3Q2GA

Adamts1 in complex with a novel n-hydroxyformamide inhibitors
Total Genus 92
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
92
sequence length
296
structure length
282
Chain Sequence
SHRYVETMLVADQSMAEFHGSGLKHYLLTLFSVAARLYKHPSIRNSVSLVVVKILVIHDEQKGPEVTSNAALTLRNFCNWQKQHNPPSDRDAEHYDTAILFTRQDLCGSQTCDTLGMADVGTVCDPSRSCSVIEDDGLQAAFTTAHELGHVFNMPHDDAKQCASLNSHMMASMLSNLDHSQPWSPCSAYMITSFLDNGHGECLMDKPQNPIQLPGDLPGTSYDANRQCQFTFGEDSKHCPTCSTLWCTGLVCQTKHFPWADGTSCGEGKWCINGKCVNKLVP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The design and synthesis of novel N-hydroxyformamide inhibitors of ADAM-TS4 for the treatment of osteoarthritis
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords A disintegrin and metalloproteinase with thrombospondin moti
total genus 92
structure length 282
sequence length 296
chains with identical sequence B
ec nomenclature ec 3.4.24.-:
pdb deposition date 2010-12-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01421 Reprolysin Reprolysin (M12B) family zinc metalloprotease
A PF17771 ADAM_CR_2 ADAM cysteine-rich domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3q2gA01
1JJ9A 1SATA 3F1AA 1IAAA 1BQQM 5BOYA 1PWQA 4XM6A 1S4BP 1UTTA 2K9CA 3F17A 3EHXA 1ROSA 3WV1A 3BA0A 2XS3A 3SHIA 3G42A 5D1TA 1L6JA 3KRYA 4A3WA 3KEJA 3LGPA 4GWMA 4H76A 1IADA 2W0DA 4AIGA 1O0TA 2A8HA 2SRTA 1YQYA 3G5CA 1ZXCA 2MZHA 2FV5A 4L63A 4DF9A 2I47A 2ERQA 4I35A 1K7IA 2JIHA 1KBCA 3HY9A 4PKWA 2XS4A 4GWNA 4HMAA 456CA 1BKCA 2WOAA 3LUNA 4AUOA 5I2ZA 2OW1A 1KAPP 1QUAA 2W15A 1USNA 4GUYA 4FVLA 1AKLA 4WF6A 2YIGA 5I12A 5L79A 3KEKA 4FXQA 3LILA 3L0TA 1QJJA 3LJZA 3DSLA 3ZXHA 1FLSA 5D3CA 3EDHA 1HFCA 2MZIA 4G0DA 3L0VA 1OO9A 1PWPA 3VI1A 4WZVA 3TSKA 4XCTA 5JMYA 830CA 1ND1A 2Y6CA 1JK3A 3KWVC 1OMJA 2OZRA 2QPJA 2O3EA 4JPAA 4H3XA 2E3XA 1G12A 3F18A 1R1JA 2W13A 1BKCE 2PJTA 3OHOA 2JT5A 2FV9A 1FBLA 1ATLA 3HDBA 1ZP5A 4GR0A 2OI0A 2MLSA 4J4MA 2OW0A 1H71P 4HX3A 3DL1A 1JKYA 1IAEA 1R54A 4WK7A 1K7GA 1UMTA 1BZSA 4JQGA 5CZMA 3O64A 2J83A 4JIJA 1ZVXA 3F15A 2K2GA 2Y6DA 3WV2A 1XFUA 2O36A 1JAPA 3LUMA 5I0LA 1SMPA 4L6TA 1OM7A 4IN9A 4XBHA 1R1IA 2X3CA 3RTTA 2RJQA 3DNGA 5BOTA 3Q2GA 4R3VA 1CXVA 3Q2HA 5I3MA 1I73A 4H2EA 4JA1A 5BPAA 4WKIA 1GO8P 2OW9A 1MMQA 4FU4A 4ON1A 3F19A 2AYKA 4G9LA 1OM8A 3AIGA 1I76A 3I7IA 4PKSA 1GO7P 1Z3JA 2Z2DA 1CQRA 5CUHA 1GE7A 1HTDA 1GKDA 3HY7A 3AYUA 2OVXA 4JP4A 3B2ZA 1UMSA 3LMCA 3HB2P 4PKQA 1G9KA 1D7XA 1AF0A 1BUVM 1JAQA 4DPEA 3F16A 1GKCA 4GR3A 4QKZA 2L0RA 2X3BA 3KHIA 3LIRA 3NX7A 3RTSA 3HDAP 2OXUA 1HOVA 1A85A 1R55A 2J0TA 3GBOA 1K7QA 1D5JA 1BQOA 3P1VA 4GF1A 2AIGP 2CLTA 1IACA 4GR8A 2POJA 5H8XA 2ERPA 3TVCA 1YOUA 1G05A 4H49A 2D1OA 3WV3A 3HYGA 1BUDA 1PWWA 1PWUA 1JANA 4PKVA 1Y0VA 2TCLA 5D7WA 3HBUP 4AYKA 3O2XA 1OS2A 2V4BA 1KUIA 1XFVA 1ZXVA 1XFZA 1G4KA 5B5OA 3EWJA 2OXZA 3DPFA 4WKEA 4PKRA 1KUGA 3EDIA 2OW2A 4PKTA 1A86A 3USNA 2EROA 2HU6A 2OY4A 1OM6A 1D8MA 4H84A 1AYKA 3EDZA 2OY2A 1BSWA 1I1IP 1GE5A 1EAKA 1XFYA 4GQLA 2JSDA 1HY7A 1JAOA 1MMRA 1MNCA 3ZUKA 2WO8A 2JNPA 1YP1A 1ASTA 1KUHA 3DWBA 3VTGA 1SLNA 5I4OA 3OHLA 5D1SA 4XM7A 1EUBA 3LJGA 3EHYA 1O0QA 4H82A 1BM6A 1FM1A 1CGFA 1R1HA 1Y8JA 3K7NA 1QICA 2DW1A 5L7FA 3U1RA 1Q3AA 1WNIA 4AXQA 3TT4A 3LJTA 2E2DA 1YCMA 1JIWP 4CTHA 3DPEA 1IABA 1XFWA 1CGEA 5D1UA 3ZVSA 2DW0A 1QIBA 4I03A 3LQ0A 3V96B 1MMPA 3EDGA 3LIKA 4ILWD 1CIZA 3KMCA 3CKIA 1BIWA 1PWVA 2MZEA 2DDYA 2JT6A 1HFSA 1B8YA 2WO9A 3KECA 3LK8A 2X7MA 3E8RA 1HV5A 5LABA 2YB9A 4XM8A 4FXYP 3I7GA 1XFXA 1SLMA 2RJPA 1RM8A 1ZTQA 1GE6A 5B5PA 2DDFA 1DMTA 2CKIA 1GXDA 2W14A 1JIZA 1QIAA 4IJOA 4PKUA 3UVCA 3ELMA 1XUDA 2OXWA 1C8TA 4H1QA 1CK7A 1QJIA 2N8RA 3HBVP 4ZR5A 2KRJA 1CAQA 2W12A 1RMZA 2D1NA 1G49A 1KUKA 3LE9A 4H30A 3N2VA 3B8ZA 1UEAA 1SU3A 5D2BA 3LEAA 1XUCA 3K7LA 1C7KA 1J7NA 4A7BA 3AYKA 1IAGA 1C3IA 4DD8A 1KUFA 4L19A 4EFSA 3MA2A 1JH1A 1XURA 2MLRA 1OS9A 1Y93A 1ZS0A 4DV8A 5CXAA 5I43A 3P24A 3LQBA 1UTZA 2DW2A 3KMEA 1DTHA 1EB6A 1BKCI 1B3DA 4Q1LA 3LKAA 3B92A 1CGLA 1MMBA 3TS4A 1SRPA 3N2UA 2OVZA 966CA 2X3AA 4IUWA 1D8FA 2USNA
chains in the Genus database with same CATH superfamily
1JJ9A 1SATA 3F1AA 1IAAA 1BQQM 5BOYA 1PWQA 4XM6A 1S4BP 1UTTA 2K9CA 3F17A 3EHXA 1ROSA 3WV1A 3BA0A 2XS3A 3SHIA 3G42A 5D1TA 1L6JA 3KRYA 4A3WA 3KEJA 3LGPA 4GWMA 4H76A 1IADA 2W0DA 4AIGA 1O0TA 2A8HA 2SRTA 1YQYA 3G5CA 1ZXCA 2MZHA 2FV5A 4L63A 4DF9A 2I47A 2ERQA 4I35A 1K7IA 2JIHA 1KBCA 3HY9A 4PKWA 2XS4A 4GWNA 4HMAA 456CA 1BKCA 2WOAA 3LUNA 4AUOA 5I2ZA 2OW1A 1KAPP 1QUAA 2W15A 1USNA 4GUYA 4FVLA 1AKLA 4WF6A 2YIGA 5I12A 5L79A 3KEKA 4FXQA 3LILA 3L0TA 1QJJA 3LJZA 3DSLA 3ZXHA 1FLSA 5D3CA 3EDHA 1HFCA 2MZIA 4G0DA 3L0VA 1OO9A 1PWPA 3VI1A 4WZVA 3TSKA 4XCTA 5JMYA 830CA 1ND1A 2Y6CA 1JK3A 3KWVC 1OMJA 2OZRA 2QPJA 2O3EA 4JPAA 4H3XA 2E3XA 1G12A 3F18A 1R1JA 2W13A 1BKCE 2PJTA 3OHOA 2JT5A 2FV9A 1FBLA 1ATLA 3HDBA 1ZP5A 4GR0A 2OI0A 2MLSA 4J4MA 2OW0A 1H71P 4HX3A 3DL1A 1JKYA 1IAEA 1R54A 4WK7A 1K7GA 1UMTA 1BZSA 4JQGA 5CZMA 3O64A 2J83A 4JIJA 1ZVXA 3F15A 2K2GA 2Y6DA 3WV2A 1XFUA 2O36A 1JAPA 3LUMA 5I0LA 1SMPA 1OZ9A 4L6TA 1OM7A 4IN9A 4XBHA 1R1IA 2X3CA 3RTTA 2RJQA 3DNGA 5BOTA 3Q2GA 4R3VA 1CXVA 3Q2HA 5I3MA 1I73A 4H2EA 4JA1A 5BPAA 4WKIA 1GO8P 2OW9A 1MMQA 4FU4A 4ON1A 1XAXA 3F19A 2AYKA 4G9LA 1OM8A 3AIGA 1I76A 3I7IA 4PKSA 1GO7P 1Z3JA 2Z2DA 1CQRA 5CUHA 1GE7A 1HTDA 1GKDA 3HY7A 3AYUA 2OVXA 4JP4A 3B2ZA 1UMSA 3LMCA 3HB2P 4PKQA 1G9KA 1D7XA 1AF0A 1BUVM 1JAQA 4DPEA 3F16A 1GKCA 4GR3A 4QKZA 2L0RA 2X3BA 3KHIA 3LIRA 3NX7A 3RTSA 3HDAP 2OXUA 1HOVA 3DTKA 1A85A 1R55A 2J0TA 3GBOA 1K7QA 1D5JA 1XM5A 1BQOA 3P1VA 4GF1A 2AIGP 2CLTA 1IACA 4GR8A 2POJA 5H8XA 2ERPA 3TVCA 1YOUA 1G05A 4H49A 2D1OA 3WV3A 3HYGA 1BUDA 1PWWA 3DTIA 1PWUA 1JANA 4PKVA 1Y0VA 2TCLA 5D7WA 3HBUP 4AYKA 3O2XA 1OS2A 2V4BA 1KUIA 1XFVA 1ZXVA 1XFZA 1G4KA 5B5OA 3EWJA 2OXZA 3DPFA 4WKEA 4PKRA 1KUGA 3EDIA 2OW2A 4PKTA 1A86A 3USNA 2EROA 2HU6A 2OY4A 1OM6A 1D8MA 4H84A 1AYKA 3EDZA 2OY2A 1BSWA 1I1IP 1GE5A 1EAKA 1XFYA 4GQLA 2JSDA 1HY7A 1JAOA 1MMRA 1MNCA 3ZUKA 2WO8A 2JNPA 1YP1A 1ASTA 1KUHA 3DWBA 3VTGA 1SLNA 5I4OA 3OHLA 5D1SA 4XM7A 1EUBA 3LJGA 3EHYA 1O0QA 4H82A 1BM6A 1FM1A 1CGFA 1R1HA 1Y8JA 3K7NA 1QICA 2DW1A 5L7FA 3U1RA 1Q3AA 1WNIA 4AXQA 3TT4A 3LJTA 2E2DA 1YCMA 3DTEA 1JIWP 4CTHA 3DPEA 1IABA 1XFWA 1CGEA 5D1UA 3ZVSA 2DW0A 1QIBA 4I03A 3LQ0A 3V96B 1MMPA 3EDGA 3LIKA 4ILWD 1CIZA 3KMCA 3CKIA 1BIWA 1PWVA 2MZEA 2DDYA 2JT6A 1HFSA 1B8YA 2WO9A 3KECA 3LK8A 2X7MA 1TVIA 3E8RA 1HV5A 5LABA 2YB9A 4XM8A 4FXYP 3I7GA 1XFXA 1SLMA 2RJPA 1RM8A 1ZTQA 1GE6A 5B5PA 2DDFA 1DMTA 2CKIA 1GXDA 2W14A 1JIZA 1QIAA 4IJOA 4PKUA 3UVCA 3ELMA 1XUDA 2OXWA 1C8TA 4H1QA 1CK7A 1QJIA 2N8RA 3HBVP 4L7AA 4ZR5A 2KRJA 1CAQA 2W12A 1RMZA 2D1NA 1G49A 1KUKA 3LE9A 4H30A 3N2VA 3B8ZA 1UEAA 1SU3A 5D2BA 3LEAA 1XUCA 3K7LA 1C7KA 1J7NA 4A7BA 3AYKA 1IAGA 1C3IA 4DD8A 1KUFA 4L19A 4EFSA 3MA2A 1JH1A 1XURA 2MLRA 1OS9A 1Y93A 1ZS0A 4DV8A 5CXAA 5I43A 3P24A 3LQBA 1UTZA 2DW2A 3KMEA 2YUFA 1DTHA 1EB6A 1BKCI 1B3DA 4Q1LA 3LKAA 3B92A 1CGLA 1MMBA 3TS4A 1SRPA 3N2UA 2OVZA 966CA 2X3AA 4IUWA 1D8FA 2USNA
chains in the Genus database with same CATH topology
1JJ9A 1SATA 3F1AA 1IAAA 1BQQM 5BOYA 1PWQA 4XM6A 1S4BP 1UTTA 2K9CA 3F17A 3EHXA 1ROSA 3WV1A 3BA0A 2XS3A 3SHIA 3G42A 5D1TA 1L6JA 3KRYA 4A3WA 3KEJA 3LGPA 4GWMA 4H76A 1IADA 2W0DA 4AIGA 1O0TA 2A8HA 2SRTA 1YQYA 3G5CA 1ZXCA 2MZHA 2FV5A 4L63A 4DF9A 2I47A 2ERQA 4I35A 1K7IA 2JIHA 1KBCA 3HY9A 4PKWA 2XS4A 4GWNA 4HMAA 456CA 1BKCA 2WOAA 3LUNA 4AUOA 5I2ZA 2OW1A 1KAPP 1QUAA 2W15A 1USNA 4GUYA 4FVLA 1AKLA 4WF6A 2YIGA 5I12A 5L79A 3KEKA 4FXQA 3LILA 3L0TA 1QJJA 3LJZA 3DSLA 3ZXHA 1FLSA 5D3CA 3EDHA 1HFCA 2MZIA 4G0DA 3L0VA 1OO9A 1PWPA 3VI1A 4WZVA 3TSKA 4XCTA 5JMYA 830CA 1ND1A 2Y6CA 1JK3A 3KWVC 1OMJA 2OZRA 2QPJA 2O3EA 4JPAA 4H3XA 2E3XA 1G12A 3F18A 1R1JA 2W13A 1BKCE 2PJTA 3OHOA 2JT5A 2FV9A 1FBLA 1ATLA 3HDBA 1ZP5A 4GR0A 2OI0A 2MLSA 4J4MA 2OW0A 1H71P 4HX3A 3DL1A 1JKYA 1IAEA 1R54A 4WK7A 1K7GA 1UMTA 1BZSA 4JQGA 5CZMA 3O64A 2J83A 4JIJA 1ZVXA 3F15A 2K2GA 2Y6DA 3WV2A 1XFUA 2O36A 1JAPA 3LUMA 5I0LA 1SMPA 4L6TA 1OM7A 4IN9A 4XBHA 1R1IA 2X3CA 3RTTA 2RJQA 3DNGA 5BOTA 3Q2GA 4R3VA 1CXVA 3Q2HA 5I3MA 1I73A 4H2EA 4JA1A 5BPAA 4WKIA 1GO8P 2OW9A 1MMQA 4FU4A 4ON1A 3F19A 2AYKA 4G9LA 1OM8A 3AIGA 1I76A 3I7IA 4PKSA 1GO7P 1Z3JA 2Z2DA 1CQRA 5CUHA 1GE7A 1HTDA 1GKDA 3HY7A 3AYUA 2OVXA 4JP4A 3B2ZA 1UMSA 3LMCA 3HB2P 4PKQA 1G9KA 1D7XA 1AF0A 1BUVM 1JAQA 4DPEA 3F16A 1GKCA 4GR3A 4QKZA 2L0RA 2X3BA 3KHIA 3LIRA 3NX7A 3RTSA 3HDAP 2OXUA 1HOVA 3DTKA 1A85A 1R55A 2J0TA 3GBOA 1K7QA 1D5JA 1BQOA 3P1VA 4GF1A 2AIGP 2CLTA 1IACA 4GR8A 2POJA 5H8XA 2ERPA 3TVCA 1YOUA 1G05A 4H49A 2D1OA 3WV3A 3HYGA 1BUDA 1PWWA 3DTIA 1PWUA 1JANA 4PKVA 1Y0VA 2TCLA 5D7WA 3HBUP 4AYKA 3O2XA 1OS2A 2V4BA 1KUIA 1XFVA 1ZXVA 1XFZA 1G4KA 5B5OA 3EWJA 2OXZA 3DPFA 4WKEA 4PKRA 1KUGA 3EDIA 2OW2A 4PKTA 1A86A 3USNA 2EROA 2HU6A 2OY4A 1OM6A 1D8MA 4H84A 1AYKA 3EDZA 2OY2A 1BSWA 1I1IP 1GE5A 1EAKA 1XFYA 4GQLA 2JSDA 1HY7A 1JAOA 1MMRA 1MNCA 3ZUKA 2WO8A 2JNPA 1YP1A 1ASTA 1KUHA 3DWBA 3VTGA 1SLNA 5I4OA 3OHLA 5D1SA 4XM7A 1EUBA 3LJGA 3EHYA 1O0QA 4H82A 1BM6A 1FM1A 1CGFA 1R1HA 1Y8JA 3K7NA 1QICA 2DW1A 5L7FA 3U1RA 1Q3AA 1WNIA 4AXQA 3TT4A 3LJTA 2E2DA 1YCMA 3DTEA 1JIWP 4CTHA 3DPEA 1IABA 1XFWA 1CGEA 5D1UA 3ZVSA 2DW0A 1QIBA 4I03A 3LQ0A 3V96B 1MMPA 3EDGA 3LIKA 4ILWD 1CIZA 3KMCA 3CKIA 1BIWA 1PWVA 2MZEA 2DDYA 2JT6A 1HFSA 1B8YA 2WO9A 3KECA 3LK8A 2X7MA 3E8RA 1HV5A 5LABA 2YB9A 4XM8A 4FXYP 3I7GA 1XFXA 1SLMA 2RJPA 1RM8A 1ZTQA 1GE6A 5B5PA 2DDFA 1DMTA 2CKIA 1GXDA 2W14A 1JIZA 1QIAA 4IJOA 4PKUA 3UVCA 3ELMA 1XUDA 2OXWA 1C8TA 4H1QA 1CK7A 1QJIA 2N8RA 3HBVP 4L7AA 4ZR5A 2KRJA 1CAQA 2W12A 1RMZA 2D1NA 1G49A 1KUKA 3LE9A 4H30A 3N2VA 3B8ZA 1UEAA 1SU3A 5D2BA 3LEAA 1XUCA 3K7LA 1C7KA 1J7NA 4A7BA 3AYKA 1IAGA 1C3IA 4DD8A 1KUFA 4L19A 4EFSA 3MA2A 1JH1A 1XURA 2MLRA 1OS9A 1Y93A 1ZS0A 4DV8A 5CXAA 5I43A 3P24A 3LQBA 1UTZA 2DW2A 3KMEA 2YUFA 1DTHA 1EB6A 1BKCI 1B3DA 4Q1LA 3LKAA 3B92A 1CGLA 1MMBA 3TS4A 1SRPA 3N2UA 2OVZA 966CA 2X3AA 4IUWA 1D8FA 2USNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JJ9 A;  1SAT A;  3F1A A;  1IAA A;  1BQQ M;  5BOY A;  1PWQ A;  4XM6 A;  1S4B P;  1UTT A;  2K9C A;  3F17 A;  3EHX A;  1ROS A;  3WV1 A;  3BA0 A;  2XS3 A;  3SHI A;  3G42 A;  5D1T A;  1L6J A;  3KRY A;  4A3W A;  3KEJ A;  3LGP A;  4GWM A;  4H76 A;  1IAD A;  2W0D A;  4AIG A;  1O0T A;  2A8H A;  2SRT A;  1YQY A;  3G5C A;  1ZXC A;  2MZH A;  2FV5 A;  4L63 A;  4DF9 A;  2I47 A;  2ERQ A;  4I35 A;  1K7I A;  2JIH A;  1KBC A;  3HY9 A;  4PKW A;  2XS4 A;  4GWN A;  4HMA A;  456C A;  1BKC A;  2WOA A;  3LUN A;  4AUO A;  5I2Z A;  2OW1 A;  1KAP P;  1QUA A;  2W15 A;  1USN A;  4GUY A;  4FVL A;  1AKL A;  4WF6 A;  2YIG A;  5I12 A;  5L79 A;  3KEK A;  4FXQ A;  3LIL A;  3L0T A;  1QJJ A;  3LJZ A;  3DSL A;  3ZXH A;  1FLS A;  5D3C A;  3EDH A;  1HFC A;  2MZI A;  4G0D A;  3L0V A;  1OO9 A;  1PWP A;  3VI1 A;  4WZV A;  3TSK A;  4XCT A;  5JMY A;  830C A;  1ND1 A;  2Y6C A;  1JK3 A;  3KWV C;  1OMJ A;  2OZR A;  2QPJ A;  2O3E A;  4JPA A;  4H3X A;  2E3X A;  1G12 A;  3F18 A;  1R1J A;  2W13 A;  1BKC E;  2PJT A;  3OHO A;  2JT5 A;  2FV9 A;  1FBL A;  1ATL A;  3HDB A;  1ZP5 A;  4GR0 A;  2OI0 A;  2MLS A;  4J4M A;  2OW0 A;  1H71 P;  4HX3 A;  3DL1 A;  1JKY A;  1IAE A;  1R54 A;  4WK7 A;  1K7G A;  1UMT A;  1BZS A;  4JQG A;  5CZM A;  3O64 A;  2J83 A;  4JIJ A;  1ZVX A;  3F15 A;  2K2G A;  2Y6D A;  3WV2 A;  1XFU A;  2O36 A;  1JAP A;  3LUM A;  5I0L A;  1SMP A;  4L6T A;  1OM7 A;  4IN9 A;  4XBH A;  1R1I A;  2X3C A;  3RTT A;  2RJQ A;  3DNG A;  5BOT A;  3Q2G A;  4R3V A;  1CXV A;  3Q2H A;  5I3M A;  1I73 A;  4H2E A;  4JA1 A;  5BPA A;  4WKI A;  1GO8 P;  2OW9 A;  1MMQ A;  4FU4 A;  4ON1 A;  3F19 A;  2AYK A;  4G9L A;  1OM8 A;  3AIG A;  1I76 A;  3I7I A;  4PKS A;  1GO7 P;  1Z3J A;  2Z2D A;  1CQR A;  5CUH A;  1GE7 A;  1HTD A;  1GKD A;  3HY7 A;  3AYU A;  2OVX A;  4JP4 A;  3B2Z A;  1UMS A;  3LMC A;  3HB2 P;  4PKQ A;  1G9K A;  1D7X A;  1AF0 A;  1BUV M;  1JAQ A;  4DPE A;  3F16 A;  1GKC A;  4GR3 A;  4QKZ A;  2L0R A;  2X3B A;  3KHI A;  3LIR A;  3NX7 A;  3RTS A;  3HDA P;  2OXU A;  1HOV A;  1A85 A;  1R55 A;  2J0T A;  3GBO A;  1K7Q A;  1D5J A;  1BQO A;  3P1V A;  4GF1 A;  2AIG P;  2CLT A;  1IAC A;  4GR8 A;  2POJ A;  5H8X A;  2ERP A;  3TVC A;  1YOU A;  1G05 A;  4H49 A;  2D1O A;  3WV3 A;  3HYG A;  1BUD A;  1PWW A;  1PWU A;  1JAN A;  4PKV A;  1Y0V A;  2TCL A;  5D7W A;  3HBU P;  4AYK A;  3O2X A;  1OS2 A;  2V4B A;  1KUI A;  1XFV A;  1ZXV A;  1XFZ A;  1G4K A;  5B5O A;  3EWJ A;  2OXZ A;  3DPF A;  4WKE A;  4PKR A;  1KUG A;  3EDI A;  2OW2 A;  4PKT A;  1A86 A;  3USN A;  2ERO A;  2HU6 A;  2OY4 A;  1OM6 A;  1D8M A;  4H84 A;  1AYK A;  3EDZ A;  2OY2 A;  1BSW A;  1I1I P;  1GE5 A;  1EAK A;  1XFY A;  4GQL A;  2JSD A;  1HY7 A;  1JAO A;  1MMR A;  1MNC A;  3ZUK A;  2WO8 A;  2JNP A;  1YP1 A;  1AST A;  1KUH A;  3DWB A;  3VTG A;  1SLN A;  5I4O A;  3OHL A;  5D1S A;  4XM7 A;  1EUB A;  3LJG A;  3EHY A;  1O0Q A;  4H82 A;  1BM6 A;  1FM1 A;  1CGF A;  1R1H A;  1Y8J A;  3K7N A;  1QIC A;  2DW1 A;  5L7F A;  3U1R A;  1Q3A A;  1WNI A;  4AXQ A;  3TT4 A;  3LJT A;  2E2D A;  1YCM A;  1JIW P;  4CTH A;  3DPE A;  1IAB A;  1XFW A;  1CGE A;  5D1U A;  3ZVS A;  2DW0 A;  1QIB A;  4I03 A;  3LQ0 A;  3V96 B;  1MMP A;  3EDG A;  3LIK A;  4ILW D;  1CIZ A;  3KMC A;  3CKI A;  1BIW A;  1PWV A;  2MZE A;  2DDY A;  2JT6 A;  1HFS A;  1B8Y A;  2WO9 A;  3KEC A;  3LK8 A;  2X7M A;  3E8R A;  1HV5 A;  5LAB A;  2YB9 A;  4XM8 A;  4FXY P;  3I7G A;  1XFX A;  1SLM A;  2RJP A;  1RM8 A;  1ZTQ A;  1GE6 A;  5B5P A;  2DDF A;  1DMT A;  2CKI A;  1GXD A;  2W14 A;  1JIZ A;  1QIA A;  4IJO A;  4PKU A;  3UVC A;  3ELM A;  1XUD A;  2OXW A;  1C8T A;  4H1Q A;  1CK7 A;  1QJI A;  2N8R A;  3HBV P;  4ZR5 A;  2KRJ A;  1CAQ A;  2W12 A;  1RMZ A;  2D1N A;  1G49 A;  1KUK A;  3LE9 A;  4H30 A;  3N2V A;  3B8Z A;  1UEA A;  1SU3 A;  5D2B A;  3LEA A;  1XUC A;  3K7L A;  1C7K A;  1J7N A;  4A7B A;  3AYK A;  1IAG A;  1C3I A;  4DD8 A;  1KUF A;  4L19 A;  4EFS A;  3MA2 A;  1JH1 A;  1XUR A;  2MLR A;  1OS9 A;  1Y93 A;  1ZS0 A;  4DV8 A;  5CXA A;  5I43 A;  3P24 A;  3LQB A;  1UTZ A;  2DW2 A;  3KME A;  1DTH A;  1EB6 A;  1BKC I;  1B3D A;  4Q1L A;  3LKA A;  3B92 A;  1CGL A;  1MMB A;  3TS4 A;  1SRP A;  3N2U A;  2OVZ A;  966C A;  2X3A A;  4IUW A;  1D8F A;  2USN A; 
#chains in the Genus database with same CATH topology
 1JJ9 A;  1SAT A;  3F1A A;  1IAA A;  1BQQ M;  5BOY A;  1PWQ A;  4XM6 A;  1S4B P;  1UTT A;  2K9C A;  3F17 A;  3EHX A;  1ROS A;  3WV1 A;  3BA0 A;  2XS3 A;  3SHI A;  3G42 A;  5D1T A;  1L6J A;  3KRY A;  4A3W A;  3KEJ A;  3LGP A;  4GWM A;  4H76 A;  1IAD A;  2W0D A;  4AIG A;  1O0T A;  2A8H A;  2SRT A;  1YQY A;  3G5C A;  1ZXC A;  2MZH A;  2FV5 A;  4L63 A;  4DF9 A;  2I47 A;  2ERQ A;  4I35 A;  1K7I A;  2JIH A;  1KBC A;  3HY9 A;  4PKW A;  2XS4 A;  4GWN A;  4HMA A;  456C A;  1BKC A;  2WOA A;  3LUN A;  4AUO A;  5I2Z A;  2OW1 A;  1KAP P;  1QUA A;  2W15 A;  1USN A;  4GUY A;  4FVL A;  1AKL A;  4WF6 A;  2YIG A;  5I12 A;  5L79 A;  3KEK A;  4FXQ A;  3LIL A;  3L0T A;  1QJJ A;  3LJZ A;  3DSL A;  3ZXH A;  1FLS A;  5D3C A;  3EDH A;  1HFC A;  2MZI A;  4G0D A;  3L0V A;  1OO9 A;  1PWP A;  3VI1 A;  4WZV A;  3TSK A;  4XCT A;  5JMY A;  830C A;  1ND1 A;  2Y6C A;  1JK3 A;  3KWV C;  1OMJ A;  2OZR A;  2QPJ A;  2O3E A;  4JPA A;  4H3X A;  2E3X A;  1G12 A;  3F18 A;  1R1J A;  2W13 A;  1BKC E;  2PJT A;  3OHO A;  2JT5 A;  2FV9 A;  1FBL A;  1ATL A;  3HDB A;  1ZP5 A;  4GR0 A;  2OI0 A;  2MLS A;  4J4M A;  2OW0 A;  1H71 P;  4HX3 A;  3DL1 A;  1JKY A;  1IAE A;  1R54 A;  4WK7 A;  1K7G A;  1UMT A;  1BZS A;  4JQG A;  5CZM A;  3O64 A;  2J83 A;  4JIJ A;  1ZVX A;  3F15 A;  2K2G A;  2Y6D A;  3WV2 A;  1XFU A;  2O36 A;  1JAP A;  3LUM A;  5I0L A;  1SMP A;  1OZ9 A;  4L6T A;  1OM7 A;  4IN9 A;  4XBH A;  1R1I A;  2X3C A;  3RTT A;  2RJQ A;  3DNG A;  5BOT A;  3Q2G A;  4R3V A;  1CXV A;  3Q2H A;  5I3M A;  1I73 A;  4H2E A;  4JA1 A;  5BPA A;  4WKI A;  1GO8 P;  2OW9 A;  1MMQ A;  4FU4 A;  4ON1 A;  1XAX A;  3F19 A;  2AYK A;  4G9L A;  1OM8 A;  3AIG A;  1I76 A;  3I7I A;  4PKS A;  1GO7 P;  1Z3J A;  2Z2D A;  1CQR A;  5CUH A;  1GE7 A;  1HTD A;  1GKD A;  3HY7 A;  3AYU A;  2OVX A;  4JP4 A;  3B2Z A;  1UMS A;  3LMC A;  3HB2 P;  4PKQ A;  1G9K A;  1D7X A;  1AF0 A;  1BUV M;  1JAQ A;  4DPE A;  3F16 A;  1GKC A;  4GR3 A;  4QKZ A;  2L0R A;  2X3B A;  3KHI A;  3LIR A;  3NX7 A;  3RTS A;  3HDA P;  2OXU A;  1HOV A;  3DTK A;  1A85 A;  1R55 A;  2J0T A;  3GBO A;  1K7Q A;  1D5J A;  1XM5 A;  1BQO A;  3P1V A;  4GF1 A;  2AIG P;  2CLT A;  1IAC A;  4GR8 A;  2POJ A;  5H8X A;  2ERP A;  3TVC A;  1YOU A;  1G05 A;  4H49 A;  2D1O A;  3WV3 A;  3HYG A;  1BUD A;  1PWW A;  3DTI A;  1PWU A;  1JAN A;  4PKV A;  1Y0V A;  2TCL A;  5D7W A;  3HBU P;  4AYK A;  3O2X A;  1OS2 A;  2V4B A;  1KUI A;  1XFV A;  1ZXV A;  1XFZ A;  1G4K A;  5B5O A;  3EWJ A;  2OXZ A;  3DPF A;  4WKE A;  4PKR A;  1KUG A;  3EDI A;  2OW2 A;  4PKT A;  1A86 A;  3USN A;  2ERO A;  2HU6 A;  2OY4 A;  1OM6 A;  1D8M A;  4H84 A;  1AYK A;  3EDZ A;  2OY2 A;  1BSW A;  1I1I P;  1GE5 A;  1EAK A;  1XFY A;  4GQL A;  2JSD A;  1HY7 A;  1JAO A;  1MMR A;  1MNC A;  3ZUK A;  2WO8 A;  2JNP A;  1YP1 A;  1AST A;  1KUH A;  3DWB A;  3VTG A;  1SLN A;  5I4O A;  3OHL A;  5D1S A;  4XM7 A;  1EUB A;  3LJG A;  3EHY A;  1O0Q A;  4H82 A;  1BM6 A;  1FM1 A;  1CGF A;  1R1H A;  1Y8J A;  3K7N A;  1QIC A;  2DW1 A;  5L7F A;  3U1R A;  1Q3A A;  1WNI A;  4AXQ A;  3TT4 A;  3LJT A;  2E2D A;  1YCM A;  3DTE A;  1JIW P;  4CTH A;  3DPE A;  1IAB A;  1XFW A;  1CGE A;  5D1U A;  3ZVS A;  2DW0 A;  1QIB A;  4I03 A;  3LQ0 A;  3V96 B;  1MMP A;  3EDG A;  3LIK A;  4ILW D;  1CIZ A;  3KMC A;  3CKI A;  1BIW A;  1PWV A;  2MZE A;  2DDY A;  2JT6 A;  1HFS A;  1B8Y A;  2WO9 A;  3KEC A;  3LK8 A;  2X7M A;  1TVI A;  3E8R A;  1HV5 A;  5LAB A;  2YB9 A;  4XM8 A;  4FXY P;  3I7G A;  1XFX A;  1SLM A;  2RJP A;  1RM8 A;  1ZTQ A;  1GE6 A;  5B5P A;  2DDF A;  1DMT A;  2CKI A;  1GXD A;  2W14 A;  1JIZ A;  1QIA A;  4IJO A;  4PKU A;  3UVC A;  3ELM A;  1XUD A;  2OXW A;  1C8T A;  4H1Q A;  1CK7 A;  1QJI A;  2N8R A;  3HBV P;  4L7A A;  4ZR5 A;  2KRJ A;  1CAQ A;  2W12 A;  1RMZ A;  2D1N A;  1G49 A;  1KUK A;  3LE9 A;  4H30 A;  3N2V A;  3B8Z A;  1UEA A;  1SU3 A;  5D2B A;  3LEA A;  1XUC A;  3K7L A;  1C7K A;  1J7N A;  4A7B A;  3AYK A;  1IAG A;  1C3I A;  4DD8 A;  1KUF A;  4L19 A;  4EFS A;  3MA2 A;  1JH1 A;  1XUR A;  2MLR A;  1OS9 A;  1Y93 A;  1ZS0 A;  4DV8 A;  5CXA A;  5I43 A;  3P24 A;  3LQB A;  1UTZ A;  2DW2 A;  3KME A;  2YUF A;  1DTH A;  1EB6 A;  1BKC I;  1B3D A;  4Q1L A;  3LKA A;  3B92 A;  1CGL A;  1MMB A;  3TS4 A;  1SRP A;  3N2U A;  2OVZ A;  966C A;  2X3A A;  4IUW A;  1D8F A;  2USN A; 
#chains in the Genus database with same CATH homology
 1JJ9 A;  1SAT A;  3F1A A;  1IAA A;  1BQQ M;  5BOY A;  1PWQ A;  4XM6 A;  1S4B P;  1UTT A;  2K9C A;  3F17 A;  3EHX A;  1ROS A;  3WV1 A;  3BA0 A;  2XS3 A;  3SHI A;  3G42 A;  5D1T A;  1L6J A;  3KRY A;  4A3W A;  3KEJ A;  3LGP A;  4GWM A;  4H76 A;  1IAD A;  2W0D A;  4AIG A;  1O0T A;  2A8H A;  2SRT A;  1YQY A;  3G5C A;  1ZXC A;  2MZH A;  2FV5 A;  4L63 A;  4DF9 A;  2I47 A;  2ERQ A;  4I35 A;  1K7I A;  2JIH A;  1KBC A;  3HY9 A;  4PKW A;  2XS4 A;  4GWN A;  4HMA A;  456C A;  1BKC A;  2WOA A;  3LUN A;  4AUO A;  5I2Z A;  2OW1 A;  1KAP P;  1QUA A;  2W15 A;  1USN A;  4GUY A;  4FVL A;  1AKL A;  4WF6 A;  2YIG A;  5I12 A;  5L79 A;  3KEK A;  4FXQ A;  3LIL A;  3L0T A;  1QJJ A;  3LJZ A;  3DSL A;  3ZXH A;  1FLS A;  5D3C A;  3EDH A;  1HFC A;  2MZI A;  4G0D A;  3L0V A;  1OO9 A;  1PWP A;  3VI1 A;  4WZV A;  3TSK A;  4XCT A;  5JMY A;  830C A;  1ND1 A;  2Y6C A;  1JK3 A;  3KWV C;  1OMJ A;  2OZR A;  2QPJ A;  2O3E A;  4JPA A;  4H3X A;  2E3X A;  1G12 A;  3F18 A;  1R1J A;  2W13 A;  1BKC E;  2PJT A;  3OHO A;  2JT5 A;  2FV9 A;  1FBL A;  1ATL A;  3HDB A;  1ZP5 A;  4GR0 A;  2OI0 A;  2MLS A;  4J4M A;  2OW0 A;  1H71 P;  4HX3 A;  3DL1 A;  1JKY A;  1IAE A;  1R54 A;  4WK7 A;  1K7G A;  1UMT A;  1BZS A;  4JQG A;  5CZM A;  3O64 A;  2J83 A;  4JIJ A;  1ZVX A;  3F15 A;  2K2G A;  2Y6D A;  3WV2 A;  1XFU A;  2O36 A;  1JAP A;  3LUM A;  5I0L A;  1SMP A;  4L6T A;  1OM7 A;  4IN9 A;  4XBH A;  1R1I A;  2X3C A;  3RTT A;  2RJQ A;  3DNG A;  5BOT A;  3Q2G A;  4R3V A;  1CXV A;  3Q2H A;  5I3M A;  1I73 A;  4H2E A;  4JA1 A;  5BPA A;  4WKI A;  1GO8 P;  2OW9 A;  1MMQ A;  4FU4 A;  4ON1 A;  3F19 A;  2AYK A;  4G9L A;  1OM8 A;  3AIG A;  1I76 A;  3I7I A;  4PKS A;  1GO7 P;  1Z3J A;  2Z2D A;  1CQR A;  5CUH A;  1GE7 A;  1HTD A;  1GKD A;  3HY7 A;  3AYU A;  2OVX A;  4JP4 A;  3B2Z A;  1UMS A;  3LMC A;  3HB2 P;  4PKQ A;  1G9K A;  1D7X A;  1AF0 A;  1BUV M;  1JAQ A;  4DPE A;  3F16 A;  1GKC A;  4GR3 A;  4QKZ A;  2L0R A;  2X3B A;  3KHI A;  3LIR A;  3NX7 A;  3RTS A;  3HDA P;  2OXU A;  1HOV A;  3DTK A;  1A85 A;  1R55 A;  2J0T A;  3GBO A;  1K7Q A;  1D5J A;  1BQO A;  3P1V A;  4GF1 A;  2AIG P;  2CLT A;  1IAC A;  4GR8 A;  2POJ A;  5H8X A;  2ERP A;  3TVC A;  1YOU A;  1G05 A;  4H49 A;  2D1O A;  3WV3 A;  3HYG A;  1BUD A;  1PWW A;  3DTI A;  1PWU A;  1JAN A;  4PKV A;  1Y0V A;  2TCL A;  5D7W A;  3HBU P;  4AYK A;  3O2X A;  1OS2 A;  2V4B A;  1KUI A;  1XFV A;  1ZXV A;  1XFZ A;  1G4K A;  5B5O A;  3EWJ A;  2OXZ A;  3DPF A;  4WKE A;  4PKR A;  1KUG A;  3EDI A;  2OW2 A;  4PKT A;  1A86 A;  3USN A;  2ERO A;  2HU6 A;  2OY4 A;  1OM6 A;  1D8M A;  4H84 A;  1AYK A;  3EDZ A;  2OY2 A;  1BSW A;  1I1I P;  1GE5 A;  1EAK A;  1XFY A;  4GQL A;  2JSD A;  1HY7 A;  1JAO A;  1MMR A;  1MNC A;  3ZUK A;  2WO8 A;  2JNP A;  1YP1 A;  1AST A;  1KUH A;  3DWB A;  3VTG A;  1SLN A;  5I4O A;  3OHL A;  5D1S A;  4XM7 A;  1EUB A;  3LJG A;  3EHY A;  1O0Q A;  4H82 A;  1BM6 A;  1FM1 A;  1CGF A;  1R1H A;  1Y8J A;  3K7N A;  1QIC A;  2DW1 A;  5L7F A;  3U1R A;  1Q3A A;  1WNI A;  4AXQ A;  3TT4 A;  3LJT A;  2E2D A;  1YCM A;  3DTE A;  1JIW P;  4CTH A;  3DPE A;  1IAB A;  1XFW A;  1CGE A;  5D1U A;  3ZVS A;  2DW0 A;  1QIB A;  4I03 A;  3LQ0 A;  3V96 B;  1MMP A;  3EDG A;  3LIK A;  4ILW D;  1CIZ A;  3KMC A;  3CKI A;  1BIW A;  1PWV A;  2MZE A;  2DDY A;  2JT6 A;  1HFS A;  1B8Y A;  2WO9 A;  3KEC A;  3LK8 A;  2X7M A;  3E8R A;  1HV5 A;  5LAB A;  2YB9 A;  4XM8 A;  4FXY P;  3I7G A;  1XFX A;  1SLM A;  2RJP A;  1RM8 A;  1ZTQ A;  1GE6 A;  5B5P A;  2DDF A;  1DMT A;  2CKI A;  1GXD A;  2W14 A;  1JIZ A;  1QIA A;  4IJO A;  4PKU A;  3UVC A;  3ELM A;  1XUD A;  2OXW A;  1C8T A;  4H1Q A;  1CK7 A;  1QJI A;  2N8R A;  3HBV P;  4L7A A;  4ZR5 A;  2KRJ A;  1CAQ A;  2W12 A;  1RMZ A;  2D1N A;  1G49 A;  1KUK A;  3LE9 A;  4H30 A;  3N2V A;  3B8Z A;  1UEA A;  1SU3 A;  5D2B A;  3LEA A;  1XUC A;  3K7L A;  1C7K A;  1J7N A;  4A7B A;  3AYK A;  1IAG A;  1C3I A;  4DD8 A;  1KUF A;  4L19 A;  4EFS A;  3MA2 A;  1JH1 A;  1XUR A;  2MLR A;  1OS9 A;  1Y93 A;  1ZS0 A;  4DV8 A;  5CXA A;  5I43 A;  3P24 A;  3LQB A;  1UTZ A;  2DW2 A;  3KME A;  2YUF A;  1DTH A;  1EB6 A;  1BKC I;  1B3D A;  4Q1L A;  3LKA A;  3B92 A;  1CGL A;  1MMB A;  3TS4 A;  1SRP A;  3N2U A;  2OVZ A;  966C A;  2X3A A;  4IUW A;  1D8F A;  2USN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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