3EHXA

Crystal structure of the catalytic domain of human mmp12 complexed with the inhibitor (r)-2-(biphenyl-4-ylsulfonamido)-4-methylpentanoic acid
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
158
structure length
158
Chain Sequence
GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Biotin-tagged probes for MMP expression and activation: design, synthesis, and binding properties
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Macrophage metalloelastase
total genus 45
structure length 158
sequence length 158
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2008-09-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3ehxA00
4FXYP 5BOTA 2X7MA 1CGLA 1PWVA 1OS9A 1JIZA 5D2BA 3MA2A 3DNGA 3LGPA 1PWQA 2W0DA 1QICA 4JIJA 3HBUP 2Y6CA 3B2ZA 1K7GA 1BUDA 5LABA 3LJTA 2WO9A 1FBLA 1GE7A 1JIWP 830CA 1SLNA 2OXWA 4H30A 1S4BP 3EHYA 4DF9A 4PKSA 1HY7A 2OW0A 1MMPA 3TVCA 2ERQA 1XUDA 2MLSA 1UTTA 3KMCA 3AIGA 2XS4A 3DSLA 1HFCA 1XUCA 5D1TA 1D7XA 1CGEA 2HU6A 2J0TA 4XBHA 1ASTA 4PKRA 3AYKA 1OS2A 4H1QA 5I2ZA 4H3XA 3LQBA 3DPFA 2I47A 2E2DA 2OW9A 4QKZA 2CLTA 4L6TA 3LEAA 3HDAP 1CAQA 3TS4A 1CXVA 4JP4A 3V96B 1JJ9A 5D3CA 3USNA 4CTHA 4G9LA 1HTDA 1KUIA 3LILA 4H82A 1CIZA 4EFSA 3LMCA 1XFXA 1BUVM 3F15A 5I43A 3G42A 2D1NA 1HFSA 3F17A 1KAPP 4JA1A 1G12A 1ROSA 1I76A 3OHLA 1GE6A 1FM1A 3DWBA 3EDIA 3KMEA 4GQLA 1YCMA 2Z2DA 1UEAA 4XM6A 3LQ0A 4DD8A 3LIRA 1SU3A 1L6JA 4GUYA 3KECA 5BOYA 2AYKA 1HV5A 1ATLA 4XM8A 1HOVA 1EB6A 2MZHA 1R55A 1R1IA 1FLSA 4WKIA 3UVCA 3GBOA 1ND1A 1CK7A 4JPAA 2DW2A 2D1OA 4FXQA 2YIGA 4IN9A 1QIAA 4H84A 2W14A 3EDHA 1Q3AA 3F18A 5D1SA 2W12A 2OVXA 2JT6A 4H49A 4A7BA 3NX7A 2JSDA 1QIBA 1AYKA 1R54A 4WZVA 2X3BA 1BKCE 3WV1A 3WV2A 4I03A 3LE9A 3F16A 1GE5A 1D5JA 5H8XA 1BSWA 3P24A 5CUHA 4AUOA 3B92A 4GR8A 1MMBA 4ILWD 3I7IA 2DDYA 1BKCA 3TSKA 1R1JA 2K9CA 1B3DA 4A3WA 2OZRA 2K2GA 2Y6DA 3EDGA 2RJQA 4PKUA 1XFWA 4AIGA 2POJA 1USNA 3ELMA 5I0LA 1UMSA 1OO9A 3LK8A 5BPAA 1D8FA 2J83A 4R3VA 1QJJA 1JAPA 1J7NA 1MMQA 1KUKA 2W15A 2SRTA 3HY9A 1C8TA 2XS3A 1SLMA 3ZUKA 1OMJA 2QPJA 3LKAA 1GXDA 1QUAA 1JH1A 1G49A 1XFVA 5JMYA 2JNPA 3F19A 3EHXA 3AYUA 1QJIA 3VI1A 3HB2P 3P1VA 1I73A 4WKEA 4H76A 4JQGA 1O0TA 3N2UA 1H71P 1A85A 3DPEA 1JK3A 1IABA 2KRJA 1I1IP 3L0VA 2OW1A 1OM7A 4IJOA 4WF6A 2TCLA 3OHOA 3O2XA 2DW1A 2OI0A 4XCTA 4L63A 1GO8P 4XM7A 1KUGA 3LUNA 3LJGA 1IAEA 2OVZA 3EDZA 2PJTA 1GKDA 1G4KA 2DW0A 1G9KA 2W13A 3N2VA 2O3EA 1SMPA 1UMTA 1YOUA 1Y0VA 1D8MA 1RM8A 2JIHA 1IAAA 2MZEA 5B5PA 1DMTA 1MMRA 2YB9A 4GWNA 4GWMA 5D1UA 3U1RA 3KWVC 4I35A 4FU4A 3Q2HA 3LIKA 1AKLA 3RTSA 2O36A 1XURA 3EWJA 4FVLA 1BM6A 1KUFA 1ZXCA 4GR0A 1AF0A 4GR3A 4ZR5A 4HX3A 1BZSA 2RJPA 1UTZA 1XFYA 2FV5A 1BQOA 1ZVXA 3K7NA 3SHIA 5CXAA 2OY4A 1MNCA 1IACA 4AYKA 4HMAA 3VTGA 5I4OA 2MZIA 1RMZA 2AIGP 3HBVP 2V4BA 3ZXHA 1YP1A 1ZP5A 3TT4A 4PKTA 2ERPA 1XFZA 4H2EA 1SRPA 3BA0A 5D7WA 1K7IA 2E3XA 5L7FA 1JAQA 4GF1A 3LJZA 1GKCA 1EUBA 5B5OA 4L19A 456CA 1K7QA 1O0QA 3L0TA 1OM8A 1ZS0A 4IUWA 1JKYA 3O64A 1B8YA 5I12A 3K7LA 1C7KA 2OXUA 2MLRA 2A8HA 1PWPA 1YQYA 1WNIA 2FV9A 2OXZA 3HDBA 1XFUA 3KEKA 1KBCA 1JANA 1R1HA 4J4MA 1BKCI 3HY7A 2EROA 2X3CA 2WO8A 5I3MA 3B8ZA 3E8RA 966CA 1BIWA 1Z3JA 3KEJA 4PKWA 4PKQA 1IAGA 1KUHA 2OY2A 4ON1A 2JT5A 1CQRA 1PWUA 4PKVA 1BQQM 2CKIA 5CZMA 1A86A 3CKIA 4G0DA 3I7GA 1Y8JA 3KRYA 4DV8A 1ZXVA 2N8RA 2X3AA 3F1AA 4WK7A 3WV3A 1JAOA 1IADA 3DL1A 2L0RA 1G05A 5L79A 3LUMA 4Q1LA 1Y93A 3Q2GA 4DPEA 2DDFA 2USNA 1SATA 3RTTA 1GO7P 3ZVSA 3HYGA 1DTHA 2OW2A 1PWWA 1CGFA 3KHIA 4AXQA 2WOAA 1C3IA 3G5CA 1ZTQA 1OM6A 1EAKA
chains in the Genus database with same CATH superfamily
4FXYP 5BOTA 2X7MA 1CGLA 1PWVA 1OS9A 1JIZA 5D2BA 3MA2A 3DNGA 3LGPA 1PWQA 2W0DA 1QICA 4JIJA 3HBUP 2Y6CA 3B2ZA 1K7GA 1BUDA 5LABA 3LJTA 2WO9A 1FBLA 1GE7A 1JIWP 830CA 1SLNA 2OXWA 4H30A 1S4BP 3EHYA 4DF9A 4PKSA 1HY7A 2OW0A 1MMPA 3TVCA 2ERQA 1XUDA 2MLSA 1UTTA 3KMCA 3AIGA 2XS4A 3DSLA 1HFCA 1XUCA 5D1TA 1D7XA 1CGEA 2HU6A 2J0TA 4XBHA 1ASTA 4PKRA 3AYKA 1OS2A 4H1QA 5I2ZA 4H3XA 3LQBA 3DPFA 2I47A 2E2DA 2OW9A 4QKZA 2CLTA 4L6TA 3LEAA 3HDAP 1CAQA 3TS4A 1CXVA 4JP4A 3V96B 1JJ9A 5D3CA 3USNA 4CTHA 4G9LA 1HTDA 1KUIA 3LILA 4H82A 1CIZA 4EFSA 3LMCA 1XFXA 1BUVM 3F15A 5I43A 3G42A 2D1NA 1HFSA 3F17A 1KAPP 4JA1A 1G12A 1ROSA 1I76A 3OHLA 1GE6A 1FM1A 3DWBA 3EDIA 3KMEA 4GQLA 1YCMA 2Z2DA 1UEAA 3DTEA 4XM6A 3LQ0A 4DD8A 3LIRA 1SU3A 1L6JA 4GUYA 3KECA 5BOYA 2AYKA 1HV5A 1ATLA 4XM8A 1HOVA 1EB6A 2MZHA 1R55A 1R1IA 1FLSA 4WKIA 3UVCA 3GBOA 1ND1A 1CK7A 4JPAA 2DW2A 2D1OA 3DTKA 4FXQA 2YIGA 4IN9A 1QIAA 4H84A 2W14A 3EDHA 1Q3AA 3F18A 5D1SA 2W12A 2OVXA 2JT6A 4H49A 4A7BA 3NX7A 2JSDA 1QIBA 1AYKA 1R54A 4WZVA 2X3BA 1OZ9A 1BKCE 3WV1A 3WV2A 4I03A 3LE9A 3F16A 1GE5A 1D5JA 5H8XA 1BSWA 3P24A 5CUHA 4AUOA 3B92A 4GR8A 1MMBA 4ILWD 3I7IA 2DDYA 1BKCA 3TSKA 1R1JA 1XAXA 2K9CA 1B3DA 4A3WA 2OZRA 2K2GA 2Y6DA 3EDGA 2RJQA 4PKUA 1XFWA 4AIGA 2POJA 1USNA 3ELMA 5I0LA 1UMSA 1OO9A 3LK8A 5BPAA 1D8FA 2J83A 4R3VA 1QJJA 1JAPA 1J7NA 1MMQA 1KUKA 2W15A 2SRTA 3HY9A 1C8TA 2XS3A 1SLMA 3ZUKA 1OMJA 2QPJA 3LKAA 1GXDA 1QUAA 1JH1A 1G49A 1XFVA 5JMYA 2JNPA 3F19A 3EHXA 3AYUA 1QJIA 3VI1A 3HB2P 3P1VA 1I73A 4WKEA 4H76A 4JQGA 1O0TA 3N2UA 1H71P 4L7AA 1A85A 3DPEA 1JK3A 1IABA 2KRJA 1I1IP 3L0VA 2OW1A 2YUFA 1OM7A 4IJOA 4WF6A 2TCLA 3OHOA 3O2XA 2DW1A 2OI0A 4XCTA 4L63A 1GO8P 4XM7A 1KUGA 3LUNA 3LJGA 1IAEA 2OVZA 3EDZA 2PJTA 1GKDA 1G4KA 2DW0A 1G9KA 2W13A 3N2VA 2O3EA 1SMPA 1UMTA 1YOUA 1Y0VA 1D8MA 1RM8A 2JIHA 1IAAA 2MZEA 5B5PA 1DMTA 1MMRA 2YB9A 4GWNA 4GWMA 5D1UA 3U1RA 3KWVC 4I35A 4FU4A 3Q2HA 3LIKA 1AKLA 3RTSA 1XM5A 2O36A 1XURA 3EWJA 4FVLA 1TVIA 1BM6A 1KUFA 1ZXCA 4GR0A 1AF0A 4GR3A 4ZR5A 4HX3A 1BZSA 2RJPA 1UTZA 1XFYA 2FV5A 1BQOA 1ZVXA 3K7NA 3SHIA 5CXAA 2OY4A 1MNCA 1IACA 4AYKA 4HMAA 3VTGA 5I4OA 2MZIA 1RMZA 2AIGP 3HBVP 2V4BA 3ZXHA 1YP1A 1ZP5A 3TT4A 4PKTA 2ERPA 1XFZA 4H2EA 1SRPA 3BA0A 5D7WA 1K7IA 2E3XA 5L7FA 1JAQA 4GF1A 3LJZA 1GKCA 1EUBA 5B5OA 4L19A 456CA 1K7QA 1O0QA 3L0TA 1OM8A 1ZS0A 4IUWA 1JKYA 3O64A 1B8YA 5I12A 3K7LA 1C7KA 2OXUA 2MLRA 2A8HA 1PWPA 1YQYA 1WNIA 2FV9A 2OXZA 3HDBA 1XFUA 3KEKA 1KBCA 1JANA 1R1HA 4J4MA 1BKCI 3HY7A 2EROA 2X3CA 2WO8A 5I3MA 3B8ZA 3E8RA 966CA 1BIWA 1Z3JA 3KEJA 4PKWA 4PKQA 1IAGA 1KUHA 2OY2A 4ON1A 2JT5A 1CQRA 1PWUA 4PKVA 1BQQM 2CKIA 5CZMA 1A86A 3CKIA 4G0DA 3I7GA 1Y8JA 3KRYA 4DV8A 1ZXVA 2N8RA 2X3AA 3F1AA 4WK7A 3WV3A 1JAOA 1IADA 3DL1A 2L0RA 1G05A 5L79A 3LUMA 4Q1LA 1Y93A 3Q2GA 4DPEA 2DDFA 2USNA 1SATA 3RTTA 1GO7P 3ZVSA 3HYGA 1DTHA 2OW2A 1PWWA 1CGFA 3KHIA 4AXQA 2WOAA 1C3IA 3DTIA 3G5CA 1ZTQA 1OM6A 1EAKA
chains in the Genus database with same CATH topology
4FXYP 5BOTA 2X7MA 1CGLA 1PWVA 1OS9A 1JIZA 5D2BA 3MA2A 3DNGA 3LGPA 1PWQA 2W0DA 1QICA 4JIJA 3HBUP 2Y6CA 3B2ZA 1K7GA 1BUDA 5LABA 3LJTA 2WO9A 1FBLA 1GE7A 1JIWP 830CA 1SLNA 2OXWA 4H30A 1S4BP 3EHYA 4DF9A 4PKSA 1HY7A 2OW0A 1MMPA 3TVCA 2ERQA 1XUDA 2MLSA 1UTTA 3KMCA 3AIGA 2XS4A 3DSLA 1HFCA 1XUCA 5D1TA 1D7XA 1CGEA 2HU6A 2J0TA 4XBHA 1ASTA 4PKRA 3AYKA 1OS2A 4H1QA 5I2ZA 4H3XA 3LQBA 3DPFA 2I47A 2E2DA 2OW9A 4QKZA 2CLTA 4L6TA 3LEAA 3HDAP 1CAQA 3TS4A 1CXVA 4JP4A 3V96B 1JJ9A 5D3CA 3USNA 4CTHA 4G9LA 1HTDA 1KUIA 3LILA 4H82A 1CIZA 4EFSA 3LMCA 1XFXA 1BUVM 3F15A 5I43A 3G42A 2D1NA 1HFSA 3F17A 1KAPP 4JA1A 1G12A 1ROSA 1I76A 3OHLA 1GE6A 1FM1A 3DWBA 3EDIA 3KMEA 4GQLA 1YCMA 2Z2DA 1UEAA 3DTEA 4XM6A 3LQ0A 4DD8A 3LIRA 1SU3A 1L6JA 4GUYA 3KECA 5BOYA 2AYKA 1HV5A 1ATLA 4XM8A 1HOVA 1EB6A 2MZHA 1R55A 1R1IA 1FLSA 4WKIA 3UVCA 3GBOA 1ND1A 1CK7A 4JPAA 2DW2A 2D1OA 3DTKA 4FXQA 2YIGA 4IN9A 1QIAA 4H84A 2W14A 3EDHA 1Q3AA 3F18A 5D1SA 2W12A 2OVXA 2JT6A 4H49A 4A7BA 3NX7A 2JSDA 1QIBA 1AYKA 1R54A 4WZVA 2X3BA 1BKCE 3WV1A 3WV2A 4I03A 3LE9A 3F16A 1GE5A 1D5JA 5H8XA 1BSWA 3P24A 5CUHA 4AUOA 3B92A 4GR8A 1MMBA 4ILWD 3I7IA 2DDYA 1BKCA 3TSKA 1R1JA 2K9CA 1B3DA 4A3WA 2OZRA 2K2GA 2Y6DA 3EDGA 2RJQA 4PKUA 1XFWA 4AIGA 2POJA 1USNA 3ELMA 5I0LA 1UMSA 1OO9A 3LK8A 5BPAA 1D8FA 2J83A 4R3VA 1QJJA 1JAPA 1J7NA 1MMQA 1KUKA 2W15A 2SRTA 3HY9A 1C8TA 2XS3A 1SLMA 3ZUKA 1OMJA 2QPJA 3LKAA 1GXDA 1QUAA 1JH1A 1G49A 1XFVA 5JMYA 2JNPA 3F19A 3EHXA 3AYUA 1QJIA 3VI1A 3HB2P 3P1VA 1I73A 4WKEA 4H76A 4JQGA 1O0TA 3N2UA 1H71P 4L7AA 1A85A 3DPEA 1JK3A 1IABA 2KRJA 1I1IP 3L0VA 2OW1A 2YUFA 1OM7A 4IJOA 4WF6A 2TCLA 3OHOA 3O2XA 2DW1A 2OI0A 4XCTA 4L63A 1GO8P 4XM7A 1KUGA 3LUNA 3LJGA 1IAEA 2OVZA 3EDZA 2PJTA 1GKDA 1G4KA 2DW0A 1G9KA 2W13A 3N2VA 2O3EA 1SMPA 1UMTA 1YOUA 1Y0VA 1D8MA 1RM8A 2JIHA 1IAAA 2MZEA 5B5PA 1DMTA 1MMRA 2YB9A 4GWNA 4GWMA 5D1UA 3U1RA 3KWVC 4I35A 4FU4A 3Q2HA 3LIKA 1AKLA 3RTSA 2O36A 1XURA 3EWJA 4FVLA 1BM6A 1KUFA 1ZXCA 4GR0A 1AF0A 4GR3A 4ZR5A 4HX3A 1BZSA 2RJPA 1UTZA 1XFYA 2FV5A 1BQOA 1ZVXA 3K7NA 3SHIA 5CXAA 2OY4A 1MNCA 1IACA 4AYKA 4HMAA 3VTGA 5I4OA 2MZIA 1RMZA 2AIGP 3HBVP 2V4BA 3ZXHA 1YP1A 1ZP5A 3TT4A 4PKTA 2ERPA 1XFZA 4H2EA 1SRPA 3BA0A 5D7WA 1K7IA 2E3XA 5L7FA 1JAQA 4GF1A 3LJZA 1GKCA 1EUBA 5B5OA 4L19A 456CA 1K7QA 1O0QA 3L0TA 1OM8A 1ZS0A 4IUWA 1JKYA 3O64A 1B8YA 5I12A 3K7LA 1C7KA 2OXUA 2MLRA 2A8HA 1PWPA 1YQYA 1WNIA 2FV9A 2OXZA 3HDBA 1XFUA 3KEKA 1KBCA 1JANA 1R1HA 4J4MA 1BKCI 3HY7A 2EROA 2X3CA 2WO8A 5I3MA 3B8ZA 3E8RA 966CA 1BIWA 1Z3JA 3KEJA 4PKWA 4PKQA 1IAGA 1KUHA 2OY2A 4ON1A 2JT5A 1CQRA 1PWUA 4PKVA 1BQQM 2CKIA 5CZMA 1A86A 3CKIA 4G0DA 3I7GA 1Y8JA 3KRYA 4DV8A 1ZXVA 2N8RA 2X3AA 3F1AA 4WK7A 3WV3A 1JAOA 1IADA 3DL1A 2L0RA 1G05A 5L79A 3LUMA 4Q1LA 1Y93A 3Q2GA 4DPEA 2DDFA 2USNA 1SATA 3RTTA 1GO7P 3ZVSA 3HYGA 1DTHA 2OW2A 1PWWA 1CGFA 3KHIA 4AXQA 2WOAA 1C3IA 3DTIA 3G5CA 1ZTQA 1OM6A 1EAKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FXY P;  5BOT A;  2X7M A;  1CGL A;  1PWV A;  1OS9 A;  1JIZ A;  5D2B A;  3MA2 A;  3DNG A;  3LGP A;  1PWQ A;  2W0D A;  1QIC A;  4JIJ A;  3HBU P;  2Y6C A;  3B2Z A;  1K7G A;  1BUD A;  5LAB A;  3LJT A;  2WO9 A;  1FBL A;  1GE7 A;  1JIW P;  830C A;  1SLN A;  2OXW A;  4H30 A;  1S4B P;  3EHY A;  4DF9 A;  4PKS A;  1HY7 A;  2OW0 A;  1MMP A;  3TVC A;  2ERQ A;  1XUD A;  2MLS A;  1UTT A;  3KMC A;  3AIG A;  2XS4 A;  3DSL A;  1HFC A;  1XUC A;  5D1T A;  1D7X A;  1CGE A;  2HU6 A;  2J0T A;  4XBH A;  1AST A;  4PKR A;  3AYK A;  1OS2 A;  4H1Q A;  5I2Z A;  4H3X A;  3LQB A;  3DPF A;  2I47 A;  2E2D A;  2OW9 A;  4QKZ A;  2CLT A;  4L6T A;  3LEA A;  3HDA P;  1CAQ A;  3TS4 A;  1CXV A;  4JP4 A;  3V96 B;  1JJ9 A;  5D3C A;  3USN A;  4CTH A;  4G9L A;  1HTD A;  1KUI A;  3LIL A;  4H82 A;  1CIZ A;  4EFS A;  3LMC A;  1XFX A;  1BUV M;  3F15 A;  5I43 A;  3G42 A;  2D1N A;  1HFS A;  3F17 A;  1KAP P;  4JA1 A;  1G12 A;  1ROS A;  1I76 A;  3OHL A;  1GE6 A;  1FM1 A;  3DWB A;  3EDI A;  3KME A;  4GQL A;  1YCM A;  2Z2D A;  1UEA A;  4XM6 A;  3LQ0 A;  4DD8 A;  3LIR A;  1SU3 A;  1L6J A;  4GUY A;  3KEC A;  5BOY A;  2AYK A;  1HV5 A;  1ATL A;  4XM8 A;  1HOV A;  1EB6 A;  2MZH A;  1R55 A;  1R1I A;  1FLS A;  4WKI A;  3UVC A;  3GBO A;  1ND1 A;  1CK7 A;  4JPA A;  2DW2 A;  2D1O A;  4FXQ A;  2YIG A;  4IN9 A;  1QIA A;  4H84 A;  2W14 A;  3EDH A;  1Q3A A;  3F18 A;  5D1S A;  2W12 A;  2OVX A;  2JT6 A;  4H49 A;  4A7B A;  3NX7 A;  2JSD A;  1QIB A;  1AYK A;  1R54 A;  4WZV A;  2X3B A;  1BKC E;  3WV1 A;  3WV2 A;  4I03 A;  3LE9 A;  3F16 A;  1GE5 A;  1D5J A;  5H8X A;  1BSW A;  3P24 A;  5CUH A;  4AUO A;  3B92 A;  4GR8 A;  1MMB A;  4ILW D;  3I7I A;  2DDY A;  1BKC A;  3TSK A;  1R1J A;  2K9C A;  1B3D A;  4A3W A;  2OZR A;  2K2G A;  2Y6D A;  3EDG A;  2RJQ A;  4PKU A;  1XFW A;  4AIG A;  2POJ A;  1USN A;  3ELM A;  5I0L A;  1UMS A;  1OO9 A;  3LK8 A;  5BPA A;  1D8F A;  2J83 A;  4R3V A;  1QJJ A;  1JAP A;  1J7N A;  1MMQ A;  1KUK A;  2W15 A;  2SRT A;  3HY9 A;  1C8T A;  2XS3 A;  1SLM A;  3ZUK A;  1OMJ A;  2QPJ A;  3LKA A;  1GXD A;  1QUA A;  1JH1 A;  1G49 A;  1XFV A;  5JMY A;  2JNP A;  3F19 A;  3EHX A;  3AYU A;  1QJI A;  3VI1 A;  3HB2 P;  3P1V A;  1I73 A;  4WKE A;  4H76 A;  4JQG A;  1O0T A;  3N2U A;  1H71 P;  1A85 A;  3DPE A;  1JK3 A;  1IAB A;  2KRJ A;  1I1I P;  3L0V A;  2OW1 A;  1OM7 A;  4IJO A;  4WF6 A;  2TCL A;  3OHO A;  3O2X A;  2DW1 A;  2OI0 A;  4XCT A;  4L63 A;  1GO8 P;  4XM7 A;  1KUG A;  3LUN A;  3LJG A;  1IAE A;  2OVZ A;  3EDZ A;  2PJT A;  1GKD A;  1G4K A;  2DW0 A;  1G9K A;  2W13 A;  3N2V A;  2O3E A;  1SMP A;  1UMT A;  1YOU A;  1Y0V A;  1D8M A;  1RM8 A;  2JIH A;  1IAA A;  2MZE A;  5B5P A;  1DMT A;  1MMR A;  2YB9 A;  4GWN A;  4GWM A;  5D1U A;  3U1R A;  3KWV C;  4I35 A;  4FU4 A;  3Q2H A;  3LIK A;  1AKL A;  3RTS A;  2O36 A;  1XUR A;  3EWJ A;  4FVL A;  1BM6 A;  1KUF A;  1ZXC A;  4GR0 A;  1AF0 A;  4GR3 A;  4ZR5 A;  4HX3 A;  1BZS A;  2RJP A;  1UTZ A;  1XFY A;  2FV5 A;  1BQO A;  1ZVX A;  3K7N A;  3SHI A;  5CXA A;  2OY4 A;  1MNC A;  1IAC A;  4AYK A;  4HMA A;  3VTG A;  5I4O A;  2MZI A;  1RMZ A;  2AIG P;  3HBV P;  2V4B A;  3ZXH A;  1YP1 A;  1ZP5 A;  3TT4 A;  4PKT A;  2ERP A;  1XFZ A;  4H2E A;  1SRP A;  3BA0 A;  5D7W A;  1K7I A;  2E3X A;  5L7F A;  1JAQ A;  4GF1 A;  3LJZ A;  1GKC A;  1EUB A;  5B5O A;  4L19 A;  456C A;  1K7Q A;  1O0Q A;  3L0T A;  1OM8 A;  1ZS0 A;  4IUW A;  1JKY A;  3O64 A;  1B8Y A;  5I12 A;  3K7L A;  1C7K A;  2OXU A;  2MLR A;  2A8H A;  1PWP A;  1YQY A;  1WNI A;  2FV9 A;  2OXZ A;  3HDB A;  1XFU A;  3KEK A;  1KBC A;  1JAN A;  1R1H A;  4J4M A;  1BKC I;  3HY7 A;  2ERO A;  2X3C A;  2WO8 A;  5I3M A;  3B8Z A;  3E8R A;  966C A;  1BIW A;  1Z3J A;  3KEJ A;  4PKW A;  4PKQ A;  1IAG A;  1KUH A;  2OY2 A;  4ON1 A;  2JT5 A;  1CQR A;  1PWU A;  4PKV A;  1BQQ M;  2CKI A;  5CZM A;  1A86 A;  3CKI A;  4G0D A;  3I7G A;  1Y8J A;  3KRY A;  4DV8 A;  1ZXV A;  2N8R A;  2X3A A;  3F1A A;  4WK7 A;  3WV3 A;  1JAO A;  1IAD A;  3DL1 A;  2L0R A;  1G05 A;  5L79 A;  3LUM A;  4Q1L A;  1Y93 A;  3Q2G A;  4DPE A;  2DDF A;  2USN A;  1SAT A;  3RTT A;  1GO7 P;  3ZVS A;  3HYG A;  1DTH A;  2OW2 A;  1PWW A;  1CGF A;  3KHI A;  4AXQ A;  2WOA A;  1C3I A;  3G5C A;  1ZTQ A;  1OM6 A;  1EAK A; 
#chains in the Genus database with same CATH topology
 4FXY P;  5BOT A;  2X7M A;  1CGL A;  1PWV A;  1OS9 A;  1JIZ A;  5D2B A;  3MA2 A;  3DNG A;  3LGP A;  1PWQ A;  2W0D A;  1QIC A;  4JIJ A;  3HBU P;  2Y6C A;  3B2Z A;  1K7G A;  1BUD A;  5LAB A;  3LJT A;  2WO9 A;  1FBL A;  1GE7 A;  1JIW P;  830C A;  1SLN A;  2OXW A;  4H30 A;  1S4B P;  3EHY A;  4DF9 A;  4PKS A;  1HY7 A;  2OW0 A;  1MMP A;  3TVC A;  2ERQ A;  1XUD A;  2MLS A;  1UTT A;  3KMC A;  3AIG A;  2XS4 A;  3DSL A;  1HFC A;  1XUC A;  5D1T A;  1D7X A;  1CGE A;  2HU6 A;  2J0T A;  4XBH A;  1AST A;  4PKR A;  3AYK A;  1OS2 A;  4H1Q A;  5I2Z A;  4H3X A;  3LQB A;  3DPF A;  2I47 A;  2E2D A;  2OW9 A;  4QKZ A;  2CLT A;  4L6T A;  3LEA A;  3HDA P;  1CAQ A;  3TS4 A;  1CXV A;  4JP4 A;  3V96 B;  1JJ9 A;  5D3C A;  3USN A;  4CTH A;  4G9L A;  1HTD A;  1KUI A;  3LIL A;  4H82 A;  1CIZ A;  4EFS A;  3LMC A;  1XFX A;  1BUV M;  3F15 A;  5I43 A;  3G42 A;  2D1N A;  1HFS A;  3F17 A;  1KAP P;  4JA1 A;  1G12 A;  1ROS A;  1I76 A;  3OHL A;  1GE6 A;  1FM1 A;  3DWB A;  3EDI A;  3KME A;  4GQL A;  1YCM A;  2Z2D A;  1UEA A;  3DTE A;  4XM6 A;  3LQ0 A;  4DD8 A;  3LIR A;  1SU3 A;  1L6J A;  4GUY A;  3KEC A;  5BOY A;  2AYK A;  1HV5 A;  1ATL A;  4XM8 A;  1HOV A;  1EB6 A;  2MZH A;  1R55 A;  1R1I A;  1FLS A;  4WKI A;  3UVC A;  3GBO A;  1ND1 A;  1CK7 A;  4JPA A;  2DW2 A;  2D1O A;  3DTK A;  4FXQ A;  2YIG A;  4IN9 A;  1QIA A;  4H84 A;  2W14 A;  3EDH A;  1Q3A A;  3F18 A;  5D1S A;  2W12 A;  2OVX A;  2JT6 A;  4H49 A;  4A7B A;  3NX7 A;  2JSD A;  1QIB A;  1AYK A;  1R54 A;  4WZV A;  2X3B A;  1OZ9 A;  1BKC E;  3WV1 A;  3WV2 A;  4I03 A;  3LE9 A;  3F16 A;  1GE5 A;  1D5J A;  5H8X A;  1BSW A;  3P24 A;  5CUH A;  4AUO A;  3B92 A;  4GR8 A;  1MMB A;  4ILW D;  3I7I A;  2DDY A;  1BKC A;  3TSK A;  1R1J A;  1XAX A;  2K9C A;  1B3D A;  4A3W A;  2OZR A;  2K2G A;  2Y6D A;  3EDG A;  2RJQ A;  4PKU A;  1XFW A;  4AIG A;  2POJ A;  1USN A;  3ELM A;  5I0L A;  1UMS A;  1OO9 A;  3LK8 A;  5BPA A;  1D8F A;  2J83 A;  4R3V A;  1QJJ A;  1JAP A;  1J7N A;  1MMQ A;  1KUK A;  2W15 A;  2SRT A;  3HY9 A;  1C8T A;  2XS3 A;  1SLM A;  3ZUK A;  1OMJ A;  2QPJ A;  3LKA A;  1GXD A;  1QUA A;  1JH1 A;  1G49 A;  1XFV A;  5JMY A;  2JNP A;  3F19 A;  3EHX A;  3AYU A;  1QJI A;  3VI1 A;  3HB2 P;  3P1V A;  1I73 A;  4WKE A;  4H76 A;  4JQG A;  1O0T A;  3N2U A;  1H71 P;  4L7A A;  1A85 A;  3DPE A;  1JK3 A;  1IAB A;  2KRJ A;  1I1I P;  3L0V A;  2OW1 A;  2YUF A;  1OM7 A;  4IJO A;  4WF6 A;  2TCL A;  3OHO A;  3O2X A;  2DW1 A;  2OI0 A;  4XCT A;  4L63 A;  1GO8 P;  4XM7 A;  1KUG A;  3LUN A;  3LJG A;  1IAE A;  2OVZ A;  3EDZ A;  2PJT A;  1GKD A;  1G4K A;  2DW0 A;  1G9K A;  2W13 A;  3N2V A;  2O3E A;  1SMP A;  1UMT A;  1YOU A;  1Y0V A;  1D8M A;  1RM8 A;  2JIH A;  1IAA A;  2MZE A;  5B5P A;  1DMT A;  1MMR A;  2YB9 A;  4GWN A;  4GWM A;  5D1U A;  3U1R A;  3KWV C;  4I35 A;  4FU4 A;  3Q2H A;  3LIK A;  1AKL A;  3RTS A;  1XM5 A;  2O36 A;  1XUR A;  3EWJ A;  4FVL A;  1TVI A;  1BM6 A;  1KUF A;  1ZXC A;  4GR0 A;  1AF0 A;  4GR3 A;  4ZR5 A;  4HX3 A;  1BZS A;  2RJP A;  1UTZ A;  1XFY A;  2FV5 A;  1BQO A;  1ZVX A;  3K7N A;  3SHI A;  5CXA A;  2OY4 A;  1MNC A;  1IAC A;  4AYK A;  4HMA A;  3VTG A;  5I4O A;  2MZI A;  1RMZ A;  2AIG P;  3HBV P;  2V4B A;  3ZXH A;  1YP1 A;  1ZP5 A;  3TT4 A;  4PKT A;  2ERP A;  1XFZ A;  4H2E A;  1SRP A;  3BA0 A;  5D7W A;  1K7I A;  2E3X A;  5L7F A;  1JAQ A;  4GF1 A;  3LJZ A;  1GKC A;  1EUB A;  5B5O A;  4L19 A;  456C A;  1K7Q A;  1O0Q A;  3L0T A;  1OM8 A;  1ZS0 A;  4IUW A;  1JKY A;  3O64 A;  1B8Y A;  5I12 A;  3K7L A;  1C7K A;  2OXU A;  2MLR A;  2A8H A;  1PWP A;  1YQY A;  1WNI A;  2FV9 A;  2OXZ A;  3HDB A;  1XFU A;  3KEK A;  1KBC A;  1JAN A;  1R1H A;  4J4M A;  1BKC I;  3HY7 A;  2ERO A;  2X3C A;  2WO8 A;  5I3M A;  3B8Z A;  3E8R A;  966C A;  1BIW A;  1Z3J A;  3KEJ A;  4PKW A;  4PKQ A;  1IAG A;  1KUH A;  2OY2 A;  4ON1 A;  2JT5 A;  1CQR A;  1PWU A;  4PKV A;  1BQQ M;  2CKI A;  5CZM A;  1A86 A;  3CKI A;  4G0D A;  3I7G A;  1Y8J A;  3KRY A;  4DV8 A;  1ZXV A;  2N8R A;  2X3A A;  3F1A A;  4WK7 A;  3WV3 A;  1JAO A;  1IAD A;  3DL1 A;  2L0R A;  1G05 A;  5L79 A;  3LUM A;  4Q1L A;  1Y93 A;  3Q2G A;  4DPE A;  2DDF A;  2USN A;  1SAT A;  3RTT A;  1GO7 P;  3ZVS A;  3HYG A;  1DTH A;  2OW2 A;  1PWW A;  1CGF A;  3KHI A;  4AXQ A;  2WOA A;  1C3I A;  3DTI A;  3G5C A;  1ZTQ A;  1OM6 A;  1EAK A; 
#chains in the Genus database with same CATH homology
 4FXY P;  5BOT A;  2X7M A;  1CGL A;  1PWV A;  1OS9 A;  1JIZ A;  5D2B A;  3MA2 A;  3DNG A;  3LGP A;  1PWQ A;  2W0D A;  1QIC A;  4JIJ A;  3HBU P;  2Y6C A;  3B2Z A;  1K7G A;  1BUD A;  5LAB A;  3LJT A;  2WO9 A;  1FBL A;  1GE7 A;  1JIW P;  830C A;  1SLN A;  2OXW A;  4H30 A;  1S4B P;  3EHY A;  4DF9 A;  4PKS A;  1HY7 A;  2OW0 A;  1MMP A;  3TVC A;  2ERQ A;  1XUD A;  2MLS A;  1UTT A;  3KMC A;  3AIG A;  2XS4 A;  3DSL A;  1HFC A;  1XUC A;  5D1T A;  1D7X A;  1CGE A;  2HU6 A;  2J0T A;  4XBH A;  1AST A;  4PKR A;  3AYK A;  1OS2 A;  4H1Q A;  5I2Z A;  4H3X A;  3LQB A;  3DPF A;  2I47 A;  2E2D A;  2OW9 A;  4QKZ A;  2CLT A;  4L6T A;  3LEA A;  3HDA P;  1CAQ A;  3TS4 A;  1CXV A;  4JP4 A;  3V96 B;  1JJ9 A;  5D3C A;  3USN A;  4CTH A;  4G9L A;  1HTD A;  1KUI A;  3LIL A;  4H82 A;  1CIZ A;  4EFS A;  3LMC A;  1XFX A;  1BUV M;  3F15 A;  5I43 A;  3G42 A;  2D1N A;  1HFS A;  3F17 A;  1KAP P;  4JA1 A;  1G12 A;  1ROS A;  1I76 A;  3OHL A;  1GE6 A;  1FM1 A;  3DWB A;  3EDI A;  3KME A;  4GQL A;  1YCM A;  2Z2D A;  1UEA A;  3DTE A;  4XM6 A;  3LQ0 A;  4DD8 A;  3LIR A;  1SU3 A;  1L6J A;  4GUY A;  3KEC A;  5BOY A;  2AYK A;  1HV5 A;  1ATL A;  4XM8 A;  1HOV A;  1EB6 A;  2MZH A;  1R55 A;  1R1I A;  1FLS A;  4WKI A;  3UVC A;  3GBO A;  1ND1 A;  1CK7 A;  4JPA A;  2DW2 A;  2D1O A;  3DTK A;  4FXQ A;  2YIG A;  4IN9 A;  1QIA A;  4H84 A;  2W14 A;  3EDH A;  1Q3A A;  3F18 A;  5D1S A;  2W12 A;  2OVX A;  2JT6 A;  4H49 A;  4A7B A;  3NX7 A;  2JSD A;  1QIB A;  1AYK A;  1R54 A;  4WZV A;  2X3B A;  1BKC E;  3WV1 A;  3WV2 A;  4I03 A;  3LE9 A;  3F16 A;  1GE5 A;  1D5J A;  5H8X A;  1BSW A;  3P24 A;  5CUH A;  4AUO A;  3B92 A;  4GR8 A;  1MMB A;  4ILW D;  3I7I A;  2DDY A;  1BKC A;  3TSK A;  1R1J A;  2K9C A;  1B3D A;  4A3W A;  2OZR A;  2K2G A;  2Y6D A;  3EDG A;  2RJQ A;  4PKU A;  1XFW A;  4AIG A;  2POJ A;  1USN A;  3ELM A;  5I0L A;  1UMS A;  1OO9 A;  3LK8 A;  5BPA A;  1D8F A;  2J83 A;  4R3V A;  1QJJ A;  1JAP A;  1J7N A;  1MMQ A;  1KUK A;  2W15 A;  2SRT A;  3HY9 A;  1C8T A;  2XS3 A;  1SLM A;  3ZUK A;  1OMJ A;  2QPJ A;  3LKA A;  1GXD A;  1QUA A;  1JH1 A;  1G49 A;  1XFV A;  5JMY A;  2JNP A;  3F19 A;  3EHX A;  3AYU A;  1QJI A;  3VI1 A;  3HB2 P;  3P1V A;  1I73 A;  4WKE A;  4H76 A;  4JQG A;  1O0T A;  3N2U A;  1H71 P;  4L7A A;  1A85 A;  3DPE A;  1JK3 A;  1IAB A;  2KRJ A;  1I1I P;  3L0V A;  2OW1 A;  2YUF A;  1OM7 A;  4IJO A;  4WF6 A;  2TCL A;  3OHO A;  3O2X A;  2DW1 A;  2OI0 A;  4XCT A;  4L63 A;  1GO8 P;  4XM7 A;  1KUG A;  3LUN A;  3LJG A;  1IAE A;  2OVZ A;  3EDZ A;  2PJT A;  1GKD A;  1G4K A;  2DW0 A;  1G9K A;  2W13 A;  3N2V A;  2O3E A;  1SMP A;  1UMT A;  1YOU A;  1Y0V A;  1D8M A;  1RM8 A;  2JIH A;  1IAA A;  2MZE A;  5B5P A;  1DMT A;  1MMR A;  2YB9 A;  4GWN A;  4GWM A;  5D1U A;  3U1R A;  3KWV C;  4I35 A;  4FU4 A;  3Q2H A;  3LIK A;  1AKL A;  3RTS A;  2O36 A;  1XUR A;  3EWJ A;  4FVL A;  1BM6 A;  1KUF A;  1ZXC A;  4GR0 A;  1AF0 A;  4GR3 A;  4ZR5 A;  4HX3 A;  1BZS A;  2RJP A;  1UTZ A;  1XFY A;  2FV5 A;  1BQO A;  1ZVX A;  3K7N A;  3SHI A;  5CXA A;  2OY4 A;  1MNC A;  1IAC A;  4AYK A;  4HMA A;  3VTG A;  5I4O A;  2MZI A;  1RMZ A;  2AIG P;  3HBV P;  2V4B A;  3ZXH A;  1YP1 A;  1ZP5 A;  3TT4 A;  4PKT A;  2ERP A;  1XFZ A;  4H2E A;  1SRP A;  3BA0 A;  5D7W A;  1K7I A;  2E3X A;  5L7F A;  1JAQ A;  4GF1 A;  3LJZ A;  1GKC A;  1EUB A;  5B5O A;  4L19 A;  456C A;  1K7Q A;  1O0Q A;  3L0T A;  1OM8 A;  1ZS0 A;  4IUW A;  1JKY A;  3O64 A;  1B8Y A;  5I12 A;  3K7L A;  1C7K A;  2OXU A;  2MLR A;  2A8H A;  1PWP A;  1YQY A;  1WNI A;  2FV9 A;  2OXZ A;  3HDB A;  1XFU A;  3KEK A;  1KBC A;  1JAN A;  1R1H A;  4J4M A;  1BKC I;  3HY7 A;  2ERO A;  2X3C A;  2WO8 A;  5I3M A;  3B8Z A;  3E8R A;  966C A;  1BIW A;  1Z3J A;  3KEJ A;  4PKW A;  4PKQ A;  1IAG A;  1KUH A;  2OY2 A;  4ON1 A;  2JT5 A;  1CQR A;  1PWU A;  4PKV A;  1BQQ M;  2CKI A;  5CZM A;  1A86 A;  3CKI A;  4G0D A;  3I7G A;  1Y8J A;  3KRY A;  4DV8 A;  1ZXV A;  2N8R A;  2X3A A;  3F1A A;  4WK7 A;  3WV3 A;  1JAO A;  1IAD A;  3DL1 A;  2L0R A;  1G05 A;  5L79 A;  3LUM A;  4Q1L A;  1Y93 A;  3Q2G A;  4DPE A;  2DDF A;  2USN A;  1SAT A;  3RTT A;  1GO7 P;  3ZVS A;  3HYG A;  1DTH A;  2OW2 A;  1PWW A;  1CGF A;  3KHI A;  4AXQ A;  2WOA A;  1C3I A;  3DTI A;  3G5C A;  1ZTQ A;  1OM6 A;  1EAK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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