3HY7A

Crystal structure of the catalytic domain of adamts-5 in complex with marimastat
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
217
structure length
217
Chain Sequence
SRARQVELLLVADASMARKYGRGLQHYLLTLASIANRLYSHASIENHIRLAVVKVVVLGDKDKSLEVSKNAATTLKNFCKWQHQHNQLGDDHEEHYDAAILFTREDLCGHHSCDTLGMADVGTICSPERSCAVIEDDGLHAAFTVAHEIGHLLGLSHDDSKFCEETFGSTEDKRLMSSILTSIDASKPWSKCTSATITEFLDDGHGNCLLDLPRKQI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural and inhibition analysis reveals the mechanism of selectivity of a series of aggrecanase inhibitors
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords A disintegrin and metalloproteinase with thrombospondin moti
total genus 73
structure length 217
sequence length 217
chains with identical sequence B
ec nomenclature ec 3.4.24.-:
pdb deposition date 2009-06-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01421 Reprolysin Reprolysin (M12B) family zinc metalloprotease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3hy7A00
3WV2A 1CGLA 4FXYP 3EDZA 3VTGA 4FU4A 3ZUKA 2EROA 1UMTA 2POJA 1EUBA 1BZSA 2OW0A 1ROSA 1R55A 4PKRA 3WV1A 1OM6A 3DL1A 1PWWA 4H3XA 3MA2A 1KUIA 5B5OA 3VI1A 1JJ9A 2QPJA 2Y6CA 1SATA 1D7XA 3BA0A 4WF6A 3DSLA 4ZR5A 4A7BA 1GE6A 1JKYA 3DNGA 3LUMA 1OMJA 1CIZA 1YCMA 1BM6A 4AUOA 1UTZA 1AYKA 3Q2GA 3TVCA 2J83A 1PWVA 1IAGA 3F16A 2ERPA 4XBHA 3KHIA 1JK3A 4PKVA 2FV9A 2K9CA 2ERQA 1C8TA 1XUCA 4HX3A 1D8FA 3LE9A 1XFUA 3EHXA 2W13A 4XM8A 4G0DA 1Y8JA 2OVXA 1QIAA 4GUYA 1USNA 4GR0A 1C3IA 2RJQA 1BQQM 1JH1A 3HYGA 2Y6DA 1G12A 3B2ZA 3DPEA 1UTTA 4ON1A 1CQRA 4R3VA 5I2ZA 1QUAA 3LJZA 3KEJA 1BKCA 3LMCA 1G05A 4FXQA 1AF0A 3HY9A 4JPAA 966CA 4XCTA 1JIWP 3B8ZA 1BUVM 1L6JA 3LK8A 4H30A 1XFXA 1G49A 1OM7A 3N2UA 2DW2A 2HU6A 3LQ0A 1JAPA 3CKIA 3L0TA 4JIJA 3LIRA 4JP4A 3ZXHA 4H1QA 1SLNA 4JA1A 2I47A 1GE5A 1GKCA 4G9LA 3K7NA 5CZMA 1CGEA 3HBVP 2W14A 3GBOA 5I12A 2K2GA 1BQOA 4GWNA 1FBLA 2YB9A 3O2XA 5LABA 2JT6A 5D7WA 5L79A 2JT5A 2E2DA 4AYKA 1PWQA 3P1VA 5L7FA 1YQYA 4L6TA 3G42A 2X7MA 2XS3A 3HY7A 4ILWD 3V96B 3I7GA 3HB2P 2X3BA 2YIGA 1UMSA 1ZXVA 3F18A 5B5PA 1GE7A 1OO9A 3AIGA 4IJOA 4H84A 1JAOA 1FLSA 3LQBA 1CGFA 4H49A 2FV5A 3UVCA 5D1UA 1CXVA 2WOAA 5I4OA 1Y93A 2PJTA 3AYKA 1KUFA 1GO7P 4HMAA 1KUHA 1ZP5A 1AKLA 3LUNA 3USNA 1YP1A 4FVLA 4DD8A 4GF1A 3LIKA 2Z2DA 1O0QA 3HBUP 3DWBA 3KMCA 4PKUA 1XFVA 1PWUA 1SRPA 2KRJA 5BOYA 5I0LA 3L0VA 2OW9A 2X3AA 4PKQA 1SLMA 2J0TA 4PKTA 5I3MA 1DTHA 3LGPA 2MLSA 5CUHA 2W12A 1K7GA 1MMPA 1I76A 5CXAA 5D2BA 3ZVSA 2OY4A 2JSDA 1ASTA 1KUGA 1C7KA 1QJJA 1ND1A 1BKCI 1MNCA 2MZHA 3EDHA 830CA 1KBCA 5BPAA 1GXDA 1OM8A 3Q2HA 1G9KA 2JIHA 3OHLA 3OHOA 4H76A 4GQLA 3HDBA 3NX7A 1HFSA 4Q1LA 1ZS0A 3EDGA 1A85A 1A86A 1HY7A 3P24A 4H2EA 2DW1A 2V4BA 2OXUA 1PWPA 3O64A 1HV5A 1MMBA 2XS4A 3ELMA 1XFYA 4GR3A 5BOTA 2D1OA 3G5CA 3E8RA 1CAQA 2OXWA 1H71P 2SRTA 1HFCA 3LKAA 1DMTA 2O3EA 4GWMA 3KMEA 1KUKA 4J4MA 4DPEA 4PKSA 1HOVA 4XM7A 1IADA 2O36A 4AXQA 1QJIA 1O0TA 1QIBA 2JNPA 2X3CA 5D1SA 5D1TA 3KWVC 3U1RA 1K7IA 2MLRA 1BKCE 3EDIA 1GKDA 4CTHA 4A3WA 1RMZA 456CA 4EFSA 1ZVXA 2DDYA 3TS4A 1R1IA 1XUDA 4QKZA 1BUDA 1R1JA 1S4BP 2A8HA 1B8YA 1ATLA 2OY2A 1XFWA 2DDFA 1MMRA 1FM1A 1CK7A 1Y0VA 1B3DA 2WO8A 1EAKA 1GO8P 1KAPP 3EHYA 3LEAA 4H82A 3KECA 2WO9A 1Q3AA 3K7LA 2RJPA 1K7QA 4PKWA 3LILA 2CLTA 1UEAA 2CKIA 1I73A 3WV3A 4GR8A 1XFZA 4XM6A 3EWJA 2DW0A 3F1AA 1IAEA 2E3XA 1R1HA 3I7IA 2OI0A 1EB6A 2USNA 3RTTA 1IAAA 3TT4A 1Z3JA 2OZRA 1I1IP 2D1NA 1R54A 3RTSA 4I03A 2TCLA 1XURA 2L0RA 3KEKA 4AIGA 1OS2A 1RM8A 5I43A 3F15A 4IN9A 1D8MA 3LJGA 1WNIA 1J7NA 3HDAP 4WKEA 1IACA 4DF9A 4I35A 2N8RA 1QICA 2OW2A 1BSWA 1JANA 1MMQA 3KRYA 5H8XA 1G4KA 4WK7A 4DV8A 1IABA 1YOUA 3LJTA 2OVZA 1D5JA 1ZXCA 3F17A 1SMPA 3DPFA 1OS9A 1BIWA 2W0DA 1HTDA 2AIGP 2OW1A 3B92A 4JQGA 2MZIA 3SHIA 1JAQA 4WZVA 2MZEA 3AYUA 2OXZA 4L63A 3N2VA 4WKIA 4L19A 5JMYA 4IUWA 3TSKA 1ZTQA 3F19A 2W15A 5D3CA 1JIZA 1SU3A 2AYKA
chains in the Genus database with same CATH superfamily
3WV2A 1CGLA 4FXYP 3EDZA 3VTGA 4FU4A 3ZUKA 2EROA 1UMTA 2POJA 1EUBA 1BZSA 2OW0A 1ROSA 1R55A 4PKRA 3WV1A 1OM6A 3DL1A 1PWWA 4H3XA 3MA2A 1KUIA 5B5OA 3VI1A 1JJ9A 2QPJA 2Y6CA 1SATA 1D7XA 3BA0A 4WF6A 3DSLA 4ZR5A 4A7BA 1GE6A 1JKYA 3DNGA 3LUMA 1OMJA 1CIZA 1YCMA 1BM6A 4AUOA 1UTZA 1AYKA 3Q2GA 3TVCA 2J83A 2YUFA 1PWVA 1IAGA 3F16A 2ERPA 4XBHA 3KHIA 1JK3A 4PKVA 2FV9A 2K9CA 2ERQA 1C8TA 1XUCA 4HX3A 1D8FA 3LE9A 1XFUA 3EHXA 2W13A 4XM8A 4G0DA 1Y8JA 2OVXA 1QIAA 4GUYA 1USNA 4GR0A 1C3IA 2RJQA 1BQQM 1JH1A 3HYGA 2Y6DA 1G12A 3B2ZA 3DPEA 1UTTA 4ON1A 1CQRA 4R3VA 5I2ZA 1QUAA 3LJZA 3KEJA 1BKCA 3LMCA 1G05A 4FXQA 1AF0A 3HY9A 4JPAA 966CA 4XCTA 1JIWP 3B8ZA 1BUVM 1L6JA 3LK8A 4H30A 1XFXA 1G49A 1OM7A 3N2UA 2DW2A 2HU6A 3LQ0A 1JAPA 3CKIA 3L0TA 4JIJA 3LIRA 4JP4A 3ZXHA 4H1QA 1SLNA 4JA1A 2I47A 1GE5A 1GKCA 4G9LA 3K7NA 5CZMA 1CGEA 3HBVP 2W14A 3GBOA 5I12A 2K2GA 1BQOA 4GWNA 1FBLA 2YB9A 3O2XA 5LABA 2JT6A 5D7WA 5L79A 1OZ9A 2JT5A 2E2DA 4AYKA 1XM5A 1PWQA 3P1VA 5L7FA 1YQYA 4L6TA 3G42A 2X7MA 2XS3A 3HY7A 4ILWD 3V96B 3I7GA 3HB2P 2X3BA 2YIGA 1UMSA 1ZXVA 3F18A 3DTEA 5B5PA 1GE7A 1OO9A 3AIGA 4IJOA 4H84A 1JAOA 1FLSA 3LQBA 1CGFA 4H49A 2FV5A 3UVCA 5D1UA 1CXVA 2WOAA 5I4OA 1Y93A 2PJTA 3AYKA 1KUFA 1GO7P 4HMAA 1KUHA 1ZP5A 1AKLA 3LUNA 3USNA 1YP1A 4FVLA 4L7AA 4DD8A 4GF1A 3LIKA 2Z2DA 1O0QA 3HBUP 3DWBA 3KMCA 4PKUA 1XFVA 1PWUA 1SRPA 2KRJA 5BOYA 5I0LA 3L0VA 2OW9A 2X3AA 4PKQA 1SLMA 2J0TA 4PKTA 5I3MA 1DTHA 3LGPA 2MLSA 5CUHA 2W12A 1K7GA 1MMPA 1I76A 5CXAA 5D2BA 3ZVSA 2OY4A 2JSDA 1ASTA 1KUGA 1C7KA 1QJJA 3DTKA 1ND1A 1BKCI 1MNCA 2MZHA 3EDHA 830CA 1KBCA 5BPAA 1GXDA 1OM8A 3Q2HA 1G9KA 2JIHA 3OHLA 3OHOA 4H76A 4GQLA 3HDBA 3NX7A 1HFSA 4Q1LA 1ZS0A 3EDGA 1A85A 1A86A 1HY7A 1XAXA 3P24A 4H2EA 2DW1A 2V4BA 2OXUA 1PWPA 3O64A 1HV5A 1MMBA 2XS4A 3ELMA 1TVIA 1XFYA 4GR3A 5BOTA 2D1OA 3G5CA 3E8RA 1CAQA 2OXWA 1H71P 2SRTA 1HFCA 3LKAA 1DMTA 2O3EA 4GWMA 3KMEA 1KUKA 4J4MA 4DPEA 4PKSA 1HOVA 4XM7A 1IADA 2O36A 4AXQA 1QJIA 1O0TA 1QIBA 2JNPA 2X3CA 5D1SA 5D1TA 3KWVC 3U1RA 1K7IA 2MLRA 3DTIA 1BKCE 3EDIA 1GKDA 4CTHA 4A3WA 1RMZA 456CA 4EFSA 1ZVXA 2DDYA 3TS4A 1R1IA 1XUDA 4QKZA 1BUDA 1R1JA 1S4BP 2A8HA 1B8YA 1ATLA 2OY2A 1XFWA 2DDFA 1MMRA 1FM1A 1CK7A 1Y0VA 1B3DA 2WO8A 1EAKA 1GO8P 1KAPP 3EHYA 3LEAA 4H82A 3KECA 2WO9A 1Q3AA 3K7LA 2RJPA 1K7QA 4PKWA 3LILA 2CLTA 1UEAA 2CKIA 1I73A 3WV3A 4GR8A 1XFZA 4XM6A 3EWJA 2DW0A 3F1AA 1IAEA 2E3XA 1R1HA 3I7IA 2OI0A 1EB6A 2USNA 3RTTA 1IAAA 3TT4A 1Z3JA 2OZRA 1I1IP 2D1NA 1R54A 3RTSA 4I03A 2TCLA 1XURA 2L0RA 3KEKA 4AIGA 1OS2A 1RM8A 5I43A 3F15A 4IN9A 1D8MA 3LJGA 1WNIA 1J7NA 3HDAP 4WKEA 1IACA 4DF9A 4I35A 2N8RA 1QICA 2OW2A 1BSWA 1JANA 1MMQA 3KRYA 5H8XA 1G4KA 4WK7A 4DV8A 1IABA 1YOUA 3LJTA 2OVZA 1D5JA 1ZXCA 3F17A 1SMPA 3DPFA 1OS9A 1BIWA 2W0DA 1HTDA 2AIGP 2OW1A 3B92A 4JQGA 2MZIA 3SHIA 1JAQA 4WZVA 2MZEA 3AYUA 2OXZA 4L63A 3N2VA 4WKIA 4L19A 5JMYA 4IUWA 3TSKA 1ZTQA 3F19A 2W15A 5D3CA 1JIZA 1SU3A 2AYKA
chains in the Genus database with same CATH topology
3WV2A 1CGLA 4FXYP 3EDZA 3VTGA 4FU4A 3ZUKA 2EROA 1UMTA 2POJA 1EUBA 1BZSA 2OW0A 1ROSA 1R55A 4PKRA 3WV1A 1OM6A 3DL1A 1PWWA 4H3XA 3MA2A 1KUIA 5B5OA 3VI1A 1JJ9A 2QPJA 2Y6CA 1SATA 1D7XA 3BA0A 4WF6A 3DSLA 4ZR5A 4A7BA 1GE6A 1JKYA 3DNGA 3LUMA 1OMJA 1CIZA 1YCMA 1BM6A 4AUOA 1UTZA 1AYKA 3Q2GA 3TVCA 2J83A 2YUFA 1PWVA 1IAGA 3F16A 2ERPA 4XBHA 3KHIA 1JK3A 4PKVA 2FV9A 2K9CA 2ERQA 1C8TA 1XUCA 4HX3A 1D8FA 3LE9A 1XFUA 3EHXA 2W13A 4XM8A 4G0DA 1Y8JA 2OVXA 1QIAA 4GUYA 1USNA 4GR0A 1C3IA 2RJQA 1BQQM 1JH1A 3HYGA 2Y6DA 1G12A 3B2ZA 3DPEA 1UTTA 4ON1A 1CQRA 4R3VA 5I2ZA 1QUAA 3LJZA 3KEJA 1BKCA 3LMCA 1G05A 4FXQA 1AF0A 3HY9A 4JPAA 966CA 4XCTA 1JIWP 3B8ZA 1BUVM 1L6JA 3LK8A 4H30A 1XFXA 1G49A 1OM7A 3N2UA 2DW2A 2HU6A 3LQ0A 1JAPA 3CKIA 3L0TA 4JIJA 3LIRA 4JP4A 3ZXHA 4H1QA 1SLNA 4JA1A 2I47A 1GE5A 1GKCA 4G9LA 3K7NA 5CZMA 1CGEA 3HBVP 2W14A 3GBOA 5I12A 2K2GA 1BQOA 4GWNA 1FBLA 2YB9A 3O2XA 5LABA 2JT6A 5D7WA 5L79A 2JT5A 2E2DA 4AYKA 1PWQA 3P1VA 5L7FA 1YQYA 4L6TA 3G42A 2X7MA 2XS3A 3HY7A 4ILWD 3V96B 3I7GA 3HB2P 2X3BA 2YIGA 1UMSA 1ZXVA 3F18A 3DTEA 5B5PA 1GE7A 1OO9A 3AIGA 4IJOA 4H84A 1JAOA 1FLSA 3LQBA 1CGFA 4H49A 2FV5A 3UVCA 5D1UA 1CXVA 2WOAA 5I4OA 1Y93A 2PJTA 3AYKA 1KUFA 1GO7P 4HMAA 1KUHA 1ZP5A 1AKLA 3LUNA 3USNA 1YP1A 4FVLA 4L7AA 4DD8A 4GF1A 3LIKA 2Z2DA 1O0QA 3HBUP 3DWBA 3KMCA 4PKUA 1XFVA 1PWUA 1SRPA 2KRJA 5BOYA 5I0LA 3L0VA 2OW9A 2X3AA 4PKQA 1SLMA 2J0TA 4PKTA 5I3MA 1DTHA 3LGPA 2MLSA 5CUHA 2W12A 1K7GA 1MMPA 1I76A 5CXAA 5D2BA 3ZVSA 2OY4A 2JSDA 1ASTA 1KUGA 1C7KA 1QJJA 3DTKA 1ND1A 1BKCI 1MNCA 2MZHA 3EDHA 830CA 1KBCA 5BPAA 1GXDA 1OM8A 3Q2HA 1G9KA 2JIHA 3OHLA 3OHOA 4H76A 4GQLA 3HDBA 3NX7A 1HFSA 4Q1LA 1ZS0A 3EDGA 1A85A 1A86A 1HY7A 3P24A 4H2EA 2DW1A 2V4BA 2OXUA 1PWPA 3O64A 1HV5A 1MMBA 2XS4A 3ELMA 1XFYA 4GR3A 5BOTA 2D1OA 3G5CA 3E8RA 1CAQA 2OXWA 1H71P 2SRTA 1HFCA 3LKAA 1DMTA 2O3EA 4GWMA 3KMEA 1KUKA 4J4MA 4DPEA 4PKSA 1HOVA 4XM7A 1IADA 2O36A 4AXQA 1QJIA 1O0TA 1QIBA 2JNPA 2X3CA 5D1SA 5D1TA 3KWVC 3U1RA 1K7IA 2MLRA 3DTIA 1BKCE 3EDIA 1GKDA 4CTHA 4A3WA 1RMZA 456CA 4EFSA 1ZVXA 2DDYA 3TS4A 1R1IA 1XUDA 4QKZA 1BUDA 1R1JA 1S4BP 2A8HA 1B8YA 1ATLA 2OY2A 1XFWA 2DDFA 1MMRA 1FM1A 1CK7A 1Y0VA 1B3DA 2WO8A 1EAKA 1GO8P 1KAPP 3EHYA 3LEAA 4H82A 3KECA 2WO9A 1Q3AA 3K7LA 2RJPA 1K7QA 4PKWA 3LILA 2CLTA 1UEAA 2CKIA 1I73A 3WV3A 4GR8A 1XFZA 4XM6A 3EWJA 2DW0A 3F1AA 1IAEA 2E3XA 1R1HA 3I7IA 2OI0A 1EB6A 2USNA 3RTTA 1IAAA 3TT4A 1Z3JA 2OZRA 1I1IP 2D1NA 1R54A 3RTSA 4I03A 2TCLA 1XURA 2L0RA 3KEKA 4AIGA 1OS2A 1RM8A 5I43A 3F15A 4IN9A 1D8MA 3LJGA 1WNIA 1J7NA 3HDAP 4WKEA 1IACA 4DF9A 4I35A 2N8RA 1QICA 2OW2A 1BSWA 1JANA 1MMQA 3KRYA 5H8XA 1G4KA 4WK7A 4DV8A 1IABA 1YOUA 3LJTA 2OVZA 1D5JA 1ZXCA 3F17A 1SMPA 3DPFA 1OS9A 1BIWA 2W0DA 1HTDA 2AIGP 2OW1A 3B92A 4JQGA 2MZIA 3SHIA 1JAQA 4WZVA 2MZEA 3AYUA 2OXZA 4L63A 3N2VA 4WKIA 4L19A 5JMYA 4IUWA 3TSKA 1ZTQA 3F19A 2W15A 5D3CA 1JIZA 1SU3A 2AYKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3WV2 A;  1CGL A;  4FXY P;  3EDZ A;  3VTG A;  4FU4 A;  3ZUK A;  2ERO A;  1UMT A;  2POJ A;  1EUB A;  1BZS A;  2OW0 A;  1ROS A;  1R55 A;  4PKR A;  3WV1 A;  1OM6 A;  3DL1 A;  1PWW A;  4H3X A;  3MA2 A;  1KUI A;  5B5O A;  3VI1 A;  1JJ9 A;  2QPJ A;  2Y6C A;  1SAT A;  1D7X A;  3BA0 A;  4WF6 A;  3DSL A;  4ZR5 A;  4A7B A;  1GE6 A;  1JKY A;  3DNG A;  3LUM A;  1OMJ A;  1CIZ A;  1YCM A;  1BM6 A;  4AUO A;  1UTZ A;  1AYK A;  3Q2G A;  3TVC A;  2J83 A;  1PWV A;  1IAG A;  3F16 A;  2ERP A;  4XBH A;  3KHI A;  1JK3 A;  4PKV A;  2FV9 A;  2K9C A;  2ERQ A;  1C8T A;  1XUC A;  4HX3 A;  1D8F A;  3LE9 A;  1XFU A;  3EHX A;  2W13 A;  4XM8 A;  4G0D A;  1Y8J A;  2OVX A;  1QIA A;  4GUY A;  1USN A;  4GR0 A;  1C3I A;  2RJQ A;  1BQQ M;  1JH1 A;  3HYG A;  2Y6D A;  1G12 A;  3B2Z A;  3DPE A;  1UTT A;  4ON1 A;  1CQR A;  4R3V A;  5I2Z A;  1QUA A;  3LJZ A;  3KEJ A;  1BKC A;  3LMC A;  1G05 A;  4FXQ A;  1AF0 A;  3HY9 A;  4JPA A;  966C A;  4XCT A;  1JIW P;  3B8Z A;  1BUV M;  1L6J A;  3LK8 A;  4H30 A;  1XFX A;  1G49 A;  1OM7 A;  3N2U A;  2DW2 A;  2HU6 A;  3LQ0 A;  1JAP A;  3CKI A;  3L0T A;  4JIJ A;  3LIR A;  4JP4 A;  3ZXH A;  4H1Q A;  1SLN A;  4JA1 A;  2I47 A;  1GE5 A;  1GKC A;  4G9L A;  3K7N A;  5CZM A;  1CGE A;  3HBV P;  2W14 A;  3GBO A;  5I12 A;  2K2G A;  1BQO A;  4GWN A;  1FBL A;  2YB9 A;  3O2X A;  5LAB A;  2JT6 A;  5D7W A;  5L79 A;  2JT5 A;  2E2D A;  4AYK A;  1PWQ A;  3P1V A;  5L7F A;  1YQY A;  4L6T A;  3G42 A;  2X7M A;  2XS3 A;  3HY7 A;  4ILW D;  3V96 B;  3I7G A;  3HB2 P;  2X3B A;  2YIG A;  1UMS A;  1ZXV A;  3F18 A;  5B5P A;  1GE7 A;  1OO9 A;  3AIG A;  4IJO A;  4H84 A;  1JAO A;  1FLS A;  3LQB A;  1CGF A;  4H49 A;  2FV5 A;  3UVC A;  5D1U A;  1CXV A;  2WOA A;  5I4O A;  1Y93 A;  2PJT A;  3AYK A;  1KUF A;  1GO7 P;  4HMA A;  1KUH A;  1ZP5 A;  1AKL A;  3LUN A;  3USN A;  1YP1 A;  4FVL A;  4DD8 A;  4GF1 A;  3LIK A;  2Z2D A;  1O0Q A;  3HBU P;  3DWB A;  3KMC A;  4PKU A;  1XFV A;  1PWU A;  1SRP A;  2KRJ A;  5BOY A;  5I0L A;  3L0V A;  2OW9 A;  2X3A A;  4PKQ A;  1SLM A;  2J0T A;  4PKT A;  5I3M A;  1DTH A;  3LGP A;  2MLS A;  5CUH A;  2W12 A;  1K7G A;  1MMP A;  1I76 A;  5CXA A;  5D2B A;  3ZVS A;  2OY4 A;  2JSD A;  1AST A;  1KUG A;  1C7K A;  1QJJ A;  1ND1 A;  1BKC I;  1MNC A;  2MZH A;  3EDH A;  830C A;  1KBC A;  5BPA A;  1GXD A;  1OM8 A;  3Q2H A;  1G9K A;  2JIH A;  3OHL A;  3OHO A;  4H76 A;  4GQL A;  3HDB A;  3NX7 A;  1HFS A;  4Q1L A;  1ZS0 A;  3EDG A;  1A85 A;  1A86 A;  1HY7 A;  3P24 A;  4H2E A;  2DW1 A;  2V4B A;  2OXU A;  1PWP A;  3O64 A;  1HV5 A;  1MMB A;  2XS4 A;  3ELM A;  1XFY A;  4GR3 A;  5BOT A;  2D1O A;  3G5C A;  3E8R A;  1CAQ A;  2OXW A;  1H71 P;  2SRT A;  1HFC A;  3LKA A;  1DMT A;  2O3E A;  4GWM A;  3KME A;  1KUK A;  4J4M A;  4DPE A;  4PKS A;  1HOV A;  4XM7 A;  1IAD A;  2O36 A;  4AXQ A;  1QJI A;  1O0T A;  1QIB A;  2JNP A;  2X3C A;  5D1S A;  5D1T A;  3KWV C;  3U1R A;  1K7I A;  2MLR A;  1BKC E;  3EDI A;  1GKD A;  4CTH A;  4A3W A;  1RMZ A;  456C A;  4EFS A;  1ZVX A;  2DDY A;  3TS4 A;  1R1I A;  1XUD A;  4QKZ A;  1BUD A;  1R1J A;  1S4B P;  2A8H A;  1B8Y A;  1ATL A;  2OY2 A;  1XFW A;  2DDF A;  1MMR A;  1FM1 A;  1CK7 A;  1Y0V A;  1B3D A;  2WO8 A;  1EAK A;  1GO8 P;  1KAP P;  3EHY A;  3LEA A;  4H82 A;  3KEC A;  2WO9 A;  1Q3A A;  3K7L A;  2RJP A;  1K7Q A;  4PKW A;  3LIL A;  2CLT A;  1UEA A;  2CKI A;  1I73 A;  3WV3 A;  4GR8 A;  1XFZ A;  4XM6 A;  3EWJ A;  2DW0 A;  3F1A A;  1IAE A;  2E3X A;  1R1H A;  3I7I A;  2OI0 A;  1EB6 A;  2USN A;  3RTT A;  1IAA A;  3TT4 A;  1Z3J A;  2OZR A;  1I1I P;  2D1N A;  1R54 A;  3RTS A;  4I03 A;  2TCL A;  1XUR A;  2L0R A;  3KEK A;  4AIG A;  1OS2 A;  1RM8 A;  5I43 A;  3F15 A;  4IN9 A;  1D8M A;  3LJG A;  1WNI A;  1J7N A;  3HDA P;  4WKE A;  1IAC A;  4DF9 A;  4I35 A;  2N8R A;  1QIC A;  2OW2 A;  1BSW A;  1JAN A;  1MMQ A;  3KRY A;  5H8X A;  1G4K A;  4WK7 A;  4DV8 A;  1IAB A;  1YOU A;  3LJT A;  2OVZ A;  1D5J A;  1ZXC A;  3F17 A;  1SMP A;  3DPF A;  1OS9 A;  1BIW A;  2W0D A;  1HTD A;  2AIG P;  2OW1 A;  3B92 A;  4JQG A;  2MZI A;  3SHI A;  1JAQ A;  4WZV A;  2MZE A;  3AYU A;  2OXZ A;  4L63 A;  3N2V A;  4WKI A;  4L19 A;  5JMY A;  4IUW A;  3TSK A;  1ZTQ A;  3F19 A;  2W15 A;  5D3C A;  1JIZ A;  1SU3 A;  2AYK A; 
#chains in the Genus database with same CATH topology
 3WV2 A;  1CGL A;  4FXY P;  3EDZ A;  3VTG A;  4FU4 A;  3ZUK A;  2ERO A;  1UMT A;  2POJ A;  1EUB A;  1BZS A;  2OW0 A;  1ROS A;  1R55 A;  4PKR A;  3WV1 A;  1OM6 A;  3DL1 A;  1PWW A;  4H3X A;  3MA2 A;  1KUI A;  5B5O A;  3VI1 A;  1JJ9 A;  2QPJ A;  2Y6C A;  1SAT A;  1D7X A;  3BA0 A;  4WF6 A;  3DSL A;  4ZR5 A;  4A7B A;  1GE6 A;  1JKY A;  3DNG A;  3LUM A;  1OMJ A;  1CIZ A;  1YCM A;  1BM6 A;  4AUO A;  1UTZ A;  1AYK A;  3Q2G A;  3TVC A;  2J83 A;  2YUF A;  1PWV A;  1IAG A;  3F16 A;  2ERP A;  4XBH A;  3KHI A;  1JK3 A;  4PKV A;  2FV9 A;  2K9C A;  2ERQ A;  1C8T A;  1XUC A;  4HX3 A;  1D8F A;  3LE9 A;  1XFU A;  3EHX A;  2W13 A;  4XM8 A;  4G0D A;  1Y8J A;  2OVX A;  1QIA A;  4GUY A;  1USN A;  4GR0 A;  1C3I A;  2RJQ A;  1BQQ M;  1JH1 A;  3HYG A;  2Y6D A;  1G12 A;  3B2Z A;  3DPE A;  1UTT A;  4ON1 A;  1CQR A;  4R3V A;  5I2Z A;  1QUA A;  3LJZ A;  3KEJ A;  1BKC A;  3LMC A;  1G05 A;  4FXQ A;  1AF0 A;  3HY9 A;  4JPA A;  966C A;  4XCT A;  1JIW P;  3B8Z A;  1BUV M;  1L6J A;  3LK8 A;  4H30 A;  1XFX A;  1G49 A;  1OM7 A;  3N2U A;  2DW2 A;  2HU6 A;  3LQ0 A;  1JAP A;  3CKI A;  3L0T A;  4JIJ A;  3LIR A;  4JP4 A;  3ZXH A;  4H1Q A;  1SLN A;  4JA1 A;  2I47 A;  1GE5 A;  1GKC A;  4G9L A;  3K7N A;  5CZM A;  1CGE A;  3HBV P;  2W14 A;  3GBO A;  5I12 A;  2K2G A;  1BQO A;  4GWN A;  1FBL A;  2YB9 A;  3O2X A;  5LAB A;  2JT6 A;  5D7W A;  5L79 A;  1OZ9 A;  2JT5 A;  2E2D A;  4AYK A;  1XM5 A;  1PWQ A;  3P1V A;  5L7F A;  1YQY A;  4L6T A;  3G42 A;  2X7M A;  2XS3 A;  3HY7 A;  4ILW D;  3V96 B;  3I7G A;  3HB2 P;  2X3B A;  2YIG A;  1UMS A;  1ZXV A;  3F18 A;  3DTE A;  5B5P A;  1GE7 A;  1OO9 A;  3AIG A;  4IJO A;  4H84 A;  1JAO A;  1FLS A;  3LQB A;  1CGF A;  4H49 A;  2FV5 A;  3UVC A;  5D1U A;  1CXV A;  2WOA A;  5I4O A;  1Y93 A;  2PJT A;  3AYK A;  1KUF A;  1GO7 P;  4HMA A;  1KUH A;  1ZP5 A;  1AKL A;  3LUN A;  3USN A;  1YP1 A;  4FVL A;  4L7A A;  4DD8 A;  4GF1 A;  3LIK A;  2Z2D A;  1O0Q A;  3HBU P;  3DWB A;  3KMC A;  4PKU A;  1XFV A;  1PWU A;  1SRP A;  2KRJ A;  5BOY A;  5I0L A;  3L0V A;  2OW9 A;  2X3A A;  4PKQ A;  1SLM A;  2J0T A;  4PKT A;  5I3M A;  1DTH A;  3LGP A;  2MLS A;  5CUH A;  2W12 A;  1K7G A;  1MMP A;  1I76 A;  5CXA A;  5D2B A;  3ZVS A;  2OY4 A;  2JSD A;  1AST A;  1KUG A;  1C7K A;  1QJJ A;  3DTK A;  1ND1 A;  1BKC I;  1MNC A;  2MZH A;  3EDH A;  830C A;  1KBC A;  5BPA A;  1GXD A;  1OM8 A;  3Q2H A;  1G9K A;  2JIH A;  3OHL A;  3OHO A;  4H76 A;  4GQL A;  3HDB A;  3NX7 A;  1HFS A;  4Q1L A;  1ZS0 A;  3EDG A;  1A85 A;  1A86 A;  1HY7 A;  1XAX A;  3P24 A;  4H2E A;  2DW1 A;  2V4B A;  2OXU A;  1PWP A;  3O64 A;  1HV5 A;  1MMB A;  2XS4 A;  3ELM A;  1TVI A;  1XFY A;  4GR3 A;  5BOT A;  2D1O A;  3G5C A;  3E8R A;  1CAQ A;  2OXW A;  1H71 P;  2SRT A;  1HFC A;  3LKA A;  1DMT A;  2O3E A;  4GWM A;  3KME A;  1KUK A;  4J4M A;  4DPE A;  4PKS A;  1HOV A;  4XM7 A;  1IAD A;  2O36 A;  4AXQ A;  1QJI A;  1O0T A;  1QIB A;  2JNP A;  2X3C A;  5D1S A;  5D1T A;  3KWV C;  3U1R A;  1K7I A;  2MLR A;  3DTI A;  1BKC E;  3EDI A;  1GKD A;  4CTH A;  4A3W A;  1RMZ A;  456C A;  4EFS A;  1ZVX A;  2DDY A;  3TS4 A;  1R1I A;  1XUD A;  4QKZ A;  1BUD A;  1R1J A;  1S4B P;  2A8H A;  1B8Y A;  1ATL A;  2OY2 A;  1XFW A;  2DDF A;  1MMR A;  1FM1 A;  1CK7 A;  1Y0V A;  1B3D A;  2WO8 A;  1EAK A;  1GO8 P;  1KAP P;  3EHY A;  3LEA A;  4H82 A;  3KEC A;  2WO9 A;  1Q3A A;  3K7L A;  2RJP A;  1K7Q A;  4PKW A;  3LIL A;  2CLT A;  1UEA A;  2CKI A;  1I73 A;  3WV3 A;  4GR8 A;  1XFZ A;  4XM6 A;  3EWJ A;  2DW0 A;  3F1A A;  1IAE A;  2E3X A;  1R1H A;  3I7I A;  2OI0 A;  1EB6 A;  2USN A;  3RTT A;  1IAA A;  3TT4 A;  1Z3J A;  2OZR A;  1I1I P;  2D1N A;  1R54 A;  3RTS A;  4I03 A;  2TCL A;  1XUR A;  2L0R A;  3KEK A;  4AIG A;  1OS2 A;  1RM8 A;  5I43 A;  3F15 A;  4IN9 A;  1D8M A;  3LJG A;  1WNI A;  1J7N A;  3HDA P;  4WKE A;  1IAC A;  4DF9 A;  4I35 A;  2N8R A;  1QIC A;  2OW2 A;  1BSW A;  1JAN A;  1MMQ A;  3KRY A;  5H8X A;  1G4K A;  4WK7 A;  4DV8 A;  1IAB A;  1YOU A;  3LJT A;  2OVZ A;  1D5J A;  1ZXC A;  3F17 A;  1SMP A;  3DPF A;  1OS9 A;  1BIW A;  2W0D A;  1HTD A;  2AIG P;  2OW1 A;  3B92 A;  4JQG A;  2MZI A;  3SHI A;  1JAQ A;  4WZV A;  2MZE A;  3AYU A;  2OXZ A;  4L63 A;  3N2V A;  4WKI A;  4L19 A;  5JMY A;  4IUW A;  3TSK A;  1ZTQ A;  3F19 A;  2W15 A;  5D3C A;  1JIZ A;  1SU3 A;  2AYK A; 
#chains in the Genus database with same CATH homology
 3WV2 A;  1CGL A;  4FXY P;  3EDZ A;  3VTG A;  4FU4 A;  3ZUK A;  2ERO A;  1UMT A;  2POJ A;  1EUB A;  1BZS A;  2OW0 A;  1ROS A;  1R55 A;  4PKR A;  3WV1 A;  1OM6 A;  3DL1 A;  1PWW A;  4H3X A;  3MA2 A;  1KUI A;  5B5O A;  3VI1 A;  1JJ9 A;  2QPJ A;  2Y6C A;  1SAT A;  1D7X A;  3BA0 A;  4WF6 A;  3DSL A;  4ZR5 A;  4A7B A;  1GE6 A;  1JKY A;  3DNG A;  3LUM A;  1OMJ A;  1CIZ A;  1YCM A;  1BM6 A;  4AUO A;  1UTZ A;  1AYK A;  3Q2G A;  3TVC A;  2J83 A;  2YUF A;  1PWV A;  1IAG A;  3F16 A;  2ERP A;  4XBH A;  3KHI A;  1JK3 A;  4PKV A;  2FV9 A;  2K9C A;  2ERQ A;  1C8T A;  1XUC A;  4HX3 A;  1D8F A;  3LE9 A;  1XFU A;  3EHX A;  2W13 A;  4XM8 A;  4G0D A;  1Y8J A;  2OVX A;  1QIA A;  4GUY A;  1USN A;  4GR0 A;  1C3I A;  2RJQ A;  1BQQ M;  1JH1 A;  3HYG A;  2Y6D A;  1G12 A;  3B2Z A;  3DPE A;  1UTT A;  4ON1 A;  1CQR A;  4R3V A;  5I2Z A;  1QUA A;  3LJZ A;  3KEJ A;  1BKC A;  3LMC A;  1G05 A;  4FXQ A;  1AF0 A;  3HY9 A;  4JPA A;  966C A;  4XCT A;  1JIW P;  3B8Z A;  1BUV M;  1L6J A;  3LK8 A;  4H30 A;  1XFX A;  1G49 A;  1OM7 A;  3N2U A;  2DW2 A;  2HU6 A;  3LQ0 A;  1JAP A;  3CKI A;  3L0T A;  4JIJ A;  3LIR A;  4JP4 A;  3ZXH A;  4H1Q A;  1SLN A;  4JA1 A;  2I47 A;  1GE5 A;  1GKC A;  4G9L A;  3K7N A;  5CZM A;  1CGE A;  3HBV P;  2W14 A;  3GBO A;  5I12 A;  2K2G A;  1BQO A;  4GWN A;  1FBL A;  2YB9 A;  3O2X A;  5LAB A;  2JT6 A;  5D7W A;  5L79 A;  2JT5 A;  2E2D A;  4AYK A;  1PWQ A;  3P1V A;  5L7F A;  1YQY A;  4L6T A;  3G42 A;  2X7M A;  2XS3 A;  3HY7 A;  4ILW D;  3V96 B;  3I7G A;  3HB2 P;  2X3B A;  2YIG A;  1UMS A;  1ZXV A;  3F18 A;  3DTE A;  5B5P A;  1GE7 A;  1OO9 A;  3AIG A;  4IJO A;  4H84 A;  1JAO A;  1FLS A;  3LQB A;  1CGF A;  4H49 A;  2FV5 A;  3UVC A;  5D1U A;  1CXV A;  2WOA A;  5I4O A;  1Y93 A;  2PJT A;  3AYK A;  1KUF A;  1GO7 P;  4HMA A;  1KUH A;  1ZP5 A;  1AKL A;  3LUN A;  3USN A;  1YP1 A;  4FVL A;  4L7A A;  4DD8 A;  4GF1 A;  3LIK A;  2Z2D A;  1O0Q A;  3HBU P;  3DWB A;  3KMC A;  4PKU A;  1XFV A;  1PWU A;  1SRP A;  2KRJ A;  5BOY A;  5I0L A;  3L0V A;  2OW9 A;  2X3A A;  4PKQ A;  1SLM A;  2J0T A;  4PKT A;  5I3M A;  1DTH A;  3LGP A;  2MLS A;  5CUH A;  2W12 A;  1K7G A;  1MMP A;  1I76 A;  5CXA A;  5D2B A;  3ZVS A;  2OY4 A;  2JSD A;  1AST A;  1KUG A;  1C7K A;  1QJJ A;  3DTK A;  1ND1 A;  1BKC I;  1MNC A;  2MZH A;  3EDH A;  830C A;  1KBC A;  5BPA A;  1GXD A;  1OM8 A;  3Q2H A;  1G9K A;  2JIH A;  3OHL A;  3OHO A;  4H76 A;  4GQL A;  3HDB A;  3NX7 A;  1HFS A;  4Q1L A;  1ZS0 A;  3EDG A;  1A85 A;  1A86 A;  1HY7 A;  3P24 A;  4H2E A;  2DW1 A;  2V4B A;  2OXU A;  1PWP A;  3O64 A;  1HV5 A;  1MMB A;  2XS4 A;  3ELM A;  1XFY A;  4GR3 A;  5BOT A;  2D1O A;  3G5C A;  3E8R A;  1CAQ A;  2OXW A;  1H71 P;  2SRT A;  1HFC A;  3LKA A;  1DMT A;  2O3E A;  4GWM A;  3KME A;  1KUK A;  4J4M A;  4DPE A;  4PKS A;  1HOV A;  4XM7 A;  1IAD A;  2O36 A;  4AXQ A;  1QJI A;  1O0T A;  1QIB A;  2JNP A;  2X3C A;  5D1S A;  5D1T A;  3KWV C;  3U1R A;  1K7I A;  2MLR A;  3DTI A;  1BKC E;  3EDI A;  1GKD A;  4CTH A;  4A3W A;  1RMZ A;  456C A;  4EFS A;  1ZVX A;  2DDY A;  3TS4 A;  1R1I A;  1XUD A;  4QKZ A;  1BUD A;  1R1J A;  1S4B P;  2A8H A;  1B8Y A;  1ATL A;  2OY2 A;  1XFW A;  2DDF A;  1MMR A;  1FM1 A;  1CK7 A;  1Y0V A;  1B3D A;  2WO8 A;  1EAK A;  1GO8 P;  1KAP P;  3EHY A;  3LEA A;  4H82 A;  3KEC A;  2WO9 A;  1Q3A A;  3K7L A;  2RJP A;  1K7Q A;  4PKW A;  3LIL A;  2CLT A;  1UEA A;  2CKI A;  1I73 A;  3WV3 A;  4GR8 A;  1XFZ A;  4XM6 A;  3EWJ A;  2DW0 A;  3F1A A;  1IAE A;  2E3X A;  1R1H A;  3I7I A;  2OI0 A;  1EB6 A;  2USN A;  3RTT A;  1IAA A;  3TT4 A;  1Z3J A;  2OZR A;  1I1I P;  2D1N A;  1R54 A;  3RTS A;  4I03 A;  2TCL A;  1XUR A;  2L0R A;  3KEK A;  4AIG A;  1OS2 A;  1RM8 A;  5I43 A;  3F15 A;  4IN9 A;  1D8M A;  3LJG A;  1WNI A;  1J7N A;  3HDA P;  4WKE A;  1IAC A;  4DF9 A;  4I35 A;  2N8R A;  1QIC A;  2OW2 A;  1BSW A;  1JAN A;  1MMQ A;  3KRY A;  5H8X A;  1G4K A;  4WK7 A;  4DV8 A;  1IAB A;  1YOU A;  3LJT A;  2OVZ A;  1D5J A;  1ZXC A;  3F17 A;  1SMP A;  3DPF A;  1OS9 A;  1BIW A;  2W0D A;  1HTD A;  2AIG P;  2OW1 A;  3B92 A;  4JQG A;  2MZI A;  3SHI A;  1JAQ A;  4WZV A;  2MZE A;  3AYU A;  2OXZ A;  4L63 A;  3N2V A;  4WKI A;  4L19 A;  5JMY A;  4IUW A;  3TSK A;  1ZTQ A;  3F19 A;  2W15 A;  5D3C A;  1JIZ A;  1SU3 A;  2AYK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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