4I03A

Human mmp12 in complex with a peg-linked bifunctional l-glutamate motif inhibitor
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
159
structure length
159
Chain Sequence
MGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHAIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallization of bi-functional ligand protein complexes.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Macrophage metalloelastase
total genus 46
structure length 159
sequence length 159
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2012-11-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 4i03A00
4XM6A 1IADA 3KEKA 1UMTA 1GKCA 1JAOA 5CZMA 3HYGA 5L7FA 1H71P 2DDFA 1SU3A 4H30A 3F1AA 1UTZA 5I0LA 1XUCA 3P1VA 3HBVP 3KECA 5JMYA 2W14A 3EHYA 4PKSA 2OY4A 3MA2A 1YQYA 5D3CA 3F18A 4J4MA 1XFXA 2X7MA 3U1RA 3F19A 1BSWA 1Q3AA 1MMBA 2DDYA 3L0VA 1YCMA 2K9CA 4WKEA 2OW1A 3DPEA 4PKRA 1QJIA 3GBOA 1QIAA 1ZXCA 2DW0A 3N2UA 1BKCI 4ZR5A 5I43A 3CKIA 1WNIA 3LUNA 1QIBA 4IUWA 4PKTA 1MNCA 3HBUP 2DW2A 3TVCA 1KBCA 3DWBA 1ZS0A 1BQOA 2TCLA 4H3XA 2ERQA 2USNA 3OHOA 1EAKA 4JIJA 4L6TA 2W12A 1KUIA 1OMJA 1BKCA 4H84A 1CGFA 1R55A 1G9KA 1HV5A 3B2ZA 5D1TA 3TS4A 1Y8JA 2JT5A 4PKVA 1QICA 3KWVC 3HDBA 3USNA 1D7XA 3I7IA 4JA1A 2W15A 2D1NA 1D8MA 3B8ZA 1BKCE 3ZVSA 3F16A 4WZVA 1C3IA 1D8FA 3F15A 1KUKA 3KHIA 3EHXA 4A7BA 1YOUA 4GWMA 1JJ9A 1GO7P 5D2BA 1AF0A 4AUOA 1BUVM 5B5OA 4JPAA 2QPJA 1XFYA 3DNGA 1GO8P 3HDAP 1R1IA 1DTHA 1C7KA 4L19A 1KUFA 1CQRA 2JSDA 1B8YA 5CUHA 1EUBA 2Z2DA 1UEAA 1KUGA 3LJTA 2SRTA 1XFWA 1SLNA 1OM7A 1YP1A 3TT4A 5I12A 3LK8A 4L63A 3TSKA 2CLTA 2OVZA 4GF1A 2E2DA 1ZP5A 2X3BA 3LGPA 2D1OA 3O64A 3LE9A 2J0TA 4H1QA 2V4BA 3HY7A 1JIWP 1OS2A 2MZHA 3UVCA 1ND1A 4AXQA 2OW2A 1MMPA 1IACA 3LEAA 1JAQA 1K7IA 3E8RA 4AIGA 2HU6A 3ELMA 1R1JA 1K7GA 4ON1A 2JNPA 5D1SA 1PWWA 3LUMA 3LQBA 2XS4A 1XFVA 1AYKA 1AKLA 2AIGP 4H82A 2N8RA 1GE7A 1SMPA 4WK7A 2E3XA 1PWVA 2FV5A 1RM8A 4H76A 2OXUA 1I1IP 3G5CA 1BZSA 3F17A 4QKZA 4DF9A 1FLSA 2OW0A 830CA 1I73A 3WV3A 1MMQA 4CTHA 4GQLA 1CK7A 1L6JA 4JQGA 1FM1A 1DMTA 1OS9A 2MLSA 4XM7A 3RTTA 2K2GA 2OVXA 3KMCA 1O0TA 4I03A 4XM8A 4JP4A 3N2VA 3O2XA 4H49A 5BOYA 2J83A 1OO9A 3RTSA 1G12A 3I7GA 1BQQM 4PKUA 3EDIA 1ASTA 4HMAA 2WO9A 2RJPA 2PJTA 2RJQA 2WOAA 3VI1A 5D1UA 2O36A 3ZXHA 3LMCA 1JKYA 1JH1A 2XS3A 3LIRA 1KAPP 1JANA 5B5PA 3SHIA 5LABA 3VTGA 1UTTA 1BUDA 1O0QA 3V96B 4AYKA 1A85A 1R54A 3OHLA 4FU4A 4G9LA 1JAPA 3NX7A 1CAQA 1HY7A 1CGEA 3G42A 3AYUA 2X3AA 5D7WA 4Q1LA 4GUYA 4DV8A 2W13A 1CGLA 1J7NA 2A8HA 5I4OA 1GXDA 2POJA 1PWPA 1KUHA 1ATLA 3LJGA 2OXZA 2ERPA 1USNA 2JT6A 1ZXVA 2CKIA 1BM6A 1HOVA 1D5JA 1ZTQA 2L0RA 1XUDA 1G49A 4WF6A 3LJZA 2OI0A 3BA0A 4XCTA 2O3EA 1R1HA 3Q2HA 1XURA 1K7QA 1GKDA 3EDZA 2OZRA 2DW1A 2Y6DA 1Z3JA 4H2EA 1CXVA 1G4KA 1MMRA 2FV9A 2MZEA 3LILA 1RMZA 3DPFA 2KRJA 3EDHA 456CA 1BIWA 3DL1A 2MLRA 5BPAA 4I35A 1XFZA 1JIZA 2OXWA 2W0DA 3K7NA 1OM8A 4R3VA 1HTDA 1Y0VA 4IJOA 4PKQA 4G0DA 1ZVXA 1Y93A 2AYKA 1A86A 3AIGA 4DPEA 5L79A 1HFSA 966CA 3P24A 1SRPA 3AYKA 4XBHA 1C8TA 3LKAA 3LQ0A 3B92A 1ROSA 1SLMA 4A3WA 1IAEA 4FXYP 5BOTA 1QJJA 2YB9A 1PWQA 2Y6CA 5I2ZA 2MZIA 2EROA 1IAAA 2X3CA 3EWJA 4DD8A 5H8XA 4PKWA 1UMSA 5I3MA 4IN9A 1JK3A 1QUAA 2OW9A 1G05A 3WV2A 1I76A 3KEJA 1GE5A 3HB2P 1IABA 3DSLA 1B3DA 4WKIA 1PWUA 1EB6A 2OY2A 4ILWD 4FVLA 1FBLA 1HFCA 1GE6A 2JIHA 4FXQA 1XFUA 1S4BP 2YIGA 4HX3A 1CIZA 2I47A 3WV1A 4GR8A 3Q2GA 3KMEA 2WO8A 3EDGA 5CXAA 4GR3A 4GWNA 3L0TA 3HY9A 3LIKA 4GR0A 3KRYA 3K7LA 1IAGA 3ZUKA 1SATA 1OM6A 4EFSA
chains in the Genus database with same CATH superfamily
4XM6A 1IADA 3KEKA 1UMTA 1GKCA 1JAOA 5CZMA 3HYGA 5L7FA 1H71P 2DDFA 1SU3A 4H30A 3F1AA 1UTZA 5I0LA 1XUCA 3P1VA 3HBVP 3KECA 5JMYA 2W14A 3EHYA 4PKSA 2OY4A 3MA2A 1YQYA 5D3CA 3F18A 4J4MA 1XFXA 2X7MA 3U1RA 1XAXA 3F19A 1BSWA 1Q3AA 1MMBA 2DDYA 3L0VA 1YCMA 2K9CA 4WKEA 2OW1A 3DPEA 4PKRA 1QJIA 3GBOA 1QIAA 1ZXCA 2DW0A 3N2UA 1BKCI 4ZR5A 5I43A 3CKIA 1WNIA 3LUNA 1QIBA 4IUWA 4PKTA 1MNCA 3HBUP 2DW2A 3TVCA 1KBCA 3DWBA 1ZS0A 1BQOA 2TCLA 4H3XA 2ERQA 2USNA 3OHOA 1EAKA 4JIJA 4L6TA 2W12A 1KUIA 1OMJA 1BKCA 4H84A 1CGFA 1R55A 1G9KA 1HV5A 3B2ZA 5D1TA 3DTEA 3TS4A 1Y8JA 2JT5A 4PKVA 1QICA 3KWVC 3HDBA 3USNA 1D7XA 3I7IA 4JA1A 2W15A 2D1NA 1D8MA 3B8ZA 1BKCE 3ZVSA 3F16A 4WZVA 1C3IA 1D8FA 3F15A 1KUKA 3KHIA 3EHXA 4A7BA 1YOUA 4GWMA 1JJ9A 1GO7P 5D2BA 1AF0A 4AUOA 1BUVM 5B5OA 4JPAA 2QPJA 1XFYA 3DNGA 1GO8P 3HDAP 1R1IA 1DTHA 1C7KA 4L19A 1KUFA 1CQRA 2JSDA 1B8YA 5CUHA 1EUBA 2Z2DA 1UEAA 1KUGA 3LJTA 2SRTA 1XFWA 1SLNA 1OM7A 1YP1A 3TT4A 5I12A 3LK8A 4L63A 3TSKA 2CLTA 2OVZA 4GF1A 2E2DA 1ZP5A 2X3BA 3LGPA 3DTIA 2D1OA 3O64A 3LE9A 2J0TA 4H1QA 2V4BA 3HY7A 1JIWP 1OS2A 2MZHA 3UVCA 1ND1A 4AXQA 2OW2A 1MMPA 1IACA 3LEAA 1JAQA 1K7IA 3E8RA 4AIGA 2HU6A 3ELMA 1R1JA 1OZ9A 1K7GA 4ON1A 2JNPA 5D1SA 1PWWA 3LUMA 3LQBA 2XS4A 1XFVA 1AYKA 1AKLA 2AIGP 4H82A 2N8RA 1GE7A 1SMPA 4WK7A 2E3XA 1PWVA 2FV5A 1RM8A 4H76A 2OXUA 1I1IP 3G5CA 1BZSA 3F17A 4QKZA 4DF9A 1FLSA 2OW0A 830CA 1I73A 3WV3A 1MMQA 4CTHA 4GQLA 1CK7A 1L6JA 4JQGA 1FM1A 1DMTA 1OS9A 2MLSA 4XM7A 3RTTA 2K2GA 2OVXA 3KMCA 4L7AA 1O0TA 4I03A 4XM8A 4JP4A 3N2VA 3O2XA 4H49A 5BOYA 2J83A 1OO9A 3RTSA 1G12A 3I7GA 1BQQM 4PKUA 3EDIA 1ASTA 1XM5A 2WO9A 4HMAA 2RJPA 2PJTA 2RJQA 2WOAA 3VI1A 5D1UA 2O36A 3ZXHA 3LMCA 1JKYA 1JH1A 2XS3A 3LIRA 1KAPP 1JANA 5B5PA 3SHIA 5LABA 3VTGA 1UTTA 1BUDA 1O0QA 3V96B 4AYKA 1A85A 1R54A 3OHLA 4FU4A 4G9LA 1JAPA 3NX7A 1CAQA 1HY7A 1CGEA 3G42A 3AYUA 2X3AA 5D7WA 4Q1LA 4GUYA 4DV8A 2W13A 1CGLA 1J7NA 2A8HA 5I4OA 1GXDA 2POJA 1PWPA 1KUHA 1ATLA 3LJGA 2OXZA 2ERPA 1USNA 2JT6A 1ZXVA 2CKIA 1BM6A 1HOVA 1D5JA 1ZTQA 2L0RA 1XUDA 1G49A 4WF6A 3LJZA 2OI0A 3BA0A 4XCTA 2O3EA 1R1HA 3Q2HA 1XURA 1K7QA 1GKDA 3EDZA 2OZRA 2DW1A 2Y6DA 1Z3JA 4H2EA 1CXVA 1G4KA 1MMRA 2FV9A 2MZEA 3LILA 1RMZA 3DPFA 2KRJA 1TVIA 3EDHA 456CA 1BIWA 3DL1A 2MLRA 5BPAA 4I35A 1XFZA 1JIZA 2OXWA 2W0DA 3K7NA 1OM8A 4R3VA 1HTDA 1Y0VA 4IJOA 4PKQA 4G0DA 1ZVXA 1Y93A 2AYKA 1A86A 3AIGA 4DPEA 5L79A 1HFSA 966CA 3P24A 1SRPA 3AYKA 4XBHA 1C8TA 3LKAA 3LQ0A 3B92A 1ROSA 1SLMA 4A3WA 1IAEA 4FXYP 5BOTA 1QJJA 2YB9A 1PWQA 2Y6CA 5I2ZA 2MZIA 2EROA 1IAAA 2X3CA 3EWJA 4DD8A 5H8XA 4PKWA 1UMSA 5I3MA 4IN9A 1JK3A 1QUAA 3DTKA 2OW9A 1G05A 3WV2A 1I76A 3KEJA 1GE5A 3HB2P 1IABA 3DSLA 1B3DA 4WKIA 1PWUA 1EB6A 2OY2A 4ILWD 4FVLA 1FBLA 1HFCA 1GE6A 2JIHA 4FXQA 1XFUA 1S4BP 2YIGA 4HX3A 1CIZA 2I47A 3WV1A 2YUFA 4GR8A 3Q2GA 3KMEA 2WO8A 3EDGA 5CXAA 4GR3A 4GWNA 3L0TA 3HY9A 3LIKA 4GR0A 3KRYA 3K7LA 1IAGA 3ZUKA 1SATA 1OM6A 4EFSA
chains in the Genus database with same CATH topology
4XM6A 1IADA 3KEKA 1UMTA 1GKCA 1JAOA 5CZMA 3HYGA 5L7FA 1H71P 2DDFA 1SU3A 4H30A 3F1AA 1UTZA 5I0LA 1XUCA 3P1VA 3HBVP 3KECA 5JMYA 2W14A 3EHYA 4PKSA 2OY4A 3MA2A 1YQYA 5D3CA 3F18A 4J4MA 1XFXA 2X7MA 3U1RA 3F19A 1BSWA 1Q3AA 1MMBA 2DDYA 3L0VA 1YCMA 2K9CA 4WKEA 2OW1A 3DPEA 4PKRA 1QJIA 3GBOA 1QIAA 1ZXCA 2DW0A 3N2UA 1BKCI 4ZR5A 5I43A 3CKIA 1WNIA 3LUNA 1QIBA 4IUWA 4PKTA 1MNCA 3HBUP 2DW2A 3TVCA 1KBCA 3DWBA 1ZS0A 1BQOA 2TCLA 4H3XA 2ERQA 2USNA 3OHOA 1EAKA 4JIJA 4L6TA 2W12A 1KUIA 1OMJA 1BKCA 4H84A 1CGFA 1R55A 1G9KA 1HV5A 3B2ZA 5D1TA 3DTEA 3TS4A 1Y8JA 2JT5A 4PKVA 1QICA 3KWVC 3HDBA 3USNA 1D7XA 3I7IA 4JA1A 2W15A 2D1NA 1D8MA 3B8ZA 1BKCE 3ZVSA 3F16A 4WZVA 1C3IA 1D8FA 3F15A 1KUKA 3KHIA 3EHXA 4A7BA 1YOUA 4GWMA 1JJ9A 1GO7P 5D2BA 1AF0A 4AUOA 1BUVM 5B5OA 4JPAA 2QPJA 1XFYA 3DNGA 1GO8P 3HDAP 1R1IA 1DTHA 1C7KA 4L19A 1KUFA 1CQRA 2JSDA 1B8YA 5CUHA 1EUBA 2Z2DA 1UEAA 1KUGA 3LJTA 2SRTA 1XFWA 1SLNA 1OM7A 1YP1A 3TT4A 5I12A 3LK8A 4L63A 3TSKA 2CLTA 2OVZA 4GF1A 2E2DA 1ZP5A 2X3BA 3LGPA 3DTIA 2D1OA 3O64A 3LE9A 2J0TA 4H1QA 2V4BA 3HY7A 1JIWP 1OS2A 2MZHA 3UVCA 1ND1A 4AXQA 2OW2A 1MMPA 1IACA 3LEAA 1JAQA 1K7IA 3E8RA 4AIGA 2HU6A 3ELMA 1R1JA 1K7GA 4ON1A 2JNPA 5D1SA 1PWWA 3LUMA 3LQBA 2XS4A 1XFVA 1AYKA 1AKLA 2AIGP 4H82A 2N8RA 1GE7A 1SMPA 4WK7A 2E3XA 1PWVA 2FV5A 1RM8A 4H76A 2OXUA 1I1IP 3G5CA 1BZSA 3F17A 4QKZA 4DF9A 1FLSA 2OW0A 830CA 1I73A 3WV3A 1MMQA 4CTHA 4GQLA 1CK7A 1L6JA 4JQGA 1FM1A 1DMTA 1OS9A 2MLSA 4XM7A 3RTTA 2K2GA 2OVXA 3KMCA 4L7AA 1O0TA 4I03A 4XM8A 4JP4A 3N2VA 3O2XA 4H49A 5BOYA 2J83A 1OO9A 3RTSA 1G12A 3I7GA 1BQQM 4PKUA 3EDIA 1ASTA 4HMAA 2WO9A 2RJPA 2PJTA 2RJQA 2WOAA 3VI1A 5D1UA 2O36A 3ZXHA 3LMCA 1JKYA 1JH1A 2XS3A 3LIRA 1KAPP 1JANA 5B5PA 3SHIA 5LABA 3VTGA 1UTTA 1BUDA 1O0QA 3V96B 4AYKA 1A85A 1R54A 3OHLA 4FU4A 4G9LA 1JAPA 3NX7A 1CAQA 1HY7A 1CGEA 3G42A 3AYUA 2X3AA 5D7WA 4Q1LA 4GUYA 4DV8A 2W13A 1CGLA 1J7NA 2A8HA 5I4OA 1GXDA 2POJA 1PWPA 1KUHA 1ATLA 3LJGA 2OXZA 2ERPA 1USNA 2JT6A 1ZXVA 2CKIA 1BM6A 1HOVA 1D5JA 1ZTQA 2L0RA 1XUDA 1G49A 4WF6A 3LJZA 2OI0A 3BA0A 4XCTA 2O3EA 1R1HA 3Q2HA 1XURA 1K7QA 1GKDA 3EDZA 2OZRA 2DW1A 2Y6DA 1Z3JA 4H2EA 1CXVA 1G4KA 1MMRA 2FV9A 2MZEA 3LILA 1RMZA 3DPFA 2KRJA 3EDHA 456CA 1BIWA 3DL1A 2MLRA 5BPAA 4I35A 1XFZA 1JIZA 2OXWA 2W0DA 3K7NA 1OM8A 4R3VA 1HTDA 1Y0VA 4IJOA 4PKQA 4G0DA 1ZVXA 1Y93A 2AYKA 1A86A 3AIGA 4DPEA 5L79A 1HFSA 966CA 3P24A 1SRPA 3AYKA 4XBHA 1C8TA 3LKAA 3LQ0A 3B92A 1ROSA 1SLMA 4A3WA 1IAEA 4FXYP 5BOTA 1QJJA 2YB9A 1PWQA 2Y6CA 5I2ZA 2MZIA 2EROA 1IAAA 2X3CA 3EWJA 4DD8A 5H8XA 4PKWA 1UMSA 5I3MA 4IN9A 1JK3A 1QUAA 3DTKA 2OW9A 1G05A 3WV2A 1I76A 3KEJA 1GE5A 3HB2P 1IABA 3DSLA 1B3DA 4WKIA 1PWUA 1EB6A 2OY2A 4ILWD 4FVLA 1FBLA 1HFCA 1GE6A 2JIHA 4FXQA 1XFUA 1S4BP 2YIGA 4HX3A 1CIZA 2I47A 3WV1A 2YUFA 4GR8A 3Q2GA 3KMEA 2WO8A 3EDGA 5CXAA 4GR3A 4GWNA 3L0TA 3HY9A 3LIKA 4GR0A 3KRYA 3K7LA 1IAGA 3ZUKA 1SATA 1OM6A 4EFSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4XM6 A;  1IAD A;  3KEK A;  1UMT A;  1GKC A;  1JAO A;  5CZM A;  3HYG A;  5L7F A;  1H71 P;  2DDF A;  1SU3 A;  4H30 A;  3F1A A;  1UTZ A;  5I0L A;  1XUC A;  3P1V A;  3HBV P;  3KEC A;  5JMY A;  2W14 A;  3EHY A;  4PKS A;  2OY4 A;  3MA2 A;  1YQY A;  5D3C A;  3F18 A;  4J4M A;  1XFX A;  2X7M A;  3U1R A;  3F19 A;  1BSW A;  1Q3A A;  1MMB A;  2DDY A;  3L0V A;  1YCM A;  2K9C A;  4WKE A;  2OW1 A;  3DPE A;  4PKR A;  1QJI A;  3GBO A;  1QIA A;  1ZXC A;  2DW0 A;  3N2U A;  1BKC I;  4ZR5 A;  5I43 A;  3CKI A;  1WNI A;  3LUN A;  1QIB A;  4IUW A;  4PKT A;  1MNC A;  3HBU P;  2DW2 A;  3TVC A;  1KBC A;  3DWB A;  1ZS0 A;  1BQO A;  2TCL A;  4H3X A;  2ERQ A;  2USN A;  3OHO A;  1EAK A;  4JIJ A;  4L6T A;  2W12 A;  1KUI A;  1OMJ A;  1BKC A;  4H84 A;  1CGF A;  1R55 A;  1G9K A;  1HV5 A;  3B2Z A;  5D1T A;  3TS4 A;  1Y8J A;  2JT5 A;  4PKV A;  1QIC A;  3KWV C;  3HDB A;  3USN A;  1D7X A;  3I7I A;  4JA1 A;  2W15 A;  2D1N A;  1D8M A;  3B8Z A;  1BKC E;  3ZVS A;  3F16 A;  4WZV A;  1C3I A;  1D8F A;  3F15 A;  1KUK A;  3KHI A;  3EHX A;  4A7B A;  1YOU A;  4GWM A;  1JJ9 A;  1GO7 P;  5D2B A;  1AF0 A;  4AUO A;  1BUV M;  5B5O A;  4JPA A;  2QPJ A;  1XFY A;  3DNG A;  1GO8 P;  3HDA P;  1R1I A;  1DTH A;  1C7K A;  4L19 A;  1KUF A;  1CQR A;  2JSD A;  1B8Y A;  5CUH A;  1EUB A;  2Z2D A;  1UEA A;  1KUG A;  3LJT A;  2SRT A;  1XFW A;  1SLN A;  1OM7 A;  1YP1 A;  3TT4 A;  5I12 A;  3LK8 A;  4L63 A;  3TSK A;  2CLT A;  2OVZ A;  4GF1 A;  2E2D A;  1ZP5 A;  2X3B A;  3LGP A;  2D1O A;  3O64 A;  3LE9 A;  2J0T A;  4H1Q A;  2V4B A;  3HY7 A;  1JIW P;  1OS2 A;  2MZH A;  3UVC A;  1ND1 A;  4AXQ A;  2OW2 A;  1MMP A;  1IAC A;  3LEA A;  1JAQ A;  1K7I A;  3E8R A;  4AIG A;  2HU6 A;  3ELM A;  1R1J A;  1K7G A;  4ON1 A;  2JNP A;  5D1S A;  1PWW A;  3LUM A;  3LQB A;  2XS4 A;  1XFV A;  1AYK A;  1AKL A;  2AIG P;  4H82 A;  2N8R A;  1GE7 A;  1SMP A;  4WK7 A;  2E3X A;  1PWV A;  2FV5 A;  1RM8 A;  4H76 A;  2OXU A;  1I1I P;  3G5C A;  1BZS A;  3F17 A;  4QKZ A;  4DF9 A;  1FLS A;  2OW0 A;  830C A;  1I73 A;  3WV3 A;  1MMQ A;  4CTH A;  4GQL A;  1CK7 A;  1L6J A;  4JQG A;  1FM1 A;  1DMT A;  1OS9 A;  2MLS A;  4XM7 A;  3RTT A;  2K2G A;  2OVX A;  3KMC A;  1O0T A;  4I03 A;  4XM8 A;  4JP4 A;  3N2V A;  3O2X A;  4H49 A;  5BOY A;  2J83 A;  1OO9 A;  3RTS A;  1G12 A;  3I7G A;  1BQQ M;  4PKU A;  3EDI A;  1AST A;  4HMA A;  2WO9 A;  2RJP A;  2PJT A;  2RJQ A;  2WOA A;  3VI1 A;  5D1U A;  2O36 A;  3ZXH A;  3LMC A;  1JKY A;  1JH1 A;  2XS3 A;  3LIR A;  1KAP P;  1JAN A;  5B5P A;  3SHI A;  5LAB A;  3VTG A;  1UTT A;  1BUD A;  1O0Q A;  3V96 B;  4AYK A;  1A85 A;  1R54 A;  3OHL A;  4FU4 A;  4G9L A;  1JAP A;  3NX7 A;  1CAQ A;  1HY7 A;  1CGE A;  3G42 A;  3AYU A;  2X3A A;  5D7W A;  4Q1L A;  4GUY A;  4DV8 A;  2W13 A;  1CGL A;  1J7N A;  2A8H A;  5I4O A;  1GXD A;  2POJ A;  1PWP A;  1KUH A;  1ATL A;  3LJG A;  2OXZ A;  2ERP A;  1USN A;  2JT6 A;  1ZXV A;  2CKI A;  1BM6 A;  1HOV A;  1D5J A;  1ZTQ A;  2L0R A;  1XUD A;  1G49 A;  4WF6 A;  3LJZ A;  2OI0 A;  3BA0 A;  4XCT A;  2O3E A;  1R1H A;  3Q2H A;  1XUR A;  1K7Q A;  1GKD A;  3EDZ A;  2OZR A;  2DW1 A;  2Y6D A;  1Z3J A;  4H2E A;  1CXV A;  1G4K A;  1MMR A;  2FV9 A;  2MZE A;  3LIL A;  1RMZ A;  3DPF A;  2KRJ A;  3EDH A;  456C A;  1BIW A;  3DL1 A;  2MLR A;  5BPA A;  4I35 A;  1XFZ A;  1JIZ A;  2OXW A;  2W0D A;  3K7N A;  1OM8 A;  4R3V A;  1HTD A;  1Y0V A;  4IJO A;  4PKQ A;  4G0D A;  1ZVX A;  1Y93 A;  2AYK A;  1A86 A;  3AIG A;  4DPE A;  5L79 A;  1HFS A;  966C A;  3P24 A;  1SRP A;  3AYK A;  4XBH A;  1C8T A;  3LKA A;  3LQ0 A;  3B92 A;  1ROS A;  1SLM A;  4A3W A;  1IAE A;  4FXY P;  5BOT A;  1QJJ A;  2YB9 A;  1PWQ A;  2Y6C A;  5I2Z A;  2MZI A;  2ERO A;  1IAA A;  2X3C A;  3EWJ A;  4DD8 A;  5H8X A;  4PKW A;  1UMS A;  5I3M A;  4IN9 A;  1JK3 A;  1QUA A;  2OW9 A;  1G05 A;  3WV2 A;  1I76 A;  3KEJ A;  1GE5 A;  3HB2 P;  1IAB A;  3DSL A;  1B3D A;  4WKI A;  1PWU A;  1EB6 A;  2OY2 A;  4ILW D;  4FVL A;  1FBL A;  1HFC A;  1GE6 A;  2JIH A;  4FXQ A;  1XFU A;  1S4B P;  2YIG A;  4HX3 A;  1CIZ A;  2I47 A;  3WV1 A;  4GR8 A;  3Q2G A;  3KME A;  2WO8 A;  3EDG A;  5CXA A;  4GR3 A;  4GWN A;  3L0T A;  3HY9 A;  3LIK A;  4GR0 A;  3KRY A;  3K7L A;  1IAG A;  3ZUK A;  1SAT A;  1OM6 A;  4EFS A; 
#chains in the Genus database with same CATH topology
 4XM6 A;  1IAD A;  3KEK A;  1UMT A;  1GKC A;  1JAO A;  5CZM A;  3HYG A;  5L7F A;  1H71 P;  2DDF A;  1SU3 A;  4H30 A;  3F1A A;  1UTZ A;  5I0L A;  1XUC A;  3P1V A;  3HBV P;  3KEC A;  5JMY A;  2W14 A;  3EHY A;  4PKS A;  2OY4 A;  3MA2 A;  1YQY A;  5D3C A;  3F18 A;  4J4M A;  1XFX A;  2X7M A;  3U1R A;  1XAX A;  3F19 A;  1BSW A;  1Q3A A;  1MMB A;  2DDY A;  3L0V A;  1YCM A;  2K9C A;  4WKE A;  2OW1 A;  3DPE A;  4PKR A;  1QJI A;  3GBO A;  1QIA A;  1ZXC A;  2DW0 A;  3N2U A;  1BKC I;  4ZR5 A;  5I43 A;  3CKI A;  1WNI A;  3LUN A;  1QIB A;  4IUW A;  4PKT A;  1MNC A;  3HBU P;  2DW2 A;  3TVC A;  1KBC A;  3DWB A;  1ZS0 A;  1BQO A;  2TCL A;  4H3X A;  2ERQ A;  2USN A;  3OHO A;  1EAK A;  4JIJ A;  4L6T A;  2W12 A;  1KUI A;  1OMJ A;  1BKC A;  4H84 A;  1CGF A;  1R55 A;  1G9K A;  1HV5 A;  3B2Z A;  5D1T A;  3DTE A;  3TS4 A;  1Y8J A;  2JT5 A;  4PKV A;  1QIC A;  3KWV C;  3HDB A;  3USN A;  1D7X A;  3I7I A;  4JA1 A;  2W15 A;  2D1N A;  1D8M A;  3B8Z A;  1BKC E;  3ZVS A;  3F16 A;  4WZV A;  1C3I A;  1D8F A;  3F15 A;  1KUK A;  3KHI A;  3EHX A;  4A7B A;  1YOU A;  4GWM A;  1JJ9 A;  1GO7 P;  5D2B A;  1AF0 A;  4AUO A;  1BUV M;  5B5O A;  4JPA A;  2QPJ A;  1XFY A;  3DNG A;  1GO8 P;  3HDA P;  1R1I A;  1DTH A;  1C7K A;  4L19 A;  1KUF A;  1CQR A;  2JSD A;  1B8Y A;  5CUH A;  1EUB A;  2Z2D A;  1UEA A;  1KUG A;  3LJT A;  2SRT A;  1XFW A;  1SLN A;  1OM7 A;  1YP1 A;  3TT4 A;  5I12 A;  3LK8 A;  4L63 A;  3TSK A;  2CLT A;  2OVZ A;  4GF1 A;  2E2D A;  1ZP5 A;  2X3B A;  3LGP A;  3DTI A;  2D1O A;  3O64 A;  3LE9 A;  2J0T A;  4H1Q A;  2V4B A;  3HY7 A;  1JIW P;  1OS2 A;  2MZH A;  3UVC A;  1ND1 A;  4AXQ A;  2OW2 A;  1MMP A;  1IAC A;  3LEA A;  1JAQ A;  1K7I A;  3E8R A;  4AIG A;  2HU6 A;  3ELM A;  1R1J A;  1OZ9 A;  1K7G A;  4ON1 A;  2JNP A;  5D1S A;  1PWW A;  3LUM A;  3LQB A;  2XS4 A;  1XFV A;  1AYK A;  1AKL A;  2AIG P;  4H82 A;  2N8R A;  1GE7 A;  1SMP A;  4WK7 A;  2E3X A;  1PWV A;  2FV5 A;  1RM8 A;  4H76 A;  2OXU A;  1I1I P;  3G5C A;  1BZS A;  3F17 A;  4QKZ A;  4DF9 A;  1FLS A;  2OW0 A;  830C A;  1I73 A;  3WV3 A;  1MMQ A;  4CTH A;  4GQL A;  1CK7 A;  1L6J A;  4JQG A;  1FM1 A;  1DMT A;  1OS9 A;  2MLS A;  4XM7 A;  3RTT A;  2K2G A;  2OVX A;  3KMC A;  4L7A A;  1O0T A;  4I03 A;  4XM8 A;  4JP4 A;  3N2V A;  3O2X A;  4H49 A;  5BOY A;  2J83 A;  1OO9 A;  3RTS A;  1G12 A;  3I7G A;  1BQQ M;  4PKU A;  3EDI A;  1AST A;  1XM5 A;  2WO9 A;  4HMA A;  2RJP A;  2PJT A;  2RJQ A;  2WOA A;  3VI1 A;  5D1U A;  2O36 A;  3ZXH A;  3LMC A;  1JKY A;  1JH1 A;  2XS3 A;  3LIR A;  1KAP P;  1JAN A;  5B5P A;  3SHI A;  5LAB A;  3VTG A;  1UTT A;  1BUD A;  1O0Q A;  3V96 B;  4AYK A;  1A85 A;  1R54 A;  3OHL A;  4FU4 A;  4G9L A;  1JAP A;  3NX7 A;  1CAQ A;  1HY7 A;  1CGE A;  3G42 A;  3AYU A;  2X3A A;  5D7W A;  4Q1L A;  4GUY A;  4DV8 A;  2W13 A;  1CGL A;  1J7N A;  2A8H A;  5I4O A;  1GXD A;  2POJ A;  1PWP A;  1KUH A;  1ATL A;  3LJG A;  2OXZ A;  2ERP A;  1USN A;  2JT6 A;  1ZXV A;  2CKI A;  1BM6 A;  1HOV A;  1D5J A;  1ZTQ A;  2L0R A;  1XUD A;  1G49 A;  4WF6 A;  3LJZ A;  2OI0 A;  3BA0 A;  4XCT A;  2O3E A;  1R1H A;  3Q2H A;  1XUR A;  1K7Q A;  1GKD A;  3EDZ A;  2OZR A;  2DW1 A;  2Y6D A;  1Z3J A;  4H2E A;  1CXV A;  1G4K A;  1MMR A;  2FV9 A;  2MZE A;  3LIL A;  1RMZ A;  3DPF A;  2KRJ A;  1TVI A;  3EDH A;  456C A;  1BIW A;  3DL1 A;  2MLR A;  5BPA A;  4I35 A;  1XFZ A;  1JIZ A;  2OXW A;  2W0D A;  3K7N A;  1OM8 A;  4R3V A;  1HTD A;  1Y0V A;  4IJO A;  4PKQ A;  4G0D A;  1ZVX A;  1Y93 A;  2AYK A;  1A86 A;  3AIG A;  4DPE A;  5L79 A;  1HFS A;  966C A;  3P24 A;  1SRP A;  3AYK A;  4XBH A;  1C8T A;  3LKA A;  3LQ0 A;  3B92 A;  1ROS A;  1SLM A;  4A3W A;  1IAE A;  4FXY P;  5BOT A;  1QJJ A;  2YB9 A;  1PWQ A;  2Y6C A;  5I2Z A;  2MZI A;  2ERO A;  1IAA A;  2X3C A;  3EWJ A;  4DD8 A;  5H8X A;  4PKW A;  1UMS A;  5I3M A;  4IN9 A;  1JK3 A;  1QUA A;  3DTK A;  2OW9 A;  1G05 A;  3WV2 A;  1I76 A;  3KEJ A;  1GE5 A;  3HB2 P;  1IAB A;  3DSL A;  1B3D A;  4WKI A;  1PWU A;  1EB6 A;  2OY2 A;  4ILW D;  4FVL A;  1FBL A;  1HFC A;  1GE6 A;  2JIH A;  4FXQ A;  1XFU A;  1S4B P;  2YIG A;  4HX3 A;  1CIZ A;  2I47 A;  3WV1 A;  2YUF A;  4GR8 A;  3Q2G A;  3KME A;  2WO8 A;  3EDG A;  5CXA A;  4GR3 A;  4GWN A;  3L0T A;  3HY9 A;  3LIK A;  4GR0 A;  3KRY A;  3K7L A;  1IAG A;  3ZUK A;  1SAT A;  1OM6 A;  4EFS A; 
#chains in the Genus database with same CATH homology
 4XM6 A;  1IAD A;  3KEK A;  1UMT A;  1GKC A;  1JAO A;  5CZM A;  3HYG A;  5L7F A;  1H71 P;  2DDF A;  1SU3 A;  4H30 A;  3F1A A;  1UTZ A;  5I0L A;  1XUC A;  3P1V A;  3HBV P;  3KEC A;  5JMY A;  2W14 A;  3EHY A;  4PKS A;  2OY4 A;  3MA2 A;  1YQY A;  5D3C A;  3F18 A;  4J4M A;  1XFX A;  2X7M A;  3U1R A;  3F19 A;  1BSW A;  1Q3A A;  1MMB A;  2DDY A;  3L0V A;  1YCM A;  2K9C A;  4WKE A;  2OW1 A;  3DPE A;  4PKR A;  1QJI A;  3GBO A;  1QIA A;  1ZXC A;  2DW0 A;  3N2U A;  1BKC I;  4ZR5 A;  5I43 A;  3CKI A;  1WNI A;  3LUN A;  1QIB A;  4IUW A;  4PKT A;  1MNC A;  3HBU P;  2DW2 A;  3TVC A;  1KBC A;  3DWB A;  1ZS0 A;  1BQO A;  2TCL A;  4H3X A;  2ERQ A;  2USN A;  3OHO A;  1EAK A;  4JIJ A;  4L6T A;  2W12 A;  1KUI A;  1OMJ A;  1BKC A;  4H84 A;  1CGF A;  1R55 A;  1G9K A;  1HV5 A;  3B2Z A;  5D1T A;  3DTE A;  3TS4 A;  1Y8J A;  2JT5 A;  4PKV A;  1QIC A;  3KWV C;  3HDB A;  3USN A;  1D7X A;  3I7I A;  4JA1 A;  2W15 A;  2D1N A;  1D8M A;  3B8Z A;  1BKC E;  3ZVS A;  3F16 A;  4WZV A;  1C3I A;  1D8F A;  3F15 A;  1KUK A;  3KHI A;  3EHX A;  4A7B A;  1YOU A;  4GWM A;  1JJ9 A;  1GO7 P;  5D2B A;  1AF0 A;  4AUO A;  1BUV M;  5B5O A;  4JPA A;  2QPJ A;  1XFY A;  3DNG A;  1GO8 P;  3HDA P;  1R1I A;  1DTH A;  1C7K A;  4L19 A;  1KUF A;  1CQR A;  2JSD A;  1B8Y A;  5CUH A;  1EUB A;  2Z2D A;  1UEA A;  1KUG A;  3LJT A;  2SRT A;  1XFW A;  1SLN A;  1OM7 A;  1YP1 A;  3TT4 A;  5I12 A;  3LK8 A;  4L63 A;  3TSK A;  2CLT A;  2OVZ A;  4GF1 A;  2E2D A;  1ZP5 A;  2X3B A;  3LGP A;  3DTI A;  2D1O A;  3O64 A;  3LE9 A;  2J0T A;  4H1Q A;  2V4B A;  3HY7 A;  1JIW P;  1OS2 A;  2MZH A;  3UVC A;  1ND1 A;  4AXQ A;  2OW2 A;  1MMP A;  1IAC A;  3LEA A;  1JAQ A;  1K7I A;  3E8R A;  4AIG A;  2HU6 A;  3ELM A;  1R1J A;  1K7G A;  4ON1 A;  2JNP A;  5D1S A;  1PWW A;  3LUM A;  3LQB A;  2XS4 A;  1XFV A;  1AYK A;  1AKL A;  2AIG P;  4H82 A;  2N8R A;  1GE7 A;  1SMP A;  4WK7 A;  2E3X A;  1PWV A;  2FV5 A;  1RM8 A;  4H76 A;  2OXU A;  1I1I P;  3G5C A;  1BZS A;  3F17 A;  4QKZ A;  4DF9 A;  1FLS A;  2OW0 A;  830C A;  1I73 A;  3WV3 A;  1MMQ A;  4CTH A;  4GQL A;  1CK7 A;  1L6J A;  4JQG A;  1FM1 A;  1DMT A;  1OS9 A;  2MLS A;  4XM7 A;  3RTT A;  2K2G A;  2OVX A;  3KMC A;  4L7A A;  1O0T A;  4I03 A;  4XM8 A;  4JP4 A;  3N2V A;  3O2X A;  4H49 A;  5BOY A;  2J83 A;  1OO9 A;  3RTS A;  1G12 A;  3I7G A;  1BQQ M;  4PKU A;  3EDI A;  1AST A;  4HMA A;  2WO9 A;  2RJP A;  2PJT A;  2RJQ A;  2WOA A;  3VI1 A;  5D1U A;  2O36 A;  3ZXH A;  3LMC A;  1JKY A;  1JH1 A;  2XS3 A;  3LIR A;  1KAP P;  1JAN A;  5B5P A;  3SHI A;  5LAB A;  3VTG A;  1UTT A;  1BUD A;  1O0Q A;  3V96 B;  4AYK A;  1A85 A;  1R54 A;  3OHL A;  4FU4 A;  4G9L A;  1JAP A;  3NX7 A;  1CAQ A;  1HY7 A;  1CGE A;  3G42 A;  3AYU A;  2X3A A;  5D7W A;  4Q1L A;  4GUY A;  4DV8 A;  2W13 A;  1CGL A;  1J7N A;  2A8H A;  5I4O A;  1GXD A;  2POJ A;  1PWP A;  1KUH A;  1ATL A;  3LJG A;  2OXZ A;  2ERP A;  1USN A;  2JT6 A;  1ZXV A;  2CKI A;  1BM6 A;  1HOV A;  1D5J A;  1ZTQ A;  2L0R A;  1XUD A;  1G49 A;  4WF6 A;  3LJZ A;  2OI0 A;  3BA0 A;  4XCT A;  2O3E A;  1R1H A;  3Q2H A;  1XUR A;  1K7Q A;  1GKD A;  3EDZ A;  2OZR A;  2DW1 A;  2Y6D A;  1Z3J A;  4H2E A;  1CXV A;  1G4K A;  1MMR A;  2FV9 A;  2MZE A;  3LIL A;  1RMZ A;  3DPF A;  2KRJ A;  3EDH A;  456C A;  1BIW A;  3DL1 A;  2MLR A;  5BPA A;  4I35 A;  1XFZ A;  1JIZ A;  2OXW A;  2W0D A;  3K7N A;  1OM8 A;  4R3V A;  1HTD A;  1Y0V A;  4IJO A;  4PKQ A;  4G0D A;  1ZVX A;  1Y93 A;  2AYK A;  1A86 A;  3AIG A;  4DPE A;  5L79 A;  1HFS A;  966C A;  3P24 A;  1SRP A;  3AYK A;  4XBH A;  1C8T A;  3LKA A;  3LQ0 A;  3B92 A;  1ROS A;  1SLM A;  4A3W A;  1IAE A;  4FXY P;  5BOT A;  1QJJ A;  2YB9 A;  1PWQ A;  2Y6C A;  5I2Z A;  2MZI A;  2ERO A;  1IAA A;  2X3C A;  3EWJ A;  4DD8 A;  5H8X A;  4PKW A;  1UMS A;  5I3M A;  4IN9 A;  1JK3 A;  1QUA A;  3DTK A;  2OW9 A;  1G05 A;  3WV2 A;  1I76 A;  3KEJ A;  1GE5 A;  3HB2 P;  1IAB A;  3DSL A;  1B3D A;  4WKI A;  1PWU A;  1EB6 A;  2OY2 A;  4ILW D;  4FVL A;  1FBL A;  1HFC A;  1GE6 A;  2JIH A;  4FXQ A;  1XFU A;  1S4B P;  2YIG A;  4HX3 A;  1CIZ A;  2I47 A;  3WV1 A;  2YUF A;  4GR8 A;  3Q2G A;  3KME A;  2WO8 A;  3EDG A;  5CXA A;  4GR3 A;  4GWN A;  3L0T A;  3HY9 A;  3LIK A;  4GR0 A;  3KRY A;  3K7L A;  1IAG A;  3ZUK A;  1SAT A;  1OM6 A;  4EFS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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