4GR8A

Crystal structure of the catalytic domain of human mmp12 in complex with selective phosphinic inhibitor rxp470c
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
152
structure length
152
Chain Sequence
KHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
publication title Molecular determinants of a selective matrix metalloprotease-12 inhibitor: insights from crystallography and thermodynamic studies.
pubmed doi rcsb
molecule keywords Macrophage metalloelastase
total genus 44
structure length 152
sequence length 152
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2012-08-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 4gr8A00
4IN9A 2WOAA 3HBUP 3O64A 1R1JA 4QKZA 1KBCA 1HFCA 2DDYA 4XM6A 3HDBA 4XBHA 456CA 3KMCA 3N2VA 3WV2A 1JKYA 4GR3A 4ON1A 3TS4A 2XS4A 3AYKA 3P24A 2USNA 1FM1A 4XCTA 1GKDA 3V96B 3LQBA 3KECA 2AYKA 3LKAA 1UMTA 2OZRA 1OO9A 2FV5A 3ELMA 2ERPA 2E2DA 1CXVA 4PKVA 2E3XA 2DW2A 1PWUA 3KRYA 3K7NA 3KEJA 1OS2A 4H76A 4GF1A 1IACA 1JK3A 1JJ9A 4JIJA 1MMBA 1XFVA 1ZS0A 2MZIA 3EHXA 1QJJA 2FV9A 1C3IA 2K2GA 1GO7P 2JT6A 1HY7A 1PWVA 2HU6A 2OW2A 3DWBA 3Q2GA 2ERQA 1JIWP 1IADA 2X3CA 1JAOA 2D1NA 2OY2A 1H71P 1ROSA 3TSKA 3EDIA 1QICA 2OW0A 1L6JA 4H2EA 1SLMA 4GWNA 4H82A 1R55A 4PKUA 4HMAA 2QPJA 2D1OA 3SHIA 2MZEA 1CIZA 4WK7A 1XFUA 1JANA 2CKIA 2JNPA 1OM7A 5I43A 3LQ0A 1XURA 5D1TA 4AIGA 4H49A 4L6TA 2CLTA 2JSDA 1D8MA 1IABA 3G42A 3LJTA 2DDFA 3B92A 1EUBA 1O0TA 1G4KA 4IUWA 4G9LA 3NX7A 1PWPA 1ZP5A 5D3CA 3LIRA 4L63A 3LMCA 4FXYP 1R1HA 3TVCA 1OMJA 1IAEA 1CGEA 1Q3AA 2X3AA 1BSWA 5I3MA 1CGFA 1KAPP 3LJZA 3L0VA 2PJTA 1C8TA 4G0DA 4FVLA 1BM6A 1Y8JA 3I7GA 1ZXVA 2O36A 3VTGA 1YOUA 3LILA 1KUGA 4HX3A 1G12A 4I03A 1G49A 1GE7A 3RTTA 4AUOA 4FXQA 3K7LA 2EROA 5I12A 3B8ZA 5B5OA 1O0QA 3OHOA 1JIZA 1YP1A 2JIHA 1C7KA 4JPAA 1I1IP 1BUDA 1ASTA 4PKRA 1KUHA 3LIKA 5I4OA 4WF6A 4GUYA 3LUMA 1GO8P 1B3DA 1OM8A 4DPEA 4ZR5A 1ND1A 1SU3A 1ZVXA 5BOTA 2OXWA 2DW0A 3HYGA 4IJOA 3WV3A 4AYKA 1QJIA 3DPFA 2OY4A 3EWJA 1CK7A 1ZTQA 4JP4A 2MZHA 1XFXA 1A85A 3F19A 1Y93A 3DPEA 3L0TA 2WO8A 2OXUA 2MLRA 4FU4A 4PKQA 4EFSA 1ATLA 4H30A 1MMPA 3ZUKA 4PKTA 1R1IA 3KHIA 5D7WA 2YB9A 3N2UA 1SATA 2I47A 1Z3JA 2Y6DA 3TT4A 1AYKA 1ZXCA 2TCLA 1K7GA 5D1SA 3KEKA 4WKEA 830CA 1WNIA 5BOYA 2V4BA 1SLNA 2OI0A 2OW9A 1HFSA 3O2XA 2Z2DA 1BZSA 3OHLA 1D5JA 1XUDA 4CTHA 2Y6CA 4DV8A 4GQLA 3U1RA 2XS3A 1HOVA 3I7IA 1G9KA 1D8FA 3P1VA 2DW1A 1MMQA 1MNCA 2O3EA 1B8YA 1XUCA 2YIGA 2W14A 4I35A 1D7XA 3HY7A 3HDAP 3LE9A 4A7BA 1JAQA 3EDZA 3UVCA 1CGLA 5L7FA 1A86A 1QIBA 2X3BA 4ILWD 4XM7A 5D1UA 4JQGA 1RMZA 1GXDA 3WV1A 1YCMA 2SRTA 3B2ZA 3EHYA 2W12A 5B5PA 2RJQA 1UMSA 3F1AA 3E8RA 1MMRA 4H84A 4J4MA 1FBLA 2WO9A 1HV5A 3HY9A 3F17A 1J7NA 2K9CA 3DNGA 1XFYA 3F16A 5CXAA 2OXZA 3LJGA 1QUAA 1UEAA 1R54A 3DL1A 2W0DA 1XFWA 1DTHA 5I2ZA 1GE5A 2RJPA 1UTTA 4WZVA 1JH1A 2OW1A 3F18A 1I73A 4AXQA 1CAQA 1HTDA 4DD8A 1K7QA 3VI1A 1FLSA 1OM6A 2W13A 5H8XA 3F15A 3HBVP 1S4BP 1G05A 3LGPA 2J83A 1JAPA 1SRPA 2AIGP 1BKCI 3GBOA 3LEAA 1EAKA 3LK8A 1PWWA 1BUVM 3LUNA 1IAAA 2JT5A 1AKLA 3ZXHA 4R3VA 1AF0A 1XFZA 4DF9A 3BA0A 3AIGA 2W15A 4WKIA 2X7MA 2J0TA 3RTSA 3ZVSA 4H3XA 2L0RA 4JA1A 3CKIA 3DSLA 4GWMA 4PKSA 1Y0VA 2A8HA 2MLSA 1SMPA 1EB6A 2KRJA 3KWVC 4Q1LA 1KUIA 3KMEA 4PKWA 3HB2P 1RM8A 1UTZA 5CZMA 4GR8A 1BKCE 5D2BA 5L79A 1BKCA 1CQRA 5JMYA 1KUKA 2OVXA 5CUHA 1DMTA 1GE6A 1KUFA 2OVZA 5I0LA 3USNA 3EDHA 1IAGA 4A3WA 1BQOA 4GR0A 4XM8A 1I76A 1GKCA 1K7IA 4L19A 1USNA 2POJA 3G5CA 5LABA 1OS9A 1QIAA 1BQQM 3MA2A 1PWQA 3EDGA 1BIWA 2N8RA 3AYUA 3Q2HA 5BPAA 4H1QA 966CA 1YQYA
chains in the Genus database with same CATH superfamily
4IN9A 2WOAA 3HBUP 3O64A 1R1JA 4QKZA 1KBCA 1HFCA 2DDYA 4XM6A 3HDBA 4XBHA 456CA 3KMCA 3N2VA 3WV2A 1JKYA 4GR3A 4ON1A 3TS4A 2XS4A 3AYKA 1XAXA 3P24A 2USNA 1FM1A 4XCTA 1GKDA 3V96B 3LQBA 3KECA 2AYKA 3LKAA 1UMTA 2OZRA 1OO9A 2FV5A 3ELMA 2ERPA 2E2DA 1CXVA 4PKVA 2E3XA 2DW2A 1PWUA 3KRYA 3K7NA 3KEJA 1OS2A 4H76A 4GF1A 1IACA 1JK3A 1JJ9A 4JIJA 1MMBA 1XFVA 1ZS0A 2MZIA 3EHXA 1QJJA 1TVIA 2FV9A 1C3IA 2K2GA 1GO7P 2JT6A 1HY7A 1PWVA 2HU6A 3DTKA 2OW2A 3DWBA 3Q2GA 2ERQA 1JIWP 1IADA 2X3CA 1JAOA 2D1NA 2OY2A 1H71P 1ROSA 3TSKA 3EDIA 1QICA 2OW0A 1L6JA 4H2EA 1SLMA 4GWNA 4H82A 1R55A 4PKUA 4HMAA 2QPJA 2D1OA 3SHIA 2MZEA 1CIZA 4WK7A 1XFUA 1JANA 2CKIA 2JNPA 1OM7A 5I43A 3LQ0A 1XURA 5D1TA 4AIGA 3DTEA 4H49A 4L6TA 2CLTA 2JSDA 1D8MA 1IABA 3G42A 3LJTA 2DDFA 3B92A 1EUBA 1O0TA 1G4KA 4IUWA 4G9LA 3NX7A 1PWPA 1ZP5A 5D3CA 3LIRA 4L63A 3LMCA 4FXYP 1R1HA 3TVCA 1OMJA 1IAEA 1CGEA 1Q3AA 2X3AA 1BSWA 5I3MA 1CGFA 1KAPP 3LJZA 3L0VA 2PJTA 1C8TA 4G0DA 4FVLA 1BM6A 1Y8JA 1XM5A 3I7GA 1ZXVA 2O36A 3VTGA 1YOUA 3LILA 1KUGA 4HX3A 1G12A 4I03A 1G49A 1GE7A 3RTTA 4AUOA 4FXQA 3K7LA 2EROA 5I12A 3B8ZA 5B5OA 1O0QA 3OHOA 1JIZA 1YP1A 2JIHA 1C7KA 4JPAA 1I1IP 1BUDA 1ASTA 4PKRA 1KUHA 3LIKA 5I4OA 4WF6A 4GUYA 3LUMA 1GO8P 1B3DA 1OM8A 4DPEA 4ZR5A 1ND1A 1SU3A 1ZVXA 5BOTA 2OXWA 2DW0A 3HYGA 4IJOA 3WV3A 4AYKA 1QJIA 3DPFA 2OY4A 3EWJA 1CK7A 1ZTQA 1OZ9A 4JP4A 2MZHA 1XFXA 1A85A 3F19A 1Y93A 3DPEA 3L0TA 2WO8A 2OXUA 2MLRA 4FU4A 4PKQA 4EFSA 1ATLA 4H30A 1MMPA 3ZUKA 4PKTA 1R1IA 3KHIA 5D7WA 2YB9A 3N2UA 1SATA 2I47A 1Z3JA 2Y6DA 3TT4A 1AYKA 1ZXCA 2TCLA 1K7GA 5D1SA 3KEKA 4WKEA 830CA 1WNIA 5BOYA 2V4BA 1SLNA 2OI0A 2OW9A 1HFSA 3O2XA 2Z2DA 1BZSA 3OHLA 1D5JA 1XUDA 4CTHA 2Y6CA 4DV8A 4GQLA 3U1RA 2XS3A 1HOVA 3I7IA 1G9KA 1D8FA 3P1VA 2DW1A 1MMQA 1MNCA 2O3EA 1B8YA 1XUCA 2YIGA 2W14A 4I35A 1D7XA 3HY7A 3HDAP 3LE9A 4A7BA 1JAQA 3EDZA 3UVCA 1CGLA 5L7FA 1A86A 1QIBA 2X3BA 4ILWD 4XM7A 5D1UA 4JQGA 1RMZA 1GXDA 3WV1A 1YCMA 2SRTA 3B2ZA 3EHYA 2W12A 5B5PA 2RJQA 1UMSA 3F1AA 3E8RA 1MMRA 4H84A 4J4MA 1FBLA 2WO9A 1HV5A 3HY9A 3F17A 1J7NA 2K9CA 3DNGA 1XFYA 3F16A 5CXAA 2OXZA 2YUFA 3LJGA 1QUAA 1UEAA 1R54A 3DL1A 2W0DA 1XFWA 1DTHA 5I2ZA 1GE5A 2RJPA 1UTTA 4WZVA 1JH1A 2OW1A 3F18A 1I73A 4AXQA 1CAQA 1HTDA 4DD8A 1K7QA 3VI1A 1FLSA 1OM6A 2W13A 5H8XA 3F15A 3HBVP 1S4BP 1G05A 3LGPA 2J83A 1JAPA 1SRPA 2AIGP 1BKCI 3GBOA 3LEAA 1EAKA 1PWWA 3LK8A 4L7AA 1BUVM 3LUNA 1IAAA 2JT5A 1AKLA 3ZXHA 4R3VA 1AF0A 1XFZA 4DF9A 3BA0A 3AIGA 2W15A 4WKIA 2X7MA 2J0TA 3RTSA 3ZVSA 4H3XA 2L0RA 4JA1A 3CKIA 3DSLA 4GWMA 4PKSA 1Y0VA 2A8HA 2MLSA 1SMPA 1EB6A 2KRJA 3KWVC 4Q1LA 1KUIA 3KMEA 4PKWA 3HB2P 1RM8A 1UTZA 5CZMA 4GR8A 1BKCE 5D2BA 5L79A 1BKCA 1CQRA 5JMYA 1KUKA 2OVXA 5CUHA 1DMTA 1GE6A 1KUFA 2OVZA 5I0LA 3USNA 3EDHA 1IAGA 4A3WA 1BQOA 4GR0A 4XM8A 1I76A 1GKCA 1K7IA 4L19A 1USNA 2POJA 3G5CA 5LABA 1OS9A 1QIAA 1BQQM 3MA2A 1PWQA 3DTIA 3EDGA 1BIWA 2N8RA 3AYUA 3Q2HA 5BPAA 4H1QA 966CA 1YQYA
chains in the Genus database with same CATH topology
4IN9A 2WOAA 3HBUP 3O64A 1R1JA 4QKZA 1KBCA 1HFCA 2DDYA 4XM6A 3HDBA 4XBHA 456CA 3KMCA 3N2VA 3WV2A 1JKYA 4GR3A 4ON1A 3TS4A 2XS4A 3AYKA 3P24A 2USNA 1FM1A 4XCTA 1GKDA 3V96B 3LQBA 3KECA 2AYKA 3LKAA 1UMTA 2OZRA 1OO9A 2FV5A 3ELMA 2ERPA 2E2DA 1CXVA 4PKVA 2E3XA 2DW2A 1PWUA 3KRYA 3K7NA 3KEJA 1OS2A 4H76A 4GF1A 1IACA 1JK3A 1JJ9A 4JIJA 1MMBA 1XFVA 1ZS0A 2MZIA 3EHXA 1QJJA 2FV9A 1C3IA 2K2GA 1GO7P 2JT6A 1HY7A 1PWVA 2HU6A 3DTKA 2OW2A 3DWBA 3Q2GA 2ERQA 1JIWP 1IADA 2X3CA 1JAOA 2D1NA 2OY2A 1H71P 1ROSA 3TSKA 3EDIA 1QICA 2OW0A 1L6JA 4H2EA 1SLMA 4GWNA 4H82A 1R55A 4PKUA 4HMAA 2QPJA 2D1OA 3SHIA 2MZEA 1CIZA 4WK7A 1XFUA 1JANA 2CKIA 2JNPA 1OM7A 5I43A 3LQ0A 1XURA 5D1TA 4AIGA 3DTEA 4H49A 4L6TA 2CLTA 2JSDA 1D8MA 1IABA 3G42A 3LJTA 2DDFA 3B92A 1EUBA 1O0TA 1G4KA 4IUWA 4G9LA 3NX7A 1PWPA 1ZP5A 5D3CA 3LIRA 4L63A 3LMCA 4FXYP 1R1HA 3TVCA 1OMJA 1IAEA 1CGEA 1Q3AA 2X3AA 1BSWA 5I3MA 1CGFA 1KAPP 3LJZA 3L0VA 2PJTA 1C8TA 4G0DA 4FVLA 1BM6A 1Y8JA 3I7GA 1ZXVA 2O36A 3VTGA 1YOUA 3LILA 1KUGA 4HX3A 1G12A 4I03A 1G49A 1GE7A 3RTTA 4AUOA 4FXQA 3K7LA 2EROA 5I12A 3B8ZA 5B5OA 1O0QA 3OHOA 1JIZA 1YP1A 2JIHA 1C7KA 4JPAA 1I1IP 1BUDA 1ASTA 4PKRA 1KUHA 3LIKA 5I4OA 4WF6A 4GUYA 3LUMA 1GO8P 1B3DA 1OM8A 4DPEA 4ZR5A 1ND1A 1SU3A 1ZVXA 5BOTA 2OXWA 2DW0A 3HYGA 4IJOA 3WV3A 4AYKA 1QJIA 3DPFA 2OY4A 3EWJA 1CK7A 1ZTQA 4JP4A 2MZHA 1XFXA 1A85A 3F19A 1Y93A 3DPEA 3L0TA 2WO8A 2OXUA 2MLRA 4FU4A 4PKQA 4EFSA 1ATLA 4H30A 1MMPA 3ZUKA 4PKTA 1R1IA 3KHIA 5D7WA 2YB9A 3N2UA 1SATA 2I47A 1Z3JA 2Y6DA 3TT4A 1AYKA 1ZXCA 2TCLA 1K7GA 5D1SA 3KEKA 4WKEA 830CA 1WNIA 5BOYA 2V4BA 1SLNA 2OI0A 2OW9A 1HFSA 3O2XA 2Z2DA 1BZSA 3OHLA 1D5JA 1XUDA 4CTHA 2Y6CA 4DV8A 4GQLA 3U1RA 2XS3A 1HOVA 3I7IA 1G9KA 1D8FA 3P1VA 2DW1A 1MMQA 1MNCA 2O3EA 1B8YA 1XUCA 2YIGA 2W14A 4I35A 1D7XA 3HY7A 3HDAP 3LE9A 4A7BA 1JAQA 3EDZA 3UVCA 1CGLA 5L7FA 1A86A 1QIBA 2X3BA 4ILWD 4XM7A 5D1UA 4JQGA 1RMZA 1GXDA 3WV1A 1YCMA 2SRTA 3B2ZA 3EHYA 2W12A 5B5PA 2RJQA 1UMSA 3F1AA 3E8RA 1MMRA 4H84A 4J4MA 1FBLA 2WO9A 1HV5A 3HY9A 3F17A 1J7NA 2K9CA 3DNGA 1XFYA 3F16A 5CXAA 2OXZA 2YUFA 3LJGA 1QUAA 1UEAA 1R54A 3DL1A 2W0DA 1XFWA 1DTHA 5I2ZA 1GE5A 2RJPA 1UTTA 4WZVA 1JH1A 2OW1A 3F18A 1I73A 4AXQA 1CAQA 1HTDA 4DD8A 1K7QA 3VI1A 1FLSA 1OM6A 2W13A 5H8XA 3F15A 3HBVP 1S4BP 1G05A 3LGPA 2J83A 1JAPA 1SRPA 2AIGP 1BKCI 3GBOA 3LEAA 1EAKA 1PWWA 3LK8A 4L7AA 1BUVM 3LUNA 1IAAA 2JT5A 1AKLA 3ZXHA 4R3VA 1AF0A 1XFZA 4DF9A 3BA0A 3AIGA 2W15A 4WKIA 2X7MA 2J0TA 3RTSA 3ZVSA 4H3XA 2L0RA 4JA1A 3CKIA 3DSLA 4GWMA 4PKSA 1Y0VA 2A8HA 2MLSA 1SMPA 1EB6A 2KRJA 3KWVC 4Q1LA 1KUIA 3KMEA 4PKWA 3HB2P 1RM8A 1UTZA 5CZMA 4GR8A 1BKCE 5D2BA 5L79A 1BKCA 1CQRA 5JMYA 1KUKA 2OVXA 5CUHA 1DMTA 1GE6A 1KUFA 2OVZA 5I0LA 3USNA 3EDHA 1IAGA 4A3WA 1BQOA 4GR0A 4XM8A 1I76A 1GKCA 1K7IA 4L19A 1USNA 2POJA 3G5CA 5LABA 1OS9A 1QIAA 1BQQM 3MA2A 1PWQA 3DTIA 3EDGA 1BIWA 2N8RA 3AYUA 3Q2HA 5BPAA 4H1QA 966CA 1YQYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IN9 A;  2WOA A;  3HBU P;  3O64 A;  1R1J A;  4QKZ A;  1KBC A;  1HFC A;  2DDY A;  4XM6 A;  3HDB A;  4XBH A;  456C A;  3KMC A;  3N2V A;  3WV2 A;  1JKY A;  4GR3 A;  4ON1 A;  3TS4 A;  2XS4 A;  3AYK A;  3P24 A;  2USN A;  1FM1 A;  4XCT A;  1GKD A;  3V96 B;  3LQB A;  3KEC A;  2AYK A;  3LKA A;  1UMT A;  2OZR A;  1OO9 A;  2FV5 A;  3ELM A;  2ERP A;  2E2D A;  1CXV A;  4PKV A;  2E3X A;  2DW2 A;  1PWU A;  3KRY A;  3K7N A;  3KEJ A;  1OS2 A;  4H76 A;  4GF1 A;  1IAC A;  1JK3 A;  1JJ9 A;  4JIJ A;  1MMB A;  1XFV A;  1ZS0 A;  2MZI A;  3EHX A;  1QJJ A;  2FV9 A;  1C3I A;  2K2G A;  1GO7 P;  2JT6 A;  1HY7 A;  1PWV A;  2HU6 A;  2OW2 A;  3DWB A;  3Q2G A;  2ERQ A;  1JIW P;  1IAD A;  2X3C A;  1JAO A;  2D1N A;  2OY2 A;  1H71 P;  1ROS A;  3TSK A;  3EDI A;  1QIC A;  2OW0 A;  1L6J A;  4H2E A;  1SLM A;  4GWN A;  4H82 A;  1R55 A;  4PKU A;  4HMA A;  2QPJ A;  2D1O A;  3SHI A;  2MZE A;  1CIZ A;  4WK7 A;  1XFU A;  1JAN A;  2CKI A;  2JNP A;  1OM7 A;  5I43 A;  3LQ0 A;  1XUR A;  5D1T A;  4AIG A;  4H49 A;  4L6T A;  2CLT A;  2JSD A;  1D8M A;  1IAB A;  3G42 A;  3LJT A;  2DDF A;  3B92 A;  1EUB A;  1O0T A;  1G4K A;  4IUW A;  4G9L A;  3NX7 A;  1PWP A;  1ZP5 A;  5D3C A;  3LIR A;  4L63 A;  3LMC A;  4FXY P;  1R1H A;  3TVC A;  1OMJ A;  1IAE A;  1CGE A;  1Q3A A;  2X3A A;  1BSW A;  5I3M A;  1CGF A;  1KAP P;  3LJZ A;  3L0V A;  2PJT A;  1C8T A;  4G0D A;  4FVL A;  1BM6 A;  1Y8J A;  3I7G A;  1ZXV A;  2O36 A;  3VTG A;  1YOU A;  3LIL A;  1KUG A;  4HX3 A;  1G12 A;  4I03 A;  1G49 A;  1GE7 A;  3RTT A;  4AUO A;  4FXQ A;  3K7L A;  2ERO A;  5I12 A;  3B8Z A;  5B5O A;  1O0Q A;  3OHO A;  1JIZ A;  1YP1 A;  2JIH A;  1C7K A;  4JPA A;  1I1I P;  1BUD A;  1AST A;  4PKR A;  1KUH A;  3LIK A;  5I4O A;  4WF6 A;  4GUY A;  3LUM A;  1GO8 P;  1B3D A;  1OM8 A;  4DPE A;  4ZR5 A;  1ND1 A;  1SU3 A;  1ZVX A;  5BOT A;  2OXW A;  2DW0 A;  3HYG A;  4IJO A;  3WV3 A;  4AYK A;  1QJI A;  3DPF A;  2OY4 A;  3EWJ A;  1CK7 A;  1ZTQ A;  4JP4 A;  2MZH A;  1XFX A;  1A85 A;  3F19 A;  1Y93 A;  3DPE A;  3L0T A;  2WO8 A;  2OXU A;  2MLR A;  4FU4 A;  4PKQ A;  4EFS A;  1ATL A;  4H30 A;  1MMP A;  3ZUK A;  4PKT A;  1R1I A;  3KHI A;  5D7W A;  2YB9 A;  3N2U A;  1SAT A;  2I47 A;  1Z3J A;  2Y6D A;  3TT4 A;  1AYK A;  1ZXC A;  2TCL A;  1K7G A;  5D1S A;  3KEK A;  4WKE A;  830C A;  1WNI A;  5BOY A;  2V4B A;  1SLN A;  2OI0 A;  2OW9 A;  1HFS A;  3O2X A;  2Z2D A;  1BZS A;  3OHL A;  1D5J A;  1XUD A;  4CTH A;  2Y6C A;  4DV8 A;  4GQL A;  3U1R A;  2XS3 A;  1HOV A;  3I7I A;  1G9K A;  1D8F A;  3P1V A;  2DW1 A;  1MMQ A;  1MNC A;  2O3E A;  1B8Y A;  1XUC A;  2YIG A;  2W14 A;  4I35 A;  1D7X A;  3HY7 A;  3HDA P;  3LE9 A;  4A7B A;  1JAQ A;  3EDZ A;  3UVC A;  1CGL A;  5L7F A;  1A86 A;  1QIB A;  2X3B A;  4ILW D;  4XM7 A;  5D1U A;  4JQG A;  1RMZ A;  1GXD A;  3WV1 A;  1YCM A;  2SRT A;  3B2Z A;  3EHY A;  2W12 A;  5B5P A;  2RJQ A;  1UMS A;  3F1A A;  3E8R A;  1MMR A;  4H84 A;  4J4M A;  1FBL A;  2WO9 A;  1HV5 A;  3HY9 A;  3F17 A;  1J7N A;  2K9C A;  3DNG A;  1XFY A;  3F16 A;  5CXA A;  2OXZ A;  3LJG A;  1QUA A;  1UEA A;  1R54 A;  3DL1 A;  2W0D A;  1XFW A;  1DTH A;  5I2Z A;  1GE5 A;  2RJP A;  1UTT A;  4WZV A;  1JH1 A;  2OW1 A;  3F18 A;  1I73 A;  4AXQ A;  1CAQ A;  1HTD A;  4DD8 A;  1K7Q A;  3VI1 A;  1FLS A;  1OM6 A;  2W13 A;  5H8X A;  3F15 A;  3HBV P;  1S4B P;  1G05 A;  3LGP A;  2J83 A;  1JAP A;  1SRP A;  2AIG P;  1BKC I;  3GBO A;  3LEA A;  1EAK A;  3LK8 A;  1PWW A;  1BUV M;  3LUN A;  1IAA A;  2JT5 A;  1AKL A;  3ZXH A;  4R3V A;  1AF0 A;  1XFZ A;  4DF9 A;  3BA0 A;  3AIG A;  2W15 A;  4WKI A;  2X7M A;  2J0T A;  3RTS A;  3ZVS A;  4H3X A;  2L0R A;  4JA1 A;  3CKI A;  3DSL A;  4GWM A;  4PKS A;  1Y0V A;  2A8H A;  2MLS A;  1SMP A;  1EB6 A;  2KRJ A;  3KWV C;  4Q1L A;  1KUI A;  3KME A;  4PKW A;  3HB2 P;  1RM8 A;  1UTZ A;  5CZM A;  4GR8 A;  1BKC E;  5D2B A;  5L79 A;  1BKC A;  1CQR A;  5JMY A;  1KUK A;  2OVX A;  5CUH A;  1DMT A;  1GE6 A;  1KUF A;  2OVZ A;  5I0L A;  3USN A;  3EDH A;  1IAG A;  4A3W A;  1BQO A;  4GR0 A;  4XM8 A;  1I76 A;  1GKC A;  1K7I A;  4L19 A;  1USN A;  2POJ A;  3G5C A;  5LAB A;  1OS9 A;  1QIA A;  1BQQ M;  3MA2 A;  1PWQ A;  3EDG A;  1BIW A;  2N8R A;  3AYU A;  3Q2H A;  5BPA A;  4H1Q A;  966C A;  1YQY A; 
#chains in the Genus database with same CATH topology
 4IN9 A;  2WOA A;  3HBU P;  3O64 A;  1R1J A;  4QKZ A;  1KBC A;  1HFC A;  2DDY A;  4XM6 A;  3HDB A;  4XBH A;  456C A;  3KMC A;  3N2V A;  3WV2 A;  1JKY A;  4GR3 A;  4ON1 A;  3TS4 A;  2XS4 A;  3AYK A;  1XAX A;  3P24 A;  2USN A;  1FM1 A;  4XCT A;  1GKD A;  3V96 B;  3LQB A;  3KEC A;  2AYK A;  3LKA A;  1UMT A;  2OZR A;  1OO9 A;  2FV5 A;  3ELM A;  2ERP A;  2E2D A;  1CXV A;  4PKV A;  2E3X A;  2DW2 A;  1PWU A;  3KRY A;  3K7N A;  3KEJ A;  1OS2 A;  4H76 A;  4GF1 A;  1IAC A;  1JK3 A;  1JJ9 A;  4JIJ A;  1MMB A;  1XFV A;  1ZS0 A;  2MZI A;  3EHX A;  1QJJ A;  1TVI A;  2FV9 A;  1C3I A;  2K2G A;  1GO7 P;  2JT6 A;  1HY7 A;  1PWV A;  2HU6 A;  3DTK A;  2OW2 A;  3DWB A;  3Q2G A;  2ERQ A;  1JIW P;  1IAD A;  2X3C A;  1JAO A;  2D1N A;  2OY2 A;  1H71 P;  1ROS A;  3TSK A;  3EDI A;  1QIC A;  2OW0 A;  1L6J A;  4H2E A;  1SLM A;  4GWN A;  4H82 A;  1R55 A;  4PKU A;  4HMA A;  2QPJ A;  2D1O A;  3SHI A;  2MZE A;  1CIZ A;  4WK7 A;  1XFU A;  1JAN A;  2CKI A;  2JNP A;  1OM7 A;  5I43 A;  3LQ0 A;  1XUR A;  5D1T A;  4AIG A;  3DTE A;  4H49 A;  4L6T A;  2CLT A;  2JSD A;  1D8M A;  1IAB A;  3G42 A;  3LJT A;  2DDF A;  3B92 A;  1EUB A;  1O0T A;  1G4K A;  4IUW A;  4G9L A;  3NX7 A;  1PWP A;  1ZP5 A;  5D3C A;  3LIR A;  4L63 A;  3LMC A;  4FXY P;  1R1H A;  3TVC A;  1OMJ A;  1IAE A;  1CGE A;  1Q3A A;  2X3A A;  1BSW A;  5I3M A;  1CGF A;  1KAP P;  3LJZ A;  3L0V A;  2PJT A;  1C8T A;  4G0D A;  4FVL A;  1BM6 A;  1Y8J A;  1XM5 A;  3I7G A;  1ZXV A;  2O36 A;  3VTG A;  1YOU A;  3LIL A;  1KUG A;  4HX3 A;  1G12 A;  4I03 A;  1G49 A;  1GE7 A;  3RTT A;  4AUO A;  4FXQ A;  3K7L A;  2ERO A;  5I12 A;  3B8Z A;  5B5O A;  1O0Q A;  3OHO A;  1JIZ A;  1YP1 A;  2JIH A;  1C7K A;  4JPA A;  1I1I P;  1BUD A;  1AST A;  4PKR A;  1KUH A;  3LIK A;  5I4O A;  4WF6 A;  4GUY A;  3LUM A;  1GO8 P;  1B3D A;  1OM8 A;  4DPE A;  4ZR5 A;  1ND1 A;  1SU3 A;  1ZVX A;  5BOT A;  2OXW A;  2DW0 A;  3HYG A;  4IJO A;  3WV3 A;  4AYK A;  1QJI A;  3DPF A;  2OY4 A;  3EWJ A;  1CK7 A;  1ZTQ A;  1OZ9 A;  4JP4 A;  2MZH A;  1XFX A;  1A85 A;  3F19 A;  1Y93 A;  3DPE A;  3L0T A;  2WO8 A;  2OXU A;  2MLR A;  4FU4 A;  4PKQ A;  4EFS A;  1ATL A;  4H30 A;  1MMP A;  3ZUK A;  4PKT A;  1R1I A;  3KHI A;  5D7W A;  2YB9 A;  3N2U A;  1SAT A;  2I47 A;  1Z3J A;  2Y6D A;  3TT4 A;  1AYK A;  1ZXC A;  2TCL A;  1K7G A;  5D1S A;  3KEK A;  4WKE A;  830C A;  1WNI A;  5BOY A;  2V4B A;  1SLN A;  2OI0 A;  2OW9 A;  1HFS A;  3O2X A;  2Z2D A;  1BZS A;  3OHL A;  1D5J A;  1XUD A;  4CTH A;  2Y6C A;  4DV8 A;  4GQL A;  3U1R A;  2XS3 A;  1HOV A;  3I7I A;  1G9K A;  1D8F A;  3P1V A;  2DW1 A;  1MMQ A;  1MNC A;  2O3E A;  1B8Y A;  1XUC A;  2YIG A;  2W14 A;  4I35 A;  1D7X A;  3HY7 A;  3HDA P;  3LE9 A;  4A7B A;  1JAQ A;  3EDZ A;  3UVC A;  1CGL A;  5L7F A;  1A86 A;  1QIB A;  2X3B A;  4ILW D;  4XM7 A;  5D1U A;  4JQG A;  1RMZ A;  1GXD A;  3WV1 A;  1YCM A;  2SRT A;  3B2Z A;  3EHY A;  2W12 A;  5B5P A;  2RJQ A;  1UMS A;  3F1A A;  3E8R A;  1MMR A;  4H84 A;  4J4M A;  1FBL A;  2WO9 A;  1HV5 A;  3HY9 A;  3F17 A;  1J7N A;  2K9C A;  3DNG A;  1XFY A;  3F16 A;  5CXA A;  2OXZ A;  2YUF A;  3LJG A;  1QUA A;  1UEA A;  1R54 A;  3DL1 A;  2W0D A;  1XFW A;  1DTH A;  5I2Z A;  1GE5 A;  2RJP A;  1UTT A;  4WZV A;  1JH1 A;  2OW1 A;  3F18 A;  1I73 A;  4AXQ A;  1CAQ A;  1HTD A;  4DD8 A;  1K7Q A;  3VI1 A;  1FLS A;  1OM6 A;  2W13 A;  5H8X A;  3F15 A;  3HBV P;  1S4B P;  1G05 A;  3LGP A;  2J83 A;  1JAP A;  1SRP A;  2AIG P;  1BKC I;  3GBO A;  3LEA A;  1EAK A;  1PWW A;  3LK8 A;  4L7A A;  1BUV M;  3LUN A;  1IAA A;  2JT5 A;  1AKL A;  3ZXH A;  4R3V A;  1AF0 A;  1XFZ A;  4DF9 A;  3BA0 A;  3AIG A;  2W15 A;  4WKI A;  2X7M A;  2J0T A;  3RTS A;  3ZVS A;  4H3X A;  2L0R A;  4JA1 A;  3CKI A;  3DSL A;  4GWM A;  4PKS A;  1Y0V A;  2A8H A;  2MLS A;  1SMP A;  1EB6 A;  2KRJ A;  3KWV C;  4Q1L A;  1KUI A;  3KME A;  4PKW A;  3HB2 P;  1RM8 A;  1UTZ A;  5CZM A;  4GR8 A;  1BKC E;  5D2B A;  5L79 A;  1BKC A;  1CQR A;  5JMY A;  1KUK A;  2OVX A;  5CUH A;  1DMT A;  1GE6 A;  1KUF A;  2OVZ A;  5I0L A;  3USN A;  3EDH A;  1IAG A;  4A3W A;  1BQO A;  4GR0 A;  4XM8 A;  1I76 A;  1GKC A;  1K7I A;  4L19 A;  1USN A;  2POJ A;  3G5C A;  5LAB A;  1OS9 A;  1QIA A;  1BQQ M;  3MA2 A;  1PWQ A;  3DTI A;  3EDG A;  1BIW A;  2N8R A;  3AYU A;  3Q2H A;  5BPA A;  4H1Q A;  966C A;  1YQY A; 
#chains in the Genus database with same CATH homology
 4IN9 A;  2WOA A;  3HBU P;  3O64 A;  1R1J A;  4QKZ A;  1KBC A;  1HFC A;  2DDY A;  4XM6 A;  3HDB A;  4XBH A;  456C A;  3KMC A;  3N2V A;  3WV2 A;  1JKY A;  4GR3 A;  4ON1 A;  3TS4 A;  2XS4 A;  3AYK A;  3P24 A;  2USN A;  1FM1 A;  4XCT A;  1GKD A;  3V96 B;  3LQB A;  3KEC A;  2AYK A;  3LKA A;  1UMT A;  2OZR A;  1OO9 A;  2FV5 A;  3ELM A;  2ERP A;  2E2D A;  1CXV A;  4PKV A;  2E3X A;  2DW2 A;  1PWU A;  3KRY A;  3K7N A;  3KEJ A;  1OS2 A;  4H76 A;  4GF1 A;  1IAC A;  1JK3 A;  1JJ9 A;  4JIJ A;  1MMB A;  1XFV A;  1ZS0 A;  2MZI A;  3EHX A;  1QJJ A;  2FV9 A;  1C3I A;  2K2G A;  1GO7 P;  2JT6 A;  1HY7 A;  1PWV A;  2HU6 A;  3DTK A;  2OW2 A;  3DWB A;  3Q2G A;  2ERQ A;  1JIW P;  1IAD A;  2X3C A;  1JAO A;  2D1N A;  2OY2 A;  1H71 P;  1ROS A;  3TSK A;  3EDI A;  1QIC A;  2OW0 A;  1L6J A;  4H2E A;  1SLM A;  4GWN A;  4H82 A;  1R55 A;  4PKU A;  4HMA A;  2QPJ A;  2D1O A;  3SHI A;  2MZE A;  1CIZ A;  4WK7 A;  1XFU A;  1JAN A;  2CKI A;  2JNP A;  1OM7 A;  5I43 A;  3LQ0 A;  1XUR A;  5D1T A;  4AIG A;  3DTE A;  4H49 A;  4L6T A;  2CLT A;  2JSD A;  1D8M A;  1IAB A;  3G42 A;  3LJT A;  2DDF A;  3B92 A;  1EUB A;  1O0T A;  1G4K A;  4IUW A;  4G9L A;  3NX7 A;  1PWP A;  1ZP5 A;  5D3C A;  3LIR A;  4L63 A;  3LMC A;  4FXY P;  1R1H A;  3TVC A;  1OMJ A;  1IAE A;  1CGE A;  1Q3A A;  2X3A A;  1BSW A;  5I3M A;  1CGF A;  1KAP P;  3LJZ A;  3L0V A;  2PJT A;  1C8T A;  4G0D A;  4FVL A;  1BM6 A;  1Y8J A;  3I7G A;  1ZXV A;  2O36 A;  3VTG A;  1YOU A;  3LIL A;  1KUG A;  4HX3 A;  1G12 A;  4I03 A;  1G49 A;  1GE7 A;  3RTT A;  4AUO A;  4FXQ A;  3K7L A;  2ERO A;  5I12 A;  3B8Z A;  5B5O A;  1O0Q A;  3OHO A;  1JIZ A;  1YP1 A;  2JIH A;  1C7K A;  4JPA A;  1I1I P;  1BUD A;  1AST A;  4PKR A;  1KUH A;  3LIK A;  5I4O A;  4WF6 A;  4GUY A;  3LUM A;  1GO8 P;  1B3D A;  1OM8 A;  4DPE A;  4ZR5 A;  1ND1 A;  1SU3 A;  1ZVX A;  5BOT A;  2OXW A;  2DW0 A;  3HYG A;  4IJO A;  3WV3 A;  4AYK A;  1QJI A;  3DPF A;  2OY4 A;  3EWJ A;  1CK7 A;  1ZTQ A;  4JP4 A;  2MZH A;  1XFX A;  1A85 A;  3F19 A;  1Y93 A;  3DPE A;  3L0T A;  2WO8 A;  2OXU A;  2MLR A;  4FU4 A;  4PKQ A;  4EFS A;  1ATL A;  4H30 A;  1MMP A;  3ZUK A;  4PKT A;  1R1I A;  3KHI A;  5D7W A;  2YB9 A;  3N2U A;  1SAT A;  2I47 A;  1Z3J A;  2Y6D A;  3TT4 A;  1AYK A;  1ZXC A;  2TCL A;  1K7G A;  5D1S A;  3KEK A;  4WKE A;  830C A;  1WNI A;  5BOY A;  2V4B A;  1SLN A;  2OI0 A;  2OW9 A;  1HFS A;  3O2X A;  2Z2D A;  1BZS A;  3OHL A;  1D5J A;  1XUD A;  4CTH A;  2Y6C A;  4DV8 A;  4GQL A;  3U1R A;  2XS3 A;  1HOV A;  3I7I A;  1G9K A;  1D8F A;  3P1V A;  2DW1 A;  1MMQ A;  1MNC A;  2O3E A;  1B8Y A;  1XUC A;  2YIG A;  2W14 A;  4I35 A;  1D7X A;  3HY7 A;  3HDA P;  3LE9 A;  4A7B A;  1JAQ A;  3EDZ A;  3UVC A;  1CGL A;  5L7F A;  1A86 A;  1QIB A;  2X3B A;  4ILW D;  4XM7 A;  5D1U A;  4JQG A;  1RMZ A;  1GXD A;  3WV1 A;  1YCM A;  2SRT A;  3B2Z A;  3EHY A;  2W12 A;  5B5P A;  2RJQ A;  1UMS A;  3F1A A;  3E8R A;  1MMR A;  4H84 A;  4J4M A;  1FBL A;  2WO9 A;  1HV5 A;  3HY9 A;  3F17 A;  1J7N A;  2K9C A;  3DNG A;  1XFY A;  3F16 A;  5CXA A;  2OXZ A;  2YUF A;  3LJG A;  1QUA A;  1UEA A;  1R54 A;  3DL1 A;  2W0D A;  1XFW A;  1DTH A;  5I2Z A;  1GE5 A;  2RJP A;  1UTT A;  4WZV A;  1JH1 A;  2OW1 A;  3F18 A;  1I73 A;  4AXQ A;  1CAQ A;  1HTD A;  4DD8 A;  1K7Q A;  3VI1 A;  1FLS A;  1OM6 A;  2W13 A;  5H8X A;  3F15 A;  3HBV P;  1S4B P;  1G05 A;  3LGP A;  2J83 A;  1JAP A;  1SRP A;  2AIG P;  1BKC I;  3GBO A;  3LEA A;  1EAK A;  1PWW A;  3LK8 A;  4L7A A;  1BUV M;  3LUN A;  1IAA A;  2JT5 A;  1AKL A;  3ZXH A;  4R3V A;  1AF0 A;  1XFZ A;  4DF9 A;  3BA0 A;  3AIG A;  2W15 A;  4WKI A;  2X7M A;  2J0T A;  3RTS A;  3ZVS A;  4H3X A;  2L0R A;  4JA1 A;  3CKI A;  3DSL A;  4GWM A;  4PKS A;  1Y0V A;  2A8H A;  2MLS A;  1SMP A;  1EB6 A;  2KRJ A;  3KWV C;  4Q1L A;  1KUI A;  3KME A;  4PKW A;  3HB2 P;  1RM8 A;  1UTZ A;  5CZM A;  4GR8 A;  1BKC E;  5D2B A;  5L79 A;  1BKC A;  1CQR A;  5JMY A;  1KUK A;  2OVX A;  5CUH A;  1DMT A;  1GE6 A;  1KUF A;  2OVZ A;  5I0L A;  3USN A;  3EDH A;  1IAG A;  4A3W A;  1BQO A;  4GR0 A;  4XM8 A;  1I76 A;  1GKC A;  1K7I A;  4L19 A;  1USN A;  2POJ A;  3G5C A;  5LAB A;  1OS9 A;  1QIA A;  1BQQ M;  3MA2 A;  1PWQ A;  3DTI A;  3EDG A;  1BIW A;  2N8R A;  3AYU A;  3Q2H A;  5BPA A;  4H1Q A;  966C A;  1YQY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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