3KMEA

Crystal structure of catalytic domain of tace with phenyl-pyrrolidinyl-tartrate inhibitor
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
257
structure length
253
Chain Sequence
PDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYGGSPHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The discovery of novel tartrate-based TNF-alpha converting enzyme (TACE) inhibitors.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords TNF-alpha-converting enzyme
total genus 80
structure length 253
sequence length 257
chains with identical sequence B
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2009-11-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3kmeA00
3KEKA 4GR8A 3ZVSA 1JK3A 1GKCA 3EDIA 5I3MA 1HV5A 1KUGA 3B8ZA 1GKDA 2YB9A 1XFVA 3LEAA 3LUMA 1HY7A 2OY4A 2Y6CA 3SHIA 3L0TA 3O64A 1Y93A 3AIGA 1SMPA 2ERPA 3LIKA 4GR3A 4XM8A 4AYKA 1ATLA 2MZEA 3HBVP 1RM8A 1Y8JA 1OO9A 1R1HA 4FXYP 1ZTQA 1K7GA 3EHXA 1G9KA 2DDFA 5B5OA 3WV3A 3F1AA 1XFYA 1AF0A 3RTSA 4DD8A 2XS3A 2N8RA 4H3XA 3I7GA 1L6JA 1FBLA 1SLMA 4PKQA 3K7LA 4JP4A 2J83A 3ZUKA 2PJTA 4WKIA 1Q3AA 3LQ0A 1R1IA 1ZXVA 1S4BP 1I1IP 5D2BA 1XUDA 2OY2A 5BOYA 1HFSA 4IJOA 1C8TA 4JA1A 1KUKA 1JKYA 1WNIA 1PWQA 4H30A 1KUIA 2FV9A 3LJZA 1G12A 3KRYA 3U1RA 2SRTA 1PWUA 4H76A 1GXDA 1JIWP 3EDHA 1CIZA 4H84A 1KUHA 1CGEA 3HB2P 3OHOA 4Q1LA 1MMQA 2X3BA 3GBOA 1D8FA 2CLTA 1AYKA 3G42A 4J4MA 1BUDA 1BZSA 1R1JA 1K7QA 1UEAA 2I47A 2E2DA 4H49A 3LE9A 5I0LA 4DV8A 2X3AA 4R3VA 3F15A 1BKCE 1D8MA 3N2UA 1J7NA 1BQQM 5I2ZA 4PKSA 3LIRA 966CA 5BOTA 2RJPA 3LILA 2D1NA 4GWMA 2AYKA 2D1OA 4DF9A 4AUOA 3HDBA 1JAOA 4PKVA 1D5JA 1C3IA 4A3WA 3HYGA 2MLRA 4H82A 2USNA 1CXVA 3DSLA 3DPEA 5L7FA 4HMAA 4PKUA 1O0TA 4GUYA 4JQGA 1JAPA 4DPEA 1QICA 1GO7P 2O36A 4AIGA 1DMTA 2WO9A 3EHYA 2X3CA 3AYKA 1EAKA 3G5CA 2AIGP 1AKLA 1XFWA 2OI0A 1IAGA 3KEJA 1ZXCA 1OM8A 1OM6A 1QIBA 3LK8A 1YP1A 3E8RA 3DWBA 1QUAA 1K7IA 3UVCA 1CGLA 3RTTA 2HU6A 5JMYA 2OW2A 1IACA 2V4BA 3KHIA 1H71P 1FLSA 4IUWA 1A85A 1BUVM 4EFSA 1IAAA 3LJGA 1QJJA 3LKAA 3V96B 2X7MA 2OW9A 1YQYA 4ILWD 1JAQA 1UTZA 2E3XA 5BPAA 4GQLA 1MMBA 5D3CA 2O3EA 4FVLA 1PWWA 2JIHA 3CKIA 1GE6A 3F19A 1ZS0A 3LUNA 5D7WA 4JPAA 2MZHA 3KECA 4JIJA 4WKEA 4HX3A 2W0DA 2DW0A 1BSWA 1KUFA 3P1VA 2QPJA 1MNCA 1SRPA 1O0QA 2K2GA 3HY7A 1UMTA 2OXZA 3TSKA 1B3DA 3B92A 1BKCI 3TS4A 4IN9A 1PWPA 3HDAP 1BKCA 1XURA 1I73A 4WZVA 2OXWA 5I12A 1Z3JA 1KAPP 1ROSA 4GWNA 5D1UA 5L79A 3DNGA 2K9CA 4I35A 4QKZA 1SU3A 3F18A 2JNPA 5D1TA 3LGPA 4WK7A 5CZMA 2XS4A 4A7BA 5D1SA 3HY9A 3EDZA 1ASTA 2YIGA 1G49A 2OXUA 4G0DA 1HOVA 1CAQA 1G4KA 5I43A 3Q2GA 1RMZA 3DPFA 1Y0VA 1OS2A 3N2VA 3KWVC 2Z2DA 3NX7A 2DDYA 4WF6A 4GF1A 3F17A 1JANA 3MA2A 3O2XA 1DTHA 1BQOA 2OVXA 3OHLA 1XUCA 2FV5A 1YOUA 4XM7A 3LJTA 1UTTA 2A8HA 1IABA 1C7KA 4CTHA 4ZR5A 3VTGA 1SLNA 3LMCA 3EDGA 5H8XA 4L6TA 3HBUP 2W15A 3F16A 4XM6A 2L0RA 3Q2HA 2W13A 4G9LA 2TCLA 1R54A 3K7NA 1HTDA 1OM7A 2W12A 1G05A 1A86A 3ELMA 3I7IA 4AXQA 2OW0A 1SATA 1XFXA 1USNA 3USNA 5CXAA 4L63A 3DL1A 3L0VA 4PKTA 2Y6DA 4H2EA 2KRJA 4FXQA 2EROA 830CA 1GO8P 1JH1A 1IAEA 1D7XA 2J0TA 3ZXHA 1UMSA 1BIWA 1EB6A 2DW1A 1GE5A 3LQBA 1FM1A 5I4OA 4FU4A 5B5PA 1OMJA 5CUHA 3TT4A 2OW1A 4ON1A 1JJ9A 1B8YA 4XBHA 2WOAA 3VI1A 2ERQA 1R55A 3TVCA 1XFZA 1CQRA 1ND1A 1JIZA 4L19A 3BA0A 1BM6A 4XCTA 2CKIA 2OVZA 4H1QA 1IADA 1ZP5A 2JSDA 5LABA 1KBCA 1QIAA 1XFUA 1PWVA 1EUBA 456CA 4GR0A 2DW2A 3P24A 1GE7A 2OZRA 2RJQA 3WV2A 1MMRA 3B2ZA 1YCMA 1ZVXA 1OS9A 1I76A 1QJIA 4I03A 3KMEA 3WV1A 3AYUA 1MMPA 3EWJA 2POJA 1CGFA 4PKRA 2WO8A 1CK7A 2W14A 2JT5A 2MZIA 3KMCA 4PKWA 1HFCA 2JT6A 2MLSA
chains in the Genus database with same CATH superfamily
3KEKA 4GR8A 3ZVSA 1JK3A 1GKCA 3EDIA 5I3MA 1HV5A 1KUGA 3B8ZA 1GKDA 3DTKA 2YB9A 1XFVA 3LEAA 3LUMA 1HY7A 2OY4A 2Y6CA 3SHIA 3L0TA 3O64A 1Y93A 3AIGA 1SMPA 2ERPA 3LIKA 4GR3A 4XM8A 4AYKA 1ATLA 2MZEA 3HBVP 1RM8A 1Y8JA 1OO9A 1R1HA 4FXYP 1ZTQA 1K7GA 3EHXA 1G9KA 2DDFA 5B5OA 3WV3A 3F1AA 1XFYA 1AF0A 3RTSA 4DD8A 2XS3A 2N8RA 4H3XA 3I7GA 1L6JA 1FBLA 1SLMA 4PKQA 3K7LA 4JP4A 2J83A 3ZUKA 2PJTA 4WKIA 1Q3AA 3LQ0A 1R1IA 1ZXVA 1S4BP 1I1IP 5D2BA 1XUDA 2OY2A 5BOYA 1HFSA 4IJOA 1C8TA 4JA1A 1KUKA 1JKYA 1WNIA 1PWQA 4H30A 1KUIA 2FV9A 3LJZA 1G12A 3KRYA 3U1RA 2SRTA 1PWUA 4H76A 1GXDA 1JIWP 3EDHA 1CIZA 4H84A 1KUHA 1CGEA 3HB2P 3OHOA 4Q1LA 1TVIA 1MMQA 2X3BA 3GBOA 1D8FA 2CLTA 1AYKA 3G42A 4J4MA 1BUDA 1BZSA 1R1JA 1K7QA 1UEAA 2I47A 2E2DA 4H49A 3LE9A 5I0LA 4DV8A 2X3AA 4R3VA 3F15A 1BKCE 1D8MA 3N2UA 1J7NA 1BQQM 5I2ZA 4PKSA 3LIRA 966CA 5BOTA 2RJPA 3LILA 2D1NA 4GWMA 2AYKA 2D1OA 4DF9A 4AUOA 3HDBA 1JAOA 4PKVA 1D5JA 1C3IA 4A3WA 3HYGA 2MLRA 4H82A 2USNA 1CXVA 3DSLA 3DPEA 5L7FA 4HMAA 4PKUA 1O0TA 4GUYA 4JQGA 1JAPA 4DPEA 1QICA 1GO7P 2O36A 4AIGA 1DMTA 2WO9A 3EHYA 2X3CA 3AYKA 1EAKA 3G5CA 2AIGP 1AKLA 1XFWA 2OI0A 1IAGA 3KEJA 1ZXCA 1OM8A 1OM6A 1QIBA 3LK8A 1YP1A 3E8RA 3DWBA 1QUAA 1K7IA 3UVCA 1CGLA 3RTTA 1XAXA 2HU6A 5JMYA 2OW2A 1IACA 2V4BA 3KHIA 1H71P 1FLSA 4IUWA 1A85A 1BUVM 4EFSA 1IAAA 3LJGA 1QJJA 3LKAA 3V96B 2X7MA 2OW9A 1YQYA 4ILWD 1JAQA 1UTZA 2E3XA 5BPAA 4GQLA 1MMBA 5D3CA 2O3EA 4FVLA 1PWWA 2JIHA 3CKIA 1GE6A 3F19A 1ZS0A 3LUNA 5D7WA 4JPAA 2MZHA 3KECA 4JIJA 4WKEA 4HX3A 2W0DA 2DW0A 1BSWA 1KUFA 3P1VA 2QPJA 1MNCA 1SRPA 1O0QA 2K2GA 3HY7A 1UMTA 2OXZA 3TSKA 1B3DA 3B92A 1BKCI 3TS4A 4IN9A 1PWPA 3HDAP 1BKCA 1XURA 1I73A 4WZVA 2OXWA 5I12A 1Z3JA 1KAPP 1ROSA 4GWNA 5D1UA 5L79A 3DNGA 2K9CA 4I35A 4QKZA 1SU3A 3F18A 2JNPA 3DTEA 3LGPA 4WK7A 5CZMA 5D1TA 2XS4A 4A7BA 5D1SA 3HY9A 3EDZA 4L7AA 1ASTA 2YIGA 1G49A 2OXUA 4G0DA 1HOVA 1CAQA 1G4KA 5I43A 3Q2GA 1RMZA 3DPFA 1Y0VA 1OS2A 3N2VA 3KWVC 2Z2DA 3NX7A 2DDYA 4WF6A 4GF1A 3F17A 1JANA 3MA2A 3O2XA 1DTHA 1BQOA 2OVXA 3OHLA 1XUCA 2FV5A 1YOUA 4XM7A 3LJTA 1UTTA 2A8HA 1IABA 1C7KA 4CTHA 4ZR5A 3VTGA 1SLNA 3LMCA 3EDGA 5H8XA 4L6TA 3DTIA 3HBUP 2W15A 3F16A 4XM6A 2L0RA 3Q2HA 2W13A 4G9LA 1XM5A 2TCLA 1R54A 3K7NA 1HTDA 1OM7A 2W12A 1G05A 1A86A 3ELMA 3I7IA 4AXQA 2OW0A 1SATA 1XFXA 1USNA 3USNA 5CXAA 4L63A 3DL1A 3L0VA 4PKTA 2Y6DA 4H2EA 2KRJA 4FXQA 2EROA 830CA 1GO8P 1JH1A 1IAEA 1D7XA 2J0TA 3ZXHA 1UMSA 1BIWA 1EB6A 2DW1A 1GE5A 3LQBA 1FM1A 5I4OA 2YUFA 4FU4A 5B5PA 1OMJA 5CUHA 3TT4A 2OW1A 4ON1A 1JJ9A 1B8YA 4XBHA 2WOAA 1OZ9A 3VI1A 2ERQA 1R55A 3TVCA 1XFZA 1CQRA 1ND1A 1JIZA 4L19A 3BA0A 1BM6A 4XCTA 2CKIA 2OVZA 4H1QA 1IADA 1ZP5A 2JSDA 5LABA 1KBCA 1QIAA 1XFUA 1PWVA 1EUBA 456CA 4GR0A 2DW2A 3P24A 1GE7A 2OZRA 2RJQA 3WV2A 1MMRA 3B2ZA 1YCMA 1ZVXA 1OS9A 1I76A 1QJIA 4I03A 3KMEA 3WV1A 3AYUA 1MMPA 3EWJA 2POJA 1CGFA 4PKRA 2WO8A 1CK7A 2W14A 2JT5A 2MZIA 3KMCA 4PKWA 1HFCA 2JT6A 2MLSA
chains in the Genus database with same CATH topology
3KEKA 4GR8A 3ZVSA 1JK3A 1GKCA 3EDIA 5I3MA 1HV5A 1KUGA 3B8ZA 1GKDA 3DTKA 2YB9A 1XFVA 3LEAA 3LUMA 1HY7A 2OY4A 2Y6CA 3SHIA 3L0TA 3O64A 1Y93A 3AIGA 1SMPA 2ERPA 3LIKA 4GR3A 4XM8A 4AYKA 1ATLA 2MZEA 3HBVP 1RM8A 1Y8JA 1OO9A 1R1HA 4FXYP 1ZTQA 1K7GA 3EHXA 1G9KA 2DDFA 5B5OA 3WV3A 3F1AA 1XFYA 1AF0A 3RTSA 4DD8A 2XS3A 2N8RA 4H3XA 3I7GA 1L6JA 1FBLA 1SLMA 4PKQA 3K7LA 4JP4A 2J83A 3ZUKA 2PJTA 4WKIA 1Q3AA 3LQ0A 1R1IA 1ZXVA 1S4BP 1I1IP 5D2BA 1XUDA 2OY2A 5BOYA 1HFSA 4IJOA 1C8TA 4JA1A 1KUKA 1JKYA 1WNIA 1PWQA 4H30A 1KUIA 2FV9A 3LJZA 1G12A 3KRYA 3U1RA 2SRTA 1PWUA 4H76A 1GXDA 1JIWP 3EDHA 1CIZA 4H84A 1KUHA 1CGEA 3HB2P 3OHOA 4Q1LA 1MMQA 2X3BA 3GBOA 1D8FA 2CLTA 1AYKA 3G42A 4J4MA 1BUDA 1BZSA 1R1JA 1K7QA 1UEAA 2I47A 2E2DA 4H49A 3LE9A 5I0LA 4DV8A 2X3AA 4R3VA 3F15A 1BKCE 1D8MA 3N2UA 1J7NA 1BQQM 5I2ZA 4PKSA 3LIRA 966CA 5BOTA 2RJPA 3LILA 2D1NA 4GWMA 2AYKA 2D1OA 4DF9A 4AUOA 3HDBA 1JAOA 4PKVA 1D5JA 1C3IA 4A3WA 3HYGA 2MLRA 4H82A 2USNA 1CXVA 3DSLA 3DPEA 5L7FA 4HMAA 4PKUA 1O0TA 4GUYA 4JQGA 1JAPA 4DPEA 1QICA 1GO7P 2O36A 4AIGA 1DMTA 2WO9A 3EHYA 2X3CA 3AYKA 1EAKA 3G5CA 2AIGP 1AKLA 1XFWA 2OI0A 1IAGA 3KEJA 1ZXCA 1OM8A 1OM6A 1QIBA 3LK8A 1YP1A 3E8RA 3DWBA 1QUAA 1K7IA 3UVCA 1CGLA 3RTTA 2HU6A 5JMYA 2OW2A 1IACA 2V4BA 3KHIA 1H71P 1FLSA 4IUWA 1A85A 1BUVM 4EFSA 1IAAA 3LJGA 1QJJA 3LKAA 3V96B 2X7MA 2OW9A 1YQYA 4ILWD 1JAQA 1UTZA 2E3XA 5BPAA 4GQLA 1MMBA 5D3CA 2O3EA 4FVLA 1PWWA 2JIHA 3CKIA 1GE6A 3F19A 1ZS0A 3LUNA 5D7WA 4JPAA 2MZHA 3KECA 4JIJA 4WKEA 4HX3A 2W0DA 2DW0A 1BSWA 1KUFA 3P1VA 2QPJA 1MNCA 1SRPA 1O0QA 2K2GA 3HY7A 1UMTA 2OXZA 3TSKA 1B3DA 3B92A 1BKCI 3TS4A 4IN9A 1PWPA 3HDAP 1BKCA 1XURA 1I73A 4WZVA 2OXWA 5I12A 1Z3JA 1KAPP 1ROSA 4GWNA 5D1UA 5L79A 3DNGA 2K9CA 4I35A 4QKZA 1SU3A 3F18A 2JNPA 3DTEA 3LGPA 4WK7A 5CZMA 5D1TA 2XS4A 4A7BA 5D1SA 3HY9A 3EDZA 4L7AA 1ASTA 2YIGA 1G49A 2OXUA 4G0DA 1HOVA 1CAQA 1G4KA 5I43A 3Q2GA 1RMZA 3DPFA 1Y0VA 1OS2A 3N2VA 3KWVC 2Z2DA 3NX7A 2DDYA 4WF6A 4GF1A 3F17A 1JANA 3MA2A 3O2XA 1DTHA 1BQOA 2OVXA 3OHLA 1XUCA 2FV5A 1YOUA 4XM7A 3LJTA 1UTTA 2A8HA 1IABA 1C7KA 4CTHA 4ZR5A 3VTGA 1SLNA 3LMCA 3EDGA 5H8XA 4L6TA 3DTIA 3HBUP 2W15A 3F16A 4XM6A 2L0RA 3Q2HA 2W13A 4G9LA 2TCLA 1R54A 3K7NA 1HTDA 1OM7A 2W12A 1G05A 1A86A 3ELMA 3I7IA 4AXQA 2OW0A 1SATA 1XFXA 1USNA 3USNA 5CXAA 4L63A 3DL1A 3L0VA 4PKTA 2Y6DA 4H2EA 2KRJA 4FXQA 2EROA 830CA 1GO8P 1JH1A 1IAEA 1D7XA 2J0TA 3ZXHA 1UMSA 1BIWA 1EB6A 2DW1A 1GE5A 3LQBA 1FM1A 5I4OA 2YUFA 4FU4A 5B5PA 1OMJA 5CUHA 3TT4A 2OW1A 4ON1A 1JJ9A 1B8YA 4XBHA 2WOAA 3VI1A 2ERQA 1R55A 3TVCA 1XFZA 1CQRA 1ND1A 1JIZA 4L19A 3BA0A 1BM6A 4XCTA 2CKIA 2OVZA 4H1QA 1IADA 1ZP5A 2JSDA 5LABA 1KBCA 1QIAA 1XFUA 1PWVA 1EUBA 456CA 4GR0A 2DW2A 3P24A 1GE7A 2OZRA 2RJQA 3WV2A 1MMRA 3B2ZA 1YCMA 1ZVXA 1OS9A 1I76A 1QJIA 4I03A 3KMEA 3WV1A 3AYUA 1MMPA 3EWJA 2POJA 1CGFA 4PKRA 2WO8A 1CK7A 2W14A 2JT5A 2MZIA 3KMCA 4PKWA 1HFCA 2JT6A 2MLSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KEK A;  4GR8 A;  3ZVS A;  1JK3 A;  1GKC A;  3EDI A;  5I3M A;  1HV5 A;  1KUG A;  3B8Z A;  1GKD A;  2YB9 A;  1XFV A;  3LEA A;  3LUM A;  1HY7 A;  2OY4 A;  2Y6C A;  3SHI A;  3L0T A;  3O64 A;  1Y93 A;  3AIG A;  1SMP A;  2ERP A;  3LIK A;  4GR3 A;  4XM8 A;  4AYK A;  1ATL A;  2MZE A;  3HBV P;  1RM8 A;  1Y8J A;  1OO9 A;  1R1H A;  4FXY P;  1ZTQ A;  1K7G A;  3EHX A;  1G9K A;  2DDF A;  5B5O A;  3WV3 A;  3F1A A;  1XFY A;  1AF0 A;  3RTS A;  4DD8 A;  2XS3 A;  2N8R A;  4H3X A;  3I7G A;  1L6J A;  1FBL A;  1SLM A;  4PKQ A;  3K7L A;  4JP4 A;  2J83 A;  3ZUK A;  2PJT A;  4WKI A;  1Q3A A;  3LQ0 A;  1R1I A;  1ZXV A;  1S4B P;  1I1I P;  5D2B A;  1XUD A;  2OY2 A;  5BOY A;  1HFS A;  4IJO A;  1C8T A;  4JA1 A;  1KUK A;  1JKY A;  1WNI A;  1PWQ A;  4H30 A;  1KUI A;  2FV9 A;  3LJZ A;  1G12 A;  3KRY A;  3U1R A;  2SRT A;  1PWU A;  4H76 A;  1GXD A;  1JIW P;  3EDH A;  1CIZ A;  4H84 A;  1KUH A;  1CGE A;  3HB2 P;  3OHO A;  4Q1L A;  1MMQ A;  2X3B A;  3GBO A;  1D8F A;  2CLT A;  1AYK A;  3G42 A;  4J4M A;  1BUD A;  1BZS A;  1R1J A;  1K7Q A;  1UEA A;  2I47 A;  2E2D A;  4H49 A;  3LE9 A;  5I0L A;  4DV8 A;  2X3A A;  4R3V A;  3F15 A;  1BKC E;  1D8M A;  3N2U A;  1J7N A;  1BQQ M;  5I2Z A;  4PKS A;  3LIR A;  966C A;  5BOT A;  2RJP A;  3LIL A;  2D1N A;  4GWM A;  2AYK A;  2D1O A;  4DF9 A;  4AUO A;  3HDB A;  1JAO A;  4PKV A;  1D5J A;  1C3I A;  4A3W A;  3HYG A;  2MLR A;  4H82 A;  2USN A;  1CXV A;  3DSL A;  3DPE A;  5L7F A;  4HMA A;  4PKU A;  1O0T A;  4GUY A;  4JQG A;  1JAP A;  4DPE A;  1QIC A;  1GO7 P;  2O36 A;  4AIG A;  1DMT A;  2WO9 A;  3EHY A;  2X3C A;  3AYK A;  1EAK A;  3G5C A;  2AIG P;  1AKL A;  1XFW A;  2OI0 A;  1IAG A;  3KEJ A;  1ZXC A;  1OM8 A;  1OM6 A;  1QIB A;  3LK8 A;  1YP1 A;  3E8R A;  3DWB A;  1QUA A;  1K7I A;  3UVC A;  1CGL A;  3RTT A;  2HU6 A;  5JMY A;  2OW2 A;  1IAC A;  2V4B A;  3KHI A;  1H71 P;  1FLS A;  4IUW A;  1A85 A;  1BUV M;  4EFS A;  1IAA A;  3LJG A;  1QJJ A;  3LKA A;  3V96 B;  2X7M A;  2OW9 A;  1YQY A;  4ILW D;  1JAQ A;  1UTZ A;  2E3X A;  5BPA A;  4GQL A;  1MMB A;  5D3C A;  2O3E A;  4FVL A;  1PWW A;  2JIH A;  3CKI A;  1GE6 A;  3F19 A;  1ZS0 A;  3LUN A;  5D7W A;  4JPA A;  2MZH A;  3KEC A;  4JIJ A;  4WKE A;  4HX3 A;  2W0D A;  2DW0 A;  1BSW A;  1KUF A;  3P1V A;  2QPJ A;  1MNC A;  1SRP A;  1O0Q A;  2K2G A;  3HY7 A;  1UMT A;  2OXZ A;  3TSK A;  1B3D A;  3B92 A;  1BKC I;  3TS4 A;  4IN9 A;  1PWP A;  3HDA P;  1BKC A;  1XUR A;  1I73 A;  4WZV A;  2OXW A;  5I12 A;  1Z3J A;  1KAP P;  1ROS A;  4GWN A;  5D1U A;  5L79 A;  3DNG A;  2K9C A;  4I35 A;  4QKZ A;  1SU3 A;  3F18 A;  2JNP A;  5D1T A;  3LGP A;  4WK7 A;  5CZM A;  2XS4 A;  4A7B A;  5D1S A;  3HY9 A;  3EDZ A;  1AST A;  2YIG A;  1G49 A;  2OXU A;  4G0D A;  1HOV A;  1CAQ A;  1G4K A;  5I43 A;  3Q2G A;  1RMZ A;  3DPF A;  1Y0V A;  1OS2 A;  3N2V A;  3KWV C;  2Z2D A;  3NX7 A;  2DDY A;  4WF6 A;  4GF1 A;  3F17 A;  1JAN A;  3MA2 A;  3O2X A;  1DTH A;  1BQO A;  2OVX A;  3OHL A;  1XUC A;  2FV5 A;  1YOU A;  4XM7 A;  3LJT A;  1UTT A;  2A8H A;  1IAB A;  1C7K A;  4CTH A;  4ZR5 A;  3VTG A;  1SLN A;  3LMC A;  3EDG A;  5H8X A;  4L6T A;  3HBU P;  2W15 A;  3F16 A;  4XM6 A;  2L0R A;  3Q2H A;  2W13 A;  4G9L A;  2TCL A;  1R54 A;  3K7N A;  1HTD A;  1OM7 A;  2W12 A;  1G05 A;  1A86 A;  3ELM A;  3I7I A;  4AXQ A;  2OW0 A;  1SAT A;  1XFX A;  1USN A;  3USN A;  5CXA A;  4L63 A;  3DL1 A;  3L0V A;  4PKT A;  2Y6D A;  4H2E A;  2KRJ A;  4FXQ A;  2ERO A;  830C A;  1GO8 P;  1JH1 A;  1IAE A;  1D7X A;  2J0T A;  3ZXH A;  1UMS A;  1BIW A;  1EB6 A;  2DW1 A;  1GE5 A;  3LQB A;  1FM1 A;  5I4O A;  4FU4 A;  5B5P A;  1OMJ A;  5CUH A;  3TT4 A;  2OW1 A;  4ON1 A;  1JJ9 A;  1B8Y A;  4XBH A;  2WOA A;  3VI1 A;  2ERQ A;  1R55 A;  3TVC A;  1XFZ A;  1CQR A;  1ND1 A;  1JIZ A;  4L19 A;  3BA0 A;  1BM6 A;  4XCT A;  2CKI A;  2OVZ A;  4H1Q A;  1IAD A;  1ZP5 A;  2JSD A;  5LAB A;  1KBC A;  1QIA A;  1XFU A;  1PWV A;  1EUB A;  456C A;  4GR0 A;  2DW2 A;  3P24 A;  1GE7 A;  2OZR A;  2RJQ A;  3WV2 A;  1MMR A;  3B2Z A;  1YCM A;  1ZVX A;  1OS9 A;  1I76 A;  1QJI A;  4I03 A;  3KME A;  3WV1 A;  3AYU A;  1MMP A;  3EWJ A;  2POJ A;  1CGF A;  4PKR A;  2WO8 A;  1CK7 A;  2W14 A;  2JT5 A;  2MZI A;  3KMC A;  4PKW A;  1HFC A;  2JT6 A;  2MLS A; 
#chains in the Genus database with same CATH topology
 3KEK A;  4GR8 A;  3ZVS A;  1JK3 A;  1GKC A;  3EDI A;  5I3M A;  1HV5 A;  1KUG A;  3B8Z A;  1GKD A;  3DTK A;  2YB9 A;  1XFV A;  3LEA A;  3LUM A;  1HY7 A;  2OY4 A;  2Y6C A;  3SHI A;  3L0T A;  3O64 A;  1Y93 A;  3AIG A;  1SMP A;  2ERP A;  3LIK A;  4GR3 A;  4XM8 A;  4AYK A;  1ATL A;  2MZE A;  3HBV P;  1RM8 A;  1Y8J A;  1OO9 A;  1R1H A;  4FXY P;  1ZTQ A;  1K7G A;  3EHX A;  1G9K A;  2DDF A;  5B5O A;  3WV3 A;  3F1A A;  1XFY A;  1AF0 A;  3RTS A;  4DD8 A;  2XS3 A;  2N8R A;  4H3X A;  3I7G A;  1L6J A;  1FBL A;  1SLM A;  4PKQ A;  3K7L A;  4JP4 A;  2J83 A;  3ZUK A;  2PJT A;  4WKI A;  1Q3A A;  3LQ0 A;  1R1I A;  1ZXV A;  1S4B P;  1I1I P;  5D2B A;  1XUD A;  2OY2 A;  5BOY A;  1HFS A;  4IJO A;  1C8T A;  4JA1 A;  1KUK A;  1JKY A;  1WNI A;  1PWQ A;  4H30 A;  1KUI A;  2FV9 A;  3LJZ A;  1G12 A;  3KRY A;  3U1R A;  2SRT A;  1PWU A;  4H76 A;  1GXD A;  1JIW P;  3EDH A;  1CIZ A;  4H84 A;  1KUH A;  1CGE A;  3HB2 P;  3OHO A;  4Q1L A;  1TVI A;  1MMQ A;  2X3B A;  3GBO A;  1D8F A;  2CLT A;  1AYK A;  3G42 A;  4J4M A;  1BUD A;  1BZS A;  1R1J A;  1K7Q A;  1UEA A;  2I47 A;  2E2D A;  4H49 A;  3LE9 A;  5I0L A;  4DV8 A;  2X3A A;  4R3V A;  3F15 A;  1BKC E;  1D8M A;  3N2U A;  1J7N A;  1BQQ M;  5I2Z A;  4PKS A;  3LIR A;  966C A;  5BOT A;  2RJP A;  3LIL A;  2D1N A;  4GWM A;  2AYK A;  2D1O A;  4DF9 A;  4AUO A;  3HDB A;  1JAO A;  4PKV A;  1D5J A;  1C3I A;  4A3W A;  3HYG A;  2MLR A;  4H82 A;  2USN A;  1CXV A;  3DSL A;  3DPE A;  5L7F A;  4HMA A;  4PKU A;  1O0T A;  4GUY A;  4JQG A;  1JAP A;  4DPE A;  1QIC A;  1GO7 P;  2O36 A;  4AIG A;  1DMT A;  2WO9 A;  3EHY A;  2X3C A;  3AYK A;  1EAK A;  3G5C A;  2AIG P;  1AKL A;  1XFW A;  2OI0 A;  1IAG A;  3KEJ A;  1ZXC A;  1OM8 A;  1OM6 A;  1QIB A;  3LK8 A;  1YP1 A;  3E8R A;  3DWB A;  1QUA A;  1K7I A;  3UVC A;  1CGL A;  3RTT A;  1XAX A;  2HU6 A;  5JMY A;  2OW2 A;  1IAC A;  2V4B A;  3KHI A;  1H71 P;  1FLS A;  4IUW A;  1A85 A;  1BUV M;  4EFS A;  1IAA A;  3LJG A;  1QJJ A;  3LKA A;  3V96 B;  2X7M A;  2OW9 A;  1YQY A;  4ILW D;  1JAQ A;  1UTZ A;  2E3X A;  5BPA A;  4GQL A;  1MMB A;  5D3C A;  2O3E A;  4FVL A;  1PWW A;  2JIH A;  3CKI A;  1GE6 A;  3F19 A;  1ZS0 A;  3LUN A;  5D7W A;  4JPA A;  2MZH A;  3KEC A;  4JIJ A;  4WKE A;  4HX3 A;  2W0D A;  2DW0 A;  1BSW A;  1KUF A;  3P1V A;  2QPJ A;  1MNC A;  1SRP A;  1O0Q A;  2K2G A;  3HY7 A;  1UMT A;  2OXZ A;  3TSK A;  1B3D A;  3B92 A;  1BKC I;  3TS4 A;  4IN9 A;  1PWP A;  3HDA P;  1BKC A;  1XUR A;  1I73 A;  4WZV A;  2OXW A;  5I12 A;  1Z3J A;  1KAP P;  1ROS A;  4GWN A;  5D1U A;  5L79 A;  3DNG A;  2K9C A;  4I35 A;  4QKZ A;  1SU3 A;  3F18 A;  2JNP A;  3DTE A;  3LGP A;  4WK7 A;  5CZM A;  5D1T A;  2XS4 A;  4A7B A;  5D1S A;  3HY9 A;  3EDZ A;  4L7A A;  1AST A;  2YIG A;  1G49 A;  2OXU A;  4G0D A;  1HOV A;  1CAQ A;  1G4K A;  5I43 A;  3Q2G A;  1RMZ A;  3DPF A;  1Y0V A;  1OS2 A;  3N2V A;  3KWV C;  2Z2D A;  3NX7 A;  2DDY A;  4WF6 A;  4GF1 A;  3F17 A;  1JAN A;  3MA2 A;  3O2X A;  1DTH A;  1BQO A;  2OVX A;  3OHL A;  1XUC A;  2FV5 A;  1YOU A;  4XM7 A;  3LJT A;  1UTT A;  2A8H A;  1IAB A;  1C7K A;  4CTH A;  4ZR5 A;  3VTG A;  1SLN A;  3LMC A;  3EDG A;  5H8X A;  4L6T A;  3DTI A;  3HBU P;  2W15 A;  3F16 A;  4XM6 A;  2L0R A;  3Q2H A;  2W13 A;  4G9L A;  1XM5 A;  2TCL A;  1R54 A;  3K7N A;  1HTD A;  1OM7 A;  2W12 A;  1G05 A;  1A86 A;  3ELM A;  3I7I A;  4AXQ A;  2OW0 A;  1SAT A;  1XFX A;  1USN A;  3USN A;  5CXA A;  4L63 A;  3DL1 A;  3L0V A;  4PKT A;  2Y6D A;  4H2E A;  2KRJ A;  4FXQ A;  2ERO A;  830C A;  1GO8 P;  1JH1 A;  1IAE A;  1D7X A;  2J0T A;  3ZXH A;  1UMS A;  1BIW A;  1EB6 A;  2DW1 A;  1GE5 A;  3LQB A;  1FM1 A;  5I4O A;  2YUF A;  4FU4 A;  5B5P A;  1OMJ A;  5CUH A;  3TT4 A;  2OW1 A;  4ON1 A;  1JJ9 A;  1B8Y A;  4XBH A;  2WOA A;  1OZ9 A;  3VI1 A;  2ERQ A;  1R55 A;  3TVC A;  1XFZ A;  1CQR A;  1ND1 A;  1JIZ A;  4L19 A;  3BA0 A;  1BM6 A;  4XCT A;  2CKI A;  2OVZ A;  4H1Q A;  1IAD A;  1ZP5 A;  2JSD A;  5LAB A;  1KBC A;  1QIA A;  1XFU A;  1PWV A;  1EUB A;  456C A;  4GR0 A;  2DW2 A;  3P24 A;  1GE7 A;  2OZR A;  2RJQ A;  3WV2 A;  1MMR A;  3B2Z A;  1YCM A;  1ZVX A;  1OS9 A;  1I76 A;  1QJI A;  4I03 A;  3KME A;  3WV1 A;  3AYU A;  1MMP A;  3EWJ A;  2POJ A;  1CGF A;  4PKR A;  2WO8 A;  1CK7 A;  2W14 A;  2JT5 A;  2MZI A;  3KMC A;  4PKW A;  1HFC A;  2JT6 A;  2MLS A; 
#chains in the Genus database with same CATH homology
 3KEK A;  4GR8 A;  3ZVS A;  1JK3 A;  1GKC A;  3EDI A;  5I3M A;  1HV5 A;  1KUG A;  3B8Z A;  1GKD A;  3DTK A;  2YB9 A;  1XFV A;  3LEA A;  3LUM A;  1HY7 A;  2OY4 A;  2Y6C A;  3SHI A;  3L0T A;  3O64 A;  1Y93 A;  3AIG A;  1SMP A;  2ERP A;  3LIK A;  4GR3 A;  4XM8 A;  4AYK A;  1ATL A;  2MZE A;  3HBV P;  1RM8 A;  1Y8J A;  1OO9 A;  1R1H A;  4FXY P;  1ZTQ A;  1K7G A;  3EHX A;  1G9K A;  2DDF A;  5B5O A;  3WV3 A;  3F1A A;  1XFY A;  1AF0 A;  3RTS A;  4DD8 A;  2XS3 A;  2N8R A;  4H3X A;  3I7G A;  1L6J A;  1FBL A;  1SLM A;  4PKQ A;  3K7L A;  4JP4 A;  2J83 A;  3ZUK A;  2PJT A;  4WKI A;  1Q3A A;  3LQ0 A;  1R1I A;  1ZXV A;  1S4B P;  1I1I P;  5D2B A;  1XUD A;  2OY2 A;  5BOY A;  1HFS A;  4IJO A;  1C8T A;  4JA1 A;  1KUK A;  1JKY A;  1WNI A;  1PWQ A;  4H30 A;  1KUI A;  2FV9 A;  3LJZ A;  1G12 A;  3KRY A;  3U1R A;  2SRT A;  1PWU A;  4H76 A;  1GXD A;  1JIW P;  3EDH A;  1CIZ A;  4H84 A;  1KUH A;  1CGE A;  3HB2 P;  3OHO A;  4Q1L A;  1MMQ A;  2X3B A;  3GBO A;  1D8F A;  2CLT A;  1AYK A;  3G42 A;  4J4M A;  1BUD A;  1BZS A;  1R1J A;  1K7Q A;  1UEA A;  2I47 A;  2E2D A;  4H49 A;  3LE9 A;  5I0L A;  4DV8 A;  2X3A A;  4R3V A;  3F15 A;  1BKC E;  1D8M A;  3N2U A;  1J7N A;  1BQQ M;  5I2Z A;  4PKS A;  3LIR A;  966C A;  5BOT A;  2RJP A;  3LIL A;  2D1N A;  4GWM A;  2AYK A;  2D1O A;  4DF9 A;  4AUO A;  3HDB A;  1JAO A;  4PKV A;  1D5J A;  1C3I A;  4A3W A;  3HYG A;  2MLR A;  4H82 A;  2USN A;  1CXV A;  3DSL A;  3DPE A;  5L7F A;  4HMA A;  4PKU A;  1O0T A;  4GUY A;  4JQG A;  1JAP A;  4DPE A;  1QIC A;  1GO7 P;  2O36 A;  4AIG A;  1DMT A;  2WO9 A;  3EHY A;  2X3C A;  3AYK A;  1EAK A;  3G5C A;  2AIG P;  1AKL A;  1XFW A;  2OI0 A;  1IAG A;  3KEJ A;  1ZXC A;  1OM8 A;  1OM6 A;  1QIB A;  3LK8 A;  1YP1 A;  3E8R A;  3DWB A;  1QUA A;  1K7I A;  3UVC A;  1CGL A;  3RTT A;  2HU6 A;  5JMY A;  2OW2 A;  1IAC A;  2V4B A;  3KHI A;  1H71 P;  1FLS A;  4IUW A;  1A85 A;  1BUV M;  4EFS A;  1IAA A;  3LJG A;  1QJJ A;  3LKA A;  3V96 B;  2X7M A;  2OW9 A;  1YQY A;  4ILW D;  1JAQ A;  1UTZ A;  2E3X A;  5BPA A;  4GQL A;  1MMB A;  5D3C A;  2O3E A;  4FVL A;  1PWW A;  2JIH A;  3CKI A;  1GE6 A;  3F19 A;  1ZS0 A;  3LUN A;  5D7W A;  4JPA A;  2MZH A;  3KEC A;  4JIJ A;  4WKE A;  4HX3 A;  2W0D A;  2DW0 A;  1BSW A;  1KUF A;  3P1V A;  2QPJ A;  1MNC A;  1SRP A;  1O0Q A;  2K2G A;  3HY7 A;  1UMT A;  2OXZ A;  3TSK A;  1B3D A;  3B92 A;  1BKC I;  3TS4 A;  4IN9 A;  1PWP A;  3HDA P;  1BKC A;  1XUR A;  1I73 A;  4WZV A;  2OXW A;  5I12 A;  1Z3J A;  1KAP P;  1ROS A;  4GWN A;  5D1U A;  5L79 A;  3DNG A;  2K9C A;  4I35 A;  4QKZ A;  1SU3 A;  3F18 A;  2JNP A;  3DTE A;  3LGP A;  4WK7 A;  5CZM A;  5D1T A;  2XS4 A;  4A7B A;  5D1S A;  3HY9 A;  3EDZ A;  4L7A A;  1AST A;  2YIG A;  1G49 A;  2OXU A;  4G0D A;  1HOV A;  1CAQ A;  1G4K A;  5I43 A;  3Q2G A;  1RMZ A;  3DPF A;  1Y0V A;  1OS2 A;  3N2V A;  3KWV C;  2Z2D A;  3NX7 A;  2DDY A;  4WF6 A;  4GF1 A;  3F17 A;  1JAN A;  3MA2 A;  3O2X A;  1DTH A;  1BQO A;  2OVX A;  3OHL A;  1XUC A;  2FV5 A;  1YOU A;  4XM7 A;  3LJT A;  1UTT A;  2A8H A;  1IAB A;  1C7K A;  4CTH A;  4ZR5 A;  3VTG A;  1SLN A;  3LMC A;  3EDG A;  5H8X A;  4L6T A;  3DTI A;  3HBU P;  2W15 A;  3F16 A;  4XM6 A;  2L0R A;  3Q2H A;  2W13 A;  4G9L A;  2TCL A;  1R54 A;  3K7N A;  1HTD A;  1OM7 A;  2W12 A;  1G05 A;  1A86 A;  3ELM A;  3I7I A;  4AXQ A;  2OW0 A;  1SAT A;  1XFX A;  1USN A;  3USN A;  5CXA A;  4L63 A;  3DL1 A;  3L0V A;  4PKT A;  2Y6D A;  4H2E A;  2KRJ A;  4FXQ A;  2ERO A;  830C A;  1GO8 P;  1JH1 A;  1IAE A;  1D7X A;  2J0T A;  3ZXH A;  1UMS A;  1BIW A;  1EB6 A;  2DW1 A;  1GE5 A;  3LQB A;  1FM1 A;  5I4O A;  2YUF A;  4FU4 A;  5B5P A;  1OMJ A;  5CUH A;  3TT4 A;  2OW1 A;  4ON1 A;  1JJ9 A;  1B8Y A;  4XBH A;  2WOA A;  3VI1 A;  2ERQ A;  1R55 A;  3TVC A;  1XFZ A;  1CQR A;  1ND1 A;  1JIZ A;  4L19 A;  3BA0 A;  1BM6 A;  4XCT A;  2CKI A;  2OVZ A;  4H1Q A;  1IAD A;  1ZP5 A;  2JSD A;  5LAB A;  1KBC A;  1QIA A;  1XFU A;  1PWV A;  1EUB A;  456C A;  4GR0 A;  2DW2 A;  3P24 A;  1GE7 A;  2OZR A;  2RJQ A;  3WV2 A;  1MMR A;  3B2Z A;  1YCM A;  1ZVX A;  1OS9 A;  1I76 A;  1QJI A;  4I03 A;  3KME A;  3WV1 A;  3AYU A;  1MMP A;  3EWJ A;  2POJ A;  1CGF A;  4PKR A;  2WO8 A;  1CK7 A;  2W14 A;  2JT5 A;  2MZI A;  3KMC A;  4PKW A;  1HFC A;  2JT6 A;  2MLS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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