3NX7A

Crystal structure of the catalytic domain of human mmp12 complexed with the inhibitor n-hydroxy-2-(n-(2-hydroxyethyl)4-methoxyphenylsulfonamido)acetamide
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
158
structure length
158
Chain Sequence
GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Exploring the subtleties of drug-receptor interactions: the case of matrix metalloproteinases
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Macrophage metalloelastase
total genus 43
structure length 158
sequence length 158
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2010-07-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3nx7A00
3LJGA 2K2GA 3USNA 5L7FA 3F15A 2MZHA 2QPJA 2O3EA 2YIGA 2OZRA 3B8ZA 2AIGP 1PWUA 2OVZA 1BM6A 2I47A 1G05A 3I7IA 1SLNA 4HX3A 3HYGA 1Y8JA 4QKZA 1GO8P 3F17A 5I0LA 3BA0A 1ZS0A 3HY7A 3P24A 1R54A 3DPEA 1KAPP 3N2VA 3VI1A 1QIAA 4DPEA 3I7GA 2X3BA 4XM6A 2W14A 5B5PA 3EDIA 2MZEA 1PWWA 2EROA 2OW1A 2N8RA 2SRTA 4FU4A 1OO9A 4GQLA 1R1IA 2V4BA 4I35A 966CA 3KEKA 3DNGA 5I2ZA 3TT4A 1OM6A 4IUWA 4ZR5A 5I3MA 2RJPA 4IN9A 3KECA 1B8YA 1ZXCA 3RTTA 2AYKA 2WO9A 5D1SA 1A85A 2XS3A 4XM8A 3Q2HA 1JJ9A 1WNIA 4H49A 4H82A 2ERPA 2FV9A 1QJIA 3LUNA 3SHIA 4PKWA 1QUAA 1XFUA 1IAEA 2DW1A 2TCLA 2OI0A 1D8FA 5CXAA 4WF6A 5B5OA 3P1VA 1D5JA 1HFSA 1O0TA 4CTHA 1C3IA 3TSKA 5D1UA 4PKVA 4GWMA 3ZXHA 4A3WA 1USNA 1OM7A 1XFVA 3CKIA 2DW0A 1QJJA 1AF0A 1HY7A 1UMSA 2X7MA 3KWVC 1KUIA 1JKYA 2A8HA 1R1JA 4R3VA 2RJQA 1QIBA 1ZP5A 4H76A 2W13A 1OM8A 1OMJA 456CA 1K7IA 3LEAA 2E3XA 2OXUA 1QICA 4WZVA 3LJZA 2Y6CA 2YB9A 4DD8A 4GF1A 1H71P 1AYKA 1DMTA 2OW9A 2OVXA 4L6TA 4XBHA 5H8XA 3KMEA 1K7GA 1XUDA 2JT5A 3O64A 1UEAA 1SU3A 4JIJA 3U1RA 3EHXA 4L19A 1EB6A 1IAGA 1G9KA 3HDBA 1K7QA 2J0TA 2Z2DA 2K9CA 3KRYA 1UTZA 1SMPA 3DSLA 1BZSA 2USNA 5I43A 1GE7A 4GR8A 2PJTA 1PWPA 1D8MA 5LABA 2X3CA 4FXQA 3OHLA 3F19A 1IAAA 2JT6A 1GO7P 3G42A 3V96B 3ZUKA 1BQOA 1I1IP 3B2ZA 3HY9A 5L79A 1ZXVA 1FM1A 2MLRA 3TS4A 4DV8A 5I12A 3DWBA 5CUHA 1BKCE 5BOTA 3NX7A 2CLTA 1O0QA 2Y6DA 3AIGA 3E8RA 1XUCA 3K7NA 3LE9A 1CGEA 3F1AA 1BQQM 2XS4A 2OXZA 1GXDA 1KBCA 4GR3A 4I03A 4AXQA 4J4MA 4FXYP 1YQYA 1KUGA 3L0VA 3GBOA 4G0DA 4XM7A 3LIRA 1ZVXA 1SATA 4GUYA 1RM8A 4H3XA 4EFSA 1BSWA 3EDGA 3LGPA 1ASTA 1G4KA 3LQ0A 3LQBA 3O2XA 4AYKA 4XCTA 2JSDA 2JIHA 1BKCA 3LJTA 1Y0VA 1L6JA 4A7BA 4L63A 1EAKA 3DPFA 1HTDA 3OHOA 1XURA 1HFCA 3F18A 3LUMA 830CA 1CAQA 4Q1LA 3LKAA 3LK8A 2CKIA 1JH1A 1Q3AA 1BKCI 1GKCA 5JMYA 1CQRA 1B3DA 1GE5A 3LILA 3AYKA 1UTTA 1IABA 2FV5A 2L0RA 1ND1A 1UMTA 4PKUA 1BUVM 3AYUA 1HOVA 1I73A 2W12A 4WKEA 1J7NA 1DTHA 3MA2A 3WV1A 2X3AA 3F16A 2OW0A 2D1NA 3Q2GA 1JAPA 1ZTQA 5D7WA 1XFYA 1IACA 1JIWP 3VTGA 5I4OA 5D1TA 3WV2A 1Y93A 3RTSA 1D7XA 1MMRA 4ON1A 4GR0A 1MMQA 4PKQA 3B92A 1BIWA 4PKRA 4AIGA 1IADA 4IJOA 1JIZA 3EHYA 1BUDA 1G49A 3HBVP 2WOAA 4FVLA 3HDAP 1RMZA 4WK7A 3DL1A 1KUHA 3LMCA 3EDHA 5D3CA 2W15A 2W0DA 1PWVA 1JAOA 4G9LA 4JP4A 2DDFA 2POJA 4PKSA 1MMPA 3HB2P 3UVCA 2MLSA 3L0TA 2O36A 2OY4A 1XFWA 4H84A 1EUBA 1KUKA 4JQGA 1R1HA 1CGLA 2OXWA 4AUOA 2DDYA 2OY2A 3LIKA 3EWJA 4GWNA 1ATLA 5CZMA 3KHIA 1I76A 3G5CA 5BPAA 4JPAA 1FBLA 1HV5A 3HBUP 1MMBA 1SRPA 2JNPA 1CIZA 1GKDA 1XFZA 2HU6A 2KRJA 3KEJA 1MNCA 2D1OA 4H30A 1R55A 5D2BA 1JANA 1YOUA 1XFXA 1OS9A 4H2EA 3N2UA 4H1QA 4HMAA 1JK3A 1Z3JA 1PWQA 5BOYA 4WKIA 1C7KA 3ELMA 1SLMA 1KUFA 1JAQA 3EDZA 1A86A 1G12A 3K7LA 1AKLA 1ROSA 2MZIA 2E2DA 4ILWD 1CK7A 1C8TA 1YCMA 2J83A 1OS2A 3WV3A 1YP1A 1S4BP 2WO8A 3KMCA 2ERQA 1FLSA 3TVCA 1CGFA 1CXVA 2OW2A 4DF9A 4JA1A 2DW2A 4PKTA 3ZVSA 1GE6A
chains in the Genus database with same CATH superfamily
3LJGA 2K2GA 3USNA 1OZ9A 5L7FA 3F15A 2MZHA 2QPJA 2O3EA 2YIGA 2OZRA 3B8ZA 2AIGP 1PWUA 2OVZA 1BM6A 2I47A 1G05A 3I7IA 1SLNA 4HX3A 3HYGA 1Y8JA 4QKZA 1GO8P 3F17A 5I0LA 3BA0A 1ZS0A 3HY7A 3P24A 1R54A 3DPEA 1KAPP 3N2VA 3VI1A 1QIAA 4DPEA 3I7GA 2X3BA 4XM6A 2W14A 5B5PA 3EDIA 2MZEA 1PWWA 2EROA 2OW1A 2N8RA 2SRTA 4FU4A 1OO9A 4GQLA 1R1IA 2V4BA 4I35A 966CA 3KEKA 3DNGA 5I2ZA 3TT4A 1OM6A 4IUWA 4ZR5A 5I3MA 2RJPA 4IN9A 3KECA 1B8YA 1ZXCA 3RTTA 1XM5A 2AYKA 2WO9A 5D1SA 1A85A 2XS3A 4XM8A 3Q2HA 1JJ9A 1WNIA 4H49A 4H82A 2ERPA 2FV9A 1QJIA 3LUNA 3SHIA 4PKWA 1QUAA 1XFUA 1IAEA 2DW1A 2TCLA 3DTIA 2OI0A 1D8FA 5CXAA 4WF6A 5B5OA 3P1VA 1D5JA 1HFSA 1O0TA 4CTHA 1C3IA 3TSKA 5D1UA 4PKVA 4GWMA 3ZXHA 4A3WA 1USNA 1OM7A 1XFVA 3CKIA 2DW0A 1QJJA 1AF0A 1HY7A 1UMSA 2X7MA 3KWVC 1KUIA 1JKYA 2A8HA 1R1JA 4R3VA 2RJQA 1QIBA 1ZP5A 4H76A 2W13A 1OM8A 1OMJA 456CA 1K7IA 3LEAA 2E3XA 2OXUA 1QICA 4WZVA 3LJZA 2Y6CA 2YB9A 4DD8A 4GF1A 1H71P 1AYKA 1DMTA 2OW9A 2OVXA 4L6TA 4XBHA 5H8XA 3KMEA 3DTEA 1K7GA 1XUDA 2JT5A 3O64A 1UEAA 1SU3A 4JIJA 3U1RA 3EHXA 4L19A 1EB6A 1IAGA 1G9KA 3HDBA 1K7QA 2J0TA 2Z2DA 2K9CA 3KRYA 1UTZA 1SMPA 3DSLA 1BZSA 2USNA 5I43A 1GE7A 4GR8A 2PJTA 1PWPA 1D8MA 5LABA 2X3CA 4FXQA 3OHLA 3F19A 1IAAA 2JT6A 1GO7P 3G42A 3V96B 3ZUKA 1BQOA 1I1IP 3B2ZA 3HY9A 5L79A 1ZXVA 1FM1A 2MLRA 3TS4A 4DV8A 5I12A 3DWBA 5CUHA 1BKCE 5BOTA 3NX7A 2CLTA 1O0QA 2Y6DA 3AIGA 3E8RA 1XUCA 3K7NA 3LE9A 1CGEA 3F1AA 1BQQM 2XS4A 2OXZA 1GXDA 1KBCA 4GR3A 4I03A 4AXQA 4J4MA 4FXYP 1YQYA 1KUGA 3L0VA 3GBOA 4G0DA 4XM7A 3LIRA 1ZVXA 1SATA 4GUYA 1RM8A 4H3XA 4EFSA 1BSWA 3EDGA 3LGPA 1ASTA 1G4KA 3LQ0A 3LQBA 3O2XA 4AYKA 4XCTA 2JSDA 2JIHA 1BKCA 3LJTA 1Y0VA 1L6JA 4A7BA 4L63A 1EAKA 3DPFA 1HTDA 3OHOA 1XURA 1HFCA 3F18A 3LUMA 830CA 1CAQA 4Q1LA 3LKAA 3LK8A 2CKIA 1JH1A 1Q3AA 1BKCI 1GKCA 5JMYA 1CQRA 1B3DA 1GE5A 3LILA 3AYKA 1UTTA 1XAXA 1IABA 2FV5A 2L0RA 1ND1A 1TVIA 1UMTA 4PKUA 1BUVM 3AYUA 2YUFA 1HOVA 1I73A 2W12A 4WKEA 1J7NA 1DTHA 3MA2A 3WV1A 2X3AA 3F16A 2OW0A 2D1NA 3Q2GA 1JAPA 1ZTQA 5D7WA 1XFYA 1IACA 1JIWP 3VTGA 5I4OA 5D1TA 3WV2A 1Y93A 4L7AA 3RTSA 1D7XA 1MMRA 4ON1A 4GR0A 1MMQA 4PKQA 3B92A 1BIWA 3DTKA 4PKRA 4AIGA 1IADA 4IJOA 1JIZA 3EHYA 1BUDA 1G49A 3HBVP 2WOAA 4FVLA 3HDAP 1RMZA 4WK7A 3DL1A 1KUHA 3LMCA 3EDHA 5D3CA 2W15A 2W0DA 1PWVA 1JAOA 4G9LA 4JP4A 2DDFA 2POJA 4PKSA 1MMPA 3HB2P 3UVCA 2MLSA 3L0TA 2O36A 2OY4A 1XFWA 4H84A 1EUBA 1KUKA 4JQGA 1R1HA 1CGLA 2OXWA 4AUOA 2DDYA 2OY2A 3LIKA 3EWJA 4GWNA 1ATLA 5CZMA 3KHIA 1I76A 3G5CA 5BPAA 4JPAA 1FBLA 1HV5A 3HBUP 1MMBA 1SRPA 2JNPA 1CIZA 1GKDA 1XFZA 2HU6A 2KRJA 3KEJA 1MNCA 2D1OA 4H30A 1R55A 5D2BA 1JANA 1YOUA 1XFXA 1OS9A 4H2EA 3N2UA 4H1QA 4HMAA 1JK3A 1Z3JA 1PWQA 5BOYA 4WKIA 1C7KA 3ELMA 1SLMA 1KUFA 1JAQA 3EDZA 1A86A 1G12A 3K7LA 1AKLA 1ROSA 2MZIA 2E2DA 4ILWD 1CK7A 1C8TA 1YCMA 2J83A 1OS2A 3WV3A 1YP1A 1S4BP 2WO8A 3KMCA 2ERQA 1FLSA 3TVCA 1CGFA 1CXVA 2OW2A 4DF9A 4JA1A 2DW2A 4PKTA 3ZVSA 1GE6A
chains in the Genus database with same CATH topology
3LJGA 2K2GA 3USNA 5L7FA 3F15A 2MZHA 2QPJA 2O3EA 2YIGA 2OZRA 3B8ZA 2AIGP 1PWUA 2OVZA 1BM6A 2I47A 1G05A 3I7IA 1SLNA 4HX3A 3HYGA 1Y8JA 4QKZA 1GO8P 3F17A 5I0LA 3BA0A 1ZS0A 3HY7A 3P24A 1R54A 3DPEA 1KAPP 3N2VA 3VI1A 1QIAA 4DPEA 3I7GA 2X3BA 4XM6A 2W14A 5B5PA 3EDIA 2MZEA 1PWWA 2EROA 2OW1A 2N8RA 2SRTA 4FU4A 1OO9A 4GQLA 1R1IA 2V4BA 4I35A 966CA 3KEKA 3DNGA 5I2ZA 3TT4A 1OM6A 4IUWA 4ZR5A 5I3MA 2RJPA 4IN9A 3KECA 1B8YA 1ZXCA 3RTTA 2AYKA 2WO9A 5D1SA 1A85A 2XS3A 4XM8A 3Q2HA 1JJ9A 1WNIA 4H49A 4H82A 2ERPA 2FV9A 1QJIA 3LUNA 3SHIA 4PKWA 1QUAA 1XFUA 1IAEA 2DW1A 2TCLA 3DTIA 2OI0A 1D8FA 5CXAA 4WF6A 5B5OA 3P1VA 1D5JA 1HFSA 1O0TA 4CTHA 1C3IA 3TSKA 5D1UA 4PKVA 4GWMA 3ZXHA 4A3WA 1USNA 1OM7A 1XFVA 3CKIA 2DW0A 1QJJA 1AF0A 1HY7A 1UMSA 2X7MA 3KWVC 1KUIA 1JKYA 2A8HA 1R1JA 4R3VA 2RJQA 1QIBA 1ZP5A 4H76A 2W13A 1OM8A 1OMJA 456CA 1K7IA 3LEAA 2E3XA 2OXUA 1QICA 4WZVA 3LJZA 2Y6CA 2YB9A 4DD8A 4GF1A 1H71P 1AYKA 1DMTA 2OW9A 2OVXA 4L6TA 4XBHA 5H8XA 3KMEA 3DTEA 1K7GA 1XUDA 2JT5A 3O64A 1UEAA 1SU3A 4JIJA 3U1RA 3EHXA 4L19A 1EB6A 1IAGA 1G9KA 3HDBA 1K7QA 2J0TA 2Z2DA 2K9CA 3KRYA 1UTZA 1SMPA 3DSLA 1BZSA 2USNA 5I43A 1GE7A 4GR8A 2PJTA 1PWPA 1D8MA 5LABA 2X3CA 4FXQA 3OHLA 3F19A 1IAAA 2JT6A 1GO7P 3G42A 3V96B 3ZUKA 1BQOA 1I1IP 3B2ZA 3HY9A 5L79A 1ZXVA 1FM1A 2MLRA 3TS4A 4DV8A 5I12A 3DWBA 5CUHA 1BKCE 5BOTA 3NX7A 2CLTA 1O0QA 2Y6DA 3AIGA 3E8RA 1XUCA 3K7NA 3LE9A 1CGEA 3F1AA 1BQQM 2XS4A 2OXZA 1GXDA 1KBCA 4GR3A 4I03A 4AXQA 4J4MA 4FXYP 1YQYA 1KUGA 3L0VA 3GBOA 4G0DA 4XM7A 3LIRA 1ZVXA 1SATA 4GUYA 1RM8A 4H3XA 4EFSA 1BSWA 3EDGA 3LGPA 1ASTA 1G4KA 3LQ0A 3LQBA 3O2XA 4AYKA 4XCTA 2JSDA 2JIHA 1BKCA 3LJTA 1Y0VA 1L6JA 4A7BA 4L63A 1EAKA 3DPFA 1HTDA 3OHOA 1XURA 1HFCA 3F18A 3LUMA 830CA 1CAQA 4Q1LA 3LKAA 3LK8A 2CKIA 1JH1A 1Q3AA 1BKCI 1GKCA 5JMYA 1CQRA 1B3DA 1GE5A 3LILA 3AYKA 1UTTA 1IABA 2FV5A 2L0RA 1ND1A 1UMTA 4PKUA 1BUVM 3AYUA 2YUFA 1HOVA 1I73A 2W12A 4WKEA 1J7NA 1DTHA 3MA2A 3WV1A 2X3AA 3F16A 2OW0A 2D1NA 3Q2GA 1JAPA 1ZTQA 5D7WA 1XFYA 1IACA 1JIWP 3VTGA 5I4OA 5D1TA 3WV2A 1Y93A 4L7AA 3RTSA 1D7XA 1MMRA 4ON1A 4GR0A 1MMQA 4PKQA 3B92A 1BIWA 3DTKA 4PKRA 4AIGA 1IADA 4IJOA 1JIZA 3EHYA 1BUDA 1G49A 3HBVP 2WOAA 4FVLA 3HDAP 1RMZA 4WK7A 3DL1A 1KUHA 3LMCA 3EDHA 5D3CA 2W15A 2W0DA 1PWVA 1JAOA 4G9LA 4JP4A 2DDFA 2POJA 4PKSA 1MMPA 3HB2P 3UVCA 2MLSA 3L0TA 2O36A 2OY4A 1XFWA 4H84A 1EUBA 1KUKA 4JQGA 1R1HA 1CGLA 2OXWA 4AUOA 2DDYA 2OY2A 3LIKA 3EWJA 4GWNA 1ATLA 5CZMA 3KHIA 1I76A 3G5CA 5BPAA 4JPAA 1FBLA 1HV5A 3HBUP 1MMBA 1SRPA 2JNPA 1CIZA 1GKDA 1XFZA 2HU6A 2KRJA 3KEJA 1MNCA 2D1OA 4H30A 1R55A 5D2BA 1JANA 1YOUA 1XFXA 1OS9A 4H2EA 3N2UA 4H1QA 4HMAA 1JK3A 1Z3JA 1PWQA 5BOYA 4WKIA 1C7KA 3ELMA 1SLMA 1KUFA 1JAQA 3EDZA 1A86A 1G12A 3K7LA 1AKLA 1ROSA 2MZIA 2E2DA 4ILWD 1CK7A 1C8TA 1YCMA 2J83A 1OS2A 3WV3A 1YP1A 1S4BP 2WO8A 3KMCA 2ERQA 1FLSA 3TVCA 1CGFA 1CXVA 2OW2A 4DF9A 4JA1A 2DW2A 4PKTA 3ZVSA 1GE6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LJG A;  2K2G A;  3USN A;  5L7F A;  3F15 A;  2MZH A;  2QPJ A;  2O3E A;  2YIG A;  2OZR A;  3B8Z A;  2AIG P;  1PWU A;  2OVZ A;  1BM6 A;  2I47 A;  1G05 A;  3I7I A;  1SLN A;  4HX3 A;  3HYG A;  1Y8J A;  4QKZ A;  1GO8 P;  3F17 A;  5I0L A;  3BA0 A;  1ZS0 A;  3HY7 A;  3P24 A;  1R54 A;  3DPE A;  1KAP P;  3N2V A;  3VI1 A;  1QIA A;  4DPE A;  3I7G A;  2X3B A;  4XM6 A;  2W14 A;  5B5P A;  3EDI A;  2MZE A;  1PWW A;  2ERO A;  2OW1 A;  2N8R A;  2SRT A;  4FU4 A;  1OO9 A;  4GQL A;  1R1I A;  2V4B A;  4I35 A;  966C A;  3KEK A;  3DNG A;  5I2Z A;  3TT4 A;  1OM6 A;  4IUW A;  4ZR5 A;  5I3M A;  2RJP A;  4IN9 A;  3KEC A;  1B8Y A;  1ZXC A;  3RTT A;  2AYK A;  2WO9 A;  5D1S A;  1A85 A;  2XS3 A;  4XM8 A;  3Q2H A;  1JJ9 A;  1WNI A;  4H49 A;  4H82 A;  2ERP A;  2FV9 A;  1QJI A;  3LUN A;  3SHI A;  4PKW A;  1QUA A;  1XFU A;  1IAE A;  2DW1 A;  2TCL A;  2OI0 A;  1D8F A;  5CXA A;  4WF6 A;  5B5O A;  3P1V A;  1D5J A;  1HFS A;  1O0T A;  4CTH A;  1C3I A;  3TSK A;  5D1U A;  4PKV A;  4GWM A;  3ZXH A;  4A3W A;  1USN A;  1OM7 A;  1XFV A;  3CKI A;  2DW0 A;  1QJJ A;  1AF0 A;  1HY7 A;  1UMS A;  2X7M A;  3KWV C;  1KUI A;  1JKY A;  2A8H A;  1R1J A;  4R3V A;  2RJQ A;  1QIB A;  1ZP5 A;  4H76 A;  2W13 A;  1OM8 A;  1OMJ A;  456C A;  1K7I A;  3LEA A;  2E3X A;  2OXU A;  1QIC A;  4WZV A;  3LJZ A;  2Y6C A;  2YB9 A;  4DD8 A;  4GF1 A;  1H71 P;  1AYK A;  1DMT A;  2OW9 A;  2OVX A;  4L6T A;  4XBH A;  5H8X A;  3KME A;  1K7G A;  1XUD A;  2JT5 A;  3O64 A;  1UEA A;  1SU3 A;  4JIJ A;  3U1R A;  3EHX A;  4L19 A;  1EB6 A;  1IAG A;  1G9K A;  3HDB A;  1K7Q A;  2J0T A;  2Z2D A;  2K9C A;  3KRY A;  1UTZ A;  1SMP A;  3DSL A;  1BZS A;  2USN A;  5I43 A;  1GE7 A;  4GR8 A;  2PJT A;  1PWP A;  1D8M A;  5LAB A;  2X3C A;  4FXQ A;  3OHL A;  3F19 A;  1IAA A;  2JT6 A;  1GO7 P;  3G42 A;  3V96 B;  3ZUK A;  1BQO A;  1I1I P;  3B2Z A;  3HY9 A;  5L79 A;  1ZXV A;  1FM1 A;  2MLR A;  3TS4 A;  4DV8 A;  5I12 A;  3DWB A;  5CUH A;  1BKC E;  5BOT A;  3NX7 A;  2CLT A;  1O0Q A;  2Y6D A;  3AIG A;  3E8R A;  1XUC A;  3K7N A;  3LE9 A;  1CGE A;  3F1A A;  1BQQ M;  2XS4 A;  2OXZ A;  1GXD A;  1KBC A;  4GR3 A;  4I03 A;  4AXQ A;  4J4M A;  4FXY P;  1YQY A;  1KUG A;  3L0V A;  3GBO A;  4G0D A;  4XM7 A;  3LIR A;  1ZVX A;  1SAT A;  4GUY A;  1RM8 A;  4H3X A;  4EFS A;  1BSW A;  3EDG A;  3LGP A;  1AST A;  1G4K A;  3LQ0 A;  3LQB A;  3O2X A;  4AYK A;  4XCT A;  2JSD A;  2JIH A;  1BKC A;  3LJT A;  1Y0V A;  1L6J A;  4A7B A;  4L63 A;  1EAK A;  3DPF A;  1HTD A;  3OHO A;  1XUR A;  1HFC A;  3F18 A;  3LUM A;  830C A;  1CAQ A;  4Q1L A;  3LKA A;  3LK8 A;  2CKI A;  1JH1 A;  1Q3A A;  1BKC I;  1GKC A;  5JMY A;  1CQR A;  1B3D A;  1GE5 A;  3LIL A;  3AYK A;  1UTT A;  1IAB A;  2FV5 A;  2L0R A;  1ND1 A;  1UMT A;  4PKU A;  1BUV M;  3AYU A;  1HOV A;  1I73 A;  2W12 A;  4WKE A;  1J7N A;  1DTH A;  3MA2 A;  3WV1 A;  2X3A A;  3F16 A;  2OW0 A;  2D1N A;  3Q2G A;  1JAP A;  1ZTQ A;  5D7W A;  1XFY A;  1IAC A;  1JIW P;  3VTG A;  5I4O A;  5D1T A;  3WV2 A;  1Y93 A;  3RTS A;  1D7X A;  1MMR A;  4ON1 A;  4GR0 A;  1MMQ A;  4PKQ A;  3B92 A;  1BIW A;  4PKR A;  4AIG A;  1IAD A;  4IJO A;  1JIZ A;  3EHY A;  1BUD A;  1G49 A;  3HBV P;  2WOA A;  4FVL A;  3HDA P;  1RMZ A;  4WK7 A;  3DL1 A;  1KUH A;  3LMC A;  3EDH A;  5D3C A;  2W15 A;  2W0D A;  1PWV A;  1JAO A;  4G9L A;  4JP4 A;  2DDF A;  2POJ A;  4PKS A;  1MMP A;  3HB2 P;  3UVC A;  2MLS A;  3L0T A;  2O36 A;  2OY4 A;  1XFW A;  4H84 A;  1EUB A;  1KUK A;  4JQG A;  1R1H A;  1CGL A;  2OXW A;  4AUO A;  2DDY A;  2OY2 A;  3LIK A;  3EWJ A;  4GWN A;  1ATL A;  5CZM A;  3KHI A;  1I76 A;  3G5C A;  5BPA A;  4JPA A;  1FBL A;  1HV5 A;  3HBU P;  1MMB A;  1SRP A;  2JNP A;  1CIZ A;  1GKD A;  1XFZ A;  2HU6 A;  2KRJ A;  3KEJ A;  1MNC A;  2D1O A;  4H30 A;  1R55 A;  5D2B A;  1JAN A;  1YOU A;  1XFX A;  1OS9 A;  4H2E A;  3N2U A;  4H1Q A;  4HMA A;  1JK3 A;  1Z3J A;  1PWQ A;  5BOY A;  4WKI A;  1C7K A;  3ELM A;  1SLM A;  1KUF A;  1JAQ A;  3EDZ A;  1A86 A;  1G12 A;  3K7L A;  1AKL A;  1ROS A;  2MZI A;  2E2D A;  4ILW D;  1CK7 A;  1C8T A;  1YCM A;  2J83 A;  1OS2 A;  3WV3 A;  1YP1 A;  1S4B P;  2WO8 A;  3KMC A;  2ERQ A;  1FLS A;  3TVC A;  1CGF A;  1CXV A;  2OW2 A;  4DF9 A;  4JA1 A;  2DW2 A;  4PKT A;  3ZVS A;  1GE6 A; 
#chains in the Genus database with same CATH topology
 3LJG A;  2K2G A;  3USN A;  1OZ9 A;  5L7F A;  3F15 A;  2MZH A;  2QPJ A;  2O3E A;  2YIG A;  2OZR A;  3B8Z A;  2AIG P;  1PWU A;  2OVZ A;  1BM6 A;  2I47 A;  1G05 A;  3I7I A;  1SLN A;  4HX3 A;  3HYG A;  1Y8J A;  4QKZ A;  1GO8 P;  3F17 A;  5I0L A;  3BA0 A;  1ZS0 A;  3HY7 A;  3P24 A;  1R54 A;  3DPE A;  1KAP P;  3N2V A;  3VI1 A;  1QIA A;  4DPE A;  3I7G A;  2X3B A;  4XM6 A;  2W14 A;  5B5P A;  3EDI A;  2MZE A;  1PWW A;  2ERO A;  2OW1 A;  2N8R A;  2SRT A;  4FU4 A;  1OO9 A;  4GQL A;  1R1I A;  2V4B A;  4I35 A;  966C A;  3KEK A;  3DNG A;  5I2Z A;  3TT4 A;  1OM6 A;  4IUW A;  4ZR5 A;  5I3M A;  2RJP A;  4IN9 A;  3KEC A;  1B8Y A;  1ZXC A;  3RTT A;  1XM5 A;  2AYK A;  2WO9 A;  5D1S A;  1A85 A;  2XS3 A;  4XM8 A;  3Q2H A;  1JJ9 A;  1WNI A;  4H49 A;  4H82 A;  2ERP A;  2FV9 A;  1QJI A;  3LUN A;  3SHI A;  4PKW A;  1QUA A;  1XFU A;  1IAE A;  2DW1 A;  2TCL A;  3DTI A;  2OI0 A;  1D8F A;  5CXA A;  4WF6 A;  5B5O A;  3P1V A;  1D5J A;  1HFS A;  1O0T A;  4CTH A;  1C3I A;  3TSK A;  5D1U A;  4PKV A;  4GWM A;  3ZXH A;  4A3W A;  1USN A;  1OM7 A;  1XFV A;  3CKI A;  2DW0 A;  1QJJ A;  1AF0 A;  1HY7 A;  1UMS A;  2X7M A;  3KWV C;  1KUI A;  1JKY A;  2A8H A;  1R1J A;  4R3V A;  2RJQ A;  1QIB A;  1ZP5 A;  4H76 A;  2W13 A;  1OM8 A;  1OMJ A;  456C A;  1K7I A;  3LEA A;  2E3X A;  2OXU A;  1QIC A;  4WZV A;  3LJZ A;  2Y6C A;  2YB9 A;  4DD8 A;  4GF1 A;  1H71 P;  1AYK A;  1DMT A;  2OW9 A;  2OVX A;  4L6T A;  4XBH A;  5H8X A;  3KME A;  3DTE A;  1K7G A;  1XUD A;  2JT5 A;  3O64 A;  1UEA A;  1SU3 A;  4JIJ A;  3U1R A;  3EHX A;  4L19 A;  1EB6 A;  1IAG A;  1G9K A;  3HDB A;  1K7Q A;  2J0T A;  2Z2D A;  2K9C A;  3KRY A;  1UTZ A;  1SMP A;  3DSL A;  1BZS A;  2USN A;  5I43 A;  1GE7 A;  4GR8 A;  2PJT A;  1PWP A;  1D8M A;  5LAB A;  2X3C A;  4FXQ A;  3OHL A;  3F19 A;  1IAA A;  2JT6 A;  1GO7 P;  3G42 A;  3V96 B;  3ZUK A;  1BQO A;  1I1I P;  3B2Z A;  3HY9 A;  5L79 A;  1ZXV A;  1FM1 A;  2MLR A;  3TS4 A;  4DV8 A;  5I12 A;  3DWB A;  5CUH A;  1BKC E;  5BOT A;  3NX7 A;  2CLT A;  1O0Q A;  2Y6D A;  3AIG A;  3E8R A;  1XUC A;  3K7N A;  3LE9 A;  1CGE A;  3F1A A;  1BQQ M;  2XS4 A;  2OXZ A;  1GXD A;  1KBC A;  4GR3 A;  4I03 A;  4AXQ A;  4J4M A;  4FXY P;  1YQY A;  1KUG A;  3L0V A;  3GBO A;  4G0D A;  4XM7 A;  3LIR A;  1ZVX A;  1SAT A;  4GUY A;  1RM8 A;  4H3X A;  4EFS A;  1BSW A;  3EDG A;  3LGP A;  1AST A;  1G4K A;  3LQ0 A;  3LQB A;  3O2X A;  4AYK A;  4XCT A;  2JSD A;  2JIH A;  1BKC A;  3LJT A;  1Y0V A;  1L6J A;  4A7B A;  4L63 A;  1EAK A;  3DPF A;  1HTD A;  3OHO A;  1XUR A;  1HFC A;  3F18 A;  3LUM A;  830C A;  1CAQ A;  4Q1L A;  3LKA A;  3LK8 A;  2CKI A;  1JH1 A;  1Q3A A;  1BKC I;  1GKC A;  5JMY A;  1CQR A;  1B3D A;  1GE5 A;  3LIL A;  3AYK A;  1UTT A;  1XAX A;  1IAB A;  2FV5 A;  2L0R A;  1ND1 A;  1TVI A;  1UMT A;  4PKU A;  1BUV M;  3AYU A;  2YUF A;  1HOV A;  1I73 A;  2W12 A;  4WKE A;  1J7N A;  1DTH A;  3MA2 A;  3WV1 A;  2X3A A;  3F16 A;  2OW0 A;  2D1N A;  3Q2G A;  1JAP A;  1ZTQ A;  5D7W A;  1XFY A;  1IAC A;  1JIW P;  3VTG A;  5I4O A;  5D1T A;  3WV2 A;  1Y93 A;  4L7A A;  3RTS A;  1D7X A;  1MMR A;  4ON1 A;  4GR0 A;  1MMQ A;  4PKQ A;  3B92 A;  1BIW A;  3DTK A;  4PKR A;  4AIG A;  1IAD A;  4IJO A;  1JIZ A;  3EHY A;  1BUD A;  1G49 A;  3HBV P;  2WOA A;  4FVL A;  3HDA P;  1RMZ A;  4WK7 A;  3DL1 A;  1KUH A;  3LMC A;  3EDH A;  5D3C A;  2W15 A;  2W0D A;  1PWV A;  1JAO A;  4G9L A;  4JP4 A;  2DDF A;  2POJ A;  4PKS A;  1MMP A;  3HB2 P;  3UVC A;  2MLS A;  3L0T A;  2O36 A;  2OY4 A;  1XFW A;  4H84 A;  1EUB A;  1KUK A;  4JQG A;  1R1H A;  1CGL A;  2OXW A;  4AUO A;  2DDY A;  2OY2 A;  3LIK A;  3EWJ A;  4GWN A;  1ATL A;  5CZM A;  3KHI A;  1I76 A;  3G5C A;  5BPA A;  4JPA A;  1FBL A;  1HV5 A;  3HBU P;  1MMB A;  1SRP A;  2JNP A;  1CIZ A;  1GKD A;  1XFZ A;  2HU6 A;  2KRJ A;  3KEJ A;  1MNC A;  2D1O A;  4H30 A;  1R55 A;  5D2B A;  1JAN A;  1YOU A;  1XFX A;  1OS9 A;  4H2E A;  3N2U A;  4H1Q A;  4HMA A;  1JK3 A;  1Z3J A;  1PWQ A;  5BOY A;  4WKI A;  1C7K A;  3ELM A;  1SLM A;  1KUF A;  1JAQ A;  3EDZ A;  1A86 A;  1G12 A;  3K7L A;  1AKL A;  1ROS A;  2MZI A;  2E2D A;  4ILW D;  1CK7 A;  1C8T A;  1YCM A;  2J83 A;  1OS2 A;  3WV3 A;  1YP1 A;  1S4B P;  2WO8 A;  3KMC A;  2ERQ A;  1FLS A;  3TVC A;  1CGF A;  1CXV A;  2OW2 A;  4DF9 A;  4JA1 A;  2DW2 A;  4PKT A;  3ZVS A;  1GE6 A; 
#chains in the Genus database with same CATH homology
 3LJG A;  2K2G A;  3USN A;  5L7F A;  3F15 A;  2MZH A;  2QPJ A;  2O3E A;  2YIG A;  2OZR A;  3B8Z A;  2AIG P;  1PWU A;  2OVZ A;  1BM6 A;  2I47 A;  1G05 A;  3I7I A;  1SLN A;  4HX3 A;  3HYG A;  1Y8J A;  4QKZ A;  1GO8 P;  3F17 A;  5I0L A;  3BA0 A;  1ZS0 A;  3HY7 A;  3P24 A;  1R54 A;  3DPE A;  1KAP P;  3N2V A;  3VI1 A;  1QIA A;  4DPE A;  3I7G A;  2X3B A;  4XM6 A;  2W14 A;  5B5P A;  3EDI A;  2MZE A;  1PWW A;  2ERO A;  2OW1 A;  2N8R A;  2SRT A;  4FU4 A;  1OO9 A;  4GQL A;  1R1I A;  2V4B A;  4I35 A;  966C A;  3KEK A;  3DNG A;  5I2Z A;  3TT4 A;  1OM6 A;  4IUW A;  4ZR5 A;  5I3M A;  2RJP A;  4IN9 A;  3KEC A;  1B8Y A;  1ZXC A;  3RTT A;  2AYK A;  2WO9 A;  5D1S A;  1A85 A;  2XS3 A;  4XM8 A;  3Q2H A;  1JJ9 A;  1WNI A;  4H49 A;  4H82 A;  2ERP A;  2FV9 A;  1QJI A;  3LUN A;  3SHI A;  4PKW A;  1QUA A;  1XFU A;  1IAE A;  2DW1 A;  2TCL A;  3DTI A;  2OI0 A;  1D8F A;  5CXA A;  4WF6 A;  5B5O A;  3P1V A;  1D5J A;  1HFS A;  1O0T A;  4CTH A;  1C3I A;  3TSK A;  5D1U A;  4PKV A;  4GWM A;  3ZXH A;  4A3W A;  1USN A;  1OM7 A;  1XFV A;  3CKI A;  2DW0 A;  1QJJ A;  1AF0 A;  1HY7 A;  1UMS A;  2X7M A;  3KWV C;  1KUI A;  1JKY A;  2A8H A;  1R1J A;  4R3V A;  2RJQ A;  1QIB A;  1ZP5 A;  4H76 A;  2W13 A;  1OM8 A;  1OMJ A;  456C A;  1K7I A;  3LEA A;  2E3X A;  2OXU A;  1QIC A;  4WZV A;  3LJZ A;  2Y6C A;  2YB9 A;  4DD8 A;  4GF1 A;  1H71 P;  1AYK A;  1DMT A;  2OW9 A;  2OVX A;  4L6T A;  4XBH A;  5H8X A;  3KME A;  3DTE A;  1K7G A;  1XUD A;  2JT5 A;  3O64 A;  1UEA A;  1SU3 A;  4JIJ A;  3U1R A;  3EHX A;  4L19 A;  1EB6 A;  1IAG A;  1G9K A;  3HDB A;  1K7Q A;  2J0T A;  2Z2D A;  2K9C A;  3KRY A;  1UTZ A;  1SMP A;  3DSL A;  1BZS A;  2USN A;  5I43 A;  1GE7 A;  4GR8 A;  2PJT A;  1PWP A;  1D8M A;  5LAB A;  2X3C A;  4FXQ A;  3OHL A;  3F19 A;  1IAA A;  2JT6 A;  1GO7 P;  3G42 A;  3V96 B;  3ZUK A;  1BQO A;  1I1I P;  3B2Z A;  3HY9 A;  5L79 A;  1ZXV A;  1FM1 A;  2MLR A;  3TS4 A;  4DV8 A;  5I12 A;  3DWB A;  5CUH A;  1BKC E;  5BOT A;  3NX7 A;  2CLT A;  1O0Q A;  2Y6D A;  3AIG A;  3E8R A;  1XUC A;  3K7N A;  3LE9 A;  1CGE A;  3F1A A;  1BQQ M;  2XS4 A;  2OXZ A;  1GXD A;  1KBC A;  4GR3 A;  4I03 A;  4AXQ A;  4J4M A;  4FXY P;  1YQY A;  1KUG A;  3L0V A;  3GBO A;  4G0D A;  4XM7 A;  3LIR A;  1ZVX A;  1SAT A;  4GUY A;  1RM8 A;  4H3X A;  4EFS A;  1BSW A;  3EDG A;  3LGP A;  1AST A;  1G4K A;  3LQ0 A;  3LQB A;  3O2X A;  4AYK A;  4XCT A;  2JSD A;  2JIH A;  1BKC A;  3LJT A;  1Y0V A;  1L6J A;  4A7B A;  4L63 A;  1EAK A;  3DPF A;  1HTD A;  3OHO A;  1XUR A;  1HFC A;  3F18 A;  3LUM A;  830C A;  1CAQ A;  4Q1L A;  3LKA A;  3LK8 A;  2CKI A;  1JH1 A;  1Q3A A;  1BKC I;  1GKC A;  5JMY A;  1CQR A;  1B3D A;  1GE5 A;  3LIL A;  3AYK A;  1UTT A;  1IAB A;  2FV5 A;  2L0R A;  1ND1 A;  1UMT A;  4PKU A;  1BUV M;  3AYU A;  2YUF A;  1HOV A;  1I73 A;  2W12 A;  4WKE A;  1J7N A;  1DTH A;  3MA2 A;  3WV1 A;  2X3A A;  3F16 A;  2OW0 A;  2D1N A;  3Q2G A;  1JAP A;  1ZTQ A;  5D7W A;  1XFY A;  1IAC A;  1JIW P;  3VTG A;  5I4O A;  5D1T A;  3WV2 A;  1Y93 A;  4L7A A;  3RTS A;  1D7X A;  1MMR A;  4ON1 A;  4GR0 A;  1MMQ A;  4PKQ A;  3B92 A;  1BIW A;  3DTK A;  4PKR A;  4AIG A;  1IAD A;  4IJO A;  1JIZ A;  3EHY A;  1BUD A;  1G49 A;  3HBV P;  2WOA A;  4FVL A;  3HDA P;  1RMZ A;  4WK7 A;  3DL1 A;  1KUH A;  3LMC A;  3EDH A;  5D3C A;  2W15 A;  2W0D A;  1PWV A;  1JAO A;  4G9L A;  4JP4 A;  2DDF A;  2POJ A;  4PKS A;  1MMP A;  3HB2 P;  3UVC A;  2MLS A;  3L0T A;  2O36 A;  2OY4 A;  1XFW A;  4H84 A;  1EUB A;  1KUK A;  4JQG A;  1R1H A;  1CGL A;  2OXW A;  4AUO A;  2DDY A;  2OY2 A;  3LIK A;  3EWJ A;  4GWN A;  1ATL A;  5CZM A;  3KHI A;  1I76 A;  3G5C A;  5BPA A;  4JPA A;  1FBL A;  1HV5 A;  3HBU P;  1MMB A;  1SRP A;  2JNP A;  1CIZ A;  1GKD A;  1XFZ A;  2HU6 A;  2KRJ A;  3KEJ A;  1MNC A;  2D1O A;  4H30 A;  1R55 A;  5D2B A;  1JAN A;  1YOU A;  1XFX A;  1OS9 A;  4H2E A;  3N2U A;  4H1Q A;  4HMA A;  1JK3 A;  1Z3J A;  1PWQ A;  5BOY A;  4WKI A;  1C7K A;  3ELM A;  1SLM A;  1KUF A;  1JAQ A;  3EDZ A;  1A86 A;  1G12 A;  3K7L A;  1AKL A;  1ROS A;  2MZI A;  2E2D A;  4ILW D;  1CK7 A;  1C8T A;  1YCM A;  2J83 A;  1OS2 A;  3WV3 A;  1YP1 A;  1S4B P;  2WO8 A;  3KMC A;  2ERQ A;  1FLS A;  3TVC A;  1CGF A;  1CXV A;  2OW2 A;  4DF9 A;  4JA1 A;  2DW2 A;  4PKT A;  3ZVS A;  1GE6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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