3HYGA

Crystal structure of the catalytic domain of adamts-5 in complex with an amino-2-indanol compound
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
217
structure length
217
Chain Sequence
SRARQVELLLVADASMARKYGRGLQHYLLTLASIANRLYSHASIENHIRLAVVKVVVLGDKDKSLEVSKNAATTLKNFCKWQHQHNQLGDDHEEHYDAAILFTREDLCGHHSCDTLGMADVGTICSPERSCAVIEDDGLHAAFTVAHEIGHLLGLSHDDSKFCEETFGSTEDKRLMSSILTSIDASKPWSKCTSATITEFLDDGHGNCLLDLPRKQI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural and inhibition analysis reveals the mechanism of selectivity of a series of aggrecanase inhibitors
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords A disintegrin and metalloproteinase with thrombospondin moti
total genus 73
structure length 217
sequence length 217
chains with identical sequence B
ec nomenclature ec 3.4.24.-:
pdb deposition date 2009-06-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01421 Reprolysin Reprolysin (M12B) family zinc metalloprotease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3hygA00
1OM8A 2MLSA 2FV9A 1BSWA 1G12A 5D1UA 1UMTA 3LIKA 4DV8A 4QKZA 4IUWA 3HYGA 1JK3A 1HY7A 1ATLA 1L6JA 1UMSA 2WO9A 1XFXA 3WV2A 1HFCA 4PKQA 4XBHA 5D1SA 3O2XA 2W0DA 3LQBA 2USNA 2Z2DA 1CGFA 1Z3JA 4ZR5A 1K7GA 3HBUP 1USNA 2EROA 2XS4A 1QICA 5JMYA 2OXUA 4GR8A 5LABA 1MNCA 1ZVXA 2I47A 1ZP5A 4XM8A 3RTSA 3HY7A 3F18A 4WK7A 1BIWA 1YP1A 1PWPA 3KRYA 4H84A 1ZXCA 5D7WA 1SLMA 1CAQA 3Q2GA 3L0TA 3Q2HA 1FM1A 1HOVA 4G9LA 2W13A 3LJGA 2JT6A 4H3XA 1GE7A 2AYKA 3G5CA 2D1NA 2WOAA 1QUAA 4EFSA 1JIZA 1K7IA 3TSKA 3LK8A 3ZVSA 3ZXHA 1MMBA 1D8MA 2OXZA 1IAGA 1D8FA 1GKCA 2DDYA 1I76A 3EDIA 4L19A 3USNA 3TS4A 3GBOA 2YB9A 1WNIA 5D2BA 1OMJA 1EUBA 3G42A 4GUYA 1KAPP 1OO9A 3MA2A 2K2GA 3AYUA 4FXQA 4JIJA 1O0QA 3UVCA 1C3IA 2OVXA 2DW2A 2OW1A 5BOTA 1G49A 3AYKA 3DWBA 1JAQA 1XFVA 3TT4A 4GR3A 1R1HA 2E2DA 5L7FA 1AKLA 3VI1A 1JJ9A 2CLTA 1XFZA 1PWWA 2CKIA 1IACA 1AYKA 3LGPA 1C7KA 4WF6A 1EB6A 4JP4A 4A7BA 1ASTA 1UEAA 2KRJA 4L6TA 1Y93A 1AF0A 1Y8JA 3HDAP 4H2EA 1ROSA 2DW0A 1I1IP 2MZEA 3K7NA 3SHIA 2OI0A 3F16A 3VTGA 5BOYA 3DNGA 1MMRA 2PJTA 4I35A 3TVCA 1RMZA 4XM7A 4WZVA 1XURA 1GE6A 2HU6A 4GWMA 2K9CA 4CTHA 5D3CA 1R1JA 1B3DA 3LUNA 2D1OA 2JSDA 2DDFA 1SLNA 1GE5A 1R1IA 3V96B 4ILWD 4L63A 1XUCA 3KHIA 4WKIA 2N8RA 3I7GA 5CUHA 1SATA 2O36A 2Y6CA 4DPEA 4AUOA 830CA 1XFWA 2AIGP 4GWNA 3I7IA 1JANA 1HTDA 4R3VA 3F15A 3DPEA 4ON1A 4DF9A 5I2ZA 1D5JA 3B8ZA 1OM6A 1QIAA 5I3MA 2OY2A 3L0VA 1O0TA 2RJQA 1QIBA 2A8HA 2MZHA 2OXWA 3EHXA 3EWJA 4HX3A 3O64A 1DTHA 1JH1A 1ND1A 4FU4A 4G0DA 4AIGA 4PKUA 2X7MA 1OS2A 1FLSA 1G05A 2SRTA 2JNPA 4Q1LA 1YQYA 3CKIA 1YCMA 3K7LA 1GXDA 4IN9A 1UTZA 2OW0A 3KEJA 4GF1A 1A86A 1BKCE 1R55A 1BKCI 4H1QA 2RJPA 1Y0VA 5I4OA 1J7NA 1SU3A 2WO8A 1IABA 5I12A 1SRPA 1IAAA 1CGEA 1BUVM 2Y6DA 3U1RA 4J4MA 1K7QA 3WV1A 1BM6A 2MZIA 3F1AA 5H8XA 1QJIA 3KMEA 2OVZA 3HY9A 1DMTA 2W12A 4H82A 3LMCA 2V4BA 1Q3AA 1KUIA 1KBCA 1KUFA 3KECA 2DW1A 4JQGA 3P24A 3KMCA 1JKYA 3B92A 1RM8A 5L79A 1G4KA 3LQ0A 3WV3A 3AIGA 3LEAA 2L0RA 1CXVA 3LUMA 3KEKA 456CA 1OM7A 1KUHA 1JAPA 1SMPA 2FV5A 2ERQA 1D7XA 3HBVP 1CIZA 2POJA 3F17A 4AYKA 3P1VA 3DSLA 1MMPA 4WKEA 5D1TA 4PKRA 2ERPA 4PKWA 1CQRA 1KUKA 2W14A 2E3XA 1BZSA 4IJOA 1BQQM 2OW9A 3HDBA 2J83A 3DL1A 2OW2A 3N2UA 4XCTA 3EDHA 1S4BP 3OHOA 2YIGA 3EHYA 2OZRA 2JT5A 966CA 3HB2P 3E8RA 4H76A 1IADA 2MLRA 3EDGA 4JPAA 2X3CA 4PKSA 3BA0A 3RTTA 1IAEA 3NX7A 2XS3A 1H71P 3LE9A 2QPJA 3B2ZA 1HFSA 1CGLA 1ZTQA 4FVLA 1ZS0A 1R54A 1FBLA 1CK7A 1KUGA 3KWVC 4JA1A 1B8YA 1GKDA 5I43A 1C8TA 4AXQA 1GO7P 3EDZA 3F19A 1EAKA 4PKTA 5B5PA 4A3WA 3LJTA 1OS9A 1MMQA 4H30A 2JIHA 3LKAA 5BPAA 4DD8A 3N2VA 2X3BA 3LIRA 5B5OA 1YOUA 4I03A 2O3EA 1UTTA 3LILA 3OHLA 2X3AA 2W15A 4H49A 3ELMA 4PKVA 1GO8P 1PWVA 5I0LA 1QJJA 1JIWP 3ZUKA 1JAOA 1PWUA 1XFYA 3DPFA 1XFUA 4FXYP 3LJZA 5CZMA 1A85A 1BUDA 4GR0A 4HMAA 2OY4A 2TCLA 2J0TA 1G9KA 4XM6A 1I73A 1BQOA 1PWQA 4GQLA 5CXAA 1XUDA 1HV5A 1ZXVA 1BKCA
chains in the Genus database with same CATH superfamily
1OM8A 2MLSA 2FV9A 1BSWA 1G12A 5D1UA 1UMTA 3LIKA 4DV8A 4QKZA 4IUWA 1TVIA 3HYGA 1JK3A 2YUFA 1HY7A 1ATLA 1L6JA 1UMSA 2WO9A 1XFXA 3WV2A 1HFCA 4PKQA 4XBHA 5D1SA 3O2XA 2W0DA 3LQBA 2USNA 2Z2DA 1CGFA 1Z3JA 4ZR5A 1K7GA 3HBUP 1USNA 2EROA 2XS4A 1QICA 5JMYA 2OXUA 4GR8A 5LABA 1MNCA 1ZVXA 2I47A 1ZP5A 4XM8A 3RTSA 3HY7A 3F18A 4WK7A 1BIWA 1YP1A 1PWPA 3DTIA 3KRYA 4H84A 1ZXCA 5D7WA 1SLMA 1CAQA 3Q2GA 3L0TA 3Q2HA 1FM1A 1HOVA 4G9LA 2W13A 3LJGA 2JT6A 4H3XA 1GE7A 2AYKA 3G5CA 2D1NA 2WOAA 1QUAA 4EFSA 1JIZA 1K7IA 3TSKA 3LK8A 3ZVSA 3ZXHA 1MMBA 1D8MA 2OXZA 1IAGA 1D8FA 1GKCA 2DDYA 1I76A 3EDIA 4L19A 3USNA 1OZ9A 3TS4A 3GBOA 2YB9A 1WNIA 5D2BA 1OMJA 1EUBA 3G42A 4GUYA 1KAPP 1OO9A 3MA2A 2K2GA 3AYUA 4FXQA 4JIJA 1O0QA 3UVCA 1C3IA 2OVXA 2DW2A 2OW1A 5BOTA 1G49A 3AYKA 3DWBA 1JAQA 1XFVA 3TT4A 4GR3A 1R1HA 2E2DA 5L7FA 1AKLA 3VI1A 1JJ9A 2CLTA 1XFZA 1PWWA 2CKIA 1IACA 1AYKA 3LGPA 1C7KA 4WF6A 1EB6A 4JP4A 4A7BA 1ASTA 1UEAA 2KRJA 4L6TA 1Y93A 1AF0A 1Y8JA 3HDAP 1XAXA 4H2EA 1ROSA 2DW0A 1I1IP 2MZEA 3K7NA 3SHIA 2OI0A 3F16A 3VTGA 5BOYA 3DNGA 1MMRA 2PJTA 4I35A 3TVCA 1RMZA 4XM7A 4WZVA 1XURA 1GE6A 2HU6A 4GWMA 2K9CA 4CTHA 5D3CA 1R1JA 1B3DA 3LUNA 2D1OA 2JSDA 2DDFA 1SLNA 1GE5A 1R1IA 3V96B 4ILWD 4L63A 1XUCA 3KHIA 4WKIA 2N8RA 3I7GA 5CUHA 1SATA 2O36A 2Y6CA 4DPEA 4AUOA 830CA 1XFWA 2AIGP 4GWNA 3I7IA 1JANA 1HTDA 4R3VA 3F15A 3DPEA 4ON1A 4DF9A 5I2ZA 1D5JA 3B8ZA 1OM6A 1QIAA 5I3MA 2OY2A 3L0VA 1O0TA 2RJQA 1QIBA 2A8HA 2MZHA 2OXWA 3EHXA 3EWJA 4HX3A 3O64A 1DTHA 1JH1A 1ND1A 4FU4A 4G0DA 4AIGA 4PKUA 2X7MA 1OS2A 1FLSA 1G05A 2SRTA 2JNPA 4Q1LA 1YQYA 3CKIA 1YCMA 3K7LA 1GXDA 4IN9A 1UTZA 2OW0A 3KEJA 4GF1A 1A86A 1BKCE 1R55A 1BKCI 4H1QA 2RJPA 1Y0VA 5I4OA 1J7NA 1SU3A 2WO8A 1IABA 5I12A 1SRPA 1IAAA 1CGEA 1BUVM 2Y6DA 3U1RA 4J4MA 1K7QA 3WV1A 1BM6A 2MZIA 3F1AA 5H8XA 1QJIA 3KMEA 2OVZA 3HY9A 1DMTA 2W12A 4H82A 3LMCA 4L7AA 2V4BA 1Q3AA 1KUIA 1KBCA 1KUFA 3KECA 2DW1A 4JQGA 3P24A 3KMCA 1JKYA 3B92A 1RM8A 5L79A 1G4KA 3LQ0A 3WV3A 3AIGA 3LEAA 2L0RA 1CXVA 3LUMA 3KEKA 456CA 1OM7A 1KUHA 1JAPA 1SMPA 2FV5A 2ERQA 1D7XA 3HBVP 1CIZA 2POJA 3F17A 4AYKA 3P1VA 3DTEA 3DSLA 1MMPA 4WKEA 3DTKA 5D1TA 4PKRA 2ERPA 4PKWA 1CQRA 1KUKA 2W14A 2E3XA 1BZSA 4IJOA 1BQQM 2OW9A 3HDBA 2J83A 3DL1A 2OW2A 3N2UA 4XCTA 3EDHA 1S4BP 3OHOA 2YIGA 3EHYA 2OZRA 2JT5A 966CA 3HB2P 3E8RA 4H76A 1IADA 2MLRA 3EDGA 4JPAA 2X3CA 4PKSA 3BA0A 3RTTA 1IAEA 3NX7A 2XS3A 1XM5A 1H71P 3LE9A 2QPJA 3B2ZA 1HFSA 1CGLA 1ZTQA 4FVLA 1ZS0A 1R54A 1FBLA 1CK7A 1KUGA 3KWVC 4JA1A 1B8YA 1GKDA 5I43A 1C8TA 4AXQA 1GO7P 3EDZA 3F19A 1EAKA 4PKTA 5B5PA 4A3WA 3LJTA 1OS9A 1MMQA 4H30A 2JIHA 3LKAA 5BPAA 4DD8A 3N2VA 2X3BA 3LIRA 5B5OA 1YOUA 4I03A 2O3EA 1UTTA 3LILA 3OHLA 2X3AA 2W15A 4H49A 3ELMA 4PKVA 1GO8P 1PWVA 5I0LA 1QJJA 1JIWP 3ZUKA 1JAOA 1PWUA 1XFYA 3DPFA 1XFUA 4FXYP 3LJZA 5CZMA 1A85A 1BUDA 4GR0A 4HMAA 2OY4A 2TCLA 2J0TA 1G9KA 4XM6A 1I73A 1BQOA 1PWQA 4GQLA 5CXAA 1XUDA 1HV5A 1ZXVA 1BKCA
chains in the Genus database with same CATH topology
1OM8A 2MLSA 2FV9A 1BSWA 1G12A 5D1UA 1UMTA 3LIKA 4DV8A 4QKZA 4IUWA 3HYGA 1JK3A 2YUFA 1HY7A 1ATLA 1L6JA 1UMSA 2WO9A 1XFXA 3WV2A 1HFCA 4PKQA 4XBHA 5D1SA 3O2XA 2W0DA 3LQBA 2USNA 2Z2DA 1CGFA 1Z3JA 4ZR5A 1K7GA 3HBUP 1USNA 2EROA 2XS4A 1QICA 5JMYA 2OXUA 4GR8A 5LABA 1MNCA 1ZVXA 2I47A 1ZP5A 4XM8A 3RTSA 3HY7A 3F18A 4WK7A 1BIWA 1YP1A 1PWPA 3DTIA 3KRYA 4H84A 1ZXCA 5D7WA 1SLMA 1CAQA 3Q2GA 3L0TA 3Q2HA 1FM1A 1HOVA 4G9LA 2W13A 3LJGA 2JT6A 4H3XA 1GE7A 2AYKA 3G5CA 2D1NA 2WOAA 1QUAA 4EFSA 1JIZA 1K7IA 3TSKA 3LK8A 3ZVSA 3ZXHA 1MMBA 1D8MA 2OXZA 1IAGA 1D8FA 1GKCA 2DDYA 1I76A 3EDIA 4L19A 3USNA 3TS4A 3GBOA 2YB9A 1WNIA 5D2BA 1OMJA 1EUBA 3G42A 4GUYA 1KAPP 1OO9A 3MA2A 2K2GA 3AYUA 4FXQA 4JIJA 1O0QA 3UVCA 1C3IA 2OVXA 2DW2A 2OW1A 5BOTA 1G49A 3AYKA 3DWBA 1JAQA 1XFVA 3TT4A 4GR3A 1R1HA 2E2DA 5L7FA 1AKLA 3VI1A 1JJ9A 2CLTA 1XFZA 1PWWA 2CKIA 1IACA 1AYKA 3LGPA 1C7KA 4WF6A 1EB6A 4JP4A 4A7BA 1ASTA 1UEAA 2KRJA 4L6TA 1Y93A 1AF0A 1Y8JA 3HDAP 4H2EA 1ROSA 2DW0A 1I1IP 2MZEA 3K7NA 3SHIA 2OI0A 3F16A 3VTGA 5BOYA 3DNGA 1MMRA 2PJTA 4I35A 3TVCA 1RMZA 4XM7A 4WZVA 1XURA 1GE6A 2HU6A 4GWMA 2K9CA 4CTHA 5D3CA 1R1JA 1B3DA 3LUNA 2D1OA 2JSDA 2DDFA 1SLNA 1GE5A 1R1IA 3V96B 4ILWD 4L63A 1XUCA 3KHIA 4WKIA 2N8RA 3I7GA 5CUHA 1SATA 2O36A 2Y6CA 4DPEA 4AUOA 830CA 1XFWA 2AIGP 4GWNA 3I7IA 1JANA 1HTDA 4R3VA 3F15A 3DPEA 4ON1A 4DF9A 5I2ZA 1D5JA 3B8ZA 1OM6A 1QIAA 5I3MA 2OY2A 3L0VA 1O0TA 2RJQA 1QIBA 2A8HA 2MZHA 2OXWA 3EHXA 3EWJA 4HX3A 3O64A 1DTHA 1JH1A 1ND1A 4FU4A 4G0DA 4AIGA 4PKUA 2X7MA 1OS2A 1FLSA 1G05A 2SRTA 2JNPA 4Q1LA 1YQYA 3CKIA 1YCMA 3K7LA 1GXDA 4IN9A 1UTZA 2OW0A 3KEJA 4GF1A 1A86A 1BKCE 1R55A 1BKCI 4H1QA 2RJPA 1Y0VA 5I4OA 1J7NA 1SU3A 2WO8A 1IABA 5I12A 1SRPA 1IAAA 1CGEA 1BUVM 2Y6DA 3U1RA 4J4MA 1K7QA 3WV1A 1BM6A 2MZIA 3F1AA 5H8XA 1QJIA 3KMEA 2OVZA 3HY9A 1DMTA 2W12A 4H82A 3LMCA 4L7AA 2V4BA 1Q3AA 1KUIA 1KBCA 1KUFA 3KECA 2DW1A 4JQGA 3P24A 3KMCA 1JKYA 3B92A 1RM8A 5L79A 1G4KA 3LQ0A 3WV3A 3AIGA 3LEAA 2L0RA 1CXVA 3LUMA 3KEKA 456CA 1OM7A 1KUHA 1JAPA 1SMPA 2FV5A 2ERQA 1D7XA 3HBVP 1CIZA 2POJA 3F17A 4AYKA 3P1VA 3DTEA 3DSLA 1MMPA 4WKEA 3DTKA 5D1TA 4PKRA 2ERPA 4PKWA 1CQRA 1KUKA 2W14A 2E3XA 1BZSA 4IJOA 1BQQM 2OW9A 3HDBA 2J83A 3DL1A 2OW2A 3N2UA 4XCTA 3EDHA 1S4BP 3OHOA 2YIGA 3EHYA 2OZRA 2JT5A 966CA 3HB2P 3E8RA 4H76A 1IADA 2MLRA 3EDGA 4JPAA 2X3CA 4PKSA 3BA0A 3RTTA 1IAEA 3NX7A 2XS3A 1H71P 3LE9A 2QPJA 3B2ZA 1HFSA 1CGLA 1ZTQA 4FVLA 1ZS0A 1R54A 1FBLA 1CK7A 1KUGA 3KWVC 4JA1A 1B8YA 1GKDA 5I43A 1C8TA 4AXQA 1GO7P 3EDZA 3F19A 1EAKA 4PKTA 5B5PA 4A3WA 3LJTA 1OS9A 1MMQA 4H30A 2JIHA 3LKAA 5BPAA 4DD8A 3N2VA 2X3BA 3LIRA 5B5OA 1YOUA 4I03A 2O3EA 1UTTA 3LILA 3OHLA 2X3AA 2W15A 4H49A 3ELMA 4PKVA 1GO8P 1PWVA 5I0LA 1QJJA 1JIWP 3ZUKA 1JAOA 1PWUA 1XFYA 3DPFA 1XFUA 4FXYP 3LJZA 5CZMA 1A85A 1BUDA 4GR0A 4HMAA 2OY4A 2TCLA 2J0TA 1G9KA 4XM6A 1I73A 1BQOA 1PWQA 4GQLA 5CXAA 1XUDA 1HV5A 1ZXVA 1BKCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OM8 A;  2MLS A;  2FV9 A;  1BSW A;  1G12 A;  5D1U A;  1UMT A;  3LIK A;  4DV8 A;  4QKZ A;  4IUW A;  3HYG A;  1JK3 A;  1HY7 A;  1ATL A;  1L6J A;  1UMS A;  2WO9 A;  1XFX A;  3WV2 A;  1HFC A;  4PKQ A;  4XBH A;  5D1S A;  3O2X A;  2W0D A;  3LQB A;  2USN A;  2Z2D A;  1CGF A;  1Z3J A;  4ZR5 A;  1K7G A;  3HBU P;  1USN A;  2ERO A;  2XS4 A;  1QIC A;  5JMY A;  2OXU A;  4GR8 A;  5LAB A;  1MNC A;  1ZVX A;  2I47 A;  1ZP5 A;  4XM8 A;  3RTS A;  3HY7 A;  3F18 A;  4WK7 A;  1BIW A;  1YP1 A;  1PWP A;  3KRY A;  4H84 A;  1ZXC A;  5D7W A;  1SLM A;  1CAQ A;  3Q2G A;  3L0T A;  3Q2H A;  1FM1 A;  1HOV A;  4G9L A;  2W13 A;  3LJG A;  2JT6 A;  4H3X A;  1GE7 A;  2AYK A;  3G5C A;  2D1N A;  2WOA A;  1QUA A;  4EFS A;  1JIZ A;  1K7I A;  3TSK A;  3LK8 A;  3ZVS A;  3ZXH A;  1MMB A;  1D8M A;  2OXZ A;  1IAG A;  1D8F A;  1GKC A;  2DDY A;  1I76 A;  3EDI A;  4L19 A;  3USN A;  3TS4 A;  3GBO A;  2YB9 A;  1WNI A;  5D2B A;  1OMJ A;  1EUB A;  3G42 A;  4GUY A;  1KAP P;  1OO9 A;  3MA2 A;  2K2G A;  3AYU A;  4FXQ A;  4JIJ A;  1O0Q A;  3UVC A;  1C3I A;  2OVX A;  2DW2 A;  2OW1 A;  5BOT A;  1G49 A;  3AYK A;  3DWB A;  1JAQ A;  1XFV A;  3TT4 A;  4GR3 A;  1R1H A;  2E2D A;  5L7F A;  1AKL A;  3VI1 A;  1JJ9 A;  2CLT A;  1XFZ A;  1PWW A;  2CKI A;  1IAC A;  1AYK A;  3LGP A;  1C7K A;  4WF6 A;  1EB6 A;  4JP4 A;  4A7B A;  1AST A;  1UEA A;  2KRJ A;  4L6T A;  1Y93 A;  1AF0 A;  1Y8J A;  3HDA P;  4H2E A;  1ROS A;  2DW0 A;  1I1I P;  2MZE A;  3K7N A;  3SHI A;  2OI0 A;  3F16 A;  3VTG A;  5BOY A;  3DNG A;  1MMR A;  2PJT A;  4I35 A;  3TVC A;  1RMZ A;  4XM7 A;  4WZV A;  1XUR A;  1GE6 A;  2HU6 A;  4GWM A;  2K9C A;  4CTH A;  5D3C A;  1R1J A;  1B3D A;  3LUN A;  2D1O A;  2JSD A;  2DDF A;  1SLN A;  1GE5 A;  1R1I A;  3V96 B;  4ILW D;  4L63 A;  1XUC A;  3KHI A;  4WKI A;  2N8R A;  3I7G A;  5CUH A;  1SAT A;  2O36 A;  2Y6C A;  4DPE A;  4AUO A;  830C A;  1XFW A;  2AIG P;  4GWN A;  3I7I A;  1JAN A;  1HTD A;  4R3V A;  3F15 A;  3DPE A;  4ON1 A;  4DF9 A;  5I2Z A;  1D5J A;  3B8Z A;  1OM6 A;  1QIA A;  5I3M A;  2OY2 A;  3L0V A;  1O0T A;  2RJQ A;  1QIB A;  2A8H A;  2MZH A;  2OXW A;  3EHX A;  3EWJ A;  4HX3 A;  3O64 A;  1DTH A;  1JH1 A;  1ND1 A;  4FU4 A;  4G0D A;  4AIG A;  4PKU A;  2X7M A;  1OS2 A;  1FLS A;  1G05 A;  2SRT A;  2JNP A;  4Q1L A;  1YQY A;  3CKI A;  1YCM A;  3K7L A;  1GXD A;  4IN9 A;  1UTZ A;  2OW0 A;  3KEJ A;  4GF1 A;  1A86 A;  1BKC E;  1R55 A;  1BKC I;  4H1Q A;  2RJP A;  1Y0V A;  5I4O A;  1J7N A;  1SU3 A;  2WO8 A;  1IAB A;  5I12 A;  1SRP A;  1IAA A;  1CGE A;  1BUV M;  2Y6D A;  3U1R A;  4J4M A;  1K7Q A;  3WV1 A;  1BM6 A;  2MZI A;  3F1A A;  5H8X A;  1QJI A;  3KME A;  2OVZ A;  3HY9 A;  1DMT A;  2W12 A;  4H82 A;  3LMC A;  2V4B A;  1Q3A A;  1KUI A;  1KBC A;  1KUF A;  3KEC A;  2DW1 A;  4JQG A;  3P24 A;  3KMC A;  1JKY A;  3B92 A;  1RM8 A;  5L79 A;  1G4K A;  3LQ0 A;  3WV3 A;  3AIG A;  3LEA A;  2L0R A;  1CXV A;  3LUM A;  3KEK A;  456C A;  1OM7 A;  1KUH A;  1JAP A;  1SMP A;  2FV5 A;  2ERQ A;  1D7X A;  3HBV P;  1CIZ A;  2POJ A;  3F17 A;  4AYK A;  3P1V A;  3DSL A;  1MMP A;  4WKE A;  5D1T A;  4PKR A;  2ERP A;  4PKW A;  1CQR A;  1KUK A;  2W14 A;  2E3X A;  1BZS A;  4IJO A;  1BQQ M;  2OW9 A;  3HDB A;  2J83 A;  3DL1 A;  2OW2 A;  3N2U A;  4XCT A;  3EDH A;  1S4B P;  3OHO A;  2YIG A;  3EHY A;  2OZR A;  2JT5 A;  966C A;  3HB2 P;  3E8R A;  4H76 A;  1IAD A;  2MLR A;  3EDG A;  4JPA A;  2X3C A;  4PKS A;  3BA0 A;  3RTT A;  1IAE A;  3NX7 A;  2XS3 A;  1H71 P;  3LE9 A;  2QPJ A;  3B2Z A;  1HFS A;  1CGL A;  1ZTQ A;  4FVL A;  1ZS0 A;  1R54 A;  1FBL A;  1CK7 A;  1KUG A;  3KWV C;  4JA1 A;  1B8Y A;  1GKD A;  5I43 A;  1C8T A;  4AXQ A;  1GO7 P;  3EDZ A;  3F19 A;  1EAK A;  4PKT A;  5B5P A;  4A3W A;  3LJT A;  1OS9 A;  1MMQ A;  4H30 A;  2JIH A;  3LKA A;  5BPA A;  4DD8 A;  3N2V A;  2X3B A;  3LIR A;  5B5O A;  1YOU A;  4I03 A;  2O3E A;  1UTT A;  3LIL A;  3OHL A;  2X3A A;  2W15 A;  4H49 A;  3ELM A;  4PKV A;  1GO8 P;  1PWV A;  5I0L A;  1QJJ A;  1JIW P;  3ZUK A;  1JAO A;  1PWU A;  1XFY A;  3DPF A;  1XFU A;  4FXY P;  3LJZ A;  5CZM A;  1A85 A;  1BUD A;  4GR0 A;  4HMA A;  2OY4 A;  2TCL A;  2J0T A;  1G9K A;  4XM6 A;  1I73 A;  1BQO A;  1PWQ A;  4GQL A;  5CXA A;  1XUD A;  1HV5 A;  1ZXV A;  1BKC A; 
#chains in the Genus database with same CATH topology
 1OM8 A;  2MLS A;  2FV9 A;  1BSW A;  1G12 A;  5D1U A;  1UMT A;  3LIK A;  4DV8 A;  4QKZ A;  4IUW A;  1TVI A;  3HYG A;  1JK3 A;  2YUF A;  1HY7 A;  1ATL A;  1L6J A;  1UMS A;  2WO9 A;  1XFX A;  3WV2 A;  1HFC A;  4PKQ A;  4XBH A;  5D1S A;  3O2X A;  2W0D A;  3LQB A;  2USN A;  2Z2D A;  1CGF A;  1Z3J A;  4ZR5 A;  1K7G A;  3HBU P;  1USN A;  2ERO A;  2XS4 A;  1QIC A;  5JMY A;  2OXU A;  4GR8 A;  5LAB A;  1MNC A;  1ZVX A;  2I47 A;  1ZP5 A;  4XM8 A;  3RTS A;  3HY7 A;  3F18 A;  4WK7 A;  1BIW A;  1YP1 A;  1PWP A;  3DTI A;  3KRY A;  4H84 A;  1ZXC A;  5D7W A;  1SLM A;  1CAQ A;  3Q2G A;  3L0T A;  3Q2H A;  1FM1 A;  1HOV A;  4G9L A;  2W13 A;  3LJG A;  2JT6 A;  4H3X A;  1GE7 A;  2AYK A;  3G5C A;  2D1N A;  2WOA A;  1QUA A;  4EFS A;  1JIZ A;  1K7I A;  3TSK A;  3LK8 A;  3ZVS A;  3ZXH A;  1MMB A;  1D8M A;  2OXZ A;  1IAG A;  1D8F A;  1GKC A;  2DDY A;  1I76 A;  3EDI A;  4L19 A;  3USN A;  1OZ9 A;  3TS4 A;  3GBO A;  2YB9 A;  1WNI A;  5D2B A;  1OMJ A;  1EUB A;  3G42 A;  4GUY A;  1KAP P;  1OO9 A;  3MA2 A;  2K2G A;  3AYU A;  4FXQ A;  4JIJ A;  1O0Q A;  3UVC A;  1C3I A;  2OVX A;  2DW2 A;  2OW1 A;  5BOT A;  1G49 A;  3AYK A;  3DWB A;  1JAQ A;  1XFV A;  3TT4 A;  4GR3 A;  1R1H A;  2E2D A;  5L7F A;  1AKL A;  3VI1 A;  1JJ9 A;  2CLT A;  1XFZ A;  1PWW A;  2CKI A;  1IAC A;  1AYK A;  3LGP A;  1C7K A;  4WF6 A;  1EB6 A;  4JP4 A;  4A7B A;  1AST A;  1UEA A;  2KRJ A;  4L6T A;  1Y93 A;  1AF0 A;  1Y8J A;  3HDA P;  1XAX A;  4H2E A;  1ROS A;  2DW0 A;  1I1I P;  2MZE A;  3K7N A;  3SHI A;  2OI0 A;  3F16 A;  3VTG A;  5BOY A;  3DNG A;  1MMR A;  2PJT A;  4I35 A;  3TVC A;  1RMZ A;  4XM7 A;  4WZV A;  1XUR A;  1GE6 A;  2HU6 A;  4GWM A;  2K9C A;  4CTH A;  5D3C A;  1R1J A;  1B3D A;  3LUN A;  2D1O A;  2JSD A;  2DDF A;  1SLN A;  1GE5 A;  1R1I A;  3V96 B;  4ILW D;  4L63 A;  1XUC A;  3KHI A;  4WKI A;  2N8R A;  3I7G A;  5CUH A;  1SAT A;  2O36 A;  2Y6C A;  4DPE A;  4AUO A;  830C A;  1XFW A;  2AIG P;  4GWN A;  3I7I A;  1JAN A;  1HTD A;  4R3V A;  3F15 A;  3DPE A;  4ON1 A;  4DF9 A;  5I2Z A;  1D5J A;  3B8Z A;  1OM6 A;  1QIA A;  5I3M A;  2OY2 A;  3L0V A;  1O0T A;  2RJQ A;  1QIB A;  2A8H A;  2MZH A;  2OXW A;  3EHX A;  3EWJ A;  4HX3 A;  3O64 A;  1DTH A;  1JH1 A;  1ND1 A;  4FU4 A;  4G0D A;  4AIG A;  4PKU A;  2X7M A;  1OS2 A;  1FLS A;  1G05 A;  2SRT A;  2JNP A;  4Q1L A;  1YQY A;  3CKI A;  1YCM A;  3K7L A;  1GXD A;  4IN9 A;  1UTZ A;  2OW0 A;  3KEJ A;  4GF1 A;  1A86 A;  1BKC E;  1R55 A;  1BKC I;  4H1Q A;  2RJP A;  1Y0V A;  5I4O A;  1J7N A;  1SU3 A;  2WO8 A;  1IAB A;  5I12 A;  1SRP A;  1IAA A;  1CGE A;  1BUV M;  2Y6D A;  3U1R A;  4J4M A;  1K7Q A;  3WV1 A;  1BM6 A;  2MZI A;  3F1A A;  5H8X A;  1QJI A;  3KME A;  2OVZ A;  3HY9 A;  1DMT A;  2W12 A;  4H82 A;  3LMC A;  4L7A A;  2V4B A;  1Q3A A;  1KUI A;  1KBC A;  1KUF A;  3KEC A;  2DW1 A;  4JQG A;  3P24 A;  3KMC A;  1JKY A;  3B92 A;  1RM8 A;  5L79 A;  1G4K A;  3LQ0 A;  3WV3 A;  3AIG A;  3LEA A;  2L0R A;  1CXV A;  3LUM A;  3KEK A;  456C A;  1OM7 A;  1KUH A;  1JAP A;  1SMP A;  2FV5 A;  2ERQ A;  1D7X A;  3HBV P;  1CIZ A;  2POJ A;  3F17 A;  4AYK A;  3P1V A;  3DTE A;  3DSL A;  1MMP A;  4WKE A;  3DTK A;  5D1T A;  4PKR A;  2ERP A;  4PKW A;  1CQR A;  1KUK A;  2W14 A;  2E3X A;  1BZS A;  4IJO A;  1BQQ M;  2OW9 A;  3HDB A;  2J83 A;  3DL1 A;  2OW2 A;  3N2U A;  4XCT A;  3EDH A;  1S4B P;  3OHO A;  2YIG A;  3EHY A;  2OZR A;  2JT5 A;  966C A;  3HB2 P;  3E8R A;  4H76 A;  1IAD A;  2MLR A;  3EDG A;  4JPA A;  2X3C A;  4PKS A;  3BA0 A;  3RTT A;  1IAE A;  3NX7 A;  2XS3 A;  1XM5 A;  1H71 P;  3LE9 A;  2QPJ A;  3B2Z A;  1HFS A;  1CGL A;  1ZTQ A;  4FVL A;  1ZS0 A;  1R54 A;  1FBL A;  1CK7 A;  1KUG A;  3KWV C;  4JA1 A;  1B8Y A;  1GKD A;  5I43 A;  1C8T A;  4AXQ A;  1GO7 P;  3EDZ A;  3F19 A;  1EAK A;  4PKT A;  5B5P A;  4A3W A;  3LJT A;  1OS9 A;  1MMQ A;  4H30 A;  2JIH A;  3LKA A;  5BPA A;  4DD8 A;  3N2V A;  2X3B A;  3LIR A;  5B5O A;  1YOU A;  4I03 A;  2O3E A;  1UTT A;  3LIL A;  3OHL A;  2X3A A;  2W15 A;  4H49 A;  3ELM A;  4PKV A;  1GO8 P;  1PWV A;  5I0L A;  1QJJ A;  1JIW P;  3ZUK A;  1JAO A;  1PWU A;  1XFY A;  3DPF A;  1XFU A;  4FXY P;  3LJZ A;  5CZM A;  1A85 A;  1BUD A;  4GR0 A;  4HMA A;  2OY4 A;  2TCL A;  2J0T A;  1G9K A;  4XM6 A;  1I73 A;  1BQO A;  1PWQ A;  4GQL A;  5CXA A;  1XUD A;  1HV5 A;  1ZXV A;  1BKC A; 
#chains in the Genus database with same CATH homology
 1OM8 A;  2MLS A;  2FV9 A;  1BSW A;  1G12 A;  5D1U A;  1UMT A;  3LIK A;  4DV8 A;  4QKZ A;  4IUW A;  3HYG A;  1JK3 A;  2YUF A;  1HY7 A;  1ATL A;  1L6J A;  1UMS A;  2WO9 A;  1XFX A;  3WV2 A;  1HFC A;  4PKQ A;  4XBH A;  5D1S A;  3O2X A;  2W0D A;  3LQB A;  2USN A;  2Z2D A;  1CGF A;  1Z3J A;  4ZR5 A;  1K7G A;  3HBU P;  1USN A;  2ERO A;  2XS4 A;  1QIC A;  5JMY A;  2OXU A;  4GR8 A;  5LAB A;  1MNC A;  1ZVX A;  2I47 A;  1ZP5 A;  4XM8 A;  3RTS A;  3HY7 A;  3F18 A;  4WK7 A;  1BIW A;  1YP1 A;  1PWP A;  3DTI A;  3KRY A;  4H84 A;  1ZXC A;  5D7W A;  1SLM A;  1CAQ A;  3Q2G A;  3L0T A;  3Q2H A;  1FM1 A;  1HOV A;  4G9L A;  2W13 A;  3LJG A;  2JT6 A;  4H3X A;  1GE7 A;  2AYK A;  3G5C A;  2D1N A;  2WOA A;  1QUA A;  4EFS A;  1JIZ A;  1K7I A;  3TSK A;  3LK8 A;  3ZVS A;  3ZXH A;  1MMB A;  1D8M A;  2OXZ A;  1IAG A;  1D8F A;  1GKC A;  2DDY A;  1I76 A;  3EDI A;  4L19 A;  3USN A;  3TS4 A;  3GBO A;  2YB9 A;  1WNI A;  5D2B A;  1OMJ A;  1EUB A;  3G42 A;  4GUY A;  1KAP P;  1OO9 A;  3MA2 A;  2K2G A;  3AYU A;  4FXQ A;  4JIJ A;  1O0Q A;  3UVC A;  1C3I A;  2OVX A;  2DW2 A;  2OW1 A;  5BOT A;  1G49 A;  3AYK A;  3DWB A;  1JAQ A;  1XFV A;  3TT4 A;  4GR3 A;  1R1H A;  2E2D A;  5L7F A;  1AKL A;  3VI1 A;  1JJ9 A;  2CLT A;  1XFZ A;  1PWW A;  2CKI A;  1IAC A;  1AYK A;  3LGP A;  1C7K A;  4WF6 A;  1EB6 A;  4JP4 A;  4A7B A;  1AST A;  1UEA A;  2KRJ A;  4L6T A;  1Y93 A;  1AF0 A;  1Y8J A;  3HDA P;  4H2E A;  1ROS A;  2DW0 A;  1I1I P;  2MZE A;  3K7N A;  3SHI A;  2OI0 A;  3F16 A;  3VTG A;  5BOY A;  3DNG A;  1MMR A;  2PJT A;  4I35 A;  3TVC A;  1RMZ A;  4XM7 A;  4WZV A;  1XUR A;  1GE6 A;  2HU6 A;  4GWM A;  2K9C A;  4CTH A;  5D3C A;  1R1J A;  1B3D A;  3LUN A;  2D1O A;  2JSD A;  2DDF A;  1SLN A;  1GE5 A;  1R1I A;  3V96 B;  4ILW D;  4L63 A;  1XUC A;  3KHI A;  4WKI A;  2N8R A;  3I7G A;  5CUH A;  1SAT A;  2O36 A;  2Y6C A;  4DPE A;  4AUO A;  830C A;  1XFW A;  2AIG P;  4GWN A;  3I7I A;  1JAN A;  1HTD A;  4R3V A;  3F15 A;  3DPE A;  4ON1 A;  4DF9 A;  5I2Z A;  1D5J A;  3B8Z A;  1OM6 A;  1QIA A;  5I3M A;  2OY2 A;  3L0V A;  1O0T A;  2RJQ A;  1QIB A;  2A8H A;  2MZH A;  2OXW A;  3EHX A;  3EWJ A;  4HX3 A;  3O64 A;  1DTH A;  1JH1 A;  1ND1 A;  4FU4 A;  4G0D A;  4AIG A;  4PKU A;  2X7M A;  1OS2 A;  1FLS A;  1G05 A;  2SRT A;  2JNP A;  4Q1L A;  1YQY A;  3CKI A;  1YCM A;  3K7L A;  1GXD A;  4IN9 A;  1UTZ A;  2OW0 A;  3KEJ A;  4GF1 A;  1A86 A;  1BKC E;  1R55 A;  1BKC I;  4H1Q A;  2RJP A;  1Y0V A;  5I4O A;  1J7N A;  1SU3 A;  2WO8 A;  1IAB A;  5I12 A;  1SRP A;  1IAA A;  1CGE A;  1BUV M;  2Y6D A;  3U1R A;  4J4M A;  1K7Q A;  3WV1 A;  1BM6 A;  2MZI A;  3F1A A;  5H8X A;  1QJI A;  3KME A;  2OVZ A;  3HY9 A;  1DMT A;  2W12 A;  4H82 A;  3LMC A;  4L7A A;  2V4B A;  1Q3A A;  1KUI A;  1KBC A;  1KUF A;  3KEC A;  2DW1 A;  4JQG A;  3P24 A;  3KMC A;  1JKY A;  3B92 A;  1RM8 A;  5L79 A;  1G4K A;  3LQ0 A;  3WV3 A;  3AIG A;  3LEA A;  2L0R A;  1CXV A;  3LUM A;  3KEK A;  456C A;  1OM7 A;  1KUH A;  1JAP A;  1SMP A;  2FV5 A;  2ERQ A;  1D7X A;  3HBV P;  1CIZ A;  2POJ A;  3F17 A;  4AYK A;  3P1V A;  3DTE A;  3DSL A;  1MMP A;  4WKE A;  3DTK A;  5D1T A;  4PKR A;  2ERP A;  4PKW A;  1CQR A;  1KUK A;  2W14 A;  2E3X A;  1BZS A;  4IJO A;  1BQQ M;  2OW9 A;  3HDB A;  2J83 A;  3DL1 A;  2OW2 A;  3N2U A;  4XCT A;  3EDH A;  1S4B P;  3OHO A;  2YIG A;  3EHY A;  2OZR A;  2JT5 A;  966C A;  3HB2 P;  3E8R A;  4H76 A;  1IAD A;  2MLR A;  3EDG A;  4JPA A;  2X3C A;  4PKS A;  3BA0 A;  3RTT A;  1IAE A;  3NX7 A;  2XS3 A;  1H71 P;  3LE9 A;  2QPJ A;  3B2Z A;  1HFS A;  1CGL A;  1ZTQ A;  4FVL A;  1ZS0 A;  1R54 A;  1FBL A;  1CK7 A;  1KUG A;  3KWV C;  4JA1 A;  1B8Y A;  1GKD A;  5I43 A;  1C8T A;  4AXQ A;  1GO7 P;  3EDZ A;  3F19 A;  1EAK A;  4PKT A;  5B5P A;  4A3W A;  3LJT A;  1OS9 A;  1MMQ A;  4H30 A;  2JIH A;  3LKA A;  5BPA A;  4DD8 A;  3N2V A;  2X3B A;  3LIR A;  5B5O A;  1YOU A;  4I03 A;  2O3E A;  1UTT A;  3LIL A;  3OHL A;  2X3A A;  2W15 A;  4H49 A;  3ELM A;  4PKV A;  1GO8 P;  1PWV A;  5I0L A;  1QJJ A;  1JIW P;  3ZUK A;  1JAO A;  1PWU A;  1XFY A;  3DPF A;  1XFU A;  4FXY P;  3LJZ A;  5CZM A;  1A85 A;  1BUD A;  4GR0 A;  4HMA A;  2OY4 A;  2TCL A;  2J0T A;  1G9K A;  4XM6 A;  1I73 A;  1BQO A;  1PWQ A;  4GQL A;  5CXA A;  1XUD A;  1HV5 A;  1ZXV A;  1BKC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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