4EFSA

Human mmp12 in complex with l-glutamate motif inhibitor
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
159
structure length
159
Chain Sequence
MGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Simple pseudo-dipeptides with a P2' glutamate: a novel inhibitor family of matrix metalloproteases and other metzincins.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Macrophage metalloelastase
total genus 43
structure length 159
sequence length 159
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2012-03-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 4efsA00
3EHXA 3HYGA 4H84A 1KBCA 3LUMA 1B3DA 1ZS0A 1G9KA 3MA2A 1BKCE 4R3VA 2YB9A 4PKTA 1QIBA 3VI1A 1FLSA 3KEJA 5D7WA 4H1QA 4CTHA 2OY4A 2OXZA 3LE9A 5I3MA 3F18A 1QUAA 4WZVA 3TS4A 1UMSA 1D5JA 1JAQA 1SLNA 1JIZA 1BM6A 2USNA 5BPAA 1Y0VA 3B8ZA 1KAPP 3G42A 4H30A 2ERPA 2MZHA 5LABA 1JKYA 1KUGA 1KUHA 3OHOA 4G9LA 4GR8A 3RTSA 3LJZA 3LIKA 4IN9A 1ASTA 3B2ZA 3K7LA 2DW2A 3EDZA 2OI0A 2XS4A 4WF6A 2KRJA 1IACA 2OZRA 4FU4A 3B92A 1BZSA 1DMTA 2V4BA 1MMBA 2W12A 4QKZA 1HFSA 4XM8A 1UTZA 2X7MA 1H71P 1FM1A 1JAOA 1PWQA 1OS2A 1GO8P 1AYKA 2X3BA 2MLSA 2E3XA 4DV8A 1Y8JA 5CZMA 4FXQA 3OHLA 4H2EA 2JIHA 1L6JA 1EUBA 3O2XA 2CKIA 1WNIA 4PKSA 2W14A 2OW1A 3I7IA 2OXUA 1XFZA 3K7NA 1OM7A 2O3EA 3Q2GA 3HY7A 5H8XA 1ZXVA 2AIGP 1ZVXA 2Y6CA 2ERQA 2RJQA 3UVCA 4PKVA 1O0TA 1C8TA 1BKCI 3EHYA 1J7NA 1GKDA 4DD8A 1SATA 1FBLA 1D8FA 2J0TA 3LGPA 1YCMA 2WOAA 1MNCA 4WKIA 1C3IA 1HOVA 3ZXHA 3DSLA 1QJIA 3WV2A 1SLMA 1JAPA 3F16A 5D2BA 2W15A 4AYKA 1IABA 4AXQA 1KUFA 1Q3AA 1MMPA 2FV9A 1I73A 3G5CA 4PKRA 1EAKA 1OM6A 4DPEA 1R55A 966CA 2XS3A 5D1UA 2SRTA 1G4KA 3O64A 1CGFA 1AKLA 1JANA 1YP1A 3KEKA 4FXYP 5CUHA 1YQYA 5D3CA 5JMYA 3L0TA 3P24A 1R1IA 3F1AA 3TT4A 2DW1A 3NX7A 4EFSA 3E8RA 4JQGA 1SU3A 1I76A 1K7QA 1JK3A 1YOUA 1SRPA 1XURA 4H76A 3EWJA 3VTGA 5L79A 3KMCA 4DF9A 1GKCA 4H49A 3LJTA 1BIWA 2O36A 4WKEA 1HV5A 1DTHA 1K7GA 3DPFA 2JT6A 3KECA 3I7GA 3HDAP 2JT5A 3L0VA 1R1JA 2DDYA 1HY7A 3HBUP 4A7BA 1MMRA 5I2ZA 4GR0A 5D1TA 1IAEA 1PWPA 3SHIA 5I43A 3HB2P 2OVZA 5D1SA 2AYKA 5L7FA 2OVXA 4IUWA 3LK8A 1ATLA 4PKUA 4XCTA 1QJJA 4XM6A 4H3XA 1JIWP 1AF0A 3LKAA 5I12A 4XM7A 1MMQA 1ROSA 3HY9A 5B5PA 2DW0A 3AYUA 2MZEA 4GF1A 1GO7P 1D7XA 3DPEA 2A8HA 1A86A 3N2VA 2Z2DA 1HTDA 4HX3A 3TSKA 1XFXA 2OW2A 4GUYA 3Q2HA 1USNA 3U1RA 1CXVA 1K7IA 4PKWA 1GE6A 1CK7A 1Y93A 2J83A 1A85A 2X3CA 4AIGA 1GE5A 1XFVA 4G0DA 1Z3JA 2POJA 4AUOA 4L63A 1G49A 1OO9A 3P1VA 2K9CA 4XBHA 1KUIA 1S4BP 2OW9A 3BA0A 3DL1A 3WV3A 1G12A 1CGLA 1QIAA 1OMJA 3TVCA 1XFWA 1JH1A 1GE7A 2WO9A 3LQ0A 4H82A 1BUDA 4ZR5A 4JP4A 3WV1A 3DNGA 1I1IP 3EDIA 4J4MA 3EDHA 3LEAA 4GWNA 4I03A 3DWBA 3KHIA 2E2DA 1GXDA 1HFCA 4A3WA 4I35A 2YIGA 2JSDA 2RJPA 2D1NA 2W0DA 1PWVA 4PKQA 5B5OA 1PWWA 1R54A 4L6TA 5I4OA 456CA 1IAAA 1CAQA 4WK7A 1PWUA 1ZXCA 3HBVP 3AYKA 4FVLA 2DDFA 2CLTA 4IJOA 1SMPA 3LUNA 2N8RA 2OXWA 2PJTA 4GWMA 1RMZA 4ILWD 5I0LA 4GR3A 4L19A 830CA 3F19A 1XFUA 3ZVSA 5CXAA 1CQRA 3LIRA 3KMEA 1ND1A 3CKIA 3LMCA 1R1HA 2FV5A 3GBOA 1EB6A 5BOYA 2TCLA 4JA1A 1KUKA 1BKCA 3F17A 2MLRA 1UTTA 2WO8A 2L0RA 2W13A 3KRYA 1BSWA 3LQBA 4HMAA 4JPAA 1RM8A 1B8YA 1XFYA 2X3AA 2OY2A 1XUDA 3N2UA 1UMTA 4ON1A 3F15A 2D1OA 2OW0A 2HU6A 1G05A 3HDBA 1ZTQA 1QICA 1BUVM 2JNPA 2Y6DA 3KWVC 3LILA 1JJ9A 1OM8A 5BOTA 1C7KA 4JIJA 3USNA 1CGEA 2EROA 3AIGA 1IAGA 4GQLA 2K2GA 2I47A 1BQQM 3ELMA 2MZIA 1CIZA 1O0QA 1XUCA 1UEAA 1ZP5A 2QPJA 1D8MA 1IADA 1OS9A 1BQOA 3V96B 3ZUKA 3RTTA 3LJGA 4Q1LA 3EDGA
chains in the Genus database with same CATH superfamily
3EHXA 3HYGA 4H84A 1KBCA 3LUMA 1B3DA 1ZS0A 1G9KA 3MA2A 1BKCE 4R3VA 2YB9A 4PKTA 1QIBA 3VI1A 1FLSA 3KEJA 5D7WA 4H1QA 4CTHA 2OY4A 2OXZA 3LE9A 5I3MA 3F18A 1QUAA 4WZVA 3TS4A 1UMSA 1D5JA 1JAQA 1SLNA 1XAXA 1JIZA 1BM6A 2USNA 5BPAA 1Y0VA 3B8ZA 1KAPP 3G42A 4H30A 2ERPA 2MZHA 5LABA 1JKYA 1KUGA 1KUHA 3OHOA 4G9LA 4GR8A 3RTSA 3LJZA 3LIKA 4IN9A 1ASTA 3B2ZA 3K7LA 2DW2A 3EDZA 2OI0A 2XS4A 4WF6A 2KRJA 1IACA 2OZRA 4FU4A 3B92A 1BZSA 1DMTA 2V4BA 1MMBA 2W12A 4QKZA 1HFSA 4XM8A 1UTZA 2X7MA 1H71P 1FM1A 1JAOA 1PWQA 1OS2A 1GO8P 1AYKA 2X3BA 2MLSA 2E3XA 4DV8A 1Y8JA 5CZMA 4FXQA 3OHLA 4H2EA 2JIHA 1L6JA 1EUBA 3O2XA 2CKIA 1WNIA 4PKSA 2W14A 2OW1A 3I7IA 2OXUA 1XFZA 3K7NA 1OM7A 2O3EA 3Q2GA 3HY7A 5H8XA 1ZXVA 2AIGP 1ZVXA 2Y6CA 2ERQA 2RJQA 3UVCA 4PKVA 1O0TA 1C8TA 1BKCI 3EHYA 1J7NA 1GKDA 3DTKA 4DD8A 1SATA 1FBLA 1D8FA 2J0TA 3LGPA 1YCMA 2WOAA 1MNCA 4WKIA 1C3IA 1HOVA 3ZXHA 3DSLA 1QJIA 3WV2A 1SLMA 1JAPA 3F16A 5D2BA 2W15A 4AYKA 1IABA 4AXQA 1KUFA 1Q3AA 1MMPA 2FV9A 1I73A 3G5CA 4PKRA 1EAKA 1OM6A 4DPEA 1R55A 966CA 2XS3A 5D1UA 2SRTA 1G4KA 3O64A 1CGFA 1AKLA 1JANA 1YP1A 3DTIA 3KEKA 4FXYP 5CUHA 1YQYA 5D3CA 3DTEA 5JMYA 3L0TA 3P24A 1R1IA 3F1AA 3TT4A 2DW1A 3NX7A 4EFSA 3E8RA 4JQGA 1SU3A 1I76A 1K7QA 1JK3A 1YOUA 1SRPA 1XURA 4H76A 3EWJA 3VTGA 5L79A 3KMCA 4DF9A 1GKCA 4H49A 3LJTA 1BIWA 2O36A 4WKEA 1HV5A 1DTHA 1K7GA 3DPFA 2JT6A 3KECA 3I7GA 2YUFA 3HDAP 2JT5A 3L0VA 1R1JA 2DDYA 1HY7A 3HBUP 4A7BA 1MMRA 5I2ZA 4GR0A 5D1TA 1IAEA 1PWPA 3SHIA 5I43A 3HB2P 2OVZA 5D1SA 2AYKA 5L7FA 2OVXA 4IUWA 3LK8A 1ATLA 4PKUA 4XCTA 1QJJA 4XM6A 4H3XA 1JIWP 1AF0A 3LKAA 5I12A 4XM7A 1MMQA 1ROSA 3HY9A 5B5PA 2DW0A 3AYUA 2MZEA 4GF1A 1GO7P 1D7XA 3DPEA 2A8HA 1A86A 3N2VA 2Z2DA 1HTDA 4HX3A 3TSKA 1XFXA 2OW2A 4GUYA 3Q2HA 1USNA 3U1RA 1CXVA 1K7IA 4PKWA 1GE6A 1CK7A 1Y93A 2J83A 1A85A 2X3CA 4AIGA 1GE5A 1XFVA 4G0DA 1Z3JA 2POJA 4AUOA 4L63A 1G49A 1OO9A 3P1VA 2K9CA 4XBHA 1KUIA 1S4BP 2OW9A 3BA0A 3DL1A 3WV3A 1G12A 1CGLA 1QIAA 1OMJA 3TVCA 1XFWA 1JH1A 1GE7A 2WO9A 3LQ0A 4H82A 1BUDA 4ZR5A 4JP4A 3WV1A 3DNGA 1I1IP 3EDIA 4J4MA 3EDHA 3LEAA 4GWNA 4I03A 3DWBA 3KHIA 2E2DA 1GXDA 1HFCA 4A3WA 4I35A 2YIGA 2JSDA 2RJPA 2D1NA 2W0DA 1PWVA 4PKQA 5B5OA 1PWWA 1R54A 4L6TA 5I4OA 456CA 1IAAA 1CAQA 4WK7A 1PWUA 1ZXCA 3HBVP 3AYKA 4FVLA 2DDFA 2CLTA 4IJOA 1SMPA 3LUNA 2N8RA 2OXWA 2PJTA 4GWMA 1RMZA 4ILWD 5I0LA 4GR3A 4L19A 830CA 3F19A 1XFUA 1TVIA 1OZ9A 3ZVSA 5CXAA 1CQRA 3LIRA 3KMEA 1ND1A 3CKIA 3LMCA 1R1HA 2FV5A 3GBOA 1EB6A 5BOYA 2TCLA 4JA1A 1KUKA 1BKCA 3F17A 2MLRA 1UTTA 2WO8A 2L0RA 2W13A 3KRYA 1BSWA 3LQBA 4HMAA 4JPAA 1RM8A 1B8YA 1XFYA 2X3AA 2OY2A 1XUDA 3N2UA 1UMTA 4ON1A 3F15A 2D1OA 2OW0A 2HU6A 1G05A 3HDBA 1ZTQA 1QICA 1BUVM 2JNPA 2Y6DA 3KWVC 3LILA 1JJ9A 1OM8A 5BOTA 1C7KA 4JIJA 3USNA 1CGEA 4L7AA 2EROA 3AIGA 1IAGA 4GQLA 2K2GA 2I47A 1BQQM 3ELMA 2MZIA 1CIZA 1O0QA 1XUCA 1UEAA 1ZP5A 2QPJA 1D8MA 1IADA 1OS9A 1BQOA 3V96B 3ZUKA 3RTTA 3LJGA 1XM5A 4Q1LA 3EDGA
chains in the Genus database with same CATH topology
3EHXA 3HYGA 4H84A 1KBCA 3LUMA 1B3DA 1ZS0A 1G9KA 3MA2A 1BKCE 4R3VA 2YB9A 4PKTA 1QIBA 3VI1A 1FLSA 3KEJA 5D7WA 4H1QA 4CTHA 2OY4A 2OXZA 3LE9A 5I3MA 3F18A 1QUAA 4WZVA 3TS4A 1UMSA 1D5JA 1JAQA 1SLNA 1JIZA 1BM6A 2USNA 5BPAA 1Y0VA 3B8ZA 1KAPP 3G42A 4H30A 2ERPA 2MZHA 5LABA 1JKYA 1KUGA 1KUHA 3OHOA 4G9LA 4GR8A 3RTSA 3LJZA 3LIKA 4IN9A 1ASTA 3B2ZA 3K7LA 2DW2A 3EDZA 2OI0A 2XS4A 4WF6A 2KRJA 1IACA 2OZRA 4FU4A 3B92A 1BZSA 1DMTA 2V4BA 1MMBA 2W12A 4QKZA 1HFSA 4XM8A 1UTZA 2X7MA 1H71P 1FM1A 1JAOA 1PWQA 1OS2A 1GO8P 1AYKA 2X3BA 2MLSA 2E3XA 4DV8A 1Y8JA 5CZMA 4FXQA 3OHLA 4H2EA 2JIHA 1L6JA 1EUBA 3O2XA 2CKIA 1WNIA 4PKSA 2W14A 2OW1A 3I7IA 2OXUA 1XFZA 3K7NA 1OM7A 2O3EA 3Q2GA 3HY7A 5H8XA 1ZXVA 2AIGP 1ZVXA 2Y6CA 2ERQA 2RJQA 3UVCA 4PKVA 1O0TA 1C8TA 1BKCI 3EHYA 1J7NA 1GKDA 3DTKA 4DD8A 1SATA 1FBLA 1D8FA 2J0TA 3LGPA 1YCMA 2WOAA 1MNCA 4WKIA 1C3IA 1HOVA 3ZXHA 3DSLA 1QJIA 3WV2A 1SLMA 1JAPA 3F16A 5D2BA 2W15A 4AYKA 1IABA 4AXQA 1KUFA 1Q3AA 1MMPA 2FV9A 1I73A 3G5CA 4PKRA 1EAKA 1OM6A 4DPEA 1R55A 966CA 2XS3A 5D1UA 2SRTA 1G4KA 3O64A 1CGFA 1AKLA 1JANA 1YP1A 3DTIA 3KEKA 4FXYP 5CUHA 1YQYA 5D3CA 3DTEA 5JMYA 3L0TA 3P24A 1R1IA 3F1AA 3TT4A 2DW1A 3NX7A 4EFSA 3E8RA 4JQGA 1SU3A 1I76A 1K7QA 1JK3A 1YOUA 1SRPA 1XURA 4H76A 3EWJA 3VTGA 5L79A 3KMCA 4DF9A 1GKCA 4H49A 3LJTA 1BIWA 2O36A 4WKEA 1HV5A 1DTHA 1K7GA 3DPFA 2JT6A 3KECA 3I7GA 2YUFA 3HDAP 2JT5A 3L0VA 1R1JA 2DDYA 1HY7A 3HBUP 4A7BA 1MMRA 5I2ZA 4GR0A 5D1TA 1IAEA 1PWPA 3SHIA 5I43A 3HB2P 2OVZA 5D1SA 2AYKA 5L7FA 2OVXA 4IUWA 3LK8A 1ATLA 4PKUA 4XCTA 1QJJA 4XM6A 4H3XA 1JIWP 1AF0A 3LKAA 5I12A 4XM7A 1MMQA 1ROSA 3HY9A 5B5PA 2DW0A 3AYUA 2MZEA 4GF1A 1GO7P 1D7XA 3DPEA 2A8HA 1A86A 3N2VA 2Z2DA 1HTDA 4HX3A 3TSKA 1XFXA 2OW2A 4GUYA 3Q2HA 1USNA 3U1RA 1CXVA 1K7IA 4PKWA 1GE6A 1CK7A 1Y93A 2J83A 1A85A 2X3CA 4AIGA 1GE5A 1XFVA 4G0DA 1Z3JA 2POJA 4AUOA 4L63A 1G49A 1OO9A 3P1VA 2K9CA 4XBHA 1KUIA 1S4BP 2OW9A 3BA0A 3DL1A 3WV3A 1G12A 1CGLA 1QIAA 1OMJA 3TVCA 1XFWA 1JH1A 1GE7A 2WO9A 3LQ0A 4H82A 1BUDA 4ZR5A 4JP4A 3WV1A 3DNGA 1I1IP 3EDIA 4J4MA 3EDHA 3LEAA 4GWNA 4I03A 3DWBA 3KHIA 2E2DA 1GXDA 1HFCA 4A3WA 4I35A 2YIGA 2JSDA 2RJPA 2D1NA 2W0DA 1PWVA 4PKQA 5B5OA 1PWWA 1R54A 4L6TA 5I4OA 456CA 1IAAA 1CAQA 4WK7A 1PWUA 1ZXCA 3HBVP 3AYKA 4FVLA 2DDFA 2CLTA 4IJOA 1SMPA 3LUNA 2N8RA 2OXWA 2PJTA 4GWMA 1RMZA 4ILWD 5I0LA 4GR3A 4L19A 830CA 3F19A 1XFUA 3ZVSA 5CXAA 1CQRA 3LIRA 3KMEA 1ND1A 3CKIA 3LMCA 1R1HA 2FV5A 3GBOA 1EB6A 5BOYA 2TCLA 4JA1A 1KUKA 1BKCA 3F17A 2MLRA 1UTTA 2WO8A 2L0RA 2W13A 3KRYA 1BSWA 3LQBA 4HMAA 4JPAA 1RM8A 1B8YA 1XFYA 2X3AA 2OY2A 1XUDA 3N2UA 1UMTA 4ON1A 3F15A 2D1OA 2OW0A 2HU6A 1G05A 3HDBA 1ZTQA 1QICA 1BUVM 2JNPA 2Y6DA 3KWVC 3LILA 1JJ9A 1OM8A 5BOTA 1C7KA 4JIJA 3USNA 1CGEA 4L7AA 2EROA 3AIGA 1IAGA 4GQLA 2K2GA 2I47A 1BQQM 3ELMA 2MZIA 1CIZA 1O0QA 1XUCA 1UEAA 1ZP5A 2QPJA 1D8MA 1IADA 1OS9A 1BQOA 3V96B 3ZUKA 3RTTA 3LJGA 4Q1LA 3EDGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EHX A;  3HYG A;  4H84 A;  1KBC A;  3LUM A;  1B3D A;  1ZS0 A;  1G9K A;  3MA2 A;  1BKC E;  4R3V A;  2YB9 A;  4PKT A;  1QIB A;  3VI1 A;  1FLS A;  3KEJ A;  5D7W A;  4H1Q A;  4CTH A;  2OY4 A;  2OXZ A;  3LE9 A;  5I3M A;  3F18 A;  1QUA A;  4WZV A;  3TS4 A;  1UMS A;  1D5J A;  1JAQ A;  1SLN A;  1JIZ A;  1BM6 A;  2USN A;  5BPA A;  1Y0V A;  3B8Z A;  1KAP P;  3G42 A;  4H30 A;  2ERP A;  2MZH A;  5LAB A;  1JKY A;  1KUG A;  1KUH A;  3OHO A;  4G9L A;  4GR8 A;  3RTS A;  3LJZ A;  3LIK A;  4IN9 A;  1AST A;  3B2Z A;  3K7L A;  2DW2 A;  3EDZ A;  2OI0 A;  2XS4 A;  4WF6 A;  2KRJ A;  1IAC A;  2OZR A;  4FU4 A;  3B92 A;  1BZS A;  1DMT A;  2V4B A;  1MMB A;  2W12 A;  4QKZ A;  1HFS A;  4XM8 A;  1UTZ A;  2X7M A;  1H71 P;  1FM1 A;  1JAO A;  1PWQ A;  1OS2 A;  1GO8 P;  1AYK A;  2X3B A;  2MLS A;  2E3X A;  4DV8 A;  1Y8J A;  5CZM A;  4FXQ A;  3OHL A;  4H2E A;  2JIH A;  1L6J A;  1EUB A;  3O2X A;  2CKI A;  1WNI A;  4PKS A;  2W14 A;  2OW1 A;  3I7I A;  2OXU A;  1XFZ A;  3K7N A;  1OM7 A;  2O3E A;  3Q2G A;  3HY7 A;  5H8X A;  1ZXV A;  2AIG P;  1ZVX A;  2Y6C A;  2ERQ A;  2RJQ A;  3UVC A;  4PKV A;  1O0T A;  1C8T A;  1BKC I;  3EHY A;  1J7N A;  1GKD A;  4DD8 A;  1SAT A;  1FBL A;  1D8F A;  2J0T A;  3LGP A;  1YCM A;  2WOA A;  1MNC A;  4WKI A;  1C3I A;  1HOV A;  3ZXH A;  3DSL A;  1QJI A;  3WV2 A;  1SLM A;  1JAP A;  3F16 A;  5D2B A;  2W15 A;  4AYK A;  1IAB A;  4AXQ A;  1KUF A;  1Q3A A;  1MMP A;  2FV9 A;  1I73 A;  3G5C A;  4PKR A;  1EAK A;  1OM6 A;  4DPE A;  1R55 A;  966C A;  2XS3 A;  5D1U A;  2SRT A;  1G4K A;  3O64 A;  1CGF A;  1AKL A;  1JAN A;  1YP1 A;  3KEK A;  4FXY P;  5CUH A;  1YQY A;  5D3C A;  5JMY A;  3L0T A;  3P24 A;  1R1I A;  3F1A A;  3TT4 A;  2DW1 A;  3NX7 A;  4EFS A;  3E8R A;  4JQG A;  1SU3 A;  1I76 A;  1K7Q A;  1JK3 A;  1YOU A;  1SRP A;  1XUR A;  4H76 A;  3EWJ A;  3VTG A;  5L79 A;  3KMC A;  4DF9 A;  1GKC A;  4H49 A;  3LJT A;  1BIW A;  2O36 A;  4WKE A;  1HV5 A;  1DTH A;  1K7G A;  3DPF A;  2JT6 A;  3KEC A;  3I7G A;  3HDA P;  2JT5 A;  3L0V A;  1R1J A;  2DDY A;  1HY7 A;  3HBU P;  4A7B A;  1MMR A;  5I2Z A;  4GR0 A;  5D1T A;  1IAE A;  1PWP A;  3SHI A;  5I43 A;  3HB2 P;  2OVZ A;  5D1S A;  2AYK A;  5L7F A;  2OVX A;  4IUW A;  3LK8 A;  1ATL A;  4PKU A;  4XCT A;  1QJJ A;  4XM6 A;  4H3X A;  1JIW P;  1AF0 A;  3LKA A;  5I12 A;  4XM7 A;  1MMQ A;  1ROS A;  3HY9 A;  5B5P A;  2DW0 A;  3AYU A;  2MZE A;  4GF1 A;  1GO7 P;  1D7X A;  3DPE A;  2A8H A;  1A86 A;  3N2V A;  2Z2D A;  1HTD A;  4HX3 A;  3TSK A;  1XFX A;  2OW2 A;  4GUY A;  3Q2H A;  1USN A;  3U1R A;  1CXV A;  1K7I A;  4PKW A;  1GE6 A;  1CK7 A;  1Y93 A;  2J83 A;  1A85 A;  2X3C A;  4AIG A;  1GE5 A;  1XFV A;  4G0D A;  1Z3J A;  2POJ A;  4AUO A;  4L63 A;  1G49 A;  1OO9 A;  3P1V A;  2K9C A;  4XBH A;  1KUI A;  1S4B P;  2OW9 A;  3BA0 A;  3DL1 A;  3WV3 A;  1G12 A;  1CGL A;  1QIA A;  1OMJ A;  3TVC A;  1XFW A;  1JH1 A;  1GE7 A;  2WO9 A;  3LQ0 A;  4H82 A;  1BUD A;  4ZR5 A;  4JP4 A;  3WV1 A;  3DNG A;  1I1I P;  3EDI A;  4J4M A;  3EDH A;  3LEA A;  4GWN A;  4I03 A;  3DWB A;  3KHI A;  2E2D A;  1GXD A;  1HFC A;  4A3W A;  4I35 A;  2YIG A;  2JSD A;  2RJP A;  2D1N A;  2W0D A;  1PWV A;  4PKQ A;  5B5O A;  1PWW A;  1R54 A;  4L6T A;  5I4O A;  456C A;  1IAA A;  1CAQ A;  4WK7 A;  1PWU A;  1ZXC A;  3HBV P;  3AYK A;  4FVL A;  2DDF A;  2CLT A;  4IJO A;  1SMP A;  3LUN A;  2N8R A;  2OXW A;  2PJT A;  4GWM A;  1RMZ A;  4ILW D;  5I0L A;  4GR3 A;  4L19 A;  830C A;  3F19 A;  1XFU A;  3ZVS A;  5CXA A;  1CQR A;  3LIR A;  3KME A;  1ND1 A;  3CKI A;  3LMC A;  1R1H A;  2FV5 A;  3GBO A;  1EB6 A;  5BOY A;  2TCL A;  4JA1 A;  1KUK A;  1BKC A;  3F17 A;  2MLR A;  1UTT A;  2WO8 A;  2L0R A;  2W13 A;  3KRY A;  1BSW A;  3LQB A;  4HMA A;  4JPA A;  1RM8 A;  1B8Y A;  1XFY A;  2X3A A;  2OY2 A;  1XUD A;  3N2U A;  1UMT A;  4ON1 A;  3F15 A;  2D1O A;  2OW0 A;  2HU6 A;  1G05 A;  3HDB A;  1ZTQ A;  1QIC A;  1BUV M;  2JNP A;  2Y6D A;  3KWV C;  3LIL A;  1JJ9 A;  1OM8 A;  5BOT A;  1C7K A;  4JIJ A;  3USN A;  1CGE A;  2ERO A;  3AIG A;  1IAG A;  4GQL A;  2K2G A;  2I47 A;  1BQQ M;  3ELM A;  2MZI A;  1CIZ A;  1O0Q A;  1XUC A;  1UEA A;  1ZP5 A;  2QPJ A;  1D8M A;  1IAD A;  1OS9 A;  1BQO A;  3V96 B;  3ZUK A;  3RTT A;  3LJG A;  4Q1L A;  3EDG A; 
#chains in the Genus database with same CATH topology
 3EHX A;  3HYG A;  4H84 A;  1KBC A;  3LUM A;  1B3D A;  1ZS0 A;  1G9K A;  3MA2 A;  1BKC E;  4R3V A;  2YB9 A;  4PKT A;  1QIB A;  3VI1 A;  1FLS A;  3KEJ A;  5D7W A;  4H1Q A;  4CTH A;  2OY4 A;  2OXZ A;  3LE9 A;  5I3M A;  3F18 A;  1QUA A;  4WZV A;  3TS4 A;  1UMS A;  1D5J A;  1JAQ A;  1SLN A;  1XAX A;  1JIZ A;  1BM6 A;  2USN A;  5BPA A;  1Y0V A;  3B8Z A;  1KAP P;  3G42 A;  4H30 A;  2ERP A;  2MZH A;  5LAB A;  1JKY A;  1KUG A;  1KUH A;  3OHO A;  4G9L A;  4GR8 A;  3RTS A;  3LJZ A;  3LIK A;  4IN9 A;  1AST A;  3B2Z A;  3K7L A;  2DW2 A;  3EDZ A;  2OI0 A;  2XS4 A;  4WF6 A;  2KRJ A;  1IAC A;  2OZR A;  4FU4 A;  3B92 A;  1BZS A;  1DMT A;  2V4B A;  1MMB A;  2W12 A;  4QKZ A;  1HFS A;  4XM8 A;  1UTZ A;  2X7M A;  1H71 P;  1FM1 A;  1JAO A;  1PWQ A;  1OS2 A;  1GO8 P;  1AYK A;  2X3B A;  2MLS A;  2E3X A;  4DV8 A;  1Y8J A;  5CZM A;  4FXQ A;  3OHL A;  4H2E A;  2JIH A;  1L6J A;  1EUB A;  3O2X A;  2CKI A;  1WNI A;  4PKS A;  2W14 A;  2OW1 A;  3I7I A;  2OXU A;  1XFZ A;  3K7N A;  1OM7 A;  2O3E A;  3Q2G A;  3HY7 A;  5H8X A;  1ZXV A;  2AIG P;  1ZVX A;  2Y6C A;  2ERQ A;  2RJQ A;  3UVC A;  4PKV A;  1O0T A;  1C8T A;  1BKC I;  3EHY A;  1J7N A;  1GKD A;  3DTK A;  4DD8 A;  1SAT A;  1FBL A;  1D8F A;  2J0T A;  3LGP A;  1YCM A;  2WOA A;  1MNC A;  4WKI A;  1C3I A;  1HOV A;  3ZXH A;  3DSL A;  1QJI A;  3WV2 A;  1SLM A;  1JAP A;  3F16 A;  5D2B A;  2W15 A;  4AYK A;  1IAB A;  4AXQ A;  1KUF A;  1Q3A A;  1MMP A;  2FV9 A;  1I73 A;  3G5C A;  4PKR A;  1EAK A;  1OM6 A;  4DPE A;  1R55 A;  966C A;  2XS3 A;  5D1U A;  2SRT A;  1G4K A;  3O64 A;  1CGF A;  1AKL A;  1JAN A;  1YP1 A;  3DTI A;  3KEK A;  4FXY P;  5CUH A;  1YQY A;  5D3C A;  3DTE A;  5JMY A;  3L0T A;  3P24 A;  1R1I A;  3F1A A;  3TT4 A;  2DW1 A;  3NX7 A;  4EFS A;  3E8R A;  4JQG A;  1SU3 A;  1I76 A;  1K7Q A;  1JK3 A;  1YOU A;  1SRP A;  1XUR A;  4H76 A;  3EWJ A;  3VTG A;  5L79 A;  3KMC A;  4DF9 A;  1GKC A;  4H49 A;  3LJT A;  1BIW A;  2O36 A;  4WKE A;  1HV5 A;  1DTH A;  1K7G A;  3DPF A;  2JT6 A;  3KEC A;  3I7G A;  2YUF A;  3HDA P;  2JT5 A;  3L0V A;  1R1J A;  2DDY A;  1HY7 A;  3HBU P;  4A7B A;  1MMR A;  5I2Z A;  4GR0 A;  5D1T A;  1IAE A;  1PWP A;  3SHI A;  5I43 A;  3HB2 P;  2OVZ A;  5D1S A;  2AYK A;  5L7F A;  2OVX A;  4IUW A;  3LK8 A;  1ATL A;  4PKU A;  4XCT A;  1QJJ A;  4XM6 A;  4H3X A;  1JIW P;  1AF0 A;  3LKA A;  5I12 A;  4XM7 A;  1MMQ A;  1ROS A;  3HY9 A;  5B5P A;  2DW0 A;  3AYU A;  2MZE A;  4GF1 A;  1GO7 P;  1D7X A;  3DPE A;  2A8H A;  1A86 A;  3N2V A;  2Z2D A;  1HTD A;  4HX3 A;  3TSK A;  1XFX A;  2OW2 A;  4GUY A;  3Q2H A;  1USN A;  3U1R A;  1CXV A;  1K7I A;  4PKW A;  1GE6 A;  1CK7 A;  1Y93 A;  2J83 A;  1A85 A;  2X3C A;  4AIG A;  1GE5 A;  1XFV A;  4G0D A;  1Z3J A;  2POJ A;  4AUO A;  4L63 A;  1G49 A;  1OO9 A;  3P1V A;  2K9C A;  4XBH A;  1KUI A;  1S4B P;  2OW9 A;  3BA0 A;  3DL1 A;  3WV3 A;  1G12 A;  1CGL A;  1QIA A;  1OMJ A;  3TVC A;  1XFW A;  1JH1 A;  1GE7 A;  2WO9 A;  3LQ0 A;  4H82 A;  1BUD A;  4ZR5 A;  4JP4 A;  3WV1 A;  3DNG A;  1I1I P;  3EDI A;  4J4M A;  3EDH A;  3LEA A;  4GWN A;  4I03 A;  3DWB A;  3KHI A;  2E2D A;  1GXD A;  1HFC A;  4A3W A;  4I35 A;  2YIG A;  2JSD A;  2RJP A;  2D1N A;  2W0D A;  1PWV A;  4PKQ A;  5B5O A;  1PWW A;  1R54 A;  4L6T A;  5I4O A;  456C A;  1IAA A;  1CAQ A;  4WK7 A;  1PWU A;  1ZXC A;  3HBV P;  3AYK A;  4FVL A;  2DDF A;  2CLT A;  4IJO A;  1SMP A;  3LUN A;  2N8R A;  2OXW A;  2PJT A;  4GWM A;  1RMZ A;  4ILW D;  5I0L A;  4GR3 A;  4L19 A;  830C A;  3F19 A;  1XFU A;  1TVI A;  1OZ9 A;  3ZVS A;  5CXA A;  1CQR A;  3LIR A;  3KME A;  1ND1 A;  3CKI A;  3LMC A;  1R1H A;  2FV5 A;  3GBO A;  1EB6 A;  5BOY A;  2TCL A;  4JA1 A;  1KUK A;  1BKC A;  3F17 A;  2MLR A;  1UTT A;  2WO8 A;  2L0R A;  2W13 A;  3KRY A;  1BSW A;  3LQB A;  4HMA A;  4JPA A;  1RM8 A;  1B8Y A;  1XFY A;  2X3A A;  2OY2 A;  1XUD A;  3N2U A;  1UMT A;  4ON1 A;  3F15 A;  2D1O A;  2OW0 A;  2HU6 A;  1G05 A;  3HDB A;  1ZTQ A;  1QIC A;  1BUV M;  2JNP A;  2Y6D A;  3KWV C;  3LIL A;  1JJ9 A;  1OM8 A;  5BOT A;  1C7K A;  4JIJ A;  3USN A;  1CGE A;  4L7A A;  2ERO A;  3AIG A;  1IAG A;  4GQL A;  2K2G A;  2I47 A;  1BQQ M;  3ELM A;  2MZI A;  1CIZ A;  1O0Q A;  1XUC A;  1UEA A;  1ZP5 A;  2QPJ A;  1D8M A;  1IAD A;  1OS9 A;  1BQO A;  3V96 B;  3ZUK A;  3RTT A;  3LJG A;  1XM5 A;  4Q1L A;  3EDG A; 
#chains in the Genus database with same CATH homology
 3EHX A;  3HYG A;  4H84 A;  1KBC A;  3LUM A;  1B3D A;  1ZS0 A;  1G9K A;  3MA2 A;  1BKC E;  4R3V A;  2YB9 A;  4PKT A;  1QIB A;  3VI1 A;  1FLS A;  3KEJ A;  5D7W A;  4H1Q A;  4CTH A;  2OY4 A;  2OXZ A;  3LE9 A;  5I3M A;  3F18 A;  1QUA A;  4WZV A;  3TS4 A;  1UMS A;  1D5J A;  1JAQ A;  1SLN A;  1JIZ A;  1BM6 A;  2USN A;  5BPA A;  1Y0V A;  3B8Z A;  1KAP P;  3G42 A;  4H30 A;  2ERP A;  2MZH A;  5LAB A;  1JKY A;  1KUG A;  1KUH A;  3OHO A;  4G9L A;  4GR8 A;  3RTS A;  3LJZ A;  3LIK A;  4IN9 A;  1AST A;  3B2Z A;  3K7L A;  2DW2 A;  3EDZ A;  2OI0 A;  2XS4 A;  4WF6 A;  2KRJ A;  1IAC A;  2OZR A;  4FU4 A;  3B92 A;  1BZS A;  1DMT A;  2V4B A;  1MMB A;  2W12 A;  4QKZ A;  1HFS A;  4XM8 A;  1UTZ A;  2X7M A;  1H71 P;  1FM1 A;  1JAO A;  1PWQ A;  1OS2 A;  1GO8 P;  1AYK A;  2X3B A;  2MLS A;  2E3X A;  4DV8 A;  1Y8J A;  5CZM A;  4FXQ A;  3OHL A;  4H2E A;  2JIH A;  1L6J A;  1EUB A;  3O2X A;  2CKI A;  1WNI A;  4PKS A;  2W14 A;  2OW1 A;  3I7I A;  2OXU A;  1XFZ A;  3K7N A;  1OM7 A;  2O3E A;  3Q2G A;  3HY7 A;  5H8X A;  1ZXV A;  2AIG P;  1ZVX A;  2Y6C A;  2ERQ A;  2RJQ A;  3UVC A;  4PKV A;  1O0T A;  1C8T A;  1BKC I;  3EHY A;  1J7N A;  1GKD A;  3DTK A;  4DD8 A;  1SAT A;  1FBL A;  1D8F A;  2J0T A;  3LGP A;  1YCM A;  2WOA A;  1MNC A;  4WKI A;  1C3I A;  1HOV A;  3ZXH A;  3DSL A;  1QJI A;  3WV2 A;  1SLM A;  1JAP A;  3F16 A;  5D2B A;  2W15 A;  4AYK A;  1IAB A;  4AXQ A;  1KUF A;  1Q3A A;  1MMP A;  2FV9 A;  1I73 A;  3G5C A;  4PKR A;  1EAK A;  1OM6 A;  4DPE A;  1R55 A;  966C A;  2XS3 A;  5D1U A;  2SRT A;  1G4K A;  3O64 A;  1CGF A;  1AKL A;  1JAN A;  1YP1 A;  3DTI A;  3KEK A;  4FXY P;  5CUH A;  1YQY A;  5D3C A;  3DTE A;  5JMY A;  3L0T A;  3P24 A;  1R1I A;  3F1A A;  3TT4 A;  2DW1 A;  3NX7 A;  4EFS A;  3E8R A;  4JQG A;  1SU3 A;  1I76 A;  1K7Q A;  1JK3 A;  1YOU A;  1SRP A;  1XUR A;  4H76 A;  3EWJ A;  3VTG A;  5L79 A;  3KMC A;  4DF9 A;  1GKC A;  4H49 A;  3LJT A;  1BIW A;  2O36 A;  4WKE A;  1HV5 A;  1DTH A;  1K7G A;  3DPF A;  2JT6 A;  3KEC A;  3I7G A;  2YUF A;  3HDA P;  2JT5 A;  3L0V A;  1R1J A;  2DDY A;  1HY7 A;  3HBU P;  4A7B A;  1MMR A;  5I2Z A;  4GR0 A;  5D1T A;  1IAE A;  1PWP A;  3SHI A;  5I43 A;  3HB2 P;  2OVZ A;  5D1S A;  2AYK A;  5L7F A;  2OVX A;  4IUW A;  3LK8 A;  1ATL A;  4PKU A;  4XCT A;  1QJJ A;  4XM6 A;  4H3X A;  1JIW P;  1AF0 A;  3LKA A;  5I12 A;  4XM7 A;  1MMQ A;  1ROS A;  3HY9 A;  5B5P A;  2DW0 A;  3AYU A;  2MZE A;  4GF1 A;  1GO7 P;  1D7X A;  3DPE A;  2A8H A;  1A86 A;  3N2V A;  2Z2D A;  1HTD A;  4HX3 A;  3TSK A;  1XFX A;  2OW2 A;  4GUY A;  3Q2H A;  1USN A;  3U1R A;  1CXV A;  1K7I A;  4PKW A;  1GE6 A;  1CK7 A;  1Y93 A;  2J83 A;  1A85 A;  2X3C A;  4AIG A;  1GE5 A;  1XFV A;  4G0D A;  1Z3J A;  2POJ A;  4AUO A;  4L63 A;  1G49 A;  1OO9 A;  3P1V A;  2K9C A;  4XBH A;  1KUI A;  1S4B P;  2OW9 A;  3BA0 A;  3DL1 A;  3WV3 A;  1G12 A;  1CGL A;  1QIA A;  1OMJ A;  3TVC A;  1XFW A;  1JH1 A;  1GE7 A;  2WO9 A;  3LQ0 A;  4H82 A;  1BUD A;  4ZR5 A;  4JP4 A;  3WV1 A;  3DNG A;  1I1I P;  3EDI A;  4J4M A;  3EDH A;  3LEA A;  4GWN A;  4I03 A;  3DWB A;  3KHI A;  2E2D A;  1GXD A;  1HFC A;  4A3W A;  4I35 A;  2YIG A;  2JSD A;  2RJP A;  2D1N A;  2W0D A;  1PWV A;  4PKQ A;  5B5O A;  1PWW A;  1R54 A;  4L6T A;  5I4O A;  456C A;  1IAA A;  1CAQ A;  4WK7 A;  1PWU A;  1ZXC A;  3HBV P;  3AYK A;  4FVL A;  2DDF A;  2CLT A;  4IJO A;  1SMP A;  3LUN A;  2N8R A;  2OXW A;  2PJT A;  4GWM A;  1RMZ A;  4ILW D;  5I0L A;  4GR3 A;  4L19 A;  830C A;  3F19 A;  1XFU A;  3ZVS A;  5CXA A;  1CQR A;  3LIR A;  3KME A;  1ND1 A;  3CKI A;  3LMC A;  1R1H A;  2FV5 A;  3GBO A;  1EB6 A;  5BOY A;  2TCL A;  4JA1 A;  1KUK A;  1BKC A;  3F17 A;  2MLR A;  1UTT A;  2WO8 A;  2L0R A;  2W13 A;  3KRY A;  1BSW A;  3LQB A;  4HMA A;  4JPA A;  1RM8 A;  1B8Y A;  1XFY A;  2X3A A;  2OY2 A;  1XUD A;  3N2U A;  1UMT A;  4ON1 A;  3F15 A;  2D1O A;  2OW0 A;  2HU6 A;  1G05 A;  3HDB A;  1ZTQ A;  1QIC A;  1BUV M;  2JNP A;  2Y6D A;  3KWV C;  3LIL A;  1JJ9 A;  1OM8 A;  5BOT A;  1C7K A;  4JIJ A;  3USN A;  1CGE A;  4L7A A;  2ERO A;  3AIG A;  1IAG A;  4GQL A;  2K2G A;  2I47 A;  1BQQ M;  3ELM A;  2MZI A;  1CIZ A;  1O0Q A;  1XUC A;  1UEA A;  1ZP5 A;  2QPJ A;  1D8M A;  1IAD A;  1OS9 A;  1BQO A;  3V96 B;  3ZUK A;  3RTT A;  3LJG A;  4Q1L A;  3EDG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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