3LIKA

Human mmp12 in complex with non-zinc chelating inhibitor
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
159
structure length
159
Chain Sequence
MGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Insights from selective non-phosphinic inhibitors of MMP-12 tailored to fit with an S1' loop canonical conformation.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Macrophage metalloelastase
total genus 44
structure length 159
sequence length 159
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2010-01-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3likA00
1ZVXA 1L6JA 456CA 1CAQA 3O2XA 4FXYP 4DPEA 3HBUP 2W14A 4WZVA 1KUHA 1JKYA 3F16A 1Y93A 3ZVSA 4HMAA 4GR3A 2OZRA 1GKDA 3KMCA 3LGPA 3O64A 4GUYA 4GWNA 3ELMA 1JAOA 2CLTA 4J4MA 3ZXHA 1PWWA 1OS2A 1A85A 5CUHA 3G5CA 3K7NA 3AYUA 4AYKA 1C8TA 1SATA 1FLSA 3LIKA 1MNCA 1JIWP 1YQYA 2AYKA 1BUDA 5D7WA 2TCLA 1BKCA 2WO9A 4HX3A 1ZXCA 3P24A 1AKLA 3EHXA 1B3DA 2MZEA 3B2ZA 1QUAA 4WK7A 3KHIA 3KMEA 5I43A 1HFCA 2SRTA 3MA2A 4G9LA 2Y6CA 4JQGA 1XFXA 1G49A 5D1SA 4JPAA 3LQ0A 3K7LA 3Q2HA 2J83A 3G42A 2OVZA 3EDIA 2OI0A 1DTHA 3HDAP 966CA 2K9CA 4WKIA 2X3AA 1S4BP 2W15A 4H2EA 2DW1A 3KWVC 3L0TA 4IUWA 3VI1A 1JIZA 2OVXA 1J7NA 3F19A 2X7MA 3WV2A 1IAAA 2XS4A 2OW1A 1D5JA 1ROSA 1BKCI 1GE7A 2HU6A 3TS4A 1IAGA 3DL1A 4DF9A 3EDGA 1UTTA 1I76A 2Y6DA 1BM6A 1IAEA 3HY9A 4H82A 3USNA 3RTSA 4Q1LA 1AF0A 3EHYA 1PWQA 1SMPA 1BIWA 4JA1A 3LEAA 2MZHA 3I7GA 3VTGA 1R1JA 2MLRA 1XURA 2O3EA 5H8XA 3CKIA 1BQOA 1GO7P 3HBVP 1ASTA 2POJA 3LJTA 2WO8A 1SLMA 3P1VA 3UVCA 2E3XA 4GQLA 1JAPA 1JJ9A 2EROA 3SHIA 1WNIA 4QKZA 1YCMA 3LUNA 1OM8A 1OMJA 4GWMA 4XCTA 1BZSA 1C7KA 1QICA 2W0DA 1JAQA 5D1UA 5L7FA 1I1IP 3HY7A 5I0LA 2DW2A 3N2UA 1R54A 4G0DA 3HYGA 4H3XA 4WKEA 1RM8A 2FV9A 2OW2A 1Y0VA 3LK8A 4PKVA 5I4OA 3B8ZA 4AXQA 5JMYA 4IJOA 1G05A 3DWBA 1GE6A 2JT6A 4PKUA 3WV1A 1I73A 3DSLA 3KRYA 4ZR5A 1KUGA 1YP1A 5L79A 1O0QA 3F1AA 4A7BA 5LABA 4IN9A 1Q3AA 2JIHA 1XFYA 2JNPA 2E2DA 4I03A 4L6TA 5CZMA 1CGFA 1EUBA 2OW9A 3V96B 1OM6A 2XS3A 1BQQM 4FU4A 1SU3A 4PKWA 1GE5A 5I12A 1SLNA 3TVCA 1MMBA 1EB6A 1KUIA 4PKRA 1AYKA 2MLSA 2YIGA 830CA 3ZUKA 2ERQA 2N8RA 2D1NA 3EDZA 1IABA 1DMTA 2I47A 1CK7A 3OHLA 3KEJA 1HY7A 1PWPA 2OW0A 1YOUA 1RMZA 4GF1A 3LUMA 1R1HA 3LJZA 1XFUA 2RJQA 2D1OA 1BSWA 4CTHA 5BOYA 3DNGA 4AIGA 2AIGP 2CKIA 1HTDA 1OM7A 1G12A 1H71P 2O36A 1CGLA 2RJPA 2OY2A 1CQRA 1B8YA 2V4BA 2K2GA 2QPJA 2X3BA 3LJGA 3OHOA 2W13A 4XBHA 1ND1A 5I3MA 3LILA 4XM8A 3LKAA 1R1IA 2DDFA 4H76A 1K7QA 4JIJA 3WV3A 5D1TA 2YB9A 1CXVA 1XUCA 1ATLA 1FBLA 3KECA 1Z3JA 4A3WA 4L19A 2PJTA 4H1QA 1QIAA 1CIZA 1QJIA 3GBOA 5CXAA 1ZP5A 4PKQA 1A86A 3LIRA 1KAPP 1R55A 1OO9A 1O0TA 1G9KA 3F15A 1C3IA 1UTZA 3LE9A 1ZTQA 1JANA 2ERPA 1XUDA 1SRPA 4GR8A 2J0TA 1BKCE 2WOAA 4ON1A 3L0VA 1KUKA 3EDHA 3F17A 3DPEA 1IACA 3HDBA 1JK3A 2DW0A 1EAKA 3F18A 4H84A 1D7XA 4WF6A 4I35A 1UMTA 1MMRA 1OS9A 5B5PA 2JT5A 1HV5A 4EFSA 4R3VA 5BOTA 1QJJA 2OY4A 4JP4A 4PKSA 1QIBA 1GKCA 2A8HA 3B92A 1FM1A 1MMQA 3RTTA 2OXZA 1XFVA 5D3CA 1JH1A 3E8RA 3LQBA 3LMCA 1G4KA 2W12A 1MMPA 5D2BA 1D8FA 3AIGA 2L0RA 1GXDA 1USNA 3KEKA 2KRJA 3DPFA 5B5OA 1HFSA 2JSDA 4GR0A 3I7IA 4FVLA 1XFZA 4FXQA 1XFWA 2Z2DA 3TT4A 4H49A 1Y8JA 4PKTA 1ZXVA 5BPAA 3NX7A 1PWUA 4DD8A 3AYKA 2X3CA 2USNA 4H30A 1D8MA 4ILWD 3BA0A 3HB2P 3U1RA 1CGEA 4DV8A 1KUFA 2DDYA 2MZIA 3EWJA 1BUVM 1HOVA 1K7IA 1PWVA 3N2VA 5I2ZA 1ZS0A 1GO8P 2OXUA 1UEAA 2OXWA 3TSKA 2FV5A 4AUOA 1UMSA 4XM6A 1K7GA 3Q2GA 1KBCA 4XM7A 1IADA 4L63A
chains in the Genus database with same CATH superfamily
1ZVXA 1L6JA 456CA 1CAQA 3O2XA 1XM5A 4FXYP 4DPEA 3HBUP 2W14A 4WZVA 1KUHA 1JKYA 3DTEA 3F16A 1Y93A 3ZVSA 4HMAA 4GR3A 2OZRA 1GKDA 3KMCA 3LGPA 3O64A 4GUYA 4GWNA 3ELMA 1JAOA 2CLTA 4J4MA 3ZXHA 1PWWA 1OS2A 1A85A 5CUHA 3G5CA 3K7NA 3AYUA 4AYKA 1C8TA 1SATA 1FLSA 3LIKA 1MNCA 1JIWP 1YQYA 2AYKA 1BUDA 5D7WA 2TCLA 1BKCA 2WO9A 4HX3A 1ZXCA 3P24A 1AKLA 3EHXA 1B3DA 2MZEA 3B2ZA 1QUAA 4WK7A 3KHIA 3KMEA 5I43A 1HFCA 2SRTA 3MA2A 4G9LA 2Y6CA 2YUFA 4JQGA 1XFXA 1G49A 5D1SA 4JPAA 3LQ0A 3K7LA 3Q2HA 2J83A 3G42A 2OVZA 3EDIA 2OI0A 1DTHA 3HDAP 966CA 2K9CA 4WKIA 2X3AA 1S4BP 2W15A 4H2EA 2DW1A 3KWVC 3L0TA 4IUWA 3VI1A 1JIZA 2OVXA 3DTIA 1J7NA 3F19A 2X7MA 3WV2A 1IAAA 2XS4A 2OW1A 1D5JA 1ROSA 1BKCI 1GE7A 2HU6A 3TS4A 1IAGA 3DL1A 4DF9A 3EDGA 1UTTA 1I76A 2Y6DA 1BM6A 1IAEA 3HY9A 4H82A 3USNA 3RTSA 4Q1LA 1AF0A 3EHYA 1PWQA 1SMPA 1BIWA 4JA1A 3LEAA 2MZHA 3I7GA 3VTGA 1R1JA 2MLRA 1XURA 2O3EA 5H8XA 3CKIA 1BQOA 1GO7P 3HBVP 1ASTA 2POJA 3LJTA 2WO8A 1SLMA 3P1VA 3UVCA 2E3XA 4GQLA 1JAPA 1JJ9A 2EROA 3SHIA 1WNIA 4QKZA 1YCMA 3LUNA 1OM8A 1OMJA 4GWMA 4XCTA 1BZSA 1C7KA 1QICA 2W0DA 1JAQA 5D1UA 5L7FA 1I1IP 3HY7A 5I0LA 2DW2A 3N2UA 1R54A 4G0DA 3HYGA 4H3XA 4WKEA 1RM8A 2FV9A 2OW2A 1Y0VA 3LK8A 4PKVA 5I4OA 3B8ZA 4AXQA 5JMYA 4IJOA 1G05A 3DWBA 1GE6A 2JT6A 4PKUA 3WV1A 1I73A 3DSLA 3KRYA 4ZR5A 1KUGA 1YP1A 5L79A 1O0QA 3F1AA 4A7BA 5LABA 4IN9A 1Q3AA 2JIHA 1XFYA 2JNPA 1XAXA 2E2DA 4I03A 4L6TA 5CZMA 1CGFA 1EUBA 2OW9A 3V96B 1OM6A 2XS3A 1BQQM 4FU4A 1SU3A 4PKWA 1GE5A 5I12A 1SLNA 3TVCA 1MMBA 1EB6A 1KUIA 4PKRA 1AYKA 2MLSA 2YIGA 830CA 3ZUKA 2ERQA 2N8RA 2D1NA 3EDZA 1IABA 1DMTA 2I47A 1CK7A 3OHLA 3KEJA 1HY7A 1PWPA 2OW0A 1YOUA 1RMZA 4GF1A 1TVIA 1R1HA 3LUMA 3LJZA 3DTKA 1XFUA 2RJQA 2D1OA 1BSWA 4CTHA 5BOYA 3DNGA 4AIGA 2AIGP 2CKIA 1HTDA 1OM7A 1G12A 1H71P 2O36A 1CGLA 2RJPA 2OY2A 1CQRA 1B8YA 2V4BA 2K2GA 2QPJA 2X3BA 3LJGA 3OHOA 2W13A 4XBHA 1ND1A 5I3MA 3LILA 4XM8A 3LKAA 1R1IA 2DDFA 4H76A 1K7QA 4JIJA 3WV3A 5D1TA 2YB9A 1CXVA 1XUCA 1ATLA 1FBLA 3KECA 1Z3JA 4A3WA 4L19A 2PJTA 4H1QA 1QIAA 1CIZA 1QJIA 3GBOA 5CXAA 1ZP5A 4PKQA 1A86A 3LIRA 1KAPP 1R55A 1OO9A 1O0TA 1G9KA 3F15A 1C3IA 1UTZA 3LE9A 1ZTQA 1JANA 2ERPA 1XUDA 1SRPA 4GR8A 2J0TA 1BKCE 2WOAA 4ON1A 3L0VA 1KUKA 3EDHA 3F17A 3DPEA 1IACA 3HDBA 1JK3A 2DW0A 1EAKA 3F18A 4H84A 1D7XA 4WF6A 4I35A 1UMTA 1MMRA 1OS9A 5B5PA 2JT5A 1HV5A 4EFSA 4R3VA 5BOTA 1QJJA 2OY4A 4JP4A 4PKSA 1QIBA 4L7AA 1GKCA 2A8HA 3B92A 1FM1A 1MMQA 3RTTA 2OXZA 1XFVA 5D3CA 1JH1A 3E8RA 3LQBA 3LMCA 1G4KA 2W12A 1MMPA 5D2BA 1D8FA 3AIGA 2L0RA 1GXDA 1USNA 3KEKA 1OZ9A 2KRJA 3DPFA 5B5OA 1HFSA 2JSDA 4GR0A 3I7IA 4FVLA 1XFZA 4FXQA 1XFWA 2Z2DA 3TT4A 4H49A 1Y8JA 4PKTA 1ZXVA 5BPAA 3NX7A 1PWUA 4DD8A 3AYKA 2X3CA 2USNA 4H30A 1D8MA 4ILWD 3BA0A 3HB2P 3U1RA 1CGEA 4DV8A 1KUFA 2DDYA 2MZIA 3EWJA 1BUVM 1HOVA 1K7IA 1PWVA 3N2VA 5I2ZA 1ZS0A 1GO8P 2OXUA 1UEAA 2OXWA 3TSKA 2FV5A 4AUOA 1UMSA 4XM6A 1K7GA 3Q2GA 1KBCA 4XM7A 1IADA 4L63A
chains in the Genus database with same CATH topology
1ZVXA 1L6JA 456CA 1CAQA 3O2XA 4FXYP 4DPEA 3HBUP 2W14A 4WZVA 1KUHA 1JKYA 3DTEA 3F16A 1Y93A 3ZVSA 4HMAA 4GR3A 2OZRA 1GKDA 3KMCA 3LGPA 3O64A 4GUYA 4GWNA 3ELMA 1JAOA 2CLTA 4J4MA 3ZXHA 1PWWA 1OS2A 1A85A 5CUHA 3G5CA 3K7NA 3AYUA 4AYKA 1C8TA 1SATA 1FLSA 3LIKA 1MNCA 1JIWP 1YQYA 2AYKA 1BUDA 5D7WA 2TCLA 1BKCA 2WO9A 4HX3A 1ZXCA 3P24A 1AKLA 3EHXA 1B3DA 2MZEA 3B2ZA 1QUAA 4WK7A 3KHIA 3KMEA 5I43A 1HFCA 2SRTA 3MA2A 4G9LA 2Y6CA 2YUFA 4JQGA 1XFXA 1G49A 5D1SA 4JPAA 3LQ0A 3K7LA 3Q2HA 2J83A 3G42A 2OVZA 3EDIA 2OI0A 1DTHA 3HDAP 966CA 2K9CA 4WKIA 2X3AA 1S4BP 2W15A 4H2EA 2DW1A 3KWVC 3L0TA 4IUWA 3VI1A 1JIZA 2OVXA 3DTIA 1J7NA 3F19A 2X7MA 3WV2A 1IAAA 2XS4A 2OW1A 1D5JA 1ROSA 1BKCI 1GE7A 2HU6A 3TS4A 1IAGA 3DL1A 4DF9A 3EDGA 1UTTA 1I76A 2Y6DA 1BM6A 1IAEA 3HY9A 4H82A 3USNA 3RTSA 4Q1LA 1AF0A 3EHYA 1PWQA 1SMPA 1BIWA 4JA1A 3LEAA 2MZHA 3I7GA 3VTGA 1R1JA 2MLRA 1XURA 2O3EA 5H8XA 3CKIA 1BQOA 1GO7P 3HBVP 1ASTA 2POJA 3LJTA 2WO8A 1SLMA 3P1VA 3UVCA 2E3XA 4GQLA 1JAPA 1JJ9A 2EROA 3SHIA 1WNIA 4QKZA 1YCMA 3LUNA 1OM8A 1OMJA 4GWMA 4XCTA 1BZSA 1C7KA 1QICA 2W0DA 1JAQA 5D1UA 5L7FA 1I1IP 3HY7A 5I0LA 2DW2A 3N2UA 1R54A 4G0DA 3HYGA 4H3XA 4WKEA 1RM8A 2FV9A 2OW2A 1Y0VA 3LK8A 4PKVA 5I4OA 3B8ZA 4AXQA 5JMYA 4IJOA 1G05A 3DWBA 1GE6A 2JT6A 4PKUA 3WV1A 1I73A 3DSLA 3KRYA 4ZR5A 1KUGA 1YP1A 5L79A 1O0QA 3F1AA 4A7BA 5LABA 4IN9A 1Q3AA 2JIHA 1XFYA 2JNPA 2E2DA 4I03A 4L6TA 5CZMA 1CGFA 1EUBA 2OW9A 3V96B 1OM6A 2XS3A 1BQQM 4FU4A 1SU3A 4PKWA 1GE5A 5I12A 1SLNA 3TVCA 1MMBA 1EB6A 1KUIA 4PKRA 1AYKA 2MLSA 2YIGA 830CA 3ZUKA 2ERQA 2N8RA 2D1NA 3EDZA 1IABA 1DMTA 2I47A 1CK7A 3OHLA 3KEJA 1HY7A 1PWPA 2OW0A 1YOUA 1RMZA 4GF1A 3LUMA 1R1HA 3LJZA 3DTKA 1XFUA 2RJQA 2D1OA 1BSWA 4CTHA 5BOYA 3DNGA 4AIGA 2AIGP 2CKIA 1HTDA 1OM7A 1G12A 1H71P 2O36A 1CGLA 2RJPA 2OY2A 1CQRA 1B8YA 2V4BA 2K2GA 2QPJA 2X3BA 3LJGA 3OHOA 2W13A 4XBHA 1ND1A 5I3MA 3LILA 4XM8A 3LKAA 1R1IA 2DDFA 4H76A 1K7QA 4JIJA 3WV3A 5D1TA 2YB9A 1CXVA 1XUCA 1ATLA 1FBLA 3KECA 1Z3JA 4A3WA 4L19A 2PJTA 4H1QA 1QIAA 1CIZA 1QJIA 3GBOA 5CXAA 1ZP5A 4PKQA 1A86A 3LIRA 1KAPP 1R55A 1OO9A 1O0TA 1G9KA 3F15A 1C3IA 1UTZA 3LE9A 1ZTQA 1JANA 2ERPA 1XUDA 1SRPA 4GR8A 2J0TA 1BKCE 2WOAA 4ON1A 3L0VA 1KUKA 3EDHA 3F17A 3DPEA 1IACA 3HDBA 1JK3A 2DW0A 1EAKA 3F18A 4H84A 1D7XA 4WF6A 4I35A 1UMTA 1MMRA 1OS9A 5B5PA 2JT5A 1HV5A 4EFSA 4R3VA 5BOTA 1QJJA 2OY4A 4JP4A 4PKSA 1QIBA 4L7AA 1GKCA 2A8HA 3B92A 1FM1A 1MMQA 3RTTA 2OXZA 1XFVA 5D3CA 1JH1A 3E8RA 3LQBA 3LMCA 1G4KA 2W12A 1MMPA 5D2BA 1D8FA 3AIGA 2L0RA 1GXDA 1USNA 3KEKA 2KRJA 3DPFA 5B5OA 1HFSA 2JSDA 4GR0A 3I7IA 4FVLA 1XFZA 4FXQA 1XFWA 2Z2DA 3TT4A 4H49A 1Y8JA 4PKTA 1ZXVA 5BPAA 3NX7A 1PWUA 4DD8A 3AYKA 2X3CA 2USNA 4H30A 1D8MA 4ILWD 3BA0A 3HB2P 3U1RA 1CGEA 4DV8A 1KUFA 2DDYA 2MZIA 3EWJA 1BUVM 1HOVA 1K7IA 1PWVA 3N2VA 5I2ZA 1ZS0A 1GO8P 2OXUA 1UEAA 2OXWA 3TSKA 2FV5A 4AUOA 1UMSA 4XM6A 1K7GA 3Q2GA 1KBCA 4XM7A 1IADA 4L63A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZVX A;  1L6J A;  456C A;  1CAQ A;  3O2X A;  4FXY P;  4DPE A;  3HBU P;  2W14 A;  4WZV A;  1KUH A;  1JKY A;  3F16 A;  1Y93 A;  3ZVS A;  4HMA A;  4GR3 A;  2OZR A;  1GKD A;  3KMC A;  3LGP A;  3O64 A;  4GUY A;  4GWN A;  3ELM A;  1JAO A;  2CLT A;  4J4M A;  3ZXH A;  1PWW A;  1OS2 A;  1A85 A;  5CUH A;  3G5C A;  3K7N A;  3AYU A;  4AYK A;  1C8T A;  1SAT A;  1FLS A;  3LIK A;  1MNC A;  1JIW P;  1YQY A;  2AYK A;  1BUD A;  5D7W A;  2TCL A;  1BKC A;  2WO9 A;  4HX3 A;  1ZXC A;  3P24 A;  1AKL A;  3EHX A;  1B3D A;  2MZE A;  3B2Z A;  1QUA A;  4WK7 A;  3KHI A;  3KME A;  5I43 A;  1HFC A;  2SRT A;  3MA2 A;  4G9L A;  2Y6C A;  4JQG A;  1XFX A;  1G49 A;  5D1S A;  4JPA A;  3LQ0 A;  3K7L A;  3Q2H A;  2J83 A;  3G42 A;  2OVZ A;  3EDI A;  2OI0 A;  1DTH A;  3HDA P;  966C A;  2K9C A;  4WKI A;  2X3A A;  1S4B P;  2W15 A;  4H2E A;  2DW1 A;  3KWV C;  3L0T A;  4IUW A;  3VI1 A;  1JIZ A;  2OVX A;  1J7N A;  3F19 A;  2X7M A;  3WV2 A;  1IAA A;  2XS4 A;  2OW1 A;  1D5J A;  1ROS A;  1BKC I;  1GE7 A;  2HU6 A;  3TS4 A;  1IAG A;  3DL1 A;  4DF9 A;  3EDG A;  1UTT A;  1I76 A;  2Y6D A;  1BM6 A;  1IAE A;  3HY9 A;  4H82 A;  3USN A;  3RTS A;  4Q1L A;  1AF0 A;  3EHY A;  1PWQ A;  1SMP A;  1BIW A;  4JA1 A;  3LEA A;  2MZH A;  3I7G A;  3VTG A;  1R1J A;  2MLR A;  1XUR A;  2O3E A;  5H8X A;  3CKI A;  1BQO A;  1GO7 P;  3HBV P;  1AST A;  2POJ A;  3LJT A;  2WO8 A;  1SLM A;  3P1V A;  3UVC A;  2E3X A;  4GQL A;  1JAP A;  1JJ9 A;  2ERO A;  3SHI A;  1WNI A;  4QKZ A;  1YCM A;  3LUN A;  1OM8 A;  1OMJ A;  4GWM A;  4XCT A;  1BZS A;  1C7K A;  1QIC A;  2W0D A;  1JAQ A;  5D1U A;  5L7F A;  1I1I P;  3HY7 A;  5I0L A;  2DW2 A;  3N2U A;  1R54 A;  4G0D A;  3HYG A;  4H3X A;  4WKE A;  1RM8 A;  2FV9 A;  2OW2 A;  1Y0V A;  3LK8 A;  4PKV A;  5I4O A;  3B8Z A;  4AXQ A;  5JMY A;  4IJO A;  1G05 A;  3DWB A;  1GE6 A;  2JT6 A;  4PKU A;  3WV1 A;  1I73 A;  3DSL A;  3KRY A;  4ZR5 A;  1KUG A;  1YP1 A;  5L79 A;  1O0Q A;  3F1A A;  4A7B A;  5LAB A;  4IN9 A;  1Q3A A;  2JIH A;  1XFY A;  2JNP A;  2E2D A;  4I03 A;  4L6T A;  5CZM A;  1CGF A;  1EUB A;  2OW9 A;  3V96 B;  1OM6 A;  2XS3 A;  1BQQ M;  4FU4 A;  1SU3 A;  4PKW A;  1GE5 A;  5I12 A;  1SLN A;  3TVC A;  1MMB A;  1EB6 A;  1KUI A;  4PKR A;  1AYK A;  2MLS A;  2YIG A;  830C A;  3ZUK A;  2ERQ A;  2N8R A;  2D1N A;  3EDZ A;  1IAB A;  1DMT A;  2I47 A;  1CK7 A;  3OHL A;  3KEJ A;  1HY7 A;  1PWP A;  2OW0 A;  1YOU A;  1RMZ A;  4GF1 A;  3LUM A;  1R1H A;  3LJZ A;  1XFU A;  2RJQ A;  2D1O A;  1BSW A;  4CTH A;  5BOY A;  3DNG A;  4AIG A;  2AIG P;  2CKI A;  1HTD A;  1OM7 A;  1G12 A;  1H71 P;  2O36 A;  1CGL A;  2RJP A;  2OY2 A;  1CQR A;  1B8Y A;  2V4B A;  2K2G A;  2QPJ A;  2X3B A;  3LJG A;  3OHO A;  2W13 A;  4XBH A;  1ND1 A;  5I3M A;  3LIL A;  4XM8 A;  3LKA A;  1R1I A;  2DDF A;  4H76 A;  1K7Q A;  4JIJ A;  3WV3 A;  5D1T A;  2YB9 A;  1CXV A;  1XUC A;  1ATL A;  1FBL A;  3KEC A;  1Z3J A;  4A3W A;  4L19 A;  2PJT A;  4H1Q A;  1QIA A;  1CIZ A;  1QJI A;  3GBO A;  5CXA A;  1ZP5 A;  4PKQ A;  1A86 A;  3LIR A;  1KAP P;  1R55 A;  1OO9 A;  1O0T A;  1G9K A;  3F15 A;  1C3I A;  1UTZ A;  3LE9 A;  1ZTQ A;  1JAN A;  2ERP A;  1XUD A;  1SRP A;  4GR8 A;  2J0T A;  1BKC E;  2WOA A;  4ON1 A;  3L0V A;  1KUK A;  3EDH A;  3F17 A;  3DPE A;  1IAC A;  3HDB A;  1JK3 A;  2DW0 A;  1EAK A;  3F18 A;  4H84 A;  1D7X A;  4WF6 A;  4I35 A;  1UMT A;  1MMR A;  1OS9 A;  5B5P A;  2JT5 A;  1HV5 A;  4EFS A;  4R3V A;  5BOT A;  1QJJ A;  2OY4 A;  4JP4 A;  4PKS A;  1QIB A;  1GKC A;  2A8H A;  3B92 A;  1FM1 A;  1MMQ A;  3RTT A;  2OXZ A;  1XFV A;  5D3C A;  1JH1 A;  3E8R A;  3LQB A;  3LMC A;  1G4K A;  2W12 A;  1MMP A;  5D2B A;  1D8F A;  3AIG A;  2L0R A;  1GXD A;  1USN A;  3KEK A;  2KRJ A;  3DPF A;  5B5O A;  1HFS A;  2JSD A;  4GR0 A;  3I7I A;  4FVL A;  1XFZ A;  4FXQ A;  1XFW A;  2Z2D A;  3TT4 A;  4H49 A;  1Y8J A;  4PKT A;  1ZXV A;  5BPA A;  3NX7 A;  1PWU A;  4DD8 A;  3AYK A;  2X3C A;  2USN A;  4H30 A;  1D8M A;  4ILW D;  3BA0 A;  3HB2 P;  3U1R A;  1CGE A;  4DV8 A;  1KUF A;  2DDY A;  2MZI A;  3EWJ A;  1BUV M;  1HOV A;  1K7I A;  1PWV A;  3N2V A;  5I2Z A;  1ZS0 A;  1GO8 P;  2OXU A;  1UEA A;  2OXW A;  3TSK A;  2FV5 A;  4AUO A;  1UMS A;  4XM6 A;  1K7G A;  3Q2G A;  1KBC A;  4XM7 A;  1IAD A;  4L63 A; 
#chains in the Genus database with same CATH topology
 1ZVX A;  1L6J A;  456C A;  1CAQ A;  3O2X A;  1XM5 A;  4FXY P;  4DPE A;  3HBU P;  2W14 A;  4WZV A;  1KUH A;  1JKY A;  3DTE A;  3F16 A;  1Y93 A;  3ZVS A;  4HMA A;  4GR3 A;  2OZR A;  1GKD A;  3KMC A;  3LGP A;  3O64 A;  4GUY A;  4GWN A;  3ELM A;  1JAO A;  2CLT A;  4J4M A;  3ZXH A;  1PWW A;  1OS2 A;  1A85 A;  5CUH A;  3G5C A;  3K7N A;  3AYU A;  4AYK A;  1C8T A;  1SAT A;  1FLS A;  3LIK A;  1MNC A;  1JIW P;  1YQY A;  2AYK A;  1BUD A;  5D7W A;  2TCL A;  1BKC A;  2WO9 A;  4HX3 A;  1ZXC A;  3P24 A;  1AKL A;  3EHX A;  1B3D A;  2MZE A;  3B2Z A;  1QUA A;  4WK7 A;  3KHI A;  3KME A;  5I43 A;  1HFC A;  2SRT A;  3MA2 A;  4G9L A;  2Y6C A;  2YUF A;  4JQG A;  1XFX A;  1G49 A;  5D1S A;  4JPA A;  3LQ0 A;  3K7L A;  3Q2H A;  2J83 A;  3G42 A;  2OVZ A;  3EDI A;  2OI0 A;  1DTH A;  3HDA P;  966C A;  2K9C A;  4WKI A;  2X3A A;  1S4B P;  2W15 A;  4H2E A;  2DW1 A;  3KWV C;  3L0T A;  4IUW A;  3VI1 A;  1JIZ A;  2OVX A;  3DTI A;  1J7N A;  3F19 A;  2X7M A;  3WV2 A;  1IAA A;  2XS4 A;  2OW1 A;  1D5J A;  1ROS A;  1BKC I;  1GE7 A;  2HU6 A;  3TS4 A;  1IAG A;  3DL1 A;  4DF9 A;  3EDG A;  1UTT A;  1I76 A;  2Y6D A;  1BM6 A;  1IAE A;  3HY9 A;  4H82 A;  3USN A;  3RTS A;  4Q1L A;  1AF0 A;  3EHY A;  1PWQ A;  1SMP A;  1BIW A;  4JA1 A;  3LEA A;  2MZH A;  3I7G A;  3VTG A;  1R1J A;  2MLR A;  1XUR A;  2O3E A;  5H8X A;  3CKI A;  1BQO A;  1GO7 P;  3HBV P;  1AST A;  2POJ A;  3LJT A;  2WO8 A;  1SLM A;  3P1V A;  3UVC A;  2E3X A;  4GQL A;  1JAP A;  1JJ9 A;  2ERO A;  3SHI A;  1WNI A;  4QKZ A;  1YCM A;  3LUN A;  1OM8 A;  1OMJ A;  4GWM A;  4XCT A;  1BZS A;  1C7K A;  1QIC A;  2W0D A;  1JAQ A;  5D1U A;  5L7F A;  1I1I P;  3HY7 A;  5I0L A;  2DW2 A;  3N2U A;  1R54 A;  4G0D A;  3HYG A;  4H3X A;  4WKE A;  1RM8 A;  2FV9 A;  2OW2 A;  1Y0V A;  3LK8 A;  4PKV A;  5I4O A;  3B8Z A;  4AXQ A;  5JMY A;  4IJO A;  1G05 A;  3DWB A;  1GE6 A;  2JT6 A;  4PKU A;  3WV1 A;  1I73 A;  3DSL A;  3KRY A;  4ZR5 A;  1KUG A;  1YP1 A;  5L79 A;  1O0Q A;  3F1A A;  4A7B A;  5LAB A;  4IN9 A;  1Q3A A;  2JIH A;  1XFY A;  2JNP A;  1XAX A;  2E2D A;  4I03 A;  4L6T A;  5CZM A;  1CGF A;  1EUB A;  2OW9 A;  3V96 B;  1OM6 A;  2XS3 A;  1BQQ M;  4FU4 A;  1SU3 A;  4PKW A;  1GE5 A;  5I12 A;  1SLN A;  3TVC A;  1MMB A;  1EB6 A;  1KUI A;  4PKR A;  1AYK A;  2MLS A;  2YIG A;  830C A;  3ZUK A;  2ERQ A;  2N8R A;  2D1N A;  3EDZ A;  1IAB A;  1DMT A;  2I47 A;  1CK7 A;  3OHL A;  3KEJ A;  1HY7 A;  1PWP A;  2OW0 A;  1YOU A;  1RMZ A;  4GF1 A;  1TVI A;  1R1H A;  3LUM A;  3LJZ A;  3DTK A;  1XFU A;  2RJQ A;  2D1O A;  1BSW A;  4CTH A;  5BOY A;  3DNG A;  4AIG A;  2AIG P;  2CKI A;  1HTD A;  1OM7 A;  1G12 A;  1H71 P;  2O36 A;  1CGL A;  2RJP A;  2OY2 A;  1CQR A;  1B8Y A;  2V4B A;  2K2G A;  2QPJ A;  2X3B A;  3LJG A;  3OHO A;  2W13 A;  4XBH A;  1ND1 A;  5I3M A;  3LIL A;  4XM8 A;  3LKA A;  1R1I A;  2DDF A;  4H76 A;  1K7Q A;  4JIJ A;  3WV3 A;  5D1T A;  2YB9 A;  1CXV A;  1XUC A;  1ATL A;  1FBL A;  3KEC A;  1Z3J A;  4A3W A;  4L19 A;  2PJT A;  4H1Q A;  1QIA A;  1CIZ A;  1QJI A;  3GBO A;  5CXA A;  1ZP5 A;  4PKQ A;  1A86 A;  3LIR A;  1KAP P;  1R55 A;  1OO9 A;  1O0T A;  1G9K A;  3F15 A;  1C3I A;  1UTZ A;  3LE9 A;  1ZTQ A;  1JAN A;  2ERP A;  1XUD A;  1SRP A;  4GR8 A;  2J0T A;  1BKC E;  2WOA A;  4ON1 A;  3L0V A;  1KUK A;  3EDH A;  3F17 A;  3DPE A;  1IAC A;  3HDB A;  1JK3 A;  2DW0 A;  1EAK A;  3F18 A;  4H84 A;  1D7X A;  4WF6 A;  4I35 A;  1UMT A;  1MMR A;  1OS9 A;  5B5P A;  2JT5 A;  1HV5 A;  4EFS A;  4R3V A;  5BOT A;  1QJJ A;  2OY4 A;  4JP4 A;  4PKS A;  1QIB A;  4L7A A;  1GKC A;  2A8H A;  3B92 A;  1FM1 A;  1MMQ A;  3RTT A;  2OXZ A;  1XFV A;  5D3C A;  1JH1 A;  3E8R A;  3LQB A;  3LMC A;  1G4K A;  2W12 A;  1MMP A;  5D2B A;  1D8F A;  3AIG A;  2L0R A;  1GXD A;  1USN A;  3KEK A;  1OZ9 A;  2KRJ A;  3DPF A;  5B5O A;  1HFS A;  2JSD A;  4GR0 A;  3I7I A;  4FVL A;  1XFZ A;  4FXQ A;  1XFW A;  2Z2D A;  3TT4 A;  4H49 A;  1Y8J A;  4PKT A;  1ZXV A;  5BPA A;  3NX7 A;  1PWU A;  4DD8 A;  3AYK A;  2X3C A;  2USN A;  4H30 A;  1D8M A;  4ILW D;  3BA0 A;  3HB2 P;  3U1R A;  1CGE A;  4DV8 A;  1KUF A;  2DDY A;  2MZI A;  3EWJ A;  1BUV M;  1HOV A;  1K7I A;  1PWV A;  3N2V A;  5I2Z A;  1ZS0 A;  1GO8 P;  2OXU A;  1UEA A;  2OXW A;  3TSK A;  2FV5 A;  4AUO A;  1UMS A;  4XM6 A;  1K7G A;  3Q2G A;  1KBC A;  4XM7 A;  1IAD A;  4L63 A; 
#chains in the Genus database with same CATH homology
 1ZVX A;  1L6J A;  456C A;  1CAQ A;  3O2X A;  4FXY P;  4DPE A;  3HBU P;  2W14 A;  4WZV A;  1KUH A;  1JKY A;  3DTE A;  3F16 A;  1Y93 A;  3ZVS A;  4HMA A;  4GR3 A;  2OZR A;  1GKD A;  3KMC A;  3LGP A;  3O64 A;  4GUY A;  4GWN A;  3ELM A;  1JAO A;  2CLT A;  4J4M A;  3ZXH A;  1PWW A;  1OS2 A;  1A85 A;  5CUH A;  3G5C A;  3K7N A;  3AYU A;  4AYK A;  1C8T A;  1SAT A;  1FLS A;  3LIK A;  1MNC A;  1JIW P;  1YQY A;  2AYK A;  1BUD A;  5D7W A;  2TCL A;  1BKC A;  2WO9 A;  4HX3 A;  1ZXC A;  3P24 A;  1AKL A;  3EHX A;  1B3D A;  2MZE A;  3B2Z A;  1QUA A;  4WK7 A;  3KHI A;  3KME A;  5I43 A;  1HFC A;  2SRT A;  3MA2 A;  4G9L A;  2Y6C A;  2YUF A;  4JQG A;  1XFX A;  1G49 A;  5D1S A;  4JPA A;  3LQ0 A;  3K7L A;  3Q2H A;  2J83 A;  3G42 A;  2OVZ A;  3EDI A;  2OI0 A;  1DTH A;  3HDA P;  966C A;  2K9C A;  4WKI A;  2X3A A;  1S4B P;  2W15 A;  4H2E A;  2DW1 A;  3KWV C;  3L0T A;  4IUW A;  3VI1 A;  1JIZ A;  2OVX A;  3DTI A;  1J7N A;  3F19 A;  2X7M A;  3WV2 A;  1IAA A;  2XS4 A;  2OW1 A;  1D5J A;  1ROS A;  1BKC I;  1GE7 A;  2HU6 A;  3TS4 A;  1IAG A;  3DL1 A;  4DF9 A;  3EDG A;  1UTT A;  1I76 A;  2Y6D A;  1BM6 A;  1IAE A;  3HY9 A;  4H82 A;  3USN A;  3RTS A;  4Q1L A;  1AF0 A;  3EHY A;  1PWQ A;  1SMP A;  1BIW A;  4JA1 A;  3LEA A;  2MZH A;  3I7G A;  3VTG A;  1R1J A;  2MLR A;  1XUR A;  2O3E A;  5H8X A;  3CKI A;  1BQO A;  1GO7 P;  3HBV P;  1AST A;  2POJ A;  3LJT A;  2WO8 A;  1SLM A;  3P1V A;  3UVC A;  2E3X A;  4GQL A;  1JAP A;  1JJ9 A;  2ERO A;  3SHI A;  1WNI A;  4QKZ A;  1YCM A;  3LUN A;  1OM8 A;  1OMJ A;  4GWM A;  4XCT A;  1BZS A;  1C7K A;  1QIC A;  2W0D A;  1JAQ A;  5D1U A;  5L7F A;  1I1I P;  3HY7 A;  5I0L A;  2DW2 A;  3N2U A;  1R54 A;  4G0D A;  3HYG A;  4H3X A;  4WKE A;  1RM8 A;  2FV9 A;  2OW2 A;  1Y0V A;  3LK8 A;  4PKV A;  5I4O A;  3B8Z A;  4AXQ A;  5JMY A;  4IJO A;  1G05 A;  3DWB A;  1GE6 A;  2JT6 A;  4PKU A;  3WV1 A;  1I73 A;  3DSL A;  3KRY A;  4ZR5 A;  1KUG A;  1YP1 A;  5L79 A;  1O0Q A;  3F1A A;  4A7B A;  5LAB A;  4IN9 A;  1Q3A A;  2JIH A;  1XFY A;  2JNP A;  2E2D A;  4I03 A;  4L6T A;  5CZM A;  1CGF A;  1EUB A;  2OW9 A;  3V96 B;  1OM6 A;  2XS3 A;  1BQQ M;  4FU4 A;  1SU3 A;  4PKW A;  1GE5 A;  5I12 A;  1SLN A;  3TVC A;  1MMB A;  1EB6 A;  1KUI A;  4PKR A;  1AYK A;  2MLS A;  2YIG A;  830C A;  3ZUK A;  2ERQ A;  2N8R A;  2D1N A;  3EDZ A;  1IAB A;  1DMT A;  2I47 A;  1CK7 A;  3OHL A;  3KEJ A;  1HY7 A;  1PWP A;  2OW0 A;  1YOU A;  1RMZ A;  4GF1 A;  3LUM A;  1R1H A;  3LJZ A;  3DTK A;  1XFU A;  2RJQ A;  2D1O A;  1BSW A;  4CTH A;  5BOY A;  3DNG A;  4AIG A;  2AIG P;  2CKI A;  1HTD A;  1OM7 A;  1G12 A;  1H71 P;  2O36 A;  1CGL A;  2RJP A;  2OY2 A;  1CQR A;  1B8Y A;  2V4B A;  2K2G A;  2QPJ A;  2X3B A;  3LJG A;  3OHO A;  2W13 A;  4XBH A;  1ND1 A;  5I3M A;  3LIL A;  4XM8 A;  3LKA A;  1R1I A;  2DDF A;  4H76 A;  1K7Q A;  4JIJ A;  3WV3 A;  5D1T A;  2YB9 A;  1CXV A;  1XUC A;  1ATL A;  1FBL A;  3KEC A;  1Z3J A;  4A3W A;  4L19 A;  2PJT A;  4H1Q A;  1QIA A;  1CIZ A;  1QJI A;  3GBO A;  5CXA A;  1ZP5 A;  4PKQ A;  1A86 A;  3LIR A;  1KAP P;  1R55 A;  1OO9 A;  1O0T A;  1G9K A;  3F15 A;  1C3I A;  1UTZ A;  3LE9 A;  1ZTQ A;  1JAN A;  2ERP A;  1XUD A;  1SRP A;  4GR8 A;  2J0T A;  1BKC E;  2WOA A;  4ON1 A;  3L0V A;  1KUK A;  3EDH A;  3F17 A;  3DPE A;  1IAC A;  3HDB A;  1JK3 A;  2DW0 A;  1EAK A;  3F18 A;  4H84 A;  1D7X A;  4WF6 A;  4I35 A;  1UMT A;  1MMR A;  1OS9 A;  5B5P A;  2JT5 A;  1HV5 A;  4EFS A;  4R3V A;  5BOT A;  1QJJ A;  2OY4 A;  4JP4 A;  4PKS A;  1QIB A;  4L7A A;  1GKC A;  2A8H A;  3B92 A;  1FM1 A;  1MMQ A;  3RTT A;  2OXZ A;  1XFV A;  5D3C A;  1JH1 A;  3E8R A;  3LQB A;  3LMC A;  1G4K A;  2W12 A;  1MMP A;  5D2B A;  1D8F A;  3AIG A;  2L0R A;  1GXD A;  1USN A;  3KEK A;  2KRJ A;  3DPF A;  5B5O A;  1HFS A;  2JSD A;  4GR0 A;  3I7I A;  4FVL A;  1XFZ A;  4FXQ A;  1XFW A;  2Z2D A;  3TT4 A;  4H49 A;  1Y8J A;  4PKT A;  1ZXV A;  5BPA A;  3NX7 A;  1PWU A;  4DD8 A;  3AYK A;  2X3C A;  2USN A;  4H30 A;  1D8M A;  4ILW D;  3BA0 A;  3HB2 P;  3U1R A;  1CGE A;  4DV8 A;  1KUF A;  2DDY A;  2MZI A;  3EWJ A;  1BUV M;  1HOV A;  1K7I A;  1PWV A;  3N2V A;  5I2Z A;  1ZS0 A;  1GO8 P;  2OXU A;  1UEA A;  2OXW A;  3TSK A;  2FV5 A;  4AUO A;  1UMS A;  4XM6 A;  1K7G A;  3Q2G A;  1KBC A;  4XM7 A;  1IAD A;  4L63 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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