS A;  5D1T A;  2CKI A;  1UTZ A;  3HDB A;  3P24 A;  5B5O A;  3TSK A;  3KEJ A;  1KUI A;  2JIH A;  3DPF A;  1RM8 A;  4A7B A;  5D3C A;  1SLN A;  1XM5 A;  1UTT A;  4PKW A;  4L19 A;  3LUN A;  3HBU P;  2A8H A;  3I7I A;  1B8Y A;  1CK7 A;  1SLM A;  3OHL A;  4GR8 A;  2POJ A;  3RTS A;  1G4K A;  3N2V A;  3HYG A;  4AUO A;  2OW9 A;  1JIZ A;  1BKC A;  2FV9 A;  5I3M A;  3LEA A;  3ZUK A;  1HOV A;  5D1S A;  2D1O A;  3LK8 A;  4ON1 A;  2DW0 A;  4JIJ A;  1GE6 A;  1Z3J A;  3AIG A;  1XFY A;  1JAP A;  3O2X A;  1PWW A;  4I35 A;  2HU6 A;  4PKV A;  1A85 A;  1FLS A;  1Y0V A;  2OI0 A;  3KHI A;  2MLS A;  2O3E A;  5LAB A;  2OVZ A;  3LE9 A;  3HBV P;  2OY4 A;  1B3D A;  3VI1 A;  3LQB A;  4L63 A;  2CLT A;  1KUH A;  4ZR5 A;  1XUC A;  1HV5 A;  3DTI A;  3LIK A;  1BZS A;  2W15 A;  4FU4 A;  1ZXC A;  2DW2 A;  1QIC A;  1GKC A;  3F18 A;  2MLR A;  4QKZ A;  4L6T A;  1JAN A;  1KUK A;  1H71 P;  2E2D A;  1QUA A;  4JA1 A;  1CGF A;  1OMJ A;  1KBC A;  5D2B A;  1OM6 A;  4H30 A;  3LJG A;  5D7W A;  1I1I P;  2WO8 A;  1K7G A;  4GWM A;  3HDA P;  1O0T A;  3EHX A;  5H8X A;  456C A;  1KAP P;  1PWU A;  1IAC A;  3DTK A;  1BKC I;  1O0Q A;  3LIL A;  2PJT A;  2X7M A;  2XS3 A;  3KMC A;  3Q2H A;  4H82 A;  1G49 A;  5I4O A;  4PKU A;  2JT5 A;  1PWV A;  2X3A A;  2XS4 A;  2Y6D A;  5B5P A;  2MZH A;  2OXW A;  4GR3 A;  1SAT A;  2FV5 A;  3WV1 A;  4DPE A;  3SHI A;  1JJ9 A;  3N2U A;  2O36 A;  3I7G A;  1HTD A;  3EDI A;  1EUB A;  4H49 A;  3DTE A;  1BQO A;  1Y93 A;  2OVX A;  3ZVS A;  1ROS A;  3CKI A;  2YIG A;  4GF1 A;  1MMQ A;  1HY7 A;  4G9L A;  1FBL A;  1BSW A;  1CGL A;  4FXQ A;  2W13 A;  4IJO A;  3KEC A;  2W14 A;  1AST A;  1OM8 A;  1C7K A;  2DDY A;  1D5J A;  2W12 A;  1IAE A;  3G5C A;  5BOY A;  1K7Q A;  1KUG A;  2DW1 A;  1GE5 A;  4HX3 A;  1BKC E;  1XFV A;  4GQL A;  1QJJ A;  3KRY A;  4IN9 A;  4XBH A;  2JT6 A;  3O64 A;  3WV2 A;  2ERQ A;  1BQQ M;  5D1U A;  4CTH A;  2V4B A;  1C8T A;  1XFX A;  5I12 A;  1PWP A;  2Y6C A;  1IAD A;  1C3I A;  1I76 A;  1GXD A;  2OW0 A;  3B92 A;  3TS4 A;  3TT4 A;  1Q3A A;  2ERO A;  1ZP5 A;  3LJT A;  2JNP A;  4A3W A;  5L7F A;  1JKY A;  3F19 A;  1GE7 A;  4JQG A;  3L0V A;  1BM6 A;  1QJI A;  4DV8 A;  1IAG A;  1I73 A;  2YB9 A;  1MMR A;  3LUM A;  1GO8 P;  1L6J A;  1G12 A;  1ND1 A;  4H84 A;  3KME A;  2J83 A;  4Q1L A;  1SMP A;  4FXY P;  4G0D A;  1EB6 A;  3HY7 A;  5I0L A;  1GKD A;  2OW2 A;  3KWV C;  5CXA A;  4AYK A;  1KUF A;  1G9K A;  2RJP A;  1S4B P;  3DWB A;  3F16 A;  3LMC A;  3AYK A;  1MMP A;  1EAK A;  2YUF A;  3LIR A;  3ELM A;  3L0T A;  4XM7 A;  1FM1 A;  4WZV A;  3UVC A;  4JPA A;  2OZR A;  3G42 A;  5I43 A;  1OO9 A;  2SRT A;  1R1J A;  5JMY A;  1BUD A;  2OXZ A;  1MNC A;  3BA0 A;  3AYU A;  2X3C A;  2TCL A;  3EDZ A;  5CZM A;  1OM7 A;  1SU3 A;  5L79 A;  1WNI A;  1K7I A;  3B8Z A;  1AYK A;  4GR0 A;  2AIG P;  2ERP A;  1CGE A;  2W0D A;  4FVL A;  4WKE A;  4WKI A;  3USN A;  2RJQ A;  3DNG A;  4IUW A;  4AXQ A;  1AKL A;  3NX7 A;  1SRP A;  1YOU A;  1D7X A;  1DMT A;  1ZTQ A;  1R1I A;  2K9C A;  4WF6 A;  4GWN A;  3VTG A;  1CAQ A;  3DL1 A;  4PKT A;  4PKR A;  3LKA A;  2K2G A;  4H76 A;  2OXU A;  1YCM A;  2J0T A;  1JK3 A;  3Q2G A;  3DPE A;  3RTT A;  1CIZ A;  2E3X A;  3EHY A;  3HY9 A;  2D1N A;  1RMZ A;  2KRJ A;  1J7N A;  1YQY A;  1R54 A;  2WO9 A;  1OS2 A;  4L7A A;  5BPA A;  1ZS0 A;  2WOA A;  4DD8 A;  1XUD A;  1OZ9 A;  1UMS A;  3F1A A;  1UMT A;  4I03 A;  4H3X A;  4XM6 A;  4XM8 A;  4H2E A;  1IAB A;  5CUH A;  3F17 A;  1XFZ A;  2OY2 A;  3ZXH A;  1QIB A;  1TVI A;  3B2Z A;  1CXV A;  3K7N A;  4H1Q A;  1QIA A;  3LQ0 A;  4R3V A;  966C A;  3P1V A;  4HMA A;  4WK7 A;  2OW1 A;  5BOT A;  1Y8J A;  1ZXV A;  3HB2 P;  4J4M A;  1XFW A;  3WV3 A;  3MA2 A;  830C A;  3U1R A;  1HFC A;  1OS9 A;  2MZE A;  4JP4 A;  4AIG A;  4XCT A; 
#chains in the Genus database with same CATH homology
 1YP1 A;  2USN A;  2Z2D A;  2QPJ A;  1UEA A;  2L0R A;  2DDF A;  1IAA A;  1JAO A;  3EDG A;  4EFS A;  3E8R A;  1AF0 A;  3KEK A;  1CQR A;  1XFU A;  3LJZ A;  2AYK A;  1ZVX A;  2I47 A;  1ATL A;  2JSD A;  3DSL A;  3K7L A;  3EWJ A;  1PWQ A;  1JH1 A;  3LGP A;  1G05 A;  4GUY A;  1BUV M;  4PKQ A;  2MZI A;  2X3B A;  3F15 A;  3GBO A;  1DTH A;  1D8F A;  3OHO A;  3V96 B;  3TVC A;  1MMB A;  1JIW P;  4DF9 A;  1BIW A;  1GO7 P;  1XUR A;  2N8R A;  1JAQ A;  1R55 A;  1R1H A;  1D8M A;  3EDH A;  1HFS A;  1USN A;  1A86 A;  5I2Z A;  4ILW D;  4PKS A;  5D1T A;  2CKI A;  1UTZ A;  3HDB A;  3P24 A;  5B5O A;  3TSK A;  3KEJ A;  1KUI A;  2JIH A;  3DPF A;  1RM8 A;  4A7B A;  5D3C A;  1SLN A;  4PKW A;  1UTT A;  4L19 A;  3LUN A;  3HBU P;  2A8H A;  3I7I A;  1B8Y A;  1CK7 A;  1SLM A;  3OHL A;  4GR8 A;  2POJ A;  3RTS A;  1G4K A;  3N2V A;  3HYG A;  4AUO A;  2OW9 A;  1JIZ A;  1BKC A;  2FV9 A;  5I3M A;  3LEA A;  3ZUK A;  1HOV A;  5D1S A;  2D1O A;  3LK8 A;  4ON1 A;  2DW0 A;  4JIJ A;  1GE6 A;  1Z3J A;  3AIG A;  1XFY A;  1JAP A;  3O2X A;  1PWW A;  4I35 A;  2HU6 A;  4PKV A;  1A85 A;  1FLS A;  1Y0V A;  2OI0 A;  3KHI A;  2MLS A;  2O3E A;  5LAB A;  2OVZ A;  3LE9 A;  3HBV P;  2OY4 A;  1B3D A;  3VI1 A;  3LQB A;  4L63 A;  2CLT A;  1KUH A;  4ZR5 A;  1XUC A;  1HV5 A;  3DTI A;  3LIK A;  1BZS A;  2W15 A;  4FU4 A;  1ZXC A;  2DW2 A;  1QIC A;  1GKC A;  3F18 A;  2MLR A;  4QKZ A;  4L6T A;  1JAN A;  1KUK A;  1H71 P;  2E2D A;  1QUA A;  4JA1 A;  1CGF A;  1OMJ A;  1KBC A;  5D2B A;  1OM6 A;  4H30 A;  3LJG A;  5D7W A;  1I1I P;  2WO8 A;  1K7G A;  4GWM A;  3HDA P;  1O0T A;  3EHX A;  5H8X A;  456C A;  1KAP P;  1PWU A;  1IAC A;  3DTK A;  1BKC I;  1O0Q A;  3LIL A;  2PJT A;  2X7M A;  2XS3 A;  3KMC A;  3Q2H A;  4H82 A;  1G49 A;  5I4O A;  4PKU A;  2JT5 A;  1PWV A;  2X3A A;  2XS4 A;  2Y6D A;  5B5P A;  2MZH A;  2OXW A;  4GR3 A;  1SAT A;  2FV5 A;  3WV1 A;  4DPE A;  3SHI A;  1JJ9 A;  3N2U A;  2O36 A;  3I7G A;  1HTD A;  3EDI A;  1EUB A;  4H49 A;  3DTE A;  1BQO A;  1Y93 A;  2OVX A;  3ZVS A;  1ROS A;  3CKI A;  2YIG A;  4GF1 A;  1MMQ A;  1HY7 A;  4G9L A;  1FBL A;  1BSW A;  1CGL A;  4FXQ A;  2W13 A;  4IJO A;  3KEC A;  2W14 A;  1AST A;  1OM8 A;  1C7K A;  2DDY A;  1D5J A;  2W12 A;  1IAE A;  3G5C A;  5BOY A;  1K7Q A;  1KUG A;  2DW1 A;  1GE5 A;  4HX3 A;  1BKC E;  1XFV A;  4GQL A;  1QJJ A;  3KRY A;  4IN9 A;  4XBH A;  2JT6 A;  3O64 A;  3WV2 A;  2ERQ A;  1BQQ M;  5D1U A;  4CTH A;  2V4B A;  1C8T A;  1XFX A;  5I12 A;  1PWP A;  2Y6C A;  1IAD A;  1C3I A;  1I76 A;  1GXD A;  2OW0 A;  3B92 A;  3TS4 A;  3TT4 A;  1Q3A A;  2ERO A;  1ZP5 A;  3LJT A;  2JNP A;  4A3W A;  5L7F A;  1JKY A;  3F19 A;  1GE7 A;  4JQG A;  3L0V A;  1BM6 A;  1QJI A;  4DV8 A;  1IAG A;  1I73 A;  2YB9 A;  1MMR A;  3LUM A;  1GO8 P;  1L6J A;  1G12 A;  1ND1 A;  4H84 A;  3KME A;  2J83 A;  4Q1L A;  1SMP A;  4FXY P;  4G0D A;  1EB6 A;  3HY7 A;  5I0L A;  1GKD A;  2OW2 A;  3KWV C;  5CXA A;  4AYK A;  1KUF A;  1G9K A;  2RJP A;  1S4B P;  3DWB A;  3F16 A;  3LMC A;  3AYK A;  1MMP A;  1EAK A;  2YUF A;  3LIR A;  3ELM A;  3L0T A;  4XM7 A;  1FM1 A;  4WZV A;  3UVC A;  4JPA A;  2OZR A;  3G42 A;  5I43 A;  1OO9 A;  2SRT A;  1R1J A;  5JMY A;  1BUD A;  2OXZ A;  1MNC A;  3BA0 A;  3AYU A;  2X3C A;  2TCL A;  3EDZ A;  5CZM A;  1OM7 A;  1SU3 A;  5L79 A;  1WNI A;  1K7I A;  3B8Z A;  1AYK A;  4GR0 A;  2AIG P;  2ERP A;  1CGE A;  2W0D A;  4FVL A;  4WKE A;  4WKI A;  3USN A;  2RJQ A;  3DNG A;  4IUW A;  4AXQ A;  1AKL A;  3NX7 A;  1SRP A;  1YOU A;  1D7X A;  1DMT A;  1ZTQ A;  1R1I A;  2K9C A;  4WF6 A;  4GWN A;  3VTG A;  1CAQ A;  3DL1 A;  4PKT A;  4PKR A;  3LKA A;  2K2G A;  4H76 A;  2OXU A;  1YCM A;  2J0T A;  1JK3 A;  3Q2G A;  3DPE A;  3RTT A;  1CIZ A;  2E3X A;  3EHY A;  3HY9 A;  2D1N A;  1RMZ A;  2KRJ A;  1J7N A;  1YQY A;  1R54 A;  2WO9 A;  1OS2 A;  4L7A A;  5BPA A;  1ZS0 A;  2WOA A;  4DD8 A;  1XUD A;  1UMS A;  3F1A A;  1UMT A;  4I03 A;  4H3X A;  4XM6 A;  4XM8 A;  4H2E A;  1IAB A;  5CUH A;  3F17 A;  1XFZ A;  2OY2 A;  3ZXH A;  1QIB A;  3B2Z A;  1CXV A;  3K7N A;  4H1Q A;  1QIA A;  3LQ0 A;  4R3V A;  966C A;  3P1V A;  4HMA A;  4WK7 A;  2OW1 A;  5BOT A;  1Y8J A;  1ZXV A;  3HB2 P;  4J4M A;  1XFW A;  3WV3 A;  3MA2 A;  830C A;  3U1R A;  1HFC A;  1OS9 A;  2MZE A;  4JP4 A;  4AIG A;  4XCT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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