3F16A

Crystal structure of the catalytic domain of human mmp12 complexed with the inhibitor (r)-n-(3-hydroxy-1-nitroso-1-oxopropan-2-yl)-4-methoxybenzenesulfonamide
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
158
structure length
158
Chain Sequence
GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Exploring the subtleties of drug-receptor interactions: the case of matrix metalloproteinases.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Macrophage metalloelastase
total genus 43
structure length 158
sequence length 158
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2008-10-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3f16A00
2A8HA 2SRTA 1R1HA 2JNPA 2J83A 2RJPA 3DSLA 2D1NA 2W14A 1JJ9A 5D2BA 1MNCA 4IUWA 4J4MA 2MZIA 4Q1LA 1IAEA 1ZXCA 2OY4A 2OW9A 3B2ZA 5D3CA 4GR3A 2AIGP 1Q3AA 2OVXA 3LQ0A 3VTGA 1D8FA 3V96B 3LKAA 5D7WA 3KECA 4FXQA 2WO9A 1RM8A 1C8TA 2O3EA 2OXUA 1GXDA 2OW0A 1BKCE 2OY2A 3AYUA 3LIKA 1GO8P 1CIZA 3EHXA 1CQRA 1OM6A 1J7NA 1YP1A 2W13A 1IABA 3USNA 5BOYA 5I0LA 3HDAP 3DPFA 3LMCA 4FVLA 1GE7A 4ZR5A 2I47A 1MMQA 5CZMA 1G9KA 2WOAA 4GWMA 2TCLA 1MMPA 2MLSA 4G9LA 4JA1A 1CK7A 3F19A 1ATLA 1XUDA 1L6JA 2AYKA 2OW1A 1XFUA 1UMSA 5B5OA 1I1IP 1UMTA 1XFZA 4JQGA 2OXWA 4GQLA 2MZEA 2W15A 3HBUP 3LILA 1R1JA 4GUYA 3L0VA 1EUBA 1USNA 1CAQA 1DMTA 1XURA 4IN9A 1BM6A 3BA0A 2E2DA 3EHYA 1B8YA 2CKIA 1JIZA 4XCTA 1O0QA 2DW1A 5H8XA 1AKLA 1UTZA 2ERQA 3TVCA 4XM7A 2MLRA 1BKCA 3LUNA 4G0DA 3DL1A 1GO7P 1Z3JA 3HBVP 1OO9A 3NX7A 1BKCI 5B5PA 1CXVA 2O36A 1GKDA 1ZVXA 1SMPA 1EAKA 3F16A 1IAGA 1JIWP 3LK8A 4GF1A 2QPJA 3KEJA 3EDZA 1A85A 4WK7A 1YCMA 2MZHA 1C3IA 5D1TA 3EDIA 3Q2HA 1BQQM 1IADA 3LQBA 3KMCA 2OW2A 2OXZA 1ZXVA 4FXYP 2W0DA 1FLSA 4DF9A 4H76A 2L0RA 1HV5A 2USNA 3U1RA 4PKSA 1ZP5A 1CGLA 2CLTA 5I3MA 3HYGA 1XFYA 3TSKA 1WNIA 1Y0VA 3ELMA 4DD8A 2EROA 1Y8JA 1G4KA 1C7KA 2DW2A 3KHIA 1JH1A 2D1OA 1YQYA 966CA 1KBCA 1SATA 4PKRA 4H1QA 1ZTQA 3DWBA 1QUAA 4L6TA 1JKYA 2K9CA 3WV1A 3ZUKA 5JMYA 3HDBA 3TT4A 1G05A 2RJQA 1KUGA 4HMAA 1S4BP 4DV8A 4A7BA 1XUCA 2FV5A 3HB2P 1XFVA 3F15A 3GBOA 2JT5A 1QJIA 3CKIA 1PWPA 4A3WA 2N8RA 2XS4A 4PKWA 1QIAA 1CGEA 1GE6A 1I73A 5LABA 5L79A 1JK3A 1OM7A 1QIBA 4QKZA 4WKEA 1JAQA 3AIGA 1D8MA 1PWQA 4AIGA 4AUOA 5D1SA 3EDHA 456CA 3B8ZA 3EWJA 4H82A 1KUFA 2XS3A 3B92A 2X3BA 4L19A 1MMRA 2J0TA 1BQOA 4H30A 1QICA 3F1AA 3TS4A 3WV3A 3KMEA 1K7GA 1UTTA 3K7LA 1OS9A 4PKVA 1YOUA 1H71P 2PJTA 1HY7A 4XM8A 2OI0A 1BIWA 4DPEA 1CGFA 4AYKA 4JPAA 3RTSA 1R1IA 5BPAA 3E8RA 3OHOA 3KWVC 1I76A 5CXAA 4PKQA 3LUMA 3MA2A 1BUVM 1MMBA 2OZRA 1OMJA 3LEAA 3ZXHA 1QJJA 1Y93A 1JANA 3EDGA 1HTDA 3LGPA 3VI1A 1SU3A 1HOVA 3LE9A 1K7QA 3O2XA 2YB9A 2W12A 1GE5A 1KUHA 1B3DA 1RMZA 4ON1A 1PWVA 3LJZA 1SLMA 2YIGA 830CA 1IACA 5I12A 1JAOA 1ND1A 4PKUA 3KEKA 2JT6A 3KRYA 5CUHA 2FV9A 4H3XA 4L63A 3I7GA 1HFSA 4GR0A 3P24A 3O64A 4FU4A 5BOTA 2K2GA 2X7MA 2DW0A 5L7FA 4AXQA 1XFWA 4H2EA 4PKTA 3DPEA 4CTHA 3G5CA 3G42A 3F17A 1D5JA 2X3AA 1IAAA 4WZVA 2HU6A 3AYKA 4WF6A 3I7IA 3LJTA 2WO8A 5I4OA 1K7IA 3Q2GA 4R3VA 2OVZA 1KAPP 2Y6DA 3P1VA 4H49A 4IJOA 4GR8A 4EFSA 2Z2DA 1SLNA 3HY9A 1PWUA 3K7NA 3N2VA 1PWWA 3RTTA 3DNGA 3N2UA 1FM1A 1XFXA 4JIJA 3LIRA 1O0TA 1D7XA 1ASTA 1R55A 2Y6CA 4XBHA 4H84A 5I2ZA 2E3XA 1BZSA 1EB6A 1KUIA 1ROSA 1OM8A 2X3CA 1AF0A 3LJGA 2JSDA 1KUKA 1BUDA 4ILWD 4GWNA 2POJA 1OS2A 4XM6A 1A86A 1G12A 3UVCA 3HY7A 1G49A 2JIHA 1HFCA 3ZVSA 4I03A 2V4BA 3L0TA 4JP4A 4WKIA 3WV2A 5I43A 3SHIA 4HX3A 1ZS0A 5D1UA 2DDYA 3OHLA 1GKCA 1FBLA 4I35A 2DDFA 2KRJA 1BSWA 1R54A 1JAPA 2ERPA 1DTHA 1UEAA 1AYKA 1SRPA 3F18A
chains in the Genus database with same CATH superfamily
2A8HA 2SRTA 1R1HA 2JNPA 2J83A 2RJPA 3DSLA 2D1NA 2W14A 1JJ9A 5D2BA 1MNCA 4IUWA 4J4MA 2MZIA 4Q1LA 1IAEA 1ZXCA 2OY4A 2OW9A 3B2ZA 5D3CA 4GR3A 2AIGP 1Q3AA 2OVXA 3LQ0A 3VTGA 1D8FA 3V96B 3LKAA 5D7WA 3KECA 4FXQA 2WO9A 1RM8A 1C8TA 2O3EA 2OXUA 1GXDA 2OW0A 1BKCE 2OY2A 3AYUA 3LIKA 1GO8P 1CIZA 3EHXA 1CQRA 1OM6A 1J7NA 1YP1A 2W13A 1IABA 3USNA 5BOYA 5I0LA 3HDAP 3DPFA 3LMCA 4FVLA 3DTIA 1GE7A 4ZR5A 2I47A 1MMQA 5CZMA 1G9KA 2WOAA 4GWMA 2TCLA 1MMPA 2MLSA 4G9LA 4JA1A 1CK7A 3F19A 1ATLA 1XUDA 1L6JA 2AYKA 2OW1A 1XFUA 1UMSA 5B5OA 1I1IP 1UMTA 1XFZA 4JQGA 2OXWA 4GQLA 2MZEA 2W15A 3HBUP 3LILA 1R1JA 4GUYA 3L0VA 1EUBA 1USNA 1CAQA 1DMTA 1XURA 4IN9A 1BM6A 3BA0A 2E2DA 3EHYA 1B8YA 2CKIA 1JIZA 4XCTA 1O0QA 2DW1A 5H8XA 1AKLA 1UTZA 2ERQA 3TVCA 4XM7A 2MLRA 1BKCA 3LUNA 4G0DA 3DL1A 1GO7P 1Z3JA 3HBVP 1OO9A 3NX7A 1BKCI 5B5PA 1CXVA 2O36A 1GKDA 1ZVXA 1SMPA 1EAKA 3F16A 1IAGA 1JIWP 3LK8A 4GF1A 2QPJA 3KEJA 3EDZA 1A85A 4WK7A 1YCMA 2MZHA 1C3IA 1OZ9A 5D1TA 3EDIA 3Q2HA 1BQQM 1IADA 3LQBA 3KMCA 2OW2A 2OXZA 1ZXVA 4FXYP 2W0DA 1FLSA 4DF9A 4L7AA 4H76A 2L0RA 1HV5A 2USNA 3U1RA 4PKSA 1ZP5A 1CGLA 2CLTA 5I3MA 3HYGA 1XFYA 3TSKA 1WNIA 1Y0VA 3ELMA 4DD8A 2EROA 1Y8JA 1G4KA 1C7KA 2DW2A 3KHIA 1JH1A 2D1OA 1YQYA 966CA 1KBCA 1SATA 4PKRA 1XM5A 4H1QA 1ZTQA 3DWBA 1QUAA 4L6TA 1JKYA 2K9CA 3WV1A 3ZUKA 5JMYA 3HDBA 3TT4A 1G05A 2RJQA 1KUGA 4HMAA 1S4BP 4DV8A 4A7BA 1XUCA 2FV5A 3HB2P 1XFVA 3F15A 3GBOA 2JT5A 1QJIA 3CKIA 1PWPA 4A3WA 2N8RA 2XS4A 4PKWA 1QIAA 1CGEA 1GE6A 1I73A 5LABA 5L79A 1JK3A 1OM7A 1QIBA 4QKZA 4WKEA 1JAQA 3AIGA 1D8MA 1PWQA 4AIGA 4AUOA 5D1SA 3EDHA 456CA 3B8ZA 3EWJA 4H82A 1KUFA 2XS3A 3B92A 2X3BA 4L19A 1MMRA 2J0TA 1BQOA 4H30A 1QICA 3F1AA 3TS4A 3WV3A 3KMEA 1K7GA 1UTTA 3K7LA 1OS9A 3DTEA 4PKVA 1YOUA 1H71P 2PJTA 1HY7A 4XM8A 2OI0A 1BIWA 4DPEA 1CGFA 4AYKA 4JPAA 3RTSA 1R1IA 5BPAA 3E8RA 3OHOA 3KWVC 1I76A 5CXAA 4PKQA 3LUMA 3MA2A 1BUVM 1MMBA 2OZRA 1OMJA 3LEAA 3ZXHA 1QJJA 1Y93A 1JANA 3EDGA 1HTDA 3LGPA 3VI1A 1SU3A 1HOVA 3LE9A 1K7QA 3O2XA 2YB9A 2W12A 1GE5A 1KUHA 1B3DA 1RMZA 4ON1A 1PWVA 1TVIA 3LJZA 1SLMA 2YIGA 830CA 1IACA 5I12A 1JAOA 1ND1A 4PKUA 3KEKA 2JT6A 3KRYA 5CUHA 2FV9A 4H3XA 4L63A 3I7GA 1HFSA 4GR0A 3P24A 3O64A 4FU4A 5BOTA 2K2GA 2X7MA 2DW0A 5L7FA 4AXQA 1XFWA 4H2EA 4PKTA 3DPEA 4CTHA 3G5CA 3G42A 3F17A 1D5JA 2X3AA 1IAAA 4WZVA 2HU6A 3AYKA 4WF6A 3I7IA 3LJTA 2WO8A 5I4OA 1K7IA 3Q2GA 4R3VA 2OVZA 1KAPP 2Y6DA 3P1VA 4H49A 4IJOA 4GR8A 4EFSA 2Z2DA 1SLNA 3HY9A 1PWUA 3K7NA 3N2VA 1PWWA 3RTTA 3DNGA 3N2UA 1FM1A 1XFXA 4JIJA 3LIRA 1O0TA 1D7XA 1ASTA 1R55A 1XAXA 2Y6CA 4XBHA 4H84A 5I2ZA 2E3XA 1BZSA 1EB6A 1KUIA 1ROSA 1OM8A 2X3CA 1AF0A 2JSDA 3LJGA 1KUKA 1BUDA 4ILWD 4GWNA 2POJA 1OS2A 4XM6A 1A86A 1G12A 3DTKA 3UVCA 3HY7A 1G49A 2JIHA 1HFCA 3ZVSA 4I03A 2V4BA 3L0TA 4JP4A 4WKIA 3WV2A 5I43A 3SHIA 4HX3A 1ZS0A 5D1UA 2DDYA 3OHLA 1GKCA 1FBLA 4I35A 2DDFA 2YUFA 2KRJA 1BSWA 1R54A 1JAPA 2ERPA 1DTHA 1UEAA 1AYKA 1SRPA 3F18A
chains in the Genus database with same CATH topology
2A8HA 2SRTA 1R1HA 2JNPA 2J83A 2RJPA 3DSLA 2D1NA 2W14A 1JJ9A 5D2BA 1MNCA 4IUWA 4J4MA 2MZIA 4Q1LA 1IAEA 1ZXCA 2OY4A 2OW9A 3B2ZA 5D3CA 4GR3A 2AIGP 1Q3AA 2OVXA 3LQ0A 3VTGA 1D8FA 3V96B 3LKAA 5D7WA 3KECA 4FXQA 2WO9A 1RM8A 1C8TA 2O3EA 2OXUA 1GXDA 2OW0A 1BKCE 2OY2A 3AYUA 3LIKA 1GO8P 1CIZA 3EHXA 1CQRA 1OM6A 1J7NA 1YP1A 2W13A 1IABA 3USNA 5BOYA 5I0LA 3HDAP 3DPFA 3LMCA 4FVLA 3DTIA 1GE7A 4ZR5A 2I47A 1MMQA 5CZMA 1G9KA 2WOAA 4GWMA 2TCLA 1MMPA 2MLSA 4G9LA 4JA1A 1CK7A 3F19A 1ATLA 1XUDA 1L6JA 2AYKA 2OW1A 1XFUA 1UMSA 5B5OA 1I1IP 1UMTA 1XFZA 4JQGA 2OXWA 4GQLA 2MZEA 2W15A 3HBUP 3LILA 1R1JA 4GUYA 3L0VA 1EUBA 1USNA 1CAQA 1DMTA 1XURA 4IN9A 1BM6A 3BA0A 2E2DA 3EHYA 1B8YA 2CKIA 1JIZA 4XCTA 1O0QA 2DW1A 5H8XA 1AKLA 1UTZA 2ERQA 3TVCA 4XM7A 2MLRA 1BKCA 3LUNA 4G0DA 3DL1A 1GO7P 1Z3JA 3HBVP 1OO9A 3NX7A 1BKCI 5B5PA 1CXVA 2O36A 1GKDA 1ZVXA 1SMPA 1EAKA 3F16A 1IAGA 1JIWP 3LK8A 4GF1A 2QPJA 3KEJA 3EDZA 1A85A 4WK7A 1YCMA 2MZHA 1C3IA 5D1TA 3EDIA 3Q2HA 1BQQM 1IADA 3LQBA 3KMCA 2OW2A 2OXZA 1ZXVA 4FXYP 2W0DA 1FLSA 4DF9A 4L7AA 4H76A 2L0RA 1HV5A 2USNA 3U1RA 4PKSA 1ZP5A 1CGLA 2CLTA 5I3MA 3HYGA 1XFYA 3TSKA 1WNIA 1Y0VA 3ELMA 4DD8A 2EROA 1Y8JA 1G4KA 1C7KA 2DW2A 3KHIA 1JH1A 2D1OA 1YQYA 966CA 1KBCA 1SATA 4PKRA 4H1QA 1ZTQA 3DWBA 1QUAA 4L6TA 1JKYA 2K9CA 3WV1A 3ZUKA 5JMYA 3HDBA 3TT4A 1G05A 2RJQA 1KUGA 4HMAA 1S4BP 4DV8A 4A7BA 1XUCA 2FV5A 3HB2P 1XFVA 3F15A 3GBOA 2JT5A 1QJIA 3CKIA 1PWPA 4A3WA 2N8RA 2XS4A 4PKWA 1QIAA 1CGEA 1GE6A 1I73A 5LABA 5L79A 1JK3A 1OM7A 1QIBA 4QKZA 4WKEA 1JAQA 3AIGA 1D8MA 1PWQA 4AIGA 4AUOA 5D1SA 3EDHA 456CA 3B8ZA 3EWJA 4H82A 1KUFA 2XS3A 3B92A 2X3BA 4L19A 1MMRA 2J0TA 1BQOA 4H30A 1QICA 3F1AA 3TS4A 3WV3A 3KMEA 1K7GA 1UTTA 3K7LA 1OS9A 3DTEA 4PKVA 1YOUA 1H71P 2PJTA 1HY7A 4XM8A 2OI0A 1BIWA 4DPEA 1CGFA 4AYKA 4JPAA 3RTSA 1R1IA 5BPAA 3E8RA 3OHOA 3KWVC 1I76A 5CXAA 4PKQA 3LUMA 3MA2A 1BUVM 1MMBA 2OZRA 1OMJA 3LEAA 3ZXHA 1QJJA 1Y93A 1JANA 3EDGA 1HTDA 3LGPA 3VI1A 1SU3A 1HOVA 3LE9A 1K7QA 3O2XA 2YB9A 2W12A 1GE5A 1KUHA 1B3DA 1RMZA 4ON1A 1PWVA 3LJZA 1SLMA 2YIGA 830CA 1IACA 5I12A 1JAOA 1ND1A 4PKUA 3KEKA 2JT6A 3KRYA 5CUHA 2FV9A 4H3XA 4L63A 3I7GA 1HFSA 4GR0A 3P24A 3O64A 4FU4A 5BOTA 2K2GA 2X7MA 2DW0A 5L7FA 4AXQA 1XFWA 4H2EA 4PKTA 3DPEA 4CTHA 3G5CA 3G42A 3F17A 1D5JA 2X3AA 1IAAA 4WZVA 2HU6A 3AYKA 4WF6A 3I7IA 3LJTA 2WO8A 5I4OA 1K7IA 3Q2GA 4R3VA 2OVZA 1KAPP 2Y6DA 3P1VA 4H49A 4IJOA 4GR8A 4EFSA 2Z2DA 1SLNA 3HY9A 1PWUA 3K7NA 3N2VA 1PWWA 3RTTA 3DNGA 3N2UA 1FM1A 1XFXA 4JIJA 3LIRA 1O0TA 1D7XA 1ASTA 1R55A 2Y6CA 4XBHA 4H84A 5I2ZA 2E3XA 1BZSA 1EB6A 1KUIA 1ROSA 1OM8A 2X3CA 1AF0A 3LJGA 2JSDA 1KUKA 1BUDA 4ILWD 4GWNA 2POJA 1OS2A 4XM6A 1A86A 1G12A 3DTKA 3UVCA 3HY7A 1G49A 2JIHA 1HFCA 3ZVSA 4I03A 2V4BA 3L0TA 4JP4A 4WKIA 3WV2A 5I43A 3SHIA 4HX3A 1ZS0A 5D1UA 2DDYA 3OHLA 1GKCA 1FBLA 4I35A 2DDFA 2YUFA 2KRJA 1BSWA 1R54A 1JAPA 2ERPA 1DTHA 1UEAA 1AYKA 1SRPA 3F18A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2A8H A;  2SRT A;  1R1H A;  2JNP A;  2J83 A;  2RJP A;  3DSL A;  2D1N A;  2W14 A;  1JJ9 A;  5D2B A;  1MNC A;  4IUW A;  4J4M A;  2MZI A;  4Q1L A;  1IAE A;  1ZXC A;  2OY4 A;  2OW9 A;  3B2Z A;  5D3C A;  4GR3 A;  2AIG P;  1Q3A A;  2OVX A;  3LQ0 A;  3VTG A;  1D8F A;  3V96 B;  3LKA A;  5D7W A;  3KEC A;  4FXQ A;  2WO9 A;  1RM8 A;  1C8T A;  2O3E A;  2OXU A;  1GXD A;  2OW0 A;  1BKC E;  2OY2 A;  3AYU A;  3LIK A;  1GO8 P;  1CIZ A;  3EHX A;  1CQR A;  1OM6 A;  1J7N A;  1YP1 A;  2W13 A;  1IAB A;  3USN A;  5BOY A;  5I0L A;  3HDA P;  3DPF A;  3LMC A;  4FVL A;  1GE7 A;  4ZR5 A;  2I47 A;  1MMQ A;  5CZM A;  1G9K A;  2WOA A;  4GWM A;  2TCL A;  1MMP A;  2MLS A;  4G9L A;  4JA1 A;  1CK7 A;  3F19 A;  1ATL A;  1XUD A;  1L6J A;  2AYK A;  2OW1 A;  1XFU A;  1UMS A;  5B5O A;  1I1I P;  1UMT A;  1XFZ A;  4JQG A;  2OXW A;  4GQL A;  2MZE A;  2W15 A;  3HBU P;  3LIL A;  1R1J A;  4GUY A;  3L0V A;  1EUB A;  1USN A;  1CAQ A;  1DMT A;  1XUR A;  4IN9 A;  1BM6 A;  3BA0 A;  2E2D A;  3EHY A;  1B8Y A;  2CKI A;  1JIZ A;  4XCT A;  1O0Q A;  2DW1 A;  5H8X A;  1AKL A;  1UTZ A;  2ERQ A;  3TVC A;  4XM7 A;  2MLR A;  1BKC A;  3LUN A;  4G0D A;  3DL1 A;  1GO7 P;  1Z3J A;  3HBV P;  1OO9 A;  3NX7 A;  1BKC I;  5B5P A;  1CXV A;  2O36 A;  1GKD A;  1ZVX A;  1SMP A;  1EAK A;  3F16 A;  1IAG A;  1JIW P;  3LK8 A;  4GF1 A;  2QPJ A;  3KEJ A;  3EDZ A;  1A85 A;  4WK7 A;  1YCM A;  2MZH A;  1C3I A;  5D1T A;  3EDI A;  3Q2H A;  1BQQ M;  1IAD A;  3LQB A;  3KMC A;  2OW2 A;  2OXZ A;  1ZXV A;  4FXY P;  2W0D A;  1FLS A;  4DF9 A;  4H76 A;  2L0R A;  1HV5 A;  2USN A;  3U1R A;  4PKS A;  1ZP5 A;  1CGL A;  2CLT A;  5I3M A;  3HYG A;  1XFY A;  3TSK A;  1WNI A;  1Y0V A;  3ELM A;  4DD8 A;  2ERO A;  1Y8J A;  1G4K A;  1C7K A;  2DW2 A;  3KHI A;  1JH1 A;  2D1O A;  1YQY A;  966C A;  1KBC A;  1SAT A;  4PKR A;  4H1Q A;  1ZTQ A;  3DWB A;  1QUA A;  4L6T A;  1JKY A;  2K9C A;  3WV1 A;  3ZUK A;  5JMY A;  3HDB A;  3TT4 A;  1G05 A;  2RJQ A;  1KUG A;  4HMA A;  1S4B P;  4DV8 A;  4A7B A;  1XUC A;  2FV5 A;  3HB2 P;  1XFV A;  3F15 A;  3GBO A;  2JT5 A;  1QJI A;  3CKI A;  1PWP A;  4A3W A;  2N8R A;  2XS4 A;  4PKW A;  1QIA A;  1CGE A;  1GE6 A;  1I73 A;  5LAB A;  5L79 A;  1JK3 A;  1OM7 A;  1QIB A;  4QKZ A;  4WKE A;  1JAQ A;  3AIG A;  1D8M A;  1PWQ A;  4AIG A;  4AUO A;  5D1S A;  3EDH A;  456C A;  3B8Z A;  3EWJ A;  4H82 A;  1KUF A;  2XS3 A;  3B92 A;  2X3B A;  4L19 A;  1MMR A;  2J0T A;  1BQO A;  4H30 A;  1QIC A;  3F1A A;  3TS4 A;  3WV3 A;  3KME A;  1K7G A;  1UTT A;  3K7L A;  1OS9 A;  4PKV A;  1YOU A;  1H71 P;  2PJT A;  1HY7 A;  4XM8 A;  2OI0 A;  1BIW A;  4DPE A;  1CGF A;  4AYK A;  4JPA A;  3RTS A;  1R1I A;  5BPA A;  3E8R A;  3OHO A;  3KWV C;  1I76 A;  5CXA A;  4PKQ A;  3LUM A;  3MA2 A;  1BUV M;  1MMB A;  2OZR A;  1OMJ A;  3LEA A;  3ZXH A;  1QJJ A;  1Y93 A;  1JAN A;  3EDG A;  1HTD A;  3LGP A;  3VI1 A;  1SU3 A;  1HOV A;  3LE9 A;  1K7Q A;  3O2X A;  2YB9 A;  2W12 A;  1GE5 A;  1KUH A;  1B3D A;  1RMZ A;  4ON1 A;  1PWV A;  3LJZ A;  1SLM A;  2YIG A;  830C A;  1IAC A;  5I12 A;  1JAO A;  1ND1 A;  4PKU A;  3KEK A;  2JT6 A;  3KRY A;  5CUH A;  2FV9 A;  4H3X A;  4L63 A;  3I7G A;  1HFS A;  4GR0 A;  3P24 A;  3O64 A;  4FU4 A;  5BOT A;  2K2G A;  2X7M A;  2DW0 A;  5L7F A;  4AXQ A;  1XFW A;  4H2E A;  4PKT A;  3DPE A;  4CTH A;  3G5C A;  3G42 A;  3F17 A;  1D5J A;  2X3A A;  1IAA A;  4WZV A;  2HU6 A;  3AYK A;  4WF6 A;  3I7I A;  3LJT A;  2WO8 A;  5I4O A;  1K7I A;  3Q2G A;  4R3V A;  2OVZ A;  1KAP P;  2Y6D A;  3P1V A;  4H49 A;  4IJO A;  4GR8 A;  4EFS A;  2Z2D A;  1SLN A;  3HY9 A;  1PWU A;  3K7N A;  3N2V A;  1PWW A;  3RTT A;  3DNG A;  3N2U A;  1FM1 A;  1XFX A;  4JIJ A;  3LIR A;  1O0T A;  1D7X A;  1AST A;  1R55 A;  2Y6C A;  4XBH A;  4H84 A;  5I2Z A;  2E3X A;  1BZS A;  1EB6 A;  1KUI A;  1ROS A;  1OM8 A;  2X3C A;  1AF0 A;  3LJG A;  2JSD A;  1KUK A;  1BUD A;  4ILW D;  4GWN A;  2POJ A;  1OS2 A;  4XM6 A;  1A86 A;  1G12 A;  3UVC A;  3HY7 A;  1G49 A;  2JIH A;  1HFC A;  3ZVS A;  4I03 A;  2V4B A;  3L0T A;  4JP4 A;  4WKI A;  3WV2 A;  5I43 A;  3SHI A;  4HX3 A;  1ZS0 A;  5D1U A;  2DDY A;  3OHL A;  1GKC A;  1FBL A;  4I35 A;  2DDF A;  2KRJ A;  1BSW A;  1R54 A;  1JAP A;  2ERP A;  1DTH A;  1UEA A;  1AYK A;  1SRP A;  3F18 A; 
#chains in the Genus database with same CATH topology
 2A8H A;  2SRT A;  1R1H A;  2JNP A;  2J83 A;  2RJP A;  3DSL A;  2D1N A;  2W14 A;  1JJ9 A;  5D2B A;  1MNC A;  4IUW A;  4J4M A;  2MZI A;  4Q1L A;  1IAE A;  1ZXC A;  2OY4 A;  2OW9 A;  3B2Z A;  5D3C A;  4GR3 A;  2AIG P;  1Q3A A;  2OVX A;  3LQ0 A;  3VTG A;  1D8F A;  3V96 B;  3LKA A;  5D7W A;  3KEC A;  4FXQ A;  2WO9 A;  1RM8 A;  1C8T A;  2O3E A;  2OXU A;  1GXD A;  2OW0 A;  1BKC E;  2OY2 A;  3AYU A;  3LIK A;  1GO8 P;  1CIZ A;  3EHX A;  1CQR A;  1OM6 A;  1J7N A;  1YP1 A;  2W13 A;  1IAB A;  3USN A;  5BOY A;  5I0L A;  3HDA P;  3DPF A;  3LMC A;  4FVL A;  3DTI A;  1GE7 A;  4ZR5 A;  2I47 A;  1MMQ A;  5CZM A;  1G9K A;  2WOA A;  4GWM A;  2TCL A;  1MMP A;  2MLS A;  4G9L A;  4JA1 A;  1CK7 A;  3F19 A;  1ATL A;  1XUD A;  1L6J A;  2AYK A;  2OW1 A;  1XFU A;  1UMS A;  5B5O A;  1I1I P;  1UMT A;  1XFZ A;  4JQG A;  2OXW A;  4GQL A;  2MZE A;  2W15 A;  3HBU P;  3LIL A;  1R1J A;  4GUY A;  3L0V A;  1EUB A;  1USN A;  1CAQ A;  1DMT A;  1XUR A;  4IN9 A;  1BM6 A;  3BA0 A;  2E2D A;  3EHY A;  1B8Y A;  2CKI A;  1JIZ A;  4XCT A;  1O0Q A;  2DW1 A;  5H8X A;  1AKL A;  1UTZ A;  2ERQ A;  3TVC A;  4XM7 A;  2MLR A;  1BKC A;  3LUN A;  4G0D A;  3DL1 A;  1GO7 P;  1Z3J A;  3HBV P;  1OO9 A;  3NX7 A;  1BKC I;  5B5P A;  1CXV A;  2O36 A;  1GKD A;  1ZVX A;  1SMP A;  1EAK A;  3F16 A;  1IAG A;  1JIW P;  3LK8 A;  4GF1 A;  2QPJ A;  3KEJ A;  3EDZ A;  1A85 A;  4WK7 A;  1YCM A;  2MZH A;  1C3I A;  1OZ9 A;  5D1T A;  3EDI A;  3Q2H A;  1BQQ M;  1IAD A;  3LQB A;  3KMC A;  2OW2 A;  2OXZ A;  1ZXV A;  4FXY P;  2W0D A;  1FLS A;  4DF9 A;  4L7A A;  4H76 A;  2L0R A;  1HV5 A;  2USN A;  3U1R A;  4PKS A;  1ZP5 A;  1CGL A;  2CLT A;  5I3M A;  3HYG A;  1XFY A;  3TSK A;  1WNI A;  1Y0V A;  3ELM A;  4DD8 A;  2ERO A;  1Y8J A;  1G4K A;  1C7K A;  2DW2 A;  3KHI A;  1JH1 A;  2D1O A;  1YQY A;  966C A;  1KBC A;  1SAT A;  4PKR A;  1XM5 A;  4H1Q A;  1ZTQ A;  3DWB A;  1QUA A;  4L6T A;  1JKY A;  2K9C A;  3WV1 A;  3ZUK A;  5JMY A;  3HDB A;  3TT4 A;  1G05 A;  2RJQ A;  1KUG A;  4HMA A;  1S4B P;  4DV8 A;  4A7B A;  1XUC A;  2FV5 A;  3HB2 P;  1XFV A;  3F15 A;  3GBO A;  2JT5 A;  1QJI A;  3CKI A;  1PWP A;  4A3W A;  2N8R A;  2XS4 A;  4PKW A;  1QIA A;  1CGE A;  1GE6 A;  1I73 A;  5LAB A;  5L79 A;  1JK3 A;  1OM7 A;  1QIB A;  4QKZ A;  4WKE A;  1JAQ A;  3AIG A;  1D8M A;  1PWQ A;  4AIG A;  4AUO A;  5D1S A;  3EDH A;  456C A;  3B8Z A;  3EWJ A;  4H82 A;  1KUF A;  2XS3 A;  3B92 A;  2X3B A;  4L19 A;  1MMR A;  2J0T A;  1BQO A;  4H30 A;  1QIC A;  3F1A A;  3TS4 A;  3WV3 A;  3KME A;  1K7G A;  1UTT A;  3K7L A;  1OS9 A;  3DTE A;  4PKV A;  1YOU A;  1H71 P;  2PJT A;  1HY7 A;  4XM8 A;  2OI0 A;  1BIW A;  4DPE A;  1CGF A;  4AYK A;  4JPA A;  3RTS A;  1R1I A;  5BPA A;  3E8R A;  3OHO A;  3KWV C;  1I76 A;  5CXA A;  4PKQ A;  3LUM A;  3MA2 A;  1BUV M;  1MMB A;  2OZR A;  1OMJ A;  3LEA A;  3ZXH A;  1QJJ A;  1Y93 A;  1JAN A;  3EDG A;  1HTD A;  3LGP A;  3VI1 A;  1SU3 A;  1HOV A;  3LE9 A;  1K7Q A;  3O2X A;  2YB9 A;  2W12 A;  1GE5 A;  1KUH A;  1B3D A;  1RMZ A;  4ON1 A;  1PWV A;  1TVI A;  3LJZ A;  1SLM A;  2YIG A;  830C A;  1IAC A;  5I12 A;  1JAO A;  1ND1 A;  4PKU A;  3KEK A;  2JT6 A;  3KRY A;  5CUH A;  2FV9 A;  4H3X A;  4L63 A;  3I7G A;  1HFS A;  4GR0 A;  3P24 A;  3O64 A;  4FU4 A;  5BOT A;  2K2G A;  2X7M A;  2DW0 A;  5L7F A;  4AXQ A;  1XFW A;  4H2E A;  4PKT A;  3DPE A;  4CTH A;  3G5C A;  3G42 A;  3F17 A;  1D5J A;  2X3A A;  1IAA A;  4WZV A;  2HU6 A;  3AYK A;  4WF6 A;  3I7I A;  3LJT A;  2WO8 A;  5I4O A;  1K7I A;  3Q2G A;  4R3V A;  2OVZ A;  1KAP P;  2Y6D A;  3P1V A;  4H49 A;  4IJO A;  4GR8 A;  4EFS A;  2Z2D A;  1SLN A;  3HY9 A;  1PWU A;  3K7N A;  3N2V A;  1PWW A;  3RTT A;  3DNG A;  3N2U A;  1FM1 A;  1XFX A;  4JIJ A;  3LIR A;  1O0T A;  1D7X A;  1AST A;  1R55 A;  1XAX A;  2Y6C A;  4XBH A;  4H84 A;  5I2Z A;  2E3X A;  1BZS A;  1EB6 A;  1KUI A;  1ROS A;  1OM8 A;  2X3C A;  1AF0 A;  2JSD A;  3LJG A;  1KUK A;  1BUD A;  4ILW D;  4GWN A;  2POJ A;  1OS2 A;  4XM6 A;  1A86 A;  1G12 A;  3DTK A;  3UVC A;  3HY7 A;  1G49 A;  2JIH A;  1HFC A;  3ZVS A;  4I03 A;  2V4B A;  3L0T A;  4JP4 A;  4WKI A;  3WV2 A;  5I43 A;  3SHI A;  4HX3 A;  1ZS0 A;  5D1U A;  2DDY A;  3OHL A;  1GKC A;  1FBL A;  4I35 A;  2DDF A;  2YUF A;  2KRJ A;  1BSW A;  1R54 A;  1JAP A;  2ERP A;  1DTH A;  1UEA A;  1AYK A;  1SRP A;  3F18 A; 
#chains in the Genus database with same CATH homology
 2A8H A;  2SRT A;  1R1H A;  2JNP A;  2J83 A;  2RJP A;  3DSL A;  2D1N A;  2W14 A;  1JJ9 A;  5D2B A;  1MNC A;  4IUW A;  4J4M A;  2MZI A;  4Q1L A;  1IAE A;  1ZXC A;  2OY4 A;  2OW9 A;  3B2Z A;  5D3C A;  4GR3 A;  2AIG P;  1Q3A A;  2OVX A;  3LQ0 A;  3VTG A;  1D8F A;  3V96 B;  3LKA A;  5D7W A;  3KEC A;  4FXQ A;  2WO9 A;  1RM8 A;  1C8T A;  2O3E A;  2OXU A;  1GXD A;  2OW0 A;  1BKC E;  2OY2 A;  3AYU A;  3LIK A;  1GO8 P;  1CIZ A;  3EHX A;  1CQR A;  1OM6 A;  1J7N A;  1YP1 A;  2W13 A;  1IAB A;  3USN A;  5BOY A;  5I0L A;  3HDA P;  3DPF A;  3LMC A;  4FVL A;  3DTI A;  1GE7 A;  4ZR5 A;  2I47 A;  1MMQ A;  5CZM A;  1G9K A;  2WOA A;  4GWM A;  2TCL A;  1MMP A;  2MLS A;  4G9L A;  4JA1 A;  1CK7 A;  3F19 A;  1ATL A;  1XUD A;  1L6J A;  2AYK A;  2OW1 A;  1XFU A;  1UMS A;  5B5O A;  1I1I P;  1UMT A;  1XFZ A;  4JQG A;  2OXW A;  4GQL A;  2MZE A;  2W15 A;  3HBU P;  3LIL A;  1R1J A;  4GUY A;  3L0V A;  1EUB A;  1USN A;  1CAQ A;  1DMT A;  1XUR A;  4IN9 A;  1BM6 A;  3BA0 A;  2E2D A;  3EHY A;  1B8Y A;  2CKI A;  1JIZ A;  4XCT A;  1O0Q A;  2DW1 A;  5H8X A;  1AKL A;  1UTZ A;  2ERQ A;  3TVC A;  4XM7 A;  2MLR A;  1BKC A;  3LUN A;  4G0D A;  3DL1 A;  1GO7 P;  1Z3J A;  3HBV P;  1OO9 A;  3NX7 A;  1BKC I;  5B5P A;  1CXV A;  2O36 A;  1GKD A;  1ZVX A;  1SMP A;  1EAK A;  3F16 A;  1IAG A;  1JIW P;  3LK8 A;  4GF1 A;  2QPJ A;  3KEJ A;  3EDZ A;  1A85 A;  4WK7 A;  1YCM A;  2MZH A;  1C3I A;  5D1T A;  3EDI A;  3Q2H A;  1BQQ M;  1IAD A;  3LQB A;  3KMC A;  2OW2 A;  2OXZ A;  1ZXV A;  4FXY P;  2W0D A;  1FLS A;  4DF9 A;  4L7A A;  4H76 A;  2L0R A;  1HV5 A;  2USN A;  3U1R A;  4PKS A;  1ZP5 A;  1CGL A;  2CLT A;  5I3M A;  3HYG A;  1XFY A;  3TSK A;  1WNI A;  1Y0V A;  3ELM A;  4DD8 A;  2ERO A;  1Y8J A;  1G4K A;  1C7K A;  2DW2 A;  3KHI A;  1JH1 A;  2D1O A;  1YQY A;  966C A;  1KBC A;  1SAT A;  4PKR A;  4H1Q A;  1ZTQ A;  3DWB A;  1QUA A;  4L6T A;  1JKY A;  2K9C A;  3WV1 A;  3ZUK A;  5JMY A;  3HDB A;  3TT4 A;  1G05 A;  2RJQ A;  1KUG A;  4HMA A;  1S4B P;  4DV8 A;  4A7B A;  1XUC A;  2FV5 A;  3HB2 P;  1XFV A;  3F15 A;  3GBO A;  2JT5 A;  1QJI A;  3CKI A;  1PWP A;  4A3W A;  2N8R A;  2XS4 A;  4PKW A;  1QIA A;  1CGE A;  1GE6 A;  1I73 A;  5LAB A;  5L79 A;  1JK3 A;  1OM7 A;  1QIB A;  4QKZ A;  4WKE A;  1JAQ A;  3AIG A;  1D8M A;  1PWQ A;  4AIG A;  4AUO A;  5D1S A;  3EDH A;  456C A;  3B8Z A;  3EWJ A;  4H82 A;  1KUF A;  2XS3 A;  3B92 A;  2X3B A;  4L19 A;  1MMR A;  2J0T A;  1BQO A;  4H30 A;  1QIC A;  3F1A A;  3TS4 A;  3WV3 A;  3KME A;  1K7G A;  1UTT A;  3K7L A;  1OS9 A;  3DTE A;  4PKV A;  1YOU A;  1H71 P;  2PJT A;  1HY7 A;  4XM8 A;  2OI0 A;  1BIW A;  4DPE A;  1CGF A;  4AYK A;  4JPA A;  3RTS A;  1R1I A;  5BPA A;  3E8R A;  3OHO A;  3KWV C;  1I76 A;  5CXA A;  4PKQ A;  3LUM A;  3MA2 A;  1BUV M;  1MMB A;  2OZR A;  1OMJ A;  3LEA A;  3ZXH A;  1QJJ A;  1Y93 A;  1JAN A;  3EDG A;  1HTD A;  3LGP A;  3VI1 A;  1SU3 A;  1HOV A;  3LE9 A;  1K7Q A;  3O2X A;  2YB9 A;  2W12 A;  1GE5 A;  1KUH A;  1B3D A;  1RMZ A;  4ON1 A;  1PWV A;  3LJZ A;  1SLM A;  2YIG A;  830C A;  1IAC A;  5I12 A;  1JAO A;  1ND1 A;  4PKU A;  3KEK A;  2JT6 A;  3KRY A;  5CUH A;  2FV9 A;  4H3X A;  4L63 A;  3I7G A;  1HFS A;  4GR0 A;  3P24 A;  3O64 A;  4FU4 A;  5BOT A;  2K2G A;  2X7M A;  2DW0 A;  5L7F A;  4AXQ A;  1XFW A;  4H2E A;  4PKT A;  3DPE A;  4CTH A;  3G5C A;  3G42 A;  3F17 A;  1D5J A;  2X3A A;  1IAA A;  4WZV A;  2HU6 A;  3AYK A;  4WF6 A;  3I7I A;  3LJT A;  2WO8 A;  5I4O A;  1K7I A;  3Q2G A;  4R3V A;  2OVZ A;  1KAP P;  2Y6D A;  3P1V A;  4H49 A;  4IJO A;  4GR8 A;  4EFS A;  2Z2D A;  1SLN A;  3HY9 A;  1PWU A;  3K7N A;  3N2V A;  1PWW A;  3RTT A;  3DNG A;  3N2U A;  1FM1 A;  1XFX A;  4JIJ A;  3LIR A;  1O0T A;  1D7X A;  1AST A;  1R55 A;  2Y6C A;  4XBH A;  4H84 A;  5I2Z A;  2E3X A;  1BZS A;  1EB6 A;  1KUI A;  1ROS A;  1OM8 A;  2X3C A;  1AF0 A;  3LJG A;  2JSD A;  1KUK A;  1BUD A;  4ILW D;  4GWN A;  2POJ A;  1OS2 A;  4XM6 A;  1A86 A;  1G12 A;  3DTK A;  3UVC A;  3HY7 A;  1G49 A;  2JIH A;  1HFC A;  3ZVS A;  4I03 A;  2V4B A;  3L0T A;  4JP4 A;  4WKI A;  3WV2 A;  5I43 A;  3SHI A;  4HX3 A;  1ZS0 A;  5D1U A;  2DDY A;  3OHL A;  1GKC A;  1FBL A;  4I35 A;  2DDF A;  2YUF A;  2KRJ A;  1BSW A;  1R54 A;  1JAP A;  2ERP A;  1DTH A;  1UEA A;  1AYK A;  1SRP A;  3F18 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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