3Q2HA

Adamts1 in complex with n-hydroxyformamide inhibitors of adam-ts4
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
296
structure length
284
Chain Sequence
SHRYVETMLVADQSMAEFHGSGLKHYLLTLFSVAARLYKHPSIRNSVSLVVVKILVIHDEQKGPEVTSNAALTLRNFCNWQKQHNPPSDRDAEHYDTAILFTRQDLCGSQTCDTLGMADVGTVCDPSRSCSVIEDDGLQAAFTTAHELGHVFNMPHDDAKQCASLNDSHMMASMLSNLDHSQPWSPCSAYMITSFLDNGHGECLMDKPQNPIQLPGDLPGTSYDANRQCQFTFGEDSKHCPTCSTLWCTGVLVCQTKHFPWADGTSCGEGKWCINGKCVNKLVP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The design and synthesis of novel N-hydroxyformamide inhibitors of ADAM-TS4 for the treatment of osteoarthritis
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords A disintegrin and metalloproteinase with thrombospondin moti
total genus 91
structure length 284
sequence length 296
chains with identical sequence B
ec nomenclature ec 3.4.24.-:
pdb deposition date 2010-12-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01421 Reprolysin Reprolysin (M12B) family zinc metalloprotease
A PF17771 ADAM_CR_2 ADAM cysteine-rich domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3q2hA01
4DPEA 1GXDA 1CAQA 3TVCA 2V4BA 1ZTQA 1BKCI 4A7BA 2ERQA 1BQQM 1MMRA 1PWWA 3KEJA 4WKIA 1UMSA 1L6JA 3EWJA 1MMQA 3P1VA 3KECA 2J0TA 3GBOA 1FM1A 4JPAA 3G42A 1JK3A 1SLMA 4L63A 1YP1A 4ILWD 1C7KA 2MLSA 3ELMA 1BZSA 456CA 2K9CA 3EDGA 1BUVM 1AF0A 4CTHA 4Q1LA 3B2ZA 4H76A 1ZXVA 2CLTA 1R54A 1Y93A 1JAQA 4DD8A 2L0RA 1ASTA 5CUHA 5BOTA 2OY4A 1QIAA 3USNA 2USNA 5LABA 3LUMA 2OY2A 4PKVA 3MA2A 4FXYP 1ATLA 1BIWA 3L0TA 4ON1A 4PKUA 3TSKA 3LGPA 5D2BA 1H71P 2KRJA 1K7GA 3ZXHA 1OM6A 4GUYA 4XBHA 4I35A 1XURA 1MNCA 2DDYA 1MMPA 4GQLA 4XM6A 4PKSA 5D7WA 2AIGP 1IAAA 1UEAA 4IN9A 1JH1A 2OW2A 2W14A 4GF1A 1ZVXA 1D8MA 1XFXA 1Z3JA 1SU3A 4PKRA 2E2DA 1XFVA 2X7MA 4AYKA 1CK7A 4H82A 4DV8A 4H3XA 1YCMA 3K7NA 1FLSA 5I4OA 1JJ9A 3N2UA 3KWVC 1GKDA 3WV2A 1I76A 4H30A 3LJTA 1J7NA 2OW9A 1QIBA 2OXZA 1IABA 1JANA 830CA 1IACA 2JSDA 4XM8A 4L6TA 1YQYA 2RJQA 4FXQA 3OHLA 5L79A 1KBCA 2DDFA 3U1RA 2XS4A 2YIGA 3LMCA 3CKIA 3HY9A 3LIKA 3LK8A 3DPFA 3DNGA 1GE5A 1R1IA 1PWPA 4JA1A 1SLNA 1FBLA 4IJOA 1GE6A 1SATA 4GWNA 2I47A 3BA0A 5D1SA 1ZP5A 3F1AA 1KUKA 4AIGA 4A3WA 1CIZA 4H49A 5D1TA 1A86A 2MZEA 1EB6A 1QJJA 3KMEA 3VTGA 1XFZA 1KAPP 3EDHA 1Y8JA 3KMCA 3HDBA 2OVZA 1PWQA 4XCTA 1YOUA 3DPEA 2Z2DA 3I7IA 3LEAA 1HOVA 1XUCA 2X3BA 2W12A 2W13A 2D1NA 1QJIA 5BOYA 3HY7A 4GR3A 3RTTA 3SHIA 3F19A 2N8RA 1B3DA 1BUDA 1KUFA 2WO9A 5L7FA 2K2GA 3EDIA 1USNA 3I7GA 2JIHA 3DL1A 1JAPA 1OMJA 1KUIA 4IUWA 2WO8A 1DMTA 2DW2A 4JQGA 1ROSA 1KUHA 3EHYA 1EAKA 2CKIA 3LQ0A 2YB9A 2W0DA 4GR8A 1R1JA 1SMPA 3OHOA 5I0LA 4DF9A 3HB2P 4PKQA 1CGEA 2X3AA 2FV5A 1JIWP 1XFWA 1IAGA 1HTDA 5I43A 2OXUA 1Q3AA 3RTSA 2OI0A 1R1HA 966CA 4PKWA 1DTHA 1GO7P 3P24A 2POJA 4GWMA 2MZIA 1RM8A 3LJZA 1I1IP 3F17A 3TT4A 4HX3A 1B8YA 2AYKA 2SRTA 1PWVA 1HFCA 4HMAA 4FU4A 1OO9A 2Y6DA 2RJPA 2WOAA 1CGLA 1CGFA 4WKEA 4GR0A 1XUDA 3O64A 3F18A 2A8HA 3AYUA 3KEKA 1R55A 4EFSA 2JNPA 5D1UA 1BM6A 3B92A 5BPAA 1AYKA 1GKCA 3HYGA 2MLRA 1G12A 1G4KA 1RMZA 3LJGA 1UTZA 1G49A 4H2EA 1D7XA 1S4BP 1SRPA 5B5OA 1BSWA 3LE9A 2Y6CA 3B8ZA 1HY7A 1ZS0A 4H1QA 1A85A 4G0DA 3LKAA 1OM7A 2ERPA 3HBUP 2DW1A 1KUGA 1MMBA 3KRYA 4ZR5A 4J4MA 5D3CA 3DWBA 1CQRA 3LILA 3LIRA 2OXWA 2OW1A 1BQOA 1XFUA 1O0QA 3V96B 3Q2GA 1K7QA 3F16A 1C8TA 3LQBA 3E8RA 5I2ZA 3HDAP 1OM8A 1IAEA 1D5JA 1HV5A 1EUBA 4H84A 2X3CA 4WF6A 1BKCA 4XM7A 5I12A 4WZVA 2TCLA 3KHIA 5CZMA 1CXVA 1JIZA 1UMTA 4G9LA 3EDZA 1ND1A 2O36A 2QPJA 4PKTA 1K7IA 1OS2A 5CXAA 3ZUKA 5H8XA 1GE7A 4R3VA 3O2XA 1G05A 3WV1A 5I3MA 3Q2HA 2FV9A 3HBVP 2DW0A 2MZHA 3VI1A 3ZVSA 2HU6A 3WV3A 1Y0VA 1PWUA 3LUNA 2JT5A 1HFSA 1XFYA 1OS9A 2D1OA 2OVXA 1UTTA 1WNIA 2PJTA 1O0TA 1C3IA 4JIJA 2OW0A 4L19A 1ZXCA 4I03A 3K7LA 1IADA 1QICA 2E3XA 2OZRA 1JAOA 2XS3A 5JMYA 2O3EA 3AYKA 4AUOA 3DSLA 1D8FA 2EROA 3G5CA 4AXQA 5B5PA 1GO8P 3UVCA 3F15A 3L0VA 2JT6A 2J83A 4QKZA 1I73A 1G9KA 1QUAA 1BKCE 1JKYA 3NX7A 3AIGA 4WK7A 4JP4A 2W15A 3TS4A 1AKLA 3N2VA 4FVLA 3EHXA
chains in the Genus database with same CATH superfamily
4DPEA 1GXDA 1CAQA 3TVCA 2V4BA 1ZTQA 1BKCI 4A7BA 2ERQA 1BQQM 1MMRA 1PWWA 3KEJA 4WKIA 1UMSA 1L6JA 3EWJA 1MMQA 3P1VA 3KECA 2J0TA 3GBOA 1FM1A 4JPAA 3G42A 1JK3A 1SLMA 4L63A 2YUFA 1YP1A 4ILWD 1C7KA 2MLSA 3ELMA 1BZSA 456CA 2K9CA 3EDGA 1BUVM 1AF0A 4CTHA 4Q1LA 3B2ZA 4H76A 1ZXVA 2CLTA 1R54A 1Y93A 1JAQA 4DD8A 2L0RA 1ASTA 5CUHA 5BOTA 2OY4A 1QIAA 3USNA 2USNA 5LABA 3LUMA 2OY2A 4PKVA 3MA2A 4FXYP 1ATLA 1BIWA 3L0TA 4ON1A 4PKUA 3TSKA 3LGPA 5D2BA 1H71P 2KRJA 1K7GA 3ZXHA 1OM6A 4GUYA 3DTKA 4XBHA 4I35A 1XURA 1OZ9A 1MNCA 2DDYA 1MMPA 4GQLA 4XM6A 4PKSA 5D7WA 2AIGP 1IAAA 1UEAA 4IN9A 1JH1A 2OW2A 2W14A 4GF1A 1ZVXA 1D8MA 1XFXA 1Z3JA 1SU3A 4PKRA 2E2DA 1XFVA 2X7MA 4AYKA 1CK7A 1XAXA 4H82A 4DV8A 4H3XA 1YCMA 3K7NA 1FLSA 5I4OA 1JJ9A 3N2UA 3KWVC 1GKDA 3WV2A 1I76A 4H30A 3LJTA 1J7NA 2OW9A 1QIBA 2OXZA 1IABA 1JANA 830CA 1IACA 2JSDA 4XM8A 4L6TA 1YQYA 2RJQA 4FXQA 3OHLA 5L79A 1KBCA 2DDFA 3U1RA 2XS4A 2YIGA 3LMCA 3CKIA 3HY9A 3LIKA 3LK8A 3DPFA 3DNGA 1GE5A 1R1IA 1PWPA 4JA1A 1SLNA 1FBLA 4IJOA 1GE6A 1SATA 4GWNA 2I47A 3BA0A 5D1SA 1ZP5A 3F1AA 1KUKA 4AIGA 4A3WA 1CIZA 4H49A 5D1TA 1A86A 2MZEA 1EB6A 1QJJA 3KMEA 3VTGA 1XFZA 1KAPP 3EDHA 1Y8JA 3KMCA 3HDBA 2OVZA 1PWQA 4XCTA 1YOUA 3DPEA 2Z2DA 3I7IA 3LEAA 1HOVA 1XUCA 2X3BA 2W12A 2W13A 3DTIA 2D1NA 1QJIA 5BOYA 3HY7A 4GR3A 3RTTA 3SHIA 3F19A 2N8RA 1B3DA 1BUDA 1KUFA 2WO9A 5L7FA 2K2GA 3EDIA 1USNA 3I7GA 2JIHA 3DL1A 1JAPA 1OMJA 1KUIA 4IUWA 2WO8A 1DMTA 2DW2A 4JQGA 1ROSA 1KUHA 3EHYA 1EAKA 2CKIA 3LQ0A 2YB9A 2W0DA 4GR8A 1R1JA 1SMPA 3OHOA 5I0LA 4DF9A 3HB2P 4PKQA 1XM5A 1CGEA 2X3AA 2FV5A 1JIWP 1XFWA 1IAGA 1HTDA 5I43A 2OXUA 1Q3AA 3RTSA 2OI0A 1R1HA 966CA 4PKWA 1DTHA 1GO7P 3P24A 2POJA 4GWMA 2MZIA 1RM8A 3LJZA 1I1IP 3F17A 3TT4A 4HX3A 1B8YA 2AYKA 2SRTA 1PWVA 1HFCA 4HMAA 4FU4A 1OO9A 2Y6DA 2RJPA 2WOAA 3DTEA 1CGLA 1CGFA 4WKEA 4GR0A 1XUDA 3O64A 3F18A 2A8HA 3AYUA 3KEKA 1R55A 4EFSA 2JNPA 5D1UA 1BM6A 3B92A 5BPAA 1AYKA 1GKCA 3HYGA 2MLRA 1G12A 1G4KA 1RMZA 3LJGA 1UTZA 1G49A 4H2EA 1D7XA 1S4BP 1SRPA 5B5OA 1BSWA 3LE9A 2Y6CA 3B8ZA 1HY7A 1ZS0A 4H1QA 1A85A 4G0DA 3LKAA 1OM7A 2ERPA 3HBUP 2DW1A 1KUGA 1MMBA 3KRYA 4ZR5A 4J4MA 5D3CA 3DWBA 1CQRA 3LILA 3LIRA 2OXWA 2OW1A 1BQOA 1XFUA 1O0QA 3V96B 3Q2GA 1K7QA 3F16A 1C8TA 3LQBA 3E8RA 5I2ZA 3HDAP 1OM8A 1IAEA 1D5JA 1HV5A 1EUBA 4H84A 2X3CA 4WF6A 1BKCA 4XM7A 5I12A 4WZVA 2TCLA 3KHIA 5CZMA 1CXVA 1JIZA 1UMTA 4G9LA 3EDZA 1ND1A 2O36A 2QPJA 4PKTA 1K7IA 1OS2A 5CXAA 4L7AA 3ZUKA 5H8XA 1GE7A 4R3VA 3O2XA 1G05A 3WV1A 5I3MA 3Q2HA 2FV9A 3HBVP 2DW0A 2MZHA 3VI1A 3ZVSA 2HU6A 3WV3A 1Y0VA 1PWUA 3LUNA 2JT5A 1HFSA 1TVIA 1XFYA 1OS9A 2D1OA 2OVXA 1UTTA 1WNIA 2PJTA 1O0TA 1C3IA 4JIJA 2OW0A 4L19A 1ZXCA 4I03A 3K7LA 1IADA 1QICA 2E3XA 2OZRA 1JAOA 2XS3A 5JMYA 2O3EA 3AYKA 4AUOA 3DSLA 1D8FA 2EROA 3G5CA 4AXQA 5B5PA 1GO8P 3UVCA 3F15A 3L0VA 2JT6A 2J83A 4QKZA 1I73A 1G9KA 1QUAA 1BKCE 1JKYA 3NX7A 3AIGA 4WK7A 4JP4A 2W15A 3TS4A 1AKLA 3N2VA 4FVLA 3EHXA
chains in the Genus database with same CATH topology
4DPEA 1GXDA 1CAQA 3TVCA 2V4BA 1ZTQA 1BKCI 4A7BA 2ERQA 1BQQM 1MMRA 1PWWA 3KEJA 4WKIA 1UMSA 1L6JA 3EWJA 1MMQA 3P1VA 3KECA 2J0TA 3GBOA 1FM1A 4JPAA 3G42A 1JK3A 1SLMA 4L63A 2YUFA 1YP1A 4ILWD 1C7KA 2MLSA 3ELMA 1BZSA 456CA 2K9CA 3EDGA 1BUVM 1AF0A 4CTHA 4Q1LA 3B2ZA 4H76A 1ZXVA 2CLTA 1R54A 1Y93A 1JAQA 4DD8A 2L0RA 1ASTA 5CUHA 5BOTA 2OY4A 1QIAA 3USNA 2USNA 5LABA 3LUMA 2OY2A 4PKVA 3MA2A 4FXYP 1ATLA 1BIWA 3L0TA 4ON1A 4PKUA 3TSKA 3LGPA 5D2BA 1H71P 2KRJA 1K7GA 3ZXHA 1OM6A 4GUYA 3DTKA 4XBHA 4I35A 1XURA 1MNCA 2DDYA 1MMPA 4GQLA 4XM6A 4PKSA 5D7WA 2AIGP 1IAAA 1UEAA 4IN9A 1JH1A 2OW2A 2W14A 4GF1A 1ZVXA 1D8MA 1XFXA 1Z3JA 1SU3A 4PKRA 2E2DA 1XFVA 2X7MA 4AYKA 1CK7A 4H82A 4DV8A 4H3XA 1YCMA 3K7NA 1FLSA 5I4OA 1JJ9A 3N2UA 3KWVC 1GKDA 3WV2A 1I76A 4H30A 3LJTA 1J7NA 2OW9A 1QIBA 2OXZA 1IABA 1JANA 830CA 1IACA 2JSDA 4XM8A 4L6TA 1YQYA 2RJQA 4FXQA 3OHLA 5L79A 1KBCA 2DDFA 3U1RA 2XS4A 2YIGA 3LMCA 3CKIA 3HY9A 3LIKA 3LK8A 3DPFA 3DNGA 1GE5A 1R1IA 1PWPA 4JA1A 1SLNA 1FBLA 4IJOA 1GE6A 1SATA 4GWNA 2I47A 3BA0A 5D1SA 1ZP5A 3F1AA 1KUKA 4AIGA 4A3WA 1CIZA 4H49A 5D1TA 1A86A 2MZEA 1EB6A 1QJJA 3KMEA 3VTGA 1XFZA 1KAPP 3EDHA 1Y8JA 3KMCA 3HDBA 2OVZA 1PWQA 4XCTA 1YOUA 3DPEA 2Z2DA 3I7IA 3LEAA 1HOVA 1XUCA 2X3BA 2W12A 2W13A 3DTIA 2D1NA 1QJIA 5BOYA 3HY7A 4GR3A 3RTTA 3SHIA 3F19A 2N8RA 1B3DA 1BUDA 1KUFA 2WO9A 5L7FA 2K2GA 3EDIA 1USNA 3I7GA 2JIHA 3DL1A 1JAPA 1OMJA 1KUIA 4IUWA 2WO8A 1DMTA 2DW2A 4JQGA 1ROSA 1KUHA 3EHYA 1EAKA 2CKIA 3LQ0A 2YB9A 2W0DA 4GR8A 1R1JA 1SMPA 3OHOA 5I0LA 4DF9A 3HB2P 4PKQA 1CGEA 2X3AA 2FV5A 1JIWP 1XFWA 1IAGA 1HTDA 5I43A 2OXUA 1Q3AA 3RTSA 2OI0A 1R1HA 966CA 4PKWA 1DTHA 1GO7P 3P24A 2POJA 4GWMA 2MZIA 1RM8A 3LJZA 1I1IP 3F17A 3TT4A 4HX3A 1B8YA 2AYKA 2SRTA 1PWVA 1HFCA 4HMAA 4FU4A 1OO9A 2Y6DA 2RJPA 2WOAA 3DTEA 1CGLA 1CGFA 4WKEA 4GR0A 1XUDA 3O64A 3F18A 2A8HA 3AYUA 3KEKA 1R55A 4EFSA 2JNPA 5D1UA 1BM6A 3B92A 5BPAA 1AYKA 1GKCA 3HYGA 2MLRA 1G12A 1G4KA 1RMZA 3LJGA 1UTZA 1G49A 4H2EA 1D7XA 1S4BP 1SRPA 5B5OA 1BSWA 3LE9A 2Y6CA 3B8ZA 1HY7A 1ZS0A 4H1QA 1A85A 4G0DA 3LKAA 1OM7A 2ERPA 3HBUP 2DW1A 1KUGA 1MMBA 3KRYA 4ZR5A 4J4MA 5D3CA 3DWBA 1CQRA 3LILA 3LIRA 2OXWA 2OW1A 1BQOA 1XFUA 1O0QA 3V96B 3Q2GA 1K7QA 3F16A 1C8TA 3LQBA 3E8RA 5I2ZA 3HDAP 1OM8A 1IAEA 1D5JA 1HV5A 1EUBA 4H84A 2X3CA 4WF6A 1BKCA 4XM7A 5I12A 4WZVA 2TCLA 3KHIA 5CZMA 1CXVA 1JIZA 1UMTA 4G9LA 3EDZA 1ND1A 2O36A 2QPJA 4PKTA 1K7IA 1OS2A 5CXAA 4L7AA 3ZUKA 5H8XA 1GE7A 4R3VA 3O2XA 1G05A 3WV1A 5I3MA 3Q2HA 2FV9A 3HBVP 2DW0A 2MZHA 3VI1A 3ZVSA 2HU6A 3WV3A 1Y0VA 1PWUA 3LUNA 2JT5A 1HFSA 1XFYA 1OS9A 2D1OA 2OVXA 1UTTA 1WNIA 2PJTA 1O0TA 1C3IA 4JIJA 2OW0A 4L19A 1ZXCA 4I03A 3K7LA 1IADA 1QICA 2E3XA 2OZRA 1JAOA 2XS3A 5JMYA 2O3EA 3AYKA 4AUOA 3DSLA 1D8FA 2EROA 3G5CA 4AXQA 5B5PA 1GO8P 3UVCA 3F15A 3L0VA 2JT6A 2J83A 4QKZA 1I73A 1G9KA 1QUAA 1BKCE 1JKYA 3NX7A 3AIGA 4WK7A 4JP4A 2W15A 3TS4A 1AKLA 3N2VA 4FVLA 3EHXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DPE A;  1GXD A;  1CAQ A;  3TVC A;  2V4B A;  1ZTQ A;  1BKC I;  4A7B A;  2ERQ A;  1BQQ M;  1MMR A;  1PWW A;  3KEJ A;  4WKI A;  1UMS A;  1L6J A;  3EWJ A;  1MMQ A;  3P1V A;  3KEC A;  2J0T A;  3GBO A;  1FM1 A;  4JPA A;  3G42 A;  1JK3 A;  1SLM A;  4L63 A;  1YP1 A;  4ILW D;  1C7K A;  2MLS A;  3ELM A;  1BZS A;  456C A;  2K9C A;  3EDG A;  1BUV M;  1AF0 A;  4CTH A;  4Q1L A;  3B2Z A;  4H76 A;  1ZXV A;  2CLT A;  1R54 A;  1Y93 A;  1JAQ A;  4DD8 A;  2L0R A;  1AST A;  5CUH A;  5BOT A;  2OY4 A;  1QIA A;  3USN A;  2USN A;  5LAB A;  3LUM A;  2OY2 A;  4PKV A;  3MA2 A;  4FXY P;  1ATL A;  1BIW A;  3L0T A;  4ON1 A;  4PKU A;  3TSK A;  3LGP A;  5D2B A;  1H71 P;  2KRJ A;  1K7G A;  3ZXH A;  1OM6 A;  4GUY A;  4XBH A;  4I35 A;  1XUR A;  1MNC A;  2DDY A;  1MMP A;  4GQL A;  4XM6 A;  4PKS A;  5D7W A;  2AIG P;  1IAA A;  1UEA A;  4IN9 A;  1JH1 A;  2OW2 A;  2W14 A;  4GF1 A;  1ZVX A;  1D8M A;  1XFX A;  1Z3J A;  1SU3 A;  4PKR A;  2E2D A;  1XFV A;  2X7M A;  4AYK A;  1CK7 A;  4H82 A;  4DV8 A;  4H3X A;  1YCM A;  3K7N A;  1FLS A;  5I4O A;  1JJ9 A;  3N2U A;  3KWV C;  1GKD A;  3WV2 A;  1I76 A;  4H30 A;  3LJT A;  1J7N A;  2OW9 A;  1QIB A;  2OXZ A;  1IAB A;  1JAN A;  830C A;  1IAC A;  2JSD A;  4XM8 A;  4L6T A;  1YQY A;  2RJQ A;  4FXQ A;  3OHL A;  5L79 A;  1KBC A;  2DDF A;  3U1R A;  2XS4 A;  2YIG A;  3LMC A;  3CKI A;  3HY9 A;  3LIK A;  3LK8 A;  3DPF A;  3DNG A;  1GE5 A;  1R1I A;  1PWP A;  4JA1 A;  1SLN A;  1FBL A;  4IJO A;  1GE6 A;  1SAT A;  4GWN A;  2I47 A;  3BA0 A;  5D1S A;  1ZP5 A;  3F1A A;  1KUK A;  4AIG A;  4A3W A;  1CIZ A;  4H49 A;  5D1T A;  1A86 A;  2MZE A;  1EB6 A;  1QJJ A;  3KME A;  3VTG A;  1XFZ A;  1KAP P;  3EDH A;  1Y8J A;  3KMC A;  3HDB A;  2OVZ A;  1PWQ A;  4XCT A;  1YOU A;  3DPE A;  2Z2D A;  3I7I A;  3LEA A;  1HOV A;  1XUC A;  2X3B A;  2W12 A;  2W13 A;  2D1N A;  1QJI A;  5BOY A;  3HY7 A;  4GR3 A;  3RTT A;  3SHI A;  3F19 A;  2N8R A;  1B3D A;  1BUD A;  1KUF A;  2WO9 A;  5L7F A;  2K2G A;  3EDI A;  1USN A;  3I7G A;  2JIH A;  3DL1 A;  1JAP A;  1OMJ A;  1KUI A;  4IUW A;  2WO8 A;  1DMT A;  2DW2 A;  4JQG A;  1ROS A;  1KUH A;  3EHY A;  1EAK A;  2CKI A;  3LQ0 A;  2YB9 A;  2W0D A;  4GR8 A;  1R1J A;  1SMP A;  3OHO A;  5I0L A;  4DF9 A;  3HB2 P;  4PKQ A;  1CGE A;  2X3A A;  2FV5 A;  1JIW P;  1XFW A;  1IAG A;  1HTD A;  5I43 A;  2OXU A;  1Q3A A;  3RTS A;  2OI0 A;  1R1H A;  966C A;  4PKW A;  1DTH A;  1GO7 P;  3P24 A;  2POJ A;  4GWM A;  2MZI A;  1RM8 A;  3LJZ A;  1I1I P;  3F17 A;  3TT4 A;  4HX3 A;  1B8Y A;  2AYK A;  2SRT A;  1PWV A;  1HFC A;  4HMA A;  4FU4 A;  1OO9 A;  2Y6D A;  2RJP A;  2WOA A;  1CGL A;  1CGF A;  4WKE A;  4GR0 A;  1XUD A;  3O64 A;  3F18 A;  2A8H A;  3AYU A;  3KEK A;  1R55 A;  4EFS A;  2JNP A;  5D1U A;  1BM6 A;  3B92 A;  5BPA A;  1AYK A;  1GKC A;  3HYG A;  2MLR A;  1G12 A;  1G4K A;  1RMZ A;  3LJG A;  1UTZ A;  1G49 A;  4H2E A;  1D7X A;  1S4B P;  1SRP A;  5B5O A;  1BSW A;  3LE9 A;  2Y6C A;  3B8Z A;  1HY7 A;  1ZS0 A;  4H1Q A;  1A85 A;  4G0D A;  3LKA A;  1OM7 A;  2ERP A;  3HBU P;  2DW1 A;  1KUG A;  1MMB A;  3KRY A;  4ZR5 A;  4J4M A;  5D3C A;  3DWB A;  1CQR A;  3LIL A;  3LIR A;  2OXW A;  2OW1 A;  1BQO A;  1XFU A;  1O0Q A;  3V96 B;  3Q2G A;  1K7Q A;  3F16 A;  1C8T A;  3LQB A;  3E8R A;  5I2Z A;  3HDA P;  1OM8 A;  1IAE A;  1D5J A;  1HV5 A;  1EUB A;  4H84 A;  2X3C A;  4WF6 A;  1BKC A;  4XM7 A;  5I12 A;  4WZV A;  2TCL A;  3KHI A;  5CZM A;  1CXV A;  1JIZ A;  1UMT A;  4G9L A;  3EDZ A;  1ND1 A;  2O36 A;  2QPJ A;  4PKT A;  1K7I A;  1OS2 A;  5CXA A;  3ZUK A;  5H8X A;  1GE7 A;  4R3V A;  3O2X A;  1G05 A;  3WV1 A;  5I3M A;  3Q2H A;  2FV9 A;  3HBV P;  2DW0 A;  2MZH A;  3VI1 A;  3ZVS A;  2HU6 A;  3WV3 A;  1Y0V A;  1PWU A;  3LUN A;  2JT5 A;  1HFS A;  1XFY A;  1OS9 A;  2D1O A;  2OVX A;  1UTT A;  1WNI A;  2PJT A;  1O0T A;  1C3I A;  4JIJ A;  2OW0 A;  4L19 A;  1ZXC A;  4I03 A;  3K7L A;  1IAD A;  1QIC A;  2E3X A;  2OZR A;  1JAO A;  2XS3 A;  5JMY A;  2O3E A;  3AYK A;  4AUO A;  3DSL A;  1D8F A;  2ERO A;  3G5C A;  4AXQ A;  5B5P A;  1GO8 P;  3UVC A;  3F15 A;  3L0V A;  2JT6 A;  2J83 A;  4QKZ A;  1I73 A;  1G9K A;  1QUA A;  1BKC E;  1JKY A;  3NX7 A;  3AIG A;  4WK7 A;  4JP4 A;  2W15 A;  3TS4 A;  1AKL A;  3N2V A;  4FVL A;  3EHX A; 
#chains in the Genus database with same CATH topology
 4DPE A;  1GXD A;  1CAQ A;  3TVC A;  2V4B A;  1ZTQ A;  1BKC I;  4A7B A;  2ERQ A;  1BQQ M;  1MMR A;  1PWW A;  3KEJ A;  4WKI A;  1UMS A;  1L6J A;  3EWJ A;  1MMQ A;  3P1V A;  3KEC A;  2J0T A;  3GBO A;  1FM1 A;  4JPA A;  3G42 A;  1JK3 A;  1SLM A;  4L63 A;  2YUF A;  1YP1 A;  4ILW D;  1C7K A;  2MLS A;  3ELM A;  1BZS A;  456C A;  2K9C A;  3EDG A;  1BUV M;  1AF0 A;  4CTH A;  4Q1L A;  3B2Z A;  4H76 A;  1ZXV A;  2CLT A;  1R54 A;  1Y93 A;  1JAQ A;  4DD8 A;  2L0R A;  1AST A;  5CUH A;  5BOT A;  2OY4 A;  1QIA A;  3USN A;  2USN A;  5LAB A;  3LUM A;  2OY2 A;  4PKV A;  3MA2 A;  4FXY P;  1ATL A;  1BIW A;  3L0T A;  4ON1 A;  4PKU A;  3TSK A;  3LGP A;  5D2B A;  1H71 P;  2KRJ A;  1K7G A;  3ZXH A;  1OM6 A;  4GUY A;  3DTK A;  4XBH A;  4I35 A;  1XUR A;  1OZ9 A;  1MNC A;  2DDY A;  1MMP A;  4GQL A;  4XM6 A;  4PKS A;  5D7W A;  2AIG P;  1IAA A;  1UEA A;  4IN9 A;  1JH1 A;  2OW2 A;  2W14 A;  4GF1 A;  1ZVX A;  1D8M A;  1XFX A;  1Z3J A;  1SU3 A;  4PKR A;  2E2D A;  1XFV A;  2X7M A;  4AYK A;  1CK7 A;  1XAX A;  4H82 A;  4DV8 A;  4H3X A;  1YCM A;  3K7N A;  1FLS A;  5I4O A;  1JJ9 A;  3N2U A;  3KWV C;  1GKD A;  3WV2 A;  1I76 A;  4H30 A;  3LJT A;  1J7N A;  2OW9 A;  1QIB A;  2OXZ A;  1IAB A;  1JAN A;  830C A;  1IAC A;  2JSD A;  4XM8 A;  4L6T A;  1YQY A;  2RJQ A;  4FXQ A;  3OHL A;  5L79 A;  1KBC A;  2DDF A;  3U1R A;  2XS4 A;  2YIG A;  3LMC A;  3CKI A;  3HY9 A;  3LIK A;  3LK8 A;  3DPF A;  3DNG A;  1GE5 A;  1R1I A;  1PWP A;  4JA1 A;  1SLN A;  1FBL A;  4IJO A;  1GE6 A;  1SAT A;  4GWN A;  2I47 A;  3BA0 A;  5D1S A;  1ZP5 A;  3F1A A;  1KUK A;  4AIG A;  4A3W A;  1CIZ A;  4H49 A;  5D1T A;  1A86 A;  2MZE A;  1EB6 A;  1QJJ A;  3KME A;  3VTG A;  1XFZ A;  1KAP P;  3EDH A;  1Y8J A;  3KMC A;  3HDB A;  2OVZ A;  1PWQ A;  4XCT A;  1YOU A;  3DPE A;  2Z2D A;  3I7I A;  3LEA A;  1HOV A;  1XUC A;  2X3B A;  2W12 A;  2W13 A;  3DTI A;  2D1N A;  1QJI A;  5BOY A;  3HY7 A;  4GR3 A;  3RTT A;  3SHI A;  3F19 A;  2N8R A;  1B3D A;  1BUD A;  1KUF A;  2WO9 A;  5L7F A;  2K2G A;  3EDI A;  1USN A;  3I7G A;  2JIH A;  3DL1 A;  1JAP A;  1OMJ A;  1KUI A;  4IUW A;  2WO8 A;  1DMT A;  2DW2 A;  4JQG A;  1ROS A;  1KUH A;  3EHY A;  1EAK A;  2CKI A;  3LQ0 A;  2YB9 A;  2W0D A;  4GR8 A;  1R1J A;  1SMP A;  3OHO A;  5I0L A;  4DF9 A;  3HB2 P;  4PKQ A;  1XM5 A;  1CGE A;  2X3A A;  2FV5 A;  1JIW P;  1XFW A;  1IAG A;  1HTD A;  5I43 A;  2OXU A;  1Q3A A;  3RTS A;  2OI0 A;  1R1H A;  966C A;  4PKW A;  1DTH A;  1GO7 P;  3P24 A;  2POJ A;  4GWM A;  2MZI A;  1RM8 A;  3LJZ A;  1I1I P;  3F17 A;  3TT4 A;  4HX3 A;  1B8Y A;  2AYK A;  2SRT A;  1PWV A;  1HFC A;  4HMA A;  4FU4 A;  1OO9 A;  2Y6D A;  2RJP A;  2WOA A;  3DTE A;  1CGL A;  1CGF A;  4WKE A;  4GR0 A;  1XUD A;  3O64 A;  3F18 A;  2A8H A;  3AYU A;  3KEK A;  1R55 A;  4EFS A;  2JNP A;  5D1U A;  1BM6 A;  3B92 A;  5BPA A;  1AYK A;  1GKC A;  3HYG A;  2MLR A;  1G12 A;  1G4K A;  1RMZ A;  3LJG A;  1UTZ A;  1G49 A;  4H2E A;  1D7X A;  1S4B P;  1SRP A;  5B5O A;  1BSW A;  3LE9 A;  2Y6C A;  3B8Z A;  1HY7 A;  1ZS0 A;  4H1Q A;  1A85 A;  4G0D A;  3LKA A;  1OM7 A;  2ERP A;  3HBU P;  2DW1 A;  1KUG A;  1MMB A;  3KRY A;  4ZR5 A;  4J4M A;  5D3C A;  3DWB A;  1CQR A;  3LIL A;  3LIR A;  2OXW A;  2OW1 A;  1BQO A;  1XFU A;  1O0Q A;  3V96 B;  3Q2G A;  1K7Q A;  3F16 A;  1C8T A;  3LQB A;  3E8R A;  5I2Z A;  3HDA P;  1OM8 A;  1IAE A;  1D5J A;  1HV5 A;  1EUB A;  4H84 A;  2X3C A;  4WF6 A;  1BKC A;  4XM7 A;  5I12 A;  4WZV A;  2TCL A;  3KHI A;  5CZM A;  1CXV A;  1JIZ A;  1UMT A;  4G9L A;  3EDZ A;  1ND1 A;  2O36 A;  2QPJ A;  4PKT A;  1K7I A;  1OS2 A;  5CXA A;  4L7A A;  3ZUK A;  5H8X A;  1GE7 A;  4R3V A;  3O2X A;  1G05 A;  3WV1 A;  5I3M A;  3Q2H A;  2FV9 A;  3HBV P;  2DW0 A;  2MZH A;  3VI1 A;  3ZVS A;  2HU6 A;  3WV3 A;  1Y0V A;  1PWU A;  3LUN A;  2JT5 A;  1HFS A;  1TVI A;  1XFY A;  1OS9 A;  2D1O A;  2OVX A;  1UTT A;  1WNI A;  2PJT A;  1O0T A;  1C3I A;  4JIJ A;  2OW0 A;  4L19 A;  1ZXC A;  4I03 A;  3K7L A;  1IAD A;  1QIC A;  2E3X A;  2OZR A;  1JAO A;  2XS3 A;  5JMY A;  2O3E A;  3AYK A;  4AUO A;  3DSL A;  1D8F A;  2ERO A;  3G5C A;  4AXQ A;  5B5P A;  1GO8 P;  3UVC A;  3F15 A;  3L0V A;  2JT6 A;  2J83 A;  4QKZ A;  1I73 A;  1G9K A;  1QUA A;  1BKC E;  1JKY A;  3NX7 A;  3AIG A;  4WK7 A;  4JP4 A;  2W15 A;  3TS4 A;  1AKL A;  3N2V A;  4FVL A;  3EHX A; 
#chains in the Genus database with same CATH homology
 4DPE A;  1GXD A;  1CAQ A;  3TVC A;  2V4B A;  1ZTQ A;  1BKC I;  4A7B A;  2ERQ A;  1BQQ M;  1MMR A;  1PWW A;  3KEJ A;  4WKI A;  1UMS A;  1L6J A;  3EWJ A;  1MMQ A;  3P1V A;  3KEC A;  2J0T A;  3GBO A;  1FM1 A;  4JPA A;  3G42 A;  1JK3 A;  1SLM A;  4L63 A;  2YUF A;  1YP1 A;  4ILW D;  1C7K A;  2MLS A;  3ELM A;  1BZS A;  456C A;  2K9C A;  3EDG A;  1BUV M;  1AF0 A;  4CTH A;  4Q1L A;  3B2Z A;  4H76 A;  1ZXV A;  2CLT A;  1R54 A;  1Y93 A;  1JAQ A;  4DD8 A;  2L0R A;  1AST A;  5CUH A;  5BOT A;  2OY4 A;  1QIA A;  3USN A;  2USN A;  5LAB A;  3LUM A;  2OY2 A;  4PKV A;  3MA2 A;  4FXY P;  1ATL A;  1BIW A;  3L0T A;  4ON1 A;  4PKU A;  3TSK A;  3LGP A;  5D2B A;  1H71 P;  2KRJ A;  1K7G A;  3ZXH A;  1OM6 A;  4GUY A;  3DTK A;  4XBH A;  4I35 A;  1XUR A;  1MNC A;  2DDY A;  1MMP A;  4GQL A;  4XM6 A;  4PKS A;  5D7W A;  2AIG P;  1IAA A;  1UEA A;  4IN9 A;  1JH1 A;  2OW2 A;  2W14 A;  4GF1 A;  1ZVX A;  1D8M A;  1XFX A;  1Z3J A;  1SU3 A;  4PKR A;  2E2D A;  1XFV A;  2X7M A;  4AYK A;  1CK7 A;  4H82 A;  4DV8 A;  4H3X A;  1YCM A;  3K7N A;  1FLS A;  5I4O A;  1JJ9 A;  3N2U A;  3KWV C;  1GKD A;  3WV2 A;  1I76 A;  4H30 A;  3LJT A;  1J7N A;  2OW9 A;  1QIB A;  2OXZ A;  1IAB A;  1JAN A;  830C A;  1IAC A;  2JSD A;  4XM8 A;  4L6T A;  1YQY A;  2RJQ A;  4FXQ A;  3OHL A;  5L79 A;  1KBC A;  2DDF A;  3U1R A;  2XS4 A;  2YIG A;  3LMC A;  3CKI A;  3HY9 A;  3LIK A;  3LK8 A;  3DPF A;  3DNG A;  1GE5 A;  1R1I A;  1PWP A;  4JA1 A;  1SLN A;  1FBL A;  4IJO A;  1GE6 A;  1SAT A;  4GWN A;  2I47 A;  3BA0 A;  5D1S A;  1ZP5 A;  3F1A A;  1KUK A;  4AIG A;  4A3W A;  1CIZ A;  4H49 A;  5D1T A;  1A86 A;  2MZE A;  1EB6 A;  1QJJ A;  3KME A;  3VTG A;  1XFZ A;  1KAP P;  3EDH A;  1Y8J A;  3KMC A;  3HDB A;  2OVZ A;  1PWQ A;  4XCT A;  1YOU A;  3DPE A;  2Z2D A;  3I7I A;  3LEA A;  1HOV A;  1XUC A;  2X3B A;  2W12 A;  2W13 A;  3DTI A;  2D1N A;  1QJI A;  5BOY A;  3HY7 A;  4GR3 A;  3RTT A;  3SHI A;  3F19 A;  2N8R A;  1B3D A;  1BUD A;  1KUF A;  2WO9 A;  5L7F A;  2K2G A;  3EDI A;  1USN A;  3I7G A;  2JIH A;  3DL1 A;  1JAP A;  1OMJ A;  1KUI A;  4IUW A;  2WO8 A;  1DMT A;  2DW2 A;  4JQG A;  1ROS A;  1KUH A;  3EHY A;  1EAK A;  2CKI A;  3LQ0 A;  2YB9 A;  2W0D A;  4GR8 A;  1R1J A;  1SMP A;  3OHO A;  5I0L A;  4DF9 A;  3HB2 P;  4PKQ A;  1CGE A;  2X3A A;  2FV5 A;  1JIW P;  1XFW A;  1IAG A;  1HTD A;  5I43 A;  2OXU A;  1Q3A A;  3RTS A;  2OI0 A;  1R1H A;  966C A;  4PKW A;  1DTH A;  1GO7 P;  3P24 A;  2POJ A;  4GWM A;  2MZI A;  1RM8 A;  3LJZ A;  1I1I P;  3F17 A;  3TT4 A;  4HX3 A;  1B8Y A;  2AYK A;  2SRT A;  1PWV A;  1HFC A;  4HMA A;  4FU4 A;  1OO9 A;  2Y6D A;  2RJP A;  2WOA A;  3DTE A;  1CGL A;  1CGF A;  4WKE A;  4GR0 A;  1XUD A;  3O64 A;  3F18 A;  2A8H A;  3AYU A;  3KEK A;  1R55 A;  4EFS A;  2JNP A;  5D1U A;  1BM6 A;  3B92 A;  5BPA A;  1AYK A;  1GKC A;  3HYG A;  2MLR A;  1G12 A;  1G4K A;  1RMZ A;  3LJG A;  1UTZ A;  1G49 A;  4H2E A;  1D7X A;  1S4B P;  1SRP A;  5B5O A;  1BSW A;  3LE9 A;  2Y6C A;  3B8Z A;  1HY7 A;  1ZS0 A;  4H1Q A;  1A85 A;  4G0D A;  3LKA A;  1OM7 A;  2ERP A;  3HBU P;  2DW1 A;  1KUG A;  1MMB A;  3KRY A;  4ZR5 A;  4J4M A;  5D3C A;  3DWB A;  1CQR A;  3LIL A;  3LIR A;  2OXW A;  2OW1 A;  1BQO A;  1XFU A;  1O0Q A;  3V96 B;  3Q2G A;  1K7Q A;  3F16 A;  1C8T A;  3LQB A;  3E8R A;  5I2Z A;  3HDA P;  1OM8 A;  1IAE A;  1D5J A;  1HV5 A;  1EUB A;  4H84 A;  2X3C A;  4WF6 A;  1BKC A;  4XM7 A;  5I12 A;  4WZV A;  2TCL A;  3KHI A;  5CZM A;  1CXV A;  1JIZ A;  1UMT A;  4G9L A;  3EDZ A;  1ND1 A;  2O36 A;  2QPJ A;  4PKT A;  1K7I A;  1OS2 A;  5CXA A;  4L7A A;  3ZUK A;  5H8X A;  1GE7 A;  4R3V A;  3O2X A;  1G05 A;  3WV1 A;  5I3M A;  3Q2H A;  2FV9 A;  3HBV P;  2DW0 A;  2MZH A;  3VI1 A;  3ZVS A;  2HU6 A;  3WV3 A;  1Y0V A;  1PWU A;  3LUN A;  2JT5 A;  1HFS A;  1XFY A;  1OS9 A;  2D1O A;  2OVX A;  1UTT A;  1WNI A;  2PJT A;  1O0T A;  1C3I A;  4JIJ A;  2OW0 A;  4L19 A;  1ZXC A;  4I03 A;  3K7L A;  1IAD A;  1QIC A;  2E3X A;  2OZR A;  1JAO A;  2XS3 A;  5JMY A;  2O3E A;  3AYK A;  4AUO A;  3DSL A;  1D8F A;  2ERO A;  3G5C A;  4AXQ A;  5B5P A;  1GO8 P;  3UVC A;  3F15 A;  3L0V A;  2JT6 A;  2J83 A;  4QKZ A;  1I73 A;  1G9K A;  1QUA A;  1BKC E;  1JKY A;  3NX7 A;  3AIG A;  4WK7 A;  4JP4 A;  2W15 A;  3TS4 A;  1AKL A;  3N2V A;  4FVL A;  3EHX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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