4IJOA

Unraveling hidden allosteric regulatory sites in structurally homologues metalloproteases
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
158
structure length
158
Chain Sequence
GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Unraveling hidden regulatory sites in structurally homologous metalloproteases
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Macrophage metalloelastase
total genus 44
structure length 158
sequence length 158
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2012-12-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 4ijoA00
4L19A 1JANA 1K7QA 2XS4A 1QIBA 5JMYA 4DV8A 1EAKA 1BIWA 1KUKA 1ZXCA 1Y93A 3I7GA 1OM8A 2ERPA 3P1VA 1K7IA 2JSDA 2L0RA 3LIKA 4XCTA 1G05A 2D1NA 1Y8JA 3HB2P 1XURA 4ZR5A 1SRPA 3DPFA 3ZVSA 2OVZA 2E3XA 1A86A 3LJZA 1O0TA 1JIZA 3AYKA 1BUVM 3HY7A 4IJOA 1IAAA 3G42A 830CA 1GXDA 3HDAP 3V96B 4XBHA 2YB9A 3F1AA 1GKDA 2USNA 2MLRA 3G5CA 1BSWA 2JIHA 3VI1A 1BQOA 3TS4A 2CKIA 3LJGA 3UVCA 2J0TA 2W15A 1KUFA 1JIWP 3LE9A 3HBUP 1FLSA 1JAOA 2OXUA 1R55A 1YQYA 1MMPA 3WV3A 3EDIA 2D1OA 5BPAA 2O36A 1KAPP 1RMZA 1ZTQA 1XFXA 5B5PA 4DD8A 3KECA 3RTSA 3KHIA 3KRYA 4L63A 1XUDA 3U1RA 1CGLA 1CAQA 1HFSA 3KEKA 4DF9A 2OW1A 2TCLA 1PWWA 1R54A 1ASTA 3TVCA 1IAGA 4AIGA 1GE5A 4H3XA 2JT5A 1JKYA 1I73A 4H30A 1PWVA 3MA2A 1A85A 3LIRA 3HBVP 1OM7A 1CIZA 2DW0A 4G9LA 1HOVA 4IN9A 3KMCA 4WKEA 4FVLA 3B92A 2X7MA 1QICA 2DDYA 4FXYP 2K2GA 2CLTA 1YCMA 1JAPA 1UMTA 4H82A 1JK3A 4PKTA 1CK7A 1XUCA 4WF6A 3BA0A 2N8RA 3ELMA 5BOTA 1O0QA 3P24A 5D1SA 2I47A 1KUHA 2OVXA 1KBCA 3EDHA 1UTZA 4QKZA 1SLMA 3I7IA 4JIJA 5B5OA 2OXWA 1XFUA 4R3VA 1D8FA 1WNIA 2DDFA 4HMAA 1ZVXA 3F15A 3EDZA 5I4OA 1XFWA 4JPAA 2DW2A 4Q1LA 3LUNA 1HV5A 4AYKA 1DMTA 3SHIA 966CA 1AYKA 2JT6A 2JNPA 1BM6A 1UTTA 1Y0VA 4H1QA 4GF1A 1HFCA 4JA1A 4I03A 1D8MA 1ND1A 1BKCE 3EHXA 4PKRA 1UMSA 4JQGA 1HTDA 3LGPA 3N2UA 3AYUA 4WZVA 4PKVA 1IACA 4FU4A 4PKUA 2W13A 4GWMA 4HX3A 4AUOA 3LJTA 1IABA 5I0LA 3TSKA 3HY9A 5L79A 4G0DA 2OY4A 4A7BA 1SATA 4GR3A 1USNA 5H8XA 1C8TA 1GE6A 2OZRA 3NX7A 1RM8A 3DWBA 1FBLA 3B8ZA 4XM6A 1QJIA 4ILWD 2MZEA 1CXVA 2OY2A 2W12A 4PKQA 3DPEA 3EWJA 3HDBA 3OHLA 1J7NA 3TT4A 4H76A 3K7NA 2OW0A 2X3BA 2RJPA 1UEAA 1JH1A 1GE7A 1SLNA 1OMJA 4CTHA 2MZHA 1Q3AA 1CQRA 1IADA 1JAQA 2QPJA 3CKIA 1D7XA 1ZS0A 2WOAA 3LK8A 5LABA 1S4BP 2MZIA 3O64A 1AKLA 5D7WA 4DPEA 1OM6A 3EDGA 1XFVA 1OO9A 3F16A 1BZSA 3RTTA 1ZP5A 3F18A 1QIAA 2OXZA 3LKAA 1PWUA 3L0VA 2J83A 3LMCA 4ON1A 2FV9A 1IAEA 5D3CA 3GBOA 2OW9A 2XS3A 4JP4A 5CZMA 1GKCA 1R1IA 4IUWA 1EB6A 1DTHA 1R1HA 1MMRA 3F19A 2RJQA 3O2XA 5CUHA 1D5JA 2HU6A 1B8YA 3OHOA 1SU3A 2O3EA 3WV1A 1CGEA 2KRJA 1MMQA 2V4BA 3B2ZA 4XM8A 2X3CA 2AYKA 2SRTA 1BKCI 456CA 1KUGA 3Q2GA 1G4KA 1L6JA 3DSLA 4H49A 5D1TA 1H71P 1EUBA 1HY7A 2W0DA 5CXAA 1Z3JA 3L0TA 2ERQA 1QJJA 2OI0A 3KWVC 2PJTA 1ZXVA 1G12A 3ZUKA 4GUYA 2FV5A 2AIGP 1BQQM 1YOUA 4FXQA 3LUMA 3K7LA 3F17A 3LILA 3KMEA 1BUDA 4PKWA 2X3AA 4WKIA 1PWPA 3KEJA 1G49A 5I43A 2Y6CA 2POJA 1I1IP 3LQ0A 4WK7A 2EROA 1ATLA 1JJ9A 1YP1A 3LEAA 4PKSA 2MLSA 5I2ZA 1MNCA 1GO7P 1G9KA 4AXQA 3DNGA 2K9CA 1QUAA 5D1UA 4A3WA 2Z2DA 1XFYA 1C3IA 1BKCA 1XFZA 3WV2A 1GO8P 2W14A 1B3DA 2A8HA 5I3MA 2DW1A 4J4MA 4I35A 1PWQA 3Q2HA 2E2DA 3ZXHA 1R1JA 5L7FA 2WO9A 4H84A 2WO8A 3VTGA 1KUIA 5BOYA 3USNA 1I76A 4GR8A 1ROSA 4GR0A 1FM1A 2OW2A 3DL1A 3EHYA 1OS2A 2YIGA 5I12A 3E8RA 1MMBA 1CGFA 4L6TA 1SMPA 2Y6DA 3AIGA 3HYGA 1K7GA 4XM7A 5D2BA 1OS9A 4GQLA 4EFSA 4H2EA 4GWNA 3N2VA 1AF0A 1C7KA 3LQBA
chains in the Genus database with same CATH superfamily
4L19A 1JANA 1K7QA 2XS4A 1QIBA 5JMYA 4DV8A 1EAKA 1BIWA 1KUKA 1ZXCA 1Y93A 3I7GA 1OM8A 2ERPA 3P1VA 1K7IA 2JSDA 2L0RA 3LIKA 4XCTA 1G05A 2D1NA 1Y8JA 3HB2P 1XURA 4ZR5A 1SRPA 3DPFA 3ZVSA 2OVZA 2E3XA 1A86A 3LJZA 1O0TA 1JIZA 3AYKA 1BUVM 3HY7A 4IJOA 1IAAA 3G42A 830CA 1GXDA 3HDAP 3V96B 4XBHA 2YB9A 3F1AA 1GKDA 2USNA 2MLRA 3G5CA 1BSWA 2JIHA 1XAXA 3VI1A 1BQOA 3TS4A 2CKIA 3LJGA 3UVCA 2J0TA 2W15A 1KUFA 1JIWP 3LE9A 3HBUP 1FLSA 1JAOA 2OXUA 1R55A 1YQYA 1MMPA 3WV3A 3EDIA 2D1OA 5BPAA 2O36A 1KAPP 1RMZA 1ZTQA 1XFXA 5B5PA 4DD8A 3KECA 3RTSA 3KHIA 3KRYA 4L63A 1XUDA 3U1RA 1CGLA 1CAQA 1HFSA 3KEKA 4DF9A 2OW1A 2TCLA 1PWWA 1R54A 1ASTA 3TVCA 1IAGA 4AIGA 1GE5A 4H3XA 2JT5A 1JKYA 1I73A 4H30A 1PWVA 3MA2A 1A85A 3LIRA 3HBVP 1OM7A 1CIZA 2DW0A 4G9LA 1HOVA 4IN9A 3KMCA 4WKEA 4FVLA 3B92A 2X7MA 1QICA 2DDYA 4FXYP 2K2GA 2CLTA 1YCMA 1JAPA 1UMTA 4H82A 1JK3A 4PKTA 1CK7A 1XUCA 4WF6A 3BA0A 2N8RA 3ELMA 5BOTA 1O0QA 3P24A 5D1SA 2I47A 1KUHA 2OVXA 1KBCA 3EDHA 1UTZA 4QKZA 1SLMA 1TVIA 3I7IA 4JIJA 5B5OA 2OXWA 1XFUA 4R3VA 1D8FA 1WNIA 2DDFA 4HMAA 1ZVXA 3F15A 3EDZA 5I4OA 1XFWA 4JPAA 2DW2A 4Q1LA 3LUNA 1HV5A 4AYKA 1DMTA 3SHIA 966CA 1AYKA 2JT6A 2JNPA 1BM6A 1UTTA 1Y0VA 4H1QA 4GF1A 1HFCA 4JA1A 4I03A 1D8MA 1ND1A 3DTKA 1BKCE 3EHXA 4PKRA 1UMSA 4JQGA 1HTDA 3LGPA 3N2UA 3AYUA 4WZVA 4PKVA 1IACA 4FU4A 4PKUA 2W13A 4GWMA 4HX3A 4AUOA 3LJTA 1IABA 5I0LA 3TSKA 3HY9A 5L79A 4G0DA 2OY4A 4A7BA 1SATA 4GR3A 1USNA 5H8XA 1C8TA 1GE6A 2OZRA 3NX7A 1RM8A 3DWBA 1FBLA 3B8ZA 4XM6A 1QJIA 4ILWD 2MZEA 1CXVA 2OY2A 2W12A 4PKQA 3DPEA 3EWJA 3HDBA 3OHLA 1J7NA 3TT4A 4H76A 3K7NA 4L7AA 2OW0A 2X3BA 2RJPA 1UEAA 1JH1A 1GE7A 3DTIA 1SLNA 2YUFA 1OMJA 4CTHA 2MZHA 1XM5A 1Q3AA 1CQRA 1IADA 1JAQA 2QPJA 3DTEA 3CKIA 1D7XA 1ZS0A 2WOAA 3LK8A 5LABA 1S4BP 2MZIA 3O64A 1AKLA 5D7WA 1OZ9A 4DPEA 1OM6A 3EDGA 1XFVA 1OO9A 3F16A 1BZSA 3RTTA 1ZP5A 3F18A 1QIAA 2OXZA 3LKAA 1PWUA 3L0VA 2J83A 3LMCA 4ON1A 2FV9A 1IAEA 5D3CA 3GBOA 2OW9A 2XS3A 4JP4A 5CZMA 1GKCA 1R1IA 4IUWA 1EB6A 1DTHA 1R1HA 1MMRA 3F19A 2RJQA 3O2XA 5CUHA 1D5JA 2HU6A 1B8YA 3OHOA 1SU3A 2O3EA 3WV1A 1CGEA 2KRJA 1MMQA 2V4BA 3B2ZA 4XM8A 2X3CA 2AYKA 2SRTA 1BKCI 456CA 1KUGA 3Q2GA 1G4KA 1L6JA 3DSLA 4H49A 5D1TA 1H71P 1EUBA 1HY7A 2W0DA 5CXAA 1Z3JA 3L0TA 2ERQA 1QJJA 2OI0A 3KWVC 2PJTA 1ZXVA 1G12A 3ZUKA 4GUYA 2FV5A 2AIGP 1BQQM 1YOUA 4FXQA 3LUMA 3K7LA 3F17A 3LILA 3KMEA 1BUDA 4PKWA 2X3AA 4WKIA 1PWPA 3KEJA 1G49A 5I43A 2Y6CA 2POJA 1I1IP 3LQ0A 4WK7A 2EROA 1ATLA 1JJ9A 1YP1A 3LEAA 4PKSA 2MLSA 5I2ZA 1MNCA 1GO7P 1G9KA 4AXQA 3DNGA 2K9CA 1QUAA 5D1UA 4A3WA 2Z2DA 1XFYA 1C3IA 1BKCA 1XFZA 3WV2A 1GO8P 2W14A 1B3DA 2A8HA 5I3MA 2DW1A 4J4MA 4I35A 1PWQA 3Q2HA 2E2DA 3ZXHA 1R1JA 5L7FA 2WO9A 4H84A 2WO8A 3VTGA 1KUIA 5BOYA 3USNA 1I76A 4GR8A 1ROSA 4GR0A 1FM1A 2OW2A 3DL1A 3EHYA 1OS2A 2YIGA 5I12A 3E8RA 1MMBA 1CGFA 4L6TA 1SMPA 2Y6DA 3AIGA 3HYGA 1K7GA 4XM7A 5D2BA 1OS9A 4GQLA 4EFSA 4H2EA 4GWNA 3N2VA 1AF0A 1C7KA 3LQBA
chains in the Genus database with same CATH topology
4L19A 1JANA 1K7QA 2XS4A 1QIBA 5JMYA 4DV8A 1EAKA 1BIWA 1KUKA 1ZXCA 1Y93A 3I7GA 1OM8A 2ERPA 3P1VA 1K7IA 2JSDA 2L0RA 3LIKA 4XCTA 1G05A 2D1NA 1Y8JA 3HB2P 1XURA 4ZR5A 1SRPA 3DPFA 3ZVSA 2OVZA 2E3XA 1A86A 3LJZA 1O0TA 1JIZA 3AYKA 1BUVM 3HY7A 4IJOA 1IAAA 3G42A 830CA 1GXDA 3HDAP 3V96B 4XBHA 2YB9A 3F1AA 1GKDA 2USNA 2MLRA 3G5CA 1BSWA 2JIHA 3VI1A 1BQOA 3TS4A 2CKIA 3LJGA 3UVCA 2J0TA 2W15A 1KUFA 1JIWP 3LE9A 3HBUP 1FLSA 1JAOA 2OXUA 1R55A 1YQYA 1MMPA 3WV3A 3EDIA 2D1OA 5BPAA 2O36A 1KAPP 1RMZA 1ZTQA 1XFXA 5B5PA 4DD8A 3KECA 3RTSA 3KHIA 3KRYA 4L63A 1XUDA 3U1RA 1CGLA 1CAQA 1HFSA 3KEKA 4DF9A 2OW1A 2TCLA 1PWWA 1R54A 1ASTA 3TVCA 1IAGA 4AIGA 1GE5A 4H3XA 2JT5A 1JKYA 1I73A 4H30A 1PWVA 3MA2A 1A85A 3LIRA 3HBVP 1OM7A 1CIZA 2DW0A 4G9LA 1HOVA 4IN9A 3KMCA 4WKEA 4FVLA 3B92A 2X7MA 1QICA 2DDYA 4FXYP 2K2GA 2CLTA 1YCMA 1JAPA 1UMTA 4H82A 1JK3A 4PKTA 1CK7A 1XUCA 4WF6A 3BA0A 2N8RA 3ELMA 5BOTA 1O0QA 3P24A 5D1SA 2I47A 1KUHA 2OVXA 1KBCA 3EDHA 1UTZA 4QKZA 1SLMA 3I7IA 4JIJA 5B5OA 2OXWA 1XFUA 4R3VA 1D8FA 1WNIA 2DDFA 4HMAA 1ZVXA 3F15A 3EDZA 5I4OA 1XFWA 4JPAA 2DW2A 4Q1LA 3LUNA 1HV5A 4AYKA 1DMTA 3SHIA 966CA 1AYKA 2JT6A 2JNPA 1BM6A 1UTTA 1Y0VA 4H1QA 4GF1A 1HFCA 4JA1A 4I03A 1D8MA 1ND1A 3DTKA 1BKCE 3EHXA 4PKRA 1UMSA 4JQGA 1HTDA 3LGPA 3N2UA 3AYUA 4WZVA 4PKVA 1IACA 4FU4A 4PKUA 2W13A 4GWMA 4HX3A 4AUOA 3LJTA 1IABA 5I0LA 3TSKA 3HY9A 5L79A 4G0DA 2OY4A 4A7BA 1SATA 4GR3A 1USNA 5H8XA 1C8TA 1GE6A 2OZRA 3NX7A 1RM8A 3DWBA 1FBLA 3B8ZA 4XM6A 1QJIA 4ILWD 2MZEA 1CXVA 2OY2A 2W12A 4PKQA 3DPEA 3EWJA 3HDBA 3OHLA 1J7NA 3TT4A 4H76A 3K7NA 4L7AA 2OW0A 2X3BA 2RJPA 1UEAA 1JH1A 1GE7A 3DTIA 1SLNA 2YUFA 1OMJA 4CTHA 2MZHA 1Q3AA 1CQRA 1IADA 1JAQA 2QPJA 3DTEA 3CKIA 1D7XA 1ZS0A 2WOAA 3LK8A 5LABA 1S4BP 2MZIA 3O64A 1AKLA 5D7WA 4DPEA 1OM6A 3EDGA 1XFVA 1OO9A 3F16A 1BZSA 3RTTA 1ZP5A 3F18A 1QIAA 2OXZA 3LKAA 1PWUA 3L0VA 2J83A 3LMCA 4ON1A 2FV9A 1IAEA 5D3CA 3GBOA 2OW9A 2XS3A 4JP4A 5CZMA 1GKCA 1R1IA 4IUWA 1EB6A 1DTHA 1R1HA 1MMRA 3F19A 2RJQA 3O2XA 5CUHA 1D5JA 2HU6A 1B8YA 3OHOA 1SU3A 2O3EA 3WV1A 1CGEA 2KRJA 1MMQA 2V4BA 3B2ZA 4XM8A 2X3CA 2AYKA 2SRTA 1BKCI 456CA 1KUGA 3Q2GA 1G4KA 1L6JA 3DSLA 4H49A 5D1TA 1H71P 1EUBA 1HY7A 2W0DA 5CXAA 1Z3JA 3L0TA 2ERQA 1QJJA 2OI0A 3KWVC 2PJTA 1ZXVA 1G12A 3ZUKA 4GUYA 2FV5A 2AIGP 1BQQM 1YOUA 4FXQA 3LUMA 3K7LA 3F17A 3LILA 3KMEA 1BUDA 4PKWA 2X3AA 4WKIA 1PWPA 3KEJA 1G49A 5I43A 2Y6CA 2POJA 1I1IP 3LQ0A 4WK7A 2EROA 1ATLA 1JJ9A 1YP1A 3LEAA 4PKSA 2MLSA 5I2ZA 1MNCA 1GO7P 1G9KA 4AXQA 3DNGA 2K9CA 1QUAA 5D1UA 4A3WA 2Z2DA 1XFYA 1C3IA 1BKCA 1XFZA 3WV2A 1GO8P 2W14A 1B3DA 2A8HA 5I3MA 2DW1A 4J4MA 4I35A 1PWQA 3Q2HA 2E2DA 3ZXHA 1R1JA 5L7FA 2WO9A 4H84A 2WO8A 3VTGA 1KUIA 5BOYA 3USNA 1I76A 4GR8A 1ROSA 4GR0A 1FM1A 2OW2A 3DL1A 3EHYA 1OS2A 2YIGA 5I12A 3E8RA 1MMBA 1CGFA 4L6TA 1SMPA 2Y6DA 3AIGA 3HYGA 1K7GA 4XM7A 5D2BA 1OS9A 4GQLA 4EFSA 4H2EA 4GWNA 3N2VA 1AF0A 1C7KA 3LQBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4L19 A;  1JAN A;  1K7Q A;  2XS4 A;  1QIB A;  5JMY A;  4DV8 A;  1EAK A;  1BIW A;  1KUK A;  1ZXC A;  1Y93 A;  3I7G A;  1OM8 A;  2ERP A;  3P1V A;  1K7I A;  2JSD A;  2L0R A;  3LIK A;  4XCT A;  1G05 A;  2D1N A;  1Y8J A;  3HB2 P;  1XUR A;  4ZR5 A;  1SRP A;  3DPF A;  3ZVS A;  2OVZ A;  2E3X A;  1A86 A;  3LJZ A;  1O0T A;  1JIZ A;  3AYK A;  1BUV M;  3HY7 A;  4IJO A;  1IAA A;  3G42 A;  830C A;  1GXD A;  3HDA P;  3V96 B;  4XBH A;  2YB9 A;  3F1A A;  1GKD A;  2USN A;  2MLR A;  3G5C A;  1BSW A;  2JIH A;  3VI1 A;  1BQO A;  3TS4 A;  2CKI A;  3LJG A;  3UVC A;  2J0T A;  2W15 A;  1KUF A;  1JIW P;  3LE9 A;  3HBU P;  1FLS A;  1JAO A;  2OXU A;  1R55 A;  1YQY A;  1MMP A;  3WV3 A;  3EDI A;  2D1O A;  5BPA A;  2O36 A;  1KAP P;  1RMZ A;  1ZTQ A;  1XFX A;  5B5P A;  4DD8 A;  3KEC A;  3RTS A;  3KHI A;  3KRY A;  4L63 A;  1XUD A;  3U1R A;  1CGL A;  1CAQ A;  1HFS A;  3KEK A;  4DF9 A;  2OW1 A;  2TCL A;  1PWW A;  1R54 A;  1AST A;  3TVC A;  1IAG A;  4AIG A;  1GE5 A;  4H3X A;  2JT5 A;  1JKY A;  1I73 A;  4H30 A;  1PWV A;  3MA2 A;  1A85 A;  3LIR A;  3HBV P;  1OM7 A;  1CIZ A;  2DW0 A;  4G9L A;  1HOV A;  4IN9 A;  3KMC A;  4WKE A;  4FVL A;  3B92 A;  2X7M A;  1QIC A;  2DDY A;  4FXY P;  2K2G A;  2CLT A;  1YCM A;  1JAP A;  1UMT A;  4H82 A;  1JK3 A;  4PKT A;  1CK7 A;  1XUC A;  4WF6 A;  3BA0 A;  2N8R A;  3ELM A;  5BOT A;  1O0Q A;  3P24 A;  5D1S A;  2I47 A;  1KUH A;  2OVX A;  1KBC A;  3EDH A;  1UTZ A;  4QKZ A;  1SLM A;  3I7I A;  4JIJ A;  5B5O A;  2OXW A;  1XFU A;  4R3V A;  1D8F A;  1WNI A;  2DDF A;  4HMA A;  1ZVX A;  3F15 A;  3EDZ A;  5I4O A;  1XFW A;  4JPA A;  2DW2 A;  4Q1L A;  3LUN A;  1HV5 A;  4AYK A;  1DMT A;  3SHI A;  966C A;  1AYK A;  2JT6 A;  2JNP A;  1BM6 A;  1UTT A;  1Y0V A;  4H1Q A;  4GF1 A;  1HFC A;  4JA1 A;  4I03 A;  1D8M A;  1ND1 A;  1BKC E;  3EHX A;  4PKR A;  1UMS A;  4JQG A;  1HTD A;  3LGP A;  3N2U A;  3AYU A;  4WZV A;  4PKV A;  1IAC A;  4FU4 A;  4PKU A;  2W13 A;  4GWM A;  4HX3 A;  4AUO A;  3LJT A;  1IAB A;  5I0L A;  3TSK A;  3HY9 A;  5L79 A;  4G0D A;  2OY4 A;  4A7B A;  1SAT A;  4GR3 A;  1USN A;  5H8X A;  1C8T A;  1GE6 A;  2OZR A;  3NX7 A;  1RM8 A;  3DWB A;  1FBL A;  3B8Z A;  4XM6 A;  1QJI A;  4ILW D;  2MZE A;  1CXV A;  2OY2 A;  2W12 A;  4PKQ A;  3DPE A;  3EWJ A;  3HDB A;  3OHL A;  1J7N A;  3TT4 A;  4H76 A;  3K7N A;  2OW0 A;  2X3B A;  2RJP A;  1UEA A;  1JH1 A;  1GE7 A;  1SLN A;  1OMJ A;  4CTH A;  2MZH A;  1Q3A A;  1CQR A;  1IAD A;  1JAQ A;  2QPJ A;  3CKI A;  1D7X A;  1ZS0 A;  2WOA A;  3LK8 A;  5LAB A;  1S4B P;  2MZI A;  3O64 A;  1AKL A;  5D7W A;  4DPE A;  1OM6 A;  3EDG A;  1XFV A;  1OO9 A;  3F16 A;  1BZS A;  3RTT A;  1ZP5 A;  3F18 A;  1QIA A;  2OXZ A;  3LKA A;  1PWU A;  3L0V A;  2J83 A;  3LMC A;  4ON1 A;  2FV9 A;  1IAE A;  5D3C A;  3GBO A;  2OW9 A;  2XS3 A;  4JP4 A;  5CZM A;  1GKC A;  1R1I A;  4IUW A;  1EB6 A;  1DTH A;  1R1H A;  1MMR A;  3F19 A;  2RJQ A;  3O2X A;  5CUH A;  1D5J A;  2HU6 A;  1B8Y A;  3OHO A;  1SU3 A;  2O3E A;  3WV1 A;  1CGE A;  2KRJ A;  1MMQ A;  2V4B A;  3B2Z A;  4XM8 A;  2X3C A;  2AYK A;  2SRT A;  1BKC I;  456C A;  1KUG A;  3Q2G A;  1G4K A;  1L6J A;  3DSL A;  4H49 A;  5D1T A;  1H71 P;  1EUB A;  1HY7 A;  2W0D A;  5CXA A;  1Z3J A;  3L0T A;  2ERQ A;  1QJJ A;  2OI0 A;  3KWV C;  2PJT A;  1ZXV A;  1G12 A;  3ZUK A;  4GUY A;  2FV5 A;  2AIG P;  1BQQ M;  1YOU A;  4FXQ A;  3LUM A;  3K7L A;  3F17 A;  3LIL A;  3KME A;  1BUD A;  4PKW A;  2X3A A;  4WKI A;  1PWP A;  3KEJ A;  1G49 A;  5I43 A;  2Y6C A;  2POJ A;  1I1I P;  3LQ0 A;  4WK7 A;  2ERO A;  1ATL A;  1JJ9 A;  1YP1 A;  3LEA A;  4PKS A;  2MLS A;  5I2Z A;  1MNC A;  1GO7 P;  1G9K A;  4AXQ A;  3DNG A;  2K9C A;  1QUA A;  5D1U A;  4A3W A;  2Z2D A;  1XFY A;  1C3I A;  1BKC A;  1XFZ A;  3WV2 A;  1GO8 P;  2W14 A;  1B3D A;  2A8H A;  5I3M A;  2DW1 A;  4J4M A;  4I35 A;  1PWQ A;  3Q2H A;  2E2D A;  3ZXH A;  1R1J A;  5L7F A;  2WO9 A;  4H84 A;  2WO8 A;  3VTG A;  1KUI A;  5BOY A;  3USN A;  1I76 A;  4GR8 A;  1ROS A;  4GR0 A;  1FM1 A;  2OW2 A;  3DL1 A;  3EHY A;  1OS2 A;  2YIG A;  5I12 A;  3E8R A;  1MMB A;  1CGF A;  4L6T A;  1SMP A;  2Y6D A;  3AIG A;  3HYG A;  1K7G A;  4XM7 A;  5D2B A;  1OS9 A;  4GQL A;  4EFS A;  4H2E A;  4GWN A;  3N2V A;  1AF0 A;  1C7K A;  3LQB A; 
#chains in the Genus database with same CATH topology
 4L19 A;  1JAN A;  1K7Q A;  2XS4 A;  1QIB A;  5JMY A;  4DV8 A;  1EAK A;  1BIW A;  1KUK A;  1ZXC A;  1Y93 A;  3I7G A;  1OM8 A;  2ERP A;  3P1V A;  1K7I A;  2JSD A;  2L0R A;  3LIK A;  4XCT A;  1G05 A;  2D1N A;  1Y8J A;  3HB2 P;  1XUR A;  4ZR5 A;  1SRP A;  3DPF A;  3ZVS A;  2OVZ A;  2E3X A;  1A86 A;  3LJZ A;  1O0T A;  1JIZ A;  3AYK A;  1BUV M;  3HY7 A;  4IJO A;  1IAA A;  3G42 A;  830C A;  1GXD A;  3HDA P;  3V96 B;  4XBH A;  2YB9 A;  3F1A A;  1GKD A;  2USN A;  2MLR A;  3G5C A;  1BSW A;  2JIH A;  1XAX A;  3VI1 A;  1BQO A;  3TS4 A;  2CKI A;  3LJG A;  3UVC A;  2J0T A;  2W15 A;  1KUF A;  1JIW P;  3LE9 A;  3HBU P;  1FLS A;  1JAO A;  2OXU A;  1R55 A;  1YQY A;  1MMP A;  3WV3 A;  3EDI A;  2D1O A;  5BPA A;  2O36 A;  1KAP P;  1RMZ A;  1ZTQ A;  1XFX A;  5B5P A;  4DD8 A;  3KEC A;  3RTS A;  3KHI A;  3KRY A;  4L63 A;  1XUD A;  3U1R A;  1CGL A;  1CAQ A;  1HFS A;  3KEK A;  4DF9 A;  2OW1 A;  2TCL A;  1PWW A;  1R54 A;  1AST A;  3TVC A;  1IAG A;  4AIG A;  1GE5 A;  4H3X A;  2JT5 A;  1JKY A;  1I73 A;  4H30 A;  1PWV A;  3MA2 A;  1A85 A;  3LIR A;  3HBV P;  1OM7 A;  1CIZ A;  2DW0 A;  4G9L A;  1HOV A;  4IN9 A;  3KMC A;  4WKE A;  4FVL A;  3B92 A;  2X7M A;  1QIC A;  2DDY A;  4FXY P;  2K2G A;  2CLT A;  1YCM A;  1JAP A;  1UMT A;  4H82 A;  1JK3 A;  4PKT A;  1CK7 A;  1XUC A;  4WF6 A;  3BA0 A;  2N8R A;  3ELM A;  5BOT A;  1O0Q A;  3P24 A;  5D1S A;  2I47 A;  1KUH A;  2OVX A;  1KBC A;  3EDH A;  1UTZ A;  4QKZ A;  1SLM A;  1TVI A;  3I7I A;  4JIJ A;  5B5O A;  2OXW A;  1XFU A;  4R3V A;  1D8F A;  1WNI A;  2DDF A;  4HMA A;  1ZVX A;  3F15 A;  3EDZ A;  5I4O A;  1XFW A;  4JPA A;  2DW2 A;  4Q1L A;  3LUN A;  1HV5 A;  4AYK A;  1DMT A;  3SHI A;  966C A;  1AYK A;  2JT6 A;  2JNP A;  1BM6 A;  1UTT A;  1Y0V A;  4H1Q A;  4GF1 A;  1HFC A;  4JA1 A;  4I03 A;  1D8M A;  1ND1 A;  3DTK A;  1BKC E;  3EHX A;  4PKR A;  1UMS A;  4JQG A;  1HTD A;  3LGP A;  3N2U A;  3AYU A;  4WZV A;  4PKV A;  1IAC A;  4FU4 A;  4PKU A;  2W13 A;  4GWM A;  4HX3 A;  4AUO A;  3LJT A;  1IAB A;  5I0L A;  3TSK A;  3HY9 A;  5L79 A;  4G0D A;  2OY4 A;  4A7B A;  1SAT A;  4GR3 A;  1USN A;  5H8X A;  1C8T A;  1GE6 A;  2OZR A;  3NX7 A;  1RM8 A;  3DWB A;  1FBL A;  3B8Z A;  4XM6 A;  1QJI A;  4ILW D;  2MZE A;  1CXV A;  2OY2 A;  2W12 A;  4PKQ A;  3DPE A;  3EWJ A;  3HDB A;  3OHL A;  1J7N A;  3TT4 A;  4H76 A;  3K7N A;  4L7A A;  2OW0 A;  2X3B A;  2RJP A;  1UEA A;  1JH1 A;  1GE7 A;  3DTI A;  1SLN A;  2YUF A;  1OMJ A;  4CTH A;  2MZH A;  1XM5 A;  1Q3A A;  1CQR A;  1IAD A;  1JAQ A;  2QPJ A;  3DTE A;  3CKI A;  1D7X A;  1ZS0 A;  2WOA A;  3LK8 A;  5LAB A;  1S4B P;  2MZI A;  3O64 A;  1AKL A;  5D7W A;  1OZ9 A;  4DPE A;  1OM6 A;  3EDG A;  1XFV A;  1OO9 A;  3F16 A;  1BZS A;  3RTT A;  1ZP5 A;  3F18 A;  1QIA A;  2OXZ A;  3LKA A;  1PWU A;  3L0V A;  2J83 A;  3LMC A;  4ON1 A;  2FV9 A;  1IAE A;  5D3C A;  3GBO A;  2OW9 A;  2XS3 A;  4JP4 A;  5CZM A;  1GKC A;  1R1I A;  4IUW A;  1EB6 A;  1DTH A;  1R1H A;  1MMR A;  3F19 A;  2RJQ A;  3O2X A;  5CUH A;  1D5J A;  2HU6 A;  1B8Y A;  3OHO A;  1SU3 A;  2O3E A;  3WV1 A;  1CGE A;  2KRJ A;  1MMQ A;  2V4B A;  3B2Z A;  4XM8 A;  2X3C A;  2AYK A;  2SRT A;  1BKC I;  456C A;  1KUG A;  3Q2G A;  1G4K A;  1L6J A;  3DSL A;  4H49 A;  5D1T A;  1H71 P;  1EUB A;  1HY7 A;  2W0D A;  5CXA A;  1Z3J A;  3L0T A;  2ERQ A;  1QJJ A;  2OI0 A;  3KWV C;  2PJT A;  1ZXV A;  1G12 A;  3ZUK A;  4GUY A;  2FV5 A;  2AIG P;  1BQQ M;  1YOU A;  4FXQ A;  3LUM A;  3K7L A;  3F17 A;  3LIL A;  3KME A;  1BUD A;  4PKW A;  2X3A A;  4WKI A;  1PWP A;  3KEJ A;  1G49 A;  5I43 A;  2Y6C A;  2POJ A;  1I1I P;  3LQ0 A;  4WK7 A;  2ERO A;  1ATL A;  1JJ9 A;  1YP1 A;  3LEA A;  4PKS A;  2MLS A;  5I2Z A;  1MNC A;  1GO7 P;  1G9K A;  4AXQ A;  3DNG A;  2K9C A;  1QUA A;  5D1U A;  4A3W A;  2Z2D A;  1XFY A;  1C3I A;  1BKC A;  1XFZ A;  3WV2 A;  1GO8 P;  2W14 A;  1B3D A;  2A8H A;  5I3M A;  2DW1 A;  4J4M A;  4I35 A;  1PWQ A;  3Q2H A;  2E2D A;  3ZXH A;  1R1J A;  5L7F A;  2WO9 A;  4H84 A;  2WO8 A;  3VTG A;  1KUI A;  5BOY A;  3USN A;  1I76 A;  4GR8 A;  1ROS A;  4GR0 A;  1FM1 A;  2OW2 A;  3DL1 A;  3EHY A;  1OS2 A;  2YIG A;  5I12 A;  3E8R A;  1MMB A;  1CGF A;  4L6T A;  1SMP A;  2Y6D A;  3AIG A;  3HYG A;  1K7G A;  4XM7 A;  5D2B A;  1OS9 A;  4GQL A;  4EFS A;  4H2E A;  4GWN A;  3N2V A;  1AF0 A;  1C7K A;  3LQB A; 
#chains in the Genus database with same CATH homology
 4L19 A;  1JAN A;  1K7Q A;  2XS4 A;  1QIB A;  5JMY A;  4DV8 A;  1EAK A;  1BIW A;  1KUK A;  1ZXC A;  1Y93 A;  3I7G A;  1OM8 A;  2ERP A;  3P1V A;  1K7I A;  2JSD A;  2L0R A;  3LIK A;  4XCT A;  1G05 A;  2D1N A;  1Y8J A;  3HB2 P;  1XUR A;  4ZR5 A;  1SRP A;  3DPF A;  3ZVS A;  2OVZ A;  2E3X A;  1A86 A;  3LJZ A;  1O0T A;  1JIZ A;  3AYK A;  1BUV M;  3HY7 A;  4IJO A;  1IAA A;  3G42 A;  830C A;  1GXD A;  3HDA P;  3V96 B;  4XBH A;  2YB9 A;  3F1A A;  1GKD A;  2USN A;  2MLR A;  3G5C A;  1BSW A;  2JIH A;  3VI1 A;  1BQO A;  3TS4 A;  2CKI A;  3LJG A;  3UVC A;  2J0T A;  2W15 A;  1KUF A;  1JIW P;  3LE9 A;  3HBU P;  1FLS A;  1JAO A;  2OXU A;  1R55 A;  1YQY A;  1MMP A;  3WV3 A;  3EDI A;  2D1O A;  5BPA A;  2O36 A;  1KAP P;  1RMZ A;  1ZTQ A;  1XFX A;  5B5P A;  4DD8 A;  3KEC A;  3RTS A;  3KHI A;  3KRY A;  4L63 A;  1XUD A;  3U1R A;  1CGL A;  1CAQ A;  1HFS A;  3KEK A;  4DF9 A;  2OW1 A;  2TCL A;  1PWW A;  1R54 A;  1AST A;  3TVC A;  1IAG A;  4AIG A;  1GE5 A;  4H3X A;  2JT5 A;  1JKY A;  1I73 A;  4H30 A;  1PWV A;  3MA2 A;  1A85 A;  3LIR A;  3HBV P;  1OM7 A;  1CIZ A;  2DW0 A;  4G9L A;  1HOV A;  4IN9 A;  3KMC A;  4WKE A;  4FVL A;  3B92 A;  2X7M A;  1QIC A;  2DDY A;  4FXY P;  2K2G A;  2CLT A;  1YCM A;  1JAP A;  1UMT A;  4H82 A;  1JK3 A;  4PKT A;  1CK7 A;  1XUC A;  4WF6 A;  3BA0 A;  2N8R A;  3ELM A;  5BOT A;  1O0Q A;  3P24 A;  5D1S A;  2I47 A;  1KUH A;  2OVX A;  1KBC A;  3EDH A;  1UTZ A;  4QKZ A;  1SLM A;  3I7I A;  4JIJ A;  5B5O A;  2OXW A;  1XFU A;  4R3V A;  1D8F A;  1WNI A;  2DDF A;  4HMA A;  1ZVX A;  3F15 A;  3EDZ A;  5I4O A;  1XFW A;  4JPA A;  2DW2 A;  4Q1L A;  3LUN A;  1HV5 A;  4AYK A;  1DMT A;  3SHI A;  966C A;  1AYK A;  2JT6 A;  2JNP A;  1BM6 A;  1UTT A;  1Y0V A;  4H1Q A;  4GF1 A;  1HFC A;  4JA1 A;  4I03 A;  1D8M A;  1ND1 A;  3DTK A;  1BKC E;  3EHX A;  4PKR A;  1UMS A;  4JQG A;  1HTD A;  3LGP A;  3N2U A;  3AYU A;  4WZV A;  4PKV A;  1IAC A;  4FU4 A;  4PKU A;  2W13 A;  4GWM A;  4HX3 A;  4AUO A;  3LJT A;  1IAB A;  5I0L A;  3TSK A;  3HY9 A;  5L79 A;  4G0D A;  2OY4 A;  4A7B A;  1SAT A;  4GR3 A;  1USN A;  5H8X A;  1C8T A;  1GE6 A;  2OZR A;  3NX7 A;  1RM8 A;  3DWB A;  1FBL A;  3B8Z A;  4XM6 A;  1QJI A;  4ILW D;  2MZE A;  1CXV A;  2OY2 A;  2W12 A;  4PKQ A;  3DPE A;  3EWJ A;  3HDB A;  3OHL A;  1J7N A;  3TT4 A;  4H76 A;  3K7N A;  4L7A A;  2OW0 A;  2X3B A;  2RJP A;  1UEA A;  1JH1 A;  1GE7 A;  3DTI A;  1SLN A;  2YUF A;  1OMJ A;  4CTH A;  2MZH A;  1Q3A A;  1CQR A;  1IAD A;  1JAQ A;  2QPJ A;  3DTE A;  3CKI A;  1D7X A;  1ZS0 A;  2WOA A;  3LK8 A;  5LAB A;  1S4B P;  2MZI A;  3O64 A;  1AKL A;  5D7W A;  4DPE A;  1OM6 A;  3EDG A;  1XFV A;  1OO9 A;  3F16 A;  1BZS A;  3RTT A;  1ZP5 A;  3F18 A;  1QIA A;  2OXZ A;  3LKA A;  1PWU A;  3L0V A;  2J83 A;  3LMC A;  4ON1 A;  2FV9 A;  1IAE A;  5D3C A;  3GBO A;  2OW9 A;  2XS3 A;  4JP4 A;  5CZM A;  1GKC A;  1R1I A;  4IUW A;  1EB6 A;  1DTH A;  1R1H A;  1MMR A;  3F19 A;  2RJQ A;  3O2X A;  5CUH A;  1D5J A;  2HU6 A;  1B8Y A;  3OHO A;  1SU3 A;  2O3E A;  3WV1 A;  1CGE A;  2KRJ A;  1MMQ A;  2V4B A;  3B2Z A;  4XM8 A;  2X3C A;  2AYK A;  2SRT A;  1BKC I;  456C A;  1KUG A;  3Q2G A;  1G4K A;  1L6J A;  3DSL A;  4H49 A;  5D1T A;  1H71 P;  1EUB A;  1HY7 A;  2W0D A;  5CXA A;  1Z3J A;  3L0T A;  2ERQ A;  1QJJ A;  2OI0 A;  3KWV C;  2PJT A;  1ZXV A;  1G12 A;  3ZUK A;  4GUY A;  2FV5 A;  2AIG P;  1BQQ M;  1YOU A;  4FXQ A;  3LUM A;  3K7L A;  3F17 A;  3LIL A;  3KME A;  1BUD A;  4PKW A;  2X3A A;  4WKI A;  1PWP A;  3KEJ A;  1G49 A;  5I43 A;  2Y6C A;  2POJ A;  1I1I P;  3LQ0 A;  4WK7 A;  2ERO A;  1ATL A;  1JJ9 A;  1YP1 A;  3LEA A;  4PKS A;  2MLS A;  5I2Z A;  1MNC A;  1GO7 P;  1G9K A;  4AXQ A;  3DNG A;  2K9C A;  1QUA A;  5D1U A;  4A3W A;  2Z2D A;  1XFY A;  1C3I A;  1BKC A;  1XFZ A;  3WV2 A;  1GO8 P;  2W14 A;  1B3D A;  2A8H A;  5I3M A;  2DW1 A;  4J4M A;  4I35 A;  1PWQ A;  3Q2H A;  2E2D A;  3ZXH A;  1R1J A;  5L7F A;  2WO9 A;  4H84 A;  2WO8 A;  3VTG A;  1KUI A;  5BOY A;  3USN A;  1I76 A;  4GR8 A;  1ROS A;  4GR0 A;  1FM1 A;  2OW2 A;  3DL1 A;  3EHY A;  1OS2 A;  2YIG A;  5I12 A;  3E8R A;  1MMB A;  1CGF A;  4L6T A;  1SMP A;  2Y6D A;  3AIG A;  3HYG A;  1K7G A;  4XM7 A;  5D2B A;  1OS9 A;  4GQL A;  4EFS A;  4H2E A;  4GWN A;  3N2V A;  1AF0 A;  1C7K A;  3LQB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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