4ZR5A

Soluble rabbit neprilysin in complex with phosphoramidon
Total Genus 278
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
278
sequence length
696
structure length
696
Chain Sequence
GICKSSDCIKSAARLIQNMDATAEPCTDFFKYACGGWLKRNVIPETSSRYSNFDILRDELEVILKDVLQEPKTEDIVAVQKAKTLYRSCVNETAIDSRGGQPLLKLLPDVYGWPVATQNWEQTYGTSWSAEKSIAQLNSKYGKKVLINFFVGTDDKNSMNHIIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMIAVAKLIRQEEGLPIDENQISVEMNKVMELEKEIANATTKSEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWSNFTNEIMSTVNINIPNEEDVVVYAPEYLIKLKPILTKYSPRDLQNLMSWRFIMDLVSSLSRTYKDSRNAFRKALYGTTSESATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKKAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWITGAAIVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSANNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGIGQAYRAYQNYVKKNGEEKLLPGIDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGSLQNSVEFSEAFQCPKNSYMNPEKKCRVW
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structures of Soluble Rabbit Neutral Endopeptidase (Neprilysin) Complexed with Phosphoramidon and Thiorphan
rcsb
molecule tags Hydrolase
source organism Oryctolagus cuniculus
molecule keywords Neprilysin
total genus 278
structure length 696
sequence length 696
chains with identical sequence B
ec nomenclature ec 3.4.24.11: Neprilysin.
pdb deposition date 2015-05-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01431 Peptidase_M13 Peptidase family M13
A PF05649 Peptidase_M13_N Peptidase family M13
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1380.10 Mainly Alpha Orthogonal Bundle Neutral endopeptidase; domain 2 Neutral endopeptidase , domain2 4zr5A02
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 4zr5A01
3KECA 1CGLA 1CK7A 2OVXA 1JIZA 1BSWA 5I3MA 1Y93A 5D2BA 5BPAA 4FU4A 2EROA 4I35A 2FV9A 3V96B 1I76A 2OY2A 1XUDA 1AKLA 2W15A 3ZXHA 1C8TA 3B2ZA 1CGEA 1BKCA 4H30A 1BQOA 2MLRA 1UTTA 2W13A 3N2UA 4XM8A 3EWJA 3EHXA 2MLSA 2ERPA 1BKCE 2WO8A 2OW9A 3LGPA 4WKEA 3DPEA 3HBVP 5JMYA 2X3CA 1UTZA 3OHLA 4GUYA 3HYGA 4AYKA 3LIRA 1IADA 2XS4A 1PWUA 1O0TA 1FM1A 1QICA 2K2GA 3KHIA 1XFWA 1CIZA 3LQBA 2MZEA 2E3XA 3DL1A 2ERQA 1KUIA 1R54A 2OXWA 3Q2HA 1R1IA 1FLSA 1GKCA 1B3DA 1ZXCA 4DF9A 1OO9A 966CA 1CGFA 1YOUA 1OS2A 1OM8A 1BUVM 2Y6DA 1SATA 456CA 2DW1A 1BQQM 1HY7A 1XURA 1PWVA 2HU6A 1YCMA 5CZMA 5I0LA 3ZVSA 1KAPP 2YIGA 1IAGA 2KRJA 1K7IA 1QIBA 1G9KA 1ZVXA 1HV5A 2MZIA 3WV3A 1A86A 1GE6A 4IUWA 3HDBA 3EDZA 1G05A 5CXAA 1KBCA 1HTDA 3HY7A 3F16A 1OMJA 1PWWA 1JANA 1C3IA 4WK7A 2L0RA 5D3CA 1MMBA 3LJTA 1SMPA 2W12A 1JAQA 1PWQA 3LJZA 3UVCA 3EDIA 4J4MA 4AUOA 2OXZA 1UEAA 2V4BA 3P24A 1KUKA 3DSLA 2WOAA 1UMTA 3F15A 3BA0A 3LJGA 2D1OA 3LILA 2CKIA 2X3AA 1IAEA 3K7LA 3O64A 4XCTA 1OM6A 1BKCI 5I12A 3O2XA 1S4BP 830CA 4JIJA 2JNPA 2POJA 3ELMA 3L0VA 3N2VA 2K9CA 4GF1A 1FBLA 1SLNA 3TVCA 4DPEA 2USNA 3EHYA 2W0DA 1CAQA 3KMCA 1ND1A 1GE5A 3F1AA 1G49A 1D8FA 2RJQA 3I7GA 1OM7A 4PKVA 4L63A 4WF6A 3VTGA 1UMSA 1DMTA 3B92A 5I2ZA 1QJIA 1QUAA 3GBOA 1OS9A 1AYKA 1HFSA 3KEKA 1XFYA 4QKZA 5BOYA 4PKQA 1ATLA 3DNGA 1B8YA 1ZXVA 4L6TA 5H8XA 5B5PA 3LQ0A 1SRPA 3AIGA 3CKIA 1R1HA 1ROSA 2JT5A 3L0TA 1XFUA 3MA2A 4H76A 4ZR5A 5D1TA 3LUNA 1MMPA 1MNCA 1EAKA 2A8HA 3HY9A 1Y8JA 1EUBA 4Q1LA 4HMAA 1R1JA 3RTTA 4DD8A 4H3XA 1AF0A 2JT6A 1KUGA 3I7IA 1SU3A 3TS4A 5BOTA 2AIGP 1C7KA 1ZTQA 2OW0A 2N8RA 1YP1A 3EDHA 4GWMA 1GO7P 2DW2A 1BM6A 4WKIA 1USNA 1HOVA 1Y0VA 4EFSA 3KEJA 3F17A 1JK3A 5D7WA 1IABA 1H71P 4FVLA 4GR3A 2I47A 2OY4A 1CXVA 1RMZA 2Y6CA 1L6JA 4IN9A 4A7BA 1BIWA 5I4OA 1D7XA 3G42A 4H2EA 1JIWP 4FXYP 4HX3A 1IACA 1XFZA 2OW2A 3LMCA 4H82A 3RTSA 3U1RA 3F18A 4AXQA 1MMQA 2D1NA 5D1UA 4PKUA 1R55A 3LK8A 5CUHA 2CLTA 1ZS0A 2DDYA 1XFVA 3EDGA 5B5OA 4ILWD 2RJPA 2DW0A 4FXQA 3HBUP 3LKAA 4WZVA 4JA1A 2JSDA 2DDFA 1JAOA 1I1IP 2MZHA 3K7NA 3NX7A 5LABA 1J7NA 2O36A 4XM7A 4GR0A 2OXUA 3USNA 3DWBA 2J0TA 4GWNA 2AYKA 2OVZA 1RM8A 2JIHA 1CQRA 1I73A 5L7FA 2FV5A 1D8MA 3ZUKA 4GR8A 2E2DA 2WO9A 2X3BA 3LEAA 1JKYA 1MMRA 2QPJA 1EB6A 5D1SA 2J83A 3B8ZA 3AYKA 4GQLA 4PKTA 2O3EA 3KRYA 3TSKA 3TT4A 4JQGA 3AYUA 3OHOA 1BUDA 2SRTA 4ON1A 1XUCA 1BZSA 4AIGA 1Q3AA 3HDAP 3KWVC 3LIKA 1QIAA 3LE9A 1K7QA 3Q2GA 4XBHA 2YB9A 1IAAA 4XM6A 2X7MA 2W14A 4PKSA 1GXDA 2OI0A 2PJTA 3WV1A 1GE7A 3F19A 1G12A 1HFCA 4A3WA 1QJJA 3E8RA 2XS3A 4JP4A 4G0DA 1KUHA 1A85A 1JJ9A 4PKRA 4H49A 3WV2A 1ZP5A 5I43A 1DTHA 1GO8P 1D5JA 1YQYA 3KMEA 3LUMA 1JH1A 1Z3JA 4JPAA 1SLMA 3HB2P 1K7GA 3G5CA 4CTHA 4I03A 2TCLA 3P1VA 1O0QA 2OW1A 1ASTA 1KUFA 4H1QA 1WNIA 1GKDA 3VI1A 4H84A 4PKWA 1JAPA 2Z2DA 4R3VA 1XFXA 4G9LA 1PWPA 4L19A 1G4KA 3DPFA 3SHIA 4DV8A 4IJOA 2OZRA 5L79A
chains in the Genus database with same CATH superfamily
3KECA 1CGLA 1CK7A 2OVXA 1JIZA 1BSWA 5I3MA 1Y93A 5D2BA 5BPAA 4FU4A 2EROA 4I35A 2FV9A 3V96B 1I76A 2OY2A 1XUDA 1AKLA 2W15A 3ZXHA 1C8TA 3B2ZA 1CGEA 1BKCA 4H30A 1BQOA 2MLRA 1UTTA 2W13A 3N2UA 4XM8A 3EWJA 3EHXA 2MLSA 2ERPA 1BKCE 2WO8A 2OW9A 3LGPA 4WKEA 3DPEA 3HBVP 5JMYA 2X3CA 1UTZA 3OHLA 4GUYA 3HYGA 4AYKA 3LIRA 1IADA 2XS4A 1PWUA 1O0TA 1XAXA 1FM1A 1QICA 2K2GA 3KHIA 1XFWA 1CIZA 3LQBA 2MZEA 2E3XA 3DL1A 2ERQA 1KUIA 1R54A 2OXWA 3Q2HA 1R1IA 1XM5A 1FLSA 1GKCA 1B3DA 1ZXCA 4DF9A 1OO9A 966CA 1CGFA 1YOUA 1OS2A 1OM8A 1BUVM 2Y6DA 1SATA 456CA 2DW1A 1BQQM 1HY7A 1XURA 1PWVA 2HU6A 1YCMA 5CZMA 5I0LA 3ZVSA 1KAPP 2YIGA 1IAGA 2KRJA 1K7IA 1QIBA 1G9KA 1ZVXA 1HV5A 2MZIA 3WV3A 1A86A 1GE6A 4IUWA 3HDBA 3EDZA 1G05A 5CXAA 1KBCA 1HTDA 3HY7A 3F16A 1OMJA 1PWWA 1JANA 1C3IA 4WK7A 2L0RA 5D3CA 1MMBA 3LJTA 1SMPA 2W12A 1JAQA 1PWQA 3LJZA 3UVCA 3EDIA 4J4MA 4AUOA 2OXZA 1UEAA 2V4BA 3P24A 1KUKA 3DSLA 2WOAA 1UMTA 3F15A 3BA0A 3LJGA 2D1OA 3LILA 2CKIA 2X3AA 1IAEA 3K7LA 3O64A 4XCTA 1OM6A 1BKCI 5I12A 3O2XA 1S4BP 3DTKA 830CA 4JIJA 2JNPA 2POJA 3ELMA 3L0VA 2YUFA 3N2VA 2K9CA 4GF1A 1FBLA 1OZ9A 1SLNA 3TVCA 4DPEA 2USNA 3EHYA 2W0DA 1CAQA 3KMCA 1ND1A 1GE5A 3F1AA 1G49A 1D8FA 2RJQA 3I7GA 1OM7A 1TVIA 4PKVA 4L63A 4WF6A 3VTGA 1UMSA 1DMTA 3B92A 5I2ZA 1QJIA 1QUAA 3GBOA 1OS9A 1AYKA 1HFSA 3KEKA 1XFYA 4QKZA 5BOYA 4PKQA 1ATLA 3DNGA 1B8YA 1ZXVA 4L6TA 5H8XA 5B5PA 3LQ0A 1SRPA 3AIGA 3CKIA 1R1HA 1ROSA 2JT5A 3L0TA 1XFUA 3MA2A 4H76A 4ZR5A 5D1TA 3LUNA 1MMPA 1MNCA 1EAKA 2A8HA 3HY9A 1Y8JA 1EUBA 4Q1LA 4HMAA 1R1JA 3RTTA 4DD8A 4H3XA 1AF0A 2JT6A 1KUGA 3I7IA 1SU3A 3TS4A 5BOTA 2AIGP 1C7KA 1ZTQA 2OW0A 2N8RA 1YP1A 3EDHA 4GWMA 1GO7P 2DW2A 1BM6A 4WKIA 1USNA 1HOVA 1Y0VA 4EFSA 3KEJA 3F17A 1JK3A 5D7WA 1IABA 1H71P 4FVLA 4GR3A 2I47A 2OY4A 1CXVA 1RMZA 2Y6CA 1L6JA 4IN9A 4A7BA 1BIWA 5I4OA 1D7XA 3G42A 4H2EA 1JIWP 4FXYP 4HX3A 1IACA 1XFZA 2OW2A 3LMCA 4H82A 3RTSA 3U1RA 3F18A 4AXQA 1MMQA 2D1NA 5D1UA 3DTEA 4PKUA 1R55A 3LK8A 5CUHA 2CLTA 1ZS0A 2DDYA 1XFVA 3EDGA 5B5OA 4ILWD 2RJPA 2DW0A 4FXQA 3HBUP 3LKAA 4WZVA 4JA1A 2JSDA 2DDFA 1JAOA 1I1IP 2MZHA 3K7NA 3NX7A 5LABA 1J7NA 2O36A 4XM7A 4GR0A 2OXUA 3USNA 3DWBA 2J0TA 4GWNA 2AYKA 2OVZA 1RM8A 2JIHA 1CQRA 1I73A 5L7FA 2FV5A 1D8MA 3ZUKA 4GR8A 2E2DA 2WO9A 2X3BA 3LEAA 1JKYA 1MMRA 2QPJA 1EB6A 5D1SA 2J83A 3B8ZA 3AYKA 4GQLA 4PKTA 2O3EA 3KRYA 3TSKA 3TT4A 4JQGA 3AYUA 3OHOA 1BUDA 2SRTA 4ON1A 1XUCA 1BZSA 4AIGA 1Q3AA 3HDAP 3KWVC 3LIKA 1QIAA 3LE9A 1K7QA 3Q2GA 4XBHA 2YB9A 1IAAA 4XM6A 2X7MA 2W14A 4PKSA 1GXDA 2OI0A 2PJTA 4L7AA 3WV1A 1GE7A 3F19A 1G12A 1HFCA 4A3WA 1QJJA 3E8RA 2XS3A 4JP4A 4G0DA 1KUHA 1A85A 1JJ9A 4PKRA 4H49A 3WV2A 1ZP5A 5I43A 1DTHA 1GO8P 1D5JA 1YQYA 3KMEA 3LUMA 1JH1A 1Z3JA 4JPAA 1SLMA 3HB2P 1K7GA 3G5CA 4CTHA 4I03A 2TCLA 3P1VA 1O0QA 2OW1A 1ASTA 1KUFA 4H1QA 1WNIA 1GKDA 3VI1A 4H84A 4PKWA 1JAPA 2Z2DA 4R3VA 1XFXA 4G9LA 1PWPA 4L19A 1G4KA 3DPFA 3DTIA 3SHIA 4DV8A 4IJOA 2OZRA 5L79A
chains in the Genus database with same CATH topology
3KECA 1CGLA 1CK7A 2OVXA 1JIZA 1BSWA 5I3MA 1Y93A 5D2BA 5BPAA 4FU4A 2EROA 4I35A 2FV9A 3V96B 1I76A 2OY2A 1XUDA 1AKLA 2W15A 3ZXHA 1C8TA 3B2ZA 1CGEA 1BKCA 4H30A 1BQOA 2MLRA 1UTTA 2W13A 3N2UA 4XM8A 3EWJA 3EHXA 2MLSA 2ERPA 1BKCE 2WO8A 2OW9A 3LGPA 4WKEA 3DPEA 3HBVP 5JMYA 2X3CA 1UTZA 3OHLA 4GUYA 3HYGA 4AYKA 3LIRA 1IADA 2XS4A 1PWUA 1O0TA 1FM1A 1QICA 2K2GA 3KHIA 1XFWA 1CIZA 3LQBA 2MZEA 2E3XA 3DL1A 2ERQA 1KUIA 1R54A 2OXWA 3Q2HA 1R1IA 1FLSA 1GKCA 1B3DA 1ZXCA 4DF9A 1OO9A 966CA 1CGFA 1YOUA 1OS2A 1OM8A 1BUVM 2Y6DA 1SATA 456CA 2DW1A 1BQQM 1HY7A 1XURA 1PWVA 2HU6A 1YCMA 5CZMA 5I0LA 3ZVSA 1KAPP 2YIGA 1IAGA 2KRJA 1K7IA 1QIBA 1G9KA 1ZVXA 1HV5A 2MZIA 3WV3A 1A86A 1GE6A 4IUWA 3HDBA 3EDZA 1G05A 5CXAA 1KBCA 1HTDA 3HY7A 3F16A 1OMJA 1PWWA 1JANA 1C3IA 4WK7A 2L0RA 5D3CA 1MMBA 3LJTA 1SMPA 2W12A 1JAQA 1PWQA 3LJZA 3UVCA 3EDIA 4J4MA 4AUOA 2OXZA 1UEAA 2V4BA 3P24A 1KUKA 3DSLA 2WOAA 1UMTA 3F15A 3BA0A 3LJGA 2D1OA 3LILA 2CKIA 2X3AA 1IAEA 3K7LA 3O64A 4XCTA 1OM6A 1BKCI 5I12A 3O2XA 1S4BP 3DTKA 830CA 4JIJA 2JNPA 2POJA 3ELMA 3L0VA 2YUFA 3N2VA 2K9CA 4GF1A 1FBLA 1SLNA 3TVCA 4DPEA 2USNA 3EHYA 2W0DA 1CAQA 3KMCA 1ND1A 1GE5A 3F1AA 1G49A 1D8FA 2RJQA 3I7GA 1OM7A 4PKVA 4L63A 4WF6A 3VTGA 1UMSA 1DMTA 3B92A 5I2ZA 1QJIA 1QUAA 3GBOA 1OS9A 1AYKA 1HFSA 3KEKA 1XFYA 4QKZA 5BOYA 4PKQA 1ATLA 3DNGA 1B8YA 1ZXVA 4L6TA 5H8XA 5B5PA 3LQ0A 1SRPA 3AIGA 3CKIA 1R1HA 1ROSA 2JT5A 3L0TA 1XFUA 3MA2A 4H76A 4ZR5A 5D1TA 3LUNA 1MMPA 1MNCA 1EAKA 2A8HA 3HY9A 1Y8JA 1EUBA 4Q1LA 4HMAA 1R1JA 3RTTA 4DD8A 4H3XA 1AF0A 2JT6A 1KUGA 3I7IA 1SU3A 3TS4A 5BOTA 2AIGP 1C7KA 1ZTQA 2OW0A 2N8RA 1YP1A 3EDHA 4GWMA 1GO7P 2DW2A 1BM6A 4WKIA 1USNA 1HOVA 1Y0VA 4EFSA 3KEJA 3F17A 1JK3A 5D7WA 1IABA 1H71P 4FVLA 4GR3A 2I47A 2OY4A 1CXVA 1RMZA 2Y6CA 1L6JA 4IN9A 4A7BA 1BIWA 5I4OA 1D7XA 3G42A 4H2EA 1JIWP 4FXYP 4HX3A 1IACA 1XFZA 2OW2A 3LMCA 4H82A 3RTSA 3U1RA 3F18A 4AXQA 1MMQA 2D1NA 5D1UA 3DTEA 4PKUA 1R55A 3LK8A 5CUHA 2CLTA 1ZS0A 2DDYA 1XFVA 3EDGA 5B5OA 4ILWD 2RJPA 2DW0A 4FXQA 3HBUP 3LKAA 4WZVA 4JA1A 2JSDA 2DDFA 1JAOA 1I1IP 2MZHA 3K7NA 3NX7A 5LABA 1J7NA 2O36A 4XM7A 4GR0A 2OXUA 3USNA 3DWBA 2J0TA 4GWNA 2AYKA 2OVZA 1RM8A 2JIHA 1CQRA 1I73A 5L7FA 2FV5A 1D8MA 3ZUKA 4GR8A 2E2DA 2WO9A 2X3BA 3LEAA 1JKYA 1MMRA 2QPJA 1EB6A 5D1SA 2J83A 3B8ZA 3AYKA 4GQLA 4PKTA 2O3EA 3KRYA 3TSKA 3TT4A 4JQGA 3AYUA 3OHOA 1BUDA 2SRTA 4ON1A 1XUCA 1BZSA 4AIGA 1Q3AA 3HDAP 3KWVC 3LIKA 1QIAA 3LE9A 1K7QA 3Q2GA 4XBHA 2YB9A 1IAAA 4XM6A 2X7MA 2W14A 4PKSA 1GXDA 2OI0A 2PJTA 4L7AA 3WV1A 1GE7A 3F19A 1G12A 1HFCA 4A3WA 1QJJA 3E8RA 2XS3A 4JP4A 4G0DA 1KUHA 1A85A 1JJ9A 4PKRA 4H49A 3WV2A 1ZP5A 5I43A 1DTHA 1GO8P 1D5JA 1YQYA 3KMEA 3LUMA 1JH1A 1Z3JA 4JPAA 1SLMA 3HB2P 1K7GA 3G5CA 4CTHA 4I03A 2TCLA 3P1VA 1O0QA 2OW1A 1ASTA 1KUFA 4H1QA 1WNIA 1GKDA 3VI1A 4H84A 4PKWA 1JAPA 2Z2DA 4R3VA 1XFXA 4G9LA 1PWPA 4L19A 1G4KA 3DPFA 3DTIA 3SHIA 4DV8A 4IJOA 2OZRA 5L79A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KEC A;  1CGL A;  1CK7 A;  2OVX A;  1JIZ A;  1BSW A;  5I3M A;  1Y93 A;  5D2B A;  5BPA A;  4FU4 A;  2ERO A;  4I35 A;  2FV9 A;  3V96 B;  1I76 A;  2OY2 A;  1XUD A;  1AKL A;  2W15 A;  3ZXH A;  1C8T A;  3B2Z A;  1CGE A;  1BKC A;  4H30 A;  1BQO A;  2MLR A;  1UTT A;  2W13 A;  3N2U A;  4XM8 A;  3EWJ A;  3EHX A;  2MLS A;  2ERP A;  1BKC E;  2WO8 A;  2OW9 A;  3LGP A;  4WKE A;  3DPE A;  3HBV P;  5JMY A;  2X3C A;  1UTZ A;  3OHL A;  4GUY A;  3HYG A;  4AYK A;  3LIR A;  1IAD A;  2XS4 A;  1PWU A;  1O0T A;  1FM1 A;  1QIC A;  2K2G A;  3KHI A;  1XFW A;  1CIZ A;  3LQB A;  2MZE A;  2E3X A;  3DL1 A;  2ERQ A;  1KUI A;  1R54 A;  2OXW A;  3Q2H A;  1R1I A;  1FLS A;  1GKC A;  1B3D A;  1ZXC A;  4DF9 A;  1OO9 A;  966C A;  1CGF A;  1YOU A;  1OS2 A;  1OM8 A;  1BUV M;  2Y6D A;  1SAT A;  456C A;  2DW1 A;  1BQQ M;  1HY7 A;  1XUR A;  1PWV A;  2HU6 A;  1YCM A;  5CZM A;  5I0L A;  3ZVS A;  1KAP P;  2YIG A;  1IAG A;  2KRJ A;  1K7I A;  1QIB A;  1G9K A;  1ZVX A;  1HV5 A;  2MZI A;  3WV3 A;  1A86 A;  1GE6 A;  4IUW A;  3HDB A;  3EDZ A;  1G05 A;  5CXA A;  1KBC A;  1HTD A;  3HY7 A;  3F16 A;  1OMJ A;  1PWW A;  1JAN A;  1C3I A;  4WK7 A;  2L0R A;  5D3C A;  1MMB A;  3LJT A;  1SMP A;  2W12 A;  1JAQ A;  1PWQ A;  3LJZ A;  3UVC A;  3EDI A;  4J4M A;  4AUO A;  2OXZ A;  1UEA A;  2V4B A;  3P24 A;  1KUK A;  3DSL A;  2WOA A;  1UMT A;  3F15 A;  3BA0 A;  3LJG A;  2D1O A;  3LIL A;  2CKI A;  2X3A A;  1IAE A;  3K7L A;  3O64 A;  4XCT A;  1OM6 A;  1BKC I;  5I12 A;  3O2X A;  1S4B P;  830C A;  4JIJ A;  2JNP A;  2POJ A;  3ELM A;  3L0V A;  3N2V A;  2K9C A;  4GF1 A;  1FBL A;  1SLN A;  3TVC A;  4DPE A;  2USN A;  3EHY A;  2W0D A;  1CAQ A;  3KMC A;  1ND1 A;  1GE5 A;  3F1A A;  1G49 A;  1D8F A;  2RJQ A;  3I7G A;  1OM7 A;  4PKV A;  4L63 A;  4WF6 A;  3VTG A;  1UMS A;  1DMT A;  3B92 A;  5I2Z A;  1QJI A;  1QUA A;  3GBO A;  1OS9 A;  1AYK A;  1HFS A;  3KEK A;  1XFY A;  4QKZ A;  5BOY A;  4PKQ A;  1ATL A;  3DNG A;  1B8Y A;  1ZXV A;  4L6T A;  5H8X A;  5B5P A;  3LQ0 A;  1SRP A;  3AIG A;  3CKI A;  1R1H A;  1ROS A;  2JT5 A;  3L0T A;  1XFU A;  3MA2 A;  4H76 A;  4ZR5 A;  5D1T A;  3LUN A;  1MMP A;  1MNC A;  1EAK A;  2A8H A;  3HY9 A;  1Y8J A;  1EUB A;  4Q1L A;  4HMA A;  1R1J A;  3RTT A;  4DD8 A;  4H3X A;  1AF0 A;  2JT6 A;  1KUG A;  3I7I A;  1SU3 A;  3TS4 A;  5BOT A;  2AIG P;  1C7K A;  1ZTQ A;  2OW0 A;  2N8R A;  1YP1 A;  3EDH A;  4GWM A;  1GO7 P;  2DW2 A;  1BM6 A;  4WKI A;  1USN A;  1HOV A;  1Y0V A;  4EFS A;  3KEJ A;  3F17 A;  1JK3 A;  5D7W A;  1IAB A;  1H71 P;  4FVL A;  4GR3 A;  2I47 A;  2OY4 A;  1CXV A;  1RMZ A;  2Y6C A;  1L6J A;  4IN9 A;  4A7B A;  1BIW A;  5I4O A;  1D7X A;  3G42 A;  4H2E A;  1JIW P;  4FXY P;  4HX3 A;  1IAC A;  1XFZ A;  2OW2 A;  3LMC A;  4H82 A;  3RTS A;  3U1R A;  3F18 A;  4AXQ A;  1MMQ A;  2D1N A;  5D1U A;  4PKU A;  1R55 A;  3LK8 A;  5CUH A;  2CLT A;  1ZS0 A;  2DDY A;  1XFV A;  3EDG A;  5B5O A;  4ILW D;  2RJP A;  2DW0 A;  4FXQ A;  3HBU P;  3LKA A;  4WZV A;  4JA1 A;  2JSD A;  2DDF A;  1JAO A;  1I1I P;  2MZH A;  3K7N A;  3NX7 A;  5LAB A;  1J7N A;  2O36 A;  4XM7 A;  4GR0 A;  2OXU A;  3USN A;  3DWB A;  2J0T A;  4GWN A;  2AYK A;  2OVZ A;  1RM8 A;  2JIH A;  1CQR A;  1I73 A;  5L7F A;  2FV5 A;  1D8M A;  3ZUK A;  4GR8 A;  2E2D A;  2WO9 A;  2X3B A;  3LEA A;  1JKY A;  1MMR A;  2QPJ A;  1EB6 A;  5D1S A;  2J83 A;  3B8Z A;  3AYK A;  4GQL A;  4PKT A;  2O3E A;  3KRY A;  3TSK A;  3TT4 A;  4JQG A;  3AYU A;  3OHO A;  1BUD A;  2SRT A;  4ON1 A;  1XUC A;  1BZS A;  4AIG A;  1Q3A A;  3HDA P;  3KWV C;  3LIK A;  1QIA A;  3LE9 A;  1K7Q A;  3Q2G A;  4XBH A;  2YB9 A;  1IAA A;  4XM6 A;  2X7M A;  2W14 A;  4PKS A;  1GXD A;  2OI0 A;  2PJT A;  3WV1 A;  1GE7 A;  3F19 A;  1G12 A;  1HFC A;  4A3W A;  1QJJ A;  3E8R A;  2XS3 A;  4JP4 A;  4G0D A;  1KUH A;  1A85 A;  1JJ9 A;  4PKR A;  4H49 A;  3WV2 A;  1ZP5 A;  5I43 A;  1DTH A;  1GO8 P;  1D5J A;  1YQY A;  3KME A;  3LUM A;  1JH1 A;  1Z3J A;  4JPA A;  1SLM A;  3HB2 P;  1K7G A;  3G5C A;  4CTH A;  4I03 A;  2TCL A;  3P1V A;  1O0Q A;  2OW1 A;  1AST A;  1KUF A;  4H1Q A;  1WNI A;  1GKD A;  3VI1 A;  4H84 A;  4PKW A;  1JAP A;  2Z2D A;  4R3V A;  1XFX A;  4G9L A;  1PWP A;  4L19 A;  1G4K A;  3DPF A;  3SHI A;  4DV8 A;  4IJO A;  2OZR A;  5L79 A; 
#chains in the Genus database with same CATH topology
 3KEC A;  1CGL A;  1CK7 A;  2OVX A;  1JIZ A;  1BSW A;  5I3M A;  1Y93 A;  5D2B A;  5BPA A;  4FU4 A;  2ERO A;  4I35 A;  2FV9 A;  3V96 B;  1I76 A;  2OY2 A;  1XUD A;  1AKL A;  2W15 A;  3ZXH A;  1C8T A;  3B2Z A;  1CGE A;  1BKC A;  4H30 A;  1BQO A;  2MLR A;  1UTT A;  2W13 A;  3N2U A;  4XM8 A;  3EWJ A;  3EHX A;  2MLS A;  2ERP A;  1BKC E;  2WO8 A;  2OW9 A;  3LGP A;  4WKE A;  3DPE A;  3HBV P;  5JMY A;  2X3C A;  1UTZ A;  3OHL A;  4GUY A;  3HYG A;  4AYK A;  3LIR A;  1IAD A;  2XS4 A;  1PWU A;  1O0T A;  1XAX A;  1FM1 A;  1QIC A;  2K2G A;  3KHI A;  1XFW A;  1CIZ A;  3LQB A;  2MZE A;  2E3X A;  3DL1 A;  2ERQ A;  1KUI A;  1R54 A;  2OXW A;  3Q2H A;  1R1I A;  1XM5 A;  1FLS A;  1GKC A;  1B3D A;  1ZXC A;  4DF9 A;  1OO9 A;  966C A;  1CGF A;  1YOU A;  1OS2 A;  1OM8 A;  1BUV M;  2Y6D A;  1SAT A;  456C A;  2DW1 A;  1BQQ M;  1HY7 A;  1XUR A;  1PWV A;  2HU6 A;  1YCM A;  5CZM A;  5I0L A;  3ZVS A;  1KAP P;  2YIG A;  1IAG A;  2KRJ A;  1K7I A;  1QIB A;  1G9K A;  1ZVX A;  1HV5 A;  2MZI A;  3WV3 A;  1A86 A;  1GE6 A;  4IUW A;  3HDB A;  3EDZ A;  1G05 A;  5CXA A;  1KBC A;  1HTD A;  3HY7 A;  3F16 A;  1OMJ A;  1PWW A;  1JAN A;  1C3I A;  4WK7 A;  2L0R A;  5D3C A;  1MMB A;  3LJT A;  1SMP A;  2W12 A;  1JAQ A;  1PWQ A;  3LJZ A;  3UVC A;  3EDI A;  4J4M A;  4AUO A;  2OXZ A;  1UEA A;  2V4B A;  3P24 A;  1KUK A;  3DSL A;  2WOA A;  1UMT A;  3F15 A;  3BA0 A;  3LJG A;  2D1O A;  3LIL A;  2CKI A;  2X3A A;  1IAE A;  3K7L A;  3O64 A;  4XCT A;  1OM6 A;  1BKC I;  5I12 A;  3O2X A;  1S4B P;  3DTK A;  830C A;  4JIJ A;  2JNP A;  2POJ A;  3ELM A;  3L0V A;  2YUF A;  3N2V A;  2K9C A;  4GF1 A;  1FBL A;  1OZ9 A;  1SLN A;  3TVC A;  4DPE A;  2USN A;  3EHY A;  2W0D A;  1CAQ A;  3KMC A;  1ND1 A;  1GE5 A;  3F1A A;  1G49 A;  1D8F A;  2RJQ A;  3I7G A;  1OM7 A;  1TVI A;  4PKV A;  4L63 A;  4WF6 A;  3VTG A;  1UMS A;  1DMT A;  3B92 A;  5I2Z A;  1QJI A;  1QUA A;  3GBO A;  1OS9 A;  1AYK A;  1HFS A;  3KEK A;  1XFY A;  4QKZ A;  5BOY A;  4PKQ A;  1ATL A;  3DNG A;  1B8Y A;  1ZXV A;  4L6T A;  5H8X A;  5B5P A;  3LQ0 A;  1SRP A;  3AIG A;  3CKI A;  1R1H A;  1ROS A;  2JT5 A;  3L0T A;  1XFU A;  3MA2 A;  4H76 A;  4ZR5 A;  5D1T A;  3LUN A;  1MMP A;  1MNC A;  1EAK A;  2A8H A;  3HY9 A;  1Y8J A;  1EUB A;  4Q1L A;  4HMA A;  1R1J A;  3RTT A;  4DD8 A;  4H3X A;  1AF0 A;  2JT6 A;  1KUG A;  3I7I A;  1SU3 A;  3TS4 A;  5BOT A;  2AIG P;  1C7K A;  1ZTQ A;  2OW0 A;  2N8R A;  1YP1 A;  3EDH A;  4GWM A;  1GO7 P;  2DW2 A;  1BM6 A;  4WKI A;  1USN A;  1HOV A;  1Y0V A;  4EFS A;  3KEJ A;  3F17 A;  1JK3 A;  5D7W A;  1IAB A;  1H71 P;  4FVL A;  4GR3 A;  2I47 A;  2OY4 A;  1CXV A;  1RMZ A;  2Y6C A;  1L6J A;  4IN9 A;  4A7B A;  1BIW A;  5I4O A;  1D7X A;  3G42 A;  4H2E A;  1JIW P;  4FXY P;  4HX3 A;  1IAC A;  1XFZ A;  2OW2 A;  3LMC A;  4H82 A;  3RTS A;  3U1R A;  3F18 A;  4AXQ A;  1MMQ A;  2D1N A;  5D1U A;  3DTE A;  4PKU A;  1R55 A;  3LK8 A;  5CUH A;  2CLT A;  1ZS0 A;  2DDY A;  1XFV A;  3EDG A;  5B5O A;  4ILW D;  2RJP A;  2DW0 A;  4FXQ A;  3HBU P;  3LKA A;  4WZV A;  4JA1 A;  2JSD A;  2DDF A;  1JAO A;  1I1I P;  2MZH A;  3K7N A;  3NX7 A;  5LAB A;  1J7N A;  2O36 A;  4XM7 A;  4GR0 A;  2OXU A;  3USN A;  3DWB A;  2J0T A;  4GWN A;  2AYK A;  2OVZ A;  1RM8 A;  2JIH A;  1CQR A;  1I73 A;  5L7F A;  2FV5 A;  1D8M A;  3ZUK A;  4GR8 A;  2E2D A;  2WO9 A;  2X3B A;  3LEA A;  1JKY A;  1MMR A;  2QPJ A;  1EB6 A;  5D1S A;  2J83 A;  3B8Z A;  3AYK A;  4GQL A;  4PKT A;  2O3E A;  3KRY A;  3TSK A;  3TT4 A;  4JQG A;  3AYU A;  3OHO A;  1BUD A;  2SRT A;  4ON1 A;  1XUC A;  1BZS A;  4AIG A;  1Q3A A;  3HDA P;  3KWV C;  3LIK A;  1QIA A;  3LE9 A;  1K7Q A;  3Q2G A;  4XBH A;  2YB9 A;  1IAA A;  4XM6 A;  2X7M A;  2W14 A;  4PKS A;  1GXD A;  2OI0 A;  2PJT A;  4L7A A;  3WV1 A;  1GE7 A;  3F19 A;  1G12 A;  1HFC A;  4A3W A;  1QJJ A;  3E8R A;  2XS3 A;  4JP4 A;  4G0D A;  1KUH A;  1A85 A;  1JJ9 A;  4PKR A;  4H49 A;  3WV2 A;  1ZP5 A;  5I43 A;  1DTH A;  1GO8 P;  1D5J A;  1YQY A;  3KME A;  3LUM A;  1JH1 A;  1Z3J A;  4JPA A;  1SLM A;  3HB2 P;  1K7G A;  3G5C A;  4CTH A;  4I03 A;  2TCL A;  3P1V A;  1O0Q A;  2OW1 A;  1AST A;  1KUF A;  4H1Q A;  1WNI A;  1GKD A;  3VI1 A;  4H84 A;  4PKW A;  1JAP A;  2Z2D A;  4R3V A;  1XFX A;  4G9L A;  1PWP A;  4L19 A;  1G4K A;  3DPF A;  3DTI A;  3SHI A;  4DV8 A;  4IJO A;  2OZR A;  5L79 A; 
#chains in the Genus database with same CATH homology
 3KEC A;  1CGL A;  1CK7 A;  2OVX A;  1JIZ A;  1BSW A;  5I3M A;  1Y93 A;  5D2B A;  5BPA A;  4FU4 A;  2ERO A;  4I35 A;  2FV9 A;  3V96 B;  1I76 A;  2OY2 A;  1XUD A;  1AKL A;  2W15 A;  3ZXH A;  1C8T A;  3B2Z A;  1CGE A;  1BKC A;  4H30 A;  1BQO A;  2MLR A;  1UTT A;  2W13 A;  3N2U A;  4XM8 A;  3EWJ A;  3EHX A;  2MLS A;  2ERP A;  1BKC E;  2WO8 A;  2OW9 A;  3LGP A;  4WKE A;  3DPE A;  3HBV P;  5JMY A;  2X3C A;  1UTZ A;  3OHL A;  4GUY A;  3HYG A;  4AYK A;  3LIR A;  1IAD A;  2XS4 A;  1PWU A;  1O0T A;  1FM1 A;  1QIC A;  2K2G A;  3KHI A;  1XFW A;  1CIZ A;  3LQB A;  2MZE A;  2E3X A;  3DL1 A;  2ERQ A;  1KUI A;  1R54 A;  2OXW A;  3Q2H A;  1R1I A;  1FLS A;  1GKC A;  1B3D A;  1ZXC A;  4DF9 A;  1OO9 A;  966C A;  1CGF A;  1YOU A;  1OS2 A;  1OM8 A;  1BUV M;  2Y6D A;  1SAT A;  456C A;  2DW1 A;  1BQQ M;  1HY7 A;  1XUR A;  1PWV A;  2HU6 A;  1YCM A;  5CZM A;  5I0L A;  3ZVS A;  1KAP P;  2YIG A;  1IAG A;  2KRJ A;  1K7I A;  1QIB A;  1G9K A;  1ZVX A;  1HV5 A;  2MZI A;  3WV3 A;  1A86 A;  1GE6 A;  4IUW A;  3HDB A;  3EDZ A;  1G05 A;  5CXA A;  1KBC A;  1HTD A;  3HY7 A;  3F16 A;  1OMJ A;  1PWW A;  1JAN A;  1C3I A;  4WK7 A;  2L0R A;  5D3C A;  1MMB A;  3LJT A;  1SMP A;  2W12 A;  1JAQ A;  1PWQ A;  3LJZ A;  3UVC A;  3EDI A;  4J4M A;  4AUO A;  2OXZ A;  1UEA A;  2V4B A;  3P24 A;  1KUK A;  3DSL A;  2WOA A;  1UMT A;  3F15 A;  3BA0 A;  3LJG A;  2D1O A;  3LIL A;  2CKI A;  2X3A A;  1IAE A;  3K7L A;  3O64 A;  4XCT A;  1OM6 A;  1BKC I;  5I12 A;  3O2X A;  1S4B P;  3DTK A;  830C A;  4JIJ A;  2JNP A;  2POJ A;  3ELM A;  3L0V A;  2YUF A;  3N2V A;  2K9C A;  4GF1 A;  1FBL A;  1SLN A;  3TVC A;  4DPE A;  2USN A;  3EHY A;  2W0D A;  1CAQ A;  3KMC A;  1ND1 A;  1GE5 A;  3F1A A;  1G49 A;  1D8F A;  2RJQ A;  3I7G A;  1OM7 A;  4PKV A;  4L63 A;  4WF6 A;  3VTG A;  1UMS A;  1DMT A;  3B92 A;  5I2Z A;  1QJI A;  1QUA A;  3GBO A;  1OS9 A;  1AYK A;  1HFS A;  3KEK A;  1XFY A;  4QKZ A;  5BOY A;  4PKQ A;  1ATL A;  3DNG A;  1B8Y A;  1ZXV A;  4L6T A;  5H8X A;  5B5P A;  3LQ0 A;  1SRP A;  3AIG A;  3CKI A;  1R1H A;  1ROS A;  2JT5 A;  3L0T A;  1XFU A;  3MA2 A;  4H76 A;  4ZR5 A;  5D1T A;  3LUN A;  1MMP A;  1MNC A;  1EAK A;  2A8H A;  3HY9 A;  1Y8J A;  1EUB A;  4Q1L A;  4HMA A;  1R1J A;  3RTT A;  4DD8 A;  4H3X A;  1AF0 A;  2JT6 A;  1KUG A;  3I7I A;  1SU3 A;  3TS4 A;  5BOT A;  2AIG P;  1C7K A;  1ZTQ A;  2OW0 A;  2N8R A;  1YP1 A;  3EDH A;  4GWM A;  1GO7 P;  2DW2 A;  1BM6 A;  4WKI A;  1USN A;  1HOV A;  1Y0V A;  4EFS A;  3KEJ A;  3F17 A;  1JK3 A;  5D7W A;  1IAB A;  1H71 P;  4FVL A;  4GR3 A;  2I47 A;  2OY4 A;  1CXV A;  1RMZ A;  2Y6C A;  1L6J A;  4IN9 A;  4A7B A;  1BIW A;  5I4O A;  1D7X A;  3G42 A;  4H2E A;  1JIW P;  4FXY P;  4HX3 A;  1IAC A;  1XFZ A;  2OW2 A;  3LMC A;  4H82 A;  3RTS A;  3U1R A;  3F18 A;  4AXQ A;  1MMQ A;  2D1N A;  5D1U A;  3DTE A;  4PKU A;  1R55 A;  3LK8 A;  5CUH A;  2CLT A;  1ZS0 A;  2DDY A;  1XFV A;  3EDG A;  5B5O A;  4ILW D;  2RJP A;  2DW0 A;  4FXQ A;  3HBU P;  3LKA A;  4WZV A;  4JA1 A;  2JSD A;  2DDF A;  1JAO A;  1I1I P;  2MZH A;  3K7N A;  3NX7 A;  5LAB A;  1J7N A;  2O36 A;  4XM7 A;  4GR0 A;  2OXU A;  3USN A;  3DWB A;  2J0T A;  4GWN A;  2AYK A;  2OVZ A;  1RM8 A;  2JIH A;  1CQR A;  1I73 A;  5L7F A;  2FV5 A;  1D8M A;  3ZUK A;  4GR8 A;  2E2D A;  2WO9 A;  2X3B A;  3LEA A;  1JKY A;  1MMR A;  2QPJ A;  1EB6 A;  5D1S A;  2J83 A;  3B8Z A;  3AYK A;  4GQL A;  4PKT A;  2O3E A;  3KRY A;  3TSK A;  3TT4 A;  4JQG A;  3AYU A;  3OHO A;  1BUD A;  2SRT A;  4ON1 A;  1XUC A;  1BZS A;  4AIG A;  1Q3A A;  3HDA P;  3KWV C;  3LIK A;  1QIA A;  3LE9 A;  1K7Q A;  3Q2G A;  4XBH A;  2YB9 A;  1IAA A;  4XM6 A;  2X7M A;  2W14 A;  4PKS A;  1GXD A;  2OI0 A;  2PJT A;  4L7A A;  3WV1 A;  1GE7 A;  3F19 A;  1G12 A;  1HFC A;  4A3W A;  1QJJ A;  3E8R A;  2XS3 A;  4JP4 A;  4G0D A;  1KUH A;  1A85 A;  1JJ9 A;  4PKR A;  4H49 A;  3WV2 A;  1ZP5 A;  5I43 A;  1DTH A;  1GO8 P;  1D5J A;  1YQY A;  3KME A;  3LUM A;  1JH1 A;  1Z3J A;  4JPA A;  1SLM A;  3HB2 P;  1K7G A;  3G5C A;  4CTH A;  4I03 A;  2TCL A;  3P1V A;  1O0Q A;  2OW1 A;  1AST A;  1KUF A;  4H1Q A;  1WNI A;  1GKD A;  3VI1 A;  4H84 A;  4PKW A;  1JAP A;  2Z2D A;  4R3V A;  1XFX A;  4G9L A;  1PWP A;  4L19 A;  1G4K A;  3DPF A;  3DTI A;  3SHI A;  4DV8 A;  4IJO A;  2OZR A;  5L79 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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