4HMAA

Crystal structure of an mmp twin carboxylate based inhibitor lc20 in complex with the mmp-9 catalytic domain
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
160
structure length
160
Chain Sequence
FEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGQGYSLFLVAAHQFGHALGLDHSSVPEALMYPMYRFTEGPPLHKDDVNGIRHLYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallization of bi-functional ligand protein complexes.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Matrix metalloproteinase-9
total genus 41
structure length 160
sequence length 160
chains with identical sequence B
ec nomenclature ec 3.4.24.35: Gelatinase B.
pdb deposition date 2012-10-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 4hmaA00
1R54A 4L19A 1C7KA 4HX3A 3HBUP 3DWBA 3LUNA 3F1AA 1FM1A 4WF6A 2USNA 1JAOA 3MA2A 1PWUA 5L79A 1HOVA 1IABA 3U1RA 1CGFA 1RM8A 1JJ9A 1G05A 1K7GA 1SU3A 1PWPA 4G0DA 3KECA 1UMSA 1YOUA 5D1SA 4I35A 1SRPA 4H1QA 4FU4A 4FXYP 3LKAA 1QICA 1UTTA 3F16A 3LILA 3OHLA 2W13A 2XS4A 3L0VA 3HBVP 3N2UA 3V96B 2OW0A 1UMTA 1XFYA 1DTHA 2DDFA 1OM7A 456CA 1C8TA 4H3XA 4PKQA 5JMYA 5H8XA 4ZR5A 3HYGA 1RMZA 1PWQA 1GE6A 1S4BP 3LUMA 5BOYA 3GBOA 1JH1A 1EUBA 1O0TA 3RTSA 2YIGA 1R55A 3EDIA 1SATA 4AIGA 4CTHA 1OO9A 1IADA 4XM7A 1IAEA 3HY9A 5I2ZA 2SRTA 1XUDA 3LQ0A 2TCLA 2X3BA 1G4KA 2A8HA 5B5PA 1GKDA 5BOTA 4WZVA 1IACA 4PKTA 1XFVA 3F17A 3DNGA 3AYKA 3HDBA 5I12A 2CLTA 4R3VA 1GXDA 2FV9A 3UVCA 1KUHA 1XURA 2W12A 3TVCA 5I0LA 2JSDA 4IUWA 2OY2A 2DDYA 1GO7P 4GR8A 4GWMA 3F18A 1HY7A 1H71P 3O64A 2OVZA 2RJPA 4JP4A 1BUVM 2X3CA 2OW1A 3KWVC 1MMRA 1IAGA 3EHXA 2D1OA 1I76A 1CK7A 5D3CA 3EDZA 1BSWA 1QJJA 1YQYA 2WO9A 1BUDA 4AYKA 4XBHA 1JIWP 2JT6A 1KUKA 2I47A 2XS3A 3LJGA 3TT4A 4GF1A 4DD8A 1CGEA 4I03A 1K7QA 3O2XA 2OI0A 1L6JA 3VI1A 1KUFA 3KEJA 4GWNA 4ILWD 4PKRA 4JA1A 1UTZA 1HFSA 1R1JA 1KUIA 2JNPA 2QPJA 4H49A 1ASTA 3EHYA 3LJTA 1GE7A 1KBCA 3LK8A 1I73A 1K7IA 1OM6A 3HY7A 2MLSA 2MZIA 2O36A 1BKCE 4XCTA 1KAPP 1XFZA 5D1TA 1I1IP 1HFCA 1JAQA 2OW9A 1EB6A 1Y93A 2L0RA 2JIHA 5CZMA 3ZUKA 3LE9A 2AIGP 4JPAA 1QJIA 2DW2A 1R1HA 2W0DA 2Z2DA 2K2GA 5I4OA 3B8ZA 2J83A 3Q2HA 3WV2A 5I3MA 1ZXVA 1FBLA 2OW2A 1XFXA 1ROSA 3KEKA 4IN9A 3G42A 2N8RA 3L0TA 2DW0A 3LIRA 3LMCA 2JT5A 1MMBA 1EAKA 2WOAA 3AYUA 5CUHA 1BIWA 2E2DA 3F15A 966CA 4IJOA 1BQOA 1ND1A 1B8YA 3LIKA 3P1VA 2AYKA 1SLMA 3ZXHA 1MMPA 1ATLA 4H30A 1CGLA 2OZRA 2ERQA 3TSKA 5BPAA 4H82A 3N2VA 1DMTA 4H2EA 3CKIA 4XM6A 3WV1A 3BA0A 4HMAA 830CA 1PWWA 1AF0A 3E8RA 4PKWA 2ERPA 2MZHA 1G9KA 3EWJA 5I43A 2J0TA 3KHIA 3AIGA 5D2BA 1GO8P 4JQGA 4A7BA 1B3DA 3G5CA 4PKSA 1SLNA 1OM8A 1GKCA 1JKYA 3HDAP 1D8MA 2KRJA 1JIZA 2FV5A 4ON1A 1YCMA 2D1NA 1D5JA 1XFWA 3EDHA 4DV8A 1ZVXA 2X3AA 2MZEA 1KUGA 1Z3JA 4GUYA 3RTTA 2OY4A 2Y6CA 4J4MA 1JANA 1IAAA 1OS2A 3DSLA 3LGPA 1Y8JA 1C3IA 2CKIA 1G12A 1QUAA 3K7NA 3B92A 5D1UA 1ZTQA 4XM8A 3DPEA 5CXAA 1A85A 3Q2GA 4PKVA 3KRYA 2W14A 4GQLA 4WKIA 3LQBA 3I7IA 1Y0VA 2V4BA 4DF9A 1ZXCA 1JAPA 1MMQA 3DL1A 3USNA 2HU6A 1OMJA 2OVXA 3HB2P 4AXQA 2POJA 1BQQM 1SMPA 1ZP5A 2O3EA 3K7LA 3VTGA 2PJTA 1R1IA 2OXZA 1HV5A 1QIAA 1OS9A 2K9CA 2OXWA 4AUOA 1BM6A 2W15A 4FVLA 4L63A 4DPEA 1CQRA 4GR0A 1MNCA 3I7GA 5D7WA 1CXVA 4QKZA 3TS4A 1XFUA 3DPFA 4WK7A 3EDGA 1J7NA 4H76A 2YB9A 2MLRA 2DW1A 1A86A 1AKLA 1XUCA 1BKCA 4FXQA 1YP1A 3SHIA 3KMCA 3LEAA 3ELMA 4EFSA 2E3XA 4WKEA 4Q1LA 1QIBA 1BKCI 3B2ZA 3WV3A 1D8FA 3NX7A 4JIJA 1USNA 4PKUA 5B5OA 4A3WA 1G49A 2OXUA 1ZS0A 5LABA 1CIZA 1Q3AA 3P24A 5L7FA 3ZVSA 1AYKA 1D7XA 4H84A 2EROA 1CAQA 1PWVA 2Y6DA 4G9LA 1WNIA 2RJQA 1UEAA 4GR3A 3F19A 3LJZA 1O0QA 2WO8A 4L6TA 3KMEA 1BZSA 1JK3A 2X7MA 1HTDA 1GE5A 3OHOA 1FLSA
chains in the Genus database with same CATH superfamily
1R54A 4L19A 1C7KA 4HX3A 3HBUP 3DWBA 3LUNA 3F1AA 1FM1A 4WF6A 2USNA 1JAOA 3MA2A 1PWUA 5L79A 1HOVA 1IABA 3U1RA 1CGFA 1RM8A 1JJ9A 1G05A 1K7GA 1SU3A 1PWPA 4G0DA 3KECA 1UMSA 1YOUA 5D1SA 4I35A 1SRPA 4H1QA 4FU4A 4FXYP 3DTIA 3LKAA 1QICA 1UTTA 3F16A 3LILA 3OHLA 2W13A 2XS4A 3L0VA 3HBVP 3N2UA 3V96B 2OW0A 1UMTA 1XFYA 1DTHA 2DDFA 1OM7A 456CA 1C8TA 4H3XA 4PKQA 5JMYA 5H8XA 4ZR5A 3HYGA 2YUFA 1RMZA 1PWQA 1GE6A 1S4BP 3LUMA 5BOYA 3GBOA 1JH1A 1EUBA 1O0TA 3RTSA 2YIGA 1R55A 3EDIA 1SATA 4AIGA 4CTHA 1OO9A 1IADA 4XM7A 1IAEA 3HY9A 5I2ZA 2SRTA 1XUDA 3LQ0A 2TCLA 2X3BA 1G4KA 2A8HA 5B5PA 1GKDA 5BOTA 4WZVA 1IACA 4PKTA 1XFVA 3F17A 3DNGA 3AYKA 3HDBA 5I12A 2CLTA 4R3VA 1GXDA 2FV9A 3UVCA 1KUHA 1XURA 2W12A 3TVCA 5I0LA 2JSDA 4IUWA 2OY2A 2DDYA 1GO7P 4GR8A 4GWMA 3F18A 1HY7A 1H71P 3O64A 2OVZA 2RJPA 4JP4A 1BUVM 2X3CA 2OW1A 3KWVC 1MMRA 1IAGA 3EHXA 2D1OA 1I76A 1CK7A 5D3CA 3EDZA 1BSWA 1QJJA 1YQYA 2WO9A 1BUDA 4AYKA 4XBHA 1JIWP 2JT6A 1KUKA 2I47A 2XS3A 3LJGA 3TT4A 4GF1A 4DD8A 1CGEA 4I03A 1K7QA 3O2XA 2OI0A 1L6JA 3VI1A 1KUFA 3KEJA 4GWNA 4ILWD 4PKRA 4JA1A 1UTZA 1HFSA 1R1JA 1KUIA 2JNPA 2QPJA 4H49A 1ASTA 3EHYA 3LJTA 1GE7A 1KBCA 3LK8A 1I73A 1K7IA 1OM6A 3HY7A 2MLSA 2MZIA 2O36A 1BKCE 4XCTA 1KAPP 1XFZA 5D1TA 1I1IP 1HFCA 1JAQA 2OW9A 1EB6A 1Y93A 2L0RA 2JIHA 5CZMA 3ZUKA 3LE9A 2AIGP 4JPAA 1QJIA 2DW2A 1R1HA 2W0DA 2Z2DA 2K2GA 5I4OA 3B8ZA 2J83A 3Q2HA 3WV2A 5I3MA 1ZXVA 1FBLA 2OW2A 1XFXA 1ROSA 3KEKA 1XM5A 4IN9A 3G42A 2N8RA 3L0TA 2DW0A 3LIRA 3LMCA 2JT5A 1MMBA 1EAKA 2WOAA 3AYUA 5CUHA 1BIWA 2E2DA 3F15A 966CA 4IJOA 3DTKA 1BQOA 1ND1A 1B8YA 3LIKA 3P1VA 2AYKA 1SLMA 3ZXHA 1MMPA 1ATLA 4H30A 1CGLA 2OZRA 2ERQA 3TSKA 5BPAA 4H82A 3N2VA 1DMTA 4H2EA 3CKIA 4XM6A 3WV1A 3BA0A 4HMAA 830CA 1PWWA 1AF0A 3E8RA 4PKWA 2ERPA 2MZHA 1G9KA 3EWJA 5I43A 2J0TA 3KHIA 3AIGA 5D2BA 1GO8P 4JQGA 4A7BA 1B3DA 3G5CA 4PKSA 1TVIA 1SLNA 1OM8A 1GKCA 1JKYA 3HDAP 1D8MA 2KRJA 1JIZA 2FV5A 4ON1A 1YCMA 2D1NA 1D5JA 1XFWA 3EDHA 4DV8A 1ZVXA 2X3AA 2MZEA 1KUGA 1Z3JA 4GUYA 3RTTA 2OY4A 2Y6CA 4J4MA 1JANA 1IAAA 1OS2A 3DSLA 3LGPA 1Y8JA 1XAXA 1C3IA 2CKIA 1G12A 1QUAA 3K7NA 3B92A 5D1UA 1ZTQA 4XM8A 3DPEA 4L7AA 5CXAA 1A85A 3Q2GA 4PKVA 3KRYA 2W14A 4GQLA 4WKIA 3LQBA 3I7IA 1Y0VA 2V4BA 4DF9A 1ZXCA 1JAPA 1MMQA 3DL1A 3USNA 2HU6A 1OMJA 2OVXA 3HB2P 4AXQA 2POJA 1BQQM 1SMPA 1ZP5A 2O3EA 3K7LA 3VTGA 2PJTA 1R1IA 2OXZA 1HV5A 1QIAA 1OS9A 2K9CA 2OXWA 4AUOA 1BM6A 2W15A 4FVLA 4L63A 4DPEA 1CQRA 4GR0A 1MNCA 3I7GA 5D7WA 1CXVA 4QKZA 3TS4A 1XFUA 3DPFA 4WK7A 3EDGA 1J7NA 4H76A 2YB9A 2MLRA 2DW1A 1A86A 1AKLA 1XUCA 1BKCA 3DTEA 4FXQA 1YP1A 3SHIA 3KMCA 3LEAA 3ELMA 4EFSA 2E3XA 4WKEA 4Q1LA 1QIBA 1BKCI 3B2ZA 3WV3A 1D8FA 3NX7A 4JIJA 1USNA 4PKUA 5B5OA 4A3WA 1G49A 2OXUA 1ZS0A 5LABA 1CIZA 1Q3AA 3P24A 5L7FA 3ZVSA 1AYKA 1OZ9A 1D7XA 4H84A 2EROA 1CAQA 1PWVA 2Y6DA 4G9LA 1WNIA 2RJQA 1UEAA 4GR3A 3F19A 3LJZA 1O0QA 2WO8A 4L6TA 3KMEA 1BZSA 1JK3A 2X7MA 1HTDA 1GE5A 3OHOA 1FLSA
chains in the Genus database with same CATH topology
1R54A 4L19A 1C7KA 4HX3A 3HBUP 3DWBA 3LUNA 3F1AA 1FM1A 4WF6A 2USNA 1JAOA 3MA2A 1PWUA 5L79A 1HOVA 1IABA 3U1RA 1CGFA 1RM8A 1JJ9A 1G05A 1K7GA 1SU3A 1PWPA 4G0DA 3KECA 1UMSA 1YOUA 5D1SA 4I35A 1SRPA 4H1QA 4FU4A 4FXYP 3DTIA 3LKAA 1QICA 1UTTA 3F16A 3LILA 3OHLA 2W13A 2XS4A 3L0VA 3HBVP 3N2UA 3V96B 2OW0A 1UMTA 1XFYA 1DTHA 2DDFA 1OM7A 456CA 1C8TA 4H3XA 4PKQA 5JMYA 5H8XA 4ZR5A 3HYGA 2YUFA 1RMZA 1PWQA 1GE6A 1S4BP 3LUMA 5BOYA 3GBOA 1JH1A 1EUBA 1O0TA 3RTSA 2YIGA 1R55A 3EDIA 1SATA 4AIGA 4CTHA 1OO9A 1IADA 4XM7A 1IAEA 3HY9A 5I2ZA 2SRTA 1XUDA 3LQ0A 2TCLA 2X3BA 1G4KA 2A8HA 5B5PA 1GKDA 5BOTA 4WZVA 1IACA 4PKTA 1XFVA 3F17A 3DNGA 3AYKA 3HDBA 5I12A 2CLTA 4R3VA 1GXDA 2FV9A 3UVCA 1KUHA 1XURA 2W12A 3TVCA 5I0LA 2JSDA 4IUWA 2OY2A 2DDYA 1GO7P 4GR8A 4GWMA 3F18A 1HY7A 1H71P 3O64A 2OVZA 2RJPA 4JP4A 1BUVM 2X3CA 2OW1A 3KWVC 1MMRA 1IAGA 3EHXA 2D1OA 1I76A 1CK7A 5D3CA 3EDZA 1BSWA 1QJJA 1YQYA 2WO9A 1BUDA 4AYKA 4XBHA 1JIWP 2JT6A 1KUKA 2I47A 2XS3A 3LJGA 3TT4A 4GF1A 4DD8A 1CGEA 4I03A 1K7QA 3O2XA 2OI0A 1L6JA 3VI1A 1KUFA 3KEJA 4GWNA 4ILWD 4PKRA 4JA1A 1UTZA 1HFSA 1R1JA 1KUIA 2JNPA 2QPJA 4H49A 1ASTA 3EHYA 3LJTA 1GE7A 1KBCA 3LK8A 1I73A 1K7IA 1OM6A 3HY7A 2MLSA 2MZIA 2O36A 1BKCE 4XCTA 1KAPP 1XFZA 5D1TA 1I1IP 1HFCA 1JAQA 2OW9A 1EB6A 1Y93A 2L0RA 2JIHA 5CZMA 3ZUKA 3LE9A 2AIGP 4JPAA 1QJIA 2DW2A 1R1HA 2W0DA 2Z2DA 2K2GA 5I4OA 3B8ZA 2J83A 3Q2HA 3WV2A 5I3MA 1ZXVA 1FBLA 2OW2A 1XFXA 1ROSA 3KEKA 4IN9A 3G42A 2N8RA 3L0TA 2DW0A 3LIRA 3LMCA 2JT5A 1MMBA 1EAKA 2WOAA 3AYUA 5CUHA 1BIWA 2E2DA 3F15A 966CA 4IJOA 3DTKA 1BQOA 1ND1A 1B8YA 3LIKA 3P1VA 2AYKA 1SLMA 3ZXHA 1MMPA 1ATLA 4H30A 1CGLA 2OZRA 2ERQA 3TSKA 5BPAA 4H82A 3N2VA 1DMTA 4H2EA 3CKIA 4XM6A 3WV1A 3BA0A 4HMAA 830CA 1PWWA 1AF0A 3E8RA 4PKWA 2ERPA 2MZHA 1G9KA 3EWJA 5I43A 2J0TA 3KHIA 3AIGA 5D2BA 1GO8P 4JQGA 4A7BA 1B3DA 3G5CA 4PKSA 1SLNA 1OM8A 1GKCA 1JKYA 3HDAP 1D8MA 2KRJA 1JIZA 2FV5A 4ON1A 1YCMA 2D1NA 1D5JA 1XFWA 3EDHA 4DV8A 1ZVXA 2X3AA 2MZEA 1KUGA 1Z3JA 4GUYA 3RTTA 2OY4A 2Y6CA 4J4MA 1JANA 1IAAA 1OS2A 3DSLA 3LGPA 1Y8JA 1C3IA 2CKIA 1G12A 1QUAA 3K7NA 3B92A 5D1UA 1ZTQA 4XM8A 3DPEA 4L7AA 5CXAA 1A85A 3Q2GA 4PKVA 3KRYA 2W14A 4GQLA 4WKIA 3LQBA 3I7IA 1Y0VA 2V4BA 4DF9A 1ZXCA 1JAPA 1MMQA 3DL1A 3USNA 2HU6A 1OMJA 2OVXA 3HB2P 4AXQA 2POJA 1BQQM 1SMPA 1ZP5A 2O3EA 3K7LA 3VTGA 2PJTA 1R1IA 2OXZA 1HV5A 1QIAA 1OS9A 2K9CA 2OXWA 4AUOA 1BM6A 2W15A 4FVLA 4L63A 4DPEA 1CQRA 4GR0A 1MNCA 3I7GA 5D7WA 1CXVA 4QKZA 3TS4A 1XFUA 3DPFA 4WK7A 3EDGA 1J7NA 4H76A 2YB9A 2MLRA 2DW1A 1A86A 1AKLA 1XUCA 1BKCA 3DTEA 4FXQA 1YP1A 3SHIA 3KMCA 3LEAA 3ELMA 4EFSA 2E3XA 4WKEA 4Q1LA 1QIBA 1BKCI 3B2ZA 3WV3A 1D8FA 3NX7A 4JIJA 1USNA 4PKUA 5B5OA 4A3WA 1G49A 2OXUA 1ZS0A 5LABA 1CIZA 1Q3AA 3P24A 5L7FA 3ZVSA 1AYKA 1D7XA 4H84A 2EROA 1CAQA 1PWVA 2Y6DA 4G9LA 1WNIA 2RJQA 1UEAA 4GR3A 3F19A 3LJZA 1O0QA 2WO8A 4L6TA 3KMEA 1BZSA 1JK3A 2X7MA 1HTDA 1GE5A 3OHOA 1FLSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1R54 A;  4L19 A;  1C7K A;  4HX3 A;  3HBU P;  3DWB A;  3LUN A;  3F1A A;  1FM1 A;  4WF6 A;  2USN A;  1JAO A;  3MA2 A;  1PWU A;  5L79 A;  1HOV A;  1IAB A;  3U1R A;  1CGF A;  1RM8 A;  1JJ9 A;  1G05 A;  1K7G A;  1SU3 A;  1PWP A;  4G0D A;  3KEC A;  1UMS A;  1YOU A;  5D1S A;  4I35 A;  1SRP A;  4H1Q A;  4FU4 A;  4FXY P;  3LKA A;  1QIC A;  1UTT A;  3F16 A;  3LIL A;  3OHL A;  2W13 A;  2XS4 A;  3L0V A;  3HBV P;  3N2U A;  3V96 B;  2OW0 A;  1UMT A;  1XFY A;  1DTH A;  2DDF A;  1OM7 A;  456C A;  1C8T A;  4H3X A;  4PKQ A;  5JMY A;  5H8X A;  4ZR5 A;  3HYG A;  1RMZ A;  1PWQ A;  1GE6 A;  1S4B P;  3LUM A;  5BOY A;  3GBO A;  1JH1 A;  1EUB A;  1O0T A;  3RTS A;  2YIG A;  1R55 A;  3EDI A;  1SAT A;  4AIG A;  4CTH A;  1OO9 A;  1IAD A;  4XM7 A;  1IAE A;  3HY9 A;  5I2Z A;  2SRT A;  1XUD A;  3LQ0 A;  2TCL A;  2X3B A;  1G4K A;  2A8H A;  5B5P A;  1GKD A;  5BOT A;  4WZV A;  1IAC A;  4PKT A;  1XFV A;  3F17 A;  3DNG A;  3AYK A;  3HDB A;  5I12 A;  2CLT A;  4R3V A;  1GXD A;  2FV9 A;  3UVC A;  1KUH A;  1XUR A;  2W12 A;  3TVC A;  5I0L A;  2JSD A;  4IUW A;  2OY2 A;  2DDY A;  1GO7 P;  4GR8 A;  4GWM A;  3F18 A;  1HY7 A;  1H71 P;  3O64 A;  2OVZ A;  2RJP A;  4JP4 A;  1BUV M;  2X3C A;  2OW1 A;  3KWV C;  1MMR A;  1IAG A;  3EHX A;  2D1O A;  1I76 A;  1CK7 A;  5D3C A;  3EDZ A;  1BSW A;  1QJJ A;  1YQY A;  2WO9 A;  1BUD A;  4AYK A;  4XBH A;  1JIW P;  2JT6 A;  1KUK A;  2I47 A;  2XS3 A;  3LJG A;  3TT4 A;  4GF1 A;  4DD8 A;  1CGE A;  4I03 A;  1K7Q A;  3O2X A;  2OI0 A;  1L6J A;  3VI1 A;  1KUF A;  3KEJ A;  4GWN A;  4ILW D;  4PKR A;  4JA1 A;  1UTZ A;  1HFS A;  1R1J A;  1KUI A;  2JNP A;  2QPJ A;  4H49 A;  1AST A;  3EHY A;  3LJT A;  1GE7 A;  1KBC A;  3LK8 A;  1I73 A;  1K7I A;  1OM6 A;  3HY7 A;  2MLS A;  2MZI A;  2O36 A;  1BKC E;  4XCT A;  1KAP P;  1XFZ A;  5D1T A;  1I1I P;  1HFC A;  1JAQ A;  2OW9 A;  1EB6 A;  1Y93 A;  2L0R A;  2JIH A;  5CZM A;  3ZUK A;  3LE9 A;  2AIG P;  4JPA A;  1QJI A;  2DW2 A;  1R1H A;  2W0D A;  2Z2D A;  2K2G A;  5I4O A;  3B8Z A;  2J83 A;  3Q2H A;  3WV2 A;  5I3M A;  1ZXV A;  1FBL A;  2OW2 A;  1XFX A;  1ROS A;  3KEK A;  4IN9 A;  3G42 A;  2N8R A;  3L0T A;  2DW0 A;  3LIR A;  3LMC A;  2JT5 A;  1MMB A;  1EAK A;  2WOA A;  3AYU A;  5CUH A;  1BIW A;  2E2D A;  3F15 A;  966C A;  4IJO A;  1BQO A;  1ND1 A;  1B8Y A;  3LIK A;  3P1V A;  2AYK A;  1SLM A;  3ZXH A;  1MMP A;  1ATL A;  4H30 A;  1CGL A;  2OZR A;  2ERQ A;  3TSK A;  5BPA A;  4H82 A;  3N2V A;  1DMT A;  4H2E A;  3CKI A;  4XM6 A;  3WV1 A;  3BA0 A;  4HMA A;  830C A;  1PWW A;  1AF0 A;  3E8R A;  4PKW A;  2ERP A;  2MZH A;  1G9K A;  3EWJ A;  5I43 A;  2J0T A;  3KHI A;  3AIG A;  5D2B A;  1GO8 P;  4JQG A;  4A7B A;  1B3D A;  3G5C A;  4PKS A;  1SLN A;  1OM8 A;  1GKC A;  1JKY A;  3HDA P;  1D8M A;  2KRJ A;  1JIZ A;  2FV5 A;  4ON1 A;  1YCM A;  2D1N A;  1D5J A;  1XFW A;  3EDH A;  4DV8 A;  1ZVX A;  2X3A A;  2MZE A;  1KUG A;  1Z3J A;  4GUY A;  3RTT A;  2OY4 A;  2Y6C A;  4J4M A;  1JAN A;  1IAA A;  1OS2 A;  3DSL A;  3LGP A;  1Y8J A;  1C3I A;  2CKI A;  1G12 A;  1QUA A;  3K7N A;  3B92 A;  5D1U A;  1ZTQ A;  4XM8 A;  3DPE A;  5CXA A;  1A85 A;  3Q2G A;  4PKV A;  3KRY A;  2W14 A;  4GQL A;  4WKI A;  3LQB A;  3I7I A;  1Y0V A;  2V4B A;  4DF9 A;  1ZXC A;  1JAP A;  1MMQ A;  3DL1 A;  3USN A;  2HU6 A;  1OMJ A;  2OVX A;  3HB2 P;  4AXQ A;  2POJ A;  1BQQ M;  1SMP A;  1ZP5 A;  2O3E A;  3K7L A;  3VTG A;  2PJT A;  1R1I A;  2OXZ A;  1HV5 A;  1QIA A;  1OS9 A;  2K9C A;  2OXW A;  4AUO A;  1BM6 A;  2W15 A;  4FVL A;  4L63 A;  4DPE A;  1CQR A;  4GR0 A;  1MNC A;  3I7G A;  5D7W A;  1CXV A;  4QKZ A;  3TS4 A;  1XFU A;  3DPF A;  4WK7 A;  3EDG A;  1J7N A;  4H76 A;  2YB9 A;  2MLR A;  2DW1 A;  1A86 A;  1AKL A;  1XUC A;  1BKC A;  4FXQ A;  1YP1 A;  3SHI A;  3KMC A;  3LEA A;  3ELM A;  4EFS A;  2E3X A;  4WKE A;  4Q1L A;  1QIB A;  1BKC I;  3B2Z A;  3WV3 A;  1D8F A;  3NX7 A;  4JIJ A;  1USN A;  4PKU A;  5B5O A;  4A3W A;  1G49 A;  2OXU A;  1ZS0 A;  5LAB A;  1CIZ A;  1Q3A A;  3P24 A;  5L7F A;  3ZVS A;  1AYK A;  1D7X A;  4H84 A;  2ERO A;  1CAQ A;  1PWV A;  2Y6D A;  4G9L A;  1WNI A;  2RJQ A;  1UEA A;  4GR3 A;  3F19 A;  3LJZ A;  1O0Q A;  2WO8 A;  4L6T A;  3KME A;  1BZS A;  1JK3 A;  2X7M A;  1HTD A;  1GE5 A;  3OHO A;  1FLS A; 
#chains in the Genus database with same CATH topology
 1R54 A;  4L19 A;  1C7K A;  4HX3 A;  3HBU P;  3DWB A;  3LUN A;  3F1A A;  1FM1 A;  4WF6 A;  2USN A;  1JAO A;  3MA2 A;  1PWU A;  5L79 A;  1HOV A;  1IAB A;  3U1R A;  1CGF A;  1RM8 A;  1JJ9 A;  1G05 A;  1K7G A;  1SU3 A;  1PWP A;  4G0D A;  3KEC A;  1UMS A;  1YOU A;  5D1S A;  4I35 A;  1SRP A;  4H1Q A;  4FU4 A;  4FXY P;  3DTI A;  3LKA A;  1QIC A;  1UTT A;  3F16 A;  3LIL A;  3OHL A;  2W13 A;  2XS4 A;  3L0V A;  3HBV P;  3N2U A;  3V96 B;  2OW0 A;  1UMT A;  1XFY A;  1DTH A;  2DDF A;  1OM7 A;  456C A;  1C8T A;  4H3X A;  4PKQ A;  5JMY A;  5H8X A;  4ZR5 A;  3HYG A;  2YUF A;  1RMZ A;  1PWQ A;  1GE6 A;  1S4B P;  3LUM A;  5BOY A;  3GBO A;  1JH1 A;  1EUB A;  1O0T A;  3RTS A;  2YIG A;  1R55 A;  3EDI A;  1SAT A;  4AIG A;  4CTH A;  1OO9 A;  1IAD A;  4XM7 A;  1IAE A;  3HY9 A;  5I2Z A;  2SRT A;  1XUD A;  3LQ0 A;  2TCL A;  2X3B A;  1G4K A;  2A8H A;  5B5P A;  1GKD A;  5BOT A;  4WZV A;  1IAC A;  4PKT A;  1XFV A;  3F17 A;  3DNG A;  3AYK A;  3HDB A;  5I12 A;  2CLT A;  4R3V A;  1GXD A;  2FV9 A;  3UVC A;  1KUH A;  1XUR A;  2W12 A;  3TVC A;  5I0L A;  2JSD A;  4IUW A;  2OY2 A;  2DDY A;  1GO7 P;  4GR8 A;  4GWM A;  3F18 A;  1HY7 A;  1H71 P;  3O64 A;  2OVZ A;  2RJP A;  4JP4 A;  1BUV M;  2X3C A;  2OW1 A;  3KWV C;  1MMR A;  1IAG A;  3EHX A;  2D1O A;  1I76 A;  1CK7 A;  5D3C A;  3EDZ A;  1BSW A;  1QJJ A;  1YQY A;  2WO9 A;  1BUD A;  4AYK A;  4XBH A;  1JIW P;  2JT6 A;  1KUK A;  2I47 A;  2XS3 A;  3LJG A;  3TT4 A;  4GF1 A;  4DD8 A;  1CGE A;  4I03 A;  1K7Q A;  3O2X A;  2OI0 A;  1L6J A;  3VI1 A;  1KUF A;  3KEJ A;  4GWN A;  4ILW D;  4PKR A;  4JA1 A;  1UTZ A;  1HFS A;  1R1J A;  1KUI A;  2JNP A;  2QPJ A;  4H49 A;  1AST A;  3EHY A;  3LJT A;  1GE7 A;  1KBC A;  3LK8 A;  1I73 A;  1K7I A;  1OM6 A;  3HY7 A;  2MLS A;  2MZI A;  2O36 A;  1BKC E;  4XCT A;  1KAP P;  1XFZ A;  5D1T A;  1I1I P;  1HFC A;  1JAQ A;  2OW9 A;  1EB6 A;  1Y93 A;  2L0R A;  2JIH A;  5CZM A;  3ZUK A;  3LE9 A;  2AIG P;  4JPA A;  1QJI A;  2DW2 A;  1R1H A;  2W0D A;  2Z2D A;  2K2G A;  5I4O A;  3B8Z A;  2J83 A;  3Q2H A;  3WV2 A;  5I3M A;  1ZXV A;  1FBL A;  2OW2 A;  1XFX A;  1ROS A;  3KEK A;  1XM5 A;  4IN9 A;  3G42 A;  2N8R A;  3L0T A;  2DW0 A;  3LIR A;  3LMC A;  2JT5 A;  1MMB A;  1EAK A;  2WOA A;  3AYU A;  5CUH A;  1BIW A;  2E2D A;  3F15 A;  966C A;  4IJO A;  3DTK A;  1BQO A;  1ND1 A;  1B8Y A;  3LIK A;  3P1V A;  2AYK A;  1SLM A;  3ZXH A;  1MMP A;  1ATL A;  4H30 A;  1CGL A;  2OZR A;  2ERQ A;  3TSK A;  5BPA A;  4H82 A;  3N2V A;  1DMT A;  4H2E A;  3CKI A;  4XM6 A;  3WV1 A;  3BA0 A;  4HMA A;  830C A;  1PWW A;  1AF0 A;  3E8R A;  4PKW A;  2ERP A;  2MZH A;  1G9K A;  3EWJ A;  5I43 A;  2J0T A;  3KHI A;  3AIG A;  5D2B A;  1GO8 P;  4JQG A;  4A7B A;  1B3D A;  3G5C A;  4PKS A;  1TVI A;  1SLN A;  1OM8 A;  1GKC A;  1JKY A;  3HDA P;  1D8M A;  2KRJ A;  1JIZ A;  2FV5 A;  4ON1 A;  1YCM A;  2D1N A;  1D5J A;  1XFW A;  3EDH A;  4DV8 A;  1ZVX A;  2X3A A;  2MZE A;  1KUG A;  1Z3J A;  4GUY A;  3RTT A;  2OY4 A;  2Y6C A;  4J4M A;  1JAN A;  1IAA A;  1OS2 A;  3DSL A;  3LGP A;  1Y8J A;  1XAX A;  1C3I A;  2CKI A;  1G12 A;  1QUA A;  3K7N A;  3B92 A;  5D1U A;  1ZTQ A;  4XM8 A;  3DPE A;  4L7A A;  5CXA A;  1A85 A;  3Q2G A;  4PKV A;  3KRY A;  2W14 A;  4GQL A;  4WKI A;  3LQB A;  3I7I A;  1Y0V A;  2V4B A;  4DF9 A;  1ZXC A;  1JAP A;  1MMQ A;  3DL1 A;  3USN A;  2HU6 A;  1OMJ A;  2OVX A;  3HB2 P;  4AXQ A;  2POJ A;  1BQQ M;  1SMP A;  1ZP5 A;  2O3E A;  3K7L A;  3VTG A;  2PJT A;  1R1I A;  2OXZ A;  1HV5 A;  1QIA A;  1OS9 A;  2K9C A;  2OXW A;  4AUO A;  1BM6 A;  2W15 A;  4FVL A;  4L63 A;  4DPE A;  1CQR A;  4GR0 A;  1MNC A;  3I7G A;  5D7W A;  1CXV A;  4QKZ A;  3TS4 A;  1XFU A;  3DPF A;  4WK7 A;  3EDG A;  1J7N A;  4H76 A;  2YB9 A;  2MLR A;  2DW1 A;  1A86 A;  1AKL A;  1XUC A;  1BKC A;  3DTE A;  4FXQ A;  1YP1 A;  3SHI A;  3KMC A;  3LEA A;  3ELM A;  4EFS A;  2E3X A;  4WKE A;  4Q1L A;  1QIB A;  1BKC I;  3B2Z A;  3WV3 A;  1D8F A;  3NX7 A;  4JIJ A;  1USN A;  4PKU A;  5B5O A;  4A3W A;  1G49 A;  2OXU A;  1ZS0 A;  5LAB A;  1CIZ A;  1Q3A A;  3P24 A;  5L7F A;  3ZVS A;  1AYK A;  1OZ9 A;  1D7X A;  4H84 A;  2ERO A;  1CAQ A;  1PWV A;  2Y6D A;  4G9L A;  1WNI A;  2RJQ A;  1UEA A;  4GR3 A;  3F19 A;  3LJZ A;  1O0Q A;  2WO8 A;  4L6T A;  3KME A;  1BZS A;  1JK3 A;  2X7M A;  1HTD A;  1GE5 A;  3OHO A;  1FLS A; 
#chains in the Genus database with same CATH homology
 1R54 A;  4L19 A;  1C7K A;  4HX3 A;  3HBU P;  3DWB A;  3LUN A;  3F1A A;  1FM1 A;  4WF6 A;  2USN A;  1JAO A;  3MA2 A;  1PWU A;  5L79 A;  1HOV A;  1IAB A;  3U1R A;  1CGF A;  1RM8 A;  1JJ9 A;  1G05 A;  1K7G A;  1SU3 A;  1PWP A;  4G0D A;  3KEC A;  1UMS A;  1YOU A;  5D1S A;  4I35 A;  1SRP A;  4H1Q A;  4FU4 A;  4FXY P;  3DTI A;  3LKA A;  1QIC A;  1UTT A;  3F16 A;  3LIL A;  3OHL A;  2W13 A;  2XS4 A;  3L0V A;  3HBV P;  3N2U A;  3V96 B;  2OW0 A;  1UMT A;  1XFY A;  1DTH A;  2DDF A;  1OM7 A;  456C A;  1C8T A;  4H3X A;  4PKQ A;  5JMY A;  5H8X A;  4ZR5 A;  3HYG A;  2YUF A;  1RMZ A;  1PWQ A;  1GE6 A;  1S4B P;  3LUM A;  5BOY A;  3GBO A;  1JH1 A;  1EUB A;  1O0T A;  3RTS A;  2YIG A;  1R55 A;  3EDI A;  1SAT A;  4AIG A;  4CTH A;  1OO9 A;  1IAD A;  4XM7 A;  1IAE A;  3HY9 A;  5I2Z A;  2SRT A;  1XUD A;  3LQ0 A;  2TCL A;  2X3B A;  1G4K A;  2A8H A;  5B5P A;  1GKD A;  5BOT A;  4WZV A;  1IAC A;  4PKT A;  1XFV A;  3F17 A;  3DNG A;  3AYK A;  3HDB A;  5I12 A;  2CLT A;  4R3V A;  1GXD A;  2FV9 A;  3UVC A;  1KUH A;  1XUR A;  2W12 A;  3TVC A;  5I0L A;  2JSD A;  4IUW A;  2OY2 A;  2DDY A;  1GO7 P;  4GR8 A;  4GWM A;  3F18 A;  1HY7 A;  1H71 P;  3O64 A;  2OVZ A;  2RJP A;  4JP4 A;  1BUV M;  2X3C A;  2OW1 A;  3KWV C;  1MMR A;  1IAG A;  3EHX A;  2D1O A;  1I76 A;  1CK7 A;  5D3C A;  3EDZ A;  1BSW A;  1QJJ A;  1YQY A;  2WO9 A;  1BUD A;  4AYK A;  4XBH A;  1JIW P;  2JT6 A;  1KUK A;  2I47 A;  2XS3 A;  3LJG A;  3TT4 A;  4GF1 A;  4DD8 A;  1CGE A;  4I03 A;  1K7Q A;  3O2X A;  2OI0 A;  1L6J A;  3VI1 A;  1KUF A;  3KEJ A;  4GWN A;  4ILW D;  4PKR A;  4JA1 A;  1UTZ A;  1HFS A;  1R1J A;  1KUI A;  2JNP A;  2QPJ A;  4H49 A;  1AST A;  3EHY A;  3LJT A;  1GE7 A;  1KBC A;  3LK8 A;  1I73 A;  1K7I A;  1OM6 A;  3HY7 A;  2MLS A;  2MZI A;  2O36 A;  1BKC E;  4XCT A;  1KAP P;  1XFZ A;  5D1T A;  1I1I P;  1HFC A;  1JAQ A;  2OW9 A;  1EB6 A;  1Y93 A;  2L0R A;  2JIH A;  5CZM A;  3ZUK A;  3LE9 A;  2AIG P;  4JPA A;  1QJI A;  2DW2 A;  1R1H A;  2W0D A;  2Z2D A;  2K2G A;  5I4O A;  3B8Z A;  2J83 A;  3Q2H A;  3WV2 A;  5I3M A;  1ZXV A;  1FBL A;  2OW2 A;  1XFX A;  1ROS A;  3KEK A;  4IN9 A;  3G42 A;  2N8R A;  3L0T A;  2DW0 A;  3LIR A;  3LMC A;  2JT5 A;  1MMB A;  1EAK A;  2WOA A;  3AYU A;  5CUH A;  1BIW A;  2E2D A;  3F15 A;  966C A;  4IJO A;  3DTK A;  1BQO A;  1ND1 A;  1B8Y A;  3LIK A;  3P1V A;  2AYK A;  1SLM A;  3ZXH A;  1MMP A;  1ATL A;  4H30 A;  1CGL A;  2OZR A;  2ERQ A;  3TSK A;  5BPA A;  4H82 A;  3N2V A;  1DMT A;  4H2E A;  3CKI A;  4XM6 A;  3WV1 A;  3BA0 A;  4HMA A;  830C A;  1PWW A;  1AF0 A;  3E8R A;  4PKW A;  2ERP A;  2MZH A;  1G9K A;  3EWJ A;  5I43 A;  2J0T A;  3KHI A;  3AIG A;  5D2B A;  1GO8 P;  4JQG A;  4A7B A;  1B3D A;  3G5C A;  4PKS A;  1SLN A;  1OM8 A;  1GKC A;  1JKY A;  3HDA P;  1D8M A;  2KRJ A;  1JIZ A;  2FV5 A;  4ON1 A;  1YCM A;  2D1N A;  1D5J A;  1XFW A;  3EDH A;  4DV8 A;  1ZVX A;  2X3A A;  2MZE A;  1KUG A;  1Z3J A;  4GUY A;  3RTT A;  2OY4 A;  2Y6C A;  4J4M A;  1JAN A;  1IAA A;  1OS2 A;  3DSL A;  3LGP A;  1Y8J A;  1C3I A;  2CKI A;  1G12 A;  1QUA A;  3K7N A;  3B92 A;  5D1U A;  1ZTQ A;  4XM8 A;  3DPE A;  4L7A A;  5CXA A;  1A85 A;  3Q2G A;  4PKV A;  3KRY A;  2W14 A;  4GQL A;  4WKI A;  3LQB A;  3I7I A;  1Y0V A;  2V4B A;  4DF9 A;  1ZXC A;  1JAP A;  1MMQ A;  3DL1 A;  3USN A;  2HU6 A;  1OMJ A;  2OVX A;  3HB2 P;  4AXQ A;  2POJ A;  1BQQ M;  1SMP A;  1ZP5 A;  2O3E A;  3K7L A;  3VTG A;  2PJT A;  1R1I A;  2OXZ A;  1HV5 A;  1QIA A;  1OS9 A;  2K9C A;  2OXW A;  4AUO A;  1BM6 A;  2W15 A;  4FVL A;  4L63 A;  4DPE A;  1CQR A;  4GR0 A;  1MNC A;  3I7G A;  5D7W A;  1CXV A;  4QKZ A;  3TS4 A;  1XFU A;  3DPF A;  4WK7 A;  3EDG A;  1J7N A;  4H76 A;  2YB9 A;  2MLR A;  2DW1 A;  1A86 A;  1AKL A;  1XUC A;  1BKC A;  3DTE A;  4FXQ A;  1YP1 A;  3SHI A;  3KMC A;  3LEA A;  3ELM A;  4EFS A;  2E3X A;  4WKE A;  4Q1L A;  1QIB A;  1BKC I;  3B2Z A;  3WV3 A;  1D8F A;  3NX7 A;  4JIJ A;  1USN A;  4PKU A;  5B5O A;  4A3W A;  1G49 A;  2OXU A;  1ZS0 A;  5LAB A;  1CIZ A;  1Q3A A;  3P24 A;  5L7F A;  3ZVS A;  1AYK A;  1D7X A;  4H84 A;  2ERO A;  1CAQ A;  1PWV A;  2Y6D A;  4G9L A;  1WNI A;  2RJQ A;  1UEA A;  4GR3 A;  3F19 A;  3LJZ A;  1O0Q A;  2WO8 A;  4L6T A;  3KME A;  1BZS A;  1JK3 A;  2X7M A;  1HTD A;  1GE5 A;  3OHO A;  1FLS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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