3F18A

Crystal structure of the catalytic domain of human mmp12 complexed with the inhibitor 4-fluoro-n-(2-hydroxyethyl)-n-(2-nitroso-2-oxoethyl)benzenesulfonamide
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
158
structure length
158
Chain Sequence
GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Exploring the subtleties of drug-receptor interactions: the case of matrix metalloproteinases.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Macrophage metalloelastase
total genus 43
structure length 158
sequence length 158
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2008-10-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3f18A00
3U1RA 4JA1A 1JIWP 1AF0A 3LIRA 3HDAP 4DV8A 1A86A 2Y6DA 1C7KA 2O36A 4H3XA 2WOAA 1D8FA 1JJ9A 1GKDA 2PJTA 2OW9A 2JT5A 3B92A 5I2ZA 2MZEA 3OHLA 2USNA 2W14A 3AIGA 2MLRA 2OW2A 5D3CA 3HBUP 1Y93A 1IAAA 1WNIA 2RJPA 4H2EA 3SHIA 2POJA 3HB2P 966CA 2HU6A 1D5JA 4I03A 1MMQA 1BKCE 1OO9A 5L79A 2Z2DA 3WV1A 3O64A 2CKIA 5D1TA 1EB6A 3BA0A 4AUOA 1ZP5A 1JIZA 3ZVSA 1Z3JA 3I7GA 1OS2A 2J0TA 1QJJA 5BOTA 3I7IA 3AYKA 4EFSA 1XFXA 1RM8A 1XFYA 4H30A 3EHXA 3ZXHA 3F19A 1CAQA 2MLSA 2XS4A 3HYGA 4JQGA 3EDGA 1CK7A 3Q2GA 1I1IP 3G5CA 4CTHA 4FU4A 4IUWA 4DD8A 1R54A 1BKCI 2OY4A 1G12A 1YOUA 5H8XA 1OM8A 3EHYA 2ERQA 1BZSA 3DPEA 4H82A 4HX3A 1OM6A 3LKAA 1BUDA 4FVLA 1CXVA 1HY7A 1SLNA 1SMPA 3MA2A 1FBLA 4AYKA 4DF9A 1HFSA 1C3IA 2OY2A 3UVCA 1UEAA 3KMEA 1PWQA 2DW1A 1UMSA 1BKCA 1KUGA 1Q3AA 1PWUA 1D8MA 3DL1A 2OXWA 3EDZA 2AIGP 4GQLA 1XUDA 4PKWA 1BM6A 2OZRA 1EAKA 2MZHA 4WF6A 4GWNA 3RTSA 4XM8A 1JK3A 3KEJA 3KECA 1ZS0A 4QKZA 3WV3A 4I35A 3HBVP 3LQ0A 2JSDA 3DWBA 3LMCA 1HTDA 2E2DA 1KUIA 2OW0A 4PKQA 3N2UA 1D7XA 1K7QA 1PWWA 1XFUA 3K7NA 4GWMA 5I0LA 4ZR5A 4PKUA 2OXUA 3LK8A 1BUVM 1GXDA 1ZTQA 2RJQA 2QPJA 4ILWD 3LE9A 2X3CA 3Q2HA 830CA 1J7NA 3LJTA 1KUHA 3P24A 1JAOA 2Y6CA 4G9LA 1GO8P 4H1QA 4XM7A 5CXAA 3WV2A 1HOVA 1A85A 1QJIA 5I3MA 2K9CA 3HDBA 2W15A 3LUMA 3DSLA 1O0QA 1Y0VA 1XFWA 2L0RA 1YP1A 1I76A 3VTGA 1BQOA 1C8TA 3KRYA 2X7MA 1GE6A 1CGLA 1JANA 1G49A 3KWVC 4H84A 4XCTA 1JKYA 3LEAA 1UMTA 1MMBA 3TVCA 1GKCA 1SLMA 1XFVA 4GR0A 1S4BP 2D1NA 2WO9A 3USNA 2N8RA 5L7FA 3LQBA 3ZUKA 3CKIA 1IABA 3EWJA 1AKLA 5D2BA 1R1HA 4L19A 4DPEA 4IN9A 4GR3A 2WO8A 1UTTA 1ZXCA 4JP4A 1USNA 1KAPP 2YIGA 2W0DA 4GR8A 4PKTA 4JPAA 2OVZA 1ASTA 3DNGA 1G05A 4HMAA 1HV5A 4JIJA 5I12A 2J83A 1KUFA 4FXYP 1XUCA 1ND1A 3RTTA 2DDFA 1EUBA 1IACA 3GBOA 1K7GA 4GUYA 2D1OA 2A8HA 3E8RA 2OW1A 2MZIA 4PKVA 4WKEA 1Y8JA 1XFZA 3HY7A 1G9KA 1UTZA 2SRTA 3F17A 3B2ZA 3V96B 3OHOA 1ROSA 4XBHA 1ZVXA 1B3DA 1L6JA 1I73A 3EDHA 4R3VA 5D7WA 5JMYA 4PKRA 4WK7A 1PWPA 3LJGA 4L63A 3EDIA 1GO7P 1QIAA 3F16A 1BQQM 3F15A 1BSWA 3LUNA 2I47A 1FLSA 1KBCA 3NX7A 4XM6A 1QUAA 2JIHA 5CZMA 1IAGA 2W12A 1O0TA 1OS9A 3LGPA 2XS3A 3DPFA 2AYKA 4A7BA 456CA 3LILA 4H49A 3KMCA 1B8YA 1CGFA 2O3EA 1AYKA 4IJOA 3LIKA 4WKIA 3AYUA 3TSKA 1QIBA 1FM1A 2JNPA 1GE7A 2DW0A 1RMZA 4L6TA 2FV5A 2E3XA 5D1SA 1R1IA 4H76A 3ELMA 2OXZA 3B8ZA 4PKSA 3O2XA 2X3BA 2ERPA 1BIWA 5LABA 1K7IA 1SRPA 5B5PA 5BPAA 2DDYA 5B5OA 3LJZA 1ZXVA 4J4MA 1G4KA 2EROA 1SATA 1DTHA 1ATLA 3G42A 2FV9A 3L0VA 3L0TA 3K7LA 3TS4A 1SU3A 1IAEA 1R1JA 4A3WA 1QICA 1CQRA 5I4OA 1YQYA 1CGEA 1MMRA 2V4BA 2OVXA 4ON1A 1MNCA 1HFCA 1CIZA 2W13A 1MMPA 3TT4A 3KEKA 1IADA 2X3AA 2YB9A 3HY9A 1DMTA 3KHIA 1JH1A 2TCLA 2OI0A 3P1VA 3N2VA 4G0DA 1KUKA 1OMJA 2JT6A 1GE5A 1XURA 1PWVA 2KRJA 5D1UA 2CLTA 4WZVA 1JAPA 1YCMA 5I43A 3F18A 4GF1A 1OM7A 3F1AA 4FXQA 4Q1LA 1R55A 5CUHA 2DW2A 4AXQA 5BOYA 1H71P 3VI1A 2K2GA 4AIGA 1JAQA
chains in the Genus database with same CATH superfamily
3U1RA 4JA1A 1JIWP 1AF0A 3LIRA 3HDAP 4DV8A 1A86A 2Y6DA 1C7KA 2O36A 4H3XA 2WOAA 1D8FA 1JJ9A 1GKDA 2PJTA 2OW9A 2JT5A 3B92A 5I2ZA 2MZEA 3OHLA 2USNA 2W14A 3AIGA 2MLRA 2OW2A 5D3CA 3HBUP 1Y93A 1IAAA 1WNIA 2RJPA 4H2EA 3SHIA 2POJA 3HB2P 966CA 2HU6A 1D5JA 4I03A 1MMQA 1BKCE 1OO9A 5L79A 2Z2DA 3WV1A 3O64A 2CKIA 5D1TA 1EB6A 2YUFA 3BA0A 4AUOA 1ZP5A 1JIZA 3ZVSA 1Z3JA 3I7GA 1OS2A 2J0TA 1QJJA 5BOTA 3I7IA 3AYKA 4EFSA 1XFXA 1RM8A 1XFYA 4H30A 3EHXA 3ZXHA 3F19A 1CAQA 2MLSA 2XS4A 3HYGA 4JQGA 3EDGA 1CK7A 3Q2GA 1I1IP 3G5CA 4CTHA 4FU4A 4IUWA 4DD8A 1R54A 1BKCI 2OY4A 1G12A 1YOUA 5H8XA 1OM8A 3EHYA 2ERQA 1BZSA 3DPEA 4H82A 4HX3A 1OM6A 3LKAA 1OZ9A 1BUDA 4FVLA 1CXVA 1HY7A 1SLNA 1SMPA 3MA2A 1FBLA 4AYKA 4DF9A 1HFSA 1C3IA 2OY2A 3UVCA 1UEAA 3KMEA 1PWQA 2DW1A 1UMSA 1BKCA 1KUGA 1Q3AA 1PWUA 1D8MA 3DL1A 3DTIA 2OXWA 3EDZA 2AIGP 4GQLA 1XUDA 4PKWA 1BM6A 2OZRA 1EAKA 2MZHA 4WF6A 4GWNA 3RTSA 4XM8A 1JK3A 3KEJA 3KECA 1ZS0A 4QKZA 3WV3A 4I35A 3HBVP 3LQ0A 2JSDA 3DWBA 3LMCA 1HTDA 2E2DA 1KUIA 2OW0A 4PKQA 3N2UA 1D7XA 1K7QA 1PWWA 1XFUA 3K7NA 4GWMA 5I0LA 4ZR5A 3DTEA 4PKUA 2OXUA 3LK8A 1BUVM 1GXDA 1ZTQA 2RJQA 2QPJA 4ILWD 3LE9A 2X3CA 3Q2HA 830CA 1J7NA 3LJTA 1KUHA 3P24A 1JAOA 2Y6CA 4G9LA 1GO8P 4H1QA 4XM7A 5CXAA 3WV2A 1HOVA 1A85A 1QJIA 5I3MA 2K9CA 3HDBA 2W15A 3LUMA 3DSLA 1O0QA 1Y0VA 1XFWA 2L0RA 1YP1A 1I76A 3VTGA 1BQOA 1C8TA 3KRYA 2X7MA 1GE6A 1CGLA 1JANA 1G49A 3KWVC 4H84A 4XCTA 1JKYA 3LEAA 1UMTA 1MMBA 3TVCA 1GKCA 1SLMA 4L7AA 1XFVA 4GR0A 1S4BP 2D1NA 2WO9A 3USNA 2N8RA 5L7FA 3LQBA 3ZUKA 3CKIA 1IABA 3EWJA 1AKLA 5D2BA 1R1HA 4L19A 4DPEA 4IN9A 4GR3A 2WO8A 1UTTA 1ZXCA 4JP4A 1USNA 1KAPP 2YIGA 2W0DA 4GR8A 4PKTA 4JPAA 2OVZA 1ASTA 3DNGA 1G05A 4HMAA 1HV5A 4JIJA 5I12A 2J83A 1KUFA 1XAXA 4FXYP 1XUCA 1ND1A 3RTTA 2DDFA 1EUBA 1IACA 3GBOA 1K7GA 4GUYA 2D1OA 2A8HA 3E8RA 2OW1A 2MZIA 4PKVA 4WKEA 1Y8JA 1XFZA 3HY7A 1G9KA 1UTZA 2SRTA 3F17A 3B2ZA 3V96B 3OHOA 1ROSA 4XBHA 1ZVXA 1B3DA 1L6JA 1I73A 3EDHA 4R3VA 5D7WA 5JMYA 4PKRA 4WK7A 1PWPA 3LJGA 4L63A 3EDIA 1GO7P 1QIAA 3F16A 1BQQM 3F15A 1BSWA 3LUNA 2I47A 1FLSA 1KBCA 3NX7A 4XM6A 1QUAA 2JIHA 5CZMA 1IAGA 2W12A 1O0TA 1OS9A 3LGPA 2XS3A 1XM5A 3DPFA 2AYKA 4A7BA 456CA 3LILA 4H49A 3KMCA 1B8YA 1CGFA 2O3EA 1AYKA 4IJOA 3LIKA 4WKIA 3AYUA 3TSKA 1QIBA 1FM1A 2JNPA 1GE7A 2DW0A 1RMZA 4L6TA 2FV5A 2E3XA 5D1SA 1R1IA 4H76A 3ELMA 2OXZA 3B8ZA 4PKSA 3O2XA 2X3BA 2ERPA 1BIWA 5LABA 1K7IA 1SRPA 5B5PA 5BPAA 2DDYA 5B5OA 3LJZA 1ZXVA 4J4MA 1G4KA 2EROA 1SATA 1DTHA 1ATLA 3G42A 2FV9A 3L0VA 3L0TA 3K7LA 3TS4A 1SU3A 1IAEA 1R1JA 4A3WA 1QICA 1CQRA 5I4OA 1YQYA 1CGEA 1MMRA 2V4BA 2OVXA 4ON1A 1MNCA 1TVIA 1HFCA 1CIZA 2W13A 1MMPA 3TT4A 3KEKA 1IADA 3DTKA 2X3AA 2YB9A 3HY9A 1DMTA 3KHIA 1JH1A 2TCLA 2OI0A 3P1VA 3N2VA 4G0DA 1KUKA 1OMJA 2JT6A 1GE5A 1XURA 1PWVA 2KRJA 5D1UA 2CLTA 4WZVA 1JAPA 1YCMA 5I43A 3F18A 4GF1A 1OM7A 3F1AA 4FXQA 4Q1LA 1R55A 5CUHA 2DW2A 4AXQA 5BOYA 1H71P 3VI1A 2K2GA 4AIGA 1JAQA
chains in the Genus database with same CATH topology
3U1RA 4JA1A 1JIWP 1AF0A 3LIRA 3HDAP 4DV8A 1A86A 2Y6DA 1C7KA 2O36A 4H3XA 2WOAA 1D8FA 1JJ9A 1GKDA 2PJTA 2OW9A 2JT5A 3B92A 5I2ZA 2MZEA 3OHLA 2USNA 2W14A 3AIGA 2MLRA 2OW2A 5D3CA 3HBUP 1Y93A 1IAAA 1WNIA 2RJPA 4H2EA 3SHIA 2POJA 3HB2P 966CA 2HU6A 1D5JA 4I03A 1MMQA 1BKCE 1OO9A 5L79A 2Z2DA 3WV1A 3O64A 2CKIA 5D1TA 1EB6A 2YUFA 3BA0A 4AUOA 1ZP5A 1JIZA 3ZVSA 1Z3JA 3I7GA 1OS2A 2J0TA 1QJJA 5BOTA 3I7IA 3AYKA 4EFSA 1XFXA 1RM8A 1XFYA 4H30A 3EHXA 3ZXHA 3F19A 1CAQA 2MLSA 2XS4A 3HYGA 4JQGA 3EDGA 1CK7A 3Q2GA 1I1IP 3G5CA 4CTHA 4FU4A 4IUWA 4DD8A 1R54A 1BKCI 2OY4A 1G12A 1YOUA 5H8XA 1OM8A 3EHYA 2ERQA 1BZSA 3DPEA 4H82A 4HX3A 1OM6A 3LKAA 1BUDA 4FVLA 1CXVA 1HY7A 1SLNA 1SMPA 3MA2A 1FBLA 4AYKA 4DF9A 1HFSA 1C3IA 2OY2A 3UVCA 1UEAA 3KMEA 1PWQA 2DW1A 1UMSA 1BKCA 1KUGA 1Q3AA 1PWUA 1D8MA 3DL1A 3DTIA 2OXWA 3EDZA 2AIGP 4GQLA 1XUDA 4PKWA 1BM6A 2OZRA 1EAKA 2MZHA 4WF6A 4GWNA 3RTSA 4XM8A 1JK3A 3KEJA 3KECA 1ZS0A 4QKZA 3WV3A 4I35A 3HBVP 3LQ0A 2JSDA 3DWBA 3LMCA 1HTDA 2E2DA 1KUIA 2OW0A 4PKQA 3N2UA 1D7XA 1K7QA 1PWWA 1XFUA 3K7NA 4GWMA 5I0LA 4ZR5A 3DTEA 4PKUA 2OXUA 3LK8A 1BUVM 1GXDA 1ZTQA 2RJQA 2QPJA 4ILWD 3LE9A 2X3CA 3Q2HA 830CA 1J7NA 3LJTA 1KUHA 3P24A 1JAOA 2Y6CA 4G9LA 1GO8P 4H1QA 4XM7A 5CXAA 3WV2A 1HOVA 1A85A 1QJIA 5I3MA 2K9CA 3HDBA 2W15A 3LUMA 3DSLA 1O0QA 1Y0VA 1XFWA 2L0RA 1YP1A 1I76A 3VTGA 1BQOA 1C8TA 3KRYA 2X7MA 1GE6A 1CGLA 1JANA 1G49A 3KWVC 4H84A 4XCTA 1JKYA 3LEAA 1UMTA 1MMBA 3TVCA 1GKCA 1SLMA 4L7AA 1XFVA 4GR0A 1S4BP 2D1NA 2WO9A 3USNA 2N8RA 5L7FA 3LQBA 3ZUKA 3CKIA 1IABA 3EWJA 1AKLA 5D2BA 1R1HA 4L19A 4DPEA 4IN9A 4GR3A 2WO8A 1UTTA 1ZXCA 4JP4A 1USNA 1KAPP 2YIGA 2W0DA 4GR8A 4PKTA 4JPAA 2OVZA 1ASTA 3DNGA 1G05A 4HMAA 1HV5A 4JIJA 5I12A 2J83A 1KUFA 4FXYP 1XUCA 1ND1A 3RTTA 2DDFA 1EUBA 1IACA 3GBOA 1K7GA 4GUYA 2D1OA 2A8HA 3E8RA 2OW1A 2MZIA 4PKVA 4WKEA 1Y8JA 1XFZA 3HY7A 1G9KA 1UTZA 2SRTA 3F17A 3B2ZA 3V96B 3OHOA 1ROSA 4XBHA 1ZVXA 1B3DA 1L6JA 1I73A 3EDHA 4R3VA 5D7WA 5JMYA 4PKRA 4WK7A 1PWPA 3LJGA 4L63A 3EDIA 1GO7P 1QIAA 3F16A 1BQQM 3F15A 1BSWA 3LUNA 2I47A 1FLSA 1KBCA 3NX7A 4XM6A 1QUAA 2JIHA 5CZMA 1IAGA 2W12A 1O0TA 1OS9A 3LGPA 2XS3A 3DPFA 2AYKA 4A7BA 456CA 3LILA 4H49A 3KMCA 1B8YA 1CGFA 2O3EA 1AYKA 4IJOA 3LIKA 4WKIA 3AYUA 3TSKA 1QIBA 1FM1A 2JNPA 1GE7A 2DW0A 1RMZA 4L6TA 2FV5A 2E3XA 5D1SA 1R1IA 4H76A 3ELMA 2OXZA 3B8ZA 4PKSA 3O2XA 2X3BA 2ERPA 1BIWA 5LABA 1K7IA 1SRPA 5B5PA 5BPAA 2DDYA 5B5OA 3LJZA 1ZXVA 4J4MA 1G4KA 2EROA 1SATA 1DTHA 1ATLA 3G42A 2FV9A 3L0VA 3L0TA 3K7LA 3TS4A 1SU3A 1IAEA 1R1JA 4A3WA 1QICA 1CQRA 5I4OA 1YQYA 1CGEA 1MMRA 2V4BA 2OVXA 4ON1A 1MNCA 1HFCA 1CIZA 2W13A 1MMPA 3TT4A 3KEKA 1IADA 3DTKA 2X3AA 2YB9A 3HY9A 1DMTA 3KHIA 1JH1A 2TCLA 2OI0A 3P1VA 3N2VA 4G0DA 1KUKA 1OMJA 2JT6A 1GE5A 1XURA 1PWVA 2KRJA 5D1UA 2CLTA 4WZVA 1JAPA 1YCMA 5I43A 3F18A 4GF1A 1OM7A 3F1AA 4FXQA 4Q1LA 1R55A 5CUHA 2DW2A 4AXQA 5BOYA 1H71P 3VI1A 2K2GA 4AIGA 1JAQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3U1R A;  4JA1 A;  1JIW P;  1AF0 A;  3LIR A;  3HDA P;  4DV8 A;  1A86 A;  2Y6D A;  1C7K A;  2O36 A;  4H3X A;  2WOA A;  1D8F A;  1JJ9 A;  1GKD A;  2PJT A;  2OW9 A;  2JT5 A;  3B92 A;  5I2Z A;  2MZE A;  3OHL A;  2USN A;  2W14 A;  3AIG A;  2MLR A;  2OW2 A;  5D3C A;  3HBU P;  1Y93 A;  1IAA A;  1WNI A;  2RJP A;  4H2E A;  3SHI A;  2POJ A;  3HB2 P;  966C A;  2HU6 A;  1D5J A;  4I03 A;  1MMQ A;  1BKC E;  1OO9 A;  5L79 A;  2Z2D A;  3WV1 A;  3O64 A;  2CKI A;  5D1T A;  1EB6 A;  3BA0 A;  4AUO A;  1ZP5 A;  1JIZ A;  3ZVS A;  1Z3J A;  3I7G A;  1OS2 A;  2J0T A;  1QJJ A;  5BOT A;  3I7I A;  3AYK A;  4EFS A;  1XFX A;  1RM8 A;  1XFY A;  4H30 A;  3EHX A;  3ZXH A;  3F19 A;  1CAQ A;  2MLS A;  2XS4 A;  3HYG A;  4JQG A;  3EDG A;  1CK7 A;  3Q2G A;  1I1I P;  3G5C A;  4CTH A;  4FU4 A;  4IUW A;  4DD8 A;  1R54 A;  1BKC I;  2OY4 A;  1G12 A;  1YOU A;  5H8X A;  1OM8 A;  3EHY A;  2ERQ A;  1BZS A;  3DPE A;  4H82 A;  4HX3 A;  1OM6 A;  3LKA A;  1BUD A;  4FVL A;  1CXV A;  1HY7 A;  1SLN A;  1SMP A;  3MA2 A;  1FBL A;  4AYK A;  4DF9 A;  1HFS A;  1C3I A;  2OY2 A;  3UVC A;  1UEA A;  3KME A;  1PWQ A;  2DW1 A;  1UMS A;  1BKC A;  1KUG A;  1Q3A A;  1PWU A;  1D8M A;  3DL1 A;  2OXW A;  3EDZ A;  2AIG P;  4GQL A;  1XUD A;  4PKW A;  1BM6 A;  2OZR A;  1EAK A;  2MZH A;  4WF6 A;  4GWN A;  3RTS A;  4XM8 A;  1JK3 A;  3KEJ A;  3KEC A;  1ZS0 A;  4QKZ A;  3WV3 A;  4I35 A;  3HBV P;  3LQ0 A;  2JSD A;  3DWB A;  3LMC A;  1HTD A;  2E2D A;  1KUI A;  2OW0 A;  4PKQ A;  3N2U A;  1D7X A;  1K7Q A;  1PWW A;  1XFU A;  3K7N A;  4GWM A;  5I0L A;  4ZR5 A;  4PKU A;  2OXU A;  3LK8 A;  1BUV M;  1GXD A;  1ZTQ A;  2RJQ A;  2QPJ A;  4ILW D;  3LE9 A;  2X3C A;  3Q2H A;  830C A;  1J7N A;  3LJT A;  1KUH A;  3P24 A;  1JAO A;  2Y6C A;  4G9L A;  1GO8 P;  4H1Q A;  4XM7 A;  5CXA A;  3WV2 A;  1HOV A;  1A85 A;  1QJI A;  5I3M A;  2K9C A;  3HDB A;  2W15 A;  3LUM A;  3DSL A;  1O0Q A;  1Y0V A;  1XFW A;  2L0R A;  1YP1 A;  1I76 A;  3VTG A;  1BQO A;  1C8T A;  3KRY A;  2X7M A;  1GE6 A;  1CGL A;  1JAN A;  1G49 A;  3KWV C;  4H84 A;  4XCT A;  1JKY A;  3LEA A;  1UMT A;  1MMB A;  3TVC A;  1GKC A;  1SLM A;  1XFV A;  4GR0 A;  1S4B P;  2D1N A;  2WO9 A;  3USN A;  2N8R A;  5L7F A;  3LQB A;  3ZUK A;  3CKI A;  1IAB A;  3EWJ A;  1AKL A;  5D2B A;  1R1H A;  4L19 A;  4DPE A;  4IN9 A;  4GR3 A;  2WO8 A;  1UTT A;  1ZXC A;  4JP4 A;  1USN A;  1KAP P;  2YIG A;  2W0D A;  4GR8 A;  4PKT A;  4JPA A;  2OVZ A;  1AST A;  3DNG A;  1G05 A;  4HMA A;  1HV5 A;  4JIJ A;  5I12 A;  2J83 A;  1KUF A;  4FXY P;  1XUC A;  1ND1 A;  3RTT A;  2DDF A;  1EUB A;  1IAC A;  3GBO A;  1K7G A;  4GUY A;  2D1O A;  2A8H A;  3E8R A;  2OW1 A;  2MZI A;  4PKV A;  4WKE A;  1Y8J A;  1XFZ A;  3HY7 A;  1G9K A;  1UTZ A;  2SRT A;  3F17 A;  3B2Z A;  3V96 B;  3OHO A;  1ROS A;  4XBH A;  1ZVX A;  1B3D A;  1L6J A;  1I73 A;  3EDH A;  4R3V A;  5D7W A;  5JMY A;  4PKR A;  4WK7 A;  1PWP A;  3LJG A;  4L63 A;  3EDI A;  1GO7 P;  1QIA A;  3F16 A;  1BQQ M;  3F15 A;  1BSW A;  3LUN A;  2I47 A;  1FLS A;  1KBC A;  3NX7 A;  4XM6 A;  1QUA A;  2JIH A;  5CZM A;  1IAG A;  2W12 A;  1O0T A;  1OS9 A;  3LGP A;  2XS3 A;  3DPF A;  2AYK A;  4A7B A;  456C A;  3LIL A;  4H49 A;  3KMC A;  1B8Y A;  1CGF A;  2O3E A;  1AYK A;  4IJO A;  3LIK A;  4WKI A;  3AYU A;  3TSK A;  1QIB A;  1FM1 A;  2JNP A;  1GE7 A;  2DW0 A;  1RMZ A;  4L6T A;  2FV5 A;  2E3X A;  5D1S A;  1R1I A;  4H76 A;  3ELM A;  2OXZ A;  3B8Z A;  4PKS A;  3O2X A;  2X3B A;  2ERP A;  1BIW A;  5LAB A;  1K7I A;  1SRP A;  5B5P A;  5BPA A;  2DDY A;  5B5O A;  3LJZ A;  1ZXV A;  4J4M A;  1G4K A;  2ERO A;  1SAT A;  1DTH A;  1ATL A;  3G42 A;  2FV9 A;  3L0V A;  3L0T A;  3K7L A;  3TS4 A;  1SU3 A;  1IAE A;  1R1J A;  4A3W A;  1QIC A;  1CQR A;  5I4O A;  1YQY A;  1CGE A;  1MMR A;  2V4B A;  2OVX A;  4ON1 A;  1MNC A;  1HFC A;  1CIZ A;  2W13 A;  1MMP A;  3TT4 A;  3KEK A;  1IAD A;  2X3A A;  2YB9 A;  3HY9 A;  1DMT A;  3KHI A;  1JH1 A;  2TCL A;  2OI0 A;  3P1V A;  3N2V A;  4G0D A;  1KUK A;  1OMJ A;  2JT6 A;  1GE5 A;  1XUR A;  1PWV A;  2KRJ A;  5D1U A;  2CLT A;  4WZV A;  1JAP A;  1YCM A;  5I43 A;  3F18 A;  4GF1 A;  1OM7 A;  3F1A A;  4FXQ A;  4Q1L A;  1R55 A;  5CUH A;  2DW2 A;  4AXQ A;  5BOY A;  1H71 P;  3VI1 A;  2K2G A;  4AIG A;  1JAQ A; 
#chains in the Genus database with same CATH topology
 3U1R A;  4JA1 A;  1JIW P;  1AF0 A;  3LIR A;  3HDA P;  4DV8 A;  1A86 A;  2Y6D A;  1C7K A;  2O36 A;  4H3X A;  2WOA A;  1D8F A;  1JJ9 A;  1GKD A;  2PJT A;  2OW9 A;  2JT5 A;  3B92 A;  5I2Z A;  2MZE A;  3OHL A;  2USN A;  2W14 A;  3AIG A;  2MLR A;  2OW2 A;  5D3C A;  3HBU P;  1Y93 A;  1IAA A;  1WNI A;  2RJP A;  4H2E A;  3SHI A;  2POJ A;  3HB2 P;  966C A;  2HU6 A;  1D5J A;  4I03 A;  1MMQ A;  1BKC E;  1OO9 A;  5L79 A;  2Z2D A;  3WV1 A;  3O64 A;  2CKI A;  5D1T A;  1EB6 A;  2YUF A;  3BA0 A;  4AUO A;  1ZP5 A;  1JIZ A;  3ZVS A;  1Z3J A;  3I7G A;  1OS2 A;  2J0T A;  1QJJ A;  5BOT A;  3I7I A;  3AYK A;  4EFS A;  1XFX A;  1RM8 A;  1XFY A;  4H30 A;  3EHX A;  3ZXH A;  3F19 A;  1CAQ A;  2MLS A;  2XS4 A;  3HYG A;  4JQG A;  3EDG A;  1CK7 A;  3Q2G A;  1I1I P;  3G5C A;  4CTH A;  4FU4 A;  4IUW A;  4DD8 A;  1R54 A;  1BKC I;  2OY4 A;  1G12 A;  1YOU A;  5H8X A;  1OM8 A;  3EHY A;  2ERQ A;  1BZS A;  3DPE A;  4H82 A;  4HX3 A;  1OM6 A;  3LKA A;  1OZ9 A;  1BUD A;  4FVL A;  1CXV A;  1HY7 A;  1SLN A;  1SMP A;  3MA2 A;  1FBL A;  4AYK A;  4DF9 A;  1HFS A;  1C3I A;  2OY2 A;  3UVC A;  1UEA A;  3KME A;  1PWQ A;  2DW1 A;  1UMS A;  1BKC A;  1KUG A;  1Q3A A;  1PWU A;  1D8M A;  3DL1 A;  3DTI A;  2OXW A;  3EDZ A;  2AIG P;  4GQL A;  1XUD A;  4PKW A;  1BM6 A;  2OZR A;  1EAK A;  2MZH A;  4WF6 A;  4GWN A;  3RTS A;  4XM8 A;  1JK3 A;  3KEJ A;  3KEC A;  1ZS0 A;  4QKZ A;  3WV3 A;  4I35 A;  3HBV P;  3LQ0 A;  2JSD A;  3DWB A;  3LMC A;  1HTD A;  2E2D A;  1KUI A;  2OW0 A;  4PKQ A;  3N2U A;  1D7X A;  1K7Q A;  1PWW A;  1XFU A;  3K7N A;  4GWM A;  5I0L A;  4ZR5 A;  3DTE A;  4PKU A;  2OXU A;  3LK8 A;  1BUV M;  1GXD A;  1ZTQ A;  2RJQ A;  2QPJ A;  4ILW D;  3LE9 A;  2X3C A;  3Q2H A;  830C A;  1J7N A;  3LJT A;  1KUH A;  3P24 A;  1JAO A;  2Y6C A;  4G9L A;  1GO8 P;  4H1Q A;  4XM7 A;  5CXA A;  3WV2 A;  1HOV A;  1A85 A;  1QJI A;  5I3M A;  2K9C A;  3HDB A;  2W15 A;  3LUM A;  3DSL A;  1O0Q A;  1Y0V A;  1XFW A;  2L0R A;  1YP1 A;  1I76 A;  3VTG A;  1BQO A;  1C8T A;  3KRY A;  2X7M A;  1GE6 A;  1CGL A;  1JAN A;  1G49 A;  3KWV C;  4H84 A;  4XCT A;  1JKY A;  3LEA A;  1UMT A;  1MMB A;  3TVC A;  1GKC A;  1SLM A;  4L7A A;  1XFV A;  4GR0 A;  1S4B P;  2D1N A;  2WO9 A;  3USN A;  2N8R A;  5L7F A;  3LQB A;  3ZUK A;  3CKI A;  1IAB A;  3EWJ A;  1AKL A;  5D2B A;  1R1H A;  4L19 A;  4DPE A;  4IN9 A;  4GR3 A;  2WO8 A;  1UTT A;  1ZXC A;  4JP4 A;  1USN A;  1KAP P;  2YIG A;  2W0D A;  4GR8 A;  4PKT A;  4JPA A;  2OVZ A;  1AST A;  3DNG A;  1G05 A;  4HMA A;  1HV5 A;  4JIJ A;  5I12 A;  2J83 A;  1KUF A;  1XAX A;  4FXY P;  1XUC A;  1ND1 A;  3RTT A;  2DDF A;  1EUB A;  1IAC A;  3GBO A;  1K7G A;  4GUY A;  2D1O A;  2A8H A;  3E8R A;  2OW1 A;  2MZI A;  4PKV A;  4WKE A;  1Y8J A;  1XFZ A;  3HY7 A;  1G9K A;  1UTZ A;  2SRT A;  3F17 A;  3B2Z A;  3V96 B;  3OHO A;  1ROS A;  4XBH A;  1ZVX A;  1B3D A;  1L6J A;  1I73 A;  3EDH A;  4R3V A;  5D7W A;  5JMY A;  4PKR A;  4WK7 A;  1PWP A;  3LJG A;  4L63 A;  3EDI A;  1GO7 P;  1QIA A;  3F16 A;  1BQQ M;  3F15 A;  1BSW A;  3LUN A;  2I47 A;  1FLS A;  1KBC A;  3NX7 A;  4XM6 A;  1QUA A;  2JIH A;  5CZM A;  1IAG A;  2W12 A;  1O0T A;  1OS9 A;  3LGP A;  2XS3 A;  1XM5 A;  3DPF A;  2AYK A;  4A7B A;  456C A;  3LIL A;  4H49 A;  3KMC A;  1B8Y A;  1CGF A;  2O3E A;  1AYK A;  4IJO A;  3LIK A;  4WKI A;  3AYU A;  3TSK A;  1QIB A;  1FM1 A;  2JNP A;  1GE7 A;  2DW0 A;  1RMZ A;  4L6T A;  2FV5 A;  2E3X A;  5D1S A;  1R1I A;  4H76 A;  3ELM A;  2OXZ A;  3B8Z A;  4PKS A;  3O2X A;  2X3B A;  2ERP A;  1BIW A;  5LAB A;  1K7I A;  1SRP A;  5B5P A;  5BPA A;  2DDY A;  5B5O A;  3LJZ A;  1ZXV A;  4J4M A;  1G4K A;  2ERO A;  1SAT A;  1DTH A;  1ATL A;  3G42 A;  2FV9 A;  3L0V A;  3L0T A;  3K7L A;  3TS4 A;  1SU3 A;  1IAE A;  1R1J A;  4A3W A;  1QIC A;  1CQR A;  5I4O A;  1YQY A;  1CGE A;  1MMR A;  2V4B A;  2OVX A;  4ON1 A;  1MNC A;  1TVI A;  1HFC A;  1CIZ A;  2W13 A;  1MMP A;  3TT4 A;  3KEK A;  1IAD A;  3DTK A;  2X3A A;  2YB9 A;  3HY9 A;  1DMT A;  3KHI A;  1JH1 A;  2TCL A;  2OI0 A;  3P1V A;  3N2V A;  4G0D A;  1KUK A;  1OMJ A;  2JT6 A;  1GE5 A;  1XUR A;  1PWV A;  2KRJ A;  5D1U A;  2CLT A;  4WZV A;  1JAP A;  1YCM A;  5I43 A;  3F18 A;  4GF1 A;  1OM7 A;  3F1A A;  4FXQ A;  4Q1L A;  1R55 A;  5CUH A;  2DW2 A;  4AXQ A;  5BOY A;  1H71 P;  3VI1 A;  2K2G A;  4AIG A;  1JAQ A; 
#chains in the Genus database with same CATH homology
 3U1R A;  4JA1 A;  1JIW P;  1AF0 A;  3LIR A;  3HDA P;  4DV8 A;  1A86 A;  2Y6D A;  1C7K A;  2O36 A;  4H3X A;  2WOA A;  1D8F A;  1JJ9 A;  1GKD A;  2PJT A;  2OW9 A;  2JT5 A;  3B92 A;  5I2Z A;  2MZE A;  3OHL A;  2USN A;  2W14 A;  3AIG A;  2MLR A;  2OW2 A;  5D3C A;  3HBU P;  1Y93 A;  1IAA A;  1WNI A;  2RJP A;  4H2E A;  3SHI A;  2POJ A;  3HB2 P;  966C A;  2HU6 A;  1D5J A;  4I03 A;  1MMQ A;  1BKC E;  1OO9 A;  5L79 A;  2Z2D A;  3WV1 A;  3O64 A;  2CKI A;  5D1T A;  1EB6 A;  2YUF A;  3BA0 A;  4AUO A;  1ZP5 A;  1JIZ A;  3ZVS A;  1Z3J A;  3I7G A;  1OS2 A;  2J0T A;  1QJJ A;  5BOT A;  3I7I A;  3AYK A;  4EFS A;  1XFX A;  1RM8 A;  1XFY A;  4H30 A;  3EHX A;  3ZXH A;  3F19 A;  1CAQ A;  2MLS A;  2XS4 A;  3HYG A;  4JQG A;  3EDG A;  1CK7 A;  3Q2G A;  1I1I P;  3G5C A;  4CTH A;  4FU4 A;  4IUW A;  4DD8 A;  1R54 A;  1BKC I;  2OY4 A;  1G12 A;  1YOU A;  5H8X A;  1OM8 A;  3EHY A;  2ERQ A;  1BZS A;  3DPE A;  4H82 A;  4HX3 A;  1OM6 A;  3LKA A;  1BUD A;  4FVL A;  1CXV A;  1HY7 A;  1SLN A;  1SMP A;  3MA2 A;  1FBL A;  4AYK A;  4DF9 A;  1HFS A;  1C3I A;  2OY2 A;  3UVC A;  1UEA A;  3KME A;  1PWQ A;  2DW1 A;  1UMS A;  1BKC A;  1KUG A;  1Q3A A;  1PWU A;  1D8M A;  3DL1 A;  3DTI A;  2OXW A;  3EDZ A;  2AIG P;  4GQL A;  1XUD A;  4PKW A;  1BM6 A;  2OZR A;  1EAK A;  2MZH A;  4WF6 A;  4GWN A;  3RTS A;  4XM8 A;  1JK3 A;  3KEJ A;  3KEC A;  1ZS0 A;  4QKZ A;  3WV3 A;  4I35 A;  3HBV P;  3LQ0 A;  2JSD A;  3DWB A;  3LMC A;  1HTD A;  2E2D A;  1KUI A;  2OW0 A;  4PKQ A;  3N2U A;  1D7X A;  1K7Q A;  1PWW A;  1XFU A;  3K7N A;  4GWM A;  5I0L A;  4ZR5 A;  3DTE A;  4PKU A;  2OXU A;  3LK8 A;  1BUV M;  1GXD A;  1ZTQ A;  2RJQ A;  2QPJ A;  4ILW D;  3LE9 A;  2X3C A;  3Q2H A;  830C A;  1J7N A;  3LJT A;  1KUH A;  3P24 A;  1JAO A;  2Y6C A;  4G9L A;  1GO8 P;  4H1Q A;  4XM7 A;  5CXA A;  3WV2 A;  1HOV A;  1A85 A;  1QJI A;  5I3M A;  2K9C A;  3HDB A;  2W15 A;  3LUM A;  3DSL A;  1O0Q A;  1Y0V A;  1XFW A;  2L0R A;  1YP1 A;  1I76 A;  3VTG A;  1BQO A;  1C8T A;  3KRY A;  2X7M A;  1GE6 A;  1CGL A;  1JAN A;  1G49 A;  3KWV C;  4H84 A;  4XCT A;  1JKY A;  3LEA A;  1UMT A;  1MMB A;  3TVC A;  1GKC A;  1SLM A;  4L7A A;  1XFV A;  4GR0 A;  1S4B P;  2D1N A;  2WO9 A;  3USN A;  2N8R A;  5L7F A;  3LQB A;  3ZUK A;  3CKI A;  1IAB A;  3EWJ A;  1AKL A;  5D2B A;  1R1H A;  4L19 A;  4DPE A;  4IN9 A;  4GR3 A;  2WO8 A;  1UTT A;  1ZXC A;  4JP4 A;  1USN A;  1KAP P;  2YIG A;  2W0D A;  4GR8 A;  4PKT A;  4JPA A;  2OVZ A;  1AST A;  3DNG A;  1G05 A;  4HMA A;  1HV5 A;  4JIJ A;  5I12 A;  2J83 A;  1KUF A;  4FXY P;  1XUC A;  1ND1 A;  3RTT A;  2DDF A;  1EUB A;  1IAC A;  3GBO A;  1K7G A;  4GUY A;  2D1O A;  2A8H A;  3E8R A;  2OW1 A;  2MZI A;  4PKV A;  4WKE A;  1Y8J A;  1XFZ A;  3HY7 A;  1G9K A;  1UTZ A;  2SRT A;  3F17 A;  3B2Z A;  3V96 B;  3OHO A;  1ROS A;  4XBH A;  1ZVX A;  1B3D A;  1L6J A;  1I73 A;  3EDH A;  4R3V A;  5D7W A;  5JMY A;  4PKR A;  4WK7 A;  1PWP A;  3LJG A;  4L63 A;  3EDI A;  1GO7 P;  1QIA A;  3F16 A;  1BQQ M;  3F15 A;  1BSW A;  3LUN A;  2I47 A;  1FLS A;  1KBC A;  3NX7 A;  4XM6 A;  1QUA A;  2JIH A;  5CZM A;  1IAG A;  2W12 A;  1O0T A;  1OS9 A;  3LGP A;  2XS3 A;  3DPF A;  2AYK A;  4A7B A;  456C A;  3LIL A;  4H49 A;  3KMC A;  1B8Y A;  1CGF A;  2O3E A;  1AYK A;  4IJO A;  3LIK A;  4WKI A;  3AYU A;  3TSK A;  1QIB A;  1FM1 A;  2JNP A;  1GE7 A;  2DW0 A;  1RMZ A;  4L6T A;  2FV5 A;  2E3X A;  5D1S A;  1R1I A;  4H76 A;  3ELM A;  2OXZ A;  3B8Z A;  4PKS A;  3O2X A;  2X3B A;  2ERP A;  1BIW A;  5LAB A;  1K7I A;  1SRP A;  5B5P A;  5BPA A;  2DDY A;  5B5O A;  3LJZ A;  1ZXV A;  4J4M A;  1G4K A;  2ERO A;  1SAT A;  1DTH A;  1ATL A;  3G42 A;  2FV9 A;  3L0V A;  3L0T A;  3K7L A;  3TS4 A;  1SU3 A;  1IAE A;  1R1J A;  4A3W A;  1QIC A;  1CQR A;  5I4O A;  1YQY A;  1CGE A;  1MMR A;  2V4B A;  2OVX A;  4ON1 A;  1MNC A;  1HFC A;  1CIZ A;  2W13 A;  1MMP A;  3TT4 A;  3KEK A;  1IAD A;  3DTK A;  2X3A A;  2YB9 A;  3HY9 A;  1DMT A;  3KHI A;  1JH1 A;  2TCL A;  2OI0 A;  3P1V A;  3N2V A;  4G0D A;  1KUK A;  1OMJ A;  2JT6 A;  1GE5 A;  1XUR A;  1PWV A;  2KRJ A;  5D1U A;  2CLT A;  4WZV A;  1JAP A;  1YCM A;  5I43 A;  3F18 A;  4GF1 A;  1OM7 A;  3F1A A;  4FXQ A;  4Q1L A;  1R55 A;  5CUH A;  2DW2 A;  4AXQ A;  5BOY A;  1H71 P;  3VI1 A;  2K2G A;  4AIG A;  1JAQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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