3CKIA

Crystal structure of the tace-n-timp-3 complex
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
256
structure length
256
Chain Sequence
DPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural determinants of the ADAM inhibition by TIMP-3: crystal structure of the TACE-N-TIMP-3 complex.
pubmed doi rcsb
molecule tags Hydrolase, hydrolase inhibitor
source organism Homo sapiens
molecule keywords ADAM 17
total genus 82
structure length 256
sequence length 256
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2008-03-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3ckiA00
3AIGA 1G9KA 1D8FA 3B2ZA 2SRTA 3OHLA 1UTTA 1A86A 1CGEA 3LJGA 3LMCA 1OS2A 2K9CA 2AYKA 2W13A 3GBOA 4WKEA 2JT5A 1JAPA 1B3DA 1R1HA 4WKIA 2MZEA 2XS4A 1G05A 4GWMA 1C7KA 3L0TA 4XM6A 2O3EA 1BQQM 3F1AA 1QUAA 1GE6A 1XFVA 1XURA 3KEJA 3HDAP 3I7GA 1SU3A 3HYGA 5B5OA 1G12A 4H76A 966CA 1ND1A 1UMTA 3Q2HA 2W12A 1MMRA 1EUBA 1FM1A 3LJTA 1SMPA 2WO9A 5BOTA 3TT4A 2POJA 1C3IA 1GKDA 4DF9A 2DW0A 3LILA 3VI1A 4JA1A 2CLTA 2JNPA 4L63A 1BUVM 2J0TA 5D7WA 2I47A 1IAAA 1GKCA 3KEKA 5BOYA 1HY7A 2J83A 3LUNA 4FXYP 1QJIA 3EHXA 1BM6A 1XFXA 1CGFA 3KWVC 1HFSA 3KECA 1AYKA 4JP4A 3B92A 1UTZA 4DD8A 1HOVA 1HV5A 1CK7A 2OW1A 1D8MA 1YQYA 3MA2A 5BPAA 2PJTA 4PKTA 1PWVA 1A85A 1I76A 1KUFA 4J4MA 1Y93A 1IADA 5D2BA 2HU6A 1XFWA 1JIZA 1YCMA 1JKYA 5D1SA 2RJPA 4L19A 1BQOA 3EDHA 1QICA 3EDIA 3CKIA 4IN9A 5I3MA 1JIWP 4H1QA 1ZXCA 4AXQA 1PWQA 2D1NA 2OW0A 1D7XA 1KAPP 1R1JA 1GE5A 2Y6DA 5I2ZA 3N2UA 2D1OA 3K7NA 1S4BP 1BSWA 1MMQA 1Y0VA 4GWNA 2K2GA 1XFUA 1CXVA 2WOAA 3F16A 4ZR5A 3RTSA 4PKWA 3UVCA 1MNCA 2FV5A 4GR0A 3E8RA 4I35A 1ZTQA 4PKQA 3LIKA 1D5JA 2JIHA 4IUWA 2OXZA 1QIBA 1UMSA 3TVCA 3LEAA 2OXUA 2V4BA 1OS9A 1CIZA 1K7GA 4GQLA 4I03A 3OHOA 3LUMA 4H3XA 2USNA 2TCLA 1GO7P 2X7MA 4H30A 2DDFA 4WK7A 4GUYA 1R54A 3F19A 1WNIA 4FXQA 1ZXVA 1HFCA 1BKCA 1BUDA 2JSDA 3L0VA 1QIAA 1SLNA 4WZVA 456CA 1RM8A 3F17A 3AYKA 1OM7A 3TS4A 3DNGA 2QPJA 3WV2A 2W0DA 3LGPA 1IABA 4GF1A 1C8TA 3B8ZA 1IAGA 1J7NA 1O0QA 1Q3AA 1YP1A 1ZS0A 1I73A 5B5PA 2ERPA 2W15A 5D3CA 3WV1A 4H49A 1AF0A 3LQBA 3AYUA 3KHIA 1O0TA 5CXAA 1KBCA 2OY2A 4JIJA 2W14A 2X3CA 1YOUA 3N2VA 1JAQA 2OW2A 3G42A 2E2DA 1FBLA 1OO9A 1DTHA 1K7QA 2WO8A 5CUHA 3EWJA 830CA 1IACA 3I7IA 3LJZA 1JH1A 2MZHA 3DPEA 5D1UA 1QJJA 3LE9A 1CGLA 2MLRA 1PWWA 3F18A 1XFZA 1ZP5A 5L7FA 1JJ9A 1AKLA 3ZUKA 3TSKA 1BKCE 4XCTA 4H84A 1JK3A 1MMPA 4AUOA 5JMYA 3O64A 2OZRA 3SHIA 3F15A 1DMTA 4HMAA 2OI0A 3P1VA 1I1IP 3HBUP 4L6TA 1KUHA 3HB2P 1XUDA 2MZIA 1PWUA 1BKCI 3VTGA 1XUCA 2KRJA 5I4OA 3U1RA 4Q1LA 5H8XA 2OW9A 1RMZA 2JT6A 3G5CA 3LIRA 1MMBA 4AYKA 1B8YA 3ELMA 5D1TA 5LABA 4A7BA 1ROSA 1OM8A 3DPFA 3ZVSA 3KMEA 1R55A 4EFSA 2MLSA 2DDYA 5I43A 4H2EA 1Z3JA 1UEAA 1OMJA 2N8RA 1GXDA 3V96B 3EDZA 3DWBA 3HY7A 3KMCA 4AIGA 5I0LA 4GR3A 1KUGA 4G0DA 1G4KA 1IAEA 2A8HA 3P24A 4H82A 3LKAA 4HX3A 1PWPA 1H71P 4CTHA 4G9LA 1CAQA 3WV3A 2CKIA 3Q2GA 1CQRA 1GE7A 2X3BA 4JPAA 2RJQA 1EAKA 1SLMA 1K7IA 3LQ0A 4GR8A 4PKSA 4DV8A 2EROA 1HTDA 1XFYA 3HDBA 1FLSA 1EB6A 2YIGA 3K7LA 2AIGP 2XS3A 3BA0A 2DW1A 3ZXHA 4FVLA 3NX7A 3USNA 2OY4A 3EDGA 5CZMA 1ATLA 1JAOA 2OVXA 2L0RA 2Z2DA 4XBHA 1KUKA 3HBVP 4XM8A 2E3XA 4QKZA 2FV9A 1Y8JA 3LK8A 1SATA 4R3VA 1L6JA 1GO8P 3RTTA 1KUIA 1ZVXA 1G49A 1USNA 4DPEA 3DSLA 4PKRA 2O36A 1JANA 1ASTA 4ILWD 4PKVA 4A3WA 2DW2A 1BIWA 3KRYA 2Y6CA 5L79A 1OM6A 4XM7A 2OXWA 5I12A 3O2XA 3EHYA 2ERQA 1R1IA 1SRPA 4PKUA 2X3AA 2YB9A 2OVZA 1BZSA 4WF6A 4FU4A 4IJOA 4ON1A 4JQGA 3DL1A 3HY9A
chains in the Genus database with same CATH superfamily
3AIGA 1G9KA 1D8FA 3B2ZA 2SRTA 3OHLA 1UTTA 1A86A 1CGEA 3LJGA 3LMCA 1OS2A 2K9CA 2AYKA 2W13A 3GBOA 1OZ9A 4WKEA 2JT5A 1JAPA 1B3DA 1R1HA 4WKIA 2MZEA 2XS4A 1G05A 4GWMA 1C7KA 3L0TA 4XM6A 2O3EA 1BQQM 3F1AA 1QUAA 1GE6A 1XFVA 1XURA 3KEJA 3HDAP 1TVIA 3I7GA 1SU3A 3HYGA 5B5OA 1G12A 4H76A 966CA 1ND1A 4L7AA 1UMTA 3Q2HA 2W12A 1MMRA 1EUBA 1FM1A 3LJTA 1SMPA 2WO9A 5BOTA 3TT4A 2POJA 1C3IA 1GKDA 4DF9A 2DW0A 3LILA 3VI1A 4JA1A 2CLTA 2JNPA 4L63A 1BUVM 2J0TA 5D7WA 2I47A 1IAAA 1GKCA 3KEKA 5BOYA 1HY7A 2J83A 3LUNA 4FXYP 1QJIA 3EHXA 1BM6A 1XFXA 1CGFA 3KWVC 1HFSA 3KECA 1AYKA 4JP4A 3B92A 1UTZA 4DD8A 1HOVA 1HV5A 1CK7A 2OW1A 1D8MA 1YQYA 3MA2A 5BPAA 2PJTA 4PKTA 1PWVA 1A85A 1I76A 1KUFA 4J4MA 1Y93A 1IADA 5D2BA 2HU6A 1XFWA 1JIZA 1YCMA 1JKYA 5D1SA 2RJPA 4L19A 1BQOA 3EDHA 1QICA 3EDIA 3CKIA 4IN9A 5I3MA 1JIWP 4H1QA 1ZXCA 4AXQA 1PWQA 2D1NA 2OW0A 1D7XA 1KAPP 1R1JA 1GE5A 2Y6DA 5I2ZA 3N2UA 2D1OA 3K7NA 1S4BP 1BSWA 1MMQA 1Y0VA 4GWNA 2K2GA 1XFUA 1CXVA 2WOAA 3F16A 4ZR5A 1XM5A 3RTSA 4PKWA 3UVCA 1MNCA 2FV5A 4GR0A 3E8RA 4I35A 1ZTQA 4PKQA 3LIKA 1D5JA 2JIHA 4IUWA 2OXZA 1QIBA 1UMSA 3TVCA 3LEAA 2OXUA 2V4BA 1OS9A 1CIZA 1K7GA 4GQLA 4I03A 3OHOA 3LUMA 4H3XA 2USNA 2TCLA 1GO7P 2X7MA 4H30A 2DDFA 4WK7A 4GUYA 1R54A 3F19A 1WNIA 4FXQA 1ZXVA 1HFCA 1BKCA 1BUDA 2JSDA 3L0VA 1QIAA 1SLNA 4WZVA 456CA 1RM8A 3F17A 3AYKA 1OM7A 3TS4A 3DNGA 2QPJA 3WV2A 2W0DA 3LGPA 1IABA 4GF1A 1C8TA 3B8ZA 1IAGA 1J7NA 1O0QA 1Q3AA 1YP1A 1ZS0A 1I73A 5B5PA 2ERPA 2W15A 5D3CA 3WV1A 4H49A 1AF0A 3LQBA 3AYUA 3KHIA 1O0TA 5CXAA 1KBCA 2OY2A 4JIJA 2W14A 2X3CA 1YOUA 3N2VA 1JAQA 1XAXA 2OW2A 3G42A 2E2DA 1FBLA 1OO9A 1DTHA 1K7QA 2WO8A 5CUHA 3EWJA 830CA 1IACA 3I7IA 3LJZA 1JH1A 2MZHA 3DPEA 5D1UA 1QJJA 3LE9A 1CGLA 2MLRA 1PWWA 3F18A 1XFZA 1ZP5A 5L7FA 1JJ9A 1AKLA 3ZUKA 3TSKA 1BKCE 4XCTA 4H84A 1JK3A 1MMPA 4AUOA 5JMYA 3O64A 2OZRA 3SHIA 3F15A 1DMTA 4HMAA 2OI0A 3P1VA 3HBUP 1I1IP 4L6TA 1KUHA 3DTKA 3HB2P 1XUDA 2MZIA 1PWUA 1BKCI 3VTGA 1XUCA 2KRJA 5I4OA 3U1RA 4Q1LA 5H8XA 2OW9A 1RMZA 2JT6A 3G5CA 3LIRA 1MMBA 4AYKA 1B8YA 2YUFA 3ELMA 5D1TA 5LABA 4A7BA 1ROSA 1OM8A 3DPFA 3ZVSA 3KMEA 1R55A 4EFSA 2MLSA 2DDYA 5I43A 4H2EA 1Z3JA 1UEAA 1OMJA 2N8RA 1GXDA 3V96B 3EDZA 3DWBA 3HY7A 3KMCA 4AIGA 5I0LA 4GR3A 1KUGA 4G0DA 1G4KA 1IAEA 2A8HA 3P24A 4H82A 3LKAA 4HX3A 1PWPA 1H71P 4CTHA 4G9LA 1CAQA 3WV3A 2CKIA 3Q2GA 1CQRA 1GE7A 2X3BA 4JPAA 2RJQA 1EAKA 1SLMA 1K7IA 3LQ0A 4GR8A 4PKSA 4DV8A 2EROA 1HTDA 1XFYA 3HDBA 1FLSA 1EB6A 2YIGA 3K7LA 2AIGP 2XS3A 3BA0A 2DW1A 3ZXHA 4FVLA 3DTIA 3NX7A 3USNA 2OY4A 3EDGA 5CZMA 1ATLA 1JAOA 2OVXA 2L0RA 2Z2DA 4XBHA 1KUKA 3HBVP 4XM8A 2E3XA 4QKZA 2FV9A 1Y8JA 3LK8A 1SATA 4R3VA 1L6JA 3DTEA 1GO8P 3RTTA 1KUIA 1ZVXA 1G49A 1USNA 4DPEA 3DSLA 4PKRA 2O36A 1JANA 1ASTA 4ILWD 4PKVA 4A3WA 2DW2A 1BIWA 3KRYA 2Y6CA 5L79A 1OM6A 4XM7A 2OXWA 5I12A 3O2XA 3EHYA 2ERQA 1R1IA 1SRPA 4PKUA 2X3AA 2YB9A 2OVZA 1BZSA 4WF6A 4FU4A 4IJOA 4ON1A 4JQGA 3DL1A 3HY9A
chains in the Genus database with same CATH topology
3AIGA 1G9KA 1D8FA 3B2ZA 2SRTA 3OHLA 1UTTA 1A86A 1CGEA 3LJGA 3LMCA 1OS2A 2K9CA 2AYKA 2W13A 3GBOA 4WKEA 2JT5A 1JAPA 1B3DA 1R1HA 4WKIA 2MZEA 2XS4A 1G05A 4GWMA 1C7KA 3L0TA 4XM6A 2O3EA 1BQQM 3F1AA 1QUAA 1GE6A 1XFVA 1XURA 3KEJA 3HDAP 3I7GA 1SU3A 3HYGA 5B5OA 1G12A 4H76A 966CA 1ND1A 4L7AA 1UMTA 3Q2HA 2W12A 1MMRA 1EUBA 1FM1A 3LJTA 1SMPA 2WO9A 5BOTA 3TT4A 2POJA 1C3IA 1GKDA 4DF9A 2DW0A 3LILA 3VI1A 4JA1A 2CLTA 2JNPA 4L63A 1BUVM 2J0TA 5D7WA 2I47A 1IAAA 1GKCA 3KEKA 5BOYA 1HY7A 2J83A 3LUNA 4FXYP 1QJIA 3EHXA 1BM6A 1XFXA 1CGFA 3KWVC 1HFSA 3KECA 1AYKA 4JP4A 3B92A 1UTZA 4DD8A 1HOVA 1HV5A 1CK7A 2OW1A 1D8MA 1YQYA 3MA2A 5BPAA 2PJTA 4PKTA 1PWVA 1A85A 1I76A 1KUFA 4J4MA 1Y93A 1IADA 5D2BA 2HU6A 1XFWA 1JIZA 1YCMA 1JKYA 5D1SA 2RJPA 4L19A 1BQOA 3EDHA 1QICA 3EDIA 3CKIA 4IN9A 5I3MA 1JIWP 4H1QA 1ZXCA 4AXQA 1PWQA 2D1NA 2OW0A 1D7XA 1KAPP 1R1JA 1GE5A 2Y6DA 5I2ZA 3N2UA 2D1OA 3K7NA 1S4BP 1BSWA 1MMQA 1Y0VA 4GWNA 2K2GA 1XFUA 1CXVA 2WOAA 3F16A 4ZR5A 3RTSA 4PKWA 3UVCA 1MNCA 2FV5A 4GR0A 3E8RA 4I35A 1ZTQA 4PKQA 3LIKA 1D5JA 2JIHA 4IUWA 2OXZA 1QIBA 1UMSA 3TVCA 3LEAA 2OXUA 2V4BA 1OS9A 1CIZA 1K7GA 4GQLA 4I03A 3OHOA 3LUMA 4H3XA 2USNA 2TCLA 1GO7P 2X7MA 4H30A 2DDFA 4WK7A 4GUYA 1R54A 3F19A 1WNIA 4FXQA 1ZXVA 1HFCA 1BKCA 1BUDA 2JSDA 3L0VA 1QIAA 1SLNA 4WZVA 456CA 1RM8A 3F17A 3AYKA 1OM7A 3TS4A 3DNGA 2QPJA 3WV2A 2W0DA 3LGPA 1IABA 4GF1A 1C8TA 3B8ZA 1IAGA 1J7NA 1O0QA 1Q3AA 1YP1A 1ZS0A 1I73A 5B5PA 2ERPA 2W15A 5D3CA 3WV1A 4H49A 1AF0A 3LQBA 3AYUA 3KHIA 1O0TA 5CXAA 1KBCA 2OY2A 4JIJA 2W14A 2X3CA 1YOUA 3N2VA 1JAQA 2OW2A 3G42A 2E2DA 1FBLA 1OO9A 1DTHA 1K7QA 2WO8A 5CUHA 3EWJA 830CA 1IACA 3I7IA 3LJZA 1JH1A 2MZHA 3DPEA 5D1UA 1QJJA 3LE9A 1CGLA 2MLRA 1PWWA 3F18A 1XFZA 1ZP5A 5L7FA 1JJ9A 1AKLA 3ZUKA 3TSKA 1BKCE 4XCTA 4H84A 1JK3A 1MMPA 4AUOA 5JMYA 3O64A 2OZRA 3SHIA 3F15A 1DMTA 4HMAA 2OI0A 3P1VA 3HBUP 1I1IP 4L6TA 1KUHA 3DTKA 3HB2P 1XUDA 2MZIA 1PWUA 1BKCI 3VTGA 1XUCA 2KRJA 5I4OA 3U1RA 4Q1LA 5H8XA 2OW9A 1RMZA 2JT6A 3G5CA 3LIRA 1MMBA 4AYKA 1B8YA 2YUFA 3ELMA 5D1TA 5LABA 4A7BA 1ROSA 1OM8A 3DPFA 3ZVSA 3KMEA 1R55A 4EFSA 2MLSA 2DDYA 5I43A 4H2EA 1Z3JA 1UEAA 1OMJA 2N8RA 1GXDA 3V96B 3EDZA 3DWBA 3HY7A 3KMCA 4AIGA 5I0LA 4GR3A 1KUGA 4G0DA 1G4KA 1IAEA 2A8HA 3P24A 4H82A 3LKAA 4HX3A 1PWPA 1H71P 4CTHA 4G9LA 1CAQA 3WV3A 2CKIA 3Q2GA 1CQRA 1GE7A 2X3BA 4JPAA 2RJQA 1EAKA 1SLMA 1K7IA 3LQ0A 4GR8A 4PKSA 4DV8A 2EROA 1HTDA 1XFYA 3HDBA 1FLSA 1EB6A 2YIGA 3K7LA 2AIGP 2XS3A 3BA0A 2DW1A 3ZXHA 4FVLA 3DTIA 3NX7A 3USNA 2OY4A 3EDGA 5CZMA 1ATLA 1JAOA 2OVXA 2L0RA 2Z2DA 4XBHA 1KUKA 3HBVP 4XM8A 2E3XA 4QKZA 2FV9A 1Y8JA 3LK8A 1SATA 4R3VA 1L6JA 3DTEA 1GO8P 3RTTA 1KUIA 1ZVXA 1G49A 1USNA 4DPEA 3DSLA 4PKRA 2O36A 1JANA 1ASTA 4ILWD 4PKVA 4A3WA 2DW2A 1BIWA 3KRYA 2Y6CA 5L79A 1OM6A 4XM7A 2OXWA 5I12A 3O2XA 3EHYA 2ERQA 1R1IA 1SRPA 4PKUA 2X3AA 2YB9A 2OVZA 1BZSA 4WF6A 4FU4A 4IJOA 4ON1A 4JQGA 3DL1A 3HY9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AIG A;  1G9K A;  1D8F A;  3B2Z A;  2SRT A;  3OHL A;  1UTT A;  1A86 A;  1CGE A;  3LJG A;  3LMC A;  1OS2 A;  2K9C A;  2AYK A;  2W13 A;  3GBO A;  4WKE A;  2JT5 A;  1JAP A;  1B3D A;  1R1H A;  4WKI A;  2MZE A;  2XS4 A;  1G05 A;  4GWM A;  1C7K A;  3L0T A;  4XM6 A;  2O3E A;  1BQQ M;  3F1A A;  1QUA A;  1GE6 A;  1XFV A;  1XUR A;  3KEJ A;  3HDA P;  3I7G A;  1SU3 A;  3HYG A;  5B5O A;  1G12 A;  4H76 A;  966C A;  1ND1 A;  1UMT A;  3Q2H A;  2W12 A;  1MMR A;  1EUB A;  1FM1 A;  3LJT A;  1SMP A;  2WO9 A;  5BOT A;  3TT4 A;  2POJ A;  1C3I A;  1GKD A;  4DF9 A;  2DW0 A;  3LIL A;  3VI1 A;  4JA1 A;  2CLT A;  2JNP A;  4L63 A;  1BUV M;  2J0T A;  5D7W A;  2I47 A;  1IAA A;  1GKC A;  3KEK A;  5BOY A;  1HY7 A;  2J83 A;  3LUN A;  4FXY P;  1QJI A;  3EHX A;  1BM6 A;  1XFX A;  1CGF A;  3KWV C;  1HFS A;  3KEC A;  1AYK A;  4JP4 A;  3B92 A;  1UTZ A;  4DD8 A;  1HOV A;  1HV5 A;  1CK7 A;  2OW1 A;  1D8M A;  1YQY A;  3MA2 A;  5BPA A;  2PJT A;  4PKT A;  1PWV A;  1A85 A;  1I76 A;  1KUF A;  4J4M A;  1Y93 A;  1IAD A;  5D2B A;  2HU6 A;  1XFW A;  1JIZ A;  1YCM A;  1JKY A;  5D1S A;  2RJP A;  4L19 A;  1BQO A;  3EDH A;  1QIC A;  3EDI A;  3CKI A;  4IN9 A;  5I3M A;  1JIW P;  4H1Q A;  1ZXC A;  4AXQ A;  1PWQ A;  2D1N A;  2OW0 A;  1D7X A;  1KAP P;  1R1J A;  1GE5 A;  2Y6D A;  5I2Z A;  3N2U A;  2D1O A;  3K7N A;  1S4B P;  1BSW A;  1MMQ A;  1Y0V A;  4GWN A;  2K2G A;  1XFU A;  1CXV A;  2WOA A;  3F16 A;  4ZR5 A;  3RTS A;  4PKW A;  3UVC A;  1MNC A;  2FV5 A;  4GR0 A;  3E8R A;  4I35 A;  1ZTQ A;  4PKQ A;  3LIK A;  1D5J A;  2JIH A;  4IUW A;  2OXZ A;  1QIB A;  1UMS A;  3TVC A;  3LEA A;  2OXU A;  2V4B A;  1OS9 A;  1CIZ A;  1K7G A;  4GQL A;  4I03 A;  3OHO A;  3LUM A;  4H3X A;  2USN A;  2TCL A;  1GO7 P;  2X7M A;  4H30 A;  2DDF A;  4WK7 A;  4GUY A;  1R54 A;  3F19 A;  1WNI A;  4FXQ A;  1ZXV A;  1HFC A;  1BKC A;  1BUD A;  2JSD A;  3L0V A;  1QIA A;  1SLN A;  4WZV A;  456C A;  1RM8 A;  3F17 A;  3AYK A;  1OM7 A;  3TS4 A;  3DNG A;  2QPJ A;  3WV2 A;  2W0D A;  3LGP A;  1IAB A;  4GF1 A;  1C8T A;  3B8Z A;  1IAG A;  1J7N A;  1O0Q A;  1Q3A A;  1YP1 A;  1ZS0 A;  1I73 A;  5B5P A;  2ERP A;  2W15 A;  5D3C A;  3WV1 A;  4H49 A;  1AF0 A;  3LQB A;  3AYU A;  3KHI A;  1O0T A;  5CXA A;  1KBC A;  2OY2 A;  4JIJ A;  2W14 A;  2X3C A;  1YOU A;  3N2V A;  1JAQ A;  2OW2 A;  3G42 A;  2E2D A;  1FBL A;  1OO9 A;  1DTH A;  1K7Q A;  2WO8 A;  5CUH A;  3EWJ A;  830C A;  1IAC A;  3I7I A;  3LJZ A;  1JH1 A;  2MZH A;  3DPE A;  5D1U A;  1QJJ A;  3LE9 A;  1CGL A;  2MLR A;  1PWW A;  3F18 A;  1XFZ A;  1ZP5 A;  5L7F A;  1JJ9 A;  1AKL A;  3ZUK A;  3TSK A;  1BKC E;  4XCT A;  4H84 A;  1JK3 A;  1MMP A;  4AUO A;  5JMY A;  3O64 A;  2OZR A;  3SHI A;  3F15 A;  1DMT A;  4HMA A;  2OI0 A;  3P1V A;  1I1I P;  3HBU P;  4L6T A;  1KUH A;  3HB2 P;  1XUD A;  2MZI A;  1PWU A;  1BKC I;  3VTG A;  1XUC A;  2KRJ A;  5I4O A;  3U1R A;  4Q1L A;  5H8X A;  2OW9 A;  1RMZ A;  2JT6 A;  3G5C A;  3LIR A;  1MMB A;  4AYK A;  1B8Y A;  3ELM A;  5D1T A;  5LAB A;  4A7B A;  1ROS A;  1OM8 A;  3DPF A;  3ZVS A;  3KME A;  1R55 A;  4EFS A;  2MLS A;  2DDY A;  5I43 A;  4H2E A;  1Z3J A;  1UEA A;  1OMJ A;  2N8R A;  1GXD A;  3V96 B;  3EDZ A;  3DWB A;  3HY7 A;  3KMC A;  4AIG A;  5I0L A;  4GR3 A;  1KUG A;  4G0D A;  1G4K A;  1IAE A;  2A8H A;  3P24 A;  4H82 A;  3LKA A;  4HX3 A;  1PWP A;  1H71 P;  4CTH A;  4G9L A;  1CAQ A;  3WV3 A;  2CKI A;  3Q2G A;  1CQR A;  1GE7 A;  2X3B A;  4JPA A;  2RJQ A;  1EAK A;  1SLM A;  1K7I A;  3LQ0 A;  4GR8 A;  4PKS A;  4DV8 A;  2ERO A;  1HTD A;  1XFY A;  3HDB A;  1FLS A;  1EB6 A;  2YIG A;  3K7L A;  2AIG P;  2XS3 A;  3BA0 A;  2DW1 A;  3ZXH A;  4FVL A;  3NX7 A;  3USN A;  2OY4 A;  3EDG A;  5CZM A;  1ATL A;  1JAO A;  2OVX A;  2L0R A;  2Z2D A;  4XBH A;  1KUK A;  3HBV P;  4XM8 A;  2E3X A;  4QKZ A;  2FV9 A;  1Y8J A;  3LK8 A;  1SAT A;  4R3V A;  1L6J A;  1GO8 P;  3RTT A;  1KUI A;  1ZVX A;  1G49 A;  1USN A;  4DPE A;  3DSL A;  4PKR A;  2O36 A;  1JAN A;  1AST A;  4ILW D;  4PKV A;  4A3W A;  2DW2 A;  1BIW A;  3KRY A;  2Y6C A;  5L79 A;  1OM6 A;  4XM7 A;  2OXW A;  5I12 A;  3O2X A;  3EHY A;  2ERQ A;  1R1I A;  1SRP A;  4PKU A;  2X3A A;  2YB9 A;  2OVZ A;  1BZS A;  4WF6 A;  4FU4 A;  4IJO A;  4ON1 A;  4JQG A;  3DL1 A;  3HY9 A; 
#chains in the Genus database with same CATH topology
 3AIG A;  1G9K A;  1D8F A;  3B2Z A;  2SRT A;  3OHL A;  1UTT A;  1A86 A;  1CGE A;  3LJG A;  3LMC A;  1OS2 A;  2K9C A;  2AYK A;  2W13 A;  3GBO A;  1OZ9 A;  4WKE A;  2JT5 A;  1JAP A;  1B3D A;  1R1H A;  4WKI A;  2MZE A;  2XS4 A;  1G05 A;  4GWM A;  1C7K A;  3L0T A;  4XM6 A;  2O3E A;  1BQQ M;  3F1A A;  1QUA A;  1GE6 A;  1XFV A;  1XUR A;  3KEJ A;  3HDA P;  1TVI A;  3I7G A;  1SU3 A;  3HYG A;  5B5O A;  1G12 A;  4H76 A;  966C A;  1ND1 A;  4L7A A;  1UMT A;  3Q2H A;  2W12 A;  1MMR A;  1EUB A;  1FM1 A;  3LJT A;  1SMP A;  2WO9 A;  5BOT A;  3TT4 A;  2POJ A;  1C3I A;  1GKD A;  4DF9 A;  2DW0 A;  3LIL A;  3VI1 A;  4JA1 A;  2CLT A;  2JNP A;  4L63 A;  1BUV M;  2J0T A;  5D7W A;  2I47 A;  1IAA A;  1GKC A;  3KEK A;  5BOY A;  1HY7 A;  2J83 A;  3LUN A;  4FXY P;  1QJI A;  3EHX A;  1BM6 A;  1XFX A;  1CGF A;  3KWV C;  1HFS A;  3KEC A;  1AYK A;  4JP4 A;  3B92 A;  1UTZ A;  4DD8 A;  1HOV A;  1HV5 A;  1CK7 A;  2OW1 A;  1D8M A;  1YQY A;  3MA2 A;  5BPA A;  2PJT A;  4PKT A;  1PWV A;  1A85 A;  1I76 A;  1KUF A;  4J4M A;  1Y93 A;  1IAD A;  5D2B A;  2HU6 A;  1XFW A;  1JIZ A;  1YCM A;  1JKY A;  5D1S A;  2RJP A;  4L19 A;  1BQO A;  3EDH A;  1QIC A;  3EDI A;  3CKI A;  4IN9 A;  5I3M A;  1JIW P;  4H1Q A;  1ZXC A;  4AXQ A;  1PWQ A;  2D1N A;  2OW0 A;  1D7X A;  1KAP P;  1R1J A;  1GE5 A;  2Y6D A;  5I2Z A;  3N2U A;  2D1O A;  3K7N A;  1S4B P;  1BSW A;  1MMQ A;  1Y0V A;  4GWN A;  2K2G A;  1XFU A;  1CXV A;  2WOA A;  3F16 A;  4ZR5 A;  1XM5 A;  3RTS A;  4PKW A;  3UVC A;  1MNC A;  2FV5 A;  4GR0 A;  3E8R A;  4I35 A;  1ZTQ A;  4PKQ A;  3LIK A;  1D5J A;  2JIH A;  4IUW A;  2OXZ A;  1QIB A;  1UMS A;  3TVC A;  3LEA A;  2OXU A;  2V4B A;  1OS9 A;  1CIZ A;  1K7G A;  4GQL A;  4I03 A;  3OHO A;  3LUM A;  4H3X A;  2USN A;  2TCL A;  1GO7 P;  2X7M A;  4H30 A;  2DDF A;  4WK7 A;  4GUY A;  1R54 A;  3F19 A;  1WNI A;  4FXQ A;  1ZXV A;  1HFC A;  1BKC A;  1BUD A;  2JSD A;  3L0V A;  1QIA A;  1SLN A;  4WZV A;  456C A;  1RM8 A;  3F17 A;  3AYK A;  1OM7 A;  3TS4 A;  3DNG A;  2QPJ A;  3WV2 A;  2W0D A;  3LGP A;  1IAB A;  4GF1 A;  1C8T A;  3B8Z A;  1IAG A;  1J7N A;  1O0Q A;  1Q3A A;  1YP1 A;  1ZS0 A;  1I73 A;  5B5P A;  2ERP A;  2W15 A;  5D3C A;  3WV1 A;  4H49 A;  1AF0 A;  3LQB A;  3AYU A;  3KHI A;  1O0T A;  5CXA A;  1KBC A;  2OY2 A;  4JIJ A;  2W14 A;  2X3C A;  1YOU A;  3N2V A;  1JAQ A;  1XAX A;  2OW2 A;  3G42 A;  2E2D A;  1FBL A;  1OO9 A;  1DTH A;  1K7Q A;  2WO8 A;  5CUH A;  3EWJ A;  830C A;  1IAC A;  3I7I A;  3LJZ A;  1JH1 A;  2MZH A;  3DPE A;  5D1U A;  1QJJ A;  3LE9 A;  1CGL A;  2MLR A;  1PWW A;  3F18 A;  1XFZ A;  1ZP5 A;  5L7F A;  1JJ9 A;  1AKL A;  3ZUK A;  3TSK A;  1BKC E;  4XCT A;  4H84 A;  1JK3 A;  1MMP A;  4AUO A;  5JMY A;  3O64 A;  2OZR A;  3SHI A;  3F15 A;  1DMT A;  4HMA A;  2OI0 A;  3P1V A;  3HBU P;  1I1I P;  4L6T A;  1KUH A;  3DTK A;  3HB2 P;  1XUD A;  2MZI A;  1PWU A;  1BKC I;  3VTG A;  1XUC A;  2KRJ A;  5I4O A;  3U1R A;  4Q1L A;  5H8X A;  2OW9 A;  1RMZ A;  2JT6 A;  3G5C A;  3LIR A;  1MMB A;  4AYK A;  1B8Y A;  2YUF A;  3ELM A;  5D1T A;  5LAB A;  4A7B A;  1ROS A;  1OM8 A;  3DPF A;  3ZVS A;  3KME A;  1R55 A;  4EFS A;  2MLS A;  2DDY A;  5I43 A;  4H2E A;  1Z3J A;  1UEA A;  1OMJ A;  2N8R A;  1GXD A;  3V96 B;  3EDZ A;  3DWB A;  3HY7 A;  3KMC A;  4AIG A;  5I0L A;  4GR3 A;  1KUG A;  4G0D A;  1G4K A;  1IAE A;  2A8H A;  3P24 A;  4H82 A;  3LKA A;  4HX3 A;  1PWP A;  1H71 P;  4CTH A;  4G9L A;  1CAQ A;  3WV3 A;  2CKI A;  3Q2G A;  1CQR A;  1GE7 A;  2X3B A;  4JPA A;  2RJQ A;  1EAK A;  1SLM A;  1K7I A;  3LQ0 A;  4GR8 A;  4PKS A;  4DV8 A;  2ERO A;  1HTD A;  1XFY A;  3HDB A;  1FLS A;  1EB6 A;  2YIG A;  3K7L A;  2AIG P;  2XS3 A;  3BA0 A;  2DW1 A;  3ZXH A;  4FVL A;  3DTI A;  3NX7 A;  3USN A;  2OY4 A;  3EDG A;  5CZM A;  1ATL A;  1JAO A;  2OVX A;  2L0R A;  2Z2D A;  4XBH A;  1KUK A;  3HBV P;  4XM8 A;  2E3X A;  4QKZ A;  2FV9 A;  1Y8J A;  3LK8 A;  1SAT A;  4R3V A;  1L6J A;  3DTE A;  1GO8 P;  3RTT A;  1KUI A;  1ZVX A;  1G49 A;  1USN A;  4DPE A;  3DSL A;  4PKR A;  2O36 A;  1JAN A;  1AST A;  4ILW D;  4PKV A;  4A3W A;  2DW2 A;  1BIW A;  3KRY A;  2Y6C A;  5L79 A;  1OM6 A;  4XM7 A;  2OXW A;  5I12 A;  3O2X A;  3EHY A;  2ERQ A;  1R1I A;  1SRP A;  4PKU A;  2X3A A;  2YB9 A;  2OVZ A;  1BZS A;  4WF6 A;  4FU4 A;  4IJO A;  4ON1 A;  4JQG A;  3DL1 A;  3HY9 A; 
#chains in the Genus database with same CATH homology
 3AIG A;  1G9K A;  1D8F A;  3B2Z A;  2SRT A;  3OHL A;  1UTT A;  1A86 A;  1CGE A;  3LJG A;  3LMC A;  1OS2 A;  2K9C A;  2AYK A;  2W13 A;  3GBO A;  4WKE A;  2JT5 A;  1JAP A;  1B3D A;  1R1H A;  4WKI A;  2MZE A;  2XS4 A;  1G05 A;  4GWM A;  1C7K A;  3L0T A;  4XM6 A;  2O3E A;  1BQQ M;  3F1A A;  1QUA A;  1GE6 A;  1XFV A;  1XUR A;  3KEJ A;  3HDA P;  3I7G A;  1SU3 A;  3HYG A;  5B5O A;  1G12 A;  4H76 A;  966C A;  1ND1 A;  4L7A A;  1UMT A;  3Q2H A;  2W12 A;  1MMR A;  1EUB A;  1FM1 A;  3LJT A;  1SMP A;  2WO9 A;  5BOT A;  3TT4 A;  2POJ A;  1C3I A;  1GKD A;  4DF9 A;  2DW0 A;  3LIL A;  3VI1 A;  4JA1 A;  2CLT A;  2JNP A;  4L63 A;  1BUV M;  2J0T A;  5D7W A;  2I47 A;  1IAA A;  1GKC A;  3KEK A;  5BOY A;  1HY7 A;  2J83 A;  3LUN A;  4FXY P;  1QJI A;  3EHX A;  1BM6 A;  1XFX A;  1CGF A;  3KWV C;  1HFS A;  3KEC A;  1AYK A;  4JP4 A;  3B92 A;  1UTZ A;  4DD8 A;  1HOV A;  1HV5 A;  1CK7 A;  2OW1 A;  1D8M A;  1YQY A;  3MA2 A;  5BPA A;  2PJT A;  4PKT A;  1PWV A;  1A85 A;  1I76 A;  1KUF A;  4J4M A;  1Y93 A;  1IAD A;  5D2B A;  2HU6 A;  1XFW A;  1JIZ A;  1YCM A;  1JKY A;  5D1S A;  2RJP A;  4L19 A;  1BQO A;  3EDH A;  1QIC A;  3EDI A;  3CKI A;  4IN9 A;  5I3M A;  1JIW P;  4H1Q A;  1ZXC A;  4AXQ A;  1PWQ A;  2D1N A;  2OW0 A;  1D7X A;  1KAP P;  1R1J A;  1GE5 A;  2Y6D A;  5I2Z A;  3N2U A;  2D1O A;  3K7N A;  1S4B P;  1BSW A;  1MMQ A;  1Y0V A;  4GWN A;  2K2G A;  1XFU A;  1CXV A;  2WOA A;  3F16 A;  4ZR5 A;  3RTS A;  4PKW A;  3UVC A;  1MNC A;  2FV5 A;  4GR0 A;  3E8R A;  4I35 A;  1ZTQ A;  4PKQ A;  3LIK A;  1D5J A;  2JIH A;  4IUW A;  2OXZ A;  1QIB A;  1UMS A;  3TVC A;  3LEA A;  2OXU A;  2V4B A;  1OS9 A;  1CIZ A;  1K7G A;  4GQL A;  4I03 A;  3OHO A;  3LUM A;  4H3X A;  2USN A;  2TCL A;  1GO7 P;  2X7M A;  4H30 A;  2DDF A;  4WK7 A;  4GUY A;  1R54 A;  3F19 A;  1WNI A;  4FXQ A;  1ZXV A;  1HFC A;  1BKC A;  1BUD A;  2JSD A;  3L0V A;  1QIA A;  1SLN A;  4WZV A;  456C A;  1RM8 A;  3F17 A;  3AYK A;  1OM7 A;  3TS4 A;  3DNG A;  2QPJ A;  3WV2 A;  2W0D A;  3LGP A;  1IAB A;  4GF1 A;  1C8T A;  3B8Z A;  1IAG A;  1J7N A;  1O0Q A;  1Q3A A;  1YP1 A;  1ZS0 A;  1I73 A;  5B5P A;  2ERP A;  2W15 A;  5D3C A;  3WV1 A;  4H49 A;  1AF0 A;  3LQB A;  3AYU A;  3KHI A;  1O0T A;  5CXA A;  1KBC A;  2OY2 A;  4JIJ A;  2W14 A;  2X3C A;  1YOU A;  3N2V A;  1JAQ A;  2OW2 A;  3G42 A;  2E2D A;  1FBL A;  1OO9 A;  1DTH A;  1K7Q A;  2WO8 A;  5CUH A;  3EWJ A;  830C A;  1IAC A;  3I7I A;  3LJZ A;  1JH1 A;  2MZH A;  3DPE A;  5D1U A;  1QJJ A;  3LE9 A;  1CGL A;  2MLR A;  1PWW A;  3F18 A;  1XFZ A;  1ZP5 A;  5L7F A;  1JJ9 A;  1AKL A;  3ZUK A;  3TSK A;  1BKC E;  4XCT A;  4H84 A;  1JK3 A;  1MMP A;  4AUO A;  5JMY A;  3O64 A;  2OZR A;  3SHI A;  3F15 A;  1DMT A;  4HMA A;  2OI0 A;  3P1V A;  3HBU P;  1I1I P;  4L6T A;  1KUH A;  3DTK A;  3HB2 P;  1XUD A;  2MZI A;  1PWU A;  1BKC I;  3VTG A;  1XUC A;  2KRJ A;  5I4O A;  3U1R A;  4Q1L A;  5H8X A;  2OW9 A;  1RMZ A;  2JT6 A;  3G5C A;  3LIR A;  1MMB A;  4AYK A;  1B8Y A;  2YUF A;  3ELM A;  5D1T A;  5LAB A;  4A7B A;  1ROS A;  1OM8 A;  3DPF A;  3ZVS A;  3KME A;  1R55 A;  4EFS A;  2MLS A;  2DDY A;  5I43 A;  4H2E A;  1Z3J A;  1UEA A;  1OMJ A;  2N8R A;  1GXD A;  3V96 B;  3EDZ A;  3DWB A;  3HY7 A;  3KMC A;  4AIG A;  5I0L A;  4GR3 A;  1KUG A;  4G0D A;  1G4K A;  1IAE A;  2A8H A;  3P24 A;  4H82 A;  3LKA A;  4HX3 A;  1PWP A;  1H71 P;  4CTH A;  4G9L A;  1CAQ A;  3WV3 A;  2CKI A;  3Q2G A;  1CQR A;  1GE7 A;  2X3B A;  4JPA A;  2RJQ A;  1EAK A;  1SLM A;  1K7I A;  3LQ0 A;  4GR8 A;  4PKS A;  4DV8 A;  2ERO A;  1HTD A;  1XFY A;  3HDB A;  1FLS A;  1EB6 A;  2YIG A;  3K7L A;  2AIG P;  2XS3 A;  3BA0 A;  2DW1 A;  3ZXH A;  4FVL A;  3DTI A;  3NX7 A;  3USN A;  2OY4 A;  3EDG A;  5CZM A;  1ATL A;  1JAO A;  2OVX A;  2L0R A;  2Z2D A;  4XBH A;  1KUK A;  3HBV P;  4XM8 A;  2E3X A;  4QKZ A;  2FV9 A;  1Y8J A;  3LK8 A;  1SAT A;  4R3V A;  1L6J A;  3DTE A;  1GO8 P;  3RTT A;  1KUI A;  1ZVX A;  1G49 A;  1USN A;  4DPE A;  3DSL A;  4PKR A;  2O36 A;  1JAN A;  1AST A;  4ILW D;  4PKV A;  4A3W A;  2DW2 A;  1BIW A;  3KRY A;  2Y6C A;  5L79 A;  1OM6 A;  4XM7 A;  2OXW A;  5I12 A;  3O2X A;  3EHY A;  2ERQ A;  1R1I A;  1SRP A;  4PKU A;  2X3A A;  2YB9 A;  2OVZ A;  1BZS A;  4WF6 A;  4FU4 A;  4IJO A;  4ON1 A;  4JQG A;  3DL1 A;  3HY9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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