4IJOA

Unraveling hidden allosteric regulatory sites in structurally homologues metalloproteases
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
158
structure length
158
Chain Sequence
GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Unraveling hidden regulatory sites in structurally homologous metalloproteases
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Macrophage metalloelastase
total genus 44
structure length 158
sequence length 158
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2012-12-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 4ijoA00
1QJIA 3DWBA 3KRYA 2POJA 3LGPA 3HY7A 1EAKA 1KBCA 2X3AA 3U1RA 2DDFA 456CA 5I2ZA 3F15A 4ON1A 1K7IA 4PKTA 1C7KA 1JAOA 4DPEA 5H8XA 1KUKA 1Q3AA 4GQLA 2J83A 4PKUA 4H82A 1GO7P 1QJJA 1OM8A 1SRPA 2OXWA 3F17A 3TS4A 2FV9A 4GR0A 2J0TA 4H84A 5D1SA 1UEAA 1BKCA 3WV1A 4GWMA 3VI1A 1XUCA 2MZIA 1GKDA 1MMRA 2ERQA 1I76A 3GBOA 1AYKA 3N2UA 3LIKA 3DPFA 3P1VA 4I35A 5B5PA 1SLNA 1BM6A 1GXDA 4XM8A 1JH1A 3EHXA 5CUHA 1BSWA 2OY4A 5BOYA 1IABA 4JP4A 4XBHA 2OVZA 4IN9A 1ND1A 2I47A 4G0DA 4PKQA 1D7XA 1JAPA 3HYGA 4AUOA 3DPEA 3F18A 1XUDA 1ASTA 2SRTA 1YCMA 3UVCA 1OS2A 2OW9A 1GE5A 3KECA 1SLMA 1XFVA 4JIJA 2OZRA 1HV5A 3SHIA 3LK8A 4DF9A 1R1HA 4XM6A 4QKZA 1XURA 1CK7A 1G05A 2W13A 3ELMA 2DW1A 1ZP5A 2MZHA 1PWVA 3EHYA 3WV3A 4A7BA 1H71P 1HFSA 2OXZA 2WOAA 1OS9A 3USNA 3N2VA 5CZMA 1BUVM 2WO8A 1FM1A 3DL1A 3L0TA 4PKVA 2N8RA 1Z3JA 2AYKA 2OI0A 3I7IA 4GWNA 2K9CA 1ZTQA 1ZXVA 2JSDA 1ATLA 2OW2A 1SU3A 1O0TA 2JT5A 4WKIA 4PKWA 4G9LA 1I1IP 2K2GA 3LIRA 5D3CA 2X3CA 4JPAA 1Y93A 1RMZA 1AF0A 1BZSA 5D1UA 4XM7A 5LABA 5I0LA 4AXQA 3LUNA 3EDGA 1WNIA 3KMCA 5CXAA 3EDIA 2Y6DA 3ZVSA 5L79A 1DTHA 2TCLA 2MZEA 2W0DA 1FLSA 1MMQA 1PWWA 2ERPA 2KRJA 1JIZA 3F16A 4H30A 3G42A 1BQOA 1B8YA 1MMBA 1RM8A 1K7QA 5I4OA 2FV5A 1IAEA 1AKLA 4I03A 5JMYA 1D8MA 2USNA 2JT6A 3DNGA 3LE9A 2OY2A 4AIGA 1XFYA 4L63A 3F1AA 3NX7A 4R3VA 4XCTA 2DW0A 3RTTA 1JJ9A 3EWJA 4GR3A 4Q1LA 3LKAA 4ILWD 3LUMA 3B2ZA 1PWQA 3HBUP 3B92A 3OHOA 3G5CA 1HFCA 3LEAA 2JNPA 3BA0A 1GE7A 1GE6A 4H76A 1G49A 4FXYP 1YP1A 1QIBA 2WO9A 1XFWA 2A8HA 1ZVXA 4GUYA 1CAQA 2YB9A 1CGFA 1D5JA 4GR8A 1UTZA 2O3EA 1C8TA 4IUWA 4H3XA 4HMAA 1R1IA 1R55A 3LJTA 2Y6CA 4J4MA 4FU4A 3Q2GA 4L19A 1CGEA 4DD8A 4EFSA 3I7GA 4A3WA 1IAGA 3CKIA 830CA 5I3MA 1B3DA 3TVCA 3HB2P 1Y0VA 3AIGA 1A86A 1S4BP 5I12A 4WKEA 1I73A 5L7FA 1EUBA 2EROA 3AYUA 2OVXA 1UMTA 5B5OA 1JAQA 2D1NA 2RJQA 1ZS0A 5D2BA 3KEKA 1KAPP 3O2XA 1HY7A 2DDYA 4PKRA 4H1QA 1BKCI 3F19A 3LJZA 3TSKA 3LILA 3WV2A 1FBLA 1OO9A 1R1JA 3LQ0A 1G4KA 1OM6A 3KMEA 2OW1A 5BOTA 4L6TA 1QICA 1SATA 3L0VA 1MMPA 1KUIA 2OXUA 1CQRA 3EDZA 2E2DA 1BQQM 1PWPA 1J7NA 4PKSA 4WK7A 1XFZA 4H49A 1XFUA 2JIHA 1USNA 3OHLA 4FXQA 2CLTA 1IADA 1MNCA 1QIAA 1R54A 1KUHA 3AYKA 1JANA 4CTHA 2PJTA 1QUAA 2Z2DA 2X3BA 1YQYA 3HY9A 1CIZA 3LMCA 3HBVP 1HTDA 1CGLA 1OMJA 2AIGP 3K7LA 3DSLA 1PWUA 1GO8P 4GF1A 1A85A 1UTTA 1ZXCA 1JIWP 1L6JA 2E3XA 3MA2A 1JK3A 2YIGA 2W15A 2MLRA 4JA1A 3O64A 5D7WA 4WZVA 2O36A 1YOUA 3Q2HA 3B8ZA 1G12A 4AYKA 3HDBA 3E8RA 1IAAA 4IJOA 1O0QA 2HU6A 3RTSA 2OW0A 2XS3A 2CKIA 1JKYA 3V96B 4H2EA 3ZUKA 3ZXHA 2W14A 2L0RA 4DV8A 1G9KA 1CXVA 1D8FA 966CA 1UMSA 2V4BA 1SMPA 1BIWA 3HDAP 1KUFA 1ROSA 3VTGA 2X7MA 3P24A 4FVLA 1XFXA 1IACA 4WF6A 4HX3A 2QPJA 1DMTA 1C3IA 4JQGA 1Y8JA 5D1TA 2MLSA 1HOVA 1BUDA 2D1OA 3LQBA 4ZR5A 5BPAA 2DW2A 1BKCE 1K7GA 3EDHA 3TT4A 3K7NA 1EB6A 1GKCA 5I43A 3KEJA 3LJGA 2RJPA 1OM7A 2XS4A 3KWVC 1KUGA 2W12A 3KHIA
chains in the Genus database with same CATH superfamily
1QJIA 3DWBA 3KRYA 2POJA 3LGPA 3HY7A 1EAKA 1KBCA 2X3AA 3U1RA 2DDFA 456CA 5I2ZA 3F15A 4ON1A 2YUFA 1K7IA 4PKTA 1C7KA 1JAOA 4DPEA 5H8XA 1KUKA 1Q3AA 4GQLA 2J83A 4PKUA 4H82A 1GO7P 1QJJA 1OM8A 1SRPA 2OXWA 3F17A 3TS4A 2FV9A 4GR0A 2J0TA 4H84A 5D1SA 1UEAA 1BKCA 3WV1A 4GWMA 3VI1A 1XUCA 1OZ9A 2MZIA 1GKDA 1MMRA 2ERQA 1I76A 3GBOA 1AYKA 3N2UA 3LIKA 3DPFA 3P1VA 4I35A 5B5PA 1SLNA 1BM6A 1GXDA 4XM8A 1JH1A 3EHXA 5CUHA 1BSWA 2OY4A 5BOYA 1IABA 4JP4A 4XBHA 2OVZA 4IN9A 1ND1A 2I47A 4G0DA 1TVIA 1D7XA 4PKQA 1JAPA 3HYGA 4AUOA 3DPEA 3F18A 3DTEA 1XUDA 1ASTA 2SRTA 1YCMA 3UVCA 1OS2A 2OW9A 1GE5A 3KECA 1SLMA 1XFVA 4JIJA 2OZRA 1HV5A 3SHIA 3LK8A 4DF9A 1R1HA 4XM6A 4QKZA 1XURA 1CK7A 1G05A 2W13A 3ELMA 3DTKA 2DW1A 1ZP5A 2MZHA 1PWVA 3EHYA 3WV3A 4A7BA 1H71P 1HFSA 2OXZA 2WOAA 1OS9A 3USNA 3N2VA 5CZMA 1BUVM 2WO8A 1FM1A 3DL1A 3L0TA 4PKVA 2N8RA 1XAXA 1Z3JA 2AYKA 2OI0A 3I7IA 4GWNA 2K9CA 1ZTQA 1ZXVA 2JSDA 1ATLA 2OW2A 1SU3A 1O0TA 2JT5A 4WKIA 4PKWA 4G9LA 1I1IP 2K2GA 3LIRA 5D3CA 2X3CA 4JPAA 1Y93A 1RMZA 1AF0A 1BZSA 5D1UA 4XM7A 5LABA 5I0LA 4AXQA 3LUNA 3EDGA 1WNIA 3KMCA 5CXAA 3EDIA 2Y6DA 3ZVSA 5L79A 1DTHA 2TCLA 2MZEA 2W0DA 1FLSA 1MMQA 1PWWA 2ERPA 2KRJA 1JIZA 3F16A 4H30A 3G42A 1BQOA 1B8YA 1MMBA 1RM8A 1K7QA 5I4OA 2FV5A 1IAEA 1AKLA 4I03A 5JMYA 1D8MA 2USNA 2JT6A 3DNGA 3LE9A 2OY2A 4AIGA 1XFYA 4L63A 3F1AA 3NX7A 4R3VA 4XCTA 2DW0A 3RTTA 1JJ9A 3EWJA 4GR3A 4Q1LA 3LKAA 4ILWD 3LUMA 3B2ZA 1PWQA 3HBUP 3B92A 3OHOA 3G5CA 1HFCA 3LEAA 2JNPA 3BA0A 1GE7A 1GE6A 4H76A 1G49A 4FXYP 1YP1A 1QIBA 2WO9A 1XFWA 2A8HA 1ZVXA 4GUYA 1CAQA 2YB9A 1CGFA 1D5JA 4GR8A 1UTZA 2O3EA 1C8TA 4IUWA 4H3XA 4HMAA 1R1IA 1R55A 3LJTA 2Y6CA 4J4MA 4FU4A 3Q2GA 4L19A 1CGEA 4DD8A 4EFSA 3I7GA 4A3WA 1IAGA 3CKIA 830CA 5I3MA 1B3DA 3TVCA 3HB2P 1Y0VA 3AIGA 1A86A 1S4BP 5I12A 4WKEA 1I73A 5L7FA 1EUBA 2EROA 3AYUA 2OVXA 1UMTA 5B5OA 1JAQA 2D1NA 2RJQA 1ZS0A 5D2BA 3KEKA 1KAPP 3O2XA 1HY7A 2DDYA 4PKRA 4H1QA 1BKCI 3F19A 3LJZA 3TSKA 3LILA 3WV2A 4L7AA 1FBLA 1OO9A 1R1JA 3LQ0A 1G4KA 1OM6A 3KMEA 2OW1A 5BOTA 4L6TA 1QICA 1SATA 3L0VA 1MMPA 1KUIA 2OXUA 1CQRA 3EDZA 2E2DA 1BQQM 1PWPA 1J7NA 4PKSA 4WK7A 1XFZA 4H49A 1XFUA 2JIHA 1USNA 3OHLA 4FXQA 2CLTA 1IADA 1MNCA 1QIAA 1R54A 1KUHA 3AYKA 1JANA 4CTHA 2PJTA 1QUAA 2Z2DA 2X3BA 1YQYA 3HY9A 1CIZA 3LMCA 3HBVP 1HTDA 1CGLA 1OMJA 2AIGP 3K7LA 3DSLA 1PWUA 1GO8P 4GF1A 1A85A 1UTTA 1ZXCA 1JIWP 1L6JA 2E3XA 3MA2A 1JK3A 2YIGA 2W15A 2MLRA 4JA1A 3O64A 5D7WA 4WZVA 2O36A 1YOUA 3Q2HA 3B8ZA 1G12A 4AYKA 3HDBA 3E8RA 1IAAA 4IJOA 1O0QA 2HU6A 3RTSA 2OW0A 2XS3A 2CKIA 1JKYA 3V96B 4H2EA 3ZUKA 3ZXHA 2W14A 2L0RA 4DV8A 1G9KA 1CXVA 1D8FA 966CA 1UMSA 2V4BA 1SMPA 1BIWA 3HDAP 1KUFA 1ROSA 3VTGA 2X7MA 3P24A 4FVLA 1XFXA 1IACA 4WF6A 4HX3A 1XM5A 1DMTA 2QPJA 1C3IA 4JQGA 1Y8JA 5D1TA 2MLSA 1HOVA 1BUDA 2D1OA 3LQBA 4ZR5A 5BPAA 2DW2A 1BKCE 1K7GA 3EDHA 3TT4A 3K7NA 1EB6A 1GKCA 5I43A 3KEJA 3LJGA 2RJPA 3DTIA 1OM7A 2XS4A 3KWVC 1KUGA 2W12A 3KHIA
chains in the Genus database with same CATH topology
1QJIA 3DWBA 3KRYA 2POJA 3LGPA 3HY7A 1EAKA 1KBCA 2X3AA 3U1RA 2DDFA 456CA 5I2ZA 3F15A 4ON1A 2YUFA 1K7IA 4PKTA 1C7KA 1JAOA 4DPEA 5H8XA 1KUKA 1Q3AA 4GQLA 2J83A 4PKUA 4H82A 1GO7P 1QJJA 1OM8A 1SRPA 2OXWA 3F17A 3TS4A 2FV9A 4GR0A 2J0TA 4H84A 5D1SA 1UEAA 1BKCA 3WV1A 4GWMA 3VI1A 1XUCA 2MZIA 1GKDA 1MMRA 2ERQA 1I76A 3GBOA 1AYKA 3N2UA 3LIKA 3DPFA 3P1VA 4I35A 5B5PA 1SLNA 1BM6A 1GXDA 4XM8A 1JH1A 3EHXA 5CUHA 1BSWA 2OY4A 5BOYA 1IABA 4JP4A 4XBHA 2OVZA 4IN9A 1ND1A 2I47A 4G0DA 4PKQA 1D7XA 1JAPA 3HYGA 4AUOA 3DPEA 3F18A 3DTEA 1XUDA 1ASTA 2SRTA 1YCMA 3UVCA 1OS2A 2OW9A 1GE5A 3KECA 1SLMA 1XFVA 4JIJA 2OZRA 1HV5A 3SHIA 3LK8A 4DF9A 1R1HA 4XM6A 4QKZA 1XURA 1CK7A 1G05A 2W13A 3ELMA 3DTKA 2DW1A 1ZP5A 2MZHA 1PWVA 3EHYA 3WV3A 4A7BA 1H71P 1HFSA 2OXZA 2WOAA 1OS9A 3USNA 3N2VA 5CZMA 1BUVM 2WO8A 1FM1A 3DL1A 3L0TA 4PKVA 2N8RA 1Z3JA 2AYKA 2OI0A 3I7IA 4GWNA 2K9CA 1ZTQA 1ZXVA 2JSDA 1ATLA 2OW2A 1SU3A 1O0TA 2JT5A 4WKIA 4PKWA 4G9LA 1I1IP 2K2GA 3LIRA 5D3CA 2X3CA 4JPAA 1Y93A 1RMZA 1AF0A 1BZSA 5D1UA 4XM7A 5LABA 5I0LA 4AXQA 3LUNA 3EDGA 1WNIA 3KMCA 5CXAA 3EDIA 2Y6DA 3ZVSA 5L79A 1DTHA 2TCLA 2MZEA 2W0DA 1FLSA 1MMQA 1PWWA 2ERPA 2KRJA 1JIZA 3F16A 4H30A 3G42A 1BQOA 1B8YA 1MMBA 1RM8A 1K7QA 5I4OA 2FV5A 1IAEA 1AKLA 4I03A 5JMYA 1D8MA 2USNA 2JT6A 3DNGA 3LE9A 2OY2A 4AIGA 1XFYA 4L63A 3F1AA 3NX7A 4R3VA 4XCTA 2DW0A 3RTTA 1JJ9A 3EWJA 4GR3A 4Q1LA 3LKAA 4ILWD 3LUMA 3B2ZA 1PWQA 3HBUP 3B92A 3OHOA 3G5CA 1HFCA 3LEAA 2JNPA 3BA0A 1GE7A 1GE6A 4H76A 1G49A 4FXYP 1YP1A 1QIBA 2WO9A 1XFWA 2A8HA 1ZVXA 4GUYA 1CAQA 2YB9A 1CGFA 1D5JA 4GR8A 1UTZA 2O3EA 1C8TA 4IUWA 4H3XA 4HMAA 1R1IA 1R55A 3LJTA 2Y6CA 4J4MA 4FU4A 3Q2GA 4L19A 1CGEA 4DD8A 4EFSA 3I7GA 4A3WA 1IAGA 3CKIA 830CA 5I3MA 1B3DA 3TVCA 3HB2P 1Y0VA 3AIGA 1A86A 1S4BP 5I12A 4WKEA 1I73A 5L7FA 1EUBA 2EROA 3AYUA 2OVXA 1UMTA 5B5OA 1JAQA 2D1NA 2RJQA 1ZS0A 5D2BA 3KEKA 1KAPP 3O2XA 1HY7A 2DDYA 4PKRA 4H1QA 1BKCI 3F19A 3LJZA 3TSKA 3LILA 3WV2A 4L7AA 1FBLA 1OO9A 1R1JA 3LQ0A 1G4KA 1OM6A 3KMEA 2OW1A 5BOTA 4L6TA 1QICA 1SATA 3L0VA 1MMPA 1KUIA 2OXUA 1CQRA 3EDZA 2E2DA 1BQQM 1PWPA 1J7NA 4PKSA 4WK7A 1XFZA 4H49A 1XFUA 2JIHA 1USNA 3OHLA 4FXQA 2CLTA 1IADA 1MNCA 1QIAA 1R54A 1KUHA 3AYKA 1JANA 4CTHA 2PJTA 1QUAA 2Z2DA 2X3BA 1YQYA 3HY9A 1CIZA 3LMCA 3HBVP 1HTDA 1CGLA 1OMJA 2AIGP 3K7LA 3DSLA 1PWUA 1GO8P 4GF1A 1A85A 1UTTA 1ZXCA 1JIWP 1L6JA 2E3XA 3MA2A 1JK3A 2YIGA 2W15A 2MLRA 4JA1A 3O64A 5D7WA 4WZVA 2O36A 1YOUA 3Q2HA 3B8ZA 1G12A 4AYKA 3HDBA 3E8RA 1IAAA 4IJOA 1O0QA 2HU6A 3RTSA 2OW0A 2XS3A 2CKIA 1JKYA 3V96B 4H2EA 3ZUKA 3ZXHA 2W14A 2L0RA 4DV8A 1G9KA 1CXVA 1D8FA 966CA 1UMSA 2V4BA 1SMPA 1BIWA 3HDAP 1KUFA 1ROSA 3VTGA 2X7MA 3P24A 4FVLA 1XFXA 1IACA 4WF6A 4HX3A 2QPJA 1DMTA 1C3IA 4JQGA 1Y8JA 5D1TA 2MLSA 1HOVA 1BUDA 2D1OA 3LQBA 4ZR5A 5BPAA 2DW2A 1BKCE 1K7GA 3EDHA 3TT4A 3K7NA 1EB6A 1GKCA 5I43A 3KEJA 3LJGA 2RJPA 3DTIA 1OM7A 2XS4A 3KWVC 1KUGA 2W12A 3KHIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QJI A;  3DWB A;  3KRY A;  2POJ A;  3LGP A;  3HY7 A;  1EAK A;  1KBC A;  2X3A A;  3U1R A;  2DDF A;  456C A;  5I2Z A;  3F15 A;  4ON1 A;  1K7I A;  4PKT A;  1C7K A;  1JAO A;  4DPE A;  5H8X A;  1KUK A;  1Q3A A;  4GQL A;  2J83 A;  4PKU A;  4H82 A;  1GO7 P;  1QJJ A;  1OM8 A;  1SRP A;  2OXW A;  3F17 A;  3TS4 A;  2FV9 A;  4GR0 A;  2J0T A;  4H84 A;  5D1S A;  1UEA A;  1BKC A;  3WV1 A;  4GWM A;  3VI1 A;  1XUC A;  2MZI A;  1GKD A;  1MMR A;  2ERQ A;  1I76 A;  3GBO A;  1AYK A;  3N2U A;  3LIK A;  3DPF A;  3P1V A;  4I35 A;  5B5P A;  1SLN A;  1BM6 A;  1GXD A;  4XM8 A;  1JH1 A;  3EHX A;  5CUH A;  1BSW A;  2OY4 A;  5BOY A;  1IAB A;  4JP4 A;  4XBH A;  2OVZ A;  4IN9 A;  1ND1 A;  2I47 A;  4G0D A;  4PKQ A;  1D7X A;  1JAP A;  3HYG A;  4AUO A;  3DPE A;  3F18 A;  1XUD A;  1AST A;  2SRT A;  1YCM A;  3UVC A;  1OS2 A;  2OW9 A;  1GE5 A;  3KEC A;  1SLM A;  1XFV A;  4JIJ A;  2OZR A;  1HV5 A;  3SHI A;  3LK8 A;  4DF9 A;  1R1H A;  4XM6 A;  4QKZ A;  1XUR A;  1CK7 A;  1G05 A;  2W13 A;  3ELM A;  2DW1 A;  1ZP5 A;  2MZH A;  1PWV A;  3EHY A;  3WV3 A;  4A7B A;  1H71 P;  1HFS A;  2OXZ A;  2WOA A;  1OS9 A;  3USN A;  3N2V A;  5CZM A;  1BUV M;  2WO8 A;  1FM1 A;  3DL1 A;  3L0T A;  4PKV A;  2N8R A;  1Z3J A;  2AYK A;  2OI0 A;  3I7I A;  4GWN A;  2K9C A;  1ZTQ A;  1ZXV A;  2JSD A;  1ATL A;  2OW2 A;  1SU3 A;  1O0T A;  2JT5 A;  4WKI A;  4PKW A;  4G9L A;  1I1I P;  2K2G A;  3LIR A;  5D3C A;  2X3C A;  4JPA A;  1Y93 A;  1RMZ A;  1AF0 A;  1BZS A;  5D1U A;  4XM7 A;  5LAB A;  5I0L A;  4AXQ A;  3LUN A;  3EDG A;  1WNI A;  3KMC A;  5CXA A;  3EDI A;  2Y6D A;  3ZVS A;  5L79 A;  1DTH A;  2TCL A;  2MZE A;  2W0D A;  1FLS A;  1MMQ A;  1PWW A;  2ERP A;  2KRJ A;  1JIZ A;  3F16 A;  4H30 A;  3G42 A;  1BQO A;  1B8Y A;  1MMB A;  1RM8 A;  1K7Q A;  5I4O A;  2FV5 A;  1IAE A;  1AKL A;  4I03 A;  5JMY A;  1D8M A;  2USN A;  2JT6 A;  3DNG A;  3LE9 A;  2OY2 A;  4AIG A;  1XFY A;  4L63 A;  3F1A A;  3NX7 A;  4R3V A;  4XCT A;  2DW0 A;  3RTT A;  1JJ9 A;  3EWJ A;  4GR3 A;  4Q1L A;  3LKA A;  4ILW D;  3LUM A;  3B2Z A;  1PWQ A;  3HBU P;  3B92 A;  3OHO A;  3G5C A;  1HFC A;  3LEA A;  2JNP A;  3BA0 A;  1GE7 A;  1GE6 A;  4H76 A;  1G49 A;  4FXY P;  1YP1 A;  1QIB A;  2WO9 A;  1XFW A;  2A8H A;  1ZVX A;  4GUY A;  1CAQ A;  2YB9 A;  1CGF A;  1D5J A;  4GR8 A;  1UTZ A;  2O3E A;  1C8T A;  4IUW A;  4H3X A;  4HMA A;  1R1I A;  1R55 A;  3LJT A;  2Y6C A;  4J4M A;  4FU4 A;  3Q2G A;  4L19 A;  1CGE A;  4DD8 A;  4EFS A;  3I7G A;  4A3W A;  1IAG A;  3CKI A;  830C A;  5I3M A;  1B3D A;  3TVC A;  3HB2 P;  1Y0V A;  3AIG A;  1A86 A;  1S4B P;  5I12 A;  4WKE A;  1I73 A;  5L7F A;  1EUB A;  2ERO A;  3AYU A;  2OVX A;  1UMT A;  5B5O A;  1JAQ A;  2D1N A;  2RJQ A;  1ZS0 A;  5D2B A;  3KEK A;  1KAP P;  3O2X A;  1HY7 A;  2DDY A;  4PKR A;  4H1Q A;  1BKC I;  3F19 A;  3LJZ A;  3TSK A;  3LIL A;  3WV2 A;  1FBL A;  1OO9 A;  1R1J A;  3LQ0 A;  1G4K A;  1OM6 A;  3KME A;  2OW1 A;  5BOT A;  4L6T A;  1QIC A;  1SAT A;  3L0V A;  1MMP A;  1KUI A;  2OXU A;  1CQR A;  3EDZ A;  2E2D A;  1BQQ M;  1PWP A;  1J7N A;  4PKS A;  4WK7 A;  1XFZ A;  4H49 A;  1XFU A;  2JIH A;  1USN A;  3OHL A;  4FXQ A;  2CLT A;  1IAD A;  1MNC A;  1QIA A;  1R54 A;  1KUH A;  3AYK A;  1JAN A;  4CTH A;  2PJT A;  1QUA A;  2Z2D A;  2X3B A;  1YQY A;  3HY9 A;  1CIZ A;  3LMC A;  3HBV P;  1HTD A;  1CGL A;  1OMJ A;  2AIG P;  3K7L A;  3DSL A;  1PWU A;  1GO8 P;  4GF1 A;  1A85 A;  1UTT A;  1ZXC A;  1JIW P;  1L6J A;  2E3X A;  3MA2 A;  1JK3 A;  2YIG A;  2W15 A;  2MLR A;  4JA1 A;  3O64 A;  5D7W A;  4WZV A;  2O36 A;  1YOU A;  3Q2H A;  3B8Z A;  1G12 A;  4AYK A;  3HDB A;  3E8R A;  1IAA A;  4IJO A;  1O0Q A;  2HU6 A;  3RTS A;  2OW0 A;  2XS3 A;  2CKI A;  1JKY A;  3V96 B;  4H2E A;  3ZUK A;  3ZXH A;  2W14 A;  2L0R A;  4DV8 A;  1G9K A;  1CXV A;  1D8F A;  966C A;  1UMS A;  2V4B A;  1SMP A;  1BIW A;  3HDA P;  1KUF A;  1ROS A;  3VTG A;  2X7M A;  3P24 A;  4FVL A;  1XFX A;  1IAC A;  4WF6 A;  4HX3 A;  2QPJ A;  1DMT A;  1C3I A;  4JQG A;  1Y8J A;  5D1T A;  2MLS A;  1HOV A;  1BUD A;  2D1O A;  3LQB A;  4ZR5 A;  5BPA A;  2DW2 A;  1BKC E;  1K7G A;  3EDH A;  3TT4 A;  3K7N A;  1EB6 A;  1GKC A;  5I43 A;  3KEJ A;  3LJG A;  2RJP A;  1OM7 A;  2XS4 A;  3KWV C;  1KUG A;  2W12 A;  3KHI A; 
#chains in the Genus database with same CATH topology
 1QJI A;  3DWB A;  3KRY A;  2POJ A;  3LGP A;  3HY7 A;  1EAK A;  1KBC A;  2X3A A;  3U1R A;  2DDF A;  456C A;  5I2Z A;  3F15 A;  4ON1 A;  2YUF A;  1K7I A;  4PKT A;  1C7K A;  1JAO A;  4DPE A;  5H8X A;  1KUK A;  1Q3A A;  4GQL A;  2J83 A;  4PKU A;  4H82 A;  1GO7 P;  1QJJ A;  1OM8 A;  1SRP A;  2OXW A;  3F17 A;  3TS4 A;  2FV9 A;  4GR0 A;  2J0T A;  4H84 A;  5D1S A;  1UEA A;  1BKC A;  3WV1 A;  4GWM A;  3VI1 A;  1XUC A;  1OZ9 A;  2MZI A;  1GKD A;  1MMR A;  2ERQ A;  1I76 A;  3GBO A;  1AYK A;  3N2U A;  3LIK A;  3DPF A;  3P1V A;  4I35 A;  5B5P A;  1SLN A;  1BM6 A;  1GXD A;  4XM8 A;  1JH1 A;  3EHX A;  5CUH A;  1BSW A;  2OY4 A;  5BOY A;  1IAB A;  4JP4 A;  4XBH A;  2OVZ A;  4IN9 A;  1ND1 A;  2I47 A;  4G0D A;  1TVI A;  1D7X A;  4PKQ A;  1JAP A;  3HYG A;  4AUO A;  3DPE A;  3F18 A;  3DTE A;  1XUD A;  1AST A;  2SRT A;  1YCM A;  3UVC A;  1OS2 A;  2OW9 A;  1GE5 A;  3KEC A;  1SLM A;  1XFV A;  4JIJ A;  2OZR A;  1HV5 A;  3SHI A;  3LK8 A;  4DF9 A;  1R1H A;  4XM6 A;  4QKZ A;  1XUR A;  1CK7 A;  1G05 A;  2W13 A;  3ELM A;  3DTK A;  2DW1 A;  1ZP5 A;  2MZH A;  1PWV A;  3EHY A;  3WV3 A;  4A7B A;  1H71 P;  1HFS A;  2OXZ A;  2WOA A;  1OS9 A;  3USN A;  3N2V A;  5CZM A;  1BUV M;  2WO8 A;  1FM1 A;  3DL1 A;  3L0T A;  4PKV A;  2N8R A;  1XAX A;  1Z3J A;  2AYK A;  2OI0 A;  3I7I A;  4GWN A;  2K9C A;  1ZTQ A;  1ZXV A;  2JSD A;  1ATL A;  2OW2 A;  1SU3 A;  1O0T A;  2JT5 A;  4WKI A;  4PKW A;  4G9L A;  1I1I P;  2K2G A;  3LIR A;  5D3C A;  2X3C A;  4JPA A;  1Y93 A;  1RMZ A;  1AF0 A;  1BZS A;  5D1U A;  4XM7 A;  5LAB A;  5I0L A;  4AXQ A;  3LUN A;  3EDG A;  1WNI A;  3KMC A;  5CXA A;  3EDI A;  2Y6D A;  3ZVS A;  5L79 A;  1DTH A;  2TCL A;  2MZE A;  2W0D A;  1FLS A;  1MMQ A;  1PWW A;  2ERP A;  2KRJ A;  1JIZ A;  3F16 A;  4H30 A;  3G42 A;  1BQO A;  1B8Y A;  1MMB A;  1RM8 A;  1K7Q A;  5I4O A;  2FV5 A;  1IAE A;  1AKL A;  4I03 A;  5JMY A;  1D8M A;  2USN A;  2JT6 A;  3DNG A;  3LE9 A;  2OY2 A;  4AIG A;  1XFY A;  4L63 A;  3F1A A;  3NX7 A;  4R3V A;  4XCT A;  2DW0 A;  3RTT A;  1JJ9 A;  3EWJ A;  4GR3 A;  4Q1L A;  3LKA A;  4ILW D;  3LUM A;  3B2Z A;  1PWQ A;  3HBU P;  3B92 A;  3OHO A;  3G5C A;  1HFC A;  3LEA A;  2JNP A;  3BA0 A;  1GE7 A;  1GE6 A;  4H76 A;  1G49 A;  4FXY P;  1YP1 A;  1QIB A;  2WO9 A;  1XFW A;  2A8H A;  1ZVX A;  4GUY A;  1CAQ A;  2YB9 A;  1CGF A;  1D5J A;  4GR8 A;  1UTZ A;  2O3E A;  1C8T A;  4IUW A;  4H3X A;  4HMA A;  1R1I A;  1R55 A;  3LJT A;  2Y6C A;  4J4M A;  4FU4 A;  3Q2G A;  4L19 A;  1CGE A;  4DD8 A;  4EFS A;  3I7G A;  4A3W A;  1IAG A;  3CKI A;  830C A;  5I3M A;  1B3D A;  3TVC A;  3HB2 P;  1Y0V A;  3AIG A;  1A86 A;  1S4B P;  5I12 A;  4WKE A;  1I73 A;  5L7F A;  1EUB A;  2ERO A;  3AYU A;  2OVX A;  1UMT A;  5B5O A;  1JAQ A;  2D1N A;  2RJQ A;  1ZS0 A;  5D2B A;  3KEK A;  1KAP P;  3O2X A;  1HY7 A;  2DDY A;  4PKR A;  4H1Q A;  1BKC I;  3F19 A;  3LJZ A;  3TSK A;  3LIL A;  3WV2 A;  4L7A A;  1FBL A;  1OO9 A;  1R1J A;  3LQ0 A;  1G4K A;  1OM6 A;  3KME A;  2OW1 A;  5BOT A;  4L6T A;  1QIC A;  1SAT A;  3L0V A;  1MMP A;  1KUI A;  2OXU A;  1CQR A;  3EDZ A;  2E2D A;  1BQQ M;  1PWP A;  1J7N A;  4PKS A;  4WK7 A;  1XFZ A;  4H49 A;  1XFU A;  2JIH A;  1USN A;  3OHL A;  4FXQ A;  2CLT A;  1IAD A;  1MNC A;  1QIA A;  1R54 A;  1KUH A;  3AYK A;  1JAN A;  4CTH A;  2PJT A;  1QUA A;  2Z2D A;  2X3B A;  1YQY A;  3HY9 A;  1CIZ A;  3LMC A;  3HBV P;  1HTD A;  1CGL A;  1OMJ A;  2AIG P;  3K7L A;  3DSL A;  1PWU A;  1GO8 P;  4GF1 A;  1A85 A;  1UTT A;  1ZXC A;  1JIW P;  1L6J A;  2E3X A;  3MA2 A;  1JK3 A;  2YIG A;  2W15 A;  2MLR A;  4JA1 A;  3O64 A;  5D7W A;  4WZV A;  2O36 A;  1YOU A;  3Q2H A;  3B8Z A;  1G12 A;  4AYK A;  3HDB A;  3E8R A;  1IAA A;  4IJO A;  1O0Q A;  2HU6 A;  3RTS A;  2OW0 A;  2XS3 A;  2CKI A;  1JKY A;  3V96 B;  4H2E A;  3ZUK A;  3ZXH A;  2W14 A;  2L0R A;  4DV8 A;  1G9K A;  1CXV A;  1D8F A;  966C A;  1UMS A;  2V4B A;  1SMP A;  1BIW A;  3HDA P;  1KUF A;  1ROS A;  3VTG A;  2X7M A;  3P24 A;  4FVL A;  1XFX A;  1IAC A;  4WF6 A;  4HX3 A;  1XM5 A;  1DMT A;  2QPJ A;  1C3I A;  4JQG A;  1Y8J A;  5D1T A;  2MLS A;  1HOV A;  1BUD A;  2D1O A;  3LQB A;  4ZR5 A;  5BPA A;  2DW2 A;  1BKC E;  1K7G A;  3EDH A;  3TT4 A;  3K7N A;  1EB6 A;  1GKC A;  5I43 A;  3KEJ A;  3LJG A;  2RJP A;  3DTI A;  1OM7 A;  2XS4 A;  3KWV C;  1KUG A;  2W12 A;  3KHI A; 
#chains in the Genus database with same CATH homology
 1QJI A;  3DWB A;  3KRY A;  2POJ A;  3LGP A;  3HY7 A;  1EAK A;  1KBC A;  2X3A A;  3U1R A;  2DDF A;  456C A;  5I2Z A;  3F15 A;  4ON1 A;  2YUF A;  1K7I A;  4PKT A;  1C7K A;  1JAO A;  4DPE A;  5H8X A;  1KUK A;  1Q3A A;  4GQL A;  2J83 A;  4PKU A;  4H82 A;  1GO7 P;  1QJJ A;  1OM8 A;  1SRP A;  2OXW A;  3F17 A;  3TS4 A;  2FV9 A;  4GR0 A;  2J0T A;  4H84 A;  5D1S A;  1UEA A;  1BKC A;  3WV1 A;  4GWM A;  3VI1 A;  1XUC A;  2MZI A;  1GKD A;  1MMR A;  2ERQ A;  1I76 A;  3GBO A;  1AYK A;  3N2U A;  3LIK A;  3DPF A;  3P1V A;  4I35 A;  5B5P A;  1SLN A;  1BM6 A;  1GXD A;  4XM8 A;  1JH1 A;  3EHX A;  5CUH A;  1BSW A;  2OY4 A;  5BOY A;  1IAB A;  4JP4 A;  4XBH A;  2OVZ A;  4IN9 A;  1ND1 A;  2I47 A;  4G0D A;  4PKQ A;  1D7X A;  1JAP A;  3HYG A;  4AUO A;  3DPE A;  3F18 A;  3DTE A;  1XUD A;  1AST A;  2SRT A;  1YCM A;  3UVC A;  1OS2 A;  2OW9 A;  1GE5 A;  3KEC A;  1SLM A;  1XFV A;  4JIJ A;  2OZR A;  1HV5 A;  3SHI A;  3LK8 A;  4DF9 A;  1R1H A;  4XM6 A;  4QKZ A;  1XUR A;  1CK7 A;  1G05 A;  2W13 A;  3ELM A;  3DTK A;  2DW1 A;  1ZP5 A;  2MZH A;  1PWV A;  3EHY A;  3WV3 A;  4A7B A;  1H71 P;  1HFS A;  2OXZ A;  2WOA A;  1OS9 A;  3USN A;  3N2V A;  5CZM A;  1BUV M;  2WO8 A;  1FM1 A;  3DL1 A;  3L0T A;  4PKV A;  2N8R A;  1Z3J A;  2AYK A;  2OI0 A;  3I7I A;  4GWN A;  2K9C A;  1ZTQ A;  1ZXV A;  2JSD A;  1ATL A;  2OW2 A;  1SU3 A;  1O0T A;  2JT5 A;  4WKI A;  4PKW A;  4G9L A;  1I1I P;  2K2G A;  3LIR A;  5D3C A;  2X3C A;  4JPA A;  1Y93 A;  1RMZ A;  1AF0 A;  1BZS A;  5D1U A;  4XM7 A;  5LAB A;  5I0L A;  4AXQ A;  3LUN A;  3EDG A;  1WNI A;  3KMC A;  5CXA A;  3EDI A;  2Y6D A;  3ZVS A;  5L79 A;  1DTH A;  2TCL A;  2MZE A;  2W0D A;  1FLS A;  1MMQ A;  1PWW A;  2ERP A;  2KRJ A;  1JIZ A;  3F16 A;  4H30 A;  3G42 A;  1BQO A;  1B8Y A;  1MMB A;  1RM8 A;  1K7Q A;  5I4O A;  2FV5 A;  1IAE A;  1AKL A;  4I03 A;  5JMY A;  1D8M A;  2USN A;  2JT6 A;  3DNG A;  3LE9 A;  2OY2 A;  4AIG A;  1XFY A;  4L63 A;  3F1A A;  3NX7 A;  4R3V A;  4XCT A;  2DW0 A;  3RTT A;  1JJ9 A;  3EWJ A;  4GR3 A;  4Q1L A;  3LKA A;  4ILW D;  3LUM A;  3B2Z A;  1PWQ A;  3HBU P;  3B92 A;  3OHO A;  3G5C A;  1HFC A;  3LEA A;  2JNP A;  3BA0 A;  1GE7 A;  1GE6 A;  4H76 A;  1G49 A;  4FXY P;  1YP1 A;  1QIB A;  2WO9 A;  1XFW A;  2A8H A;  1ZVX A;  4GUY A;  1CAQ A;  2YB9 A;  1CGF A;  1D5J A;  4GR8 A;  1UTZ A;  2O3E A;  1C8T A;  4IUW A;  4H3X A;  4HMA A;  1R1I A;  1R55 A;  3LJT A;  2Y6C A;  4J4M A;  4FU4 A;  3Q2G A;  4L19 A;  1CGE A;  4DD8 A;  4EFS A;  3I7G A;  4A3W A;  1IAG A;  3CKI A;  830C A;  5I3M A;  1B3D A;  3TVC A;  3HB2 P;  1Y0V A;  3AIG A;  1A86 A;  1S4B P;  5I12 A;  4WKE A;  1I73 A;  5L7F A;  1EUB A;  2ERO A;  3AYU A;  2OVX A;  1UMT A;  5B5O A;  1JAQ A;  2D1N A;  2RJQ A;  1ZS0 A;  5D2B A;  3KEK A;  1KAP P;  3O2X A;  1HY7 A;  2DDY A;  4PKR A;  4H1Q A;  1BKC I;  3F19 A;  3LJZ A;  3TSK A;  3LIL A;  3WV2 A;  4L7A A;  1FBL A;  1OO9 A;  1R1J A;  3LQ0 A;  1G4K A;  1OM6 A;  3KME A;  2OW1 A;  5BOT A;  4L6T A;  1QIC A;  1SAT A;  3L0V A;  1MMP A;  1KUI A;  2OXU A;  1CQR A;  3EDZ A;  2E2D A;  1BQQ M;  1PWP A;  1J7N A;  4PKS A;  4WK7 A;  1XFZ A;  4H49 A;  1XFU A;  2JIH A;  1USN A;  3OHL A;  4FXQ A;  2CLT A;  1IAD A;  1MNC A;  1QIA A;  1R54 A;  1KUH A;  3AYK A;  1JAN A;  4CTH A;  2PJT A;  1QUA A;  2Z2D A;  2X3B A;  1YQY A;  3HY9 A;  1CIZ A;  3LMC A;  3HBV P;  1HTD A;  1CGL A;  1OMJ A;  2AIG P;  3K7L A;  3DSL A;  1PWU A;  1GO8 P;  4GF1 A;  1A85 A;  1UTT A;  1ZXC A;  1JIW P;  1L6J A;  2E3X A;  3MA2 A;  1JK3 A;  2YIG A;  2W15 A;  2MLR A;  4JA1 A;  3O64 A;  5D7W A;  4WZV A;  2O36 A;  1YOU A;  3Q2H A;  3B8Z A;  1G12 A;  4AYK A;  3HDB A;  3E8R A;  1IAA A;  4IJO A;  1O0Q A;  2HU6 A;  3RTS A;  2OW0 A;  2XS3 A;  2CKI A;  1JKY A;  3V96 B;  4H2E A;  3ZUK A;  3ZXH A;  2W14 A;  2L0R A;  4DV8 A;  1G9K A;  1CXV A;  1D8F A;  966C A;  1UMS A;  2V4B A;  1SMP A;  1BIW A;  3HDA P;  1KUF A;  1ROS A;  3VTG A;  2X7M A;  3P24 A;  4FVL A;  1XFX A;  1IAC A;  4WF6 A;  4HX3 A;  2QPJ A;  1DMT A;  1C3I A;  4JQG A;  1Y8J A;  5D1T A;  2MLS A;  1HOV A;  1BUD A;  2D1O A;  3LQB A;  4ZR5 A;  5BPA A;  2DW2 A;  1BKC E;  1K7G A;  3EDH A;  3TT4 A;  3K7N A;  1EB6 A;  1GKC A;  5I43 A;  3KEJ A;  3LJG A;  2RJP A;  3DTI A;  1OM7 A;  2XS4 A;  3KWV C;  1KUG A;  2W12 A;  3KHI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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