3LKAA

Catalytic domain of human mmp-12 complexed with hydroxamic acid and paramethoxy-sulfonyl amide
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
158
structure length
158
Chain Sequence
GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Entropic contribution to the linking coefficient in fragment based drug design: a case study.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Macrophage metalloelastase
total genus 45
structure length 158
sequence length 158
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2010-01-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3lkaA00
2O36A 2X3BA 3ZVSA 3K7NA 4WZVA 5I43A 1YOUA 2OY2A 1XUDA 3F17A 4GWNA 1ZXCA 1QIBA 4AUOA 1I1IP 4WF6A 4HMAA 1G05A 4FU4A 3O2XA 1JAPA 4ZR5A 4DD8A 3AYKA 5BOYA 3F15A 1JAOA 3LJGA 2Y6CA 1GE5A 4DF9A 3HDBA 3OHOA 3B2ZA 1D8FA 4JPAA 2AIGP 1IABA 1H71P 3HY9A 1QUAA 2W15A 1PWPA 1GKDA 3F18A 5L7FA 5I2ZA 3EWJA 1K7GA 4H2EA 2X3CA 3UVCA 3ZXHA 1EUBA 4AXQA 1R54A 3LKAA 2MZEA 3P1VA 3KRYA 1KUHA 2USNA 1R1IA 3EDZA 1IAEA 3EDIA 2W12A 1C3IA 2J0TA 1YQYA 4GUYA 5CXAA 1CAQA 1QJIA 1UMSA 1HTDA 1I76A 1XUCA 2O3EA 1RM8A 1B8YA 4GR0A 1G12A 2OW0A 2RJPA 1JK3A 5JMYA 1JJ9A 1JKYA 2OI0A 2WOAA 1Y0VA 2QPJA 3EHYA 4GF1A 2K9CA 4XCTA 3I7GA 1D5JA 2V4BA 2JT5A 1S4BP 1OS9A 1K7QA 3U1RA 3LMCA 1C7KA 3LJTA 5CUHA 3KEJA 4I03A 4EFSA 2OVXA 1PWQA 3LEAA 1OM6A 2K2GA 2OZRA 2JNPA 3N2VA 2OW1A 4FVLA 1DMTA 2MZIA 1G49A 2D1NA 2YIGA 1A85A 4GWMA 5B5PA 2OVZA 2X7MA 1EB6A 1L6JA 5D7WA 1KUKA 3ELMA 1USNA 2OXZA 4IN9A 2FV9A 1XFXA 3NX7A 1O0QA 1QJJA 3CKIA 1FM1A 3LIRA 2AYKA 4FXQA 1J7NA 2KRJA 4GQLA 4FXYP 1G9KA 4G0DA 4H3XA 4PKRA 1DTHA 1CGEA 1MMRA 1BQQM 4Q1LA 5H8XA 1KUGA 4GR8A 4XBHA 1YCMA 1BZSA 1HFSA 2EROA 2FV5A 2RJQA 4WKEA 3VI1A 3O64A 2CKIA 3LQBA 1MMBA 4IJOA 5D1UA 2E3XA 3OHLA 1IADA 4GR3A 1CGFA 4HX3A 3KWVC 4DV8A 3KECA 2I47A 3K7LA 1BQOA 3AYUA 4L63A 1JIZA 1FLSA 1ZS0A 1SLMA 1IAAA 3F1AA 2MLSA 1GO8P 3TT4A 2JSDA 1D8MA 1ZXVA 2PJTA 1UEAA 3SHIA 3B92A 1ZTQA 2MZHA 4I35A 3WV3A 1MMPA 3DSLA 5D1TA 4H76A 2DDFA 1OS2A 3I7IA 4L19A 1AF0A 1JAQA 3LILA 5D2BA 1A86A 1BKCE 5D3CA 4L6TA 3LUMA 4H84A 3V96B 1BIWA 3TVCA 4PKTA 2W13A 1SU3A 1R1JA 4JA1A 1SRPA 5D1SA 1OMJA 2SRTA 1XFZA 2OW9A 1HY7A 1HOVA 1C8TA 1BUDA 1SMPA 1UTZA 2Z2DA 3L0TA 3LJZA 1MMQA 1WNIA 1MNCA 1GE6A 1R1HA 1UTTA 3RTSA 3USNA 2CLTA 3DNGA 1G4KA 3G5CA 4PKSA 3GBOA 2W0DA 4A3WA 1B3DA 5I4OA 3TSKA 2ERQA 1KBCA 1ATLA 1AYKA 1QICA 1GE7A 4A7BA 1PWUA 1Z3JA 1BM6A 3LUNA 3BA0A 2WO9A 1JH1A 1CIZA 2MLRA 3Q2HA 3HB2P 1XFUA 1HV5A 1ROSA 3HDAP 2E2DA 2W14A 3EDHA 1PWVA 2OW2A 1Y8JA 2XS4A 1BSWA 1R55A 830CA 4WK7A 3TS4A 1GO7P 1XFYA 2ERPA 1XFWA 3HBUP 2J83A 3ZUKA 2JIHA 4JQGA 3LGPA 4IUWA 1XURA 4XM7A 4H1QA 2POJA 4H49A 1CK7A 3EDGA 2Y6DA 4WKIA 1KAPP 1BKCA 3DWBA 2YB9A 2DW2A 4R3VA 2XS3A 3WV2A 3F16A 3L0VA 1CGLA 4AIGA 4H30A 5L79A 3LK8A 4XM6A 2A8HA 5CZMA 1FBLA 4PKQA 1OM8A 3HYGA 3WV1A 3DL1A 1ND1A 1Q3AA 2X3AA 3DPFA 4ON1A 3KEKA 1RMZA 2JT6A 3HY7A 1EAKA 1XFVA 1CXVA 3DPEA 1IAGA 5BPAA 3E8RA 3P24A 456CA 3Q2GA 4PKVA 4H82A 3KMCA 1I73A 1D7XA 1IACA 3LIKA 1Y93A 1JIWP 4XM8A 4DPEA 2DDYA 2OXUA 4JP4A 1PWWA 4ILWD 1BUVM 1SATA 1ZVXA 1K7IA 3B8ZA 1ZP5A 2WO8A 1HFCA 4JIJA 5BOTA 3EHXA 3HBVP 1YP1A 3KHIA 1KUIA 1UMTA 2DW1A 4PKUA 4CTHA 3LE9A 5I3MA 2HU6A 5B5OA 3MA2A 1JANA 3KMEA 3F19A 2OXWA 1CQRA 1OM7A 1BKCI 1GXDA 1O0TA 2N8RA 1KUFA 1OO9A 4J4MA 5LABA 4PKWA 1GKCA 3AIGA 4G9LA 4QKZA 3N2UA 5I0LA 3G42A 1SLNA 4AYKA 1ASTA 966CA 1AKLA 2D1OA 1QIAA 2DW0A 3LQ0A 2L0RA 5I12A 2TCLA 3VTGA 2OY4A 3RTTA
chains in the Genus database with same CATH superfamily
2O36A 2X3BA 3ZVSA 3K7NA 4WZVA 5I43A 1YOUA 2OY2A 1XUDA 3F17A 4GWNA 1ZXCA 1QIBA 4AUOA 1I1IP 4WF6A 4HMAA 1G05A 4FU4A 3O2XA 1JAPA 4ZR5A 4DD8A 3AYKA 5BOYA 3F15A 1JAOA 3LJGA 2Y6CA 1GE5A 4DF9A 3HDBA 3OHOA 3B2ZA 1D8FA 4JPAA 2AIGP 1IABA 1H71P 3HY9A 1QUAA 2W15A 1PWPA 1GKDA 3F18A 5L7FA 5I2ZA 3EWJA 1K7GA 4H2EA 2X3CA 3UVCA 3ZXHA 1EUBA 4AXQA 1R54A 3LKAA 2MZEA 3P1VA 3KRYA 1KUHA 2USNA 1R1IA 3EDZA 1IAEA 3EDIA 2W12A 1C3IA 2J0TA 1YQYA 4GUYA 5CXAA 1CAQA 1QJIA 1UMSA 1HTDA 1I76A 1XUCA 2O3EA 1RM8A 1B8YA 4GR0A 1G12A 2OW0A 2RJPA 1JK3A 5JMYA 1JJ9A 1JKYA 2OI0A 2WOAA 1Y0VA 2QPJA 3EHYA 4GF1A 2K9CA 4XCTA 3I7GA 1D5JA 3DTEA 2V4BA 2JT5A 1S4BP 1OS9A 1K7QA 3U1RA 3LMCA 1C7KA 3LJTA 5CUHA 3KEJA 4I03A 4EFSA 2OVXA 1PWQA 3LEAA 1OM6A 2K2GA 2OZRA 2JNPA 3N2VA 2OW1A 4FVLA 1DMTA 2MZIA 1G49A 2D1NA 2YIGA 1A85A 4GWMA 5B5PA 2OVZA 2X7MA 1EB6A 1L6JA 5D7WA 1KUKA 3ELMA 1USNA 2OXZA 1XAXA 4IN9A 2FV9A 1XFXA 3NX7A 1O0QA 1QJJA 3CKIA 1FM1A 3LIRA 2AYKA 4FXQA 1J7NA 2KRJA 4GQLA 4FXYP 3DTKA 1G9KA 4G0DA 4H3XA 2YUFA 4PKRA 1DTHA 1CGEA 1MMRA 1BQQM 4Q1LA 5H8XA 1KUGA 4GR8A 4XBHA 1YCMA 3DTIA 1BZSA 1HFSA 2EROA 2FV5A 2RJQA 4WKEA 3VI1A 3O64A 2CKIA 3LQBA 1MMBA 4IJOA 5D1UA 2E3XA 3OHLA 1IADA 4GR3A 1CGFA 4HX3A 3KWVC 4DV8A 3KECA 2I47A 3K7LA 1BQOA 3AYUA 4L63A 1JIZA 1FLSA 1ZS0A 1SLMA 1IAAA 3F1AA 2MLSA 1GO8P 3TT4A 2JSDA 1D8MA 1ZXVA 2PJTA 1UEAA 3SHIA 3B92A 1ZTQA 2MZHA 1TVIA 4I35A 3WV3A 1MMPA 3DSLA 5D1TA 4H76A 2DDFA 1OS2A 3I7IA 4L19A 1AF0A 1JAQA 3LILA 5D2BA 1A86A 1BKCE 5D3CA 4L6TA 3LUMA 4H84A 3V96B 1BIWA 3TVCA 4PKTA 2W13A 1SU3A 1R1JA 4JA1A 1SRPA 5D1SA 1OMJA 2SRTA 1XFZA 2OW9A 1HY7A 1HOVA 1C8TA 1BUDA 1SMPA 1UTZA 2Z2DA 3L0TA 3LJZA 1MMQA 1WNIA 1MNCA 1GE6A 1R1HA 1UTTA 3RTSA 3USNA 2CLTA 3DNGA 1G4KA 3G5CA 4PKSA 3GBOA 2W0DA 4A3WA 1B3DA 5I4OA 3TSKA 2ERQA 1KBCA 1ATLA 1AYKA 1QICA 1GE7A 4A7BA 1PWUA 1Z3JA 1BM6A 3LUNA 3BA0A 2WO9A 1JH1A 1CIZA 2MLRA 3Q2HA 3HB2P 1XFUA 1HV5A 1ROSA 3HDAP 2E2DA 2W14A 3EDHA 1PWVA 2OW2A 1Y8JA 2XS4A 1BSWA 1R55A 830CA 4WK7A 3TS4A 1GO7P 1XFYA 2ERPA 1XFWA 3HBUP 2J83A 3ZUKA 2JIHA 4JQGA 3LGPA 4IUWA 1XURA 4XM7A 4H1QA 2POJA 4H49A 1CK7A 3EDGA 2Y6DA 4WKIA 1KAPP 1BKCA 3DWBA 2YB9A 2DW2A 4R3VA 2XS3A 3WV2A 3F16A 3L0VA 1CGLA 4AIGA 4H30A 5L79A 3LK8A 4XM6A 2A8HA 5CZMA 1FBLA 4PKQA 1OM8A 3HYGA 3WV1A 3DL1A 1ND1A 1Q3AA 2X3AA 3DPFA 4ON1A 3KEKA 1RMZA 2JT6A 3HY7A 1EAKA 1XFVA 1CXVA 3DPEA 1IAGA 5BPAA 3E8RA 3P24A 456CA 3Q2GA 4PKVA 4H82A 3KMCA 1I73A 1D7XA 1IACA 3LIKA 1Y93A 1JIWP 4XM8A 4DPEA 2DDYA 4L7AA 2OXUA 4JP4A 1PWWA 4ILWD 1BUVM 1SATA 1ZVXA 1K7IA 3B8ZA 1ZP5A 2WO8A 1HFCA 4JIJA 5BOTA 3EHXA 3HBVP 1YP1A 3KHIA 1KUIA 1UMTA 2DW1A 4PKUA 4CTHA 3LE9A 5I3MA 2HU6A 5B5OA 3MA2A 1JANA 3KMEA 3F19A 2OXWA 1CQRA 1OM7A 1BKCI 1GXDA 1O0TA 2N8RA 1KUFA 1OO9A 4J4MA 5LABA 4PKWA 1GKCA 3AIGA 4G9LA 4QKZA 3N2UA 5I0LA 3G42A 1XM5A 1SLNA 1OZ9A 4AYKA 1ASTA 966CA 1AKLA 2D1OA 1QIAA 2DW0A 3LQ0A 2L0RA 5I12A 2TCLA 3VTGA 2OY4A 3RTTA
chains in the Genus database with same CATH topology
2O36A 2X3BA 3ZVSA 3K7NA 4WZVA 5I43A 1YOUA 2OY2A 1XUDA 3F17A 4GWNA 1ZXCA 1QIBA 4AUOA 1I1IP 4WF6A 4HMAA 1G05A 4FU4A 3O2XA 1JAPA 4ZR5A 4DD8A 3AYKA 5BOYA 3F15A 1JAOA 3LJGA 2Y6CA 1GE5A 4DF9A 3HDBA 3OHOA 3B2ZA 1D8FA 4JPAA 2AIGP 1IABA 1H71P 3HY9A 1QUAA 2W15A 1PWPA 1GKDA 3F18A 5L7FA 5I2ZA 3EWJA 1K7GA 4H2EA 2X3CA 3UVCA 3ZXHA 1EUBA 4AXQA 1R54A 3LKAA 2MZEA 3P1VA 3KRYA 1KUHA 2USNA 1R1IA 3EDZA 1IAEA 3EDIA 2W12A 1C3IA 2J0TA 1YQYA 4GUYA 5CXAA 1CAQA 1QJIA 1UMSA 1HTDA 1I76A 1XUCA 2O3EA 1RM8A 1B8YA 4GR0A 1G12A 2OW0A 2RJPA 1JK3A 5JMYA 1JJ9A 1JKYA 2OI0A 2WOAA 1Y0VA 2QPJA 3EHYA 4GF1A 2K9CA 4XCTA 3I7GA 1D5JA 3DTEA 2V4BA 2JT5A 1S4BP 1OS9A 1K7QA 3U1RA 3LMCA 1C7KA 3LJTA 5CUHA 3KEJA 4I03A 4EFSA 2OVXA 1PWQA 3LEAA 1OM6A 2K2GA 2OZRA 2JNPA 3N2VA 2OW1A 4FVLA 1DMTA 2MZIA 1G49A 2D1NA 2YIGA 1A85A 4GWMA 5B5PA 2OVZA 2X7MA 1EB6A 1L6JA 5D7WA 1KUKA 3ELMA 1USNA 2OXZA 4IN9A 2FV9A 1XFXA 3NX7A 1O0QA 1QJJA 3CKIA 1FM1A 3LIRA 2AYKA 4FXQA 1J7NA 2KRJA 4GQLA 4FXYP 3DTKA 1G9KA 4G0DA 4H3XA 2YUFA 4PKRA 1DTHA 1CGEA 1MMRA 1BQQM 4Q1LA 5H8XA 1KUGA 4GR8A 4XBHA 1YCMA 3DTIA 1BZSA 1HFSA 2EROA 2FV5A 2RJQA 4WKEA 3VI1A 3O64A 2CKIA 3LQBA 1MMBA 4IJOA 5D1UA 2E3XA 3OHLA 1IADA 4GR3A 1CGFA 4HX3A 3KWVC 4DV8A 3KECA 2I47A 3K7LA 1BQOA 3AYUA 4L63A 1JIZA 1FLSA 1ZS0A 1SLMA 1IAAA 3F1AA 2MLSA 1GO8P 3TT4A 2JSDA 1D8MA 1ZXVA 2PJTA 1UEAA 3SHIA 3B92A 1ZTQA 2MZHA 4I35A 3WV3A 1MMPA 3DSLA 5D1TA 4H76A 2DDFA 1OS2A 3I7IA 4L19A 1AF0A 1JAQA 3LILA 5D2BA 1A86A 1BKCE 5D3CA 4L6TA 3LUMA 4H84A 3V96B 1BIWA 3TVCA 4PKTA 2W13A 1SU3A 1R1JA 4JA1A 1SRPA 5D1SA 1OMJA 2SRTA 1XFZA 2OW9A 1HY7A 1HOVA 1C8TA 1BUDA 1SMPA 1UTZA 2Z2DA 3L0TA 3LJZA 1MMQA 1WNIA 1MNCA 1GE6A 1R1HA 1UTTA 3RTSA 3USNA 2CLTA 3DNGA 1G4KA 3G5CA 4PKSA 3GBOA 2W0DA 4A3WA 1B3DA 5I4OA 3TSKA 2ERQA 1KBCA 1ATLA 1AYKA 1QICA 1GE7A 4A7BA 1PWUA 1Z3JA 1BM6A 3LUNA 3BA0A 2WO9A 1JH1A 1CIZA 2MLRA 3Q2HA 3HB2P 1XFUA 1HV5A 1ROSA 3HDAP 2E2DA 2W14A 3EDHA 1PWVA 2OW2A 1Y8JA 2XS4A 1BSWA 1R55A 830CA 4WK7A 3TS4A 1GO7P 1XFYA 2ERPA 1XFWA 3HBUP 2J83A 3ZUKA 2JIHA 4JQGA 3LGPA 4IUWA 1XURA 4XM7A 4H1QA 2POJA 4H49A 1CK7A 3EDGA 2Y6DA 4WKIA 1KAPP 1BKCA 3DWBA 2YB9A 2DW2A 4R3VA 2XS3A 3WV2A 3F16A 3L0VA 1CGLA 4AIGA 4H30A 5L79A 3LK8A 4XM6A 2A8HA 5CZMA 1FBLA 4PKQA 1OM8A 3HYGA 3WV1A 3DL1A 1ND1A 1Q3AA 2X3AA 3DPFA 4ON1A 3KEKA 1RMZA 2JT6A 3HY7A 1EAKA 1XFVA 1CXVA 3DPEA 1IAGA 5BPAA 3E8RA 3P24A 456CA 3Q2GA 4PKVA 4H82A 3KMCA 1I73A 1D7XA 1IACA 3LIKA 1Y93A 1JIWP 4XM8A 4DPEA 2DDYA 4L7AA 2OXUA 4JP4A 1PWWA 4ILWD 1BUVM 1SATA 1ZVXA 1K7IA 3B8ZA 1ZP5A 2WO8A 1HFCA 4JIJA 5BOTA 3EHXA 3HBVP 1YP1A 3KHIA 1KUIA 1UMTA 2DW1A 4PKUA 4CTHA 3LE9A 5I3MA 2HU6A 5B5OA 3MA2A 1JANA 3KMEA 3F19A 2OXWA 1CQRA 1OM7A 1BKCI 1GXDA 1O0TA 2N8RA 1KUFA 1OO9A 4J4MA 5LABA 4PKWA 1GKCA 3AIGA 4G9LA 4QKZA 3N2UA 5I0LA 3G42A 1SLNA 4AYKA 1ASTA 966CA 1AKLA 2D1OA 1QIAA 2DW0A 3LQ0A 2L0RA 5I12A 2TCLA 3VTGA 2OY4A 3RTTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2O36 A;  2X3B A;  3ZVS A;  3K7N A;  4WZV A;  5I43 A;  1YOU A;  2OY2 A;  1XUD A;  3F17 A;  4GWN A;  1ZXC A;  1QIB A;  4AUO A;  1I1I P;  4WF6 A;  4HMA A;  1G05 A;  4FU4 A;  3O2X A;  1JAP A;  4ZR5 A;  4DD8 A;  3AYK A;  5BOY A;  3F15 A;  1JAO A;  3LJG A;  2Y6C A;  1GE5 A;  4DF9 A;  3HDB A;  3OHO A;  3B2Z A;  1D8F A;  4JPA A;  2AIG P;  1IAB A;  1H71 P;  3HY9 A;  1QUA A;  2W15 A;  1PWP A;  1GKD A;  3F18 A;  5L7F A;  5I2Z A;  3EWJ A;  1K7G A;  4H2E A;  2X3C A;  3UVC A;  3ZXH A;  1EUB A;  4AXQ A;  1R54 A;  3LKA A;  2MZE A;  3P1V A;  3KRY A;  1KUH A;  2USN A;  1R1I A;  3EDZ A;  1IAE A;  3EDI A;  2W12 A;  1C3I A;  2J0T A;  1YQY A;  4GUY A;  5CXA A;  1CAQ A;  1QJI A;  1UMS A;  1HTD A;  1I76 A;  1XUC A;  2O3E A;  1RM8 A;  1B8Y A;  4GR0 A;  1G12 A;  2OW0 A;  2RJP A;  1JK3 A;  5JMY A;  1JJ9 A;  1JKY A;  2OI0 A;  2WOA A;  1Y0V A;  2QPJ A;  3EHY A;  4GF1 A;  2K9C A;  4XCT A;  3I7G A;  1D5J A;  2V4B A;  2JT5 A;  1S4B P;  1OS9 A;  1K7Q A;  3U1R A;  3LMC A;  1C7K A;  3LJT A;  5CUH A;  3KEJ A;  4I03 A;  4EFS A;  2OVX A;  1PWQ A;  3LEA A;  1OM6 A;  2K2G A;  2OZR A;  2JNP A;  3N2V A;  2OW1 A;  4FVL A;  1DMT A;  2MZI A;  1G49 A;  2D1N A;  2YIG A;  1A85 A;  4GWM A;  5B5P A;  2OVZ A;  2X7M A;  1EB6 A;  1L6J A;  5D7W A;  1KUK A;  3ELM A;  1USN A;  2OXZ A;  4IN9 A;  2FV9 A;  1XFX A;  3NX7 A;  1O0Q A;  1QJJ A;  3CKI A;  1FM1 A;  3LIR A;  2AYK A;  4FXQ A;  1J7N A;  2KRJ A;  4GQL A;  4FXY P;  1G9K A;  4G0D A;  4H3X A;  4PKR A;  1DTH A;  1CGE A;  1MMR A;  1BQQ M;  4Q1L A;  5H8X A;  1KUG A;  4GR8 A;  4XBH A;  1YCM A;  1BZS A;  1HFS A;  2ERO A;  2FV5 A;  2RJQ A;  4WKE A;  3VI1 A;  3O64 A;  2CKI A;  3LQB A;  1MMB A;  4IJO A;  5D1U A;  2E3X A;  3OHL A;  1IAD A;  4GR3 A;  1CGF A;  4HX3 A;  3KWV C;  4DV8 A;  3KEC A;  2I47 A;  3K7L A;  1BQO A;  3AYU A;  4L63 A;  1JIZ A;  1FLS A;  1ZS0 A;  1SLM A;  1IAA A;  3F1A A;  2MLS A;  1GO8 P;  3TT4 A;  2JSD A;  1D8M A;  1ZXV A;  2PJT A;  1UEA A;  3SHI A;  3B92 A;  1ZTQ A;  2MZH A;  4I35 A;  3WV3 A;  1MMP A;  3DSL A;  5D1T A;  4H76 A;  2DDF A;  1OS2 A;  3I7I A;  4L19 A;  1AF0 A;  1JAQ A;  3LIL A;  5D2B A;  1A86 A;  1BKC E;  5D3C A;  4L6T A;  3LUM A;  4H84 A;  3V96 B;  1BIW A;  3TVC A;  4PKT A;  2W13 A;  1SU3 A;  1R1J A;  4JA1 A;  1SRP A;  5D1S A;  1OMJ A;  2SRT A;  1XFZ A;  2OW9 A;  1HY7 A;  1HOV A;  1C8T A;  1BUD A;  1SMP A;  1UTZ A;  2Z2D A;  3L0T A;  3LJZ A;  1MMQ A;  1WNI A;  1MNC A;  1GE6 A;  1R1H A;  1UTT A;  3RTS A;  3USN A;  2CLT A;  3DNG A;  1G4K A;  3G5C A;  4PKS A;  3GBO A;  2W0D A;  4A3W A;  1B3D A;  5I4O A;  3TSK A;  2ERQ A;  1KBC A;  1ATL A;  1AYK A;  1QIC A;  1GE7 A;  4A7B A;  1PWU A;  1Z3J A;  1BM6 A;  3LUN A;  3BA0 A;  2WO9 A;  1JH1 A;  1CIZ A;  2MLR A;  3Q2H A;  3HB2 P;  1XFU A;  1HV5 A;  1ROS A;  3HDA P;  2E2D A;  2W14 A;  3EDH A;  1PWV A;  2OW2 A;  1Y8J A;  2XS4 A;  1BSW A;  1R55 A;  830C A;  4WK7 A;  3TS4 A;  1GO7 P;  1XFY A;  2ERP A;  1XFW A;  3HBU P;  2J83 A;  3ZUK A;  2JIH A;  4JQG A;  3LGP A;  4IUW A;  1XUR A;  4XM7 A;  4H1Q A;  2POJ A;  4H49 A;  1CK7 A;  3EDG A;  2Y6D A;  4WKI A;  1KAP P;  1BKC A;  3DWB A;  2YB9 A;  2DW2 A;  4R3V A;  2XS3 A;  3WV2 A;  3F16 A;  3L0V A;  1CGL A;  4AIG A;  4H30 A;  5L79 A;  3LK8 A;  4XM6 A;  2A8H A;  5CZM A;  1FBL A;  4PKQ A;  1OM8 A;  3HYG A;  3WV1 A;  3DL1 A;  1ND1 A;  1Q3A A;  2X3A A;  3DPF A;  4ON1 A;  3KEK A;  1RMZ A;  2JT6 A;  3HY7 A;  1EAK A;  1XFV A;  1CXV A;  3DPE A;  1IAG A;  5BPA A;  3E8R A;  3P24 A;  456C A;  3Q2G A;  4PKV A;  4H82 A;  3KMC A;  1I73 A;  1D7X A;  1IAC A;  3LIK A;  1Y93 A;  1JIW P;  4XM8 A;  4DPE A;  2DDY A;  2OXU A;  4JP4 A;  1PWW A;  4ILW D;  1BUV M;  1SAT A;  1ZVX A;  1K7I A;  3B8Z A;  1ZP5 A;  2WO8 A;  1HFC A;  4JIJ A;  5BOT A;  3EHX A;  3HBV P;  1YP1 A;  3KHI A;  1KUI A;  1UMT A;  2DW1 A;  4PKU A;  4CTH A;  3LE9 A;  5I3M A;  2HU6 A;  5B5O A;  3MA2 A;  1JAN A;  3KME A;  3F19 A;  2OXW A;  1CQR A;  1OM7 A;  1BKC I;  1GXD A;  1O0T A;  2N8R A;  1KUF A;  1OO9 A;  4J4M A;  5LAB A;  4PKW A;  1GKC A;  3AIG A;  4G9L A;  4QKZ A;  3N2U A;  5I0L A;  3G42 A;  1SLN A;  4AYK A;  1AST A;  966C A;  1AKL A;  2D1O A;  1QIA A;  2DW0 A;  3LQ0 A;  2L0R A;  5I12 A;  2TCL A;  3VTG A;  2OY4 A;  3RTT A; 
#chains in the Genus database with same CATH topology
 2O36 A;  2X3B A;  3ZVS A;  3K7N A;  4WZV A;  5I43 A;  1YOU A;  2OY2 A;  1XUD A;  3F17 A;  4GWN A;  1ZXC A;  1QIB A;  4AUO A;  1I1I P;  4WF6 A;  4HMA A;  1G05 A;  4FU4 A;  3O2X A;  1JAP A;  4ZR5 A;  4DD8 A;  3AYK A;  5BOY A;  3F15 A;  1JAO A;  3LJG A;  2Y6C A;  1GE5 A;  4DF9 A;  3HDB A;  3OHO A;  3B2Z A;  1D8F A;  4JPA A;  2AIG P;  1IAB A;  1H71 P;  3HY9 A;  1QUA A;  2W15 A;  1PWP A;  1GKD A;  3F18 A;  5L7F A;  5I2Z A;  3EWJ A;  1K7G A;  4H2E A;  2X3C A;  3UVC A;  3ZXH A;  1EUB A;  4AXQ A;  1R54 A;  3LKA A;  2MZE A;  3P1V A;  3KRY A;  1KUH A;  2USN A;  1R1I A;  3EDZ A;  1IAE A;  3EDI A;  2W12 A;  1C3I A;  2J0T A;  1YQY A;  4GUY A;  5CXA A;  1CAQ A;  1QJI A;  1UMS A;  1HTD A;  1I76 A;  1XUC A;  2O3E A;  1RM8 A;  1B8Y A;  4GR0 A;  1G12 A;  2OW0 A;  2RJP A;  1JK3 A;  5JMY A;  1JJ9 A;  1JKY A;  2OI0 A;  2WOA A;  1Y0V A;  2QPJ A;  3EHY A;  4GF1 A;  2K9C A;  4XCT A;  3I7G A;  1D5J A;  3DTE A;  2V4B A;  2JT5 A;  1S4B P;  1OS9 A;  1K7Q A;  3U1R A;  3LMC A;  1C7K A;  3LJT A;  5CUH A;  3KEJ A;  4I03 A;  4EFS A;  2OVX A;  1PWQ A;  3LEA A;  1OM6 A;  2K2G A;  2OZR A;  2JNP A;  3N2V A;  2OW1 A;  4FVL A;  1DMT A;  2MZI A;  1G49 A;  2D1N A;  2YIG A;  1A85 A;  4GWM A;  5B5P A;  2OVZ A;  2X7M A;  1EB6 A;  1L6J A;  5D7W A;  1KUK A;  3ELM A;  1USN A;  2OXZ A;  1XAX A;  4IN9 A;  2FV9 A;  1XFX A;  3NX7 A;  1O0Q A;  1QJJ A;  3CKI A;  1FM1 A;  3LIR A;  2AYK A;  4FXQ A;  1J7N A;  2KRJ A;  4GQL A;  4FXY P;  3DTK A;  1G9K A;  4G0D A;  4H3X A;  2YUF A;  4PKR A;  1DTH A;  1CGE A;  1MMR A;  1BQQ M;  4Q1L A;  5H8X A;  1KUG A;  4GR8 A;  4XBH A;  1YCM A;  3DTI A;  1BZS A;  1HFS A;  2ERO A;  2FV5 A;  2RJQ A;  4WKE A;  3VI1 A;  3O64 A;  2CKI A;  3LQB A;  1MMB A;  4IJO A;  5D1U A;  2E3X A;  3OHL A;  1IAD A;  4GR3 A;  1CGF A;  4HX3 A;  3KWV C;  4DV8 A;  3KEC A;  2I47 A;  3K7L A;  1BQO A;  3AYU A;  4L63 A;  1JIZ A;  1FLS A;  1ZS0 A;  1SLM A;  1IAA A;  3F1A A;  2MLS A;  1GO8 P;  3TT4 A;  2JSD A;  1D8M A;  1ZXV A;  2PJT A;  1UEA A;  3SHI A;  3B92 A;  1ZTQ A;  2MZH A;  1TVI A;  4I35 A;  3WV3 A;  1MMP A;  3DSL A;  5D1T A;  4H76 A;  2DDF A;  1OS2 A;  3I7I A;  4L19 A;  1AF0 A;  1JAQ A;  3LIL A;  5D2B A;  1A86 A;  1BKC E;  5D3C A;  4L6T A;  3LUM A;  4H84 A;  3V96 B;  1BIW A;  3TVC A;  4PKT A;  2W13 A;  1SU3 A;  1R1J A;  4JA1 A;  1SRP A;  5D1S A;  1OMJ A;  2SRT A;  1XFZ A;  2OW9 A;  1HY7 A;  1HOV A;  1C8T A;  1BUD A;  1SMP A;  1UTZ A;  2Z2D A;  3L0T A;  3LJZ A;  1MMQ A;  1WNI A;  1MNC A;  1GE6 A;  1R1H A;  1UTT A;  3RTS A;  3USN A;  2CLT A;  3DNG A;  1G4K A;  3G5C A;  4PKS A;  3GBO A;  2W0D A;  4A3W A;  1B3D A;  5I4O A;  3TSK A;  2ERQ A;  1KBC A;  1ATL A;  1AYK A;  1QIC A;  1GE7 A;  4A7B A;  1PWU A;  1Z3J A;  1BM6 A;  3LUN A;  3BA0 A;  2WO9 A;  1JH1 A;  1CIZ A;  2MLR A;  3Q2H A;  3HB2 P;  1XFU A;  1HV5 A;  1ROS A;  3HDA P;  2E2D A;  2W14 A;  3EDH A;  1PWV A;  2OW2 A;  1Y8J A;  2XS4 A;  1BSW A;  1R55 A;  830C A;  4WK7 A;  3TS4 A;  1GO7 P;  1XFY A;  2ERP A;  1XFW A;  3HBU P;  2J83 A;  3ZUK A;  2JIH A;  4JQG A;  3LGP A;  4IUW A;  1XUR A;  4XM7 A;  4H1Q A;  2POJ A;  4H49 A;  1CK7 A;  3EDG A;  2Y6D A;  4WKI A;  1KAP P;  1BKC A;  3DWB A;  2YB9 A;  2DW2 A;  4R3V A;  2XS3 A;  3WV2 A;  3F16 A;  3L0V A;  1CGL A;  4AIG A;  4H30 A;  5L79 A;  3LK8 A;  4XM6 A;  2A8H A;  5CZM A;  1FBL A;  4PKQ A;  1OM8 A;  3HYG A;  3WV1 A;  3DL1 A;  1ND1 A;  1Q3A A;  2X3A A;  3DPF A;  4ON1 A;  3KEK A;  1RMZ A;  2JT6 A;  3HY7 A;  1EAK A;  1XFV A;  1CXV A;  3DPE A;  1IAG A;  5BPA A;  3E8R A;  3P24 A;  456C A;  3Q2G A;  4PKV A;  4H82 A;  3KMC A;  1I73 A;  1D7X A;  1IAC A;  3LIK A;  1Y93 A;  1JIW P;  4XM8 A;  4DPE A;  2DDY A;  4L7A A;  2OXU A;  4JP4 A;  1PWW A;  4ILW D;  1BUV M;  1SAT A;  1ZVX A;  1K7I A;  3B8Z A;  1ZP5 A;  2WO8 A;  1HFC A;  4JIJ A;  5BOT A;  3EHX A;  3HBV P;  1YP1 A;  3KHI A;  1KUI A;  1UMT A;  2DW1 A;  4PKU A;  4CTH A;  3LE9 A;  5I3M A;  2HU6 A;  5B5O A;  3MA2 A;  1JAN A;  3KME A;  3F19 A;  2OXW A;  1CQR A;  1OM7 A;  1BKC I;  1GXD A;  1O0T A;  2N8R A;  1KUF A;  1OO9 A;  4J4M A;  5LAB A;  4PKW A;  1GKC A;  3AIG A;  4G9L A;  4QKZ A;  3N2U A;  5I0L A;  3G42 A;  1XM5 A;  1SLN A;  1OZ9 A;  4AYK A;  1AST A;  966C A;  1AKL A;  2D1O A;  1QIA A;  2DW0 A;  3LQ0 A;  2L0R A;  5I12 A;  2TCL A;  3VTG A;  2OY4 A;  3RTT A; 
#chains in the Genus database with same CATH homology
 2O36 A;  2X3B A;  3ZVS A;  3K7N A;  4WZV A;  5I43 A;  1YOU A;  2OY2 A;  1XUD A;  3F17 A;  4GWN A;  1ZXC A;  1QIB A;  4AUO A;  1I1I P;  4WF6 A;  4HMA A;  1G05 A;  4FU4 A;  3O2X A;  1JAP A;  4ZR5 A;  4DD8 A;  3AYK A;  5BOY A;  3F15 A;  1JAO A;  3LJG A;  2Y6C A;  1GE5 A;  4DF9 A;  3HDB A;  3OHO A;  3B2Z A;  1D8F A;  4JPA A;  2AIG P;  1IAB A;  1H71 P;  3HY9 A;  1QUA A;  2W15 A;  1PWP A;  1GKD A;  3F18 A;  5L7F A;  5I2Z A;  3EWJ A;  1K7G A;  4H2E A;  2X3C A;  3UVC A;  3ZXH A;  1EUB A;  4AXQ A;  1R54 A;  3LKA A;  2MZE A;  3P1V A;  3KRY A;  1KUH A;  2USN A;  1R1I A;  3EDZ A;  1IAE A;  3EDI A;  2W12 A;  1C3I A;  2J0T A;  1YQY A;  4GUY A;  5CXA A;  1CAQ A;  1QJI A;  1UMS A;  1HTD A;  1I76 A;  1XUC A;  2O3E A;  1RM8 A;  1B8Y A;  4GR0 A;  1G12 A;  2OW0 A;  2RJP A;  1JK3 A;  5JMY A;  1JJ9 A;  1JKY A;  2OI0 A;  2WOA A;  1Y0V A;  2QPJ A;  3EHY A;  4GF1 A;  2K9C A;  4XCT A;  3I7G A;  1D5J A;  3DTE A;  2V4B A;  2JT5 A;  1S4B P;  1OS9 A;  1K7Q A;  3U1R A;  3LMC A;  1C7K A;  3LJT A;  5CUH A;  3KEJ A;  4I03 A;  4EFS A;  2OVX A;  1PWQ A;  3LEA A;  1OM6 A;  2K2G A;  2OZR A;  2JNP A;  3N2V A;  2OW1 A;  4FVL A;  1DMT A;  2MZI A;  1G49 A;  2D1N A;  2YIG A;  1A85 A;  4GWM A;  5B5P A;  2OVZ A;  2X7M A;  1EB6 A;  1L6J A;  5D7W A;  1KUK A;  3ELM A;  1USN A;  2OXZ A;  4IN9 A;  2FV9 A;  1XFX A;  3NX7 A;  1O0Q A;  1QJJ A;  3CKI A;  1FM1 A;  3LIR A;  2AYK A;  4FXQ A;  1J7N A;  2KRJ A;  4GQL A;  4FXY P;  3DTK A;  1G9K A;  4G0D A;  4H3X A;  2YUF A;  4PKR A;  1DTH A;  1CGE A;  1MMR A;  1BQQ M;  4Q1L A;  5H8X A;  1KUG A;  4GR8 A;  4XBH A;  1YCM A;  3DTI A;  1BZS A;  1HFS A;  2ERO A;  2FV5 A;  2RJQ A;  4WKE A;  3VI1 A;  3O64 A;  2CKI A;  3LQB A;  1MMB A;  4IJO A;  5D1U A;  2E3X A;  3OHL A;  1IAD A;  4GR3 A;  1CGF A;  4HX3 A;  3KWV C;  4DV8 A;  3KEC A;  2I47 A;  3K7L A;  1BQO A;  3AYU A;  4L63 A;  1JIZ A;  1FLS A;  1ZS0 A;  1SLM A;  1IAA A;  3F1A A;  2MLS A;  1GO8 P;  3TT4 A;  2JSD A;  1D8M A;  1ZXV A;  2PJT A;  1UEA A;  3SHI A;  3B92 A;  1ZTQ A;  2MZH A;  4I35 A;  3WV3 A;  1MMP A;  3DSL A;  5D1T A;  4H76 A;  2DDF A;  1OS2 A;  3I7I A;  4L19 A;  1AF0 A;  1JAQ A;  3LIL A;  5D2B A;  1A86 A;  1BKC E;  5D3C A;  4L6T A;  3LUM A;  4H84 A;  3V96 B;  1BIW A;  3TVC A;  4PKT A;  2W13 A;  1SU3 A;  1R1J A;  4JA1 A;  1SRP A;  5D1S A;  1OMJ A;  2SRT A;  1XFZ A;  2OW9 A;  1HY7 A;  1HOV A;  1C8T A;  1BUD A;  1SMP A;  1UTZ A;  2Z2D A;  3L0T A;  3LJZ A;  1MMQ A;  1WNI A;  1MNC A;  1GE6 A;  1R1H A;  1UTT A;  3RTS A;  3USN A;  2CLT A;  3DNG A;  1G4K A;  3G5C A;  4PKS A;  3GBO A;  2W0D A;  4A3W A;  1B3D A;  5I4O A;  3TSK A;  2ERQ A;  1KBC A;  1ATL A;  1AYK A;  1QIC A;  1GE7 A;  4A7B A;  1PWU A;  1Z3J A;  1BM6 A;  3LUN A;  3BA0 A;  2WO9 A;  1JH1 A;  1CIZ A;  2MLR A;  3Q2H A;  3HB2 P;  1XFU A;  1HV5 A;  1ROS A;  3HDA P;  2E2D A;  2W14 A;  3EDH A;  1PWV A;  2OW2 A;  1Y8J A;  2XS4 A;  1BSW A;  1R55 A;  830C A;  4WK7 A;  3TS4 A;  1GO7 P;  1XFY A;  2ERP A;  1XFW A;  3HBU P;  2J83 A;  3ZUK A;  2JIH A;  4JQG A;  3LGP A;  4IUW A;  1XUR A;  4XM7 A;  4H1Q A;  2POJ A;  4H49 A;  1CK7 A;  3EDG A;  2Y6D A;  4WKI A;  1KAP P;  1BKC A;  3DWB A;  2YB9 A;  2DW2 A;  4R3V A;  2XS3 A;  3WV2 A;  3F16 A;  3L0V A;  1CGL A;  4AIG A;  4H30 A;  5L79 A;  3LK8 A;  4XM6 A;  2A8H A;  5CZM A;  1FBL A;  4PKQ A;  1OM8 A;  3HYG A;  3WV1 A;  3DL1 A;  1ND1 A;  1Q3A A;  2X3A A;  3DPF A;  4ON1 A;  3KEK A;  1RMZ A;  2JT6 A;  3HY7 A;  1EAK A;  1XFV A;  1CXV A;  3DPE A;  1IAG A;  5BPA A;  3E8R A;  3P24 A;  456C A;  3Q2G A;  4PKV A;  4H82 A;  3KMC A;  1I73 A;  1D7X A;  1IAC A;  3LIK A;  1Y93 A;  1JIW P;  4XM8 A;  4DPE A;  2DDY A;  4L7A A;  2OXU A;  4JP4 A;  1PWW A;  4ILW D;  1BUV M;  1SAT A;  1ZVX A;  1K7I A;  3B8Z A;  1ZP5 A;  2WO8 A;  1HFC A;  4JIJ A;  5BOT A;  3EHX A;  3HBV P;  1YP1 A;  3KHI A;  1KUI A;  1UMT A;  2DW1 A;  4PKU A;  4CTH A;  3LE9 A;  5I3M A;  2HU6 A;  5B5O A;  3MA2 A;  1JAN A;  3KME A;  3F19 A;  2OXW A;  1CQR A;  1OM7 A;  1BKC I;  1GXD A;  1O0T A;  2N8R A;  1KUF A;  1OO9 A;  4J4M A;  5LAB A;  4PKW A;  1GKC A;  3AIG A;  4G9L A;  4QKZ A;  3N2U A;  5I0L A;  3G42 A;  1SLN A;  4AYK A;  1AST A;  966C A;  1AKL A;  2D1O A;  1QIA A;  2DW0 A;  3LQ0 A;  2L0R A;  5I12 A;  2TCL A;  3VTG A;  2OY4 A;  3RTT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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