3L0TA

Crystal structure of catalytic domain of tace with hydantoin inhibitor
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
257
structure length
254
Chain Sequence
PDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYGGSPSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery and SAR of hydantoin TACE inhibitors.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Disintegrin and metalloproteinase domain-containing protein
total genus 81
structure length 254
sequence length 257
chains with identical sequence B
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2009-12-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3l0tA00
2MLRA 1CIZA 3O2XA 2E2DA 1JJ9A 3ELMA 4IUWA 1QICA 2K9CA 1MMRA 3VI1A 1QUAA 1JIZA 1HFCA 1A86A 2HU6A 5H8XA 5L79A 4XM8A 5L7FA 3O64A 4G9LA 3BA0A 1G49A 5I12A 2X3BA 1QJJA 4XM6A 4PKTA 4PKQA 2ERQA 2MZHA 456CA 1RMZA 4L19A 1C7KA 1QIAA 3LQ0A 1XFWA 1DTHA 3EHYA 4GR0A 3GBOA 1QIBA 1ZXVA 1D5JA 1OM7A 1K7QA 4R3VA 1CQRA 1GE7A 3HDAP 4DF9A 4WKEA 1C3IA 4H30A 2E3XA 1GKDA 4WZVA 4FXQA 1HY7A 1OS9A 3E8RA 3K7LA 3HY7A 3EDZA 4XBHA 1ATLA 3I7GA 1YP1A 1K7GA 1UEAA 3TT4A 5I3MA 1GKCA 2Y6DA 2K2GA 3LJTA 1RM8A 1HOVA 2OI0A 2FV9A 1Y8JA 3Q2GA 3DPFA 3N2UA 4AYKA 5BPAA 1BKCA 1FM1A 4H3XA 4GR8A 3KECA 4DD8A 3ZXHA 1XUDA 5B5PA 3KWVC 2OVZA 2I47A 1CAQA 1G05A 3EDHA 1MMPA 3ZUKA 1PWVA 4H82A 2PJTA 4HX3A 5LABA 4PKWA 5D1SA 2XS3A 1JANA 1EB6A 2DW2A 1JKYA 1CGLA 1IADA 1FBLA 3P24A 2MLSA 2N8RA 2OXZA 1ND1A 1BQQM 1H71P 1BUDA 1R55A 1B8YA 1G4KA 1IABA 1BUVM 4WF6A 3L0TA 2AIGP 2DDYA 4CTHA 2W12A 4GF1A 4HMAA 4JA1A 1IAAA 1PWWA 1XURA 4AXQA 1Y93A 4Q1LA 2D1NA 3LJZA 1I1IP 2OVXA 1XFVA 2JNPA 4H76A 4JQGA 4GQLA 1ZXCA 4I03A 1XFZA 1A85A 5CUHA 5D7WA 2V4BA 3LUNA 3LUMA 4IJOA 3G42A 1CGFA 4JP4A 3LGPA 3LJGA 5D1TA 3B2ZA 1B3DA 1UTTA 1JH1A 1BKCI 2KRJA 2POJA 1D8MA 2OW0A 1C8TA 3DSLA 4XCTA 4AUOA 1KBCA 1ZTQA 3KMEA 1KUGA 4FU4A 1OS2A 4JPAA 3SHIA 3U1RA 3LE9A 4H1QA 1I76A 1GO8P 2EROA 1MMBA 1CXVA 1GO7P 4XM7A 5I43A 5CXAA 3RTSA 2D1OA 1MMQA 4FVLA 3EWJA 1BM6A 5B5OA 2YB9A 4WKIA 3DPEA 1I73A 1L6JA 4PKRA 2DW0A 1UMTA 4ON1A 3WV3A 2DW1A 3KMCA 3AIGA 4L6TA 1R54A 1ZP5A 1SATA 2TCLA 1IACA 4DV8A 3LEAA 1GXDA 4FXYP 2CLTA 2JT5A 2RJQA 1HTDA 3K7NA 3CKIA 2OW9A 1D7XA 4GR3A 1AYKA 2WO8A 1GE5A 2OY4A 1G9KA 2OXUA 1SLMA 4H2EA 1O0QA 2O36A 2OY2A 1Q3AA 5D3CA 1DMTA 1IAEA 3EHXA 3WV1A 1JAOA 1AF0A 2JSDA 1KUIA 3HBVP 2RJPA 3HY9A 2L0RA 1MNCA 1KUFA 4AIGA 1YQYA 1CK7A 1J7NA 2Z2DA 3B92A 3RTTA 1ROSA 2ERPA 2USNA 4WK7A 3V96B 1YOUA 1S4BP 3KRYA 3F16A 2W13A 3LIRA 2W0DA 3UVCA 3P1VA 1PWPA 3WV2A 3KHIA 4I35A 4GWNA 3L0VA 1BZSA 1ZVXA 1PWQA 2CKIA 2FV5A 1EUBA 3EDGA 4H49A 3LKAA 2J83A 3VTGA 1D8FA 3KEJA 1OO9A 1AKLA 1SLNA 1BKCE 3HDBA 1SMPA 1ZS0A 3F1AA 2QPJA 3KEKA 4GWMA 1JK3A 4JIJA 2XS4A 1PWUA 1EAKA 2WOAA 1BIWA 1O0TA 1R1IA 1BSWA 3HBUP 1XFUA 1Y0VA 4G0DA 2MZEA 3F18A 2WO9A 1KAPP 1XFYA 4A7BA 2W15A 5D2BA 1WNIA 1R1JA 5BOTA 5D1UA 2OW2A 3LMCA 2O3EA 5I0LA 1JIWP 2A8HA 3HYGA 3OHOA 4ILWD 1Z3JA 3B8ZA 2X3AA 2OW1A 1GE6A 1JAPA 3DWBA 2W14A 1HFSA 1JAQA 5I4OA 1OM8A 4GUYA 4PKVA 1HV5A 1OM6A 1SU3A 1YCMA 2X7MA 3MA2A 2AYKA 1IAGA 3ZVSA 1XFXA 2J0TA 3N2VA 1QJIA 1ASTA 2JIHA 4L63A 1K7IA 3AYUA 2SRTA 830CA 1G12A 4EFSA 2OXWA 3USNA 4IN9A 1R1HA 3F17A 3AYKA 1BQOA 1KUHA 3TSKA 3NX7A 4DPEA 3TS4A 3F15A 4H84A 1KUKA 3Q2HA 5JMYA 3DL1A 3DNGA 5CZMA 3LILA 4A3WA 1UMSA 1FLSA 3EDIA 3OHLA 4PKSA 2JT6A 1OMJA 3LQBA 1SRPA 3G5CA 2DDFA 3HB2P 4J4MA 1CGEA 5I2ZA 3I7IA 1XUCA 2Y6CA 3F19A 3LK8A 2X3CA 966CA 2MZIA 4ZR5A 1UTZA 4PKUA 1USNA 3LIKA 2OZRA 4QKZA 3TVCA 2YIGA 5BOYA
chains in the Genus database with same CATH superfamily
2MLRA 1CIZA 3O2XA 2E2DA 1JJ9A 3ELMA 4IUWA 1QICA 2K9CA 1MMRA 3VI1A 1QUAA 1OZ9A 1JIZA 1HFCA 1A86A 2HU6A 5H8XA 5L79A 4XM8A 5L7FA 3O64A 4G9LA 3BA0A 1G49A 5I12A 2X3BA 1QJJA 4XM6A 4PKTA 4PKQA 2ERQA 2MZHA 456CA 1RMZA 4L19A 1C7KA 1QIAA 3LQ0A 1XFWA 1TVIA 1DTHA 3EHYA 4GR0A 3GBOA 1QIBA 1ZXVA 1D5JA 1OM7A 1K7QA 4R3VA 1CQRA 1GE7A 3HDAP 4DF9A 4WKEA 1C3IA 4H30A 2E3XA 1GKDA 4WZVA 4FXQA 1HY7A 1OS9A 3E8RA 3K7LA 3HY7A 3EDZA 4XBHA 1ATLA 3I7GA 1YP1A 1K7GA 1UEAA 3TT4A 5I3MA 1GKCA 2Y6DA 2K2GA 3LJTA 1RM8A 1HOVA 2OI0A 2FV9A 1Y8JA 3Q2GA 3DPFA 3N2UA 3DTIA 4AYKA 1XM5A 5BPAA 1BKCA 1FM1A 4H3XA 4GR8A 3KECA 4DD8A 3ZXHA 1XUDA 5B5PA 3KWVC 2OVZA 2I47A 1CAQA 1G05A 3EDHA 1MMPA 3ZUKA 1PWVA 4H82A 2PJTA 4HX3A 5LABA 4PKWA 5D1SA 2XS3A 1JANA 1EB6A 2DW2A 1JKYA 1CGLA 1IADA 1FBLA 3P24A 2MLSA 2N8RA 2OXZA 1ND1A 3DTEA 1BQQM 1H71P 1BUDA 1R55A 1B8YA 1G4KA 1IABA 1BUVM 4WF6A 3L0TA 2AIGP 2DDYA 4CTHA 2W12A 4GF1A 4HMAA 4JA1A 2YUFA 1IAAA 1PWWA 1XURA 4AXQA 1Y93A 4Q1LA 2D1NA 3LJZA 1I1IP 2OVXA 1XFVA 2JNPA 4H76A 4JQGA 4GQLA 1ZXCA 4I03A 1XFZA 1A85A 5CUHA 5D7WA 2V4BA 3LUNA 3LUMA 4IJOA 3G42A 1CGFA 4JP4A 3LGPA 3LJGA 5D1TA 3B2ZA 1B3DA 1UTTA 1JH1A 1BKCI 2KRJA 2POJA 1D8MA 2OW0A 1C8TA 3DSLA 4XCTA 4AUOA 1KBCA 1ZTQA 3KMEA 1KUGA 4FU4A 1OS2A 4JPAA 3SHIA 3U1RA 3LE9A 4H1QA 1I76A 1GO8P 2EROA 1MMBA 1CXVA 1GO7P 4XM7A 5I43A 5CXAA 3RTSA 2D1OA 1MMQA 4FVLA 3EWJA 1BM6A 5B5OA 2YB9A 4WKIA 3DPEA 1I73A 1L6JA 4PKRA 2DW0A 1UMTA 4ON1A 3WV3A 2DW1A 3KMCA 3AIGA 4L6TA 1R54A 1ZP5A 1SATA 2TCLA 1IACA 4DV8A 3LEAA 1GXDA 4FXYP 2CLTA 2JT5A 2RJQA 1HTDA 3K7NA 3CKIA 2OW9A 1D7XA 4GR3A 1AYKA 2WO8A 1GE5A 2OY4A 1G9KA 2OXUA 1SLMA 4H2EA 1O0QA 2O36A 2OY2A 1Q3AA 5D3CA 1DMTA 1IAEA 1XAXA 3EHXA 3WV1A 1JAOA 1AF0A 2JSDA 1KUIA 3HBVP 2RJPA 3HY9A 2L0RA 1MNCA 1KUFA 4AIGA 1YQYA 1CK7A 1J7NA 2Z2DA 3B92A 3RTTA 1ROSA 2ERPA 2USNA 4WK7A 3V96B 1YOUA 1S4BP 3KRYA 3F16A 2W13A 3LIRA 2W0DA 3UVCA 3P1VA 1PWPA 3WV2A 3KHIA 4I35A 4GWNA 3L0VA 1BZSA 1ZVXA 1PWQA 2CKIA 2FV5A 1EUBA 3EDGA 4H49A 3LKAA 2J83A 3VTGA 1D8FA 3KEJA 1OO9A 1AKLA 1SLNA 1BKCE 3HDBA 1SMPA 1ZS0A 3F1AA 2QPJA 3KEKA 4GWMA 1JK3A 4JIJA 2XS4A 1PWUA 1EAKA 2WOAA 1BIWA 1O0TA 1R1IA 1BSWA 3HBUP 1XFUA 1Y0VA 4G0DA 2MZEA 3F18A 2WO9A 1KAPP 1XFYA 4A7BA 2W15A 5D2BA 1WNIA 1R1JA 5BOTA 5D1UA 2OW2A 3LMCA 3DTKA 2O3EA 5I0LA 1JIWP 2A8HA 3HYGA 3OHOA 4ILWD 1Z3JA 3B8ZA 2X3AA 2OW1A 1GE6A 1JAPA 3DWBA 2W14A 1HFSA 1JAQA 5I4OA 1OM8A 4GUYA 4PKVA 1HV5A 1OM6A 1SU3A 1YCMA 2X7MA 3MA2A 2AYKA 1IAGA 3ZVSA 1XFXA 2J0TA 3N2VA 1QJIA 1ASTA 2JIHA 4L63A 1K7IA 3AYUA 2SRTA 830CA 1G12A 4EFSA 2OXWA 3USNA 4IN9A 1R1HA 3F17A 3AYKA 1BQOA 4L7AA 1KUHA 3TSKA 3NX7A 4DPEA 3TS4A 3F15A 4H84A 1KUKA 3Q2HA 5JMYA 3DL1A 3DNGA 5CZMA 3LILA 4A3WA 1UMSA 1FLSA 3EDIA 3OHLA 4PKSA 2JT6A 1OMJA 3LQBA 1SRPA 3G5CA 2DDFA 3HB2P 4J4MA 1CGEA 5I2ZA 3I7IA 1XUCA 2Y6CA 3F19A 3LK8A 2X3CA 966CA 2MZIA 4ZR5A 1UTZA 4PKUA 1USNA 3LIKA 2OZRA 4QKZA 3TVCA 2YIGA 5BOYA
chains in the Genus database with same CATH topology
2MLRA 1CIZA 3O2XA 2E2DA 1JJ9A 3ELMA 4IUWA 1QICA 2K9CA 1MMRA 3VI1A 1QUAA 1JIZA 1HFCA 1A86A 2HU6A 5H8XA 5L79A 4XM8A 5L7FA 3O64A 4G9LA 3BA0A 1G49A 5I12A 2X3BA 1QJJA 4XM6A 4PKTA 4PKQA 2ERQA 2MZHA 456CA 1RMZA 4L19A 1C7KA 1QIAA 3LQ0A 1XFWA 1DTHA 3EHYA 4GR0A 3GBOA 1QIBA 1ZXVA 1D5JA 1OM7A 1K7QA 4R3VA 1CQRA 1GE7A 3HDAP 4DF9A 4WKEA 1C3IA 4H30A 2E3XA 1GKDA 4WZVA 4FXQA 1HY7A 1OS9A 3E8RA 3K7LA 3HY7A 3EDZA 4XBHA 1ATLA 3I7GA 1YP1A 1K7GA 1UEAA 3TT4A 5I3MA 1GKCA 2Y6DA 2K2GA 3LJTA 1RM8A 1HOVA 2OI0A 2FV9A 1Y8JA 3Q2GA 3DPFA 3N2UA 3DTIA 4AYKA 5BPAA 1BKCA 1FM1A 4H3XA 4GR8A 3KECA 4DD8A 3ZXHA 1XUDA 5B5PA 3KWVC 2OVZA 2I47A 1CAQA 1G05A 3EDHA 1MMPA 3ZUKA 1PWVA 4H82A 2PJTA 4HX3A 5LABA 4PKWA 5D1SA 2XS3A 1JANA 1EB6A 2DW2A 1JKYA 1CGLA 1IADA 1FBLA 3P24A 2MLSA 2N8RA 2OXZA 1ND1A 3DTEA 1BQQM 1H71P 1BUDA 1R55A 1B8YA 1G4KA 1IABA 1BUVM 4WF6A 3L0TA 2AIGP 2DDYA 4CTHA 2W12A 4GF1A 4HMAA 4JA1A 2YUFA 1IAAA 1PWWA 1XURA 4AXQA 1Y93A 4Q1LA 2D1NA 3LJZA 1I1IP 2OVXA 1XFVA 2JNPA 4H76A 4JQGA 4GQLA 1ZXCA 4I03A 1XFZA 1A85A 5CUHA 5D7WA 2V4BA 3LUNA 3LUMA 4IJOA 3G42A 1CGFA 4JP4A 3LGPA 3LJGA 5D1TA 3B2ZA 1B3DA 1UTTA 1JH1A 1BKCI 2KRJA 2POJA 1D8MA 2OW0A 1C8TA 3DSLA 4XCTA 4AUOA 1KBCA 1ZTQA 3KMEA 1KUGA 4FU4A 1OS2A 4JPAA 3SHIA 3U1RA 3LE9A 4H1QA 1I76A 1GO8P 2EROA 1MMBA 1CXVA 1GO7P 4XM7A 5I43A 5CXAA 3RTSA 2D1OA 1MMQA 4FVLA 3EWJA 1BM6A 5B5OA 2YB9A 4WKIA 3DPEA 1I73A 1L6JA 4PKRA 2DW0A 1UMTA 4ON1A 3WV3A 2DW1A 3KMCA 3AIGA 4L6TA 1R54A 1ZP5A 1SATA 2TCLA 1IACA 4DV8A 3LEAA 1GXDA 4FXYP 2CLTA 2JT5A 2RJQA 1HTDA 3K7NA 3CKIA 2OW9A 1D7XA 4GR3A 1AYKA 2WO8A 1GE5A 2OY4A 1G9KA 2OXUA 1SLMA 4H2EA 1O0QA 2O36A 2OY2A 1Q3AA 5D3CA 1DMTA 1IAEA 3EHXA 3WV1A 1JAOA 1AF0A 2JSDA 1KUIA 3HBVP 2RJPA 3HY9A 2L0RA 1MNCA 1KUFA 4AIGA 1YQYA 1CK7A 1J7NA 2Z2DA 3B92A 3RTTA 1ROSA 2ERPA 2USNA 4WK7A 3V96B 1YOUA 1S4BP 3KRYA 3F16A 2W13A 3LIRA 2W0DA 3UVCA 3P1VA 1PWPA 3WV2A 3KHIA 4I35A 4GWNA 3L0VA 1BZSA 1ZVXA 1PWQA 2CKIA 2FV5A 1EUBA 3EDGA 4H49A 3LKAA 2J83A 3VTGA 1D8FA 3KEJA 1OO9A 1AKLA 1SLNA 1BKCE 3HDBA 1SMPA 1ZS0A 3F1AA 2QPJA 3KEKA 4GWMA 1JK3A 4JIJA 2XS4A 1PWUA 1EAKA 2WOAA 1BIWA 1O0TA 1R1IA 1BSWA 3HBUP 1XFUA 1Y0VA 4G0DA 2MZEA 3F18A 2WO9A 1KAPP 1XFYA 4A7BA 2W15A 5D2BA 1WNIA 1R1JA 5BOTA 5D1UA 2OW2A 3LMCA 3DTKA 2O3EA 5I0LA 1JIWP 2A8HA 3HYGA 3OHOA 4ILWD 1Z3JA 3B8ZA 2X3AA 2OW1A 1GE6A 1JAPA 3DWBA 2W14A 1HFSA 1JAQA 5I4OA 1OM8A 4GUYA 4PKVA 1HV5A 1OM6A 1SU3A 1YCMA 2X7MA 3MA2A 2AYKA 1IAGA 3ZVSA 1XFXA 2J0TA 3N2VA 1QJIA 1ASTA 2JIHA 4L63A 1K7IA 3AYUA 2SRTA 830CA 1G12A 4EFSA 2OXWA 3USNA 4IN9A 1R1HA 3F17A 3AYKA 1BQOA 4L7AA 1KUHA 3TSKA 3NX7A 4DPEA 3TS4A 3F15A 4H84A 1KUKA 3Q2HA 5JMYA 3DL1A 3DNGA 5CZMA 3LILA 4A3WA 1UMSA 1FLSA 3EDIA 3OHLA 4PKSA 2JT6A 1OMJA 3LQBA 1SRPA 3G5CA 2DDFA 3HB2P 4J4MA 1CGEA 5I2ZA 3I7IA 1XUCA 2Y6CA 3F19A 3LK8A 2X3CA 966CA 2MZIA 4ZR5A 1UTZA 4PKUA 1USNA 3LIKA 2OZRA 4QKZA 3TVCA 2YIGA 5BOYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2MLR A;  1CIZ A;  3O2X A;  2E2D A;  1JJ9 A;  3ELM A;  4IUW A;  1QIC A;  2K9C A;  1MMR A;  3VI1 A;  1QUA A;  1JIZ A;  1HFC A;  1A86 A;  2HU6 A;  5H8X A;  5L79 A;  4XM8 A;  5L7F A;  3O64 A;  4G9L A;  3BA0 A;  1G49 A;  5I12 A;  2X3B A;  1QJJ A;  4XM6 A;  4PKT A;  4PKQ A;  2ERQ A;  2MZH A;  456C A;  1RMZ A;  4L19 A;  1C7K A;  1QIA A;  3LQ0 A;  1XFW A;  1DTH A;  3EHY A;  4GR0 A;  3GBO A;  1QIB A;  1ZXV A;  1D5J A;  1OM7 A;  1K7Q A;  4R3V A;  1CQR A;  1GE7 A;  3HDA P;  4DF9 A;  4WKE A;  1C3I A;  4H30 A;  2E3X A;  1GKD A;  4WZV A;  4FXQ A;  1HY7 A;  1OS9 A;  3E8R A;  3K7L A;  3HY7 A;  3EDZ A;  4XBH A;  1ATL A;  3I7G A;  1YP1 A;  1K7G A;  1UEA A;  3TT4 A;  5I3M A;  1GKC A;  2Y6D A;  2K2G A;  3LJT A;  1RM8 A;  1HOV A;  2OI0 A;  2FV9 A;  1Y8J A;  3Q2G A;  3DPF A;  3N2U A;  4AYK A;  5BPA A;  1BKC A;  1FM1 A;  4H3X A;  4GR8 A;  3KEC A;  4DD8 A;  3ZXH A;  1XUD A;  5B5P A;  3KWV C;  2OVZ A;  2I47 A;  1CAQ A;  1G05 A;  3EDH A;  1MMP A;  3ZUK A;  1PWV A;  4H82 A;  2PJT A;  4HX3 A;  5LAB A;  4PKW A;  5D1S A;  2XS3 A;  1JAN A;  1EB6 A;  2DW2 A;  1JKY A;  1CGL A;  1IAD A;  1FBL A;  3P24 A;  2MLS A;  2N8R A;  2OXZ A;  1ND1 A;  1BQQ M;  1H71 P;  1BUD A;  1R55 A;  1B8Y A;  1G4K A;  1IAB A;  1BUV M;  4WF6 A;  3L0T A;  2AIG P;  2DDY A;  4CTH A;  2W12 A;  4GF1 A;  4HMA A;  4JA1 A;  1IAA A;  1PWW A;  1XUR A;  4AXQ A;  1Y93 A;  4Q1L A;  2D1N A;  3LJZ A;  1I1I P;  2OVX A;  1XFV A;  2JNP A;  4H76 A;  4JQG A;  4GQL A;  1ZXC A;  4I03 A;  1XFZ A;  1A85 A;  5CUH A;  5D7W A;  2V4B A;  3LUN A;  3LUM A;  4IJO A;  3G42 A;  1CGF A;  4JP4 A;  3LGP A;  3LJG A;  5D1T A;  3B2Z A;  1B3D A;  1UTT A;  1JH1 A;  1BKC I;  2KRJ A;  2POJ A;  1D8M A;  2OW0 A;  1C8T A;  3DSL A;  4XCT A;  4AUO A;  1KBC A;  1ZTQ A;  3KME A;  1KUG A;  4FU4 A;  1OS2 A;  4JPA A;  3SHI A;  3U1R A;  3LE9 A;  4H1Q A;  1I76 A;  1GO8 P;  2ERO A;  1MMB A;  1CXV A;  1GO7 P;  4XM7 A;  5I43 A;  5CXA A;  3RTS A;  2D1O A;  1MMQ A;  4FVL A;  3EWJ A;  1BM6 A;  5B5O A;  2YB9 A;  4WKI A;  3DPE A;  1I73 A;  1L6J A;  4PKR A;  2DW0 A;  1UMT A;  4ON1 A;  3WV3 A;  2DW1 A;  3KMC A;  3AIG A;  4L6T A;  1R54 A;  1ZP5 A;  1SAT A;  2TCL A;  1IAC A;  4DV8 A;  3LEA A;  1GXD A;  4FXY P;  2CLT A;  2JT5 A;  2RJQ A;  1HTD A;  3K7N A;  3CKI A;  2OW9 A;  1D7X A;  4GR3 A;  1AYK A;  2WO8 A;  1GE5 A;  2OY4 A;  1G9K A;  2OXU A;  1SLM A;  4H2E A;  1O0Q A;  2O36 A;  2OY2 A;  1Q3A A;  5D3C A;  1DMT A;  1IAE A;  3EHX A;  3WV1 A;  1JAO A;  1AF0 A;  2JSD A;  1KUI A;  3HBV P;  2RJP A;  3HY9 A;  2L0R A;  1MNC A;  1KUF A;  4AIG A;  1YQY A;  1CK7 A;  1J7N A;  2Z2D A;  3B92 A;  3RTT A;  1ROS A;  2ERP A;  2USN A;  4WK7 A;  3V96 B;  1YOU A;  1S4B P;  3KRY A;  3F16 A;  2W13 A;  3LIR A;  2W0D A;  3UVC A;  3P1V A;  1PWP A;  3WV2 A;  3KHI A;  4I35 A;  4GWN A;  3L0V A;  1BZS A;  1ZVX A;  1PWQ A;  2CKI A;  2FV5 A;  1EUB A;  3EDG A;  4H49 A;  3LKA A;  2J83 A;  3VTG A;  1D8F A;  3KEJ A;  1OO9 A;  1AKL A;  1SLN A;  1BKC E;  3HDB A;  1SMP A;  1ZS0 A;  3F1A A;  2QPJ A;  3KEK A;  4GWM A;  1JK3 A;  4JIJ A;  2XS4 A;  1PWU A;  1EAK A;  2WOA A;  1BIW A;  1O0T A;  1R1I A;  1BSW A;  3HBU P;  1XFU A;  1Y0V A;  4G0D A;  2MZE A;  3F18 A;  2WO9 A;  1KAP P;  1XFY A;  4A7B A;  2W15 A;  5D2B A;  1WNI A;  1R1J A;  5BOT A;  5D1U A;  2OW2 A;  3LMC A;  2O3E A;  5I0L A;  1JIW P;  2A8H A;  3HYG A;  3OHO A;  4ILW D;  1Z3J A;  3B8Z A;  2X3A A;  2OW1 A;  1GE6 A;  1JAP A;  3DWB A;  2W14 A;  1HFS A;  1JAQ A;  5I4O A;  1OM8 A;  4GUY A;  4PKV A;  1HV5 A;  1OM6 A;  1SU3 A;  1YCM A;  2X7M A;  3MA2 A;  2AYK A;  1IAG A;  3ZVS A;  1XFX A;  2J0T A;  3N2V A;  1QJI A;  1AST A;  2JIH A;  4L63 A;  1K7I A;  3AYU A;  2SRT A;  830C A;  1G12 A;  4EFS A;  2OXW A;  3USN A;  4IN9 A;  1R1H A;  3F17 A;  3AYK A;  1BQO A;  1KUH A;  3TSK A;  3NX7 A;  4DPE A;  3TS4 A;  3F15 A;  4H84 A;  1KUK A;  3Q2H A;  5JMY A;  3DL1 A;  3DNG A;  5CZM A;  3LIL A;  4A3W A;  1UMS A;  1FLS A;  3EDI A;  3OHL A;  4PKS A;  2JT6 A;  1OMJ A;  3LQB A;  1SRP A;  3G5C A;  2DDF A;  3HB2 P;  4J4M A;  1CGE A;  5I2Z A;  3I7I A;  1XUC A;  2Y6C A;  3F19 A;  3LK8 A;  2X3C A;  966C A;  2MZI A;  4ZR5 A;  1UTZ A;  4PKU A;  1USN A;  3LIK A;  2OZR A;  4QKZ A;  3TVC A;  2YIG A;  5BOY A; 
#chains in the Genus database with same CATH topology
 2MLR A;  1CIZ A;  3O2X A;  2E2D A;  1JJ9 A;  3ELM A;  4IUW A;  1QIC A;  2K9C A;  1MMR A;  3VI1 A;  1QUA A;  1OZ9 A;  1JIZ A;  1HFC A;  1A86 A;  2HU6 A;  5H8X A;  5L79 A;  4XM8 A;  5L7F A;  3O64 A;  4G9L A;  3BA0 A;  1G49 A;  5I12 A;  2X3B A;  1QJJ A;  4XM6 A;  4PKT A;  4PKQ A;  2ERQ A;  2MZH A;  456C A;  1RMZ A;  4L19 A;  1C7K A;  1QIA A;  3LQ0 A;  1XFW A;  1TVI A;  1DTH A;  3EHY A;  4GR0 A;  3GBO A;  1QIB A;  1ZXV A;  1D5J A;  1OM7 A;  1K7Q A;  4R3V A;  1CQR A;  1GE7 A;  3HDA P;  4DF9 A;  4WKE A;  1C3I A;  4H30 A;  2E3X A;  1GKD A;  4WZV A;  4FXQ A;  1HY7 A;  1OS9 A;  3E8R A;  3K7L A;  3HY7 A;  3EDZ A;  4XBH A;  1ATL A;  3I7G A;  1YP1 A;  1K7G A;  1UEA A;  3TT4 A;  5I3M A;  1GKC A;  2Y6D A;  2K2G A;  3LJT A;  1RM8 A;  1HOV A;  2OI0 A;  2FV9 A;  1Y8J A;  3Q2G A;  3DPF A;  3N2U A;  3DTI A;  4AYK A;  1XM5 A;  5BPA A;  1BKC A;  1FM1 A;  4H3X A;  4GR8 A;  3KEC A;  4DD8 A;  3ZXH A;  1XUD A;  5B5P A;  3KWV C;  2OVZ A;  2I47 A;  1CAQ A;  1G05 A;  3EDH A;  1MMP A;  3ZUK A;  1PWV A;  4H82 A;  2PJT A;  4HX3 A;  5LAB A;  4PKW A;  5D1S A;  2XS3 A;  1JAN A;  1EB6 A;  2DW2 A;  1JKY A;  1CGL A;  1IAD A;  1FBL A;  3P24 A;  2MLS A;  2N8R A;  2OXZ A;  1ND1 A;  3DTE A;  1BQQ M;  1H71 P;  1BUD A;  1R55 A;  1B8Y A;  1G4K A;  1IAB A;  1BUV M;  4WF6 A;  3L0T A;  2AIG P;  2DDY A;  4CTH A;  2W12 A;  4GF1 A;  4HMA A;  4JA1 A;  2YUF A;  1IAA A;  1PWW A;  1XUR A;  4AXQ A;  1Y93 A;  4Q1L A;  2D1N A;  3LJZ A;  1I1I P;  2OVX A;  1XFV A;  2JNP A;  4H76 A;  4JQG A;  4GQL A;  1ZXC A;  4I03 A;  1XFZ A;  1A85 A;  5CUH A;  5D7W A;  2V4B A;  3LUN A;  3LUM A;  4IJO A;  3G42 A;  1CGF A;  4JP4 A;  3LGP A;  3LJG A;  5D1T A;  3B2Z A;  1B3D A;  1UTT A;  1JH1 A;  1BKC I;  2KRJ A;  2POJ A;  1D8M A;  2OW0 A;  1C8T A;  3DSL A;  4XCT A;  4AUO A;  1KBC A;  1ZTQ A;  3KME A;  1KUG A;  4FU4 A;  1OS2 A;  4JPA A;  3SHI A;  3U1R A;  3LE9 A;  4H1Q A;  1I76 A;  1GO8 P;  2ERO A;  1MMB A;  1CXV A;  1GO7 P;  4XM7 A;  5I43 A;  5CXA A;  3RTS A;  2D1O A;  1MMQ A;  4FVL A;  3EWJ A;  1BM6 A;  5B5O A;  2YB9 A;  4WKI A;  3DPE A;  1I73 A;  1L6J A;  4PKR A;  2DW0 A;  1UMT A;  4ON1 A;  3WV3 A;  2DW1 A;  3KMC A;  3AIG A;  4L6T A;  1R54 A;  1ZP5 A;  1SAT A;  2TCL A;  1IAC A;  4DV8 A;  3LEA A;  1GXD A;  4FXY P;  2CLT A;  2JT5 A;  2RJQ A;  1HTD A;  3K7N A;  3CKI A;  2OW9 A;  1D7X A;  4GR3 A;  1AYK A;  2WO8 A;  1GE5 A;  2OY4 A;  1G9K A;  2OXU A;  1SLM A;  4H2E A;  1O0Q A;  2O36 A;  2OY2 A;  1Q3A A;  5D3C A;  1DMT A;  1IAE A;  1XAX A;  3EHX A;  3WV1 A;  1JAO A;  1AF0 A;  2JSD A;  1KUI A;  3HBV P;  2RJP A;  3HY9 A;  2L0R A;  1MNC A;  1KUF A;  4AIG A;  1YQY A;  1CK7 A;  1J7N A;  2Z2D A;  3B92 A;  3RTT A;  1ROS A;  2ERP A;  2USN A;  4WK7 A;  3V96 B;  1YOU A;  1S4B P;  3KRY A;  3F16 A;  2W13 A;  3LIR A;  2W0D A;  3UVC A;  3P1V A;  1PWP A;  3WV2 A;  3KHI A;  4I35 A;  4GWN A;  3L0V A;  1BZS A;  1ZVX A;  1PWQ A;  2CKI A;  2FV5 A;  1EUB A;  3EDG A;  4H49 A;  3LKA A;  2J83 A;  3VTG A;  1D8F A;  3KEJ A;  1OO9 A;  1AKL A;  1SLN A;  1BKC E;  3HDB A;  1SMP A;  1ZS0 A;  3F1A A;  2QPJ A;  3KEK A;  4GWM A;  1JK3 A;  4JIJ A;  2XS4 A;  1PWU A;  1EAK A;  2WOA A;  1BIW A;  1O0T A;  1R1I A;  1BSW A;  3HBU P;  1XFU A;  1Y0V A;  4G0D A;  2MZE A;  3F18 A;  2WO9 A;  1KAP P;  1XFY A;  4A7B A;  2W15 A;  5D2B A;  1WNI A;  1R1J A;  5BOT A;  5D1U A;  2OW2 A;  3LMC A;  3DTK A;  2O3E A;  5I0L A;  1JIW P;  2A8H A;  3HYG A;  3OHO A;  4ILW D;  1Z3J A;  3B8Z A;  2X3A A;  2OW1 A;  1GE6 A;  1JAP A;  3DWB A;  2W14 A;  1HFS A;  1JAQ A;  5I4O A;  1OM8 A;  4GUY A;  4PKV A;  1HV5 A;  1OM6 A;  1SU3 A;  1YCM A;  2X7M A;  3MA2 A;  2AYK A;  1IAG A;  3ZVS A;  1XFX A;  2J0T A;  3N2V A;  1QJI A;  1AST A;  2JIH A;  4L63 A;  1K7I A;  3AYU A;  2SRT A;  830C A;  1G12 A;  4EFS A;  2OXW A;  3USN A;  4IN9 A;  1R1H A;  3F17 A;  3AYK A;  1BQO A;  4L7A A;  1KUH A;  3TSK A;  3NX7 A;  4DPE A;  3TS4 A;  3F15 A;  4H84 A;  1KUK A;  3Q2H A;  5JMY A;  3DL1 A;  3DNG A;  5CZM A;  3LIL A;  4A3W A;  1UMS A;  1FLS A;  3EDI A;  3OHL A;  4PKS A;  2JT6 A;  1OMJ A;  3LQB A;  1SRP A;  3G5C A;  2DDF A;  3HB2 P;  4J4M A;  1CGE A;  5I2Z A;  3I7I A;  1XUC A;  2Y6C A;  3F19 A;  3LK8 A;  2X3C A;  966C A;  2MZI A;  4ZR5 A;  1UTZ A;  4PKU A;  1USN A;  3LIK A;  2OZR A;  4QKZ A;  3TVC A;  2YIG A;  5BOY A; 
#chains in the Genus database with same CATH homology
 2MLR A;  1CIZ A;  3O2X A;  2E2D A;  1JJ9 A;  3ELM A;  4IUW A;  1QIC A;  2K9C A;  1MMR A;  3VI1 A;  1QUA A;  1JIZ A;  1HFC A;  1A86 A;  2HU6 A;  5H8X A;  5L79 A;  4XM8 A;  5L7F A;  3O64 A;  4G9L A;  3BA0 A;  1G49 A;  5I12 A;  2X3B A;  1QJJ A;  4XM6 A;  4PKT A;  4PKQ A;  2ERQ A;  2MZH A;  456C A;  1RMZ A;  4L19 A;  1C7K A;  1QIA A;  3LQ0 A;  1XFW A;  1DTH A;  3EHY A;  4GR0 A;  3GBO A;  1QIB A;  1ZXV A;  1D5J A;  1OM7 A;  1K7Q A;  4R3V A;  1CQR A;  1GE7 A;  3HDA P;  4DF9 A;  4WKE A;  1C3I A;  4H30 A;  2E3X A;  1GKD A;  4WZV A;  4FXQ A;  1HY7 A;  1OS9 A;  3E8R A;  3K7L A;  3HY7 A;  3EDZ A;  4XBH A;  1ATL A;  3I7G A;  1YP1 A;  1K7G A;  1UEA A;  3TT4 A;  5I3M A;  1GKC A;  2Y6D A;  2K2G A;  3LJT A;  1RM8 A;  1HOV A;  2OI0 A;  2FV9 A;  1Y8J A;  3Q2G A;  3DPF A;  3N2U A;  3DTI A;  4AYK A;  5BPA A;  1BKC A;  1FM1 A;  4H3X A;  4GR8 A;  3KEC A;  4DD8 A;  3ZXH A;  1XUD A;  5B5P A;  3KWV C;  2OVZ A;  2I47 A;  1CAQ A;  1G05 A;  3EDH A;  1MMP A;  3ZUK A;  1PWV A;  4H82 A;  2PJT A;  4HX3 A;  5LAB A;  4PKW A;  5D1S A;  2XS3 A;  1JAN A;  1EB6 A;  2DW2 A;  1JKY A;  1CGL A;  1IAD A;  1FBL A;  3P24 A;  2MLS A;  2N8R A;  2OXZ A;  1ND1 A;  3DTE A;  1BQQ M;  1H71 P;  1BUD A;  1R55 A;  1B8Y A;  1G4K A;  1IAB A;  1BUV M;  4WF6 A;  3L0T A;  2AIG P;  2DDY A;  4CTH A;  2W12 A;  4GF1 A;  4HMA A;  4JA1 A;  2YUF A;  1IAA A;  1PWW A;  1XUR A;  4AXQ A;  1Y93 A;  4Q1L A;  2D1N A;  3LJZ A;  1I1I P;  2OVX A;  1XFV A;  2JNP A;  4H76 A;  4JQG A;  4GQL A;  1ZXC A;  4I03 A;  1XFZ A;  1A85 A;  5CUH A;  5D7W A;  2V4B A;  3LUN A;  3LUM A;  4IJO A;  3G42 A;  1CGF A;  4JP4 A;  3LGP A;  3LJG A;  5D1T A;  3B2Z A;  1B3D A;  1UTT A;  1JH1 A;  1BKC I;  2KRJ A;  2POJ A;  1D8M A;  2OW0 A;  1C8T A;  3DSL A;  4XCT A;  4AUO A;  1KBC A;  1ZTQ A;  3KME A;  1KUG A;  4FU4 A;  1OS2 A;  4JPA A;  3SHI A;  3U1R A;  3LE9 A;  4H1Q A;  1I76 A;  1GO8 P;  2ERO A;  1MMB A;  1CXV A;  1GO7 P;  4XM7 A;  5I43 A;  5CXA A;  3RTS A;  2D1O A;  1MMQ A;  4FVL A;  3EWJ A;  1BM6 A;  5B5O A;  2YB9 A;  4WKI A;  3DPE A;  1I73 A;  1L6J A;  4PKR A;  2DW0 A;  1UMT A;  4ON1 A;  3WV3 A;  2DW1 A;  3KMC A;  3AIG A;  4L6T A;  1R54 A;  1ZP5 A;  1SAT A;  2TCL A;  1IAC A;  4DV8 A;  3LEA A;  1GXD A;  4FXY P;  2CLT A;  2JT5 A;  2RJQ A;  1HTD A;  3K7N A;  3CKI A;  2OW9 A;  1D7X A;  4GR3 A;  1AYK A;  2WO8 A;  1GE5 A;  2OY4 A;  1G9K A;  2OXU A;  1SLM A;  4H2E A;  1O0Q A;  2O36 A;  2OY2 A;  1Q3A A;  5D3C A;  1DMT A;  1IAE A;  3EHX A;  3WV1 A;  1JAO A;  1AF0 A;  2JSD A;  1KUI A;  3HBV P;  2RJP A;  3HY9 A;  2L0R A;  1MNC A;  1KUF A;  4AIG A;  1YQY A;  1CK7 A;  1J7N A;  2Z2D A;  3B92 A;  3RTT A;  1ROS A;  2ERP A;  2USN A;  4WK7 A;  3V96 B;  1YOU A;  1S4B P;  3KRY A;  3F16 A;  2W13 A;  3LIR A;  2W0D A;  3UVC A;  3P1V A;  1PWP A;  3WV2 A;  3KHI A;  4I35 A;  4GWN A;  3L0V A;  1BZS A;  1ZVX A;  1PWQ A;  2CKI A;  2FV5 A;  1EUB A;  3EDG A;  4H49 A;  3LKA A;  2J83 A;  3VTG A;  1D8F A;  3KEJ A;  1OO9 A;  1AKL A;  1SLN A;  1BKC E;  3HDB A;  1SMP A;  1ZS0 A;  3F1A A;  2QPJ A;  3KEK A;  4GWM A;  1JK3 A;  4JIJ A;  2XS4 A;  1PWU A;  1EAK A;  2WOA A;  1BIW A;  1O0T A;  1R1I A;  1BSW A;  3HBU P;  1XFU A;  1Y0V A;  4G0D A;  2MZE A;  3F18 A;  2WO9 A;  1KAP P;  1XFY A;  4A7B A;  2W15 A;  5D2B A;  1WNI A;  1R1J A;  5BOT A;  5D1U A;  2OW2 A;  3LMC A;  3DTK A;  2O3E A;  5I0L A;  1JIW P;  2A8H A;  3HYG A;  3OHO A;  4ILW D;  1Z3J A;  3B8Z A;  2X3A A;  2OW1 A;  1GE6 A;  1JAP A;  3DWB A;  2W14 A;  1HFS A;  1JAQ A;  5I4O A;  1OM8 A;  4GUY A;  4PKV A;  1HV5 A;  1OM6 A;  1SU3 A;  1YCM A;  2X7M A;  3MA2 A;  2AYK A;  1IAG A;  3ZVS A;  1XFX A;  2J0T A;  3N2V A;  1QJI A;  1AST A;  2JIH A;  4L63 A;  1K7I A;  3AYU A;  2SRT A;  830C A;  1G12 A;  4EFS A;  2OXW A;  3USN A;  4IN9 A;  1R1H A;  3F17 A;  3AYK A;  1BQO A;  4L7A A;  1KUH A;  3TSK A;  3NX7 A;  4DPE A;  3TS4 A;  3F15 A;  4H84 A;  1KUK A;  3Q2H A;  5JMY A;  3DL1 A;  3DNG A;  5CZM A;  3LIL A;  4A3W A;  1UMS A;  1FLS A;  3EDI A;  3OHL A;  4PKS A;  2JT6 A;  1OMJ A;  3LQB A;  1SRP A;  3G5C A;  2DDF A;  3HB2 P;  4J4M A;  1CGE A;  5I2Z A;  3I7I A;  1XUC A;  2Y6C A;  3F19 A;  3LK8 A;  2X3C A;  966C A;  2MZI A;  4ZR5 A;  1UTZ A;  4PKU A;  1USN A;  3LIK A;  2OZR A;  4QKZ A;  3TVC A;  2YIG A;  5BOY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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