3LIKA

Human mmp12 in complex with non-zinc chelating inhibitor
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
159
structure length
159
Chain Sequence
MGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Insights from selective non-phosphinic inhibitors of MMP-12 tailored to fit with an S1' loop canonical conformation.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Macrophage metalloelastase
total genus 44
structure length 159
sequence length 159
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2010-01-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3likA00
1AKLA 1WNIA 2Z2DA 4FU4A 1R1IA 2DW2A 5I0LA 3GBOA 2POJA 1CK7A 2OW1A 4H82A 2WO9A 3NX7A 3EDIA 4G0DA 1B8YA 3HY7A 3HY9A 1SU3A 1QJJA 3F17A 1YP1A 2DDFA 5LABA 4WKEA 2WO8A 1C7KA 2X7MA 3EWJA 3LIKA 2JT6A 1H71P 3F1AA 3N2VA 3LQBA 1K7GA 2KRJA 1JIWP 2J0TA 3L0VA 1GKDA 1ROSA 1G49A 4H1QA 1Q3AA 1JIZA 3P24A 3B2ZA 2W15A 1KUKA 1GE7A 1QUAA 3TSKA 3HB2P 3Q2HA 1KUGA 1UTTA 3F18A 1BUVM 3KWVC 2L0RA 2O3EA 1HTDA 2V4BA 1MMBA 2D1NA 1G9KA 3KEKA 3Q2GA 1IAAA 1EUBA 4GQLA 4H49A 4ILWD 3KECA 1I1IP 3VI1A 2JIHA 1JK3A 1KUIA 3L0TA 1OS2A 5CZMA 3AYUA 3TVCA 2HU6A 3DNGA 2DW1A 3OHOA 3F19A 1HFCA 3LQ0A 4AYKA 1IAGA 1XUCA 2A8HA 4WZVA 1XFUA 2X3CA 1K7IA 1FBLA 1UMSA 3F16A 1Y0VA 1BM6A 1AF0A 4FXQA 4IJOA 2OVXA 3G5CA 2FV5A 1CGFA 3LEAA 2E2DA 2OY2A 4PKWA 3I7GA 1ZS0A 830CA 3TS4A 1PWQA 2D1OA 1CGEA 2W0DA 2X3AA 2RJPA 1CGLA 2MZEA 1K7QA 3LJZA 3WV2A 3O64A 3ZUKA 3LE9A 1BUDA 3HBVP 5L79A 1G4KA 1SATA 4IUWA 2OI0A 3F15A 4ON1A 2OW0A 1R1HA 3E8RA 1ND1A 1OMJA 1UMTA 4H2EA 1OM7A 2OZRA 2Y6CA 4GUYA 1EB6A 1KUFA 1SMPA 4H3XA 4GR8A 2OY4A 4L63A 1ATLA 1IADA 2Y6DA 3EDHA 2K9CA 4JA1A 2EROA 2MLSA 3OHLA 1CXVA 2WOAA 3RTSA 5CUHA 1XFVA 1JAPA 1XFZA 1C8TA 4GWMA 1CIZA 5BPAA 5CXAA 1C3IA 2YB9A 4XCTA 3DPFA 2W12A 2K2GA 1RM8A 3O2XA 4FXYP 1JAOA 2DDYA 4JPAA 3CKIA 4DV8A 4HMAA 3VTGA 5D1UA 3DPEA 1JANA 3I7IA 1PWWA 1BZSA 3U1RA 1ASTA 4QKZA 4FVLA 1D5JA 966CA 4PKTA 1GO8P 5I2ZA 1XUDA 3ELMA 3USNA 3LGPA 4AUOA 1ZP5A 2DW0A 4DD8A 1HY7A 1XFWA 1R54A 4PKRA 1GKCA 2E3XA 2MZHA 4R3VA 2W13A 1JKYA 4GWNA 4JP4A 3DSLA 1BQOA 1GE5A 2PJTA 5B5OA 1JJ9A 4GR3A 1I76A 4ZR5A 2AIGP 3AIGA 4HX3A 2ERPA 1SLMA 2YIGA 1GE6A 4XM7A 3ZVSA 1ZVXA 3LUNA 3LIRA 4XBHA 3K7LA 4WKIA 3LMCA 1S4BP 1GXDA 1IACA 3HDBA 1USNA 1PWPA 3LILA 4DPEA 1I73A 1OS9A 1JH1A 2MLRA 1D8FA 3TT4A 5D1SA 4G9LA 4J4MA 3KMEA 1UTZA 1CQRA 1KBCA 4AIGA 1HV5A 1J7NA 2SRTA 4H76A 4PKUA 1MMPA 2USNA 1IABA 2OXUA 4L6TA 3MA2A 1FM1A 1CAQA 4I35A 3WV3A 5D1TA 1MMRA 4L19A 1YQYA 1ZXVA 3KRYA 1FLSA 3EDZA 3KMCA 3BA0A 1KAPP 1QIBA 4WK7A 1G12A 2O36A 2OW2A 1O0QA 4PKVA 4XM8A 2JNPA 2W14A 1D8MA 2JT5A 1B3DA 1GO7P 3HYGA 456CA 1OM8A 1A85A 3N2UA 2ERQA 5BOTA 1BKCI 1UEAA 1AYKA 2OW9A 5I4OA 1EAKA 4Q1LA 1QJIA 3K7NA 4H84A 5I12A 2J83A 3DL1A 2OVZA 3SHIA 3EHYA 1Z3JA 1OM6A 3RTTA 1R55A 3HBUP 5D3CA 1XFYA 2AYKA 3V96B 4EFSA 1ZXCA 5I43A 1PWUA 1DTHA 1IAEA 1YOUA 1SLNA 4XM6A 2QPJA 3DWBA 1KUHA 4A3WA 1SRPA 1R1JA 4IN9A 3EDGA 2N8RA 4PKQA 4DF9A 2RJQA 2XS3A 1MNCA 5D2BA 3EHXA 1D7XA 4WF6A 1QICA 4JQGA 1BIWA 2TCLA 3KEJA 1YCMA 3B8ZA 5BOYA 3ZXHA 5D7WA 1A86A 2JSDA 1DMTA 2OXZA 3LKAA 3LK8A 1OO9A 5I3MA 1PWVA 3P1VA 5JMYA 1QIAA 2MZIA 1BKCA 1MMQA 4I03A 3B92A 1BSWA 3LJTA 2X3BA 1L6JA 3LJGA 1ZTQA 3WV1A 4H30A 4PKSA 5H8XA 5L7FA 1HOVA 3HDAP 1BQQM 1HFSA 2OXWA 4A7BA 2FV9A 1JAQA 1Y8JA 1RMZA 1BKCE 4CTHA 2XS4A 4JIJA 4GF1A 3AYKA 3KHIA 5B5PA 1Y93A 1XFXA 3LUMA 1G05A 3UVCA 4AXQA 1XURA 2CKIA 4GR0A 2CLTA 3G42A 1O0TA 2I47A
chains in the Genus database with same CATH superfamily
1AKLA 1WNIA 2Z2DA 4FU4A 1R1IA 2DW2A 5I0LA 3GBOA 2POJA 1CK7A 2OW1A 4H82A 2WO9A 3NX7A 3EDIA 4G0DA 1B8YA 3HY7A 3HY9A 1SU3A 1QJJA 3F17A 1YP1A 2DDFA 5LABA 4WKEA 2WO8A 1C7KA 2X7MA 3EWJA 3LIKA 2JT6A 1H71P 3F1AA 3N2VA 3LQBA 1K7GA 2KRJA 1JIWP 2J0TA 3L0VA 1GKDA 1ROSA 1G49A 4H1QA 1Q3AA 1JIZA 3P24A 3B2ZA 2W15A 1KUKA 1GE7A 1QUAA 3TSKA 3HB2P 3Q2HA 1KUGA 1UTTA 3F18A 1BUVM 3KWVC 2L0RA 2O3EA 1HTDA 2V4BA 1MMBA 2D1NA 1G9KA 3KEKA 3Q2GA 1IAAA 1EUBA 4GQLA 4H49A 4ILWD 3KECA 1I1IP 3VI1A 2JIHA 1JK3A 1KUIA 3L0TA 1OS2A 5CZMA 3AYUA 3TVCA 2HU6A 3DNGA 2DW1A 3OHOA 3F19A 1HFCA 3LQ0A 4AYKA 1IAGA 1XUCA 2A8HA 4WZVA 1XFUA 2X3CA 1K7IA 1FBLA 1UMSA 3F16A 1Y0VA 1BM6A 1AF0A 4FXQA 4IJOA 2OVXA 3G5CA 2FV5A 1CGFA 3LEAA 2E2DA 2OY2A 4PKWA 3I7GA 1ZS0A 830CA 3TS4A 1PWQA 2D1OA 1CGEA 2W0DA 2X3AA 2RJPA 1CGLA 2MZEA 1K7QA 3LJZA 3WV2A 3O64A 3ZUKA 1XM5A 3LE9A 1BUDA 3HBVP 5L79A 1G4KA 1SATA 4IUWA 2OI0A 3F15A 4ON1A 2OW0A 1R1HA 3E8RA 1ND1A 1OMJA 1UMTA 4H2EA 1OM7A 2OZRA 2Y6CA 4GUYA 1EB6A 1KUFA 1SMPA 4H3XA 4GR8A 2OY4A 4L63A 1ATLA 1IADA 2Y6DA 3EDHA 2K9CA 4JA1A 2EROA 2MLSA 1OZ9A 3OHLA 1CXVA 2WOAA 3RTSA 5CUHA 1XFVA 1JAPA 1XFZA 1C8TA 4GWMA 1CIZA 5BPAA 5CXAA 1C3IA 2YB9A 4XCTA 3DPFA 2W12A 2K2GA 1RM8A 3O2XA 4FXYP 1JAOA 2DDYA 4JPAA 3CKIA 4DV8A 4HMAA 3VTGA 5D1UA 3DPEA 1JANA 3I7IA 1PWWA 1BZSA 3U1RA 1ASTA 4QKZA 4FVLA 1D5JA 966CA 4PKTA 1GO8P 5I2ZA 1XUDA 3ELMA 3USNA 3LGPA 3DTEA 4AUOA 1ZP5A 2DW0A 4DD8A 1HY7A 1XFWA 1R54A 4PKRA 1GKCA 2E3XA 2MZHA 4R3VA 2W13A 1JKYA 4GWNA 4JP4A 3DSLA 1BQOA 1GE5A 2PJTA 5B5OA 1JJ9A 4GR3A 1I76A 4ZR5A 2AIGP 3AIGA 4HX3A 2ERPA 1SLMA 2YIGA 1GE6A 4XM7A 3ZVSA 1ZVXA 3LUNA 3LIRA 4XBHA 3K7LA 4WKIA 3LMCA 1S4BP 1GXDA 1IACA 3HDBA 1USNA 1PWPA 3LILA 4DPEA 1I73A 1OS9A 1JH1A 2MLRA 1D8FA 3TT4A 2YUFA 5D1SA 4G9LA 4J4MA 3KMEA 1XAXA 3DTKA 1UTZA 1CQRA 1KBCA 4AIGA 1HV5A 1J7NA 2SRTA 4H76A 4PKUA 1MMPA 2USNA 1IABA 2OXUA 4L6TA 3MA2A 1FM1A 1CAQA 4I35A 3WV3A 3DTIA 5D1TA 1MMRA 4L19A 1YQYA 1ZXVA 3KRYA 1FLSA 3EDZA 3KMCA 3BA0A 1KAPP 1QIBA 4WK7A 1G12A 2O36A 2OW2A 1O0QA 4PKVA 4XM8A 2JNPA 2W14A 1D8MA 2JT5A 1B3DA 1GO7P 3HYGA 456CA 1OM8A 1A85A 3N2UA 2ERQA 5BOTA 1BKCI 1UEAA 1AYKA 2OW9A 5I4OA 1EAKA 4Q1LA 4L7AA 1QJIA 3K7NA 4H84A 5I12A 2J83A 3DL1A 2OVZA 3SHIA 3EHYA 1Z3JA 1OM6A 3RTTA 1R55A 3HBUP 5D3CA 1XFYA 2AYKA 3V96B 4EFSA 1ZXCA 5I43A 1PWUA 1DTHA 1IAEA 1YOUA 1SLNA 4XM6A 2QPJA 3DWBA 1KUHA 4A3WA 1SRPA 1R1JA 4IN9A 3EDGA 2N8RA 4PKQA 4DF9A 2RJQA 2XS3A 1MNCA 5D2BA 3EHXA 1D7XA 4WF6A 1QICA 4JQGA 1BIWA 2TCLA 3KEJA 1YCMA 3B8ZA 5BOYA 3ZXHA 5D7WA 1A86A 2JSDA 1DMTA 2OXZA 3LKAA 3LK8A 1OO9A 5I3MA 1PWVA 3P1VA 5JMYA 1QIAA 2MZIA 1BKCA 1MMQA 4I03A 3B92A 1BSWA 3LJTA 2X3BA 1L6JA 3LJGA 1ZTQA 3WV1A 4H30A 4PKSA 5H8XA 5L7FA 1HOVA 1TVIA 3HDAP 1BQQM 1HFSA 2OXWA 4A7BA 2FV9A 1JAQA 1Y8JA 1RMZA 1BKCE 4CTHA 2XS4A 4JIJA 4GF1A 3AYKA 3KHIA 5B5PA 1Y93A 1XFXA 3LUMA 1G05A 3UVCA 4AXQA 1XURA 2CKIA 4GR0A 2CLTA 3G42A 1O0TA 2I47A
chains in the Genus database with same CATH topology
1AKLA 1WNIA 2Z2DA 4FU4A 1R1IA 2DW2A 5I0LA 3GBOA 2POJA 1CK7A 2OW1A 4H82A 2WO9A 3NX7A 3EDIA 4G0DA 1B8YA 3HY7A 3HY9A 1SU3A 1QJJA 3F17A 1YP1A 2DDFA 5LABA 4WKEA 2WO8A 1C7KA 2X7MA 3EWJA 3LIKA 2JT6A 1H71P 3F1AA 3N2VA 3LQBA 1K7GA 2KRJA 1JIWP 2J0TA 3L0VA 1GKDA 1ROSA 1G49A 4H1QA 1Q3AA 1JIZA 3P24A 3B2ZA 2W15A 1KUKA 1GE7A 1QUAA 3TSKA 3HB2P 3Q2HA 1KUGA 1UTTA 3F18A 1BUVM 3KWVC 2L0RA 2O3EA 1HTDA 2V4BA 1MMBA 2D1NA 1G9KA 3KEKA 3Q2GA 1IAAA 1EUBA 4GQLA 4H49A 4ILWD 3KECA 1I1IP 3VI1A 2JIHA 1JK3A 1KUIA 3L0TA 1OS2A 5CZMA 3AYUA 3TVCA 2HU6A 3DNGA 2DW1A 3OHOA 3F19A 1HFCA 3LQ0A 4AYKA 1IAGA 1XUCA 2A8HA 4WZVA 1XFUA 2X3CA 1K7IA 1FBLA 1UMSA 3F16A 1Y0VA 1BM6A 1AF0A 4FXQA 4IJOA 2OVXA 3G5CA 2FV5A 1CGFA 3LEAA 2E2DA 2OY2A 4PKWA 3I7GA 1ZS0A 830CA 3TS4A 1PWQA 2D1OA 1CGEA 2W0DA 2X3AA 2RJPA 1CGLA 2MZEA 1K7QA 3LJZA 3WV2A 3O64A 3ZUKA 3LE9A 1BUDA 3HBVP 5L79A 1G4KA 1SATA 4IUWA 2OI0A 3F15A 4ON1A 2OW0A 1R1HA 3E8RA 1ND1A 1OMJA 1UMTA 4H2EA 1OM7A 2OZRA 2Y6CA 4GUYA 1EB6A 1KUFA 1SMPA 4H3XA 4GR8A 2OY4A 4L63A 1ATLA 1IADA 2Y6DA 3EDHA 2K9CA 4JA1A 2EROA 2MLSA 3OHLA 1CXVA 2WOAA 3RTSA 5CUHA 1XFVA 1JAPA 1XFZA 1C8TA 4GWMA 1CIZA 5BPAA 5CXAA 1C3IA 2YB9A 4XCTA 3DPFA 2W12A 2K2GA 1RM8A 3O2XA 4FXYP 1JAOA 2DDYA 4JPAA 3CKIA 4DV8A 4HMAA 3VTGA 5D1UA 3DPEA 1JANA 3I7IA 1PWWA 1BZSA 3U1RA 1ASTA 4QKZA 4FVLA 1D5JA 966CA 4PKTA 1GO8P 5I2ZA 1XUDA 3ELMA 3USNA 3LGPA 3DTEA 4AUOA 1ZP5A 2DW0A 4DD8A 1HY7A 1XFWA 1R54A 4PKRA 1GKCA 2E3XA 2MZHA 4R3VA 2W13A 1JKYA 4GWNA 4JP4A 3DSLA 1BQOA 1GE5A 2PJTA 5B5OA 1JJ9A 4GR3A 1I76A 4ZR5A 2AIGP 3AIGA 4HX3A 2ERPA 1SLMA 2YIGA 1GE6A 4XM7A 3ZVSA 1ZVXA 3LUNA 3LIRA 4XBHA 3K7LA 4WKIA 3LMCA 1S4BP 1GXDA 1IACA 3HDBA 1USNA 1PWPA 3LILA 4DPEA 1I73A 1OS9A 1JH1A 2MLRA 1D8FA 3TT4A 2YUFA 5D1SA 4G9LA 4J4MA 3KMEA 3DTKA 1UTZA 1CQRA 1KBCA 4AIGA 1HV5A 1J7NA 2SRTA 4H76A 4PKUA 1MMPA 2USNA 1IABA 2OXUA 4L6TA 3MA2A 1FM1A 1CAQA 4I35A 3WV3A 3DTIA 5D1TA 1MMRA 4L19A 1YQYA 1ZXVA 3KRYA 1FLSA 3EDZA 3KMCA 3BA0A 1KAPP 1QIBA 4WK7A 1G12A 2O36A 2OW2A 1O0QA 4PKVA 4XM8A 2JNPA 2W14A 1D8MA 2JT5A 1B3DA 1GO7P 3HYGA 456CA 1OM8A 1A85A 3N2UA 2ERQA 5BOTA 1BKCI 1UEAA 1AYKA 2OW9A 5I4OA 1EAKA 4Q1LA 4L7AA 1QJIA 3K7NA 4H84A 5I12A 2J83A 3DL1A 2OVZA 3SHIA 3EHYA 1Z3JA 1OM6A 3RTTA 1R55A 3HBUP 5D3CA 1XFYA 2AYKA 3V96B 4EFSA 1ZXCA 5I43A 1PWUA 1DTHA 1IAEA 1YOUA 1SLNA 4XM6A 2QPJA 3DWBA 1KUHA 4A3WA 1SRPA 1R1JA 4IN9A 3EDGA 2N8RA 4PKQA 4DF9A 2RJQA 2XS3A 1MNCA 5D2BA 3EHXA 1D7XA 4WF6A 1QICA 4JQGA 1BIWA 2TCLA 3KEJA 1YCMA 3B8ZA 5BOYA 3ZXHA 5D7WA 1A86A 2JSDA 1DMTA 2OXZA 3LKAA 3LK8A 1OO9A 5I3MA 1PWVA 3P1VA 5JMYA 1QIAA 2MZIA 1BKCA 1MMQA 4I03A 3B92A 1BSWA 3LJTA 2X3BA 1L6JA 3LJGA 1ZTQA 3WV1A 4H30A 4PKSA 5H8XA 5L7FA 1HOVA 3HDAP 1BQQM 1HFSA 2OXWA 4A7BA 2FV9A 1JAQA 1Y8JA 1RMZA 1BKCE 4CTHA 2XS4A 4JIJA 4GF1A 3AYKA 3KHIA 5B5PA 1Y93A 1XFXA 3LUMA 1G05A 3UVCA 4AXQA 1XURA 2CKIA 4GR0A 2CLTA 3G42A 1O0TA 2I47A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AKL A;  1WNI A;  2Z2D A;  4FU4 A;  1R1I A;  2DW2 A;  5I0L A;  3GBO A;  2POJ A;  1CK7 A;  2OW1 A;  4H82 A;  2WO9 A;  3NX7 A;  3EDI A;  4G0D A;  1B8Y A;  3HY7 A;  3HY9 A;  1SU3 A;  1QJJ A;  3F17 A;  1YP1 A;  2DDF A;  5LAB A;  4WKE A;  2WO8 A;  1C7K A;  2X7M A;  3EWJ A;  3LIK A;  2JT6 A;  1H71 P;  3F1A A;  3N2V A;  3LQB A;  1K7G A;  2KRJ A;  1JIW P;  2J0T A;  3L0V A;  1GKD A;  1ROS A;  1G49 A;  4H1Q A;  1Q3A A;  1JIZ A;  3P24 A;  3B2Z A;  2W15 A;  1KUK A;  1GE7 A;  1QUA A;  3TSK A;  3HB2 P;  3Q2H A;  1KUG A;  1UTT A;  3F18 A;  1BUV M;  3KWV C;  2L0R A;  2O3E A;  1HTD A;  2V4B A;  1MMB A;  2D1N A;  1G9K A;  3KEK A;  3Q2G A;  1IAA A;  1EUB A;  4GQL A;  4H49 A;  4ILW D;  3KEC A;  1I1I P;  3VI1 A;  2JIH A;  1JK3 A;  1KUI A;  3L0T A;  1OS2 A;  5CZM A;  3AYU A;  3TVC A;  2HU6 A;  3DNG A;  2DW1 A;  3OHO A;  3F19 A;  1HFC A;  3LQ0 A;  4AYK A;  1IAG A;  1XUC A;  2A8H A;  4WZV A;  1XFU A;  2X3C A;  1K7I A;  1FBL A;  1UMS A;  3F16 A;  1Y0V A;  1BM6 A;  1AF0 A;  4FXQ A;  4IJO A;  2OVX A;  3G5C A;  2FV5 A;  1CGF A;  3LEA A;  2E2D A;  2OY2 A;  4PKW A;  3I7G A;  1ZS0 A;  830C A;  3TS4 A;  1PWQ A;  2D1O A;  1CGE A;  2W0D A;  2X3A A;  2RJP A;  1CGL A;  2MZE A;  1K7Q A;  3LJZ A;  3WV2 A;  3O64 A;  3ZUK A;  3LE9 A;  1BUD A;  3HBV P;  5L79 A;  1G4K A;  1SAT A;  4IUW A;  2OI0 A;  3F15 A;  4ON1 A;  2OW0 A;  1R1H A;  3E8R A;  1ND1 A;  1OMJ A;  1UMT A;  4H2E A;  1OM7 A;  2OZR A;  2Y6C A;  4GUY A;  1EB6 A;  1KUF A;  1SMP A;  4H3X A;  4GR8 A;  2OY4 A;  4L63 A;  1ATL A;  1IAD A;  2Y6D A;  3EDH A;  2K9C A;  4JA1 A;  2ERO A;  2MLS A;  3OHL A;  1CXV A;  2WOA A;  3RTS A;  5CUH A;  1XFV A;  1JAP A;  1XFZ A;  1C8T A;  4GWM A;  1CIZ A;  5BPA A;  5CXA A;  1C3I A;  2YB9 A;  4XCT A;  3DPF A;  2W12 A;  2K2G A;  1RM8 A;  3O2X A;  4FXY P;  1JAO A;  2DDY A;  4JPA A;  3CKI A;  4DV8 A;  4HMA A;  3VTG A;  5D1U A;  3DPE A;  1JAN A;  3I7I A;  1PWW A;  1BZS A;  3U1R A;  1AST A;  4QKZ A;  4FVL A;  1D5J A;  966C A;  4PKT A;  1GO8 P;  5I2Z A;  1XUD A;  3ELM A;  3USN A;  3LGP A;  4AUO A;  1ZP5 A;  2DW0 A;  4DD8 A;  1HY7 A;  1XFW A;  1R54 A;  4PKR A;  1GKC A;  2E3X A;  2MZH A;  4R3V A;  2W13 A;  1JKY A;  4GWN A;  4JP4 A;  3DSL A;  1BQO A;  1GE5 A;  2PJT A;  5B5O A;  1JJ9 A;  4GR3 A;  1I76 A;  4ZR5 A;  2AIG P;  3AIG A;  4HX3 A;  2ERP A;  1SLM A;  2YIG A;  1GE6 A;  4XM7 A;  3ZVS A;  1ZVX A;  3LUN A;  3LIR A;  4XBH A;  3K7L A;  4WKI A;  3LMC A;  1S4B P;  1GXD A;  1IAC A;  3HDB A;  1USN A;  1PWP A;  3LIL A;  4DPE A;  1I73 A;  1OS9 A;  1JH1 A;  2MLR A;  1D8F A;  3TT4 A;  5D1S A;  4G9L A;  4J4M A;  3KME A;  1UTZ A;  1CQR A;  1KBC A;  4AIG A;  1HV5 A;  1J7N A;  2SRT A;  4H76 A;  4PKU A;  1MMP A;  2USN A;  1IAB A;  2OXU A;  4L6T A;  3MA2 A;  1FM1 A;  1CAQ A;  4I35 A;  3WV3 A;  5D1T A;  1MMR A;  4L19 A;  1YQY A;  1ZXV A;  3KRY A;  1FLS A;  3EDZ A;  3KMC A;  3BA0 A;  1KAP P;  1QIB A;  4WK7 A;  1G12 A;  2O36 A;  2OW2 A;  1O0Q A;  4PKV A;  4XM8 A;  2JNP A;  2W14 A;  1D8M A;  2JT5 A;  1B3D A;  1GO7 P;  3HYG A;  456C A;  1OM8 A;  1A85 A;  3N2U A;  2ERQ A;  5BOT A;  1BKC I;  1UEA A;  1AYK A;  2OW9 A;  5I4O A;  1EAK A;  4Q1L A;  1QJI A;  3K7N A;  4H84 A;  5I12 A;  2J83 A;  3DL1 A;  2OVZ A;  3SHI A;  3EHY A;  1Z3J A;  1OM6 A;  3RTT A;  1R55 A;  3HBU P;  5D3C A;  1XFY A;  2AYK A;  3V96 B;  4EFS A;  1ZXC A;  5I43 A;  1PWU A;  1DTH A;  1IAE A;  1YOU A;  1SLN A;  4XM6 A;  2QPJ A;  3DWB A;  1KUH A;  4A3W A;  1SRP A;  1R1J A;  4IN9 A;  3EDG A;  2N8R A;  4PKQ A;  4DF9 A;  2RJQ A;  2XS3 A;  1MNC A;  5D2B A;  3EHX A;  1D7X A;  4WF6 A;  1QIC A;  4JQG A;  1BIW A;  2TCL A;  3KEJ A;  1YCM A;  3B8Z A;  5BOY A;  3ZXH A;  5D7W A;  1A86 A;  2JSD A;  1DMT A;  2OXZ A;  3LKA A;  3LK8 A;  1OO9 A;  5I3M A;  1PWV A;  3P1V A;  5JMY A;  1QIA A;  2MZI A;  1BKC A;  1MMQ A;  4I03 A;  3B92 A;  1BSW A;  3LJT A;  2X3B A;  1L6J A;  3LJG A;  1ZTQ A;  3WV1 A;  4H30 A;  4PKS A;  5H8X A;  5L7F A;  1HOV A;  3HDA P;  1BQQ M;  1HFS A;  2OXW A;  4A7B A;  2FV9 A;  1JAQ A;  1Y8J A;  1RMZ A;  1BKC E;  4CTH A;  2XS4 A;  4JIJ A;  4GF1 A;  3AYK A;  3KHI A;  5B5P A;  1Y93 A;  1XFX A;  3LUM A;  1G05 A;  3UVC A;  4AXQ A;  1XUR A;  2CKI A;  4GR0 A;  2CLT A;  3G42 A;  1O0T A;  2I47 A; 
#chains in the Genus database with same CATH topology
 1AKL A;  1WNI A;  2Z2D A;  4FU4 A;  1R1I A;  2DW2 A;  5I0L A;  3GBO A;  2POJ A;  1CK7 A;  2OW1 A;  4H82 A;  2WO9 A;  3NX7 A;  3EDI A;  4G0D A;  1B8Y A;  3HY7 A;  3HY9 A;  1SU3 A;  1QJJ A;  3F17 A;  1YP1 A;  2DDF A;  5LAB A;  4WKE A;  2WO8 A;  1C7K A;  2X7M A;  3EWJ A;  3LIK A;  2JT6 A;  1H71 P;  3F1A A;  3N2V A;  3LQB A;  1K7G A;  2KRJ A;  1JIW P;  2J0T A;  3L0V A;  1GKD A;  1ROS A;  1G49 A;  4H1Q A;  1Q3A A;  1JIZ A;  3P24 A;  3B2Z A;  2W15 A;  1KUK A;  1GE7 A;  1QUA A;  3TSK A;  3HB2 P;  3Q2H A;  1KUG A;  1UTT A;  3F18 A;  1BUV M;  3KWV C;  2L0R A;  2O3E A;  1HTD A;  2V4B A;  1MMB A;  2D1N A;  1G9K A;  3KEK A;  3Q2G A;  1IAA A;  1EUB A;  4GQL A;  4H49 A;  4ILW D;  3KEC A;  1I1I P;  3VI1 A;  2JIH A;  1JK3 A;  1KUI A;  3L0T A;  1OS2 A;  5CZM A;  3AYU A;  3TVC A;  2HU6 A;  3DNG A;  2DW1 A;  3OHO A;  3F19 A;  1HFC A;  3LQ0 A;  4AYK A;  1IAG A;  1XUC A;  2A8H A;  4WZV A;  1XFU A;  2X3C A;  1K7I A;  1FBL A;  1UMS A;  3F16 A;  1Y0V A;  1BM6 A;  1AF0 A;  4FXQ A;  4IJO A;  2OVX A;  3G5C A;  2FV5 A;  1CGF A;  3LEA A;  2E2D A;  2OY2 A;  4PKW A;  3I7G A;  1ZS0 A;  830C A;  3TS4 A;  1PWQ A;  2D1O A;  1CGE A;  2W0D A;  2X3A A;  2RJP A;  1CGL A;  2MZE A;  1K7Q A;  3LJZ A;  3WV2 A;  3O64 A;  3ZUK A;  1XM5 A;  3LE9 A;  1BUD A;  3HBV P;  5L79 A;  1G4K A;  1SAT A;  4IUW A;  2OI0 A;  3F15 A;  4ON1 A;  2OW0 A;  1R1H A;  3E8R A;  1ND1 A;  1OMJ A;  1UMT A;  4H2E A;  1OM7 A;  2OZR A;  2Y6C A;  4GUY A;  1EB6 A;  1KUF A;  1SMP A;  4H3X A;  4GR8 A;  2OY4 A;  4L63 A;  1ATL A;  1IAD A;  2Y6D A;  3EDH A;  2K9C A;  4JA1 A;  2ERO A;  2MLS A;  1OZ9 A;  3OHL A;  1CXV A;  2WOA A;  3RTS A;  5CUH A;  1XFV A;  1JAP A;  1XFZ A;  1C8T A;  4GWM A;  1CIZ A;  5BPA A;  5CXA A;  1C3I A;  2YB9 A;  4XCT A;  3DPF A;  2W12 A;  2K2G A;  1RM8 A;  3O2X A;  4FXY P;  1JAO A;  2DDY A;  4JPA A;  3CKI A;  4DV8 A;  4HMA A;  3VTG A;  5D1U A;  3DPE A;  1JAN A;  3I7I A;  1PWW A;  1BZS A;  3U1R A;  1AST A;  4QKZ A;  4FVL A;  1D5J A;  966C A;  4PKT A;  1GO8 P;  5I2Z A;  1XUD A;  3ELM A;  3USN A;  3LGP A;  3DTE A;  4AUO A;  1ZP5 A;  2DW0 A;  4DD8 A;  1HY7 A;  1XFW A;  1R54 A;  4PKR A;  1GKC A;  2E3X A;  2MZH A;  4R3V A;  2W13 A;  1JKY A;  4GWN A;  4JP4 A;  3DSL A;  1BQO A;  1GE5 A;  2PJT A;  5B5O A;  1JJ9 A;  4GR3 A;  1I76 A;  4ZR5 A;  2AIG P;  3AIG A;  4HX3 A;  2ERP A;  1SLM A;  2YIG A;  1GE6 A;  4XM7 A;  3ZVS A;  1ZVX A;  3LUN A;  3LIR A;  4XBH A;  3K7L A;  4WKI A;  3LMC A;  1S4B P;  1GXD A;  1IAC A;  3HDB A;  1USN A;  1PWP A;  3LIL A;  4DPE A;  1I73 A;  1OS9 A;  1JH1 A;  2MLR A;  1D8F A;  3TT4 A;  2YUF A;  5D1S A;  4G9L A;  4J4M A;  3KME A;  1XAX A;  3DTK A;  1UTZ A;  1CQR A;  1KBC A;  4AIG A;  1HV5 A;  1J7N A;  2SRT A;  4H76 A;  4PKU A;  1MMP A;  2USN A;  1IAB A;  2OXU A;  4L6T A;  3MA2 A;  1FM1 A;  1CAQ A;  4I35 A;  3WV3 A;  3DTI A;  5D1T A;  1MMR A;  4L19 A;  1YQY A;  1ZXV A;  3KRY A;  1FLS A;  3EDZ A;  3KMC A;  3BA0 A;  1KAP P;  1QIB A;  4WK7 A;  1G12 A;  2O36 A;  2OW2 A;  1O0Q A;  4PKV A;  4XM8 A;  2JNP A;  2W14 A;  1D8M A;  2JT5 A;  1B3D A;  1GO7 P;  3HYG A;  456C A;  1OM8 A;  1A85 A;  3N2U A;  2ERQ A;  5BOT A;  1BKC I;  1UEA A;  1AYK A;  2OW9 A;  5I4O A;  1EAK A;  4Q1L A;  4L7A A;  1QJI A;  3K7N A;  4H84 A;  5I12 A;  2J83 A;  3DL1 A;  2OVZ A;  3SHI A;  3EHY A;  1Z3J A;  1OM6 A;  3RTT A;  1R55 A;  3HBU P;  5D3C A;  1XFY A;  2AYK A;  3V96 B;  4EFS A;  1ZXC A;  5I43 A;  1PWU A;  1DTH A;  1IAE A;  1YOU A;  1SLN A;  4XM6 A;  2QPJ A;  3DWB A;  1KUH A;  4A3W A;  1SRP A;  1R1J A;  4IN9 A;  3EDG A;  2N8R A;  4PKQ A;  4DF9 A;  2RJQ A;  2XS3 A;  1MNC A;  5D2B A;  3EHX A;  1D7X A;  4WF6 A;  1QIC A;  4JQG A;  1BIW A;  2TCL A;  3KEJ A;  1YCM A;  3B8Z A;  5BOY A;  3ZXH A;  5D7W A;  1A86 A;  2JSD A;  1DMT A;  2OXZ A;  3LKA A;  3LK8 A;  1OO9 A;  5I3M A;  1PWV A;  3P1V A;  5JMY A;  1QIA A;  2MZI A;  1BKC A;  1MMQ A;  4I03 A;  3B92 A;  1BSW A;  3LJT A;  2X3B A;  1L6J A;  3LJG A;  1ZTQ A;  3WV1 A;  4H30 A;  4PKS A;  5H8X A;  5L7F A;  1HOV A;  1TVI A;  3HDA P;  1BQQ M;  1HFS A;  2OXW A;  4A7B A;  2FV9 A;  1JAQ A;  1Y8J A;  1RMZ A;  1BKC E;  4CTH A;  2XS4 A;  4JIJ A;  4GF1 A;  3AYK A;  3KHI A;  5B5P A;  1Y93 A;  1XFX A;  3LUM A;  1G05 A;  3UVC A;  4AXQ A;  1XUR A;  2CKI A;  4GR0 A;  2CLT A;  3G42 A;  1O0T A;  2I47 A; 
#chains in the Genus database with same CATH homology
 1AKL A;  1WNI A;  2Z2D A;  4FU4 A;  1R1I A;  2DW2 A;  5I0L A;  3GBO A;  2POJ A;  1CK7 A;  2OW1 A;  4H82 A;  2WO9 A;  3NX7 A;  3EDI A;  4G0D A;  1B8Y A;  3HY7 A;  3HY9 A;  1SU3 A;  1QJJ A;  3F17 A;  1YP1 A;  2DDF A;  5LAB A;  4WKE A;  2WO8 A;  1C7K A;  2X7M A;  3EWJ A;  3LIK A;  2JT6 A;  1H71 P;  3F1A A;  3N2V A;  3LQB A;  1K7G A;  2KRJ A;  1JIW P;  2J0T A;  3L0V A;  1GKD A;  1ROS A;  1G49 A;  4H1Q A;  1Q3A A;  1JIZ A;  3P24 A;  3B2Z A;  2W15 A;  1KUK A;  1GE7 A;  1QUA A;  3TSK A;  3HB2 P;  3Q2H A;  1KUG A;  1UTT A;  3F18 A;  1BUV M;  3KWV C;  2L0R A;  2O3E A;  1HTD A;  2V4B A;  1MMB A;  2D1N A;  1G9K A;  3KEK A;  3Q2G A;  1IAA A;  1EUB A;  4GQL A;  4H49 A;  4ILW D;  3KEC A;  1I1I P;  3VI1 A;  2JIH A;  1JK3 A;  1KUI A;  3L0T A;  1OS2 A;  5CZM A;  3AYU A;  3TVC A;  2HU6 A;  3DNG A;  2DW1 A;  3OHO A;  3F19 A;  1HFC A;  3LQ0 A;  4AYK A;  1IAG A;  1XUC A;  2A8H A;  4WZV A;  1XFU A;  2X3C A;  1K7I A;  1FBL A;  1UMS A;  3F16 A;  1Y0V A;  1BM6 A;  1AF0 A;  4FXQ A;  4IJO A;  2OVX A;  3G5C A;  2FV5 A;  1CGF A;  3LEA A;  2E2D A;  2OY2 A;  4PKW A;  3I7G A;  1ZS0 A;  830C A;  3TS4 A;  1PWQ A;  2D1O A;  1CGE A;  2W0D A;  2X3A A;  2RJP A;  1CGL A;  2MZE A;  1K7Q A;  3LJZ A;  3WV2 A;  3O64 A;  3ZUK A;  3LE9 A;  1BUD A;  3HBV P;  5L79 A;  1G4K A;  1SAT A;  4IUW A;  2OI0 A;  3F15 A;  4ON1 A;  2OW0 A;  1R1H A;  3E8R A;  1ND1 A;  1OMJ A;  1UMT A;  4H2E A;  1OM7 A;  2OZR A;  2Y6C A;  4GUY A;  1EB6 A;  1KUF A;  1SMP A;  4H3X A;  4GR8 A;  2OY4 A;  4L63 A;  1ATL A;  1IAD A;  2Y6D A;  3EDH A;  2K9C A;  4JA1 A;  2ERO A;  2MLS A;  3OHL A;  1CXV A;  2WOA A;  3RTS A;  5CUH A;  1XFV A;  1JAP A;  1XFZ A;  1C8T A;  4GWM A;  1CIZ A;  5BPA A;  5CXA A;  1C3I A;  2YB9 A;  4XCT A;  3DPF A;  2W12 A;  2K2G A;  1RM8 A;  3O2X A;  4FXY P;  1JAO A;  2DDY A;  4JPA A;  3CKI A;  4DV8 A;  4HMA A;  3VTG A;  5D1U A;  3DPE A;  1JAN A;  3I7I A;  1PWW A;  1BZS A;  3U1R A;  1AST A;  4QKZ A;  4FVL A;  1D5J A;  966C A;  4PKT A;  1GO8 P;  5I2Z A;  1XUD A;  3ELM A;  3USN A;  3LGP A;  3DTE A;  4AUO A;  1ZP5 A;  2DW0 A;  4DD8 A;  1HY7 A;  1XFW A;  1R54 A;  4PKR A;  1GKC A;  2E3X A;  2MZH A;  4R3V A;  2W13 A;  1JKY A;  4GWN A;  4JP4 A;  3DSL A;  1BQO A;  1GE5 A;  2PJT A;  5B5O A;  1JJ9 A;  4GR3 A;  1I76 A;  4ZR5 A;  2AIG P;  3AIG A;  4HX3 A;  2ERP A;  1SLM A;  2YIG A;  1GE6 A;  4XM7 A;  3ZVS A;  1ZVX A;  3LUN A;  3LIR A;  4XBH A;  3K7L A;  4WKI A;  3LMC A;  1S4B P;  1GXD A;  1IAC A;  3HDB A;  1USN A;  1PWP A;  3LIL A;  4DPE A;  1I73 A;  1OS9 A;  1JH1 A;  2MLR A;  1D8F A;  3TT4 A;  2YUF A;  5D1S A;  4G9L A;  4J4M A;  3KME A;  3DTK A;  1UTZ A;  1CQR A;  1KBC A;  4AIG A;  1HV5 A;  1J7N A;  2SRT A;  4H76 A;  4PKU A;  1MMP A;  2USN A;  1IAB A;  2OXU A;  4L6T A;  3MA2 A;  1FM1 A;  1CAQ A;  4I35 A;  3WV3 A;  3DTI A;  5D1T A;  1MMR A;  4L19 A;  1YQY A;  1ZXV A;  3KRY A;  1FLS A;  3EDZ A;  3KMC A;  3BA0 A;  1KAP P;  1QIB A;  4WK7 A;  1G12 A;  2O36 A;  2OW2 A;  1O0Q A;  4PKV A;  4XM8 A;  2JNP A;  2W14 A;  1D8M A;  2JT5 A;  1B3D A;  1GO7 P;  3HYG A;  456C A;  1OM8 A;  1A85 A;  3N2U A;  2ERQ A;  5BOT A;  1BKC I;  1UEA A;  1AYK A;  2OW9 A;  5I4O A;  1EAK A;  4Q1L A;  4L7A A;  1QJI A;  3K7N A;  4H84 A;  5I12 A;  2J83 A;  3DL1 A;  2OVZ A;  3SHI A;  3EHY A;  1Z3J A;  1OM6 A;  3RTT A;  1R55 A;  3HBU P;  5D3C A;  1XFY A;  2AYK A;  3V96 B;  4EFS A;  1ZXC A;  5I43 A;  1PWU A;  1DTH A;  1IAE A;  1YOU A;  1SLN A;  4XM6 A;  2QPJ A;  3DWB A;  1KUH A;  4A3W A;  1SRP A;  1R1J A;  4IN9 A;  3EDG A;  2N8R A;  4PKQ A;  4DF9 A;  2RJQ A;  2XS3 A;  1MNC A;  5D2B A;  3EHX A;  1D7X A;  4WF6 A;  1QIC A;  4JQG A;  1BIW A;  2TCL A;  3KEJ A;  1YCM A;  3B8Z A;  5BOY A;  3ZXH A;  5D7W A;  1A86 A;  2JSD A;  1DMT A;  2OXZ A;  3LKA A;  3LK8 A;  1OO9 A;  5I3M A;  1PWV A;  3P1V A;  5JMY A;  1QIA A;  2MZI A;  1BKC A;  1MMQ A;  4I03 A;  3B92 A;  1BSW A;  3LJT A;  2X3B A;  1L6J A;  3LJG A;  1ZTQ A;  3WV1 A;  4H30 A;  4PKS A;  5H8X A;  5L7F A;  1HOV A;  3HDA P;  1BQQ M;  1HFS A;  2OXW A;  4A7B A;  2FV9 A;  1JAQ A;  1Y8J A;  1RMZ A;  1BKC E;  4CTH A;  2XS4 A;  4JIJ A;  4GF1 A;  3AYK A;  3KHI A;  5B5P A;  1Y93 A;  1XFX A;  3LUM A;  1G05 A;  3UVC A;  4AXQ A;  1XUR A;  2CKI A;  4GR0 A;  2CLT A;  3G42 A;  1O0T A;  2I47 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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