4QKZA

X-ray structure of the catalytic domain of mmp-8 with the inhibitor ml115
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
163
structure length
163
Chain Sequence
MLTPGNPKWERTNLTYRIRNYTPQLSEAEVERAIKDAFELWSVASPLIFTRISQGEADINIAFYQRDHGDNSPFDGPNGILAHAFQPGQGIGGDAHFDAEETWTNTSANYNLFLVAAHEFGHSLGLAHSSDPGALMYPNYAFRETSNYSLPQDDIDGIQAIYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray structure of the complex of the catalytic domain of MMP-8 and a bis-phosphonate inhibitor (ML115)
rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Neutrophil collagenase
total genus 50
structure length 163
sequence length 163
ec nomenclature ec 3.4.24.34: Neutrophil collagenase.
pdb deposition date 2014-06-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 4qkzA00
2X3AA 4HMAA 3B2ZA 1XFWA 1G12A 4QKZA 3L0TA 3HY7A 2OW0A 3DNGA 1MMPA 1MMQA 4IN9A 4GR0A 5BOTA 5BOYA 1KUFA 5L79A 1BQOA 3DPFA 2W14A 1XFYA 1YOUA 2OVZA 3F18A 3KEJA 3VI1A 2J83A 1IAGA 1XURA 1YCMA 4H3XA 5L7FA 3KEKA 4ILWD 4HX3A 5I3MA 4ON1A 3WV1A 3AIGA 2W15A 1ND1A 4WK7A 1JANA 1I1IP 5LABA 3G5CA 5I0LA 3MA2A 5CZMA 1G4KA 1HFCA 3SHIA 1D7XA 1GKCA 3ELMA 3DWBA 1EAKA 1CIZA 3KRYA 3N2VA 3LQBA 1K7GA 3LJGA 1BUDA 4FU4A 3WV2A 1SMPA 4JA1A 4I35A 3I7GA 3LUNA 4WKEA 5D2BA 2W13A 1UTZA 3LKAA 1KAPP 1Y8JA 1HY7A 1C3IA 1K7QA 2JT6A 1J7NA 2DW0A 2XS3A 1GE5A 1CGEA 2AIGP 2O36A 5CUHA 4GQLA 2Y6DA 4JPAA 2OVXA 4R3VA 1KUHA 3HDBA 4H1QA 4PKTA 4GWNA 3Q2HA 1HFSA 1YQYA 3F15A 4I03A 1O0QA 1GXDA 1XUDA 5JMYA 1OM7A 1OO9A 1YP1A 2QPJA 1JAPA 4L63A 2XS4A 1JK3A 3LIKA 3LUMA 1BSWA 2OXUA 5I43A 3DPEA 1QIBA 1KBCA 3Q2GA 2V4BA 4Q1LA 1PWVA 1MNCA 2OW2A 3F19A 3AYUA 1ZXCA 4CTHA 3U1RA 2OW1A 1AF0A 2I47A 1SATA 2TCLA 1IACA 1GKDA 1BIWA 2SRTA 1R1JA 1CGLA 3HBUP 3USNA 3EWJA 4XM7A 1HV5A 1QUAA 5D1UA 1C8TA 2MLRA 4FXQA 1MMRA 3P24A 1UTTA 2AYKA 3KECA 3ZVSA 1ZTQA 3OHOA 2N8RA 3N2UA 3O64A 4XM6A 5D3CA 3TS4A 1XFZA 1FM1A 2X3BA 1RM8A 1HOVA 1D5JA 1KUIA 1Z3JA 1ZVXA 1JAOA 1KUGA 1CGFA 1R1IA 1JIWP 2DDFA 4GWMA 1SRPA 3LILA 3LQ0A 1SLNA 3KWVC 1XFXA 2JSDA 2DDYA 3HY9A 3TT4A 3F17A 4H84A 2RJPA 1PWWA 3P1VA 2J0TA 2HU6A 1JKYA 456CA 1R54A 5I2ZA 3RTSA 1BZSA 3EHYA 3DL1A 4G0DA 1OMJA 1WNIA 1FBLA 1UEAA 3LIRA 4GUYA 3E8RA 830CA 1XUCA 3LJTA 4FXYP 2FV5A 3HB2P 4GF1A 1FLSA 1A86A 1G49A 1B3DA 1IADA 1I76A 1AKLA 1C7KA 2W0DA 1OM6A 5D1TA 3AYKA 3HBVP 3K7NA 3RTTA 4L6TA 5CXAA 3LMCA 2X7MA 1PWQA 5H8XA 4PKUA 4XM8A 1QIAA 1GE7A 1GO8P 1BKCI 1ASTA 1IAAA 2OXZA 1SU3A 1O0TA 1R55A 1JH1A 1XFVA 1XFUA 2DW1A 1IAEA 1RMZA 2OW9A 5BPAA 1Q3AA 3NX7A 2YB9A 4WF6A 1AYKA 1CXVA 1QJIA 4PKSA 3TVCA 4L19A 1KUKA 2OI0A 4WKIA 4DD8A 1OS9A 2W12A 1B8YA 1IABA 2WO8A 1R1HA 2D1OA 3L0VA 3DSLA 3WV3A 2D1NA 3TSKA 5I4OA 5D7WA 2L0RA 4FVLA 3KMCA 2JT5A 1CAQA 1BM6A 2MLSA 3HYGA 1OM8A 4XCTA 1HTDA 5I12A 3F16A 3KMEA 4H49A 2CLTA 4IJOA 4PKWA 5B5PA 1JJ9A 1D8FA 1S4BP 3EDGA 1ROSA 3OHLA 1ZP5A 3EHXA 2WO9A 1GE6A 4DV8A 1BKCE 1QJJA 2JIHA 1PWPA 3F1AA 3G42A 3EDIA 2USNA 1BUVM 1JAQA 4WZVA 2RJQA 4A3WA 1A85A 4PKVA 1USNA 4GR3A 4AXQA 3V96B 1Y93A 1D8MA 1OS2A 1EUBA 1UMSA 2X3CA 2CKIA 2YIGA 1G9KA 2O3EA 4H76A 3ZUKA 3VTGA 2OZRA 2OY2A 4A7BA 1CQRA 1EB6A 2E3XA 1UMTA 1ZXVA 1QICA 1CK7A 2Z2DA 4H30A 4H82A 3LEAA 1DTHA 2MZIA 1I73A 1G05A 1BQQM 3LE9A 3O2XA 1ATLA 2Y6CA 3B92A 3K7LA 4DPEA 1MMBA 2E2DA 2WOAA 4PKRA 3BA0A 4JP4A 4JQGA 4AYKA 966CA 3CKIA 4EFSA 2DW2A 2EROA 5B5OA 1Y0VA 1L6JA 3LK8A 3UVCA 3GBOA 2OY4A 1H71P 4J4MA 1JIZA 4DF9A 3EDZA 1GO7P 3B8ZA 3HDAP 4ZR5A 4XBHA 1BKCA 2MZEA 1ZS0A 4H2EA 2MZHA 3I7IA 2A8HA 4AUOA 3EDHA 4GR8A 2ERQA 3ZXHA 1PWUA 2K2GA 3KHIA 2K9CA 3LGPA 3LJZA 4PKQA 2KRJA 1DMTA 2FV9A 2POJA 2PJTA 4AIGA 4JIJA 5D1SA 4IUWA 4G9LA 1SLMA 1K7IA 2JNPA 2ERPA 2OXWA
chains in the Genus database with same CATH superfamily
2X3AA 4HMAA 3B2ZA 1XFWA 1G12A 4QKZA 3L0TA 3HY7A 2OW0A 3DNGA 1MMPA 1MMQA 4IN9A 4GR0A 5BOTA 5BOYA 1KUFA 5L79A 1BQOA 3DPFA 2W14A 1XFYA 1YOUA 2OVZA 3F18A 3KEJA 3VI1A 2J83A 1IAGA 1XURA 1YCMA 4H3XA 5L7FA 3KEKA 4ILWD 4HX3A 5I3MA 4ON1A 3WV1A 3AIGA 2W15A 4L7AA 1ND1A 4WK7A 1JANA 1I1IP 5LABA 3G5CA 5I0LA 3MA2A 5CZMA 1G4KA 1HFCA 3SHIA 1D7XA 1GKCA 3ELMA 3DWBA 1EAKA 1CIZA 3KRYA 3N2VA 3LQBA 1K7GA 3LJGA 1BUDA 4FU4A 3WV2A 1SMPA 4JA1A 4I35A 3I7GA 3LUNA 4WKEA 5D2BA 2W13A 1UTZA 3LKAA 1KAPP 1Y8JA 1HY7A 1C3IA 1K7QA 3DTEA 2JT6A 1J7NA 2DW0A 2XS3A 1GE5A 1CGEA 2AIGP 2O36A 5CUHA 4GQLA 2Y6DA 4JPAA 2OVXA 4R3VA 3DTIA 1KUHA 3HDBA 4H1QA 4PKTA 4GWNA 3Q2HA 1HFSA 1YQYA 3F15A 4I03A 1O0QA 1GXDA 1XUDA 5JMYA 1OM7A 1OO9A 1YP1A 2QPJA 1JAPA 4L63A 2XS4A 1JK3A 3LIKA 3LUMA 1BSWA 2OXUA 5I43A 3DPEA 1QIBA 1KBCA 3Q2GA 2V4BA 3DTKA 4Q1LA 1PWVA 1MNCA 2OW2A 3F19A 3AYUA 1ZXCA 4CTHA 3U1RA 2OW1A 1AF0A 2I47A 1SATA 2TCLA 1IACA 1GKDA 1BIWA 2SRTA 1R1JA 1CGLA 3HBUP 3USNA 3EWJA 4XM7A 1HV5A 1QUAA 5D1UA 1C8TA 2MLRA 4FXQA 1MMRA 3P24A 1UTTA 2AYKA 3KECA 3ZVSA 1ZTQA 3OHOA 2N8RA 3N2UA 3O64A 4XM6A 5D3CA 3TS4A 1XFZA 1FM1A 2X3BA 1RM8A 1HOVA 1D5JA 1KUIA 1Z3JA 1ZVXA 1JAOA 1KUGA 1CGFA 1R1IA 1JIWP 2DDFA 4GWMA 1SRPA 3LILA 1XM5A 3LQ0A 1SLNA 3KWVC 1XFXA 2JSDA 2DDYA 1TVIA 3HY9A 3TT4A 3F17A 4H84A 2RJPA 1PWWA 3P1VA 2J0TA 2HU6A 1JKYA 456CA 1R54A 5I2ZA 3RTSA 1BZSA 3EHYA 3DL1A 4G0DA 1OMJA 1WNIA 1FBLA 1UEAA 3LIRA 4GUYA 3E8RA 830CA 1XUCA 3LJTA 4FXYP 2FV5A 3HB2P 4GF1A 1FLSA 1A86A 1G49A 1B3DA 1IADA 1I76A 1AKLA 1C7KA 2W0DA 1OM6A 5D1TA 3AYKA 3HBVP 3K7NA 1XAXA 3RTTA 4L6TA 5CXAA 3LMCA 2X7MA 1PWQA 5H8XA 4PKUA 4XM8A 1QIAA 1GE7A 1GO8P 1BKCI 1ASTA 1IAAA 2OXZA 1SU3A 1O0TA 1R55A 1JH1A 1XFVA 1XFUA 2DW1A 1IAEA 1RMZA 2OW9A 5BPAA 1Q3AA 3NX7A 2YB9A 4WF6A 1AYKA 1CXVA 1QJIA 4PKSA 3TVCA 2YUFA 4L19A 1KUKA 2OI0A 4WKIA 4DD8A 1OS9A 2W12A 1B8YA 1IABA 2WO8A 1R1HA 2D1OA 3L0VA 3DSLA 3WV3A 2D1NA 3TSKA 5I4OA 5D7WA 2L0RA 4FVLA 3KMCA 2JT5A 1CAQA 1BM6A 2MLSA 3HYGA 1OM8A 4XCTA 1HTDA 5I12A 3F16A 3KMEA 4H49A 2CLTA 4IJOA 4PKWA 5B5PA 1JJ9A 1D8FA 1S4BP 3EDGA 1ROSA 3OHLA 1ZP5A 3EHXA 2WO9A 1GE6A 4DV8A 1BKCE 1QJJA 2JIHA 1PWPA 3F1AA 3G42A 3EDIA 2USNA 1BUVM 1JAQA 4WZVA 2RJQA 4A3WA 1A85A 4PKVA 1USNA 4GR3A 4AXQA 3V96B 1Y93A 1D8MA 1OS2A 1EUBA 1UMSA 2X3CA 2CKIA 2YIGA 1G9KA 2O3EA 4H76A 3ZUKA 3VTGA 2OZRA 2OY2A 4A7BA 1CQRA 1EB6A 2E3XA 1UMTA 1ZXVA 1QICA 1CK7A 2Z2DA 4H30A 4H82A 3LEAA 1DTHA 2MZIA 1I73A 1G05A 1BQQM 3LE9A 3O2XA 1ATLA 2Y6CA 3B92A 3K7LA 4DPEA 1MMBA 2E2DA 2WOAA 4PKRA 3BA0A 4JP4A 4JQGA 4AYKA 966CA 3CKIA 4EFSA 2DW2A 2EROA 5B5OA 1Y0VA 1L6JA 3LK8A 3UVCA 3GBOA 2OY4A 1H71P 4J4MA 1JIZA 4DF9A 3EDZA 1GO7P 3B8ZA 3HDAP 4ZR5A 4XBHA 1BKCA 2MZEA 1ZS0A 4H2EA 2MZHA 3I7IA 2A8HA 4AUOA 3EDHA 4GR8A 2ERQA 3ZXHA 1PWUA 2K2GA 3KHIA 2K9CA 3LGPA 3LJZA 1OZ9A 4PKQA 2KRJA 1DMTA 2FV9A 2POJA 2PJTA 4AIGA 4JIJA 5D1SA 4IUWA 4G9LA 1SLMA 1K7IA 2JNPA 2ERPA 2OXWA
chains in the Genus database with same CATH topology
2X3AA 4HMAA 3B2ZA 1XFWA 1G12A 4QKZA 3L0TA 3HY7A 2OW0A 3DNGA 1MMPA 1MMQA 4IN9A 4GR0A 5BOTA 5BOYA 1KUFA 5L79A 1BQOA 3DPFA 2W14A 1XFYA 1YOUA 2OVZA 3F18A 3KEJA 3VI1A 2J83A 1IAGA 1XURA 1YCMA 4H3XA 5L7FA 3KEKA 4ILWD 4HX3A 5I3MA 4ON1A 3WV1A 3AIGA 2W15A 4L7AA 1ND1A 4WK7A 1JANA 1I1IP 5LABA 3G5CA 5I0LA 3MA2A 5CZMA 1G4KA 1HFCA 3SHIA 1D7XA 1GKCA 3ELMA 3DWBA 1EAKA 1CIZA 3KRYA 3N2VA 3LQBA 1K7GA 3LJGA 1BUDA 4FU4A 3WV2A 1SMPA 4JA1A 4I35A 3I7GA 3LUNA 4WKEA 5D2BA 2W13A 1UTZA 3LKAA 1KAPP 1Y8JA 1HY7A 1C3IA 1K7QA 3DTEA 2JT6A 1J7NA 2DW0A 2XS3A 1GE5A 1CGEA 2AIGP 2O36A 5CUHA 4GQLA 2Y6DA 4JPAA 2OVXA 4R3VA 3DTIA 1KUHA 3HDBA 4H1QA 4PKTA 4GWNA 3Q2HA 1HFSA 1YQYA 3F15A 4I03A 1O0QA 1GXDA 1XUDA 5JMYA 1OM7A 1OO9A 1YP1A 2QPJA 1JAPA 4L63A 2XS4A 1JK3A 3LIKA 3LUMA 1BSWA 2OXUA 5I43A 3DPEA 1QIBA 1KBCA 3Q2GA 2V4BA 3DTKA 4Q1LA 1PWVA 1MNCA 2OW2A 3F19A 3AYUA 1ZXCA 4CTHA 3U1RA 2OW1A 1AF0A 2I47A 1SATA 2TCLA 1IACA 1GKDA 1BIWA 2SRTA 1R1JA 1CGLA 3HBUP 3USNA 3EWJA 4XM7A 1HV5A 1QUAA 5D1UA 1C8TA 2MLRA 4FXQA 1MMRA 3P24A 1UTTA 2AYKA 3KECA 3ZVSA 1ZTQA 3OHOA 2N8RA 3N2UA 3O64A 4XM6A 5D3CA 3TS4A 1XFZA 1FM1A 2X3BA 1RM8A 1HOVA 1D5JA 1KUIA 1Z3JA 1ZVXA 1JAOA 1KUGA 1CGFA 1R1IA 1JIWP 2DDFA 4GWMA 1SRPA 3LILA 3LQ0A 1SLNA 3KWVC 1XFXA 2JSDA 2DDYA 3HY9A 3TT4A 3F17A 4H84A 2RJPA 1PWWA 3P1VA 2J0TA 2HU6A 1JKYA 456CA 1R54A 5I2ZA 3RTSA 1BZSA 3EHYA 3DL1A 4G0DA 1OMJA 1WNIA 1FBLA 1UEAA 3LIRA 4GUYA 3E8RA 830CA 1XUCA 3LJTA 4FXYP 2FV5A 3HB2P 4GF1A 1FLSA 1A86A 1G49A 1B3DA 1IADA 1I76A 1AKLA 1C7KA 2W0DA 1OM6A 5D1TA 3AYKA 3HBVP 3K7NA 3RTTA 4L6TA 5CXAA 3LMCA 2X7MA 1PWQA 5H8XA 4PKUA 4XM8A 1QIAA 1GE7A 1GO8P 1BKCI 1ASTA 1IAAA 2OXZA 1SU3A 1O0TA 1R55A 1JH1A 1XFVA 1XFUA 2DW1A 1IAEA 1RMZA 2OW9A 5BPAA 1Q3AA 3NX7A 2YB9A 4WF6A 1AYKA 1CXVA 1QJIA 4PKSA 3TVCA 2YUFA 4L19A 1KUKA 2OI0A 4WKIA 4DD8A 1OS9A 2W12A 1B8YA 1IABA 2WO8A 1R1HA 2D1OA 3L0VA 3DSLA 3WV3A 2D1NA 3TSKA 5I4OA 5D7WA 2L0RA 4FVLA 3KMCA 2JT5A 1CAQA 1BM6A 2MLSA 3HYGA 1OM8A 4XCTA 1HTDA 5I12A 3F16A 3KMEA 4H49A 2CLTA 4IJOA 4PKWA 5B5PA 1JJ9A 1D8FA 1S4BP 3EDGA 1ROSA 3OHLA 1ZP5A 3EHXA 2WO9A 1GE6A 4DV8A 1BKCE 1QJJA 2JIHA 1PWPA 3F1AA 3G42A 3EDIA 2USNA 1BUVM 1JAQA 4WZVA 2RJQA 4A3WA 1A85A 4PKVA 1USNA 4GR3A 4AXQA 3V96B 1Y93A 1D8MA 1OS2A 1EUBA 1UMSA 2X3CA 2CKIA 2YIGA 1G9KA 2O3EA 4H76A 3ZUKA 3VTGA 2OZRA 2OY2A 4A7BA 1CQRA 1EB6A 2E3XA 1UMTA 1ZXVA 1QICA 1CK7A 2Z2DA 4H30A 4H82A 3LEAA 1DTHA 2MZIA 1I73A 1G05A 1BQQM 3LE9A 3O2XA 1ATLA 2Y6CA 3B92A 3K7LA 4DPEA 1MMBA 2E2DA 2WOAA 4PKRA 3BA0A 4JP4A 4JQGA 4AYKA 966CA 3CKIA 4EFSA 2DW2A 2EROA 5B5OA 1Y0VA 1L6JA 3LK8A 3UVCA 3GBOA 2OY4A 1H71P 4J4MA 1JIZA 4DF9A 3EDZA 1GO7P 3B8ZA 3HDAP 4ZR5A 4XBHA 1BKCA 2MZEA 1ZS0A 4H2EA 2MZHA 3I7IA 2A8HA 4AUOA 3EDHA 4GR8A 2ERQA 3ZXHA 1PWUA 2K2GA 3KHIA 2K9CA 3LGPA 3LJZA 4PKQA 2KRJA 1DMTA 2FV9A 2POJA 2PJTA 4AIGA 4JIJA 5D1SA 4IUWA 4G9LA 1SLMA 1K7IA 2JNPA 2ERPA 2OXWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2X3A A;  4HMA A;  3B2Z A;  1XFW A;  1G12 A;  4QKZ A;  3L0T A;  3HY7 A;  2OW0 A;  3DNG A;  1MMP A;  1MMQ A;  4IN9 A;  4GR0 A;  5BOT A;  5BOY A;  1KUF A;  5L79 A;  1BQO A;  3DPF A;  2W14 A;  1XFY A;  1YOU A;  2OVZ A;  3F18 A;  3KEJ A;  3VI1 A;  2J83 A;  1IAG A;  1XUR A;  1YCM A;  4H3X A;  5L7F A;  3KEK A;  4ILW D;  4HX3 A;  5I3M A;  4ON1 A;  3WV1 A;  3AIG A;  2W15 A;  1ND1 A;  4WK7 A;  1JAN A;  1I1I P;  5LAB A;  3G5C A;  5I0L A;  3MA2 A;  5CZM A;  1G4K A;  1HFC A;  3SHI A;  1D7X A;  1GKC A;  3ELM A;  3DWB A;  1EAK A;  1CIZ A;  3KRY A;  3N2V A;  3LQB A;  1K7G A;  3LJG A;  1BUD A;  4FU4 A;  3WV2 A;  1SMP A;  4JA1 A;  4I35 A;  3I7G A;  3LUN A;  4WKE A;  5D2B A;  2W13 A;  1UTZ A;  3LKA A;  1KAP P;  1Y8J A;  1HY7 A;  1C3I A;  1K7Q A;  2JT6 A;  1J7N A;  2DW0 A;  2XS3 A;  1GE5 A;  1CGE A;  2AIG P;  2O36 A;  5CUH A;  4GQL A;  2Y6D A;  4JPA A;  2OVX A;  4R3V A;  1KUH A;  3HDB A;  4H1Q A;  4PKT A;  4GWN A;  3Q2H A;  1HFS A;  1YQY A;  3F15 A;  4I03 A;  1O0Q A;  1GXD A;  1XUD A;  5JMY A;  1OM7 A;  1OO9 A;  1YP1 A;  2QPJ A;  1JAP A;  4L63 A;  2XS4 A;  1JK3 A;  3LIK A;  3LUM A;  1BSW A;  2OXU A;  5I43 A;  3DPE A;  1QIB A;  1KBC A;  3Q2G A;  2V4B A;  4Q1L A;  1PWV A;  1MNC A;  2OW2 A;  3F19 A;  3AYU A;  1ZXC A;  4CTH A;  3U1R A;  2OW1 A;  1AF0 A;  2I47 A;  1SAT A;  2TCL A;  1IAC A;  1GKD A;  1BIW A;  2SRT A;  1R1J A;  1CGL A;  3HBU P;  3USN A;  3EWJ A;  4XM7 A;  1HV5 A;  1QUA A;  5D1U A;  1C8T A;  2MLR A;  4FXQ A;  1MMR A;  3P24 A;  1UTT A;  2AYK A;  3KEC A;  3ZVS A;  1ZTQ A;  3OHO A;  2N8R A;  3N2U A;  3O64 A;  4XM6 A;  5D3C A;  3TS4 A;  1XFZ A;  1FM1 A;  2X3B A;  1RM8 A;  1HOV A;  1D5J A;  1KUI A;  1Z3J A;  1ZVX A;  1JAO A;  1KUG A;  1CGF A;  1R1I A;  1JIW P;  2DDF A;  4GWM A;  1SRP A;  3LIL A;  3LQ0 A;  1SLN A;  3KWV C;  1XFX A;  2JSD A;  2DDY A;  3HY9 A;  3TT4 A;  3F17 A;  4H84 A;  2RJP A;  1PWW A;  3P1V A;  2J0T A;  2HU6 A;  1JKY A;  456C A;  1R54 A;  5I2Z A;  3RTS A;  1BZS A;  3EHY A;  3DL1 A;  4G0D A;  1OMJ A;  1WNI A;  1FBL A;  1UEA A;  3LIR A;  4GUY A;  3E8R A;  830C A;  1XUC A;  3LJT A;  4FXY P;  2FV5 A;  3HB2 P;  4GF1 A;  1FLS A;  1A86 A;  1G49 A;  1B3D A;  1IAD A;  1I76 A;  1AKL A;  1C7K A;  2W0D A;  1OM6 A;  5D1T A;  3AYK A;  3HBV P;  3K7N A;  3RTT A;  4L6T A;  5CXA A;  3LMC A;  2X7M A;  1PWQ A;  5H8X A;  4PKU A;  4XM8 A;  1QIA A;  1GE7 A;  1GO8 P;  1BKC I;  1AST A;  1IAA A;  2OXZ A;  1SU3 A;  1O0T A;  1R55 A;  1JH1 A;  1XFV A;  1XFU A;  2DW1 A;  1IAE A;  1RMZ A;  2OW9 A;  5BPA A;  1Q3A A;  3NX7 A;  2YB9 A;  4WF6 A;  1AYK A;  1CXV A;  1QJI A;  4PKS A;  3TVC A;  4L19 A;  1KUK A;  2OI0 A;  4WKI A;  4DD8 A;  1OS9 A;  2W12 A;  1B8Y A;  1IAB A;  2WO8 A;  1R1H A;  2D1O A;  3L0V A;  3DSL A;  3WV3 A;  2D1N A;  3TSK A;  5I4O A;  5D7W A;  2L0R A;  4FVL A;  3KMC A;  2JT5 A;  1CAQ A;  1BM6 A;  2MLS A;  3HYG A;  1OM8 A;  4XCT A;  1HTD A;  5I12 A;  3F16 A;  3KME A;  4H49 A;  2CLT A;  4IJO A;  4PKW A;  5B5P A;  1JJ9 A;  1D8F A;  1S4B P;  3EDG A;  1ROS A;  3OHL A;  1ZP5 A;  3EHX A;  2WO9 A;  1GE6 A;  4DV8 A;  1BKC E;  1QJJ A;  2JIH A;  1PWP A;  3F1A A;  3G42 A;  3EDI A;  2USN A;  1BUV M;  1JAQ A;  4WZV A;  2RJQ A;  4A3W A;  1A85 A;  4PKV A;  1USN A;  4GR3 A;  4AXQ A;  3V96 B;  1Y93 A;  1D8M A;  1OS2 A;  1EUB A;  1UMS A;  2X3C A;  2CKI A;  2YIG A;  1G9K A;  2O3E A;  4H76 A;  3ZUK A;  3VTG A;  2OZR A;  2OY2 A;  4A7B A;  1CQR A;  1EB6 A;  2E3X A;  1UMT A;  1ZXV A;  1QIC A;  1CK7 A;  2Z2D A;  4H30 A;  4H82 A;  3LEA A;  1DTH A;  2MZI A;  1I73 A;  1G05 A;  1BQQ M;  3LE9 A;  3O2X A;  1ATL A;  2Y6C A;  3B92 A;  3K7L A;  4DPE A;  1MMB A;  2E2D A;  2WOA A;  4PKR A;  3BA0 A;  4JP4 A;  4JQG A;  4AYK A;  966C A;  3CKI A;  4EFS A;  2DW2 A;  2ERO A;  5B5O A;  1Y0V A;  1L6J A;  3LK8 A;  3UVC A;  3GBO A;  2OY4 A;  1H71 P;  4J4M A;  1JIZ A;  4DF9 A;  3EDZ A;  1GO7 P;  3B8Z A;  3HDA P;  4ZR5 A;  4XBH A;  1BKC A;  2MZE A;  1ZS0 A;  4H2E A;  2MZH A;  3I7I A;  2A8H A;  4AUO A;  3EDH A;  4GR8 A;  2ERQ A;  3ZXH A;  1PWU A;  2K2G A;  3KHI A;  2K9C A;  3LGP A;  3LJZ A;  4PKQ A;  2KRJ A;  1DMT A;  2FV9 A;  2POJ A;  2PJT A;  4AIG A;  4JIJ A;  5D1S A;  4IUW A;  4G9L A;  1SLM A;  1K7I A;  2JNP A;  2ERP A;  2OXW A; 
#chains in the Genus database with same CATH topology
 2X3A A;  4HMA A;  3B2Z A;  1XFW A;  1G12 A;  4QKZ A;  3L0T A;  3HY7 A;  2OW0 A;  3DNG A;  1MMP A;  1MMQ A;  4IN9 A;  4GR0 A;  5BOT A;  5BOY A;  1KUF A;  5L79 A;  1BQO A;  3DPF A;  2W14 A;  1XFY A;  1YOU A;  2OVZ A;  3F18 A;  3KEJ A;  3VI1 A;  2J83 A;  1IAG A;  1XUR A;  1YCM A;  4H3X A;  5L7F A;  3KEK A;  4ILW D;  4HX3 A;  5I3M A;  4ON1 A;  3WV1 A;  3AIG A;  2W15 A;  4L7A A;  1ND1 A;  4WK7 A;  1JAN A;  1I1I P;  5LAB A;  3G5C A;  5I0L A;  3MA2 A;  5CZM A;  1G4K A;  1HFC A;  3SHI A;  1D7X A;  1GKC A;  3ELM A;  3DWB A;  1EAK A;  1CIZ A;  3KRY A;  3N2V A;  3LQB A;  1K7G A;  3LJG A;  1BUD A;  4FU4 A;  3WV2 A;  1SMP A;  4JA1 A;  4I35 A;  3I7G A;  3LUN A;  4WKE A;  5D2B A;  2W13 A;  1UTZ A;  3LKA A;  1KAP P;  1Y8J A;  1HY7 A;  1C3I A;  1K7Q A;  3DTE A;  2JT6 A;  1J7N A;  2DW0 A;  2XS3 A;  1GE5 A;  1CGE A;  2AIG P;  2O36 A;  5CUH A;  4GQL A;  2Y6D A;  4JPA A;  2OVX A;  4R3V A;  3DTI A;  1KUH A;  3HDB A;  4H1Q A;  4PKT A;  4GWN A;  3Q2H A;  1HFS A;  1YQY A;  3F15 A;  4I03 A;  1O0Q A;  1GXD A;  1XUD A;  5JMY A;  1OM7 A;  1OO9 A;  1YP1 A;  2QPJ A;  1JAP A;  4L63 A;  2XS4 A;  1JK3 A;  3LIK A;  3LUM A;  1BSW A;  2OXU A;  5I43 A;  3DPE A;  1QIB A;  1KBC A;  3Q2G A;  2V4B A;  3DTK A;  4Q1L A;  1PWV A;  1MNC A;  2OW2 A;  3F19 A;  3AYU A;  1ZXC A;  4CTH A;  3U1R A;  2OW1 A;  1AF0 A;  2I47 A;  1SAT A;  2TCL A;  1IAC A;  1GKD A;  1BIW A;  2SRT A;  1R1J A;  1CGL A;  3HBU P;  3USN A;  3EWJ A;  4XM7 A;  1HV5 A;  1QUA A;  5D1U A;  1C8T A;  2MLR A;  4FXQ A;  1MMR A;  3P24 A;  1UTT A;  2AYK A;  3KEC A;  3ZVS A;  1ZTQ A;  3OHO A;  2N8R A;  3N2U A;  3O64 A;  4XM6 A;  5D3C A;  3TS4 A;  1XFZ A;  1FM1 A;  2X3B A;  1RM8 A;  1HOV A;  1D5J A;  1KUI A;  1Z3J A;  1ZVX A;  1JAO A;  1KUG A;  1CGF A;  1R1I A;  1JIW P;  2DDF A;  4GWM A;  1SRP A;  3LIL A;  1XM5 A;  3LQ0 A;  1SLN A;  3KWV C;  1XFX A;  2JSD A;  2DDY A;  1TVI A;  3HY9 A;  3TT4 A;  3F17 A;  4H84 A;  2RJP A;  1PWW A;  3P1V A;  2J0T A;  2HU6 A;  1JKY A;  456C A;  1R54 A;  5I2Z A;  3RTS A;  1BZS A;  3EHY A;  3DL1 A;  4G0D A;  1OMJ A;  1WNI A;  1FBL A;  1UEA A;  3LIR A;  4GUY A;  3E8R A;  830C A;  1XUC A;  3LJT A;  4FXY P;  2FV5 A;  3HB2 P;  4GF1 A;  1FLS A;  1A86 A;  1G49 A;  1B3D A;  1IAD A;  1I76 A;  1AKL A;  1C7K A;  2W0D A;  1OM6 A;  5D1T A;  3AYK A;  3HBV P;  3K7N A;  1XAX A;  3RTT A;  4L6T A;  5CXA A;  3LMC A;  2X7M A;  1PWQ A;  5H8X A;  4PKU A;  4XM8 A;  1QIA A;  1GE7 A;  1GO8 P;  1BKC I;  1AST A;  1IAA A;  2OXZ A;  1SU3 A;  1O0T A;  1R55 A;  1JH1 A;  1XFV A;  1XFU A;  2DW1 A;  1IAE A;  1RMZ A;  2OW9 A;  5BPA A;  1Q3A A;  3NX7 A;  2YB9 A;  4WF6 A;  1AYK A;  1CXV A;  1QJI A;  4PKS A;  3TVC A;  2YUF A;  4L19 A;  1KUK A;  2OI0 A;  4WKI A;  4DD8 A;  1OS9 A;  2W12 A;  1B8Y A;  1IAB A;  2WO8 A;  1R1H A;  2D1O A;  3L0V A;  3DSL A;  3WV3 A;  2D1N A;  3TSK A;  5I4O A;  5D7W A;  2L0R A;  4FVL A;  3KMC A;  2JT5 A;  1CAQ A;  1BM6 A;  2MLS A;  3HYG A;  1OM8 A;  4XCT A;  1HTD A;  5I12 A;  3F16 A;  3KME A;  4H49 A;  2CLT A;  4IJO A;  4PKW A;  5B5P A;  1JJ9 A;  1D8F A;  1S4B P;  3EDG A;  1ROS A;  3OHL A;  1ZP5 A;  3EHX A;  2WO9 A;  1GE6 A;  4DV8 A;  1BKC E;  1QJJ A;  2JIH A;  1PWP A;  3F1A A;  3G42 A;  3EDI A;  2USN A;  1BUV M;  1JAQ A;  4WZV A;  2RJQ A;  4A3W A;  1A85 A;  4PKV A;  1USN A;  4GR3 A;  4AXQ A;  3V96 B;  1Y93 A;  1D8M A;  1OS2 A;  1EUB A;  1UMS A;  2X3C A;  2CKI A;  2YIG A;  1G9K A;  2O3E A;  4H76 A;  3ZUK A;  3VTG A;  2OZR A;  2OY2 A;  4A7B A;  1CQR A;  1EB6 A;  2E3X A;  1UMT A;  1ZXV A;  1QIC A;  1CK7 A;  2Z2D A;  4H30 A;  4H82 A;  3LEA A;  1DTH A;  2MZI A;  1I73 A;  1G05 A;  1BQQ M;  3LE9 A;  3O2X A;  1ATL A;  2Y6C A;  3B92 A;  3K7L A;  4DPE A;  1MMB A;  2E2D A;  2WOA A;  4PKR A;  3BA0 A;  4JP4 A;  4JQG A;  4AYK A;  966C A;  3CKI A;  4EFS A;  2DW2 A;  2ERO A;  5B5O A;  1Y0V A;  1L6J A;  3LK8 A;  3UVC A;  3GBO A;  2OY4 A;  1H71 P;  4J4M A;  1JIZ A;  4DF9 A;  3EDZ A;  1GO7 P;  3B8Z A;  3HDA P;  4ZR5 A;  4XBH A;  1BKC A;  2MZE A;  1ZS0 A;  4H2E A;  2MZH A;  3I7I A;  2A8H A;  4AUO A;  3EDH A;  4GR8 A;  2ERQ A;  3ZXH A;  1PWU A;  2K2G A;  3KHI A;  2K9C A;  3LGP A;  3LJZ A;  1OZ9 A;  4PKQ A;  2KRJ A;  1DMT A;  2FV9 A;  2POJ A;  2PJT A;  4AIG A;  4JIJ A;  5D1S A;  4IUW A;  4G9L A;  1SLM A;  1K7I A;  2JNP A;  2ERP A;  2OXW A; 
#chains in the Genus database with same CATH homology
 2X3A A;  4HMA A;  3B2Z A;  1XFW A;  1G12 A;  4QKZ A;  3L0T A;  3HY7 A;  2OW0 A;  3DNG A;  1MMP A;  1MMQ A;  4IN9 A;  4GR0 A;  5BOT A;  5BOY A;  1KUF A;  5L79 A;  1BQO A;  3DPF A;  2W14 A;  1XFY A;  1YOU A;  2OVZ A;  3F18 A;  3KEJ A;  3VI1 A;  2J83 A;  1IAG A;  1XUR A;  1YCM A;  4H3X A;  5L7F A;  3KEK A;  4ILW D;  4HX3 A;  5I3M A;  4ON1 A;  3WV1 A;  3AIG A;  2W15 A;  4L7A A;  1ND1 A;  4WK7 A;  1JAN A;  1I1I P;  5LAB A;  3G5C A;  5I0L A;  3MA2 A;  5CZM A;  1G4K A;  1HFC A;  3SHI A;  1D7X A;  1GKC A;  3ELM A;  3DWB A;  1EAK A;  1CIZ A;  3KRY A;  3N2V A;  3LQB A;  1K7G A;  3LJG A;  1BUD A;  4FU4 A;  3WV2 A;  1SMP A;  4JA1 A;  4I35 A;  3I7G A;  3LUN A;  4WKE A;  5D2B A;  2W13 A;  1UTZ A;  3LKA A;  1KAP P;  1Y8J A;  1HY7 A;  1C3I A;  1K7Q A;  3DTE A;  2JT6 A;  1J7N A;  2DW0 A;  2XS3 A;  1GE5 A;  1CGE A;  2AIG P;  2O36 A;  5CUH A;  4GQL A;  2Y6D A;  4JPA A;  2OVX A;  4R3V A;  3DTI A;  1KUH A;  3HDB A;  4H1Q A;  4PKT A;  4GWN A;  3Q2H A;  1HFS A;  1YQY A;  3F15 A;  4I03 A;  1O0Q A;  1GXD A;  1XUD A;  5JMY A;  1OM7 A;  1OO9 A;  1YP1 A;  2QPJ A;  1JAP A;  4L63 A;  2XS4 A;  1JK3 A;  3LIK A;  3LUM A;  1BSW A;  2OXU A;  5I43 A;  3DPE A;  1QIB A;  1KBC A;  3Q2G A;  2V4B A;  3DTK A;  4Q1L A;  1PWV A;  1MNC A;  2OW2 A;  3F19 A;  3AYU A;  1ZXC A;  4CTH A;  3U1R A;  2OW1 A;  1AF0 A;  2I47 A;  1SAT A;  2TCL A;  1IAC A;  1GKD A;  1BIW A;  2SRT A;  1R1J A;  1CGL A;  3HBU P;  3USN A;  3EWJ A;  4XM7 A;  1HV5 A;  1QUA A;  5D1U A;  1C8T A;  2MLR A;  4FXQ A;  1MMR A;  3P24 A;  1UTT A;  2AYK A;  3KEC A;  3ZVS A;  1ZTQ A;  3OHO A;  2N8R A;  3N2U A;  3O64 A;  4XM6 A;  5D3C A;  3TS4 A;  1XFZ A;  1FM1 A;  2X3B A;  1RM8 A;  1HOV A;  1D5J A;  1KUI A;  1Z3J A;  1ZVX A;  1JAO A;  1KUG A;  1CGF A;  1R1I A;  1JIW P;  2DDF A;  4GWM A;  1SRP A;  3LIL A;  3LQ0 A;  1SLN A;  3KWV C;  1XFX A;  2JSD A;  2DDY A;  3HY9 A;  3TT4 A;  3F17 A;  4H84 A;  2RJP A;  1PWW A;  3P1V A;  2J0T A;  2HU6 A;  1JKY A;  456C A;  1R54 A;  5I2Z A;  3RTS A;  1BZS A;  3EHY A;  3DL1 A;  4G0D A;  1OMJ A;  1WNI A;  1FBL A;  1UEA A;  3LIR A;  4GUY A;  3E8R A;  830C A;  1XUC A;  3LJT A;  4FXY P;  2FV5 A;  3HB2 P;  4GF1 A;  1FLS A;  1A86 A;  1G49 A;  1B3D A;  1IAD A;  1I76 A;  1AKL A;  1C7K A;  2W0D A;  1OM6 A;  5D1T A;  3AYK A;  3HBV P;  3K7N A;  3RTT A;  4L6T A;  5CXA A;  3LMC A;  2X7M A;  1PWQ A;  5H8X A;  4PKU A;  4XM8 A;  1QIA A;  1GE7 A;  1GO8 P;  1BKC I;  1AST A;  1IAA A;  2OXZ A;  1SU3 A;  1O0T A;  1R55 A;  1JH1 A;  1XFV A;  1XFU A;  2DW1 A;  1IAE A;  1RMZ A;  2OW9 A;  5BPA A;  1Q3A A;  3NX7 A;  2YB9 A;  4WF6 A;  1AYK A;  1CXV A;  1QJI A;  4PKS A;  3TVC A;  2YUF A;  4L19 A;  1KUK A;  2OI0 A;  4WKI A;  4DD8 A;  1OS9 A;  2W12 A;  1B8Y A;  1IAB A;  2WO8 A;  1R1H A;  2D1O A;  3L0V A;  3DSL A;  3WV3 A;  2D1N A;  3TSK A;  5I4O A;  5D7W A;  2L0R A;  4FVL A;  3KMC A;  2JT5 A;  1CAQ A;  1BM6 A;  2MLS A;  3HYG A;  1OM8 A;  4XCT A;  1HTD A;  5I12 A;  3F16 A;  3KME A;  4H49 A;  2CLT A;  4IJO A;  4PKW A;  5B5P A;  1JJ9 A;  1D8F A;  1S4B P;  3EDG A;  1ROS A;  3OHL A;  1ZP5 A;  3EHX A;  2WO9 A;  1GE6 A;  4DV8 A;  1BKC E;  1QJJ A;  2JIH A;  1PWP A;  3F1A A;  3G42 A;  3EDI A;  2USN A;  1BUV M;  1JAQ A;  4WZV A;  2RJQ A;  4A3W A;  1A85 A;  4PKV A;  1USN A;  4GR3 A;  4AXQ A;  3V96 B;  1Y93 A;  1D8M A;  1OS2 A;  1EUB A;  1UMS A;  2X3C A;  2CKI A;  2YIG A;  1G9K A;  2O3E A;  4H76 A;  3ZUK A;  3VTG A;  2OZR A;  2OY2 A;  4A7B A;  1CQR A;  1EB6 A;  2E3X A;  1UMT A;  1ZXV A;  1QIC A;  1CK7 A;  2Z2D A;  4H30 A;  4H82 A;  3LEA A;  1DTH A;  2MZI A;  1I73 A;  1G05 A;  1BQQ M;  3LE9 A;  3O2X A;  1ATL A;  2Y6C A;  3B92 A;  3K7L A;  4DPE A;  1MMB A;  2E2D A;  2WOA A;  4PKR A;  3BA0 A;  4JP4 A;  4JQG A;  4AYK A;  966C A;  3CKI A;  4EFS A;  2DW2 A;  2ERO A;  5B5O A;  1Y0V A;  1L6J A;  3LK8 A;  3UVC A;  3GBO A;  2OY4 A;  1H71 P;  4J4M A;  1JIZ A;  4DF9 A;  3EDZ A;  1GO7 P;  3B8Z A;  3HDA P;  4ZR5 A;  4XBH A;  1BKC A;  2MZE A;  1ZS0 A;  4H2E A;  2MZH A;  3I7I A;  2A8H A;  4AUO A;  3EDH A;  4GR8 A;  2ERQ A;  3ZXH A;  1PWU A;  2K2G A;  3KHI A;  2K9C A;  3LGP A;  3LJZ A;  4PKQ A;  2KRJ A;  1DMT A;  2FV9 A;  2POJ A;  2PJT A;  4AIG A;  4JIJ A;  5D1S A;  4IUW A;  4G9L A;  1SLM A;  1K7I A;  2JNP A;  2ERP A;  2OXW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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