4ILWD

Complex of matrix metalloproteinase-10 catalytic domain (mmp-10cd) with tissue inhibitor of metalloproteinases-2 (timp-2)
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
159
structure length
159
Chain Sequence
MPKWRKTHLTYRIVNYTPDLPRDAVDSAIEKALKVWEEVTPLTFSRLYEGEADIMISFAVKEHGDFYSFDGPGHSLAHAYPPGPGLYGDIHFDDDEKWTEDASGTNLFLVAAHELGHSLGLFHSANTEALMYPLYNSFTELAQFRLSQDDVNGIQSLYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Matrix Metalloproteinase-10/TIMP-2 Structure and Analyses Define Conserved Core Interactions and Diverse Exosite Interactions in MMP/TIMP Complexes.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Metalloproteinase inhibitor 2
total genus 45
structure length 159
sequence length 159
chains with identical sequence F
ec nomenclature ec 3.4.24.22: Stromelysin 2.
pdb deposition date 2013-01-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 4ilwD00
3F19A 3LQBA 4PKSA 1SLNA 3G5CA 1MNCA 3KECA 2K9CA 1K7IA 1UEAA 1YQYA 1C8TA 1GE7A 1PWQA 4PKWA 1FM1A 4FVLA 2MLRA 3TVCA 1ZXVA 3LGPA 5BOYA 1QIBA 3DPFA 2OXWA 4XM8A 3LQ0A 2O3EA 2OY4A 2X3AA 1SATA 1HY7A 1YP1A 1KUGA 1C3IA 5D1UA 2CLTA 2JIHA 3LJGA 1JIZA 3I7GA 2FV5A 1HTDA 2D1NA 1H71P 3VTGA 1BUDA 3TSKA 1EB6A 1JH1A 4I35A 5B5PA 4H30A 2MZIA 1OS9A 4XCTA 1OS2A 1JKYA 1G12A 1R1JA 3LE9A 1I76A 4GWMA 4H2EA 1PWWA 3V96B 2TCLA 2WOAA 1HV5A 4H49A 3LKAA 3LUMA 1BKCA 5H8XA 2XS3A 4H1QA 5I43A 2A8HA 1O0QA 3EDHA 2JT5A 2CKIA 1R1HA 1CXVA 4JPAA 1ASTA 3UVCA 1UMSA 3N2VA 1XFYA 3F15A 1SMPA 3L0VA 4G9LA 5B5OA 4GF1A 1K7QA 4DF9A 1ND1A 4H84A 2YB9A 5D3CA 1Y0VA 3WV3A 5I12A 4HX3A 1OO9A 3B2ZA 1ROSA 1BQOA 1D8MA 3AYUA 2SRTA 3F18A 3DNGA 3Q2HA 4L6TA 1XUDA 2DW1A 1HFCA 2OW2A 1D5JA 1ZXCA 4AXQA 1UTTA 2W15A 1WNIA 4WF6A 4FXQA 1YOUA 1PWUA 3WV1A 2DDYA 1IAGA 1DMTA 4I03A 2OZRA 4L63A 2W0DA 3DSLA 3EDGA 1I1IP 3EHYA 1R1IA 2HU6A 1EAKA 2FV9A 2PJTA 4J4MA 830CA 2I47A 2V4BA 456CA 2MZHA 3TT4A 3LMCA 3L0TA 1S4BP 2D1OA 1G4KA 2MZEA 1CGEA 3O64A 3Q2GA 1R55A 4IUWA 1IAAA 2RJQA 3LIKA 3GBOA 3KRYA 4XM7A 3DL1A 2X7MA 3HY7A 4ON1A 4G0DA 3RTSA 3K7LA 3HBVP 2X3BA 2OW0A 3CKIA 3OHOA 5D1TA 4WK7A 1B3DA 1IACA 1JK3A 4GUYA 1JANA 1J7NA 4WZVA 3P1VA 1JJ9A 2L0RA 1R54A 2XS4A 1KUKA 2W13A 3EDIA 2K2GA 2QPJA 5I4OA 1IABA 3I7IA 3ZUKA 1GXDA 3HDBA 4PKTA 1IAEA 1OM6A 4PKRA 5CXAA 1BZSA 1UTZA 1D7XA 4EFSA 3KWVC 2W14A 1GKCA 3E8RA 1BIWA 1BM6A 3KEKA 1JIWP 2E2DA 1KAPP 3KHIA 3ZXHA 1D8FA 2USNA 5CZMA 3N2UA 3EWJA 3BA0A 2MLSA 1HOVA 4H82A 2AIGP 3NX7A 2OY2A 2J83A 2WO8A 1CGFA 1MMQA 2OXZA 1A86A 1I73A 4GQLA 1MMBA 3LIRA 1AF0A 1EUBA 3HDAP 5L7FA 3SHIA 1KUIA 4DPEA 3TS4A 3EHXA 1DTHA 1G05A 1B8YA 2OW9A 1KBCA 4Q1LA 4A3WA 5I3MA 1XUCA 3LK8A 1KUHA 1BQQM 5CUHA 4GR8A 3F16A 1HFSA 1IADA 1XFWA 3U1RA 3F1AA 1GE5A 1FBLA 3ELMA 3USNA 1Y93A 2DDFA 1CIZA 1OM8A 3K7NA 966CA 2O36A 3LJTA 1QICA 4XBHA 2OW1A 4GR0A 3AYKA 1ATLA 1SRPA 1XFUA 1QIAA 4WKEA 2ERPA 1RMZA 3AIGA 4FU4A 4JP4A 5D7WA 4JQGA 4IN9A 1CQRA 2E3XA 3F17A 1OM7A 2RJPA 2KRJA 3LEAA 1FLSA 1AKLA 4JA1A 3KMCA 4GWNA 4FXYP 1ZVXA 2JNPA 4ILWD 2Y6CA 2W12A 3DPEA 1JAPA 5I2ZA 3ZVSA 3KEJA 2OI0A 1GO7P 3P24A 4L19A 1CAQA 5BOTA 1JAQA 1K7GA 1GO8P 4XM6A 3OHLA 2DW0A 2OVXA 2Y6DA 1QUAA 1XFXA 3O2XA 2OVZA 4AYKA 1CK7A 1ZP5A 3B92A 2ERQA 1L6JA 1OMJA 4HMAA 5D1SA 2JT6A 3DWBA 4GR3A 1XFZA 4PKUA 1BUVM 1G49A 1MMPA 1USNA 1BKCI 3EDZA 2Z2DA 4A7BA 4WKIA 4CTHA 5L79A 1BSWA 1BKCE 1G9KA 1GKDA 1QJJA 1CGLA 2DW2A 1KUFA 3LUNA 1ZTQA 3HBUP 3HYGA 1UMTA 2OXUA 5JMYA 5D2BA 1C7KA 1MMRA 1YCMA 2POJA 4PKVA 4JIJA 3MA2A 4ZR5A 4IJOA 3HB2P 4PKQA 4AIGA 3WV2A 1QJIA 1A85A 4DV8A 4H76A 3LJZA 2EROA 1Z3JA 1XURA 3B8ZA 2YIGA 1RM8A 4DD8A 1SLMA 3RTTA 4AUOA 3LILA 1JAOA 4QKZA 1Y8JA 1AYKA 5BPAA 1Q3AA 3HY9A 2AYKA 4H3XA 5LABA 3VI1A 2X3CA 1XFVA 2J0TA 1ZS0A 1PWVA 1GE6A 5I0LA 2WO9A 2JSDA 1PWPA 2N8RA 4R3VA 3KMEA 1O0TA 3G42A 1SU3A
chains in the Genus database with same CATH superfamily
3F19A 3LQBA 4PKSA 1SLNA 3G5CA 1MNCA 3KECA 2K9CA 1K7IA 1UEAA 1YQYA 1C8TA 1GE7A 1PWQA 4PKWA 1FM1A 4FVLA 2MLRA 3TVCA 1ZXVA 3LGPA 5BOYA 1QIBA 3DPFA 2OXWA 4XM8A 3LQ0A 2O3EA 2OY4A 2X3AA 1SATA 1HY7A 1YP1A 1KUGA 1C3IA 5D1UA 2CLTA 2JIHA 3LJGA 1JIZA 3I7GA 2FV5A 1HTDA 2D1NA 1H71P 3VTGA 1BUDA 3TSKA 1EB6A 1JH1A 4I35A 2YUFA 5B5PA 4L7AA 4H30A 2MZIA 1OS9A 4XCTA 1OS2A 1JKYA 1G12A 1R1JA 3LE9A 1I76A 4GWMA 4H2EA 1PWWA 3V96B 2TCLA 2WOAA 1HV5A 4H49A 3LKAA 3LUMA 1BKCA 5H8XA 2XS3A 4H1QA 5I43A 2A8HA 1O0QA 3EDHA 2JT5A 2CKIA 1R1HA 1CXVA 4JPAA 1ASTA 3UVCA 1UMSA 3N2VA 1XFYA 3F15A 1SMPA 3L0VA 4G9LA 5B5OA 4GF1A 1K7QA 4DF9A 1ND1A 4H84A 2YB9A 5D3CA 1Y0VA 3WV3A 5I12A 1XM5A 4HX3A 1OO9A 3B2ZA 1ROSA 1BQOA 1D8MA 3AYUA 2SRTA 1TVIA 3F18A 3DNGA 3Q2HA 4L6TA 1XUDA 2DW1A 1HFCA 2OW2A 1D5JA 1ZXCA 4AXQA 1UTTA 2W15A 1WNIA 4WF6A 4FXQA 1YOUA 1PWUA 3WV1A 2DDYA 1IAGA 1DMTA 4I03A 2OZRA 4L63A 2W0DA 3DSLA 3EDGA 1I1IP 3EHYA 1R1IA 2HU6A 1EAKA 2FV9A 2PJTA 4J4MA 3DTIA 830CA 2I47A 2V4BA 456CA 2MZHA 3TT4A 3LMCA 3L0TA 1S4BP 2D1OA 1G4KA 2MZEA 1CGEA 3O64A 3Q2GA 1R55A 4IUWA 1IAAA 2RJQA 3LIKA 3GBOA 3KRYA 4XM7A 3DL1A 2X7MA 3HY7A 4ON1A 4G0DA 3RTSA 3K7LA 3HBVP 2X3BA 2OW0A 3CKIA 3OHOA 5D1TA 4WK7A 1B3DA 1IACA 1JK3A 4GUYA 1JANA 1J7NA 4WZVA 3P1VA 1JJ9A 2L0RA 1R54A 2XS4A 1KUKA 2W13A 3EDIA 2K2GA 2QPJA 5I4OA 1IABA 3I7IA 3ZUKA 1GXDA 3HDBA 4PKTA 1IAEA 1OM6A 4PKRA 5CXAA 1BZSA 1UTZA 1D7XA 4EFSA 3KWVC 2W14A 1GKCA 3E8RA 1BIWA 1BM6A 3KEKA 1JIWP 2E2DA 1KAPP 3KHIA 3ZXHA 1D8FA 2USNA 5CZMA 3N2UA 3EWJA 3BA0A 2MLSA 1HOVA 4H82A 2AIGP 3NX7A 2OY2A 2J83A 2WO8A 1CGFA 1MMQA 2OXZA 1A86A 1I73A 4GQLA 1MMBA 3LIRA 1AF0A 1EUBA 3HDAP 5L7FA 3SHIA 1KUIA 4DPEA 3TS4A 3EHXA 1DTHA 1G05A 1B8YA 2OW9A 1KBCA 4Q1LA 4A3WA 5I3MA 1XUCA 3LK8A 1KUHA 1BQQM 5CUHA 4GR8A 3F16A 1HFSA 1IADA 1XFWA 3U1RA 3F1AA 1GE5A 1FBLA 3ELMA 3USNA 1Y93A 2DDFA 1CIZA 1OM8A 3K7NA 966CA 2O36A 3LJTA 1QICA 4XBHA 2OW1A 4GR0A 3AYKA 1ATLA 1SRPA 3DTEA 1XFUA 1QIAA 4WKEA 2ERPA 1RMZA 3AIGA 4FU4A 4JP4A 5D7WA 4JQGA 4IN9A 1CQRA 2E3XA 3F17A 1OM7A 2RJPA 2KRJA 3LEAA 1FLSA 1AKLA 4JA1A 3KMCA 1OZ9A 4GWNA 4FXYP 1ZVXA 2JNPA 4ILWD 2Y6CA 2W12A 3DPEA 1JAPA 5I2ZA 3ZVSA 3KEJA 2OI0A 1GO7P 3P24A 4L19A 1CAQA 5BOTA 3DTKA 1JAQA 1K7GA 1GO8P 4XM6A 3OHLA 2DW0A 2OVXA 2Y6DA 1QUAA 1XFXA 3O2XA 2OVZA 4AYKA 1CK7A 1ZP5A 3B92A 2ERQA 1L6JA 1OMJA 4HMAA 5D1SA 2JT6A 3DWBA 4GR3A 1XFZA 4PKUA 1BUVM 1G49A 1MMPA 1USNA 1BKCI 3EDZA 2Z2DA 4A7BA 4WKIA 4CTHA 5L79A 1BSWA 1BKCE 1G9KA 1GKDA 1QJJA 1CGLA 2DW2A 1KUFA 3LUNA 1ZTQA 3HBUP 3HYGA 1UMTA 2OXUA 5JMYA 5D2BA 1C7KA 1MMRA 1YCMA 2POJA 4PKVA 4JIJA 3MA2A 4ZR5A 4IJOA 3HB2P 4PKQA 4AIGA 3WV2A 1QJIA 1A85A 4DV8A 4H76A 3LJZA 2EROA 1Z3JA 1XURA 3B8ZA 2YIGA 1RM8A 4DD8A 1SLMA 3RTTA 1XAXA 4AUOA 3LILA 1JAOA 4QKZA 1Y8JA 1AYKA 5BPAA 1Q3AA 3HY9A 2AYKA 4H3XA 5LABA 3VI1A 2X3CA 1XFVA 2J0TA 1ZS0A 1PWVA 1GE6A 5I0LA 2WO9A 2JSDA 1PWPA 2N8RA 4R3VA 3KMEA 1O0TA 3G42A 1SU3A
chains in the Genus database with same CATH topology
3F19A 3LQBA 4PKSA 1SLNA 3G5CA 1MNCA 3KECA 2K9CA 1K7IA 1UEAA 1YQYA 1C8TA 1GE7A 1PWQA 4PKWA 1FM1A 4FVLA 2MLRA 3TVCA 1ZXVA 3LGPA 5BOYA 1QIBA 3DPFA 2OXWA 4XM8A 3LQ0A 2O3EA 2OY4A 2X3AA 1SATA 1HY7A 1YP1A 1KUGA 1C3IA 5D1UA 2CLTA 2JIHA 3LJGA 1JIZA 3I7GA 2FV5A 1HTDA 2D1NA 1H71P 3VTGA 1BUDA 3TSKA 1EB6A 1JH1A 4I35A 2YUFA 5B5PA 4L7AA 4H30A 2MZIA 1OS9A 4XCTA 1OS2A 1JKYA 1G12A 1R1JA 3LE9A 1I76A 4GWMA 4H2EA 1PWWA 3V96B 2TCLA 2WOAA 1HV5A 4H49A 3LKAA 3LUMA 1BKCA 5H8XA 2XS3A 4H1QA 5I43A 2A8HA 1O0QA 3EDHA 2JT5A 2CKIA 1R1HA 1CXVA 4JPAA 1ASTA 3UVCA 1UMSA 3N2VA 1XFYA 3F15A 1SMPA 3L0VA 4G9LA 5B5OA 4GF1A 1K7QA 4DF9A 1ND1A 4H84A 2YB9A 5D3CA 1Y0VA 3WV3A 5I12A 4HX3A 1OO9A 3B2ZA 1ROSA 1BQOA 1D8MA 3AYUA 2SRTA 3F18A 3DNGA 3Q2HA 4L6TA 1XUDA 2DW1A 1HFCA 2OW2A 1D5JA 1ZXCA 4AXQA 1UTTA 2W15A 1WNIA 4WF6A 4FXQA 1YOUA 1PWUA 3WV1A 2DDYA 1IAGA 1DMTA 4I03A 2OZRA 4L63A 2W0DA 3DSLA 3EDGA 1I1IP 3EHYA 1R1IA 2HU6A 1EAKA 2FV9A 2PJTA 4J4MA 3DTIA 830CA 2I47A 2V4BA 456CA 2MZHA 3TT4A 3LMCA 3L0TA 1S4BP 2D1OA 1G4KA 2MZEA 1CGEA 3O64A 3Q2GA 1R55A 4IUWA 1IAAA 2RJQA 3LIKA 3GBOA 3KRYA 4XM7A 3DL1A 2X7MA 3HY7A 4ON1A 4G0DA 3RTSA 3K7LA 3HBVP 2X3BA 2OW0A 3CKIA 3OHOA 5D1TA 4WK7A 1B3DA 1IACA 1JK3A 4GUYA 1JANA 1J7NA 4WZVA 3P1VA 1JJ9A 2L0RA 1R54A 2XS4A 1KUKA 2W13A 3EDIA 2K2GA 2QPJA 5I4OA 1IABA 3I7IA 3ZUKA 1GXDA 3HDBA 4PKTA 1IAEA 1OM6A 4PKRA 5CXAA 1BZSA 1UTZA 1D7XA 4EFSA 3KWVC 2W14A 1GKCA 3E8RA 1BIWA 1BM6A 3KEKA 1JIWP 2E2DA 1KAPP 3KHIA 3ZXHA 1D8FA 2USNA 5CZMA 3N2UA 3EWJA 3BA0A 2MLSA 1HOVA 4H82A 2AIGP 3NX7A 2OY2A 2J83A 2WO8A 1CGFA 1MMQA 2OXZA 1A86A 1I73A 4GQLA 1MMBA 3LIRA 1AF0A 1EUBA 3HDAP 5L7FA 3SHIA 1KUIA 4DPEA 3TS4A 3EHXA 1DTHA 1G05A 1B8YA 2OW9A 1KBCA 4Q1LA 4A3WA 5I3MA 1XUCA 3LK8A 1KUHA 1BQQM 5CUHA 4GR8A 3F16A 1HFSA 1IADA 1XFWA 3U1RA 3F1AA 1GE5A 1FBLA 3ELMA 3USNA 1Y93A 2DDFA 1CIZA 1OM8A 3K7NA 966CA 2O36A 3LJTA 1QICA 4XBHA 2OW1A 4GR0A 3AYKA 1ATLA 1SRPA 3DTEA 1XFUA 1QIAA 4WKEA 2ERPA 1RMZA 3AIGA 4FU4A 4JP4A 5D7WA 4JQGA 4IN9A 1CQRA 2E3XA 3F17A 1OM7A 2RJPA 2KRJA 3LEAA 1FLSA 1AKLA 4JA1A 3KMCA 4GWNA 4FXYP 1ZVXA 2JNPA 4ILWD 2Y6CA 2W12A 3DPEA 1JAPA 5I2ZA 3ZVSA 3KEJA 2OI0A 1GO7P 3P24A 4L19A 1CAQA 5BOTA 3DTKA 1JAQA 1K7GA 1GO8P 4XM6A 3OHLA 2DW0A 2OVXA 2Y6DA 1QUAA 1XFXA 3O2XA 2OVZA 4AYKA 1CK7A 1ZP5A 3B92A 2ERQA 1L6JA 1OMJA 4HMAA 5D1SA 2JT6A 3DWBA 4GR3A 1XFZA 4PKUA 1BUVM 1G49A 1MMPA 1USNA 1BKCI 3EDZA 2Z2DA 4A7BA 4WKIA 4CTHA 5L79A 1BSWA 1BKCE 1G9KA 1GKDA 1QJJA 1CGLA 2DW2A 1KUFA 3LUNA 1ZTQA 3HBUP 3HYGA 1UMTA 2OXUA 5JMYA 5D2BA 1C7KA 1MMRA 1YCMA 2POJA 4PKVA 4JIJA 3MA2A 4ZR5A 4IJOA 3HB2P 4PKQA 4AIGA 3WV2A 1QJIA 1A85A 4DV8A 4H76A 3LJZA 2EROA 1Z3JA 1XURA 3B8ZA 2YIGA 1RM8A 4DD8A 1SLMA 3RTTA 4AUOA 3LILA 1JAOA 4QKZA 1Y8JA 1AYKA 5BPAA 1Q3AA 3HY9A 2AYKA 4H3XA 5LABA 3VI1A 2X3CA 1XFVA 2J0TA 1ZS0A 1PWVA 1GE6A 5I0LA 2WO9A 2JSDA 1PWPA 2N8RA 4R3VA 3KMEA 1O0TA 3G42A 1SU3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3F19 A;  3LQB A;  4PKS A;  1SLN A;  3G5C A;  1MNC A;  3KEC A;  2K9C A;  1K7I A;  1UEA A;  1YQY A;  1C8T A;  1GE7 A;  1PWQ A;  4PKW A;  1FM1 A;  4FVL A;  2MLR A;  3TVC A;  1ZXV A;  3LGP A;  5BOY A;  1QIB A;  3DPF A;  2OXW A;  4XM8 A;  3LQ0 A;  2O3E A;  2OY4 A;  2X3A A;  1SAT A;  1HY7 A;  1YP1 A;  1KUG A;  1C3I A;  5D1U A;  2CLT A;  2JIH A;  3LJG A;  1JIZ A;  3I7G A;  2FV5 A;  1HTD A;  2D1N A;  1H71 P;  3VTG A;  1BUD A;  3TSK A;  1EB6 A;  1JH1 A;  4I35 A;  5B5P A;  4H30 A;  2MZI A;  1OS9 A;  4XCT A;  1OS2 A;  1JKY A;  1G12 A;  1R1J A;  3LE9 A;  1I76 A;  4GWM A;  4H2E A;  1PWW A;  3V96 B;  2TCL A;  2WOA A;  1HV5 A;  4H49 A;  3LKA A;  3LUM A;  1BKC A;  5H8X A;  2XS3 A;  4H1Q A;  5I43 A;  2A8H A;  1O0Q A;  3EDH A;  2JT5 A;  2CKI A;  1R1H A;  1CXV A;  4JPA A;  1AST A;  3UVC A;  1UMS A;  3N2V A;  1XFY A;  3F15 A;  1SMP A;  3L0V A;  4G9L A;  5B5O A;  4GF1 A;  1K7Q A;  4DF9 A;  1ND1 A;  4H84 A;  2YB9 A;  5D3C A;  1Y0V A;  3WV3 A;  5I12 A;  4HX3 A;  1OO9 A;  3B2Z A;  1ROS A;  1BQO A;  1D8M A;  3AYU A;  2SRT A;  3F18 A;  3DNG A;  3Q2H A;  4L6T A;  1XUD A;  2DW1 A;  1HFC A;  2OW2 A;  1D5J A;  1ZXC A;  4AXQ A;  1UTT A;  2W15 A;  1WNI A;  4WF6 A;  4FXQ A;  1YOU A;  1PWU A;  3WV1 A;  2DDY A;  1IAG A;  1DMT A;  4I03 A;  2OZR A;  4L63 A;  2W0D A;  3DSL A;  3EDG A;  1I1I P;  3EHY A;  1R1I A;  2HU6 A;  1EAK A;  2FV9 A;  2PJT A;  4J4M A;  830C A;  2I47 A;  2V4B A;  456C A;  2MZH A;  3TT4 A;  3LMC A;  3L0T A;  1S4B P;  2D1O A;  1G4K A;  2MZE A;  1CGE A;  3O64 A;  3Q2G A;  1R55 A;  4IUW A;  1IAA A;  2RJQ A;  3LIK A;  3GBO A;  3KRY A;  4XM7 A;  3DL1 A;  2X7M A;  3HY7 A;  4ON1 A;  4G0D A;  3RTS A;  3K7L A;  3HBV P;  2X3B A;  2OW0 A;  3CKI A;  3OHO A;  5D1T A;  4WK7 A;  1B3D A;  1IAC A;  1JK3 A;  4GUY A;  1JAN A;  1J7N A;  4WZV A;  3P1V A;  1JJ9 A;  2L0R A;  1R54 A;  2XS4 A;  1KUK A;  2W13 A;  3EDI A;  2K2G A;  2QPJ A;  5I4O A;  1IAB A;  3I7I A;  3ZUK A;  1GXD A;  3HDB A;  4PKT A;  1IAE A;  1OM6 A;  4PKR A;  5CXA A;  1BZS A;  1UTZ A;  1D7X A;  4EFS A;  3KWV C;  2W14 A;  1GKC A;  3E8R A;  1BIW A;  1BM6 A;  3KEK A;  1JIW P;  2E2D A;  1KAP P;  3KHI A;  3ZXH A;  1D8F A;  2USN A;  5CZM A;  3N2U A;  3EWJ A;  3BA0 A;  2MLS A;  1HOV A;  4H82 A;  2AIG P;  3NX7 A;  2OY2 A;  2J83 A;  2WO8 A;  1CGF A;  1MMQ A;  2OXZ A;  1A86 A;  1I73 A;  4GQL A;  1MMB A;  3LIR A;  1AF0 A;  1EUB A;  3HDA P;  5L7F A;  3SHI A;  1KUI A;  4DPE A;  3TS4 A;  3EHX A;  1DTH A;  1G05 A;  1B8Y A;  2OW9 A;  1KBC A;  4Q1L A;  4A3W A;  5I3M A;  1XUC A;  3LK8 A;  1KUH A;  1BQQ M;  5CUH A;  4GR8 A;  3F16 A;  1HFS A;  1IAD A;  1XFW A;  3U1R A;  3F1A A;  1GE5 A;  1FBL A;  3ELM A;  3USN A;  1Y93 A;  2DDF A;  1CIZ A;  1OM8 A;  3K7N A;  966C A;  2O36 A;  3LJT A;  1QIC A;  4XBH A;  2OW1 A;  4GR0 A;  3AYK A;  1ATL A;  1SRP A;  1XFU A;  1QIA A;  4WKE A;  2ERP A;  1RMZ A;  3AIG A;  4FU4 A;  4JP4 A;  5D7W A;  4JQG A;  4IN9 A;  1CQR A;  2E3X A;  3F17 A;  1OM7 A;  2RJP A;  2KRJ A;  3LEA A;  1FLS A;  1AKL A;  4JA1 A;  3KMC A;  4GWN A;  4FXY P;  1ZVX A;  2JNP A;  4ILW D;  2Y6C A;  2W12 A;  3DPE A;  1JAP A;  5I2Z A;  3ZVS A;  3KEJ A;  2OI0 A;  1GO7 P;  3P24 A;  4L19 A;  1CAQ A;  5BOT A;  1JAQ A;  1K7G A;  1GO8 P;  4XM6 A;  3OHL A;  2DW0 A;  2OVX A;  2Y6D A;  1QUA A;  1XFX A;  3O2X A;  2OVZ A;  4AYK A;  1CK7 A;  1ZP5 A;  3B92 A;  2ERQ A;  1L6J A;  1OMJ A;  4HMA A;  5D1S A;  2JT6 A;  3DWB A;  4GR3 A;  1XFZ A;  4PKU A;  1BUV M;  1G49 A;  1MMP A;  1USN A;  1BKC I;  3EDZ A;  2Z2D A;  4A7B A;  4WKI A;  4CTH A;  5L79 A;  1BSW A;  1BKC E;  1G9K A;  1GKD A;  1QJJ A;  1CGL A;  2DW2 A;  1KUF A;  3LUN A;  1ZTQ A;  3HBU P;  3HYG A;  1UMT A;  2OXU A;  5JMY A;  5D2B A;  1C7K A;  1MMR A;  1YCM A;  2POJ A;  4PKV A;  4JIJ A;  3MA2 A;  4ZR5 A;  4IJO A;  3HB2 P;  4PKQ A;  4AIG A;  3WV2 A;  1QJI A;  1A85 A;  4DV8 A;  4H76 A;  3LJZ A;  2ERO A;  1Z3J A;  1XUR A;  3B8Z A;  2YIG A;  1RM8 A;  4DD8 A;  1SLM A;  3RTT A;  4AUO A;  3LIL A;  1JAO A;  4QKZ A;  1Y8J A;  1AYK A;  5BPA A;  1Q3A A;  3HY9 A;  2AYK A;  4H3X A;  5LAB A;  3VI1 A;  2X3C A;  1XFV A;  2J0T A;  1ZS0 A;  1PWV A;  1GE6 A;  5I0L A;  2WO9 A;  2JSD A;  1PWP A;  2N8R A;  4R3V A;  3KME A;  1O0T A;  3G42 A;  1SU3 A; 
#chains in the Genus database with same CATH topology
 3F19 A;  3LQB A;  4PKS A;  1SLN A;  3G5C A;  1MNC A;  3KEC A;  2K9C A;  1K7I A;  1UEA A;  1YQY A;  1C8T A;  1GE7 A;  1PWQ A;  4PKW A;  1FM1 A;  4FVL A;  2MLR A;  3TVC A;  1ZXV A;  3LGP A;  5BOY A;  1QIB A;  3DPF A;  2OXW A;  4XM8 A;  3LQ0 A;  2O3E A;  2OY4 A;  2X3A A;  1SAT A;  1HY7 A;  1YP1 A;  1KUG A;  1C3I A;  5D1U A;  2CLT A;  2JIH A;  3LJG A;  1JIZ A;  3I7G A;  2FV5 A;  1HTD A;  2D1N A;  1H71 P;  3VTG A;  1BUD A;  3TSK A;  1EB6 A;  1JH1 A;  4I35 A;  2YUF A;  5B5P A;  4L7A A;  4H30 A;  2MZI A;  1OS9 A;  4XCT A;  1OS2 A;  1JKY A;  1G12 A;  1R1J A;  3LE9 A;  1I76 A;  4GWM A;  4H2E A;  1PWW A;  3V96 B;  2TCL A;  2WOA A;  1HV5 A;  4H49 A;  3LKA A;  3LUM A;  1BKC A;  5H8X A;  2XS3 A;  4H1Q A;  5I43 A;  2A8H A;  1O0Q A;  3EDH A;  2JT5 A;  2CKI A;  1R1H A;  1CXV A;  4JPA A;  1AST A;  3UVC A;  1UMS A;  3N2V A;  1XFY A;  3F15 A;  1SMP A;  3L0V A;  4G9L A;  5B5O A;  4GF1 A;  1K7Q A;  4DF9 A;  1ND1 A;  4H84 A;  2YB9 A;  5D3C A;  1Y0V A;  3WV3 A;  5I12 A;  1XM5 A;  4HX3 A;  1OO9 A;  3B2Z A;  1ROS A;  1BQO A;  1D8M A;  3AYU A;  2SRT A;  1TVI A;  3F18 A;  3DNG A;  3Q2H A;  4L6T A;  1XUD A;  2DW1 A;  1HFC A;  2OW2 A;  1D5J A;  1ZXC A;  4AXQ A;  1UTT A;  2W15 A;  1WNI A;  4WF6 A;  4FXQ A;  1YOU A;  1PWU A;  3WV1 A;  2DDY A;  1IAG A;  1DMT A;  4I03 A;  2OZR A;  4L63 A;  2W0D A;  3DSL A;  3EDG A;  1I1I P;  3EHY A;  1R1I A;  2HU6 A;  1EAK A;  2FV9 A;  2PJT A;  4J4M A;  3DTI A;  830C A;  2I47 A;  2V4B A;  456C A;  2MZH A;  3TT4 A;  3LMC A;  3L0T A;  1S4B P;  2D1O A;  1G4K A;  2MZE A;  1CGE A;  3O64 A;  3Q2G A;  1R55 A;  4IUW A;  1IAA A;  2RJQ A;  3LIK A;  3GBO A;  3KRY A;  4XM7 A;  3DL1 A;  2X7M A;  3HY7 A;  4ON1 A;  4G0D A;  3RTS A;  3K7L A;  3HBV P;  2X3B A;  2OW0 A;  3CKI A;  3OHO A;  5D1T A;  4WK7 A;  1B3D A;  1IAC A;  1JK3 A;  4GUY A;  1JAN A;  1J7N A;  4WZV A;  3P1V A;  1JJ9 A;  2L0R A;  1R54 A;  2XS4 A;  1KUK A;  2W13 A;  3EDI A;  2K2G A;  2QPJ A;  5I4O A;  1IAB A;  3I7I A;  3ZUK A;  1GXD A;  3HDB A;  4PKT A;  1IAE A;  1OM6 A;  4PKR A;  5CXA A;  1BZS A;  1UTZ A;  1D7X A;  4EFS A;  3KWV C;  2W14 A;  1GKC A;  3E8R A;  1BIW A;  1BM6 A;  3KEK A;  1JIW P;  2E2D A;  1KAP P;  3KHI A;  3ZXH A;  1D8F A;  2USN A;  5CZM A;  3N2U A;  3EWJ A;  3BA0 A;  2MLS A;  1HOV A;  4H82 A;  2AIG P;  3NX7 A;  2OY2 A;  2J83 A;  2WO8 A;  1CGF A;  1MMQ A;  2OXZ A;  1A86 A;  1I73 A;  4GQL A;  1MMB A;  3LIR A;  1AF0 A;  1EUB A;  3HDA P;  5L7F A;  3SHI A;  1KUI A;  4DPE A;  3TS4 A;  3EHX A;  1DTH A;  1G05 A;  1B8Y A;  2OW9 A;  1KBC A;  4Q1L A;  4A3W A;  5I3M A;  1XUC A;  3LK8 A;  1KUH A;  1BQQ M;  5CUH A;  4GR8 A;  3F16 A;  1HFS A;  1IAD A;  1XFW A;  3U1R A;  3F1A A;  1GE5 A;  1FBL A;  3ELM A;  3USN A;  1Y93 A;  2DDF A;  1CIZ A;  1OM8 A;  3K7N A;  966C A;  2O36 A;  3LJT A;  1QIC A;  4XBH A;  2OW1 A;  4GR0 A;  3AYK A;  1ATL A;  1SRP A;  3DTE A;  1XFU A;  1QIA A;  4WKE A;  2ERP A;  1RMZ A;  3AIG A;  4FU4 A;  4JP4 A;  5D7W A;  4JQG A;  4IN9 A;  1CQR A;  2E3X A;  3F17 A;  1OM7 A;  2RJP A;  2KRJ A;  3LEA A;  1FLS A;  1AKL A;  4JA1 A;  3KMC A;  1OZ9 A;  4GWN A;  4FXY P;  1ZVX A;  2JNP A;  4ILW D;  2Y6C A;  2W12 A;  3DPE A;  1JAP A;  5I2Z A;  3ZVS A;  3KEJ A;  2OI0 A;  1GO7 P;  3P24 A;  4L19 A;  1CAQ A;  5BOT A;  3DTK A;  1JAQ A;  1K7G A;  1GO8 P;  4XM6 A;  3OHL A;  2DW0 A;  2OVX A;  2Y6D A;  1QUA A;  1XFX A;  3O2X A;  2OVZ A;  4AYK A;  1CK7 A;  1ZP5 A;  3B92 A;  2ERQ A;  1L6J A;  1OMJ A;  4HMA A;  5D1S A;  2JT6 A;  3DWB A;  4GR3 A;  1XFZ A;  4PKU A;  1BUV M;  1G49 A;  1MMP A;  1USN A;  1BKC I;  3EDZ A;  2Z2D A;  4A7B A;  4WKI A;  4CTH A;  5L79 A;  1BSW A;  1BKC E;  1G9K A;  1GKD A;  1QJJ A;  1CGL A;  2DW2 A;  1KUF A;  3LUN A;  1ZTQ A;  3HBU P;  3HYG A;  1UMT A;  2OXU A;  5JMY A;  5D2B A;  1C7K A;  1MMR A;  1YCM A;  2POJ A;  4PKV A;  4JIJ A;  3MA2 A;  4ZR5 A;  4IJO A;  3HB2 P;  4PKQ A;  4AIG A;  3WV2 A;  1QJI A;  1A85 A;  4DV8 A;  4H76 A;  3LJZ A;  2ERO A;  1Z3J A;  1XUR A;  3B8Z A;  2YIG A;  1RM8 A;  4DD8 A;  1SLM A;  3RTT A;  1XAX A;  4AUO A;  3LIL A;  1JAO A;  4QKZ A;  1Y8J A;  1AYK A;  5BPA A;  1Q3A A;  3HY9 A;  2AYK A;  4H3X A;  5LAB A;  3VI1 A;  2X3C A;  1XFV A;  2J0T A;  1ZS0 A;  1PWV A;  1GE6 A;  5I0L A;  2WO9 A;  2JSD A;  1PWP A;  2N8R A;  4R3V A;  3KME A;  1O0T A;  3G42 A;  1SU3 A; 
#chains in the Genus database with same CATH homology
 3F19 A;  3LQB A;  4PKS A;  1SLN A;  3G5C A;  1MNC A;  3KEC A;  2K9C A;  1K7I A;  1UEA A;  1YQY A;  1C8T A;  1GE7 A;  1PWQ A;  4PKW A;  1FM1 A;  4FVL A;  2MLR A;  3TVC A;  1ZXV A;  3LGP A;  5BOY A;  1QIB A;  3DPF A;  2OXW A;  4XM8 A;  3LQ0 A;  2O3E A;  2OY4 A;  2X3A A;  1SAT A;  1HY7 A;  1YP1 A;  1KUG A;  1C3I A;  5D1U A;  2CLT A;  2JIH A;  3LJG A;  1JIZ A;  3I7G A;  2FV5 A;  1HTD A;  2D1N A;  1H71 P;  3VTG A;  1BUD A;  3TSK A;  1EB6 A;  1JH1 A;  4I35 A;  2YUF A;  5B5P A;  4L7A A;  4H30 A;  2MZI A;  1OS9 A;  4XCT A;  1OS2 A;  1JKY A;  1G12 A;  1R1J A;  3LE9 A;  1I76 A;  4GWM A;  4H2E A;  1PWW A;  3V96 B;  2TCL A;  2WOA A;  1HV5 A;  4H49 A;  3LKA A;  3LUM A;  1BKC A;  5H8X A;  2XS3 A;  4H1Q A;  5I43 A;  2A8H A;  1O0Q A;  3EDH A;  2JT5 A;  2CKI A;  1R1H A;  1CXV A;  4JPA A;  1AST A;  3UVC A;  1UMS A;  3N2V A;  1XFY A;  3F15 A;  1SMP A;  3L0V A;  4G9L A;  5B5O A;  4GF1 A;  1K7Q A;  4DF9 A;  1ND1 A;  4H84 A;  2YB9 A;  5D3C A;  1Y0V A;  3WV3 A;  5I12 A;  4HX3 A;  1OO9 A;  3B2Z A;  1ROS A;  1BQO A;  1D8M A;  3AYU A;  2SRT A;  3F18 A;  3DNG A;  3Q2H A;  4L6T A;  1XUD A;  2DW1 A;  1HFC A;  2OW2 A;  1D5J A;  1ZXC A;  4AXQ A;  1UTT A;  2W15 A;  1WNI A;  4WF6 A;  4FXQ A;  1YOU A;  1PWU A;  3WV1 A;  2DDY A;  1IAG A;  1DMT A;  4I03 A;  2OZR A;  4L63 A;  2W0D A;  3DSL A;  3EDG A;  1I1I P;  3EHY A;  1R1I A;  2HU6 A;  1EAK A;  2FV9 A;  2PJT A;  4J4M A;  3DTI A;  830C A;  2I47 A;  2V4B A;  456C A;  2MZH A;  3TT4 A;  3LMC A;  3L0T A;  1S4B P;  2D1O A;  1G4K A;  2MZE A;  1CGE A;  3O64 A;  3Q2G A;  1R55 A;  4IUW A;  1IAA A;  2RJQ A;  3LIK A;  3GBO A;  3KRY A;  4XM7 A;  3DL1 A;  2X7M A;  3HY7 A;  4ON1 A;  4G0D A;  3RTS A;  3K7L A;  3HBV P;  2X3B A;  2OW0 A;  3CKI A;  3OHO A;  5D1T A;  4WK7 A;  1B3D A;  1IAC A;  1JK3 A;  4GUY A;  1JAN A;  1J7N A;  4WZV A;  3P1V A;  1JJ9 A;  2L0R A;  1R54 A;  2XS4 A;  1KUK A;  2W13 A;  3EDI A;  2K2G A;  2QPJ A;  5I4O A;  1IAB A;  3I7I A;  3ZUK A;  1GXD A;  3HDB A;  4PKT A;  1IAE A;  1OM6 A;  4PKR A;  5CXA A;  1BZS A;  1UTZ A;  1D7X A;  4EFS A;  3KWV C;  2W14 A;  1GKC A;  3E8R A;  1BIW A;  1BM6 A;  3KEK A;  1JIW P;  2E2D A;  1KAP P;  3KHI A;  3ZXH A;  1D8F A;  2USN A;  5CZM A;  3N2U A;  3EWJ A;  3BA0 A;  2MLS A;  1HOV A;  4H82 A;  2AIG P;  3NX7 A;  2OY2 A;  2J83 A;  2WO8 A;  1CGF A;  1MMQ A;  2OXZ A;  1A86 A;  1I73 A;  4GQL A;  1MMB A;  3LIR A;  1AF0 A;  1EUB A;  3HDA P;  5L7F A;  3SHI A;  1KUI A;  4DPE A;  3TS4 A;  3EHX A;  1DTH A;  1G05 A;  1B8Y A;  2OW9 A;  1KBC A;  4Q1L A;  4A3W A;  5I3M A;  1XUC A;  3LK8 A;  1KUH A;  1BQQ M;  5CUH A;  4GR8 A;  3F16 A;  1HFS A;  1IAD A;  1XFW A;  3U1R A;  3F1A A;  1GE5 A;  1FBL A;  3ELM A;  3USN A;  1Y93 A;  2DDF A;  1CIZ A;  1OM8 A;  3K7N A;  966C A;  2O36 A;  3LJT A;  1QIC A;  4XBH A;  2OW1 A;  4GR0 A;  3AYK A;  1ATL A;  1SRP A;  3DTE A;  1XFU A;  1QIA A;  4WKE A;  2ERP A;  1RMZ A;  3AIG A;  4FU4 A;  4JP4 A;  5D7W A;  4JQG A;  4IN9 A;  1CQR A;  2E3X A;  3F17 A;  1OM7 A;  2RJP A;  2KRJ A;  3LEA A;  1FLS A;  1AKL A;  4JA1 A;  3KMC A;  4GWN A;  4FXY P;  1ZVX A;  2JNP A;  4ILW D;  2Y6C A;  2W12 A;  3DPE A;  1JAP A;  5I2Z A;  3ZVS A;  3KEJ A;  2OI0 A;  1GO7 P;  3P24 A;  4L19 A;  1CAQ A;  5BOT A;  3DTK A;  1JAQ A;  1K7G A;  1GO8 P;  4XM6 A;  3OHL A;  2DW0 A;  2OVX A;  2Y6D A;  1QUA A;  1XFX A;  3O2X A;  2OVZ A;  4AYK A;  1CK7 A;  1ZP5 A;  3B92 A;  2ERQ A;  1L6J A;  1OMJ A;  4HMA A;  5D1S A;  2JT6 A;  3DWB A;  4GR3 A;  1XFZ A;  4PKU A;  1BUV M;  1G49 A;  1MMP A;  1USN A;  1BKC I;  3EDZ A;  2Z2D A;  4A7B A;  4WKI A;  4CTH A;  5L79 A;  1BSW A;  1BKC E;  1G9K A;  1GKD A;  1QJJ A;  1CGL A;  2DW2 A;  1KUF A;  3LUN A;  1ZTQ A;  3HBU P;  3HYG A;  1UMT A;  2OXU A;  5JMY A;  5D2B A;  1C7K A;  1MMR A;  1YCM A;  2POJ A;  4PKV A;  4JIJ A;  3MA2 A;  4ZR5 A;  4IJO A;  3HB2 P;  4PKQ A;  4AIG A;  3WV2 A;  1QJI A;  1A85 A;  4DV8 A;  4H76 A;  3LJZ A;  2ERO A;  1Z3J A;  1XUR A;  3B8Z A;  2YIG A;  1RM8 A;  4DD8 A;  1SLM A;  3RTT A;  4AUO A;  3LIL A;  1JAO A;  4QKZ A;  1Y8J A;  1AYK A;  5BPA A;  1Q3A A;  3HY9 A;  2AYK A;  4H3X A;  5LAB A;  3VI1 A;  2X3C A;  1XFV A;  2J0T A;  1ZS0 A;  1PWV A;  1GE6 A;  5I0L A;  2WO9 A;  2JSD A;  1PWP A;  2N8R A;  4R3V A;  3KME A;  1O0T A;  3G42 A;  1SU3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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