4GQLA

Crystal structure of the catalytic domain of human mmp12 in complex with selective phosphinic inhibitor rxp470.1
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
159
structure length
159
Chain Sequence
MGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular determinants of a selective matrix metalloprotease-12 inhibitor: insights from crystallography and thermodynamic studies.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Macrophage metalloelastase
total genus 41
structure length 159
sequence length 159
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2012-08-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 4gqlA00
1JAQA 1R55A 1XFUA 4DF9A 1RM8A 1XUCA 1ZTQA 2D1OA 2CKIA 2L0RA 2E3XA 4L19A 2JSDA 1YQYA 3DPEA 1ZXVA 3F18A 5I12A 4A3WA 2DDYA 4GQLA 1D8FA 1PWUA 3F1AA 4FU4A 1OM7A 5CUHA 3HBUP 2ERPA 3WV3A 1G12A 2N8RA 3DL1A 1S4BP 2HU6A 1ZXCA 1KUHA 2MLRA 3TT4A 3E8RA 4L6TA 3P1VA 3EWJA 1ZP5A 3OHLA 2Z2DA 3LJTA 3TS4A 1MMRA 1FLSA 3TSKA 4IUWA 4AUOA 2XS3A 1Z3JA 1JAOA 5D2BA 2W12A 4AIGA 5CZMA 4GF1A 2JT5A 4H1QA 3HY7A 3ELMA 966CA 3HBVP 1G49A 2X3BA 1KUKA 4XBHA 2I47A 1J7NA 3LJGA 1OMJA 1AF0A 1SRPA 1A86A 3Q2HA 3B2ZA 1I1IP 3LUMA 4DD8A 1XUDA 2OZRA 2JNPA 5I3MA 4HMAA 1O0TA 1ROSA 1KUFA 2DDFA 3WV1A 1OO9A 2O36A 1QJIA 2CLTA 1SATA 2J0TA 2OVZA 1HFCA 3TVCA 1OM6A 3HY9A 1XFYA 1EUBA 1G9KA 1R1JA 1BM6A 4AXQA 2X3AA 3EDZA 1AKLA 2E2DA 3HDAP 1BQQM 1MMPA 1CIZA 4WF6A 1KUGA 1Y93A 2OW2A 3AYKA 3DSLA 1YCMA 1EAKA 4G9LA 3DWBA 3LMCA 1Q3AA 2DW0A 1BZSA 3KMEA 3I7IA 5I2ZA 3K7LA 3HYGA 1YP1A 2JT6A 2W14A 2WOAA 4XM7A 1R54A 4PKRA 2W0DA 1CAQA 5BPAA 2W15A 4JIJA 1BSWA 1QJJA 1OM8A 1O0QA 2A8HA 2OI0A 3HB2P 1QIAA 2OXUA 830CA 4WK7A 5H8XA 2FV9A 3F15A 3L0VA 3EHYA 5I43A 4WKEA 4PKVA 1DTHA 2SRTA 5BOYA 1GKCA 3RTTA 1ZVXA 3O2XA 3V96B 4I03A 1OS2A 1Y0VA 3K7NA 4H3XA 3LK8A 5D1TA 4GWMA 5D1UA 1K7IA 2DW1A 3F16A 3UVCA 4GWNA 2Y6DA 1H71P 1G05A 3DNGA 2MZIA 1MNCA 1GKDA 4A7BA 3F17A 4DV8A 2X7MA 5LABA 1FM1A 5B5PA 3EHXA 3U1RA 4FXYP 1UTTA 2OW0A 1QICA 1QIBA 3EDIA 2D1NA 3NX7A 4H2EA 1CK7A 3N2VA 2WO8A 1SLNA 3KEKA 4H30A 3L0TA 1UTZA 1IAAA 5JMYA 1I76A 1GO8P 3HDBA 2MZHA 2OVXA 4GR3A 2DW2A 1HTDA 4IN9A 3LIKA 1BKCI 3KHIA 5L7FA 3GBOA 1D8MA 4HX3A 4JPAA 1B8YA 3LQ0A 2MZEA 1GXDA 4ZR5A 3EDHA 4H84A 4GR8A 4AYKA 1B3DA 3RTSA 1PWWA 2YIGA 4EFSA 1CQRA 2K2GA 2YB9A 3F19A 2PJTA 4H49A 1BKCA 2OXWA 2K9CA 3KWVC 4I35A 1XFZA 1XFVA 4FXQA 5B5OA 1PWVA 4GUYA 4L63A 1JKYA 3G5CA 1FBLA 1CGFA 1EB6A 2EROA 1UMSA 1KBCA 1UEAA 4PKTA 2AIGP 1G4KA 3ZXHA 2XS4A 5D7WA 2RJPA 3LILA 1ND1A 4Q1LA 4PKWA 1SMPA 5I4OA 1JANA 1UMTA 1BUDA 1CGLA 3AIGA 1DMTA 1I73A 3LQBA 3ZUKA 1JH1A 1JAPA 4PKSA 1HFSA 2MLSA 4H82A 3WV2A 2ERQA 3KMCA 4FVLA 1D7XA 3DPFA 4GR0A 3KRYA 1QUAA 3N2UA 3I7GA 3KEJA 4CTHA 1SU3A 3MA2A 1C3IA 4JA1A 5I0LA 1YOUA 1K7QA 1GE7A 4H76A 4XM6A 3B92A 3LJZA 4XCTA 2OW1A 1BKCE 1L6JA 4ON1A 4IJOA 1SLMA 4R3VA 1JIWP 1BUVM 1GO7P 2JIHA 1C7KA 4DPEA 1XFWA 4G0DA 2QPJA 1ZS0A 3VI1A 3USNA 4PKQA 1OS9A 1BQOA 3G42A 4QKZA 1XFXA 2TCLA 4WZVA 1HOVA 5D3CA 1IACA 1WNIA 4JP4A 5D1SA 2OY4A 1JIZA 2OXZA 1AYKA 3CKIA 3OHOA 3AYUA 2AYKA 2V4BA 3LUNA 1ASTA 1R1IA 4J4MA 1ATLA 2W13A 2WO9A 1K7GA 3LIRA 1HV5A 5CXAA 1BIWA 2USNA 1D5JA 1IAGA 1C8TA 2FV5A 1PWPA 5BOTA 3LKAA 3B8ZA 1USNA 3LE9A 4XM8A 1MMQA 2POJA 4PKUA 2X3CA 2Y6CA 4WKIA 3ZVSA 1IAEA 5L79A 4JQGA 2J83A 3EDGA 1IABA 1R1HA 1KUIA 3O64A 3BA0A 1GE6A 4ILWD 3VTGA 1MMBA 2OW9A 1JK3A 1CGEA 2RJQA 1XURA 3LEAA 3Q2GA 1GE5A 1JJ9A 2O3EA 1A85A 3LGPA 1IADA 1Y8JA 1KAPP 3P24A 3SHIA 1PWQA 1RMZA 2KRJA 456CA 2OY2A 1HY7A 3KECA 1CXVA
chains in the Genus database with same CATH superfamily
1JAQA 1R55A 1XFUA 4DF9A 1RM8A 1XUCA 1ZTQA 2D1OA 2CKIA 2L0RA 2E3XA 4L19A 2JSDA 1YQYA 3DPEA 1ZXVA 3F18A 5I12A 4A3WA 2DDYA 4GQLA 1D8FA 1PWUA 3F1AA 4FU4A 1OM7A 5CUHA 3HBUP 2ERPA 3WV3A 1G12A 2N8RA 3DL1A 1S4BP 2HU6A 1ZXCA 1KUHA 2MLRA 3TT4A 3E8RA 4L6TA 3P1VA 3EWJA 1ZP5A 3OHLA 2Z2DA 3LJTA 3TS4A 1MMRA 1FLSA 3TSKA 4IUWA 4AUOA 2XS3A 3DTIA 1Z3JA 1JAOA 5D2BA 2W12A 4AIGA 5CZMA 4GF1A 2JT5A 4H1QA 3HY7A 3ELMA 966CA 3HBVP 1G49A 2X3BA 1KUKA 4XBHA 2I47A 1J7NA 3LJGA 1OMJA 1AF0A 1SRPA 1A86A 3Q2HA 3B2ZA 1I1IP 3LUMA 4DD8A 1XUDA 2OZRA 2JNPA 5I3MA 4HMAA 1O0TA 1ROSA 1KUFA 2DDFA 3WV1A 1OO9A 2O36A 1QJIA 2CLTA 1SATA 2J0TA 2OVZA 1HFCA 3TVCA 1OM6A 3HY9A 1XFYA 1EUBA 1G9KA 1R1JA 1BM6A 4AXQA 2X3AA 3EDZA 1AKLA 2E2DA 1TVIA 3HDAP 1XAXA 1BQQM 1MMPA 1CIZA 4WF6A 1KUGA 1Y93A 2OW2A 3AYKA 3DSLA 1YCMA 1EAKA 4G9LA 3DWBA 3LMCA 3DTKA 1Q3AA 2DW0A 1BZSA 3KMEA 3I7IA 5I2ZA 3K7LA 3HYGA 1YP1A 2JT6A 2W14A 2WOAA 4XM7A 1R54A 4PKRA 2W0DA 1CAQA 5BPAA 2W15A 4JIJA 1BSWA 1QJJA 1OM8A 1O0QA 2A8HA 2OI0A 3HB2P 1QIAA 2OXUA 830CA 4WK7A 5H8XA 2FV9A 3F15A 3L0VA 3EHYA 5I43A 4WKEA 4PKVA 1DTHA 2SRTA 5BOYA 1GKCA 1OZ9A 3RTTA 1ZVXA 3O2XA 3V96B 4I03A 1OS2A 1Y0VA 3K7NA 4H3XA 3LK8A 5D1TA 4GWMA 5D1UA 1K7IA 2DW1A 3F16A 3UVCA 4GWNA 2Y6DA 1H71P 1G05A 3DNGA 2MZIA 1MNCA 1GKDA 4A7BA 3F17A 4DV8A 2X7MA 5LABA 1FM1A 5B5PA 3EHXA 3U1RA 4FXYP 1UTTA 2OW0A 1QICA 1QIBA 3EDIA 2D1NA 3NX7A 4H2EA 1CK7A 3N2VA 2WO8A 1SLNA 3KEKA 2YUFA 4H30A 3L0TA 1UTZA 1IAAA 5JMYA 1I76A 1GO8P 3HDBA 2MZHA 2OVXA 4GR3A 2DW2A 1HTDA 4IN9A 3LIKA 1BKCI 3KHIA 5L7FA 3GBOA 1D8MA 4HX3A 4JPAA 1B8YA 3LQ0A 2MZEA 1GXDA 4ZR5A 3EDHA 4H84A 4GR8A 4AYKA 1B3DA 3RTSA 1PWWA 2YIGA 4EFSA 1CQRA 2K2GA 2YB9A 3F19A 2PJTA 4H49A 1BKCA 2OXWA 2K9CA 3KWVC 4I35A 1XFZA 1XFVA 4FXQA 5B5OA 1PWVA 4GUYA 4L63A 1JKYA 3G5CA 1FBLA 1CGFA 1EB6A 2EROA 1UMSA 1KBCA 1UEAA 4PKTA 2AIGP 1G4KA 1XM5A 3ZXHA 2XS4A 5D7WA 2RJPA 3LILA 1ND1A 4Q1LA 4PKWA 1SMPA 5I4OA 1JANA 1UMTA 1BUDA 1CGLA 3AIGA 1DMTA 1I73A 3LQBA 3ZUKA 1JH1A 1JAPA 4PKSA 1HFSA 2MLSA 4H82A 3WV2A 2ERQA 3KMCA 4FVLA 1D7XA 3DPFA 4GR0A 3KRYA 1QUAA 3N2UA 3I7GA 3KEJA 4CTHA 1SU3A 3MA2A 1C3IA 4JA1A 5I0LA 1YOUA 1K7QA 1GE7A 4H76A 4XM6A 3B92A 3LJZA 4XCTA 2OW1A 1BKCE 1L6JA 4ON1A 4IJOA 1SLMA 4R3VA 1JIWP 1BUVM 1GO7P 2JIHA 1C7KA 4DPEA 1XFWA 4G0DA 2QPJA 1ZS0A 3VI1A 3USNA 4PKQA 1OS9A 1BQOA 3G42A 4QKZA 1XFXA 2TCLA 4WZVA 1HOVA 5D3CA 1IACA 1WNIA 4JP4A 5D1SA 2OY4A 1JIZA 2OXZA 1AYKA 3CKIA 3OHOA 3AYUA 2AYKA 2V4BA 3LUNA 1ASTA 1R1IA 4J4MA 1ATLA 2W13A 2WO9A 1K7GA 3LIRA 1HV5A 5CXAA 1BIWA 2USNA 1D5JA 1IAGA 1C8TA 2FV5A 1PWPA 5BOTA 3LKAA 3B8ZA 1USNA 3LE9A 4XM8A 1MMQA 2POJA 4PKUA 2X3CA 2Y6CA 4WKIA 3ZVSA 1IAEA 5L79A 4JQGA 2J83A 3EDGA 1IABA 1R1HA 1KUIA 3O64A 3BA0A 1GE6A 4ILWD 3VTGA 1MMBA 2OW9A 1JK3A 1CGEA 2RJQA 1XURA 3LEAA 3Q2GA 4L7AA 1GE5A 1JJ9A 2O3EA 1A85A 3LGPA 1IADA 1Y8JA 1KAPP 3P24A 3SHIA 1PWQA 1RMZA 2KRJA 456CA 3DTEA 2OY2A 1HY7A 3KECA 1CXVA
chains in the Genus database with same CATH topology
1JAQA 1R55A 1XFUA 4DF9A 1RM8A 1XUCA 1ZTQA 2D1OA 2CKIA 2L0RA 2E3XA 4L19A 2JSDA 1YQYA 3DPEA 1ZXVA 3F18A 5I12A 4A3WA 2DDYA 4GQLA 1D8FA 1PWUA 3F1AA 4FU4A 1OM7A 5CUHA 3HBUP 2ERPA 3WV3A 1G12A 2N8RA 3DL1A 1S4BP 2HU6A 1ZXCA 1KUHA 2MLRA 3TT4A 3E8RA 4L6TA 3P1VA 3EWJA 1ZP5A 3OHLA 2Z2DA 3LJTA 3TS4A 1MMRA 1FLSA 3TSKA 4IUWA 4AUOA 2XS3A 3DTIA 1Z3JA 1JAOA 5D2BA 2W12A 4AIGA 5CZMA 4GF1A 2JT5A 4H1QA 3HY7A 3ELMA 966CA 3HBVP 1G49A 2X3BA 1KUKA 4XBHA 2I47A 1J7NA 3LJGA 1OMJA 1AF0A 1SRPA 1A86A 3Q2HA 3B2ZA 1I1IP 3LUMA 4DD8A 1XUDA 2OZRA 2JNPA 5I3MA 4HMAA 1O0TA 1ROSA 1KUFA 2DDFA 3WV1A 1OO9A 2O36A 1QJIA 2CLTA 1SATA 2J0TA 2OVZA 1HFCA 3TVCA 1OM6A 3HY9A 1XFYA 1EUBA 1G9KA 1R1JA 1BM6A 4AXQA 2X3AA 3EDZA 1AKLA 2E2DA 3HDAP 1BQQM 1MMPA 1CIZA 4WF6A 1KUGA 1Y93A 2OW2A 3AYKA 3DSLA 1YCMA 1EAKA 4G9LA 3DWBA 3LMCA 3DTKA 1Q3AA 2DW0A 1BZSA 3KMEA 3I7IA 5I2ZA 3K7LA 3HYGA 1YP1A 2JT6A 2W14A 2WOAA 4XM7A 1R54A 4PKRA 2W0DA 1CAQA 5BPAA 2W15A 4JIJA 1BSWA 1QJJA 1OM8A 1O0QA 2A8HA 2OI0A 3HB2P 1QIAA 2OXUA 830CA 4WK7A 5H8XA 2FV9A 3F15A 3L0VA 3EHYA 5I43A 4WKEA 4PKVA 1DTHA 2SRTA 5BOYA 1GKCA 3RTTA 1ZVXA 3O2XA 3V96B 4I03A 1OS2A 1Y0VA 3K7NA 4H3XA 3LK8A 5D1TA 4GWMA 5D1UA 1K7IA 2DW1A 3F16A 3UVCA 4GWNA 2Y6DA 1H71P 1G05A 3DNGA 2MZIA 1MNCA 1GKDA 4A7BA 3F17A 4DV8A 2X7MA 5LABA 1FM1A 5B5PA 3EHXA 3U1RA 4FXYP 1UTTA 2OW0A 1QICA 1QIBA 3EDIA 2D1NA 3NX7A 4H2EA 1CK7A 3N2VA 2WO8A 1SLNA 3KEKA 2YUFA 4H30A 3L0TA 1UTZA 1IAAA 5JMYA 1I76A 1GO8P 3HDBA 2MZHA 2OVXA 4GR3A 2DW2A 1HTDA 4IN9A 3LIKA 1BKCI 3KHIA 5L7FA 3GBOA 1D8MA 4HX3A 4JPAA 1B8YA 3LQ0A 2MZEA 1GXDA 4ZR5A 3EDHA 4H84A 4GR8A 4AYKA 1B3DA 3RTSA 1PWWA 2YIGA 4EFSA 1CQRA 2K2GA 2YB9A 3F19A 2PJTA 4H49A 1BKCA 2OXWA 2K9CA 3KWVC 4I35A 1XFZA 1XFVA 4FXQA 5B5OA 1PWVA 4GUYA 4L63A 1JKYA 3G5CA 1FBLA 1CGFA 1EB6A 2EROA 1UMSA 1KBCA 1UEAA 4PKTA 2AIGP 1G4KA 3ZXHA 2XS4A 5D7WA 2RJPA 3LILA 1ND1A 4Q1LA 4PKWA 1SMPA 5I4OA 1JANA 1UMTA 1BUDA 1CGLA 3AIGA 1DMTA 1I73A 3LQBA 3ZUKA 1JH1A 1JAPA 4PKSA 1HFSA 2MLSA 4H82A 3WV2A 2ERQA 3KMCA 4FVLA 1D7XA 3DPFA 4GR0A 3KRYA 1QUAA 3N2UA 3I7GA 3KEJA 4CTHA 1SU3A 3MA2A 1C3IA 4JA1A 5I0LA 1YOUA 1K7QA 1GE7A 4H76A 4XM6A 3B92A 3LJZA 4XCTA 2OW1A 1BKCE 1L6JA 4ON1A 4IJOA 1SLMA 4R3VA 1JIWP 1BUVM 1GO7P 2JIHA 1C7KA 4DPEA 1XFWA 4G0DA 2QPJA 1ZS0A 3VI1A 3USNA 4PKQA 1OS9A 1BQOA 3G42A 4QKZA 1XFXA 2TCLA 4WZVA 1HOVA 5D3CA 1IACA 1WNIA 4JP4A 5D1SA 2OY4A 1JIZA 2OXZA 1AYKA 3CKIA 3OHOA 3AYUA 2AYKA 2V4BA 3LUNA 1ASTA 1R1IA 4J4MA 1ATLA 2W13A 2WO9A 1K7GA 3LIRA 1HV5A 5CXAA 1BIWA 2USNA 1D5JA 1IAGA 1C8TA 2FV5A 1PWPA 5BOTA 3LKAA 3B8ZA 1USNA 3LE9A 4XM8A 1MMQA 2POJA 4PKUA 2X3CA 2Y6CA 4WKIA 3ZVSA 1IAEA 5L79A 4JQGA 2J83A 3EDGA 1IABA 1R1HA 1KUIA 3O64A 3BA0A 1GE6A 4ILWD 3VTGA 1MMBA 2OW9A 1JK3A 1CGEA 2RJQA 1XURA 3LEAA 3Q2GA 4L7AA 1GE5A 1JJ9A 2O3EA 1A85A 3LGPA 1IADA 1Y8JA 1KAPP 3P24A 3SHIA 1PWQA 1RMZA 2KRJA 456CA 3DTEA 2OY2A 1HY7A 3KECA 1CXVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JAQ A;  1R55 A;  1XFU A;  4DF9 A;  1RM8 A;  1XUC A;  1ZTQ A;  2D1O A;  2CKI A;  2L0R A;  2E3X A;  4L19 A;  2JSD A;  1YQY A;  3DPE A;  1ZXV A;  3F18 A;  5I12 A;  4A3W A;  2DDY A;  4GQL A;  1D8F A;  1PWU A;  3F1A A;  4FU4 A;  1OM7 A;  5CUH A;  3HBU P;  2ERP A;  3WV3 A;  1G12 A;  2N8R A;  3DL1 A;  1S4B P;  2HU6 A;  1ZXC A;  1KUH A;  2MLR A;  3TT4 A;  3E8R A;  4L6T A;  3P1V A;  3EWJ A;  1ZP5 A;  3OHL A;  2Z2D A;  3LJT A;  3TS4 A;  1MMR A;  1FLS A;  3TSK A;  4IUW A;  4AUO A;  2XS3 A;  1Z3J A;  1JAO A;  5D2B A;  2W12 A;  4AIG A;  5CZM A;  4GF1 A;  2JT5 A;  4H1Q A;  3HY7 A;  3ELM A;  966C A;  3HBV P;  1G49 A;  2X3B A;  1KUK A;  4XBH A;  2I47 A;  1J7N A;  3LJG A;  1OMJ A;  1AF0 A;  1SRP A;  1A86 A;  3Q2H A;  3B2Z A;  1I1I P;  3LUM A;  4DD8 A;  1XUD A;  2OZR A;  2JNP A;  5I3M A;  4HMA A;  1O0T A;  1ROS A;  1KUF A;  2DDF A;  3WV1 A;  1OO9 A;  2O36 A;  1QJI A;  2CLT A;  1SAT A;  2J0T A;  2OVZ A;  1HFC A;  3TVC A;  1OM6 A;  3HY9 A;  1XFY A;  1EUB A;  1G9K A;  1R1J A;  1BM6 A;  4AXQ A;  2X3A A;  3EDZ A;  1AKL A;  2E2D A;  3HDA P;  1BQQ M;  1MMP A;  1CIZ A;  4WF6 A;  1KUG A;  1Y93 A;  2OW2 A;  3AYK A;  3DSL A;  1YCM A;  1EAK A;  4G9L A;  3DWB A;  3LMC A;  1Q3A A;  2DW0 A;  1BZS A;  3KME A;  3I7I A;  5I2Z A;  3K7L A;  3HYG A;  1YP1 A;  2JT6 A;  2W14 A;  2WOA A;  4XM7 A;  1R54 A;  4PKR A;  2W0D A;  1CAQ A;  5BPA A;  2W15 A;  4JIJ A;  1BSW A;  1QJJ A;  1OM8 A;  1O0Q A;  2A8H A;  2OI0 A;  3HB2 P;  1QIA A;  2OXU A;  830C A;  4WK7 A;  5H8X A;  2FV9 A;  3F15 A;  3L0V A;  3EHY A;  5I43 A;  4WKE A;  4PKV A;  1DTH A;  2SRT A;  5BOY A;  1GKC A;  3RTT A;  1ZVX A;  3O2X A;  3V96 B;  4I03 A;  1OS2 A;  1Y0V A;  3K7N A;  4H3X A;  3LK8 A;  5D1T A;  4GWM A;  5D1U A;  1K7I A;  2DW1 A;  3F16 A;  3UVC A;  4GWN A;  2Y6D A;  1H71 P;  1G05 A;  3DNG A;  2MZI A;  1MNC A;  1GKD A;  4A7B A;  3F17 A;  4DV8 A;  2X7M A;  5LAB A;  1FM1 A;  5B5P A;  3EHX A;  3U1R A;  4FXY P;  1UTT A;  2OW0 A;  1QIC A;  1QIB A;  3EDI A;  2D1N A;  3NX7 A;  4H2E A;  1CK7 A;  3N2V A;  2WO8 A;  1SLN A;  3KEK A;  4H30 A;  3L0T A;  1UTZ A;  1IAA A;  5JMY A;  1I76 A;  1GO8 P;  3HDB A;  2MZH A;  2OVX A;  4GR3 A;  2DW2 A;  1HTD A;  4IN9 A;  3LIK A;  1BKC I;  3KHI A;  5L7F A;  3GBO A;  1D8M A;  4HX3 A;  4JPA A;  1B8Y A;  3LQ0 A;  2MZE A;  1GXD A;  4ZR5 A;  3EDH A;  4H84 A;  4GR8 A;  4AYK A;  1B3D A;  3RTS A;  1PWW A;  2YIG A;  4EFS A;  1CQR A;  2K2G A;  2YB9 A;  3F19 A;  2PJT A;  4H49 A;  1BKC A;  2OXW A;  2K9C A;  3KWV C;  4I35 A;  1XFZ A;  1XFV A;  4FXQ A;  5B5O A;  1PWV A;  4GUY A;  4L63 A;  1JKY A;  3G5C A;  1FBL A;  1CGF A;  1EB6 A;  2ERO A;  1UMS A;  1KBC A;  1UEA A;  4PKT A;  2AIG P;  1G4K A;  3ZXH A;  2XS4 A;  5D7W A;  2RJP A;  3LIL A;  1ND1 A;  4Q1L A;  4PKW A;  1SMP A;  5I4O A;  1JAN A;  1UMT A;  1BUD A;  1CGL A;  3AIG A;  1DMT A;  1I73 A;  3LQB A;  3ZUK A;  1JH1 A;  1JAP A;  4PKS A;  1HFS A;  2MLS A;  4H82 A;  3WV2 A;  2ERQ A;  3KMC A;  4FVL A;  1D7X A;  3DPF A;  4GR0 A;  3KRY A;  1QUA A;  3N2U A;  3I7G A;  3KEJ A;  4CTH A;  1SU3 A;  3MA2 A;  1C3I A;  4JA1 A;  5I0L A;  1YOU A;  1K7Q A;  1GE7 A;  4H76 A;  4XM6 A;  3B92 A;  3LJZ A;  4XCT A;  2OW1 A;  1BKC E;  1L6J A;  4ON1 A;  4IJO A;  1SLM A;  4R3V A;  1JIW P;  1BUV M;  1GO7 P;  2JIH A;  1C7K A;  4DPE A;  1XFW A;  4G0D A;  2QPJ A;  1ZS0 A;  3VI1 A;  3USN A;  4PKQ A;  1OS9 A;  1BQO A;  3G42 A;  4QKZ A;  1XFX A;  2TCL A;  4WZV A;  1HOV A;  5D3C A;  1IAC A;  1WNI A;  4JP4 A;  5D1S A;  2OY4 A;  1JIZ A;  2OXZ A;  1AYK A;  3CKI A;  3OHO A;  3AYU A;  2AYK A;  2V4B A;  3LUN A;  1AST A;  1R1I A;  4J4M A;  1ATL A;  2W13 A;  2WO9 A;  1K7G A;  3LIR A;  1HV5 A;  5CXA A;  1BIW A;  2USN A;  1D5J A;  1IAG A;  1C8T A;  2FV5 A;  1PWP A;  5BOT A;  3LKA A;  3B8Z A;  1USN A;  3LE9 A;  4XM8 A;  1MMQ A;  2POJ A;  4PKU A;  2X3C A;  2Y6C A;  4WKI A;  3ZVS A;  1IAE A;  5L79 A;  4JQG A;  2J83 A;  3EDG A;  1IAB A;  1R1H A;  1KUI A;  3O64 A;  3BA0 A;  1GE6 A;  4ILW D;  3VTG A;  1MMB A;  2OW9 A;  1JK3 A;  1CGE A;  2RJQ A;  1XUR A;  3LEA A;  3Q2G A;  1GE5 A;  1JJ9 A;  2O3E A;  1A85 A;  3LGP A;  1IAD A;  1Y8J A;  1KAP P;  3P24 A;  3SHI A;  1PWQ A;  1RMZ A;  2KRJ A;  456C A;  2OY2 A;  1HY7 A;  3KEC A;  1CXV A; 
#chains in the Genus database with same CATH topology
 1JAQ A;  1R55 A;  1XFU A;  4DF9 A;  1RM8 A;  1XUC A;  1ZTQ A;  2D1O A;  2CKI A;  2L0R A;  2E3X A;  4L19 A;  2JSD A;  1YQY A;  3DPE A;  1ZXV A;  3F18 A;  5I12 A;  4A3W A;  2DDY A;  4GQL A;  1D8F A;  1PWU A;  3F1A A;  4FU4 A;  1OM7 A;  5CUH A;  3HBU P;  2ERP A;  3WV3 A;  1G12 A;  2N8R A;  3DL1 A;  1S4B P;  2HU6 A;  1ZXC A;  1KUH A;  2MLR A;  3TT4 A;  3E8R A;  4L6T A;  3P1V A;  3EWJ A;  1ZP5 A;  3OHL A;  2Z2D A;  3LJT A;  3TS4 A;  1MMR A;  1FLS A;  3TSK A;  4IUW A;  4AUO A;  2XS3 A;  3DTI A;  1Z3J A;  1JAO A;  5D2B A;  2W12 A;  4AIG A;  5CZM A;  4GF1 A;  2JT5 A;  4H1Q A;  3HY7 A;  3ELM A;  966C A;  3HBV P;  1G49 A;  2X3B A;  1KUK A;  4XBH A;  2I47 A;  1J7N A;  3LJG A;  1OMJ A;  1AF0 A;  1SRP A;  1A86 A;  3Q2H A;  3B2Z A;  1I1I P;  3LUM A;  4DD8 A;  1XUD A;  2OZR A;  2JNP A;  5I3M A;  4HMA A;  1O0T A;  1ROS A;  1KUF A;  2DDF A;  3WV1 A;  1OO9 A;  2O36 A;  1QJI A;  2CLT A;  1SAT A;  2J0T A;  2OVZ A;  1HFC A;  3TVC A;  1OM6 A;  3HY9 A;  1XFY A;  1EUB A;  1G9K A;  1R1J A;  1BM6 A;  4AXQ A;  2X3A A;  3EDZ A;  1AKL A;  2E2D A;  1TVI A;  3HDA P;  1XAX A;  1BQQ M;  1MMP A;  1CIZ A;  4WF6 A;  1KUG A;  1Y93 A;  2OW2 A;  3AYK A;  3DSL A;  1YCM A;  1EAK A;  4G9L A;  3DWB A;  3LMC A;  3DTK A;  1Q3A A;  2DW0 A;  1BZS A;  3KME A;  3I7I A;  5I2Z A;  3K7L A;  3HYG A;  1YP1 A;  2JT6 A;  2W14 A;  2WOA A;  4XM7 A;  1R54 A;  4PKR A;  2W0D A;  1CAQ A;  5BPA A;  2W15 A;  4JIJ A;  1BSW A;  1QJJ A;  1OM8 A;  1O0Q A;  2A8H A;  2OI0 A;  3HB2 P;  1QIA A;  2OXU A;  830C A;  4WK7 A;  5H8X A;  2FV9 A;  3F15 A;  3L0V A;  3EHY A;  5I43 A;  4WKE A;  4PKV A;  1DTH A;  2SRT A;  5BOY A;  1GKC A;  1OZ9 A;  3RTT A;  1ZVX A;  3O2X A;  3V96 B;  4I03 A;  1OS2 A;  1Y0V A;  3K7N A;  4H3X A;  3LK8 A;  5D1T A;  4GWM A;  5D1U A;  1K7I A;  2DW1 A;  3F16 A;  3UVC A;  4GWN A;  2Y6D A;  1H71 P;  1G05 A;  3DNG A;  2MZI A;  1MNC A;  1GKD A;  4A7B A;  3F17 A;  4DV8 A;  2X7M A;  5LAB A;  1FM1 A;  5B5P A;  3EHX A;  3U1R A;  4FXY P;  1UTT A;  2OW0 A;  1QIC A;  1QIB A;  3EDI A;  2D1N A;  3NX7 A;  4H2E A;  1CK7 A;  3N2V A;  2WO8 A;  1SLN A;  3KEK A;  2YUF A;  4H30 A;  3L0T A;  1UTZ A;  1IAA A;  5JMY A;  1I76 A;  1GO8 P;  3HDB A;  2MZH A;  2OVX A;  4GR3 A;  2DW2 A;  1HTD A;  4IN9 A;  3LIK A;  1BKC I;  3KHI A;  5L7F A;  3GBO A;  1D8M A;  4HX3 A;  4JPA A;  1B8Y A;  3LQ0 A;  2MZE A;  1GXD A;  4ZR5 A;  3EDH A;  4H84 A;  4GR8 A;  4AYK A;  1B3D A;  3RTS A;  1PWW A;  2YIG A;  4EFS A;  1CQR A;  2K2G A;  2YB9 A;  3F19 A;  2PJT A;  4H49 A;  1BKC A;  2OXW A;  2K9C A;  3KWV C;  4I35 A;  1XFZ A;  1XFV A;  4FXQ A;  5B5O A;  1PWV A;  4GUY A;  4L63 A;  1JKY A;  3G5C A;  1FBL A;  1CGF A;  1EB6 A;  2ERO A;  1UMS A;  1KBC A;  1UEA A;  4PKT A;  2AIG P;  1G4K A;  1XM5 A;  3ZXH A;  2XS4 A;  5D7W A;  2RJP A;  3LIL A;  1ND1 A;  4Q1L A;  4PKW A;  1SMP A;  5I4O A;  1JAN A;  1UMT A;  1BUD A;  1CGL A;  3AIG A;  1DMT A;  1I73 A;  3LQB A;  3ZUK A;  1JH1 A;  1JAP A;  4PKS A;  1HFS A;  2MLS A;  4H82 A;  3WV2 A;  2ERQ A;  3KMC A;  4FVL A;  1D7X A;  3DPF A;  4GR0 A;  3KRY A;  1QUA A;  3N2U A;  3I7G A;  3KEJ A;  4CTH A;  1SU3 A;  3MA2 A;  1C3I A;  4JA1 A;  5I0L A;  1YOU A;  1K7Q A;  1GE7 A;  4H76 A;  4XM6 A;  3B92 A;  3LJZ A;  4XCT A;  2OW1 A;  1BKC E;  1L6J A;  4ON1 A;  4IJO A;  1SLM A;  4R3V A;  1JIW P;  1BUV M;  1GO7 P;  2JIH A;  1C7K A;  4DPE A;  1XFW A;  4G0D A;  2QPJ A;  1ZS0 A;  3VI1 A;  3USN A;  4PKQ A;  1OS9 A;  1BQO A;  3G42 A;  4QKZ A;  1XFX A;  2TCL A;  4WZV A;  1HOV A;  5D3C A;  1IAC A;  1WNI A;  4JP4 A;  5D1S A;  2OY4 A;  1JIZ A;  2OXZ A;  1AYK A;  3CKI A;  3OHO A;  3AYU A;  2AYK A;  2V4B A;  3LUN A;  1AST A;  1R1I A;  4J4M A;  1ATL A;  2W13 A;  2WO9 A;  1K7G A;  3LIR A;  1HV5 A;  5CXA A;  1BIW A;  2USN A;  1D5J A;  1IAG A;  1C8T A;  2FV5 A;  1PWP A;  5BOT A;  3LKA A;  3B8Z A;  1USN A;  3LE9 A;  4XM8 A;  1MMQ A;  2POJ A;  4PKU A;  2X3C A;  2Y6C A;  4WKI A;  3ZVS A;  1IAE A;  5L79 A;  4JQG A;  2J83 A;  3EDG A;  1IAB A;  1R1H A;  1KUI A;  3O64 A;  3BA0 A;  1GE6 A;  4ILW D;  3VTG A;  1MMB A;  2OW9 A;  1JK3 A;  1CGE A;  2RJQ A;  1XUR A;  3LEA A;  3Q2G A;  4L7A A;  1GE5 A;  1JJ9 A;  2O3E A;  1A85 A;  3LGP A;  1IAD A;  1Y8J A;  1KAP P;  3P24 A;  3SHI A;  1PWQ A;  1RMZ A;  2KRJ A;  456C A;  3DTE A;  2OY2 A;  1HY7 A;  3KEC A;  1CXV A; 
#chains in the Genus database with same CATH homology
 1JAQ A;  1R55 A;  1XFU A;  4DF9 A;  1RM8 A;  1XUC A;  1ZTQ A;  2D1O A;  2CKI A;  2L0R A;  2E3X A;  4L19 A;  2JSD A;  1YQY A;  3DPE A;  1ZXV A;  3F18 A;  5I12 A;  4A3W A;  2DDY A;  4GQL A;  1D8F A;  1PWU A;  3F1A A;  4FU4 A;  1OM7 A;  5CUH A;  3HBU P;  2ERP A;  3WV3 A;  1G12 A;  2N8R A;  3DL1 A;  1S4B P;  2HU6 A;  1ZXC A;  1KUH A;  2MLR A;  3TT4 A;  3E8R A;  4L6T A;  3P1V A;  3EWJ A;  1ZP5 A;  3OHL A;  2Z2D A;  3LJT A;  3TS4 A;  1MMR A;  1FLS A;  3TSK A;  4IUW A;  4AUO A;  2XS3 A;  3DTI A;  1Z3J A;  1JAO A;  5D2B A;  2W12 A;  4AIG A;  5CZM A;  4GF1 A;  2JT5 A;  4H1Q A;  3HY7 A;  3ELM A;  966C A;  3HBV P;  1G49 A;  2X3B A;  1KUK A;  4XBH A;  2I47 A;  1J7N A;  3LJG A;  1OMJ A;  1AF0 A;  1SRP A;  1A86 A;  3Q2H A;  3B2Z A;  1I1I P;  3LUM A;  4DD8 A;  1XUD A;  2OZR A;  2JNP A;  5I3M A;  4HMA A;  1O0T A;  1ROS A;  1KUF A;  2DDF A;  3WV1 A;  1OO9 A;  2O36 A;  1QJI A;  2CLT A;  1SAT A;  2J0T A;  2OVZ A;  1HFC A;  3TVC A;  1OM6 A;  3HY9 A;  1XFY A;  1EUB A;  1G9K A;  1R1J A;  1BM6 A;  4AXQ A;  2X3A A;  3EDZ A;  1AKL A;  2E2D A;  3HDA P;  1BQQ M;  1MMP A;  1CIZ A;  4WF6 A;  1KUG A;  1Y93 A;  2OW2 A;  3AYK A;  3DSL A;  1YCM A;  1EAK A;  4G9L A;  3DWB A;  3LMC A;  3DTK A;  1Q3A A;  2DW0 A;  1BZS A;  3KME A;  3I7I A;  5I2Z A;  3K7L A;  3HYG A;  1YP1 A;  2JT6 A;  2W14 A;  2WOA A;  4XM7 A;  1R54 A;  4PKR A;  2W0D A;  1CAQ A;  5BPA A;  2W15 A;  4JIJ A;  1BSW A;  1QJJ A;  1OM8 A;  1O0Q A;  2A8H A;  2OI0 A;  3HB2 P;  1QIA A;  2OXU A;  830C A;  4WK7 A;  5H8X A;  2FV9 A;  3F15 A;  3L0V A;  3EHY A;  5I43 A;  4WKE A;  4PKV A;  1DTH A;  2SRT A;  5BOY A;  1GKC A;  3RTT A;  1ZVX A;  3O2X A;  3V96 B;  4I03 A;  1OS2 A;  1Y0V A;  3K7N A;  4H3X A;  3LK8 A;  5D1T A;  4GWM A;  5D1U A;  1K7I A;  2DW1 A;  3F16 A;  3UVC A;  4GWN A;  2Y6D A;  1H71 P;  1G05 A;  3DNG A;  2MZI A;  1MNC A;  1GKD A;  4A7B A;  3F17 A;  4DV8 A;  2X7M A;  5LAB A;  1FM1 A;  5B5P A;  3EHX A;  3U1R A;  4FXY P;  1UTT A;  2OW0 A;  1QIC A;  1QIB A;  3EDI A;  2D1N A;  3NX7 A;  4H2E A;  1CK7 A;  3N2V A;  2WO8 A;  1SLN A;  3KEK A;  2YUF A;  4H30 A;  3L0T A;  1UTZ A;  1IAA A;  5JMY A;  1I76 A;  1GO8 P;  3HDB A;  2MZH A;  2OVX A;  4GR3 A;  2DW2 A;  1HTD A;  4IN9 A;  3LIK A;  1BKC I;  3KHI A;  5L7F A;  3GBO A;  1D8M A;  4HX3 A;  4JPA A;  1B8Y A;  3LQ0 A;  2MZE A;  1GXD A;  4ZR5 A;  3EDH A;  4H84 A;  4GR8 A;  4AYK A;  1B3D A;  3RTS A;  1PWW A;  2YIG A;  4EFS A;  1CQR A;  2K2G A;  2YB9 A;  3F19 A;  2PJT A;  4H49 A;  1BKC A;  2OXW A;  2K9C A;  3KWV C;  4I35 A;  1XFZ A;  1XFV A;  4FXQ A;  5B5O A;  1PWV A;  4GUY A;  4L63 A;  1JKY A;  3G5C A;  1FBL A;  1CGF A;  1EB6 A;  2ERO A;  1UMS A;  1KBC A;  1UEA A;  4PKT A;  2AIG P;  1G4K A;  3ZXH A;  2XS4 A;  5D7W A;  2RJP A;  3LIL A;  1ND1 A;  4Q1L A;  4PKW A;  1SMP A;  5I4O A;  1JAN A;  1UMT A;  1BUD A;  1CGL A;  3AIG A;  1DMT A;  1I73 A;  3LQB A;  3ZUK A;  1JH1 A;  1JAP A;  4PKS A;  1HFS A;  2MLS A;  4H82 A;  3WV2 A;  2ERQ A;  3KMC A;  4FVL A;  1D7X A;  3DPF A;  4GR0 A;  3KRY A;  1QUA A;  3N2U A;  3I7G A;  3KEJ A;  4CTH A;  1SU3 A;  3MA2 A;  1C3I A;  4JA1 A;  5I0L A;  1YOU A;  1K7Q A;  1GE7 A;  4H76 A;  4XM6 A;  3B92 A;  3LJZ A;  4XCT A;  2OW1 A;  1BKC E;  1L6J A;  4ON1 A;  4IJO A;  1SLM A;  4R3V A;  1JIW P;  1BUV M;  1GO7 P;  2JIH A;  1C7K A;  4DPE A;  1XFW A;  4G0D A;  2QPJ A;  1ZS0 A;  3VI1 A;  3USN A;  4PKQ A;  1OS9 A;  1BQO A;  3G42 A;  4QKZ A;  1XFX A;  2TCL A;  4WZV A;  1HOV A;  5D3C A;  1IAC A;  1WNI A;  4JP4 A;  5D1S A;  2OY4 A;  1JIZ A;  2OXZ A;  1AYK A;  3CKI A;  3OHO A;  3AYU A;  2AYK A;  2V4B A;  3LUN A;  1AST A;  1R1I A;  4J4M A;  1ATL A;  2W13 A;  2WO9 A;  1K7G A;  3LIR A;  1HV5 A;  5CXA A;  1BIW A;  2USN A;  1D5J A;  1IAG A;  1C8T A;  2FV5 A;  1PWP A;  5BOT A;  3LKA A;  3B8Z A;  1USN A;  3LE9 A;  4XM8 A;  1MMQ A;  2POJ A;  4PKU A;  2X3C A;  2Y6C A;  4WKI A;  3ZVS A;  1IAE A;  5L79 A;  4JQG A;  2J83 A;  3EDG A;  1IAB A;  1R1H A;  1KUI A;  3O64 A;  3BA0 A;  1GE6 A;  4ILW D;  3VTG A;  1MMB A;  2OW9 A;  1JK3 A;  1CGE A;  2RJQ A;  1XUR A;  3LEA A;  3Q2G A;  4L7A A;  1GE5 A;  1JJ9 A;  2O3E A;  1A85 A;  3LGP A;  1IAD A;  1Y8J A;  1KAP P;  3P24 A;  3SHI A;  1PWQ A;  1RMZ A;  2KRJ A;  456C A;  3DTE A;  2OY2 A;  1HY7 A;  3KEC A;  1CXV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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