4GR3A

Crystal structure of the catalytic domain of human mmp12 in complex with selective phosphinic inhibitor rxp470a
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
159
structure length
159
Chain Sequence
MGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular determinants of a selective matrix metalloprotease-12 inhibitor: insights from crystallography and thermodynamic studies.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Macrophage metalloelastase
total genus 45
structure length 159
sequence length 159
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2012-08-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 4gr3A00
1KUKA 1EUBA 1CIZA 4WKEA 2JT5A 5CZMA 3LUMA 1JAQA 1BIWA 2A8HA 4DPEA 2JNPA 1MMRA 4FXQA 2WOAA 1D8FA 2E3XA 5I43A 3O64A 4GWNA 2AIGP 1JIZA 5L79A 1ZVXA 2J83A 3LJZA 2Y6CA 3L0TA 1GO7P 1BKCA 3SHIA 2MZIA 3N2UA 3LIKA 3WV1A 3HDBA 1PWPA 1JH1A 4A7BA 4L6TA 3I7IA 1HV5A 2QPJA 2X3BA 3OHOA 1OS9A 3LQ0A 3KEJA 1XFXA 4FXYP 3LGPA 4AXQA 2W15A 1ZTQA 1HFCA 2Z2DA 1C7KA 3L0VA 5BOYA 1JKYA 3P24A 1MMQA 3F17A 1EAKA 1B8YA 1BQQM 1D7XA 2TCLA 2OW2A 3TS4A 3VI1A 3Q2GA 5CXAA 4A3WA 1G9KA 3K7NA 2FV5A 2DW0A 1QJIA 4Q1LA 3EDZA 3AYUA 2J0TA 4IJOA 1JJ9A 1HTDA 2K9CA 3AYKA 2I47A 4H1QA 1DMTA 1CQRA 2N8RA 4WK7A 1G12A 1GE7A 1G05A 1H71P 1JANA 2AYKA 1G49A 1AF0A 1USNA 3EHXA 3EDGA 1GKDA 2ERQA 1ZP5A 4IUWA 1XUDA 1XFUA 1XUCA 2O3EA 2XS4A 1ZS0A 2MZEA 1O0QA 1K7GA 1ZXCA 3VTGA 1WNIA 2X7MA 1SRPA 3DPEA 4H3XA 1G4KA 1PWWA 2USNA 5H8XA 3E8RA 2XS3A 2DW2A 4PKVA 1C8TA 3ZXHA 4PKQA 3P1VA 4XM6A 1OO9A 1MMPA 4AIGA 1OM8A 1BSWA 3HBVP 4H82A 4DD8A 1QICA 5I4OA 1AKLA 1YOUA 2POJA 1IACA 1Y93A 2RJQA 5JMYA 1QJJA 2MZHA 4PKSA 1ND1A 4H84A 4H30A 1KUIA 4AUOA 1FM1A 2OZRA 1L6JA 1QIAA 3LMCA 1R1JA 1CXVA 3DNGA 3N2VA 1R55A 1YP1A 3G42A 4GF1A 1R1HA 2CLTA 2V4BA 4ILWD 3LJGA 1K7QA 3HB2P 2JT6A 3HY7A 4GR0A 1GKCA 1SLMA 1PWUA 3I7GA 1ZXVA 3HDAP 1XFVA 1A85A 2OI0A 456CA 3G5CA 1A86A 2SRTA 3BA0A 4XCTA 3ELMA 2KRJA 5BOTA 1DTHA 1OMJA 3KECA 1HOVA 2X3AA 5D2BA 4HX3A 5I0LA 1ROSA 1GXDA 1R1IA 2YIGA 2EROA 3LE9A 4GR3A 1JAPA 2OY4A 3F19A 4EFSA 1IABA 1IAEA 3B2ZA 1Z3JA 3HYGA 3AIGA 5D3CA 2YB9A 3WV3A 1IADA 4L19A 1SMPA 2JIHA 4R3VA 1I73A 3EWJA 1FLSA 2DDYA 1IAAA 2W12A 3DSLA 1OS2A 3GBOA 3LQBA 4WKIA 1XFWA 1AYKA 1JIWP 3EHYA 1PWQA 2OY2A 4DF9A 1Y0VA 4G0DA 3EDIA 4WF6A 1BQOA 5BPAA 1BKCI 2O36A 1BUVM 1D8MA 1UTTA 1MMBA 2OW1A 1GE5A 1CGLA 3WV2A 2OVZA 4XBHA 5LABA 2HU6A 4HMAA 5D7WA 1JAOA 1HFSA 1R54A 1KUHA 2RJPA 2WO8A 2W0DA 2DW1A 1C3IA 1CGFA 1Y8JA 1KAPP 2DDFA 4J4MA 4PKUA 4QKZA 3NX7A 4WZVA 4PKWA 3USNA 1BUDA 1XURA 2OW0A 1KUGA 5B5OA 2ERPA 3LEAA 1XFYA 3LUNA 2W13A 3F18A 3RTTA 3UVCA 2E2DA 3KRYA 3OHLA 3F1AA 4GR8A 1I1IP 1UTZA 1PWVA 2MLRA 1I76A 3KHIA 3F16A 3O2XA 3TSKA 3Q2HA 4H2EA 4CTHA 2JSDA 2OXZA 2K2GA 5L7FA 1K7IA 3EDHA 1ASTA 4GQLA 3TT4A 3KMCA 4L63A 4JIJA 1OM6A 1IAGA 3LJTA 1MNCA 2OVXA 5D1UA 1RM8A 3DL1A 4ON1A 1SATA 3TVCA 1O0TA 4PKRA 3DWBA 1J7NA 2OXUA 5D1SA 3KEKA 1BZSA 4DV8A 5I2ZA 1B3DA 1D5JA 2OXWA 2CKIA 3MA2A 3ZUKA 5I12A 4GWMA 4ZR5A 1EB6A 1KBCA 2X3CA 1XFZA 3CKIA 1UMSA 4I35A 4FVLA 1SLNA 3LK8A 3B8ZA 3V96B 4H76A 1YCMA 3ZVSA 3KMEA 2OW9A 1CGEA 1FBLA 4JPAA 1CK7A 2L0RA 4PKTA 3K7LA 3LIRA 1BM6A 1QIBA 2D1NA 1RMZA 4FU4A 1GE6A 2PJTA 5I3MA 4H49A 4GUYA 2MLSA 1UMTA 2FV9A 1S4BP 966CA 4G9LA 1GO8P 2Y6DA 1BKCE 1OM7A 1KUFA 1JK3A 1SU3A 3LKAA 4XM8A 5CUHA 3HY9A 1QUAA 3B92A 1CAQA 1ATLA 3U1RA 1Q3AA 3LILA 4IN9A 1YQYA 3KWVC 4JQGA 5D1TA 3RTSA 830CA 1HY7A 2W14A 2D1OA 1UEAA 4JA1A 3HBUP 4I03A 4JP4A 4XM7A 4AYKA 3DPFA 3F15A 2WO9A 5B5PA
chains in the Genus database with same CATH superfamily
1KUKA 1EUBA 1CIZA 4WKEA 2JT5A 5CZMA 3LUMA 1JAQA 1BIWA 2A8HA 4DPEA 2JNPA 1MMRA 4FXQA 2WOAA 1D8FA 2E3XA 5I43A 3O64A 4GWNA 2AIGP 1JIZA 5L79A 1ZVXA 2J83A 3LJZA 2Y6CA 3L0TA 1GO7P 1BKCA 3SHIA 2MZIA 3N2UA 3LIKA 3WV1A 3HDBA 1OZ9A 1PWPA 1JH1A 4A7BA 4L6TA 3I7IA 1HV5A 2QPJA 2X3BA 3OHOA 1OS9A 3LQ0A 3KEJA 1XFXA 4FXYP 3LGPA 4AXQA 2W15A 1ZTQA 1HFCA 2Z2DA 1C7KA 3L0VA 5BOYA 1JKYA 3P24A 1MMQA 3F17A 1EAKA 1B8YA 1BQQM 1D7XA 2TCLA 2OW2A 3TS4A 3VI1A 3Q2GA 5CXAA 4A3WA 1G9KA 3K7NA 2FV5A 2DW0A 1QJIA 4Q1LA 3EDZA 3AYUA 2J0TA 4IJOA 1JJ9A 1HTDA 2K9CA 3AYKA 2I47A 4H1QA 1DMTA 1CQRA 2N8RA 4WK7A 1G12A 1GE7A 1G05A 1H71P 1JANA 2AYKA 1G49A 1AF0A 1USNA 3EHXA 3EDGA 1GKDA 2ERQA 1ZP5A 4IUWA 1XUDA 1XFUA 1XUCA 2O3EA 2XS4A 1TVIA 1ZS0A 2MZEA 1O0QA 1K7GA 1ZXCA 3VTGA 1WNIA 2X7MA 1SRPA 3DPEA 4H3XA 1G4KA 1PWWA 2USNA 5H8XA 3E8RA 2XS3A 2DW2A 4PKVA 1C8TA 3ZXHA 4PKQA 3P1VA 4XM6A 3DTKA 1OO9A 1MMPA 4AIGA 1OM8A 1BSWA 3HBVP 4H82A 4DD8A 1QICA 5I4OA 1AKLA 1YOUA 2POJA 1IACA 1Y93A 2RJQA 5JMYA 1QJJA 2MZHA 4PKSA 1ND1A 4H84A 4H30A 1KUIA 4AUOA 1FM1A 2OZRA 1L6JA 1QIAA 3LMCA 1R1JA 1CXVA 3DNGA 3N2VA 1R55A 1YP1A 3G42A 4GF1A 1R1HA 2CLTA 2V4BA 4ILWD 3LJGA 1K7QA 3HB2P 2JT6A 3HY7A 4GR0A 1GKCA 1SLMA 1PWUA 3I7GA 1ZXVA 3HDAP 1XFVA 1A85A 2OI0A 456CA 3G5CA 1A86A 2SRTA 3BA0A 4XCTA 3ELMA 2KRJA 5BOTA 1DTHA 1OMJA 3KECA 1HOVA 2X3AA 5D2BA 4HX3A 5I0LA 1ROSA 1GXDA 1R1IA 2YIGA 2EROA 3LE9A 4GR3A 1JAPA 2OY4A 3F19A 4EFSA 1IABA 1IAEA 3B2ZA 1Z3JA 3HYGA 3AIGA 5D3CA 2YB9A 3WV3A 1IADA 4L19A 1SMPA 2JIHA 4R3VA 1I73A 3EWJA 1FLSA 2DDYA 1IAAA 2W12A 3DSLA 1OS2A 3GBOA 3LQBA 4WKIA 1XFWA 1AYKA 1JIWP 3EHYA 1PWQA 2OY2A 4DF9A 1Y0VA 4G0DA 3EDIA 4WF6A 1BQOA 5BPAA 1BKCI 2O36A 1BUVM 1D8MA 1UTTA 1MMBA 2OW1A 1GE5A 1CGLA 3WV2A 2OVZA 4XBHA 5LABA 2HU6A 4HMAA 5D7WA 1JAOA 1HFSA 1R54A 1KUHA 2RJPA 2WO8A 2W0DA 2DW1A 1C3IA 1CGFA 1Y8JA 1KAPP 2DDFA 4J4MA 4PKUA 4QKZA 3NX7A 4WZVA 4PKWA 3USNA 1BUDA 1XURA 2OW0A 1KUGA 5B5OA 2ERPA 3DTIA 3LEAA 1XFYA 3LUNA 2W13A 3F18A 3RTTA 3UVCA 2E2DA 3KRYA 3OHLA 3F1AA 4GR8A 1I1IP 1UTZA 1PWVA 2MLRA 1I76A 3KHIA 3F16A 3O2XA 3TSKA 3Q2HA 4H2EA 4CTHA 2JSDA 1XAXA 2OXZA 2K2GA 5L7FA 1K7IA 3EDHA 1ASTA 4GQLA 3TT4A 3KMCA 4L63A 4JIJA 1OM6A 1IAGA 3LJTA 1MNCA 2OVXA 5D1UA 1RM8A 3DL1A 4ON1A 1SATA 1XM5A 3TVCA 1O0TA 4PKRA 3DWBA 1J7NA 2OXUA 2YUFA 5D1SA 3KEKA 1BZSA 4DV8A 5I2ZA 1B3DA 1D5JA 2OXWA 2CKIA 3MA2A 3ZUKA 5I12A 4GWMA 4ZR5A 1EB6A 1KBCA 2X3CA 1XFZA 3CKIA 1UMSA 4I35A 4FVLA 1SLNA 3LK8A 3B8ZA 3V96B 4H76A 1YCMA 3ZVSA 3KMEA 2OW9A 1CGEA 1FBLA 4JPAA 1CK7A 2L0RA 4PKTA 3K7LA 3LIRA 1BM6A 1QIBA 2D1NA 1RMZA 4FU4A 1GE6A 2PJTA 5I3MA 4H49A 4GUYA 2MLSA 1UMTA 2FV9A 1S4BP 966CA 4L7AA 4G9LA 1GO8P 2Y6DA 1BKCE 1OM7A 1KUFA 1JK3A 1SU3A 3LKAA 4XM8A 5CUHA 3HY9A 1QUAA 3B92A 1CAQA 1ATLA 3U1RA 1Q3AA 3LILA 4IN9A 1YQYA 3DTEA 3KWVC 4JQGA 5D1TA 3RTSA 830CA 1HY7A 2W14A 2D1OA 1UEAA 4JA1A 3HBUP 4I03A 4JP4A 4XM7A 4AYKA 3DPFA 3F15A 2WO9A 5B5PA
chains in the Genus database with same CATH topology
1KUKA 1EUBA 1CIZA 4WKEA 2JT5A 5CZMA 3LUMA 1JAQA 1BIWA 2A8HA 4DPEA 2JNPA 1MMRA 4FXQA 2WOAA 1D8FA 2E3XA 5I43A 3O64A 4GWNA 2AIGP 1JIZA 5L79A 1ZVXA 2J83A 3LJZA 2Y6CA 3L0TA 1GO7P 1BKCA 3SHIA 2MZIA 3N2UA 3LIKA 3WV1A 3HDBA 1PWPA 1JH1A 4A7BA 4L6TA 3I7IA 1HV5A 2QPJA 2X3BA 3OHOA 1OS9A 3LQ0A 3KEJA 1XFXA 4FXYP 3LGPA 4AXQA 2W15A 1ZTQA 1HFCA 2Z2DA 1C7KA 3L0VA 5BOYA 1JKYA 3P24A 1MMQA 3F17A 1EAKA 1B8YA 1BQQM 1D7XA 2TCLA 2OW2A 3TS4A 3VI1A 3Q2GA 5CXAA 4A3WA 1G9KA 3K7NA 2FV5A 2DW0A 1QJIA 4Q1LA 3EDZA 3AYUA 2J0TA 4IJOA 1JJ9A 1HTDA 2K9CA 3AYKA 2I47A 4H1QA 1DMTA 1CQRA 2N8RA 4WK7A 1G12A 1GE7A 1G05A 1H71P 1JANA 2AYKA 1G49A 1AF0A 1USNA 3EHXA 3EDGA 1GKDA 2ERQA 1ZP5A 4IUWA 1XUDA 1XFUA 1XUCA 2O3EA 2XS4A 1ZS0A 2MZEA 1O0QA 1K7GA 1ZXCA 3VTGA 1WNIA 2X7MA 1SRPA 3DPEA 4H3XA 1G4KA 1PWWA 2USNA 5H8XA 3E8RA 2XS3A 2DW2A 4PKVA 1C8TA 3ZXHA 4PKQA 3P1VA 4XM6A 3DTKA 1OO9A 1MMPA 4AIGA 1OM8A 1BSWA 3HBVP 4H82A 4DD8A 1QICA 5I4OA 1AKLA 1YOUA 2POJA 1IACA 1Y93A 2RJQA 5JMYA 1QJJA 2MZHA 4PKSA 1ND1A 4H84A 4H30A 1KUIA 4AUOA 1FM1A 2OZRA 1L6JA 1QIAA 3LMCA 1R1JA 1CXVA 3DNGA 3N2VA 1R55A 1YP1A 3G42A 4GF1A 1R1HA 2CLTA 2V4BA 4ILWD 3LJGA 1K7QA 3HB2P 2JT6A 3HY7A 4GR0A 1GKCA 1SLMA 1PWUA 3I7GA 1ZXVA 3HDAP 1XFVA 1A85A 2OI0A 456CA 3G5CA 1A86A 2SRTA 3BA0A 4XCTA 3ELMA 2KRJA 5BOTA 1DTHA 1OMJA 3KECA 1HOVA 2X3AA 5D2BA 4HX3A 5I0LA 1ROSA 1GXDA 1R1IA 2YIGA 2EROA 3LE9A 4GR3A 1JAPA 2OY4A 3F19A 4EFSA 1IABA 1IAEA 3B2ZA 1Z3JA 3HYGA 3AIGA 5D3CA 2YB9A 3WV3A 1IADA 4L19A 1SMPA 2JIHA 4R3VA 1I73A 3EWJA 1FLSA 2DDYA 1IAAA 2W12A 3DSLA 1OS2A 3GBOA 3LQBA 4WKIA 1XFWA 1AYKA 1JIWP 3EHYA 1PWQA 2OY2A 4DF9A 1Y0VA 4G0DA 3EDIA 4WF6A 1BQOA 5BPAA 1BKCI 2O36A 1BUVM 1D8MA 1UTTA 1MMBA 2OW1A 1GE5A 1CGLA 3WV2A 2OVZA 4XBHA 5LABA 2HU6A 4HMAA 5D7WA 1JAOA 1HFSA 1R54A 1KUHA 2RJPA 2WO8A 2W0DA 2DW1A 1C3IA 1CGFA 1Y8JA 1KAPP 2DDFA 4J4MA 4PKUA 4QKZA 3NX7A 4WZVA 4PKWA 3USNA 1BUDA 1XURA 2OW0A 1KUGA 5B5OA 2ERPA 3DTIA 3LEAA 1XFYA 3LUNA 2W13A 3F18A 3RTTA 3UVCA 2E2DA 3KRYA 3OHLA 3F1AA 4GR8A 1I1IP 1UTZA 1PWVA 2MLRA 1I76A 3KHIA 3F16A 3O2XA 3TSKA 3Q2HA 4H2EA 4CTHA 2JSDA 2OXZA 2K2GA 5L7FA 1K7IA 3EDHA 1ASTA 4GQLA 3TT4A 3KMCA 4L63A 4JIJA 1OM6A 1IAGA 3LJTA 1MNCA 2OVXA 5D1UA 1RM8A 3DL1A 4ON1A 1SATA 3TVCA 1O0TA 4PKRA 3DWBA 1J7NA 2OXUA 2YUFA 5D1SA 3KEKA 1BZSA 4DV8A 5I2ZA 1B3DA 1D5JA 2OXWA 2CKIA 3MA2A 3ZUKA 5I12A 4GWMA 4ZR5A 1EB6A 1KBCA 2X3CA 1XFZA 3CKIA 1UMSA 4I35A 4FVLA 1SLNA 3LK8A 3B8ZA 3V96B 4H76A 1YCMA 3ZVSA 3KMEA 2OW9A 1CGEA 1FBLA 4JPAA 1CK7A 2L0RA 4PKTA 3K7LA 3LIRA 1BM6A 1QIBA 2D1NA 1RMZA 4FU4A 1GE6A 2PJTA 5I3MA 4H49A 4GUYA 2MLSA 1UMTA 2FV9A 1S4BP 966CA 4L7AA 4G9LA 1GO8P 2Y6DA 1BKCE 1OM7A 1KUFA 1JK3A 1SU3A 3LKAA 4XM8A 5CUHA 3HY9A 1QUAA 3B92A 1CAQA 1ATLA 3U1RA 1Q3AA 3LILA 4IN9A 1YQYA 3DTEA 3KWVC 4JQGA 5D1TA 3RTSA 830CA 1HY7A 2W14A 2D1OA 1UEAA 4JA1A 3HBUP 4I03A 4JP4A 4XM7A 4AYKA 3DPFA 3F15A 2WO9A 5B5PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KUK A;  1EUB A;  1CIZ A;  4WKE A;  2JT5 A;  5CZM A;  3LUM A;  1JAQ A;  1BIW A;  2A8H A;  4DPE A;  2JNP A;  1MMR A;  4FXQ A;  2WOA A;  1D8F A;  2E3X A;  5I43 A;  3O64 A;  4GWN A;  2AIG P;  1JIZ A;  5L79 A;  1ZVX A;  2J83 A;  3LJZ A;  2Y6C A;  3L0T A;  1GO7 P;  1BKC A;  3SHI A;  2MZI A;  3N2U A;  3LIK A;  3WV1 A;  3HDB A;  1PWP A;  1JH1 A;  4A7B A;  4L6T A;  3I7I A;  1HV5 A;  2QPJ A;  2X3B A;  3OHO A;  1OS9 A;  3LQ0 A;  3KEJ A;  1XFX A;  4FXY P;  3LGP A;  4AXQ A;  2W15 A;  1ZTQ A;  1HFC A;  2Z2D A;  1C7K A;  3L0V A;  5BOY A;  1JKY A;  3P24 A;  1MMQ A;  3F17 A;  1EAK A;  1B8Y A;  1BQQ M;  1D7X A;  2TCL A;  2OW2 A;  3TS4 A;  3VI1 A;  3Q2G A;  5CXA A;  4A3W A;  1G9K A;  3K7N A;  2FV5 A;  2DW0 A;  1QJI A;  4Q1L A;  3EDZ A;  3AYU A;  2J0T A;  4IJO A;  1JJ9 A;  1HTD A;  2K9C A;  3AYK A;  2I47 A;  4H1Q A;  1DMT A;  1CQR A;  2N8R A;  4WK7 A;  1G12 A;  1GE7 A;  1G05 A;  1H71 P;  1JAN A;  2AYK A;  1G49 A;  1AF0 A;  1USN A;  3EHX A;  3EDG A;  1GKD A;  2ERQ A;  1ZP5 A;  4IUW A;  1XUD A;  1XFU A;  1XUC A;  2O3E A;  2XS4 A;  1ZS0 A;  2MZE A;  1O0Q A;  1K7G A;  1ZXC A;  3VTG A;  1WNI A;  2X7M A;  1SRP A;  3DPE A;  4H3X A;  1G4K A;  1PWW A;  2USN A;  5H8X A;  3E8R A;  2XS3 A;  2DW2 A;  4PKV A;  1C8T A;  3ZXH A;  4PKQ A;  3P1V A;  4XM6 A;  1OO9 A;  1MMP A;  4AIG A;  1OM8 A;  1BSW A;  3HBV P;  4H82 A;  4DD8 A;  1QIC A;  5I4O A;  1AKL A;  1YOU A;  2POJ A;  1IAC A;  1Y93 A;  2RJQ A;  5JMY A;  1QJJ A;  2MZH A;  4PKS A;  1ND1 A;  4H84 A;  4H30 A;  1KUI A;  4AUO A;  1FM1 A;  2OZR A;  1L6J A;  1QIA A;  3LMC A;  1R1J A;  1CXV A;  3DNG A;  3N2V A;  1R55 A;  1YP1 A;  3G42 A;  4GF1 A;  1R1H A;  2CLT A;  2V4B A;  4ILW D;  3LJG A;  1K7Q A;  3HB2 P;  2JT6 A;  3HY7 A;  4GR0 A;  1GKC A;  1SLM A;  1PWU A;  3I7G A;  1ZXV A;  3HDA P;  1XFV A;  1A85 A;  2OI0 A;  456C A;  3G5C A;  1A86 A;  2SRT A;  3BA0 A;  4XCT A;  3ELM A;  2KRJ A;  5BOT A;  1DTH A;  1OMJ A;  3KEC A;  1HOV A;  2X3A A;  5D2B A;  4HX3 A;  5I0L A;  1ROS A;  1GXD A;  1R1I A;  2YIG A;  2ERO A;  3LE9 A;  4GR3 A;  1JAP A;  2OY4 A;  3F19 A;  4EFS A;  1IAB A;  1IAE A;  3B2Z A;  1Z3J A;  3HYG A;  3AIG A;  5D3C A;  2YB9 A;  3WV3 A;  1IAD A;  4L19 A;  1SMP A;  2JIH A;  4R3V A;  1I73 A;  3EWJ A;  1FLS A;  2DDY A;  1IAA A;  2W12 A;  3DSL A;  1OS2 A;  3GBO A;  3LQB A;  4WKI A;  1XFW A;  1AYK A;  1JIW P;  3EHY A;  1PWQ A;  2OY2 A;  4DF9 A;  1Y0V A;  4G0D A;  3EDI A;  4WF6 A;  1BQO A;  5BPA A;  1BKC I;  2O36 A;  1BUV M;  1D8M A;  1UTT A;  1MMB A;  2OW1 A;  1GE5 A;  1CGL A;  3WV2 A;  2OVZ A;  4XBH A;  5LAB A;  2HU6 A;  4HMA A;  5D7W A;  1JAO A;  1HFS A;  1R54 A;  1KUH A;  2RJP A;  2WO8 A;  2W0D A;  2DW1 A;  1C3I A;  1CGF A;  1Y8J A;  1KAP P;  2DDF A;  4J4M A;  4PKU A;  4QKZ A;  3NX7 A;  4WZV A;  4PKW A;  3USN A;  1BUD A;  1XUR A;  2OW0 A;  1KUG A;  5B5O A;  2ERP A;  3LEA A;  1XFY A;  3LUN A;  2W13 A;  3F18 A;  3RTT A;  3UVC A;  2E2D A;  3KRY A;  3OHL A;  3F1A A;  4GR8 A;  1I1I P;  1UTZ A;  1PWV A;  2MLR A;  1I76 A;  3KHI A;  3F16 A;  3O2X A;  3TSK A;  3Q2H A;  4H2E A;  4CTH A;  2JSD A;  2OXZ A;  2K2G A;  5L7F A;  1K7I A;  3EDH A;  1AST A;  4GQL A;  3TT4 A;  3KMC A;  4L63 A;  4JIJ A;  1OM6 A;  1IAG A;  3LJT A;  1MNC A;  2OVX A;  5D1U A;  1RM8 A;  3DL1 A;  4ON1 A;  1SAT A;  3TVC A;  1O0T A;  4PKR A;  3DWB A;  1J7N A;  2OXU A;  5D1S A;  3KEK A;  1BZS A;  4DV8 A;  5I2Z A;  1B3D A;  1D5J A;  2OXW A;  2CKI A;  3MA2 A;  3ZUK A;  5I12 A;  4GWM A;  4ZR5 A;  1EB6 A;  1KBC A;  2X3C A;  1XFZ A;  3CKI A;  1UMS A;  4I35 A;  4FVL A;  1SLN A;  3LK8 A;  3B8Z A;  3V96 B;  4H76 A;  1YCM A;  3ZVS A;  3KME A;  2OW9 A;  1CGE A;  1FBL A;  4JPA A;  1CK7 A;  2L0R A;  4PKT A;  3K7L A;  3LIR A;  1BM6 A;  1QIB A;  2D1N A;  1RMZ A;  4FU4 A;  1GE6 A;  2PJT A;  5I3M A;  4H49 A;  4GUY A;  2MLS A;  1UMT A;  2FV9 A;  1S4B P;  966C A;  4G9L A;  1GO8 P;  2Y6D A;  1BKC E;  1OM7 A;  1KUF A;  1JK3 A;  1SU3 A;  3LKA A;  4XM8 A;  5CUH A;  3HY9 A;  1QUA A;  3B92 A;  1CAQ A;  1ATL A;  3U1R A;  1Q3A A;  3LIL A;  4IN9 A;  1YQY A;  3KWV C;  4JQG A;  5D1T A;  3RTS A;  830C A;  1HY7 A;  2W14 A;  2D1O A;  1UEA A;  4JA1 A;  3HBU P;  4I03 A;  4JP4 A;  4XM7 A;  4AYK A;  3DPF A;  3F15 A;  2WO9 A;  5B5P A; 
#chains in the Genus database with same CATH topology
 1KUK A;  1EUB A;  1CIZ A;  4WKE A;  2JT5 A;  5CZM A;  3LUM A;  1JAQ A;  1BIW A;  2A8H A;  4DPE A;  2JNP A;  1MMR A;  4FXQ A;  2WOA A;  1D8F A;  2E3X A;  5I43 A;  3O64 A;  4GWN A;  2AIG P;  1JIZ A;  5L79 A;  1ZVX A;  2J83 A;  3LJZ A;  2Y6C A;  3L0T A;  1GO7 P;  1BKC A;  3SHI A;  2MZI A;  3N2U A;  3LIK A;  3WV1 A;  3HDB A;  1OZ9 A;  1PWP A;  1JH1 A;  4A7B A;  4L6T A;  3I7I A;  1HV5 A;  2QPJ A;  2X3B A;  3OHO A;  1OS9 A;  3LQ0 A;  3KEJ A;  1XFX A;  4FXY P;  3LGP A;  4AXQ A;  2W15 A;  1ZTQ A;  1HFC A;  2Z2D A;  1C7K A;  3L0V A;  5BOY A;  1JKY A;  3P24 A;  1MMQ A;  3F17 A;  1EAK A;  1B8Y A;  1BQQ M;  1D7X A;  2TCL A;  2OW2 A;  3TS4 A;  3VI1 A;  3Q2G A;  5CXA A;  4A3W A;  1G9K A;  3K7N A;  2FV5 A;  2DW0 A;  1QJI A;  4Q1L A;  3EDZ A;  3AYU A;  2J0T A;  4IJO A;  1JJ9 A;  1HTD A;  2K9C A;  3AYK A;  2I47 A;  4H1Q A;  1DMT A;  1CQR A;  2N8R A;  4WK7 A;  1G12 A;  1GE7 A;  1G05 A;  1H71 P;  1JAN A;  2AYK A;  1G49 A;  1AF0 A;  1USN A;  3EHX A;  3EDG A;  1GKD A;  2ERQ A;  1ZP5 A;  4IUW A;  1XUD A;  1XFU A;  1XUC A;  2O3E A;  2XS4 A;  1TVI A;  1ZS0 A;  2MZE A;  1O0Q A;  1K7G A;  1ZXC A;  3VTG A;  1WNI A;  2X7M A;  1SRP A;  3DPE A;  4H3X A;  1G4K A;  1PWW A;  2USN A;  5H8X A;  3E8R A;  2XS3 A;  2DW2 A;  4PKV A;  1C8T A;  3ZXH A;  4PKQ A;  3P1V A;  4XM6 A;  3DTK A;  1OO9 A;  1MMP A;  4AIG A;  1OM8 A;  1BSW A;  3HBV P;  4H82 A;  4DD8 A;  1QIC A;  5I4O A;  1AKL A;  1YOU A;  2POJ A;  1IAC A;  1Y93 A;  2RJQ A;  5JMY A;  1QJJ A;  2MZH A;  4PKS A;  1ND1 A;  4H84 A;  4H30 A;  1KUI A;  4AUO A;  1FM1 A;  2OZR A;  1L6J A;  1QIA A;  3LMC A;  1R1J A;  1CXV A;  3DNG A;  3N2V A;  1R55 A;  1YP1 A;  3G42 A;  4GF1 A;  1R1H A;  2CLT A;  2V4B A;  4ILW D;  3LJG A;  1K7Q A;  3HB2 P;  2JT6 A;  3HY7 A;  4GR0 A;  1GKC A;  1SLM A;  1PWU A;  3I7G A;  1ZXV A;  3HDA P;  1XFV A;  1A85 A;  2OI0 A;  456C A;  3G5C A;  1A86 A;  2SRT A;  3BA0 A;  4XCT A;  3ELM A;  2KRJ A;  5BOT A;  1DTH A;  1OMJ A;  3KEC A;  1HOV A;  2X3A A;  5D2B A;  4HX3 A;  5I0L A;  1ROS A;  1GXD A;  1R1I A;  2YIG A;  2ERO A;  3LE9 A;  4GR3 A;  1JAP A;  2OY4 A;  3F19 A;  4EFS A;  1IAB A;  1IAE A;  3B2Z A;  1Z3J A;  3HYG A;  3AIG A;  5D3C A;  2YB9 A;  3WV3 A;  1IAD A;  4L19 A;  1SMP A;  2JIH A;  4R3V A;  1I73 A;  3EWJ A;  1FLS A;  2DDY A;  1IAA A;  2W12 A;  3DSL A;  1OS2 A;  3GBO A;  3LQB A;  4WKI A;  1XFW A;  1AYK A;  1JIW P;  3EHY A;  1PWQ A;  2OY2 A;  4DF9 A;  1Y0V A;  4G0D A;  3EDI A;  4WF6 A;  1BQO A;  5BPA A;  1BKC I;  2O36 A;  1BUV M;  1D8M A;  1UTT A;  1MMB A;  2OW1 A;  1GE5 A;  1CGL A;  3WV2 A;  2OVZ A;  4XBH A;  5LAB A;  2HU6 A;  4HMA A;  5D7W A;  1JAO A;  1HFS A;  1R54 A;  1KUH A;  2RJP A;  2WO8 A;  2W0D A;  2DW1 A;  1C3I A;  1CGF A;  1Y8J A;  1KAP P;  2DDF A;  4J4M A;  4PKU A;  4QKZ A;  3NX7 A;  4WZV A;  4PKW A;  3USN A;  1BUD A;  1XUR A;  2OW0 A;  1KUG A;  5B5O A;  2ERP A;  3DTI A;  3LEA A;  1XFY A;  3LUN A;  2W13 A;  3F18 A;  3RTT A;  3UVC A;  2E2D A;  3KRY A;  3OHL A;  3F1A A;  4GR8 A;  1I1I P;  1UTZ A;  1PWV A;  2MLR A;  1I76 A;  3KHI A;  3F16 A;  3O2X A;  3TSK A;  3Q2H A;  4H2E A;  4CTH A;  2JSD A;  1XAX A;  2OXZ A;  2K2G A;  5L7F A;  1K7I A;  3EDH A;  1AST A;  4GQL A;  3TT4 A;  3KMC A;  4L63 A;  4JIJ A;  1OM6 A;  1IAG A;  3LJT A;  1MNC A;  2OVX A;  5D1U A;  1RM8 A;  3DL1 A;  4ON1 A;  1SAT A;  1XM5 A;  3TVC A;  1O0T A;  4PKR A;  3DWB A;  1J7N A;  2OXU A;  2YUF A;  5D1S A;  3KEK A;  1BZS A;  4DV8 A;  5I2Z A;  1B3D A;  1D5J A;  2OXW A;  2CKI A;  3MA2 A;  3ZUK A;  5I12 A;  4GWM A;  4ZR5 A;  1EB6 A;  1KBC A;  2X3C A;  1XFZ A;  3CKI A;  1UMS A;  4I35 A;  4FVL A;  1SLN A;  3LK8 A;  3B8Z A;  3V96 B;  4H76 A;  1YCM A;  3ZVS A;  3KME A;  2OW9 A;  1CGE A;  1FBL A;  4JPA A;  1CK7 A;  2L0R A;  4PKT A;  3K7L A;  3LIR A;  1BM6 A;  1QIB A;  2D1N A;  1RMZ A;  4FU4 A;  1GE6 A;  2PJT A;  5I3M A;  4H49 A;  4GUY A;  2MLS A;  1UMT A;  2FV9 A;  1S4B P;  966C A;  4L7A A;  4G9L A;  1GO8 P;  2Y6D A;  1BKC E;  1OM7 A;  1KUF A;  1JK3 A;  1SU3 A;  3LKA A;  4XM8 A;  5CUH A;  3HY9 A;  1QUA A;  3B92 A;  1CAQ A;  1ATL A;  3U1R A;  1Q3A A;  3LIL A;  4IN9 A;  1YQY A;  3DTE A;  3KWV C;  4JQG A;  5D1T A;  3RTS A;  830C A;  1HY7 A;  2W14 A;  2D1O A;  1UEA A;  4JA1 A;  3HBU P;  4I03 A;  4JP4 A;  4XM7 A;  4AYK A;  3DPF A;  3F15 A;  2WO9 A;  5B5P A; 
#chains in the Genus database with same CATH homology
 1KUK A;  1EUB A;  1CIZ A;  4WKE A;  2JT5 A;  5CZM A;  3LUM A;  1JAQ A;  1BIW A;  2A8H A;  4DPE A;  2JNP A;  1MMR A;  4FXQ A;  2WOA A;  1D8F A;  2E3X A;  5I43 A;  3O64 A;  4GWN A;  2AIG P;  1JIZ A;  5L79 A;  1ZVX A;  2J83 A;  3LJZ A;  2Y6C A;  3L0T A;  1GO7 P;  1BKC A;  3SHI A;  2MZI A;  3N2U A;  3LIK A;  3WV1 A;  3HDB A;  1PWP A;  1JH1 A;  4A7B A;  4L6T A;  3I7I A;  1HV5 A;  2QPJ A;  2X3B A;  3OHO A;  1OS9 A;  3LQ0 A;  3KEJ A;  1XFX A;  4FXY P;  3LGP A;  4AXQ A;  2W15 A;  1ZTQ A;  1HFC A;  2Z2D A;  1C7K A;  3L0V A;  5BOY A;  1JKY A;  3P24 A;  1MMQ A;  3F17 A;  1EAK A;  1B8Y A;  1BQQ M;  1D7X A;  2TCL A;  2OW2 A;  3TS4 A;  3VI1 A;  3Q2G A;  5CXA A;  4A3W A;  1G9K A;  3K7N A;  2FV5 A;  2DW0 A;  1QJI A;  4Q1L A;  3EDZ A;  3AYU A;  2J0T A;  4IJO A;  1JJ9 A;  1HTD A;  2K9C A;  3AYK A;  2I47 A;  4H1Q A;  1DMT A;  1CQR A;  2N8R A;  4WK7 A;  1G12 A;  1GE7 A;  1G05 A;  1H71 P;  1JAN A;  2AYK A;  1G49 A;  1AF0 A;  1USN A;  3EHX A;  3EDG A;  1GKD A;  2ERQ A;  1ZP5 A;  4IUW A;  1XUD A;  1XFU A;  1XUC A;  2O3E A;  2XS4 A;  1ZS0 A;  2MZE A;  1O0Q A;  1K7G A;  1ZXC A;  3VTG A;  1WNI A;  2X7M A;  1SRP A;  3DPE A;  4H3X A;  1G4K A;  1PWW A;  2USN A;  5H8X A;  3E8R A;  2XS3 A;  2DW2 A;  4PKV A;  1C8T A;  3ZXH A;  4PKQ A;  3P1V A;  4XM6 A;  3DTK A;  1OO9 A;  1MMP A;  4AIG A;  1OM8 A;  1BSW A;  3HBV P;  4H82 A;  4DD8 A;  1QIC A;  5I4O A;  1AKL A;  1YOU A;  2POJ A;  1IAC A;  1Y93 A;  2RJQ A;  5JMY A;  1QJJ A;  2MZH A;  4PKS A;  1ND1 A;  4H84 A;  4H30 A;  1KUI A;  4AUO A;  1FM1 A;  2OZR A;  1L6J A;  1QIA A;  3LMC A;  1R1J A;  1CXV A;  3DNG A;  3N2V A;  1R55 A;  1YP1 A;  3G42 A;  4GF1 A;  1R1H A;  2CLT A;  2V4B A;  4ILW D;  3LJG A;  1K7Q A;  3HB2 P;  2JT6 A;  3HY7 A;  4GR0 A;  1GKC A;  1SLM A;  1PWU A;  3I7G A;  1ZXV A;  3HDA P;  1XFV A;  1A85 A;  2OI0 A;  456C A;  3G5C A;  1A86 A;  2SRT A;  3BA0 A;  4XCT A;  3ELM A;  2KRJ A;  5BOT A;  1DTH A;  1OMJ A;  3KEC A;  1HOV A;  2X3A A;  5D2B A;  4HX3 A;  5I0L A;  1ROS A;  1GXD A;  1R1I A;  2YIG A;  2ERO A;  3LE9 A;  4GR3 A;  1JAP A;  2OY4 A;  3F19 A;  4EFS A;  1IAB A;  1IAE A;  3B2Z A;  1Z3J A;  3HYG A;  3AIG A;  5D3C A;  2YB9 A;  3WV3 A;  1IAD A;  4L19 A;  1SMP A;  2JIH A;  4R3V A;  1I73 A;  3EWJ A;  1FLS A;  2DDY A;  1IAA A;  2W12 A;  3DSL A;  1OS2 A;  3GBO A;  3LQB A;  4WKI A;  1XFW A;  1AYK A;  1JIW P;  3EHY A;  1PWQ A;  2OY2 A;  4DF9 A;  1Y0V A;  4G0D A;  3EDI A;  4WF6 A;  1BQO A;  5BPA A;  1BKC I;  2O36 A;  1BUV M;  1D8M A;  1UTT A;  1MMB A;  2OW1 A;  1GE5 A;  1CGL A;  3WV2 A;  2OVZ A;  4XBH A;  5LAB A;  2HU6 A;  4HMA A;  5D7W A;  1JAO A;  1HFS A;  1R54 A;  1KUH A;  2RJP A;  2WO8 A;  2W0D A;  2DW1 A;  1C3I A;  1CGF A;  1Y8J A;  1KAP P;  2DDF A;  4J4M A;  4PKU A;  4QKZ A;  3NX7 A;  4WZV A;  4PKW A;  3USN A;  1BUD A;  1XUR A;  2OW0 A;  1KUG A;  5B5O A;  2ERP A;  3DTI A;  3LEA A;  1XFY A;  3LUN A;  2W13 A;  3F18 A;  3RTT A;  3UVC A;  2E2D A;  3KRY A;  3OHL A;  3F1A A;  4GR8 A;  1I1I P;  1UTZ A;  1PWV A;  2MLR A;  1I76 A;  3KHI A;  3F16 A;  3O2X A;  3TSK A;  3Q2H A;  4H2E A;  4CTH A;  2JSD A;  2OXZ A;  2K2G A;  5L7F A;  1K7I A;  3EDH A;  1AST A;  4GQL A;  3TT4 A;  3KMC A;  4L63 A;  4JIJ A;  1OM6 A;  1IAG A;  3LJT A;  1MNC A;  2OVX A;  5D1U A;  1RM8 A;  3DL1 A;  4ON1 A;  1SAT A;  3TVC A;  1O0T A;  4PKR A;  3DWB A;  1J7N A;  2OXU A;  2YUF A;  5D1S A;  3KEK A;  1BZS A;  4DV8 A;  5I2Z A;  1B3D A;  1D5J A;  2OXW A;  2CKI A;  3MA2 A;  3ZUK A;  5I12 A;  4GWM A;  4ZR5 A;  1EB6 A;  1KBC A;  2X3C A;  1XFZ A;  3CKI A;  1UMS A;  4I35 A;  4FVL A;  1SLN A;  3LK8 A;  3B8Z A;  3V96 B;  4H76 A;  1YCM A;  3ZVS A;  3KME A;  2OW9 A;  1CGE A;  1FBL A;  4JPA A;  1CK7 A;  2L0R A;  4PKT A;  3K7L A;  3LIR A;  1BM6 A;  1QIB A;  2D1N A;  1RMZ A;  4FU4 A;  1GE6 A;  2PJT A;  5I3M A;  4H49 A;  4GUY A;  2MLS A;  1UMT A;  2FV9 A;  1S4B P;  966C A;  4L7A A;  4G9L A;  1GO8 P;  2Y6D A;  1BKC E;  1OM7 A;  1KUF A;  1JK3 A;  1SU3 A;  3LKA A;  4XM8 A;  5CUH A;  3HY9 A;  1QUA A;  3B92 A;  1CAQ A;  1ATL A;  3U1R A;  1Q3A A;  3LIL A;  4IN9 A;  1YQY A;  3DTE A;  3KWV C;  4JQG A;  5D1T A;  3RTS A;  830C A;  1HY7 A;  2W14 A;  2D1O A;  1UEA A;  4JA1 A;  3HBU P;  4I03 A;  4JP4 A;  4XM7 A;  4AYK A;  3DPF A;  3F15 A;  2WO9 A;  5B5P A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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