4GR8A

Crystal structure of the catalytic domain of human mmp12 in complex with selective phosphinic inhibitor rxp470c
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
152
structure length
152
Chain Sequence
KHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
publication title Molecular determinants of a selective matrix metalloprotease-12 inhibitor: insights from crystallography and thermodynamic studies.
pubmed doi rcsb
molecule keywords Macrophage metalloelastase
total genus 44
structure length 152
sequence length 152
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2012-08-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 4gr8A00
1XUDA 3DL1A 4A7BA 1IAGA 3DWBA 1SATA 1OM7A 1MMPA 1G49A 1A86A 3ZUKA 1SLMA 3I7GA 1OM6A 4H30A 1ROSA 1QUAA 4QKZA 2OXUA 3NX7A 3B92A 3HBUP 1BQQM 1BUDA 1XFZA 1BIWA 4PKQA 1CIZA 2ERQA 5L7FA 3ZXHA 4FXYP 1JK3A 1OS2A 5JMYA 1SU3A 1BQOA 3Q2GA 1R55A 1KAPP 2HU6A 5D1TA 1XFVA 2W12A 3N2VA 5BOTA 5CZMA 1ZS0A 3TVCA 5CUHA 1PWUA 3HY7A 4FXQA 1FBLA 1PWWA 3LQ0A 4PKUA 1USNA 1OO9A 1Q3AA 1QIBA 3P1VA 3KHIA 1KUFA 4L63A 2RJPA 4GUYA 4IJOA 1XFXA 1D5JA 2XS3A 4GF1A 1QJJA 4A3WA 3HDAP 1A85A 3OHOA 4ON1A 1BM6A 2L0RA 2E2DA 1AYKA 2OZRA 3L0TA 1C7KA 1ASTA 3DPFA 3LKAA 2CKIA 4IN9A 2JT5A 2OVXA 3BA0A 3F17A 4I03A 1BKCE 1IABA 4GWMA 2USNA 1PWPA 3ELMA 2DDYA 1C8TA 3HDBA 1G05A 4R3VA 3VI1A 3UVCA 2MZHA 4WKEA 1XFYA 3TS4A 3EDZA 5LABA 1KUGA 1EB6A 5B5PA 3P24A 2MZIA 1R1JA 1JAOA 2MLSA 1H71P 3WV2A 4DV8A 1UMTA 2OW0A 3U1RA 1HOVA 1O0TA 2MLRA 3EDHA 1YOUA 4GR0A 830CA 5D1UA 1IAEA 1QICA 1R54A 2YB9A 4JIJA 1R1HA 1FM1A 5D3CA 3K7LA 3HY9A 2Y6CA 5BPAA 5I43A 4PKVA 1CGLA 3WV3A 3Q2HA 1BUVM 2O3EA 3TSKA 1KUKA 1R1IA 5I12A 1FLSA 1GKDA 4GQLA 1CK7A 2KRJA 3WV1A 4DF9A 4WF6A 1AKLA 1IADA 2O36A 5H8XA 2A8HA 1Z3JA 2RJQA 2SRTA 2W15A 1PWQA 3LJTA 4Q1LA 1Y0VA 1EAKA 1UTZA 2POJA 4AXQA 3OHLA 2W14A 1RM8A 5BOYA 3V96B 2J83A 3E8RA 4JQGA 1UMSA 1DTHA 2QPJA 966CA 4XM8A 4WK7A 4JPAA 4XM7A 2OVZA 4XM6A 2DW1A 2X3CA 456CA 5I2ZA 1ZXVA 4XCTA 2OXZA 2FV9A 2E3XA 3G5CA 1YP1A 3LEAA 4FVLA 3LJZA 3EDGA 1QIAA 3DPEA 4GR8A 1D8MA 3RTSA 2W0DA 1BKCA 1D8FA 1BKCI 4G9LA 1ZP5A 4DPEA 5B5OA 3LQBA 1EUBA 1AF0A 3O2XA 4H49A 2JSDA 1IACA 1KUIA 3GBOA 1K7QA 1ZVXA 2OI0A 2Z2DA 3LILA 1L6JA 2N8RA 1RMZA 3TT4A 1UTTA 2WO8A 3KMCA 1ATLA 3LIKA 1K7IA 2J0TA 2EROA 1GE5A 1I73A 2JT6A 4H2EA 1D7XA 1G9KA 5D2BA 1GO7P 2OW9A 3SHIA 1WNIA 2D1NA 3KMEA 1QJIA 2WO9A 3EHYA 1MNCA 3LK8A 1OM8A 1DMTA 1CQRA 2MZEA 3DNGA 3LUMA 3B8ZA 2JNPA 1S4BP 2AIGP 4H76A 4PKWA 1MMRA 3AYUA 3LUNA 1K7GA 1ND1A 1GE7A 4L6TA 1JJ9A 4XBHA 3KEJA 1I76A 1JAQA 1CGFA 4PKSA 1JKYA 1XUCA 1YCMA 2ERPA 1GKCA 4DD8A 3CKIA 2YIGA 4GWNA 3LGPA 3KECA 4WKIA 4FU4A 3LIRA 1HFCA 4ZR5A 1GE6A 2OW2A 4EFSA 3DSLA 4H1QA 3HBVP 2OY2A 1ZXCA 2OW1A 1JIZA 2FV5A 4PKTA 1JAPA 2K2GA 3ZVSA 2W13A 3I7IA 2OXWA 2AYKA 4AYKA 1GO8P 1XURA 4AIGA 2CLTA 1HY7A 3RTTA 4HMAA 1BSWA 1XFWA 3USNA 1IAAA 2XS4A 1JANA 4JA1A 1B3DA 2D1OA 2JIHA 2WOAA 1XFUA 4IUWA 1CXVA 1ZTQA 1UEAA 3KEKA 1GXDA 4H84A 1JH1A 3EHXA 1OMJA 4CTHA 2X3AA 1CAQA 3F1AA 3KRYA 5L79A 3EDIA 3AIGA 3B2ZA 1OS9A 3L0VA 1J7NA 4WZVA 4H3XA 1Y8JA 1MMBA 4AUOA 3F19A 1KUHA 2X3BA 3N2UA 1CGEA 5D1SA 4L19A 1G12A 3MA2A 2PJTA 1C3IA 2DW2A 5D7WA 1MMQA 1YQYA 3LJGA 2OY4A 1HV5A 1O0QA 3HYGA 2X7MA 5I4OA 1SMPA 2K9CA 2DDFA 3AYKA 3F16A 1G4KA 1PWVA 5I0LA 3HB2P 4J4MA 1I1IP 3O64A 4G0DA 1KBCA 1SLNA 4HX3A 2V4BA 3LE9A 3G42A 4I35A 2DW0A 4GR3A 1BZSA 3LMCA 1B8YA 3K7NA 2I47A 3F15A 5CXAA 2Y6DA 4JP4A 1SRPA 2TCLA 4H82A 1JIWP 3KWVC 3VTGA 4PKRA 1Y93A 3EWJA 5I3MA 1HTDA 4ILWD 3F18A 1HFSA
chains in the Genus database with same CATH superfamily
1XUDA 3DL1A 4A7BA 1IAGA 3DWBA 1SATA 1OM7A 1MMPA 1G49A 1A86A 3ZUKA 1SLMA 3I7GA 1OM6A 4H30A 1ROSA 1QUAA 4QKZA 2OXUA 3NX7A 3B92A 3HBUP 1BQQM 1BUDA 1XFZA 1BIWA 4PKQA 1CIZA 2ERQA 2YUFA 5L7FA 3ZXHA 4FXYP 1JK3A 1OS2A 5JMYA 1SU3A 1BQOA 3Q2GA 1R55A 1KAPP 2HU6A 5D1TA 1XFVA 2W12A 3N2VA 5BOTA 5CZMA 1ZS0A 3TVCA 5CUHA 1PWUA 3HY7A 4FXQA 1FBLA 1PWWA 3LQ0A 4PKUA 1USNA 1OO9A 1Q3AA 1QIBA 3P1VA 3KHIA 1KUFA 4L63A 2RJPA 4GUYA 4IJOA 1XFXA 1D5JA 2XS3A 4GF1A 1QJJA 4A3WA 3HDAP 1A85A 3OHOA 4ON1A 1BM6A 2L0RA 2E2DA 1AYKA 2OZRA 3L0TA 1C7KA 1ASTA 3DPFA 3LKAA 2CKIA 4IN9A 2JT5A 2OVXA 3BA0A 3F17A 4I03A 1BKCE 1IABA 4GWMA 2USNA 1PWPA 3ELMA 2DDYA 1C8TA 3HDBA 1G05A 4R3VA 3VI1A 3UVCA 2MZHA 4WKEA 1XFYA 3TS4A 3EDZA 5LABA 1KUGA 1EB6A 5B5PA 3P24A 2MZIA 1R1JA 1JAOA 2MLSA 1H71P 3WV2A 4DV8A 1UMTA 2OW0A 3U1RA 1HOVA 1O0TA 2MLRA 3EDHA 1YOUA 4GR0A 830CA 5D1UA 1IAEA 1OZ9A 1QICA 1R54A 2YB9A 4JIJA 1R1HA 1FM1A 5D3CA 3K7LA 3HY9A 2Y6CA 5BPAA 5I43A 4PKVA 1CGLA 3WV3A 3Q2HA 1BUVM 2O3EA 3TSKA 1KUKA 1R1IA 5I12A 1FLSA 1GKDA 4GQLA 1CK7A 2KRJA 3WV1A 4DF9A 4WF6A 1AKLA 1IADA 2O36A 4L7AA 5H8XA 2A8HA 1Z3JA 2RJQA 2SRTA 2W15A 1PWQA 3LJTA 4Q1LA 1Y0VA 1EAKA 1UTZA 2POJA 4AXQA 3OHLA 2W14A 1RM8A 5BOYA 3V96B 2J83A 3E8RA 4JQGA 1UMSA 1DTHA 2QPJA 966CA 4XM8A 4WK7A 4JPAA 4XM7A 2OVZA 4XM6A 2DW1A 2X3CA 456CA 5I2ZA 1ZXVA 4XCTA 2OXZA 2FV9A 2E3XA 3G5CA 1YP1A 3LEAA 4FVLA 3LJZA 3EDGA 1QIAA 3DPEA 4GR8A 1D8MA 3RTSA 2W0DA 1BKCA 1D8FA 1BKCI 4G9LA 1ZP5A 4DPEA 5B5OA 3LQBA 1EUBA 1AF0A 3O2XA 4H49A 2JSDA 3DTEA 1IACA 1KUIA 3GBOA 1K7QA 1ZVXA 2OI0A 2Z2DA 3LILA 1L6JA 2N8RA 1RMZA 3TT4A 1UTTA 2WO8A 3KMCA 1ATLA 3LIKA 1K7IA 2J0TA 2EROA 1GE5A 1I73A 2JT6A 4H2EA 1D7XA 1G9KA 5D2BA 1GO7P 2OW9A 3SHIA 1WNIA 2D1NA 3KMEA 1QJIA 3DTIA 3DTKA 2WO9A 3EHYA 1MNCA 3LK8A 1OM8A 1DMTA 1CQRA 2MZEA 3DNGA 3LUMA 3B8ZA 2JNPA 1S4BP 2AIGP 4H76A 4PKWA 1MMRA 3AYUA 3LUNA 1K7GA 1ND1A 1GE7A 4L6TA 1JJ9A 4XBHA 3KEJA 1I76A 1JAQA 1CGFA 4PKSA 1JKYA 1XUCA 1YCMA 2ERPA 1GKCA 4DD8A 3CKIA 2YIGA 4GWNA 3LGPA 3KECA 4WKIA 4FU4A 3LIRA 1HFCA 4ZR5A 1GE6A 2OW2A 4EFSA 3DSLA 4H1QA 3HBVP 2OY2A 1ZXCA 2OW1A 1JIZA 2FV5A 4PKTA 1JAPA 2K2GA 3ZVSA 2W13A 3I7IA 2OXWA 2AYKA 4AYKA 1GO8P 1XURA 1XAXA 4AIGA 2CLTA 1XM5A 1HY7A 3RTTA 4HMAA 1BSWA 1XFWA 3USNA 1IAAA 2XS4A 1JANA 4JA1A 1B3DA 2D1OA 2JIHA 2WOAA 1XFUA 4IUWA 1CXVA 1ZTQA 1UEAA 3KEKA 1GXDA 4H84A 1JH1A 3EHXA 1OMJA 4CTHA 2X3AA 1CAQA 3F1AA 3KRYA 5L79A 3EDIA 3AIGA 3B2ZA 1OS9A 3L0VA 1J7NA 4WZVA 4H3XA 1Y8JA 1MMBA 4AUOA 3F19A 1KUHA 2X3BA 3N2UA 1CGEA 5D1SA 4L19A 1TVIA 1G12A 3MA2A 2PJTA 1C3IA 2DW2A 5D7WA 1MMQA 1YQYA 3LJGA 2OY4A 1HV5A 1O0QA 3HYGA 2X7MA 5I4OA 1SMPA 2K9CA 2DDFA 3AYKA 3F16A 1G4KA 1PWVA 5I0LA 3HB2P 4J4MA 1I1IP 3O64A 4G0DA 1KBCA 1SLNA 4HX3A 2V4BA 3LE9A 3G42A 4I35A 2DW0A 4GR3A 1BZSA 3LMCA 1B8YA 3K7NA 2I47A 3F15A 5CXAA 2Y6DA 4JP4A 1SRPA 2TCLA 4H82A 1JIWP 3KWVC 3VTGA 4PKRA 1Y93A 3EWJA 5I3MA 1HTDA 4ILWD 3F18A 1HFSA
chains in the Genus database with same CATH topology
1XUDA 3DL1A 4A7BA 1IAGA 3DWBA 1SATA 1OM7A 1MMPA 1G49A 1A86A 3ZUKA 1SLMA 3I7GA 1OM6A 4H30A 1ROSA 1QUAA 4QKZA 2OXUA 3NX7A 3B92A 3HBUP 1BQQM 1BUDA 1XFZA 1BIWA 4PKQA 1CIZA 2ERQA 2YUFA 5L7FA 3ZXHA 4FXYP 1JK3A 1OS2A 5JMYA 1SU3A 1BQOA 3Q2GA 1R55A 1KAPP 2HU6A 5D1TA 1XFVA 2W12A 3N2VA 5BOTA 5CZMA 1ZS0A 3TVCA 5CUHA 1PWUA 3HY7A 4FXQA 1FBLA 1PWWA 3LQ0A 4PKUA 1USNA 1OO9A 1Q3AA 1QIBA 3P1VA 3KHIA 1KUFA 4L63A 2RJPA 4GUYA 4IJOA 1XFXA 1D5JA 2XS3A 4GF1A 1QJJA 4A3WA 3HDAP 1A85A 3OHOA 4ON1A 1BM6A 2L0RA 2E2DA 1AYKA 2OZRA 3L0TA 1C7KA 1ASTA 3DPFA 3LKAA 2CKIA 4IN9A 2JT5A 2OVXA 3BA0A 3F17A 4I03A 1BKCE 1IABA 4GWMA 2USNA 1PWPA 3ELMA 2DDYA 1C8TA 3HDBA 1G05A 4R3VA 3VI1A 3UVCA 2MZHA 4WKEA 1XFYA 3TS4A 3EDZA 5LABA 1KUGA 1EB6A 5B5PA 3P24A 2MZIA 1R1JA 1JAOA 2MLSA 1H71P 3WV2A 4DV8A 1UMTA 2OW0A 3U1RA 1HOVA 1O0TA 2MLRA 3EDHA 1YOUA 4GR0A 830CA 5D1UA 1IAEA 1QICA 1R54A 2YB9A 4JIJA 1R1HA 1FM1A 5D3CA 3K7LA 3HY9A 2Y6CA 5BPAA 5I43A 4PKVA 1CGLA 3WV3A 3Q2HA 1BUVM 2O3EA 3TSKA 1KUKA 1R1IA 5I12A 1FLSA 1GKDA 4GQLA 1CK7A 2KRJA 3WV1A 4DF9A 4WF6A 1AKLA 1IADA 2O36A 4L7AA 5H8XA 2A8HA 1Z3JA 2RJQA 2SRTA 2W15A 1PWQA 3LJTA 4Q1LA 1Y0VA 1EAKA 1UTZA 2POJA 4AXQA 3OHLA 2W14A 1RM8A 5BOYA 3V96B 2J83A 3E8RA 4JQGA 1UMSA 1DTHA 2QPJA 966CA 4XM8A 4WK7A 4JPAA 4XM7A 2OVZA 4XM6A 2DW1A 2X3CA 456CA 5I2ZA 1ZXVA 4XCTA 2OXZA 2FV9A 2E3XA 3G5CA 1YP1A 3LEAA 4FVLA 3LJZA 3EDGA 1QIAA 3DPEA 4GR8A 1D8MA 3RTSA 2W0DA 1BKCA 1D8FA 1BKCI 4G9LA 1ZP5A 4DPEA 5B5OA 3LQBA 1EUBA 1AF0A 3O2XA 4H49A 2JSDA 3DTEA 1IACA 1KUIA 3GBOA 1K7QA 1ZVXA 2OI0A 2Z2DA 3LILA 1L6JA 2N8RA 1RMZA 3TT4A 1UTTA 2WO8A 3KMCA 1ATLA 3LIKA 1K7IA 2J0TA 2EROA 1GE5A 1I73A 2JT6A 4H2EA 1D7XA 1G9KA 5D2BA 1GO7P 2OW9A 3SHIA 1WNIA 2D1NA 3KMEA 1QJIA 3DTIA 3DTKA 2WO9A 3EHYA 1MNCA 3LK8A 1OM8A 1DMTA 1CQRA 2MZEA 3DNGA 3LUMA 3B8ZA 2JNPA 1S4BP 2AIGP 4H76A 4PKWA 1MMRA 3AYUA 3LUNA 1K7GA 1ND1A 1GE7A 4L6TA 1JJ9A 4XBHA 3KEJA 1I76A 1JAQA 1CGFA 4PKSA 1JKYA 1XUCA 1YCMA 2ERPA 1GKCA 4DD8A 3CKIA 2YIGA 4GWNA 3LGPA 3KECA 4WKIA 4FU4A 3LIRA 1HFCA 4ZR5A 1GE6A 2OW2A 4EFSA 3DSLA 4H1QA 3HBVP 2OY2A 1ZXCA 2OW1A 1JIZA 2FV5A 4PKTA 1JAPA 2K2GA 3ZVSA 2W13A 3I7IA 2OXWA 2AYKA 4AYKA 1GO8P 1XURA 4AIGA 2CLTA 1HY7A 3RTTA 4HMAA 1BSWA 1XFWA 3USNA 1IAAA 2XS4A 1JANA 4JA1A 1B3DA 2D1OA 2JIHA 2WOAA 1XFUA 4IUWA 1CXVA 1ZTQA 1UEAA 3KEKA 1GXDA 4H84A 1JH1A 3EHXA 1OMJA 4CTHA 2X3AA 1CAQA 3F1AA 3KRYA 5L79A 3EDIA 3AIGA 3B2ZA 1OS9A 3L0VA 1J7NA 4WZVA 4H3XA 1Y8JA 1MMBA 4AUOA 3F19A 1KUHA 2X3BA 3N2UA 1CGEA 5D1SA 4L19A 1G12A 3MA2A 2PJTA 1C3IA 2DW2A 5D7WA 1MMQA 1YQYA 3LJGA 2OY4A 1HV5A 1O0QA 3HYGA 2X7MA 5I4OA 1SMPA 2K9CA 2DDFA 3AYKA 3F16A 1G4KA 1PWVA 5I0LA 3HB2P 4J4MA 1I1IP 3O64A 4G0DA 1KBCA 1SLNA 4HX3A 2V4BA 3LE9A 3G42A 4I35A 2DW0A 4GR3A 1BZSA 3LMCA 1B8YA 3K7NA 2I47A 3F15A 5CXAA 2Y6DA 4JP4A 1SRPA 2TCLA 4H82A 1JIWP 3KWVC 3VTGA 4PKRA 1Y93A 3EWJA 5I3MA 1HTDA 4ILWD 3F18A 1HFSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1XUD A;  3DL1 A;  4A7B A;  1IAG A;  3DWB A;  1SAT A;  1OM7 A;  1MMP A;  1G49 A;  1A86 A;  3ZUK A;  1SLM A;  3I7G A;  1OM6 A;  4H30 A;  1ROS A;  1QUA A;  4QKZ A;  2OXU A;  3NX7 A;  3B92 A;  3HBU P;  1BQQ M;  1BUD A;  1XFZ A;  1BIW A;  4PKQ A;  1CIZ A;  2ERQ A;  5L7F A;  3ZXH A;  4FXY P;  1JK3 A;  1OS2 A;  5JMY A;  1SU3 A;  1BQO A;  3Q2G A;  1R55 A;  1KAP P;  2HU6 A;  5D1T A;  1XFV A;  2W12 A;  3N2V A;  5BOT A;  5CZM A;  1ZS0 A;  3TVC A;  5CUH A;  1PWU A;  3HY7 A;  4FXQ A;  1FBL A;  1PWW A;  3LQ0 A;  4PKU A;  1USN A;  1OO9 A;  1Q3A A;  1QIB A;  3P1V A;  3KHI A;  1KUF A;  4L63 A;  2RJP A;  4GUY A;  4IJO A;  1XFX A;  1D5J A;  2XS3 A;  4GF1 A;  1QJJ A;  4A3W A;  3HDA P;  1A85 A;  3OHO A;  4ON1 A;  1BM6 A;  2L0R A;  2E2D A;  1AYK A;  2OZR A;  3L0T A;  1C7K A;  1AST A;  3DPF A;  3LKA A;  2CKI A;  4IN9 A;  2JT5 A;  2OVX A;  3BA0 A;  3F17 A;  4I03 A;  1BKC E;  1IAB A;  4GWM A;  2USN A;  1PWP A;  3ELM A;  2DDY A;  1C8T A;  3HDB A;  1G05 A;  4R3V A;  3VI1 A;  3UVC A;  2MZH A;  4WKE A;  1XFY A;  3TS4 A;  3EDZ A;  5LAB A;  1KUG A;  1EB6 A;  5B5P A;  3P24 A;  2MZI A;  1R1J A;  1JAO A;  2MLS A;  1H71 P;  3WV2 A;  4DV8 A;  1UMT A;  2OW0 A;  3U1R A;  1HOV A;  1O0T A;  2MLR A;  3EDH A;  1YOU A;  4GR0 A;  830C A;  5D1U A;  1IAE A;  1QIC A;  1R54 A;  2YB9 A;  4JIJ A;  1R1H A;  1FM1 A;  5D3C A;  3K7L A;  3HY9 A;  2Y6C A;  5BPA A;  5I43 A;  4PKV A;  1CGL A;  3WV3 A;  3Q2H A;  1BUV M;  2O3E A;  3TSK A;  1KUK A;  1R1I A;  5I12 A;  1FLS A;  1GKD A;  4GQL A;  1CK7 A;  2KRJ A;  3WV1 A;  4DF9 A;  4WF6 A;  1AKL A;  1IAD A;  2O36 A;  5H8X A;  2A8H A;  1Z3J A;  2RJQ A;  2SRT A;  2W15 A;  1PWQ A;  3LJT A;  4Q1L A;  1Y0V A;  1EAK A;  1UTZ A;  2POJ A;  4AXQ A;  3OHL A;  2W14 A;  1RM8 A;  5BOY A;  3V96 B;  2J83 A;  3E8R A;  4JQG A;  1UMS A;  1DTH A;  2QPJ A;  966C A;  4XM8 A;  4WK7 A;  4JPA A;  4XM7 A;  2OVZ A;  4XM6 A;  2DW1 A;  2X3C A;  456C A;  5I2Z A;  1ZXV A;  4XCT A;  2OXZ A;  2FV9 A;  2E3X A;  3G5C A;  1YP1 A;  3LEA A;  4FVL A;  3LJZ A;  3EDG A;  1QIA A;  3DPE A;  4GR8 A;  1D8M A;  3RTS A;  2W0D A;  1BKC A;  1D8F A;  1BKC I;  4G9L A;  1ZP5 A;  4DPE A;  5B5O A;  3LQB A;  1EUB A;  1AF0 A;  3O2X A;  4H49 A;  2JSD A;  1IAC A;  1KUI A;  3GBO A;  1K7Q A;  1ZVX A;  2OI0 A;  2Z2D A;  3LIL A;  1L6J A;  2N8R A;  1RMZ A;  3TT4 A;  1UTT A;  2WO8 A;  3KMC A;  1ATL A;  3LIK A;  1K7I A;  2J0T A;  2ERO A;  1GE5 A;  1I73 A;  2JT6 A;  4H2E A;  1D7X A;  1G9K A;  5D2B A;  1GO7 P;  2OW9 A;  3SHI A;  1WNI A;  2D1N A;  3KME A;  1QJI A;  2WO9 A;  3EHY A;  1MNC A;  3LK8 A;  1OM8 A;  1DMT A;  1CQR A;  2MZE A;  3DNG A;  3LUM A;  3B8Z A;  2JNP A;  1S4B P;  2AIG P;  4H76 A;  4PKW A;  1MMR A;  3AYU A;  3LUN A;  1K7G A;  1ND1 A;  1GE7 A;  4L6T A;  1JJ9 A;  4XBH A;  3KEJ A;  1I76 A;  1JAQ A;  1CGF A;  4PKS A;  1JKY A;  1XUC A;  1YCM A;  2ERP A;  1GKC A;  4DD8 A;  3CKI A;  2YIG A;  4GWN A;  3LGP A;  3KEC A;  4WKI A;  4FU4 A;  3LIR A;  1HFC A;  4ZR5 A;  1GE6 A;  2OW2 A;  4EFS A;  3DSL A;  4H1Q A;  3HBV P;  2OY2 A;  1ZXC A;  2OW1 A;  1JIZ A;  2FV5 A;  4PKT A;  1JAP A;  2K2G A;  3ZVS A;  2W13 A;  3I7I A;  2OXW A;  2AYK A;  4AYK A;  1GO8 P;  1XUR A;  4AIG A;  2CLT A;  1HY7 A;  3RTT A;  4HMA A;  1BSW A;  1XFW A;  3USN A;  1IAA A;  2XS4 A;  1JAN A;  4JA1 A;  1B3D A;  2D1O A;  2JIH A;  2WOA A;  1XFU A;  4IUW A;  1CXV A;  1ZTQ A;  1UEA A;  3KEK A;  1GXD A;  4H84 A;  1JH1 A;  3EHX A;  1OMJ A;  4CTH A;  2X3A A;  1CAQ A;  3F1A A;  3KRY A;  5L79 A;  3EDI A;  3AIG A;  3B2Z A;  1OS9 A;  3L0V A;  1J7N A;  4WZV A;  4H3X A;  1Y8J A;  1MMB A;  4AUO A;  3F19 A;  1KUH A;  2X3B A;  3N2U A;  1CGE A;  5D1S A;  4L19 A;  1G12 A;  3MA2 A;  2PJT A;  1C3I A;  2DW2 A;  5D7W A;  1MMQ A;  1YQY A;  3LJG A;  2OY4 A;  1HV5 A;  1O0Q A;  3HYG A;  2X7M A;  5I4O A;  1SMP A;  2K9C A;  2DDF A;  3AYK A;  3F16 A;  1G4K A;  1PWV A;  5I0L A;  3HB2 P;  4J4M A;  1I1I P;  3O64 A;  4G0D A;  1KBC A;  1SLN A;  4HX3 A;  2V4B A;  3LE9 A;  3G42 A;  4I35 A;  2DW0 A;  4GR3 A;  1BZS A;  3LMC A;  1B8Y A;  3K7N A;  2I47 A;  3F15 A;  5CXA A;  2Y6D A;  4JP4 A;  1SRP A;  2TCL A;  4H82 A;  1JIW P;  3KWV C;  3VTG A;  4PKR A;  1Y93 A;  3EWJ A;  5I3M A;  1HTD A;  4ILW D;  3F18 A;  1HFS A; 
#chains in the Genus database with same CATH topology
 1XUD A;  3DL1 A;  4A7B A;  1IAG A;  3DWB A;  1SAT A;  1OM7 A;  1MMP A;  1G49 A;  1A86 A;  3ZUK A;  1SLM A;  3I7G A;  1OM6 A;  4H30 A;  1ROS A;  1QUA A;  4QKZ A;  2OXU A;  3NX7 A;  3B92 A;  3HBU P;  1BQQ M;  1BUD A;  1XFZ A;  1BIW A;  4PKQ A;  1CIZ A;  2ERQ A;  2YUF A;  5L7F A;  3ZXH A;  4FXY P;  1JK3 A;  1OS2 A;  5JMY A;  1SU3 A;  1BQO A;  3Q2G A;  1R55 A;  1KAP P;  2HU6 A;  5D1T A;  1XFV A;  2W12 A;  3N2V A;  5BOT A;  5CZM A;  1ZS0 A;  3TVC A;  5CUH A;  1PWU A;  3HY7 A;  4FXQ A;  1FBL A;  1PWW A;  3LQ0 A;  4PKU A;  1USN A;  1OO9 A;  1Q3A A;  1QIB A;  3P1V A;  3KHI A;  1KUF A;  4L63 A;  2RJP A;  4GUY A;  4IJO A;  1XFX A;  1D5J A;  2XS3 A;  4GF1 A;  1QJJ A;  4A3W A;  3HDA P;  1A85 A;  3OHO A;  4ON1 A;  1BM6 A;  2L0R A;  2E2D A;  1AYK A;  2OZR A;  3L0T A;  1C7K A;  1AST A;  3DPF A;  3LKA A;  2CKI A;  4IN9 A;  2JT5 A;  2OVX A;  3BA0 A;  3F17 A;  4I03 A;  1BKC E;  1IAB A;  4GWM A;  2USN A;  1PWP A;  3ELM A;  2DDY A;  1C8T A;  3HDB A;  1G05 A;  4R3V A;  3VI1 A;  3UVC A;  2MZH A;  4WKE A;  1XFY A;  3TS4 A;  3EDZ A;  5LAB A;  1KUG A;  1EB6 A;  5B5P A;  3P24 A;  2MZI A;  1R1J A;  1JAO A;  2MLS A;  1H71 P;  3WV2 A;  4DV8 A;  1UMT A;  2OW0 A;  3U1R A;  1HOV A;  1O0T A;  2MLR A;  3EDH A;  1YOU A;  4GR0 A;  830C A;  5D1U A;  1IAE A;  1OZ9 A;  1QIC A;  1R54 A;  2YB9 A;  4JIJ A;  1R1H A;  1FM1 A;  5D3C A;  3K7L A;  3HY9 A;  2Y6C A;  5BPA A;  5I43 A;  4PKV A;  1CGL A;  3WV3 A;  3Q2H A;  1BUV M;  2O3E A;  3TSK A;  1KUK A;  1R1I A;  5I12 A;  1FLS A;  1GKD A;  4GQL A;  1CK7 A;  2KRJ A;  3WV1 A;  4DF9 A;  4WF6 A;  1AKL A;  1IAD A;  2O36 A;  4L7A A;  5H8X A;  2A8H A;  1Z3J A;  2RJQ A;  2SRT A;  2W15 A;  1PWQ A;  3LJT A;  4Q1L A;  1Y0V A;  1EAK A;  1UTZ A;  2POJ A;  4AXQ A;  3OHL A;  2W14 A;  1RM8 A;  5BOY A;  3V96 B;  2J83 A;  3E8R A;  4JQG A;  1UMS A;  1DTH A;  2QPJ A;  966C A;  4XM8 A;  4WK7 A;  4JPA A;  4XM7 A;  2OVZ A;  4XM6 A;  2DW1 A;  2X3C A;  456C A;  5I2Z A;  1ZXV A;  4XCT A;  2OXZ A;  2FV9 A;  2E3X A;  3G5C A;  1YP1 A;  3LEA A;  4FVL A;  3LJZ A;  3EDG A;  1QIA A;  3DPE A;  4GR8 A;  1D8M A;  3RTS A;  2W0D A;  1BKC A;  1D8F A;  1BKC I;  4G9L A;  1ZP5 A;  4DPE A;  5B5O A;  3LQB A;  1EUB A;  1AF0 A;  3O2X A;  4H49 A;  2JSD A;  3DTE A;  1IAC A;  1KUI A;  3GBO A;  1K7Q A;  1ZVX A;  2OI0 A;  2Z2D A;  3LIL A;  1L6J A;  2N8R A;  1RMZ A;  3TT4 A;  1UTT A;  2WO8 A;  3KMC A;  1ATL A;  3LIK A;  1K7I A;  2J0T A;  2ERO A;  1GE5 A;  1I73 A;  2JT6 A;  4H2E A;  1D7X A;  1G9K A;  5D2B A;  1GO7 P;  2OW9 A;  3SHI A;  1WNI A;  2D1N A;  3KME A;  1QJI A;  3DTI A;  3DTK A;  2WO9 A;  3EHY A;  1MNC A;  3LK8 A;  1OM8 A;  1DMT A;  1CQR A;  2MZE A;  3DNG A;  3LUM A;  3B8Z A;  2JNP A;  1S4B P;  2AIG P;  4H76 A;  4PKW A;  1MMR A;  3AYU A;  3LUN A;  1K7G A;  1ND1 A;  1GE7 A;  4L6T A;  1JJ9 A;  4XBH A;  3KEJ A;  1I76 A;  1JAQ A;  1CGF A;  4PKS A;  1JKY A;  1XUC A;  1YCM A;  2ERP A;  1GKC A;  4DD8 A;  3CKI A;  2YIG A;  4GWN A;  3LGP A;  3KEC A;  4WKI A;  4FU4 A;  3LIR A;  1HFC A;  4ZR5 A;  1GE6 A;  2OW2 A;  4EFS A;  3DSL A;  4H1Q A;  3HBV P;  2OY2 A;  1ZXC A;  2OW1 A;  1JIZ A;  2FV5 A;  4PKT A;  1JAP A;  2K2G A;  3ZVS A;  2W13 A;  3I7I A;  2OXW A;  2AYK A;  4AYK A;  1GO8 P;  1XUR A;  1XAX A;  4AIG A;  2CLT A;  1XM5 A;  1HY7 A;  3RTT A;  4HMA A;  1BSW A;  1XFW A;  3USN A;  1IAA A;  2XS4 A;  1JAN A;  4JA1 A;  1B3D A;  2D1O A;  2JIH A;  2WOA A;  1XFU A;  4IUW A;  1CXV A;  1ZTQ A;  1UEA A;  3KEK A;  1GXD A;  4H84 A;  1JH1 A;  3EHX A;  1OMJ A;  4CTH A;  2X3A A;  1CAQ A;  3F1A A;  3KRY A;  5L79 A;  3EDI A;  3AIG A;  3B2Z A;  1OS9 A;  3L0V A;  1J7N A;  4WZV A;  4H3X A;  1Y8J A;  1MMB A;  4AUO A;  3F19 A;  1KUH A;  2X3B A;  3N2U A;  1CGE A;  5D1S A;  4L19 A;  1TVI A;  1G12 A;  3MA2 A;  2PJT A;  1C3I A;  2DW2 A;  5D7W A;  1MMQ A;  1YQY A;  3LJG A;  2OY4 A;  1HV5 A;  1O0Q A;  3HYG A;  2X7M A;  5I4O A;  1SMP A;  2K9C A;  2DDF A;  3AYK A;  3F16 A;  1G4K A;  1PWV A;  5I0L A;  3HB2 P;  4J4M A;  1I1I P;  3O64 A;  4G0D A;  1KBC A;  1SLN A;  4HX3 A;  2V4B A;  3LE9 A;  3G42 A;  4I35 A;  2DW0 A;  4GR3 A;  1BZS A;  3LMC A;  1B8Y A;  3K7N A;  2I47 A;  3F15 A;  5CXA A;  2Y6D A;  4JP4 A;  1SRP A;  2TCL A;  4H82 A;  1JIW P;  3KWV C;  3VTG A;  4PKR A;  1Y93 A;  3EWJ A;  5I3M A;  1HTD A;  4ILW D;  3F18 A;  1HFS A; 
#chains in the Genus database with same CATH homology
 1XUD A;  3DL1 A;  4A7B A;  1IAG A;  3DWB A;  1SAT A;  1OM7 A;  1MMP A;  1G49 A;  1A86 A;  3ZUK A;  1SLM A;  3I7G A;  1OM6 A;  4H30 A;  1ROS A;  1QUA A;  4QKZ A;  2OXU A;  3NX7 A;  3B92 A;  3HBU P;  1BQQ M;  1BUD A;  1XFZ A;  1BIW A;  4PKQ A;  1CIZ A;  2ERQ A;  2YUF A;  5L7F A;  3ZXH A;  4FXY P;  1JK3 A;  1OS2 A;  5JMY A;  1SU3 A;  1BQO A;  3Q2G A;  1R55 A;  1KAP P;  2HU6 A;  5D1T A;  1XFV A;  2W12 A;  3N2V A;  5BOT A;  5CZM A;  1ZS0 A;  3TVC A;  5CUH A;  1PWU A;  3HY7 A;  4FXQ A;  1FBL A;  1PWW A;  3LQ0 A;  4PKU A;  1USN A;  1OO9 A;  1Q3A A;  1QIB A;  3P1V A;  3KHI A;  1KUF A;  4L63 A;  2RJP A;  4GUY A;  4IJO A;  1XFX A;  1D5J A;  2XS3 A;  4GF1 A;  1QJJ A;  4A3W A;  3HDA P;  1A85 A;  3OHO A;  4ON1 A;  1BM6 A;  2L0R A;  2E2D A;  1AYK A;  2OZR A;  3L0T A;  1C7K A;  1AST A;  3DPF A;  3LKA A;  2CKI A;  4IN9 A;  2JT5 A;  2OVX A;  3BA0 A;  3F17 A;  4I03 A;  1BKC E;  1IAB A;  4GWM A;  2USN A;  1PWP A;  3ELM A;  2DDY A;  1C8T A;  3HDB A;  1G05 A;  4R3V A;  3VI1 A;  3UVC A;  2MZH A;  4WKE A;  1XFY A;  3TS4 A;  3EDZ A;  5LAB A;  1KUG A;  1EB6 A;  5B5P A;  3P24 A;  2MZI A;  1R1J A;  1JAO A;  2MLS A;  1H71 P;  3WV2 A;  4DV8 A;  1UMT A;  2OW0 A;  3U1R A;  1HOV A;  1O0T A;  2MLR A;  3EDH A;  1YOU A;  4GR0 A;  830C A;  5D1U A;  1IAE A;  1QIC A;  1R54 A;  2YB9 A;  4JIJ A;  1R1H A;  1FM1 A;  5D3C A;  3K7L A;  3HY9 A;  2Y6C A;  5BPA A;  5I43 A;  4PKV A;  1CGL A;  3WV3 A;  3Q2H A;  1BUV M;  2O3E A;  3TSK A;  1KUK A;  1R1I A;  5I12 A;  1FLS A;  1GKD A;  4GQL A;  1CK7 A;  2KRJ A;  3WV1 A;  4DF9 A;  4WF6 A;  1AKL A;  1IAD A;  2O36 A;  4L7A A;  5H8X A;  2A8H A;  1Z3J A;  2RJQ A;  2SRT A;  2W15 A;  1PWQ A;  3LJT A;  4Q1L A;  1Y0V A;  1EAK A;  1UTZ A;  2POJ A;  4AXQ A;  3OHL A;  2W14 A;  1RM8 A;  5BOY A;  3V96 B;  2J83 A;  3E8R A;  4JQG A;  1UMS A;  1DTH A;  2QPJ A;  966C A;  4XM8 A;  4WK7 A;  4JPA A;  4XM7 A;  2OVZ A;  4XM6 A;  2DW1 A;  2X3C A;  456C A;  5I2Z A;  1ZXV A;  4XCT A;  2OXZ A;  2FV9 A;  2E3X A;  3G5C A;  1YP1 A;  3LEA A;  4FVL A;  3LJZ A;  3EDG A;  1QIA A;  3DPE A;  4GR8 A;  1D8M A;  3RTS A;  2W0D A;  1BKC A;  1D8F A;  1BKC I;  4G9L A;  1ZP5 A;  4DPE A;  5B5O A;  3LQB A;  1EUB A;  1AF0 A;  3O2X A;  4H49 A;  2JSD A;  3DTE A;  1IAC A;  1KUI A;  3GBO A;  1K7Q A;  1ZVX A;  2OI0 A;  2Z2D A;  3LIL A;  1L6J A;  2N8R A;  1RMZ A;  3TT4 A;  1UTT A;  2WO8 A;  3KMC A;  1ATL A;  3LIK A;  1K7I A;  2J0T A;  2ERO A;  1GE5 A;  1I73 A;  2JT6 A;  4H2E A;  1D7X A;  1G9K A;  5D2B A;  1GO7 P;  2OW9 A;  3SHI A;  1WNI A;  2D1N A;  3KME A;  1QJI A;  3DTI A;  3DTK A;  2WO9 A;  3EHY A;  1MNC A;  3LK8 A;  1OM8 A;  1DMT A;  1CQR A;  2MZE A;  3DNG A;  3LUM A;  3B8Z A;  2JNP A;  1S4B P;  2AIG P;  4H76 A;  4PKW A;  1MMR A;  3AYU A;  3LUN A;  1K7G A;  1ND1 A;  1GE7 A;  4L6T A;  1JJ9 A;  4XBH A;  3KEJ A;  1I76 A;  1JAQ A;  1CGF A;  4PKS A;  1JKY A;  1XUC A;  1YCM A;  2ERP A;  1GKC A;  4DD8 A;  3CKI A;  2YIG A;  4GWN A;  3LGP A;  3KEC A;  4WKI A;  4FU4 A;  3LIR A;  1HFC A;  4ZR5 A;  1GE6 A;  2OW2 A;  4EFS A;  3DSL A;  4H1Q A;  3HBV P;  2OY2 A;  1ZXC A;  2OW1 A;  1JIZ A;  2FV5 A;  4PKT A;  1JAP A;  2K2G A;  3ZVS A;  2W13 A;  3I7I A;  2OXW A;  2AYK A;  4AYK A;  1GO8 P;  1XUR A;  4AIG A;  2CLT A;  1HY7 A;  3RTT A;  4HMA A;  1BSW A;  1XFW A;  3USN A;  1IAA A;  2XS4 A;  1JAN A;  4JA1 A;  1B3D A;  2D1O A;  2JIH A;  2WOA A;  1XFU A;  4IUW A;  1CXV A;  1ZTQ A;  1UEA A;  3KEK A;  1GXD A;  4H84 A;  1JH1 A;  3EHX A;  1OMJ A;  4CTH A;  2X3A A;  1CAQ A;  3F1A A;  3KRY A;  5L79 A;  3EDI A;  3AIG A;  3B2Z A;  1OS9 A;  3L0V A;  1J7N A;  4WZV A;  4H3X A;  1Y8J A;  1MMB A;  4AUO A;  3F19 A;  1KUH A;  2X3B A;  3N2U A;  1CGE A;  5D1S A;  4L19 A;  1G12 A;  3MA2 A;  2PJT A;  1C3I A;  2DW2 A;  5D7W A;  1MMQ A;  1YQY A;  3LJG A;  2OY4 A;  1HV5 A;  1O0Q A;  3HYG A;  2X7M A;  5I4O A;  1SMP A;  2K9C A;  2DDF A;  3AYK A;  3F16 A;  1G4K A;  1PWV A;  5I0L A;  3HB2 P;  4J4M A;  1I1I P;  3O64 A;  4G0D A;  1KBC A;  1SLN A;  4HX3 A;  2V4B A;  3LE9 A;  3G42 A;  4I35 A;  2DW0 A;  4GR3 A;  1BZS A;  3LMC A;  1B8Y A;  3K7N A;  2I47 A;  3F15 A;  5CXA A;  2Y6D A;  4JP4 A;  1SRP A;  2TCL A;  4H82 A;  1JIW P;  3KWV C;  3VTG A;  4PKR A;  1Y93 A;  3EWJ A;  5I3M A;  1HTD A;  4ILW D;  3F18 A;  1HFS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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