4WK7A

Crystal structure of human adamts-4 in complex with inhibitor (compound 1, 2-(4-chlorophenoxy)-n-{[(4r)-4-methyl-2,5-dioxoimidazolidin-4-yl]methyl} acetamide)
Total Genus 71
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
216
structure length
209
Chain Sequence
SRFVETLVVADDKMAAFHGAGLKRYLLTVMAAAAKAFKHPSIRNPVSLVVTRLVILGPQVGPSAAQTLRSFCAWQRGLNTPEDSDPDHFDTAILFTRQDLCGVSTCDTLGMADVGTVCDPARSCAIVEDDGLQSAFTAAHELGHVFNMLHDNSKPCISLNGPLSRHVMAPVMAHVDPEEPWSPCSARFITDFLDNGYGHCLLDKPEAPL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
publication title Identification of potent and selective hydantoin inhibitors of aggrecanase-1 and aggrecanase-2 that are efficacious in both chemical and surgical models of osteoarthritis.
pubmed doi rcsb
molecule keywords A disintegrin and metalloproteinase with thrombospondin moti
total genus 71
structure length 209
sequence length 216
ec nomenclature ec 3.4.24.82: ADAMTS-4 endopeptidase.
pdb deposition date 2014-10-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01421 Reprolysin Reprolysin (M12B) family zinc metalloprotease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 4wk7A00
1BZSA 2JSDA 1MMBA 2DDFA 1OM8A 1O0QA 1C7KA 1EB6A 966CA 4PKVA 1HOVA 1OS2A 2A8HA 4IJOA 1C8TA 1USNA 4PKWA 3KMCA 3F18A 1SLNA 1B8YA 3I7IA 4GQLA 5CUHA 2Y6CA 1GKCA 1SATA 5B5PA 1PWVA 2CLTA 2E3XA 3B92A 1HY7A 1Y0VA 3TVCA 3B8ZA 1CAQA 4AYKA 1GKDA 1BUDA 4H76A 3LQBA 1FLSA 2MLRA 3DNGA 3KRYA 2OVZA 4FU4A 4J4MA 1ZXCA 5I4OA 5BOTA 3MA2A 4GWNA 4HMAA 1I73A 3OHLA 5D1SA 3BA0A 1CGFA 1A85A 4WZVA 1OO9A 2W14A 5I3MA 1XFWA 3TSKA 3NX7A 2POJA 1YOUA 1YQYA 1PWWA 4PKRA 1K7GA 1AF0A 3LEAA 3OHOA 4FXYP 1ZP5A 4EFSA 3HDBA 1O0TA 1XURA 3F1AA 3AYUA 2AIGP 3EHXA 2OZRA 1IACA 3LE9A 2O36A 4WF6A 2TCLA 2X3CA 3ZUKA 1DTHA 2OXUA 3EDIA 1BKCE 1CGLA 3E8RA 3I7GA 1D8FA 3RTTA 3P24A 5I2ZA 3AYKA 2YB9A 3LUNA 1IAGA 1S4BP 2EROA 4WKIA 2W13A 4JA1A 3DWBA 3VTGA 3LIRA 3LJGA 1UTTA 1ZTQA 1K7IA 1MMQA 1AYKA 2OXWA 4AUOA 1L6JA 1AKLA 2OW0A 4QKZA 1UMTA 3V96B 4GR8A 2OW9A 4WKEA 4XM6A 1JH1A 1I76A 1SRPA 1SU3A 2FV5A 2JT6A 4GR3A 2ERPA 5CXAA 1Y8JA 5LABA 2MZHA 3ZXHA 1RMZA 1GO8P 1ASTA 1QICA 1ND1A 2WO9A 1IABA 2JIHA 2OXZA 2Y6DA 5L7FA 2J83A 4CTHA 3HDAP 4PKQA 4XM7A 2OW1A 2DDYA 4H84A 4ZR5A 3P1VA 1FBLA 3HB2P 3LK8A 2K2GA 5D7WA 3F19A 4G0DA 2JT5A 3KEJA 4DD8A 1QIBA 2XS3A 1IADA 1G05A 3HY7A 3O2XA 4WK7A 1G12A 5BOYA 1KUFA 830CA 3K7LA 3LILA 456CA 1Z3JA 1BKCA 2V4BA 3ZVSA 4GF1A 3ELMA 1MMRA 5JMYA 3DPEA 3F16A 1CQRA 5L79A 1R55A 4H49A 3N2UA 4AXQA 2OI0A 1KUIA 1MMPA 1JAPA 4AIGA 3UVCA 1GE7A 1KUHA 3LMCA 2ERQA 3DSLA 1HTDA 1JKYA 2SRTA 4GR0A 1HFCA 4HX3A 3HY9A 4I03A 1XFZA 4R3VA 1DMTA 3RTSA 1MNCA 3LGPA 1CK7A 2QPJA 1FM1A 3F17A 2MZEA 1H71P 1QIAA 2WO8A 3KHIA 3WV1A 1UTZA 3L0VA 4FXQA 2DW0A 5I12A 2CKIA 3KECA 3GBOA 4JPAA 2X3AA 2KRJA 3LUMA 2USNA 4XBHA 3WV3A 2X7MA 5B5OA 1R1JA 1HV5A 5BPAA 1GO7P 2N8RA 4XM8A 1R54A 2K9CA 2D1OA 4L19A 1YCMA 1A86A 3KEKA 3EDZA 4DV8A 2L0RA 1XFVA 2W0DA 1BSWA 3TS4A 4GUYA 3LJZA 4IN9A 1EUBA 3U1RA 1SLMA 1JK3A 1KAPP 1RM8A 4H2EA 4L6TA 3L0TA 4PKTA 1QJJA 1IAAA 1JANA 1Q3AA 1Y93A 1ATLA 2AYKA 4H3XA 2W15A 1J7NA 1JJ9A 1JIWP 2YIGA 5D2BA 3WV2A 1BIWA 1JAOA 2J0TA 4XCTA 2HU6A 1CGEA 1BQQM 4GWMA 1ZXVA 5I43A 4DF9A 2RJPA 1QUAA 3LIKA 2E2DA 1XFXA 1K7QA 1OM7A 3F15A 2JNPA 1KBCA 1OS9A 4DPEA 1KUGA 3G42A 2OVXA 3TT4A 3HYGA 4JP4A 4JIJA 1G49A 2WOAA 3KWVC 1GE5A 1WNIA 3LKAA 4PKSA 2D1NA 4H30A 3USNA 1QJIA 2W12A 3O64A 1BQOA 4Q1LA 1EAKA 5D1UA 3HBVP 2FV9A 1PWUA 3SHIA 3EDHA 2Z2DA 3B2ZA 4H82A 3EWJA 1SMPA 1OMJA 4JQGA 4A7BA 1G4KA 5CZMA 5H8XA 3LQ0A 2DW2A 1UMSA 2RJQA 1XUCA 1ZS0A 3LJTA 4A3WA 5I0LA 3G5CA 3VI1A 3Q2HA 4ON1A 1G9KA 3AIGA 5D3CA 2OW2A 1BKCI 3Q2GA 2XS4A 5D1TA 3EDGA 1C3IA 1CXVA 3DPFA 1PWQA 1I1IP 1R1HA 1KUKA 1XFUA 1BM6A 3CKIA 1JAQA 2I47A 1D8MA 1D5JA 1GXDA 1XUDA 1GE6A 1ROSA 1OM6A 1JIZA 1UEAA 1HFSA 4I35A 1IAEA 4IUWA 4FVLA 4G9LA 2O3EA 3EHYA 2PJTA 1D7XA 1R1IA 4L63A 2X3BA 1YP1A 4PKUA 3K7NA 3KMEA 1XFYA 1B3DA 1PWPA 2MLSA 1CIZA 3N2VA 2MZIA 2OY4A 2OY2A 1ZVXA 2DW1A 3HBUP 4H1QA 3DL1A 1BUVM 4ILWD
chains in the Genus database with same CATH superfamily
1BZSA 2JSDA 1MMBA 2DDFA 1OM8A 1O0QA 1C7KA 1EB6A 966CA 4PKVA 1HOVA 1OS2A 2A8HA 4IJOA 1C8TA 1USNA 4PKWA 3KMCA 3F18A 1SLNA 1B8YA 3I7IA 4GQLA 5CUHA 2Y6CA 1GKCA 1SATA 5B5PA 1PWVA 2CLTA 2E3XA 3B92A 1HY7A 1Y0VA 3TVCA 3B8ZA 1CAQA 4AYKA 1GKDA 1BUDA 4H76A 3LQBA 1FLSA 2MLRA 3DNGA 3KRYA 2OVZA 4FU4A 4J4MA 1ZXCA 5I4OA 5BOTA 3MA2A 4GWNA 4HMAA 1I73A 3OHLA 5D1SA 3BA0A 1CGFA 1A85A 4WZVA 1OO9A 2W14A 5I3MA 1XFWA 3TSKA 3NX7A 2POJA 1YOUA 1YQYA 1PWWA 4PKRA 1K7GA 1AF0A 3LEAA 3OHOA 4FXYP 1ZP5A 4EFSA 3HDBA 1O0TA 1XURA 3F1AA 3AYUA 2AIGP 3EHXA 2OZRA 1IACA 3LE9A 2O36A 4WF6A 2TCLA 2X3CA 3ZUKA 1DTHA 2OXUA 3EDIA 1BKCE 1CGLA 3E8RA 3I7GA 1D8FA 3RTTA 3P24A 5I2ZA 3AYKA 2YB9A 3LUNA 1IAGA 1S4BP 2EROA 4WKIA 2W13A 4JA1A 3DWBA 3VTGA 3LIRA 3LJGA 1UTTA 1ZTQA 1K7IA 1MMQA 1AYKA 2OXWA 4AUOA 1L6JA 1AKLA 2OW0A 4QKZA 1UMTA 3V96B 4GR8A 2OW9A 4WKEA 4XM6A 1JH1A 1I76A 1SRPA 1SU3A 2FV5A 2JT6A 4GR3A 2ERPA 5CXAA 1Y8JA 5LABA 2MZHA 3ZXHA 1RMZA 1GO8P 3DTEA 1ASTA 1QICA 1ND1A 2WO9A 1IABA 2JIHA 2OXZA 2Y6DA 5L7FA 2J83A 4CTHA 3HDAP 4PKQA 4XM7A 2OW1A 2DDYA 4H84A 4ZR5A 3P1VA 1FBLA 3HB2P 3LK8A 2K2GA 5D7WA 3F19A 4G0DA 2JT5A 3KEJA 4DD8A 1QIBA 2XS3A 1IADA 1G05A 3HY7A 3O2XA 4WK7A 1G12A 5BOYA 1KUFA 830CA 3K7LA 3LILA 456CA 1TVIA 1Z3JA 1BKCA 2V4BA 3ZVSA 4GF1A 3ELMA 1MMRA 5JMYA 3DPEA 3F16A 1CQRA 5L79A 1R55A 4H49A 3N2UA 4AXQA 2OI0A 1KUIA 1MMPA 1JAPA 4AIGA 3UVCA 1GE7A 1KUHA 3DSLA 2ERQA 3LMCA 1HTDA 1JKYA 2SRTA 4GR0A 1HFCA 4HX3A 3HY9A 4I03A 1XFZA 4R3VA 1DMTA 3RTSA 4L7AA 1MNCA 3LGPA 1CK7A 2QPJA 1FM1A 3F17A 2MZEA 1H71P 1QIAA 2WO8A 3KHIA 3WV1A 1UTZA 3L0VA 4FXQA 2DW0A 5I12A 2CKIA 3KECA 3GBOA 4JPAA 2X3AA 2KRJA 3LUMA 2USNA 4XBHA 3WV3A 2X7MA 5B5OA 1R1JA 1HV5A 5BPAA 1GO7P 2N8RA 4XM8A 1R54A 2K9CA 2D1OA 4L19A 1YCMA 1A86A 3KEKA 3EDZA 4DV8A 2L0RA 1XFVA 2W0DA 1BSWA 3TS4A 4GUYA 3LJZA 4IN9A 1EUBA 3U1RA 1SLMA 1JK3A 1KAPP 1RM8A 4H2EA 4L6TA 3L0TA 4PKTA 1QJJA 1IAAA 1JANA 1Q3AA 1Y93A 1ATLA 2AYKA 4H3XA 2W15A 1J7NA 1JJ9A 1JIWP 2YIGA 5D2BA 3WV2A 1BIWA 1JAOA 2J0TA 4XCTA 2HU6A 1CGEA 1BQQM 2YUFA 4GWMA 1ZXVA 5I43A 4DF9A 2RJPA 1QUAA 3LIKA 2E2DA 1XFXA 1K7QA 1OM7A 3F15A 2JNPA 1KBCA 1OS9A 4DPEA 1KUGA 3G42A 2OVXA 3TT4A 3HYGA 4JP4A 4JIJA 1G49A 2WOAA 3KWVC 1GE5A 1WNIA 3LKAA 4PKSA 2D1NA 4H30A 3USNA 1QJIA 2W12A 3O64A 1BQOA 4Q1LA 1EAKA 5D1UA 3HBVP 2FV9A 1PWUA 3SHIA 1XAXA 3EDHA 2Z2DA 3B2ZA 4H82A 3EWJA 1SMPA 1OMJA 4JQGA 4A7BA 1G4KA 5CZMA 5H8XA 3LQ0A 2DW2A 1UMSA 2RJQA 1XUCA 1ZS0A 3LJTA 4A3WA 5I0LA 3G5CA 3VI1A 3Q2HA 4ON1A 1G9KA 3AIGA 5D3CA 2OW2A 1BKCI 3Q2GA 1OZ9A 2XS4A 5D1TA 3EDGA 1C3IA 3DTIA 1CXVA 3DPFA 1PWQA 1I1IP 1R1HA 1KUKA 1XFUA 1BM6A 3CKIA 1JAQA 2I47A 1D8MA 1D5JA 1GXDA 1XUDA 1GE6A 1ROSA 1OM6A 1JIZA 1UEAA 1HFSA 4I35A 1IAEA 4IUWA 4FVLA 4G9LA 2O3EA 3EHYA 2PJTA 1D7XA 1R1IA 4L63A 2X3BA 1YP1A 3DTKA 4PKUA 3K7NA 3KMEA 1XFYA 1B3DA 1PWPA 2MLSA 1CIZA 3N2VA 2MZIA 2OY4A 2OY2A 1ZVXA 2DW1A 3HBUP 4H1QA 1XM5A 3DL1A 1BUVM 4ILWD
chains in the Genus database with same CATH topology
1BZSA 2JSDA 1MMBA 2DDFA 1OM8A 1O0QA 1C7KA 1EB6A 966CA 4PKVA 1HOVA 1OS2A 2A8HA 4IJOA 1C8TA 1USNA 4PKWA 3KMCA 3F18A 1SLNA 1B8YA 3I7IA 4GQLA 5CUHA 2Y6CA 1GKCA 1SATA 5B5PA 1PWVA 2CLTA 2E3XA 3B92A 1HY7A 1Y0VA 3TVCA 3B8ZA 1CAQA 4AYKA 1GKDA 1BUDA 4H76A 3LQBA 1FLSA 2MLRA 3DNGA 3KRYA 2OVZA 4FU4A 4J4MA 1ZXCA 5I4OA 5BOTA 3MA2A 4GWNA 4HMAA 1I73A 3OHLA 5D1SA 3BA0A 1CGFA 1A85A 4WZVA 1OO9A 2W14A 5I3MA 1XFWA 3TSKA 3NX7A 2POJA 1YOUA 1YQYA 1PWWA 4PKRA 1K7GA 1AF0A 3LEAA 3OHOA 4FXYP 1ZP5A 4EFSA 3HDBA 1O0TA 1XURA 3F1AA 3AYUA 2AIGP 3EHXA 2OZRA 1IACA 3LE9A 2O36A 4WF6A 2TCLA 2X3CA 3ZUKA 1DTHA 2OXUA 3EDIA 1BKCE 1CGLA 3E8RA 3I7GA 1D8FA 3RTTA 3P24A 5I2ZA 3AYKA 2YB9A 3LUNA 1IAGA 1S4BP 2EROA 4WKIA 2W13A 4JA1A 3DWBA 3VTGA 3LIRA 3LJGA 1UTTA 1ZTQA 1K7IA 1MMQA 1AYKA 2OXWA 4AUOA 1L6JA 1AKLA 2OW0A 4QKZA 1UMTA 3V96B 4GR8A 2OW9A 4WKEA 4XM6A 1JH1A 1I76A 1SRPA 1SU3A 2FV5A 2JT6A 4GR3A 2ERPA 5CXAA 1Y8JA 5LABA 2MZHA 3ZXHA 1RMZA 1GO8P 3DTEA 1ASTA 1QICA 1ND1A 2WO9A 1IABA 2JIHA 2OXZA 2Y6DA 5L7FA 2J83A 4CTHA 3HDAP 4PKQA 4XM7A 2OW1A 2DDYA 4H84A 4ZR5A 3P1VA 1FBLA 3HB2P 3LK8A 2K2GA 5D7WA 3F19A 4G0DA 2JT5A 3KEJA 4DD8A 1QIBA 2XS3A 1IADA 1G05A 3HY7A 3O2XA 4WK7A 1G12A 5BOYA 1KUFA 830CA 3K7LA 3LILA 456CA 1Z3JA 1BKCA 2V4BA 3ZVSA 4GF1A 3ELMA 1MMRA 5JMYA 3DPEA 3F16A 1CQRA 5L79A 1R55A 4H49A 3N2UA 4AXQA 2OI0A 1KUIA 1MMPA 1JAPA 4AIGA 3UVCA 1GE7A 1KUHA 3DSLA 2ERQA 3LMCA 1HTDA 1JKYA 2SRTA 4GR0A 1HFCA 4HX3A 3HY9A 4I03A 1XFZA 4R3VA 1DMTA 3RTSA 4L7AA 1MNCA 3LGPA 1CK7A 2QPJA 1FM1A 3F17A 2MZEA 1H71P 1QIAA 2WO8A 3KHIA 3WV1A 1UTZA 3L0VA 4FXQA 2DW0A 5I12A 2CKIA 3KECA 3GBOA 4JPAA 2X3AA 2KRJA 3LUMA 2USNA 4XBHA 3WV3A 2X7MA 5B5OA 1R1JA 1HV5A 5BPAA 1GO7P 2N8RA 4XM8A 1R54A 2K9CA 2D1OA 4L19A 1YCMA 1A86A 3KEKA 3EDZA 4DV8A 2L0RA 1XFVA 2W0DA 1BSWA 3TS4A 4GUYA 3LJZA 4IN9A 1EUBA 3U1RA 1SLMA 1JK3A 1KAPP 1RM8A 4H2EA 4L6TA 3L0TA 4PKTA 1QJJA 1IAAA 1JANA 1Q3AA 1Y93A 1ATLA 2AYKA 4H3XA 2W15A 1J7NA 1JJ9A 1JIWP 2YIGA 5D2BA 3WV2A 1BIWA 1JAOA 2J0TA 4XCTA 2HU6A 1CGEA 1BQQM 2YUFA 4GWMA 1ZXVA 5I43A 4DF9A 2RJPA 1QUAA 3LIKA 2E2DA 1XFXA 1K7QA 1OM7A 3F15A 2JNPA 1KBCA 1OS9A 4DPEA 1KUGA 3G42A 2OVXA 3TT4A 3HYGA 4JP4A 4JIJA 1G49A 2WOAA 3KWVC 1GE5A 1WNIA 3LKAA 4PKSA 2D1NA 4H30A 3USNA 1QJIA 2W12A 3O64A 1BQOA 4Q1LA 1EAKA 5D1UA 3HBVP 2FV9A 1PWUA 3SHIA 3EDHA 2Z2DA 3B2ZA 4H82A 3EWJA 1SMPA 1OMJA 4JQGA 4A7BA 1G4KA 5CZMA 5H8XA 3LQ0A 2DW2A 1UMSA 2RJQA 1XUCA 1ZS0A 3LJTA 4A3WA 5I0LA 3G5CA 3VI1A 3Q2HA 4ON1A 1G9KA 3AIGA 5D3CA 2OW2A 1BKCI 3Q2GA 2XS4A 5D1TA 3EDGA 1C3IA 3DTIA 1CXVA 3DPFA 1PWQA 1I1IP 1R1HA 1KUKA 1XFUA 1BM6A 3CKIA 1JAQA 2I47A 1D8MA 1D5JA 1GXDA 1XUDA 1GE6A 1ROSA 1OM6A 1JIZA 1UEAA 1HFSA 4I35A 1IAEA 4IUWA 4FVLA 4G9LA 2O3EA 3EHYA 2PJTA 1D7XA 1R1IA 4L63A 2X3BA 1YP1A 3DTKA 4PKUA 3K7NA 3KMEA 1XFYA 1B3DA 1PWPA 2MLSA 1CIZA 3N2VA 2MZIA 2OY4A 2OY2A 1ZVXA 2DW1A 3HBUP 4H1QA 3DL1A 1BUVM 4ILWD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BZS A;  2JSD A;  1MMB A;  2DDF A;  1OM8 A;  1O0Q A;  1C7K A;  1EB6 A;  966C A;  4PKV A;  1HOV A;  1OS2 A;  2A8H A;  4IJO A;  1C8T A;  1USN A;  4PKW A;  3KMC A;  3F18 A;  1SLN A;  1B8Y A;  3I7I A;  4GQL A;  5CUH A;  2Y6C A;  1GKC A;  1SAT A;  5B5P A;  1PWV A;  2CLT A;  2E3X A;  3B92 A;  1HY7 A;  1Y0V A;  3TVC A;  3B8Z A;  1CAQ A;  4AYK A;  1GKD A;  1BUD A;  4H76 A;  3LQB A;  1FLS A;  2MLR A;  3DNG A;  3KRY A;  2OVZ A;  4FU4 A;  4J4M A;  1ZXC A;  5I4O A;  5BOT A;  3MA2 A;  4GWN A;  4HMA A;  1I73 A;  3OHL A;  5D1S A;  3BA0 A;  1CGF A;  1A85 A;  4WZV A;  1OO9 A;  2W14 A;  5I3M A;  1XFW A;  3TSK A;  3NX7 A;  2POJ A;  1YOU A;  1YQY A;  1PWW A;  4PKR A;  1K7G A;  1AF0 A;  3LEA A;  3OHO A;  4FXY P;  1ZP5 A;  4EFS A;  3HDB A;  1O0T A;  1XUR A;  3F1A A;  3AYU A;  2AIG P;  3EHX A;  2OZR A;  1IAC A;  3LE9 A;  2O36 A;  4WF6 A;  2TCL A;  2X3C A;  3ZUK A;  1DTH A;  2OXU A;  3EDI A;  1BKC E;  1CGL A;  3E8R A;  3I7G A;  1D8F A;  3RTT A;  3P24 A;  5I2Z A;  3AYK A;  2YB9 A;  3LUN A;  1IAG A;  1S4B P;  2ERO A;  4WKI A;  2W13 A;  4JA1 A;  3DWB A;  3VTG A;  3LIR A;  3LJG A;  1UTT A;  1ZTQ A;  1K7I A;  1MMQ A;  1AYK A;  2OXW A;  4AUO A;  1L6J A;  1AKL A;  2OW0 A;  4QKZ A;  1UMT A;  3V96 B;  4GR8 A;  2OW9 A;  4WKE A;  4XM6 A;  1JH1 A;  1I76 A;  1SRP A;  1SU3 A;  2FV5 A;  2JT6 A;  4GR3 A;  2ERP A;  5CXA A;  1Y8J A;  5LAB A;  2MZH A;  3ZXH A;  1RMZ A;  1GO8 P;  1AST A;  1QIC A;  1ND1 A;  2WO9 A;  1IAB A;  2JIH A;  2OXZ A;  2Y6D A;  5L7F A;  2J83 A;  4CTH A;  3HDA P;  4PKQ A;  4XM7 A;  2OW1 A;  2DDY A;  4H84 A;  4ZR5 A;  3P1V A;  1FBL A;  3HB2 P;  3LK8 A;  2K2G A;  5D7W A;  3F19 A;  4G0D A;  2JT5 A;  3KEJ A;  4DD8 A;  1QIB A;  2XS3 A;  1IAD A;  1G05 A;  3HY7 A;  3O2X A;  4WK7 A;  1G12 A;  5BOY A;  1KUF A;  830C A;  3K7L A;  3LIL A;  456C A;  1Z3J A;  1BKC A;  2V4B A;  3ZVS A;  4GF1 A;  3ELM A;  1MMR A;  5JMY A;  3DPE A;  3F16 A;  1CQR A;  5L79 A;  1R55 A;  4H49 A;  3N2U A;  4AXQ A;  2OI0 A;  1KUI A;  1MMP A;  1JAP A;  4AIG A;  3UVC A;  1GE7 A;  1KUH A;  3LMC A;  2ERQ A;  3DSL A;  1HTD A;  1JKY A;  2SRT A;  4GR0 A;  1HFC A;  4HX3 A;  3HY9 A;  4I03 A;  1XFZ A;  4R3V A;  1DMT A;  3RTS A;  1MNC A;  3LGP A;  1CK7 A;  2QPJ A;  1FM1 A;  3F17 A;  2MZE A;  1H71 P;  1QIA A;  2WO8 A;  3KHI A;  3WV1 A;  1UTZ A;  3L0V A;  4FXQ A;  2DW0 A;  5I12 A;  2CKI A;  3KEC A;  3GBO A;  4JPA A;  2X3A A;  2KRJ A;  3LUM A;  2USN A;  4XBH A;  3WV3 A;  2X7M A;  5B5O A;  1R1J A;  1HV5 A;  5BPA A;  1GO7 P;  2N8R A;  4XM8 A;  1R54 A;  2K9C A;  2D1O A;  4L19 A;  1YCM A;  1A86 A;  3KEK A;  3EDZ A;  4DV8 A;  2L0R A;  1XFV A;  2W0D A;  1BSW A;  3TS4 A;  4GUY A;  3LJZ A;  4IN9 A;  1EUB A;  3U1R A;  1SLM A;  1JK3 A;  1KAP P;  1RM8 A;  4H2E A;  4L6T A;  3L0T A;  4PKT A;  1QJJ A;  1IAA A;  1JAN A;  1Q3A A;  1Y93 A;  1ATL A;  2AYK A;  4H3X A;  2W15 A;  1J7N A;  1JJ9 A;  1JIW P;  2YIG A;  5D2B A;  3WV2 A;  1BIW A;  1JAO A;  2J0T A;  4XCT A;  2HU6 A;  1CGE A;  1BQQ M;  4GWM A;  1ZXV A;  5I43 A;  4DF9 A;  2RJP A;  1QUA A;  3LIK A;  2E2D A;  1XFX A;  1K7Q A;  1OM7 A;  3F15 A;  2JNP A;  1KBC A;  1OS9 A;  4DPE A;  1KUG A;  3G42 A;  2OVX A;  3TT4 A;  3HYG A;  4JP4 A;  4JIJ A;  1G49 A;  2WOA A;  3KWV C;  1GE5 A;  1WNI A;  3LKA A;  4PKS A;  2D1N A;  4H30 A;  3USN A;  1QJI A;  2W12 A;  3O64 A;  1BQO A;  4Q1L A;  1EAK A;  5D1U A;  3HBV P;  2FV9 A;  1PWU A;  3SHI A;  3EDH A;  2Z2D A;  3B2Z A;  4H82 A;  3EWJ A;  1SMP A;  1OMJ A;  4JQG A;  4A7B A;  1G4K A;  5CZM A;  5H8X A;  3LQ0 A;  2DW2 A;  1UMS A;  2RJQ A;  1XUC A;  1ZS0 A;  3LJT A;  4A3W A;  5I0L A;  3G5C A;  3VI1 A;  3Q2H A;  4ON1 A;  1G9K A;  3AIG A;  5D3C A;  2OW2 A;  1BKC I;  3Q2G A;  2XS4 A;  5D1T A;  3EDG A;  1C3I A;  1CXV A;  3DPF A;  1PWQ A;  1I1I P;  1R1H A;  1KUK A;  1XFU A;  1BM6 A;  3CKI A;  1JAQ A;  2I47 A;  1D8M A;  1D5J A;  1GXD A;  1XUD A;  1GE6 A;  1ROS A;  1OM6 A;  1JIZ A;  1UEA A;  1HFS A;  4I35 A;  1IAE A;  4IUW A;  4FVL A;  4G9L A;  2O3E A;  3EHY A;  2PJT A;  1D7X A;  1R1I A;  4L63 A;  2X3B A;  1YP1 A;  4PKU A;  3K7N A;  3KME A;  1XFY A;  1B3D A;  1PWP A;  2MLS A;  1CIZ A;  3N2V A;  2MZI A;  2OY4 A;  2OY2 A;  1ZVX A;  2DW1 A;  3HBU P;  4H1Q A;  3DL1 A;  1BUV M;  4ILW D; 
#chains in the Genus database with same CATH topology
 1BZS A;  2JSD A;  1MMB A;  2DDF A;  1OM8 A;  1O0Q A;  1C7K A;  1EB6 A;  966C A;  4PKV A;  1HOV A;  1OS2 A;  2A8H A;  4IJO A;  1C8T A;  1USN A;  4PKW A;  3KMC A;  3F18 A;  1SLN A;  1B8Y A;  3I7I A;  4GQL A;  5CUH A;  2Y6C A;  1GKC A;  1SAT A;  5B5P A;  1PWV A;  2CLT A;  2E3X A;  3B92 A;  1HY7 A;  1Y0V A;  3TVC A;  3B8Z A;  1CAQ A;  4AYK A;  1GKD A;  1BUD A;  4H76 A;  3LQB A;  1FLS A;  2MLR A;  3DNG A;  3KRY A;  2OVZ A;  4FU4 A;  4J4M A;  1ZXC A;  5I4O A;  5BOT A;  3MA2 A;  4GWN A;  4HMA A;  1I73 A;  3OHL A;  5D1S A;  3BA0 A;  1CGF A;  1A85 A;  4WZV A;  1OO9 A;  2W14 A;  5I3M A;  1XFW A;  3TSK A;  3NX7 A;  2POJ A;  1YOU A;  1YQY A;  1PWW A;  4PKR A;  1K7G A;  1AF0 A;  3LEA A;  3OHO A;  4FXY P;  1ZP5 A;  4EFS A;  3HDB A;  1O0T A;  1XUR A;  3F1A A;  3AYU A;  2AIG P;  3EHX A;  2OZR A;  1IAC A;  3LE9 A;  2O36 A;  4WF6 A;  2TCL A;  2X3C A;  3ZUK A;  1DTH A;  2OXU A;  3EDI A;  1BKC E;  1CGL A;  3E8R A;  3I7G A;  1D8F A;  3RTT A;  3P24 A;  5I2Z A;  3AYK A;  2YB9 A;  3LUN A;  1IAG A;  1S4B P;  2ERO A;  4WKI A;  2W13 A;  4JA1 A;  3DWB A;  3VTG A;  3LIR A;  3LJG A;  1UTT A;  1ZTQ A;  1K7I A;  1MMQ A;  1AYK A;  2OXW A;  4AUO A;  1L6J A;  1AKL A;  2OW0 A;  4QKZ A;  1UMT A;  3V96 B;  4GR8 A;  2OW9 A;  4WKE A;  4XM6 A;  1JH1 A;  1I76 A;  1SRP A;  1SU3 A;  2FV5 A;  2JT6 A;  4GR3 A;  2ERP A;  5CXA A;  1Y8J A;  5LAB A;  2MZH A;  3ZXH A;  1RMZ A;  1GO8 P;  3DTE A;  1AST A;  1QIC A;  1ND1 A;  2WO9 A;  1IAB A;  2JIH A;  2OXZ A;  2Y6D A;  5L7F A;  2J83 A;  4CTH A;  3HDA P;  4PKQ A;  4XM7 A;  2OW1 A;  2DDY A;  4H84 A;  4ZR5 A;  3P1V A;  1FBL A;  3HB2 P;  3LK8 A;  2K2G A;  5D7W A;  3F19 A;  4G0D A;  2JT5 A;  3KEJ A;  4DD8 A;  1QIB A;  2XS3 A;  1IAD A;  1G05 A;  3HY7 A;  3O2X A;  4WK7 A;  1G12 A;  5BOY A;  1KUF A;  830C A;  3K7L A;  3LIL A;  456C A;  1TVI A;  1Z3J A;  1BKC A;  2V4B A;  3ZVS A;  4GF1 A;  3ELM A;  1MMR A;  5JMY A;  3DPE A;  3F16 A;  1CQR A;  5L79 A;  1R55 A;  4H49 A;  3N2U A;  4AXQ A;  2OI0 A;  1KUI A;  1MMP A;  1JAP A;  4AIG A;  3UVC A;  1GE7 A;  1KUH A;  3DSL A;  2ERQ A;  3LMC A;  1HTD A;  1JKY A;  2SRT A;  4GR0 A;  1HFC A;  4HX3 A;  3HY9 A;  4I03 A;  1XFZ A;  4R3V A;  1DMT A;  3RTS A;  4L7A A;  1MNC A;  3LGP A;  1CK7 A;  2QPJ A;  1FM1 A;  3F17 A;  2MZE A;  1H71 P;  1QIA A;  2WO8 A;  3KHI A;  3WV1 A;  1UTZ A;  3L0V A;  4FXQ A;  2DW0 A;  5I12 A;  2CKI A;  3KEC A;  3GBO A;  4JPA A;  2X3A A;  2KRJ A;  3LUM A;  2USN A;  4XBH A;  3WV3 A;  2X7M A;  5B5O A;  1R1J A;  1HV5 A;  5BPA A;  1GO7 P;  2N8R A;  4XM8 A;  1R54 A;  2K9C A;  2D1O A;  4L19 A;  1YCM A;  1A86 A;  3KEK A;  3EDZ A;  4DV8 A;  2L0R A;  1XFV A;  2W0D A;  1BSW A;  3TS4 A;  4GUY A;  3LJZ A;  4IN9 A;  1EUB A;  3U1R A;  1SLM A;  1JK3 A;  1KAP P;  1RM8 A;  4H2E A;  4L6T A;  3L0T A;  4PKT A;  1QJJ A;  1IAA A;  1JAN A;  1Q3A A;  1Y93 A;  1ATL A;  2AYK A;  4H3X A;  2W15 A;  1J7N A;  1JJ9 A;  1JIW P;  2YIG A;  5D2B A;  3WV2 A;  1BIW A;  1JAO A;  2J0T A;  4XCT A;  2HU6 A;  1CGE A;  1BQQ M;  2YUF A;  4GWM A;  1ZXV A;  5I43 A;  4DF9 A;  2RJP A;  1QUA A;  3LIK A;  2E2D A;  1XFX A;  1K7Q A;  1OM7 A;  3F15 A;  2JNP A;  1KBC A;  1OS9 A;  4DPE A;  1KUG A;  3G42 A;  2OVX A;  3TT4 A;  3HYG A;  4JP4 A;  4JIJ A;  1G49 A;  2WOA A;  3KWV C;  1GE5 A;  1WNI A;  3LKA A;  4PKS A;  2D1N A;  4H30 A;  3USN A;  1QJI A;  2W12 A;  3O64 A;  1BQO A;  4Q1L A;  1EAK A;  5D1U A;  3HBV P;  2FV9 A;  1PWU A;  3SHI A;  1XAX A;  3EDH A;  2Z2D A;  3B2Z A;  4H82 A;  3EWJ A;  1SMP A;  1OMJ A;  4JQG A;  4A7B A;  1G4K A;  5CZM A;  5H8X A;  3LQ0 A;  2DW2 A;  1UMS A;  2RJQ A;  1XUC A;  1ZS0 A;  3LJT A;  4A3W A;  5I0L A;  3G5C A;  3VI1 A;  3Q2H A;  4ON1 A;  1G9K A;  3AIG A;  5D3C A;  2OW2 A;  1BKC I;  3Q2G A;  1OZ9 A;  2XS4 A;  5D1T A;  3EDG A;  1C3I A;  3DTI A;  1CXV A;  3DPF A;  1PWQ A;  1I1I P;  1R1H A;  1KUK A;  1XFU A;  1BM6 A;  3CKI A;  1JAQ A;  2I47 A;  1D8M A;  1D5J A;  1GXD A;  1XUD A;  1GE6 A;  1ROS A;  1OM6 A;  1JIZ A;  1UEA A;  1HFS A;  4I35 A;  1IAE A;  4IUW A;  4FVL A;  4G9L A;  2O3E A;  3EHY A;  2PJT A;  1D7X A;  1R1I A;  4L63 A;  2X3B A;  1YP1 A;  3DTK A;  4PKU A;  3K7N A;  3KME A;  1XFY A;  1B3D A;  1PWP A;  2MLS A;  1CIZ A;  3N2V A;  2MZI A;  2OY4 A;  2OY2 A;  1ZVX A;  2DW1 A;  3HBU P;  4H1Q A;  1XM5 A;  3DL1 A;  1BUV M;  4ILW D; 
#chains in the Genus database with same CATH homology
 1BZS A;  2JSD A;  1MMB A;  2DDF A;  1OM8 A;  1O0Q A;  1C7K A;  1EB6 A;  966C A;  4PKV A;  1HOV A;  1OS2 A;  2A8H A;  4IJO A;  1C8T A;  1USN A;  4PKW A;  3KMC A;  3F18 A;  1SLN A;  1B8Y A;  3I7I A;  4GQL A;  5CUH A;  2Y6C A;  1GKC A;  1SAT A;  5B5P A;  1PWV A;  2CLT A;  2E3X A;  3B92 A;  1HY7 A;  1Y0V A;  3TVC A;  3B8Z A;  1CAQ A;  4AYK A;  1GKD A;  1BUD A;  4H76 A;  3LQB A;  1FLS A;  2MLR A;  3DNG A;  3KRY A;  2OVZ A;  4FU4 A;  4J4M A;  1ZXC A;  5I4O A;  5BOT A;  3MA2 A;  4GWN A;  4HMA A;  1I73 A;  3OHL A;  5D1S A;  3BA0 A;  1CGF A;  1A85 A;  4WZV A;  1OO9 A;  2W14 A;  5I3M A;  1XFW A;  3TSK A;  3NX7 A;  2POJ A;  1YOU A;  1YQY A;  1PWW A;  4PKR A;  1K7G A;  1AF0 A;  3LEA A;  3OHO A;  4FXY P;  1ZP5 A;  4EFS A;  3HDB A;  1O0T A;  1XUR A;  3F1A A;  3AYU A;  2AIG P;  3EHX A;  2OZR A;  1IAC A;  3LE9 A;  2O36 A;  4WF6 A;  2TCL A;  2X3C A;  3ZUK A;  1DTH A;  2OXU A;  3EDI A;  1BKC E;  1CGL A;  3E8R A;  3I7G A;  1D8F A;  3RTT A;  3P24 A;  5I2Z A;  3AYK A;  2YB9 A;  3LUN A;  1IAG A;  1S4B P;  2ERO A;  4WKI A;  2W13 A;  4JA1 A;  3DWB A;  3VTG A;  3LIR A;  3LJG A;  1UTT A;  1ZTQ A;  1K7I A;  1MMQ A;  1AYK A;  2OXW A;  4AUO A;  1L6J A;  1AKL A;  2OW0 A;  4QKZ A;  1UMT A;  3V96 B;  4GR8 A;  2OW9 A;  4WKE A;  4XM6 A;  1JH1 A;  1I76 A;  1SRP A;  1SU3 A;  2FV5 A;  2JT6 A;  4GR3 A;  2ERP A;  5CXA A;  1Y8J A;  5LAB A;  2MZH A;  3ZXH A;  1RMZ A;  1GO8 P;  3DTE A;  1AST A;  1QIC A;  1ND1 A;  2WO9 A;  1IAB A;  2JIH A;  2OXZ A;  2Y6D A;  5L7F A;  2J83 A;  4CTH A;  3HDA P;  4PKQ A;  4XM7 A;  2OW1 A;  2DDY A;  4H84 A;  4ZR5 A;  3P1V A;  1FBL A;  3HB2 P;  3LK8 A;  2K2G A;  5D7W A;  3F19 A;  4G0D A;  2JT5 A;  3KEJ A;  4DD8 A;  1QIB A;  2XS3 A;  1IAD A;  1G05 A;  3HY7 A;  3O2X A;  4WK7 A;  1G12 A;  5BOY A;  1KUF A;  830C A;  3K7L A;  3LIL A;  456C A;  1Z3J A;  1BKC A;  2V4B A;  3ZVS A;  4GF1 A;  3ELM A;  1MMR A;  5JMY A;  3DPE A;  3F16 A;  1CQR A;  5L79 A;  1R55 A;  4H49 A;  3N2U A;  4AXQ A;  2OI0 A;  1KUI A;  1MMP A;  1JAP A;  4AIG A;  3UVC A;  1GE7 A;  1KUH A;  3DSL A;  2ERQ A;  3LMC A;  1HTD A;  1JKY A;  2SRT A;  4GR0 A;  1HFC A;  4HX3 A;  3HY9 A;  4I03 A;  1XFZ A;  4R3V A;  1DMT A;  3RTS A;  4L7A A;  1MNC A;  3LGP A;  1CK7 A;  2QPJ A;  1FM1 A;  3F17 A;  2MZE A;  1H71 P;  1QIA A;  2WO8 A;  3KHI A;  3WV1 A;  1UTZ A;  3L0V A;  4FXQ A;  2DW0 A;  5I12 A;  2CKI A;  3KEC A;  3GBO A;  4JPA A;  2X3A A;  2KRJ A;  3LUM A;  2USN A;  4XBH A;  3WV3 A;  2X7M A;  5B5O A;  1R1J A;  1HV5 A;  5BPA A;  1GO7 P;  2N8R A;  4XM8 A;  1R54 A;  2K9C A;  2D1O A;  4L19 A;  1YCM A;  1A86 A;  3KEK A;  3EDZ A;  4DV8 A;  2L0R A;  1XFV A;  2W0D A;  1BSW A;  3TS4 A;  4GUY A;  3LJZ A;  4IN9 A;  1EUB A;  3U1R A;  1SLM A;  1JK3 A;  1KAP P;  1RM8 A;  4H2E A;  4L6T A;  3L0T A;  4PKT A;  1QJJ A;  1IAA A;  1JAN A;  1Q3A A;  1Y93 A;  1ATL A;  2AYK A;  4H3X A;  2W15 A;  1J7N A;  1JJ9 A;  1JIW P;  2YIG A;  5D2B A;  3WV2 A;  1BIW A;  1JAO A;  2J0T A;  4XCT A;  2HU6 A;  1CGE A;  1BQQ M;  2YUF A;  4GWM A;  1ZXV A;  5I43 A;  4DF9 A;  2RJP A;  1QUA A;  3LIK A;  2E2D A;  1XFX A;  1K7Q A;  1OM7 A;  3F15 A;  2JNP A;  1KBC A;  1OS9 A;  4DPE A;  1KUG A;  3G42 A;  2OVX A;  3TT4 A;  3HYG A;  4JP4 A;  4JIJ A;  1G49 A;  2WOA A;  3KWV C;  1GE5 A;  1WNI A;  3LKA A;  4PKS A;  2D1N A;  4H30 A;  3USN A;  1QJI A;  2W12 A;  3O64 A;  1BQO A;  4Q1L A;  1EAK A;  5D1U A;  3HBV P;  2FV9 A;  1PWU A;  3SHI A;  3EDH A;  2Z2D A;  3B2Z A;  4H82 A;  3EWJ A;  1SMP A;  1OMJ A;  4JQG A;  4A7B A;  1G4K A;  5CZM A;  5H8X A;  3LQ0 A;  2DW2 A;  1UMS A;  2RJQ A;  1XUC A;  1ZS0 A;  3LJT A;  4A3W A;  5I0L A;  3G5C A;  3VI1 A;  3Q2H A;  4ON1 A;  1G9K A;  3AIG A;  5D3C A;  2OW2 A;  1BKC I;  3Q2G A;  2XS4 A;  5D1T A;  3EDG A;  1C3I A;  3DTI A;  1CXV A;  3DPF A;  1PWQ A;  1I1I P;  1R1H A;  1KUK A;  1XFU A;  1BM6 A;  3CKI A;  1JAQ A;  2I47 A;  1D8M A;  1D5J A;  1GXD A;  1XUD A;  1GE6 A;  1ROS A;  1OM6 A;  1JIZ A;  1UEA A;  1HFS A;  4I35 A;  1IAE A;  4IUW A;  4FVL A;  4G9L A;  2O3E A;  3EHY A;  2PJT A;  1D7X A;  1R1I A;  4L63 A;  2X3B A;  1YP1 A;  3DTK A;  4PKU A;  3K7N A;  3KME A;  1XFY A;  1B3D A;  1PWP A;  2MLS A;  1CIZ A;  3N2V A;  2MZI A;  2OY4 A;  2OY2 A;  1ZVX A;  2DW1 A;  3HBU P;  4H1Q A;  3DL1 A;  1BUV M;  4ILW D; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...